메뉴 건너뛰기




Volumn 37, Issue 9, 2007, Pages 2378-2389

DNA demethylation in the human FOXP3 locus discriminates regulatory T cells from activated FOXP3+ conventional T cells

Author keywords

DNA methylation; Epigenetic modifications; Treg marker

Indexed keywords

DNA; TRANSCRIPTION FACTOR FOXP3; TRANSFORMING GROWTH FACTOR BETA;

EID: 34548755672     PISSN: 00142980     EISSN: None     Source Type: Journal    
DOI: 10.1002/eji.200737594     Document Type: Article
Times cited : (585)

References (49)
  • 1
    • 16844365788 scopus 로고    scopus 로고
    • + regulatory T cells in immunological tolerance to self and non-self
    • + regulatory T cells in immunological tolerance to self and non-self. Nat. Immunol. 2005. 6: 345-352.
    • (2005) Nat. Immunol , vol.6 , pp. 345-352
    • Sakaguchi, S.1
  • 2
    • 3543097547 scopus 로고    scopus 로고
    • Suppressor T cells in human diseases
    • Baecher-Allan, C. and Hafler, D. A., Suppressor T cells in human diseases. J. Exp. Med. 2004. 200: 273-276.
    • (2004) J. Exp. Med , vol.200 , pp. 273-276
    • Baecher-Allan, C.1    Hafler, D.A.2
  • 6
    • 28744456154 scopus 로고    scopus 로고
    • Congruent effects of estrogen and T-cell receptor peptide therapy on regulatory T cells in EAE and MS
    • Offner, H. and Vandenbark, A. A., Congruent effects of estrogen and T-cell receptor peptide therapy on regulatory T cells in EAE and MS. Int. Rev. Immunol. 2005. 24: 447-477
    • (2005) Int. Rev. Immunol , vol.24 , pp. 447-477
    • Offner, H.1    Vandenbark, A.A.2
  • 7
    • 33744904725 scopus 로고    scopus 로고
    • + regulatory T-cell function and FOXP3 expression. J. Neurosci. Res. 2006. 83: 1432-1446.
    • + regulatory T-cell function and FOXP3 expression. J. Neurosci. Res. 2006. 83: 1432-1446.
  • 8
    • 33645891652 scopus 로고    scopus 로고
    • An inverse correlation of human peripheral blood regulatory T cell frequency with the disease activity of ulcerative colitis
    • Takahashi, M., Nakamura, K., Honda, K., Kitamura, Y., Mizutani, T., Araki, Y., Kabemura, T. et al., An inverse correlation of human peripheral blood regulatory T cell frequency with the disease activity of ulcerative colitis. Dig. Dis. Sci. 2006. 51: 677-686.
    • (2006) Dig. Dis. Sci , vol.51 , pp. 677-686
    • Takahashi, M.1    Nakamura, K.2    Honda, K.3    Kitamura, Y.4    Mizutani, T.5    Araki, Y.6    Kabemura, T.7
  • 10
    • 16844378685 scopus 로고    scopus 로고
    • Increased populations of regulatory T cells in peripheral blood of patients with hepatocellular carcinoma
    • Ormandy, L. A., Hillemann, T., Wedemeyer, H., Manns, M. P., Greten, T. F. and Korangy, F., Increased populations of regulatory T cells in peripheral blood of patients with hepatocellular carcinoma. Cancer Res. 2005. 65: 2457-2464.
    • (2005) Cancer Res , vol.65 , pp. 2457-2464
    • Ormandy, L.A.1    Hillemann, T.2    Wedemeyer, H.3    Manns, M.P.4    Greten, T.F.5    Korangy, F.6
  • 12
    • 33645286546 scopus 로고    scopus 로고
    • Zou, W., Regulatory T cells, turnout immunity and immunotherapy. Nat. Rev. Immunol. 2006. 6: 295-307.
    • Zou, W., Regulatory T cells, turnout immunity and immunotherapy. Nat. Rev. Immunol. 2006. 6: 295-307.
  • 13
    • 4644237613 scopus 로고    scopus 로고
    • Specific recruitment of regulatory T cells in ovarian carcinoma fosters immune privilege and predicts reduced survival
    • Curiel, T. J., Coukos, G., Zou, L., Alvarez, X, Cheng, P., Mottram, P., Evdemon-Hogan, M. et al. Specific recruitment of regulatory T cells in ovarian carcinoma fosters immune privilege and predicts reduced survival. Nat. Med. 2004. 10: 942-949.
    • (2004) Nat. Med , vol.10 , pp. 942-949
    • Curiel, T.J.1    Coukos, G.2    Zou, L.3    Alvarez, X.4    Cheng, P.5    Mottram, P.6    Evdemon-Hogan, M.7
  • 14
    • 28544433483 scopus 로고    scopus 로고
    • The expression of the regulatory T cell-specific forkhead box transcription factor FoxP3 is associated with poor prognosis in ovarian cancer
    • Wolf, D., Wolf, A. M., Rumpold, H., Fiegl, H., Zeimet A. G., Muller-Holzner, E., Deibl, M. et al., The expression of the regulatory T cell-specific forkhead box transcription factor FoxP3 is associated with poor prognosis in ovarian cancer. Clin. Cancer Res. 2005. 11: 8326-8331.
    • (2005) Clin. Cancer Res , vol.11 , pp. 8326-8331
    • Wolf, D.1    Wolf, A.M.2    Rumpold, H.3    Fiegl, H.4    Zeimet, A.G.5    Muller-Holzner, E.6    Deibl, M.7
  • 17
    • 34248194231 scopus 로고    scopus 로고
    • Tregs and rethinking cancer immunotherapy
    • Curiel, T. J., Tregs and rethinking cancer immunotherapy. J. Clin. Invest. 2007. 117: 1167-1174.
    • (2007) J. Clin. Invest , vol.117 , pp. 1167-1174
    • Curiel, T.J.1
  • 18
    • 34247261531 scopus 로고    scopus 로고
    • Quantification of regulatory T cells enables the identification of high-risk breast cancer patients and those at risk of late relapse
    • Bates, G. J., Fox, S. B., Han, C., Leek, R. D., Garcia, J. F., Harris, A. L. and Banham, A. H., Quantification of regulatory T cells enables the identification of high-risk breast cancer patients and those at risk of late relapse. J. Clin. Oncol. 2006. 24: 5373-5380.
    • (2006) J. Clin. Oncol , vol.24 , pp. 5373-5380
    • Bates, G.J.1    Fox, S.B.2    Han, C.3    Leek, R.D.4    Garcia, J.F.5    Harris, A.L.6    Banham, A.H.7
  • 19
    • 34247277666 scopus 로고    scopus 로고
    • Foxp3 in control of the regulatory T cell lineage
    • Zheng, Y. and Rudensky, A. Y., Foxp3 in control of the regulatory T cell lineage. Nat. Immunol. 2007. 8: 457-462.
    • (2007) Nat. Immunol , vol.8 , pp. 457-462
    • Zheng, Y.1    Rudensky, A.Y.2
  • 21
    • 17044430217 scopus 로고    scopus 로고
    • Identifying Foxp3-expressing suppressor Tcells with a bicistronic reporter
    • Wan, Y. Y. and Flavell, R. A., Identifying Foxp3-expressing suppressor Tcells with a bicistronic reporter. Proc. Natl. Acad. Sci. USA 2005. 102: 5126-5131.
    • (2005) Proc. Natl. Acad. Sci. USA , vol.102 , pp. 5126-5131
    • Wan, Y.Y.1    Flavell, R.A.2
  • 26
    • 33846340789 scopus 로고    scopus 로고
    • FOXP3: Not just for regulatory T cells anymore
    • Ziegler, S. F., FOXP3: Not just for regulatory T cells anymore. Eur. J. Immunol. 2007. 37: 21-23.
    • (2007) Eur. J. Immunol , vol.37 , pp. 21-23
    • Ziegler, S.F.1
  • 31
    • 33947121146 scopus 로고    scopus 로고
    • Transient regulatory T-cells: A state attained by all activated human T-cells
    • Pillai, V., Ortega, S. B., Wang, C. K. and Karandikar, N. J., Transient regulatory T-cells: A state attained by all activated human T-cells. Clin. Immunol. 2007. 123: 18-29.
    • (2007) Clin. Immunol , vol.123 , pp. 18-29
    • Pillai, V.1    Ortega, S.B.2    Wang, C.K.3    Karandikar, N.J.4
  • 34
    • 0035839126 scopus 로고    scopus 로고
    • Epigenetic reprogramming, in mammalian development
    • Reik, W., Dean, W. and Walter, J., Epigenetic reprogramming, in mammalian development. Science 2001. 293: 1089-1093.
    • (2001) Science , vol.293 , pp. 1089-1093
    • Reik, W.1    Dean, W.2    Walter, J.3
  • 35
    • 0036144048 scopus 로고    scopus 로고
    • DNA methylation patterns and epigenetic memory
    • Bird, A., DNA methylation patterns and epigenetic memory. Genes Dev. 2002. 16: 6-21.
    • (2002) Genes Dev , vol.16 , pp. 6-21
    • Bird, A.1
  • 38
    • 15244353967 scopus 로고    scopus 로고
    • X-inactivation profile reveals extensive variability in X-linked gene expression in females
    • Carrel, L. and Willard, H. F., X-inactivation profile reveals extensive variability in X-linked gene expression in females. Nature 2005. 434: 400-404.
    • (2005) Nature , vol.434 , pp. 400-404
    • Carrel, L.1    Willard, H.F.2
  • 39
    • 0033047813 scopus 로고    scopus 로고
    • Methylation profiling of CpG islands in human breast cancer cells
    • Huang, T. H., Perry, M. R. and Laux, D. E., Methylation profiling of CpG islands in human breast cancer cells. Hum. Mol. Genet. 1999. 8: 459-470.
    • (1999) Hum. Mol. Genet , vol.8 , pp. 459-470
    • Huang, T.H.1    Perry, M.R.2    Laux, D.E.3
  • 40
    • 15944387363 scopus 로고    scopus 로고
    • Transforming growth factor-beta-induced regulatory T cells referee inflammatory and autoimmune diseases
    • Wahl, S. M. and Chen, W., Transforming growth factor-beta-induced regulatory T cells referee inflammatory and autoimmune diseases. Arthritis Res. Ther. 2005. 7: 62-68.
    • (2005) Arthritis Res. Ther , vol.7 , pp. 62-68
    • Wahl, S.M.1    Chen, W.2
  • 42
    • 34250863911 scopus 로고    scopus 로고
    • FOXP3 is an X-linked breast cancer suppressor gene and an important repressor of the HER-2/ErbB2 oncogene
    • Zuo, T., Wang, L., Morrison, C., Chang, X, Zhang, H., Li, W., Liu, Y. et al., FOXP3 is an X-linked breast cancer suppressor gene and an important repressor of the HER-2/ErbB2 oncogene. Cell 2007. 129: 1275-1286.
    • (2007) Cell , vol.129 , pp. 1275-1286
    • Zuo, T.1    Wang, L.2    Morrison, C.3    Chang, X.4    Zhang, H.5    Li, W.6    Liu, Y.7
  • 43
    • 0037077285 scopus 로고    scopus 로고
    • A novel family of calmodulin-binding transcription activators in multicellular organisms
    • Bouche, N., Scharlat, A., Snedden, W., Bouchez, D. and Fromm, H., A novel family of calmodulin-binding transcription activators in multicellular organisms. J. Biol. Chem. 2002. 277: 21851-21861.
    • (2002) J. Biol. Chem , vol.277 , pp. 21851-21861
    • Bouche, N.1    Scharlat, A.2    Snedden, W.3    Bouchez, D.4    Fromm, H.5
  • 44
    • 3042656678 scopus 로고    scopus 로고
    • Identification and characterization of FLJ10737 and CAMTA1 genes on the commonly deleted region of neuroblastoma at human chromosome lp36.31-p36.23
    • Katoh, M. and Katoh, M., Identification and characterization of FLJ10737 and CAMTA1 genes on the commonly deleted region of neuroblastoma at human chromosome lp36.31-p36.23. Int. J. Oncol. 2003. 23: 1219-1224.
    • (2003) Int. J. Oncol , vol.23 , pp. 1219-1224
    • Katoh, M.1    Katoh, M.2
  • 45
    • 12944282356 scopus 로고    scopus 로고
    • Cell cycle-dependent transcriptional, regulation of calmodulin-binding transcription activator 1 in neuroblastoma cells
    • Nakatani K., Nishioka, J., Itakura, T., Nakanishi, Y., Horinoucbi, J., Abe, Y. Wada, H. and Nobori, T., Cell cycle-dependent transcriptional, regulation of calmodulin-binding transcription activator 1 in neuroblastoma cells. Int. J. Oncol. 2004. 24: 1407-1412.
    • (2004) Int. J. Oncol , vol.24 , pp. 1407-1412
    • Nakatani, K.1    Nishioka, J.2    Itakura, T.3    Nakanishi, Y.4    Horinoucbi, J.5    Abe, Y.6    Wada, H.7    Nobori, T.8
  • 48
    • 0030471926 scopus 로고    scopus 로고
    • A modified and improved method for bisulphite based cytosine methylation analysis
    • Olek, A., Oswald, J. and Walter, J., A modified and improved method for bisulphite based cytosine methylation analysis. Nucleic Acids Res. 1996. 24: 5064-5066.
    • (1996) Nucleic Acids Res , vol.24 , pp. 5064-5066
    • Olek, A.1    Oswald, J.2    Walter, J.3
  • 49
    • 4544293301 scopus 로고    scopus 로고
    • Quantitative DNA methylation analysis based on four-dye trace data from direct sequencing of PCR amplificates
    • Lewin, J., Schmitt, A. O., Adorjan, P., Hildmann, T. and Piepenbrock, C., Quantitative DNA methylation analysis based on four-dye trace data from direct sequencing of PCR amplificates. Bioinformatics 2004. 20: 3005-3012.
    • (2004) Bioinformatics , vol.20 , pp. 3005-3012
    • Lewin, J.1    Schmitt, A.O.2    Adorjan, P.3    Hildmann, T.4    Piepenbrock, C.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.