Ex vivo expanded human regulatory T cells delay islet allograft rejection via inhibiting islet-derived monocyte chemoattractant protein-1 production in CD34+ stem cells-reconstituted NOD-scid IL2rγnull mice

PLoS ONE

Volumn 9, Issue 3, 2014, Pages

  Xiao, Fang ^a   Ma, Liang ^a,b   Zhao, Min ^a   Huang, Guocai ^a   Mirenda, Vincenzo ^a   Dorling, Anthony ^a   Lechler, Robert ^a   Lombardi, Giovanna ^a  

^a KING'S COLLEGE LONDON   (United Kingdom)

^b QUEEN MARY UNIVERSITY OF LONDON   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

COMPLEMENT COMPONENT C3; GAMMA INTERFERON; IMMUNOGLOBULIN G; IMMUNOGLOBULIN M; INTERLEUKIN 1BETA; INTERLEUKIN 2; INTERLEUKIN 4; INTERLEUKIN 8; LYMPHOTOXIN; MONOCYTE CHEMOTACTIC PROTEIN 1; TUMOR NECROSIS FACTOR ALPHA; CD34 ANTIGEN; INTERLEUKIN 2 RECEPTOR;

ADAPTIVE IMMUNITY; ALLOTRANSPLANTATION; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; B LYMPHOCYTE; CD4+ T LYMPHOCYTE; CELL INFILTRATION; CELL PROLIFERATION; COMPLEMENT DEPOSITION; CONTROLLED STUDY; CORD BLOOD STEM CELL TRANSPLANTATION; DOWN REGULATION; GLUCOSE BLOOD LEVEL; GRAFT REJECTION; GRAFT SURVIVAL; HUMAN; HUMAN CELL; HUMAN TISSUE; INNATE IMMUNITY; MACROPHAGE; MOUSE; NEUTROPHIL; NONHUMAN; PANCREAS ISLET TRANSPLANTATION; PROTEIN ANALYSIS; PROTEIN EXPRESSION; PROTEIN SYNTHESIS INHIBITION; REGULATORY T LYMPHOCYTE; ANIMAL; ANTAGONISTS AND INHIBITORS; BIOSYNTHESIS; COCULTURE; GENETICS; IMMUNOLOGY; IN VITRO STUDY; KNOCKOUT MOUSE; NONOBESE DIABETIC MOUSE; SCID MOUSE; STEM CELL;

ANIMALS; ANTIGENS, CD34; CHEMOKINE CCL2; COCULTURE TECHNIQUES; GRAFT REJECTION; HUMANS; IN VITRO TECHNIQUES; ISLETS OF LANGERHANS TRANSPLANTATION; MICE; MICE, INBRED NOD; MICE, KNOCKOUT; MICE, SCID; RECEPTORS, INTERLEUKIN-2; STEM CELLS; T-LYMPHOCYTES, REGULATORY;

EID: 84896922177     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0090387     Document Type: Article

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