-
1
-
-
0026699089
-
Overview of Parkinson’s disease
-
Duvoisin, R.C. Overview of Parkinson’s disease. Ann. N. Y. Acad. Sci. 1992, 648, 187-193
-
(1992)
Ann. N. Y. Acad. Sci
, vol.648
, pp. 187-193
-
-
Duvoisin, R.C.1
-
2
-
-
0141741347
-
Parkinson’s disease: Mechanisms and models
-
Dauer, W.; Przedborski, S. Parkinson’s disease: Mechanisms and models. Neuron 2003, 39, 889-909
-
(2003)
Neuron
, vol.39
, pp. 889-909
-
-
Dauer, W.1
Przedborski, S.2
-
3
-
-
0242363670
-
Molecular pathways of neurodegeneration in Parkinson’s disease
-
Dawson, T.M.; Dawson, V.L. Molecular pathways of neurodegeneration in Parkinson’s disease. Science 2003, 302, 819-822
-
(2003)
Science
, vol.302
, pp. 819-822
-
-
Dawson, T.M.1
Dawson, V.L.2
-
5
-
-
27644578107
-
Mitochondrial lipid abnormality and electron transport chain impairment in mice lacking alpha-synuclein
-
Ellis, C.E.; Murphy, E.J.; Mitchell, D.C.; Golovko, M.Y.; Scaglia, F.; Barcelo-Coblijn, G.C.; Nussbaum, R.L. Mitochondrial lipid abnormality and electron transport chain impairment in mice lacking alpha-synuclein. Mol. Cell. Biol. 2005, 25, 10190-10201
-
(2005)
Mol. Cell. Biol
, vol.25
, pp. 10190-10201
-
-
Ellis, C.E.1
Murphy, E.J.2
Mitchell, D.C.3
Golovko, M.Y.4
Scaglia, F.5
Barcelo-Coblijn, G.C.6
Nussbaum, R.L.7
-
6
-
-
84863763905
-
Biogenesis of mitochondrial proteins. Adv. Exp. Med
-
Herrmann, J.M.; Longen, S.; Weckbecker, D.; Depuydt, M. Biogenesis of mitochondrial proteins. Adv. Exp. Med. Biol. 2012, 748, 41-64
-
(2012)
Biol
, vol.748
, pp. 41-64
-
-
Herrmann, J.M.1
Longen, S.2
Weckbecker, D.3
Depuydt, M.4
-
7
-
-
34249788738
-
Mitochondria, metabolic disturbances, oxidative stress and the kynurenine system, with focus on neurodegenerative disorders
-
Sas, K.; Robotka, H.; Toldi, J.; Vecsei, L. Mitochondria, metabolic disturbances, oxidative stress and the kynurenine system, with focus on neurodegenerative disorders. J. Neurol. Sci. 2007, 257, 221-239
-
(2007)
J. Neurol. Sci
, vol.257
, pp. 221-239
-
-
Sas, K.1
Robotka, H.2
Toldi, J.3
Vecsei, L.4
-
8
-
-
77953807521
-
Redox signaling (Cross-talk) from and to mitochondria involves mitochondrial pores and reactive oxygen species
-
Daiber, A. Redox signaling (cross-talk) from and to mitochondria involves mitochondrial pores and reactive oxygen species. Biochim. Biophys. Acta 2010, 1797, 897-906
-
(2010)
Biochim. Biophys. Acta
, vol.1797
, pp. 897-906
-
-
Daiber, A.1
-
9
-
-
84859920313
-
Mitochondria-associated membranes (MAMs) as hotspot Ca2+ signaling units
-
Bononi, A.; Missiroli, S.; Poletti, F.; Suski, J.M.; Agnoletto, C.; Bonora, M.; de Marchi, E.; Giorgi, C.; Marchi, S.; Patergnani, S.; et al. Mitochondria-associated membranes (MAMs) as hotspot Ca2+ signaling units. Adv. Exp. Med. Biol. 2012, 740, 411-437
-
(2012)
Adv. Exp. Med. Biol.
, vol.740
, pp. 411-437
-
-
Bononi, A.1
Missiroli, S.2
Poletti, F.3
Suski, J.M.4
Agnoletto, C.5
Bonora, M.6
De Marchi, E.7
Giorgi, C.8
Marchi, S.9
Patergnani, S.10
-
10
-
-
84865427488
-
Mitochondria as sensors and regulators of calcium signalling
-
Rizzuto, R.; de Stefani, D.; Raffaello, A.; Mammucari, C. Mitochondria as sensors and regulators of calcium signalling. Nat. Rev. Mol. Cell Biol. 2012, 13, 566-578
-
(2012)
Nat. Rev. Mol. Cell Biol
, vol.13
, pp. 566-578
-
-
Rizzuto, R.1
De Stefani, D.2
Raffaello, A.3
Mammucari, C.4
-
11
-
-
84859894421
-
Mitochondrial Ca2+ as a key regulator of mitochondrial activities
-
Cali, T.; Ottolini, D.; Brini, M. Mitochondrial Ca2+ as a key regulator of mitochondrial activities. Adv. Exp. Med. Biol. 2012, 942, 53-73
-
(2012)
Adv. Exp. Med. Biol
, vol.942
, pp. 53-73
-
-
Cali, T.1
Ottolini, D.2
Brini, M.3
-
12
-
-
0345600249
-
The division of endosymbiotic organelles
-
Osteryoung, K.W.; Nunnari, J. The division of endosymbiotic organelles. Science 2003, 302, 1698-704
-
(2003)
Science
, vol.302
, pp. 1698-1704
-
-
Osteryoung, K.W.1
Nunnari, J.2
-
13
-
-
84859227392
-
Mitochondrial regulation of cell cycle and proliferation. Antioxid
-
Antico Arciuch, V.G.; Elguero, M.E.; Poderoso, J.J.; Carreras, M.C. Mitochondrial regulation of cell cycle and proliferation. Antioxid. Redox Signal. 2012, 16, 1150-1180
-
(2012)
Redox Signal
, vol.16
, pp. 1150-1180
-
-
Antico Arciuch, V.G.1
Elguero, M.E.2
Poderoso, J.J.3
Carreras, M.C.4
-
14
-
-
0038243184
-
Origins and consequences of mitochondrial variation in vertebrate muscle
-
Moyes, C.D.; Hood, D.A. Origins and consequences of mitochondrial variation in vertebrate muscle. Annu. Rev. Physiol. 2003, 65, 177-201
-
(2003)
Annu. Rev. Physiol
, vol.65
, pp. 177-201
-
-
Moyes, C.D.1
Hood, D.A.2
-
15
-
-
26444552841
-
The significance of mitochondria for embryo development in cloned farm animals
-
Schatten, H.; Prather, R.S.; Sun, Q.Y. The significance of mitochondria for embryo development in cloned farm animals. Mitochondrion 2005, 5, 303-321
-
(2005)
Mitochondrion
, vol.5
, pp. 303-321
-
-
Schatten, H.1
Prather, R.S.2
Sun, Q.Y.3
-
16
-
-
84863218983
-
Mitochondrial Ca2+ and apoptosis
-
Giorgi, C.; Baldassari, F.; Bononi, A.; Bonora, M.; de Marchi, E.; Marchi, S.; Missiroli, S.; Patergnani, S.; Rimessi, A.; Suski, J.M.; et al. Mitochondrial Ca2+ and apoptosis. Cell Calcium 2012, 52, 36-43
-
(2012)
Cell Calcium
, vol.52
, pp. 36-43
-
-
Giorgi, C.1
Baldassari, F.2
Bononi, A.3
Bonora, M.4
De Marchi, E.5
Marchi, S.6
Missiroli, S.7
Patergnani, S.8
Rimessi, A.9
Suski, J.M.10
-
17
-
-
80052627393
-
Mitochondrial permeability transition in Ca2+-dependent apoptosis and necrosis
-
Rasola, A.; Bernardi, P. Mitochondrial permeability transition in Ca2+-dependent apoptosis and necrosis. Cell Calcium 2011, 50, 222-233
-
(2011)
Cell Calcium
, vol.50
, pp. 222-233
-
-
Rasola, A.1
Bernardi, P.2
-
18
-
-
73349091842
-
The role of mitochondria in apoptosis*. Annu
-
Wang, C.; Youle, R.J. The role of mitochondria in apoptosis*. Annu. Rev. Genet. 2009, 43, 95-118
-
(2009)
Rev. Genet
, vol.43
, pp. 95-118
-
-
Wang, C.1
Youle, R.J.2
-
19
-
-
0038727877
-
Transcription factors in the development of midbrain dopamine neurons
-
Burbach, J.P.; Smits, S.; Smidt, M.P. Transcription factors in the development of midbrain dopamine neurons. Ann. N. Y. Acad. Sci. 2003, 991, 61-68
-
(2003)
Ann. N. Y. Acad. Sci
, vol.991
, pp. 61-68
-
-
Burbach, J.P.1
Smits, S.2
Smidt, M.P.3
-
20
-
-
0038389745
-
Transcriptional control of dopamine neuron development
-
Wallen, A.; Perlmann, T. Transcriptional control of dopamine neuron development. Ann. N. Y. Acad. Sci. 2003, 991, 48-60
-
(2003)
Ann. N. Y. Acad. Sci
, vol.991
, pp. 48-60
-
-
Wallen, A.1
Perlmann, T.2
-
21
-
-
0031800728
-
Lee, B. Mutations in LMX1B cause abnormal skeletal patterning and renal dysplasia in nail patella syndrome. Nat
-
Dreyer, S.D.; Zhou, G.; Baldini, A.; Winterpacht, A.; Zabel, B.; Cole, W.; Johnson, R.L.; Lee, B. Mutations in LMX1B cause abnormal skeletal patterning and renal dysplasia in nail patella syndrome. Nat. Genet. 1998, 19, 47-50
-
(1998)
Genet
, vol.19
, pp. 47-50
-
-
Dreyer, S.D.1
Zhou, G.2
Baldini, A.3
Winterpacht, A.4
Zabel, B.5
Cole, W.6
Johnson, R.L.7
-
22
-
-
0030722332
-
A homeodomain gene Ptx3 has highly restricted brain expression in mesencephalic dopaminergic neurons
-
Smidt, M.P.; van Schaick, H.S.; Lanctot, C.; Tremblay, J.J.; Cox, J.J.; van der Kleij, A.A.; Wolterink, G.; Drouin, J.; Burbach, J.P. A homeodomain gene Ptx3 has highly restricted brain expression in mesencephalic dopaminergic neurons. Proc. Natl Acad. Sci. USA 1997, 94, 13305-13310
-
(1997)
Proc. Natl Acad. Sci. USA
, vol.94
, pp. 13305-13310
-
-
Smidt, M.P.1
Van Schaick, H.S.2
Lanctot, C.3
Tremblay, J.J.4
Cox, J.J.5
Van Der Kleij, A.A.6
Wolterink, G.7
Drouin, J.8
Burbach, J.P.9
-
23
-
-
0034034739
-
A second independent pathway for development of mesencephalic dopaminergic neurons requires Lmx1b. Nat
-
Smidt, M.P.; Asbreuk, C.H.; Cox, J.J.; Chen, H.; Johnson, R.L.; Burbach, J.P. A second independent pathway for development of mesencephalic dopaminergic neurons requires Lmx1b. Nat. Neurosci. 2000, 3, 337-341
-
(2000)
Neurosci
, vol.3
, pp. 337-341
-
-
Smidt, M.P.1
Asbreuk, C.H.2
Cox, J.J.3
Chen, H.4
Johnson, R.L.5
Burbach, J.P.6
-
24
-
-
0027995435
-
Iron, and ferritin in Parkinson’s disease substantia nigra
-
Mann, V.M.; Cooper, J.M.; Daniel, S.E.; Srai, K.; Jenner, P.; Marsden, C.D.; Schapira, A.H.; Complex, I, iron, and ferritin in Parkinson’s disease substantia nigra. Ann. Neurol. 1994, 36, 876-881
-
(1994)
Ann. Neurol
, vol.36
, pp. 876-881
-
-
Mann, V.M.1
Cooper, J.M.2
Daniel, S.E.3
Srai, K.4
Jenner, P.5
Marsden, C.D.6
Schapira, A.H.7
Complex, I.8
-
25
-
-
0031965168
-
Quantitative study of mitochondrial complex I in platelets of parkinsonian patients. Mov
-
Blandini, F.; Nappi, G.; Greenamyre, J.T. Quantitative study of mitochondrial complex I in platelets of parkinsonian patients. Mov. Disord. 1998, 13, 11-15
-
(1998)
Disord
, vol.13
, pp. 11-15
-
-
Blandini, F.1
Nappi, G.2
Greenamyre, J.T.3
-
26
-
-
0029050583
-
Low platelet mitochondrial complex I and complex II/III activity in early untreated Parkinson’s disease
-
Haas, R.H.; Nasirian, F.; Nakano, K.; Ward, D.; Pay, M.; Hill, R.; Shults, C.W. Low platelet mitochondrial complex I and complex II/III activity in early untreated Parkinson’s disease. Ann. Neurol. 1995, 37, 714-722
-
(1995)
Ann. Neurol
, vol.37
, pp. 714-722
-
-
Haas, R.H.1
Nasirian, F.2
Nakano, K.3
Ward, D.4
Pay, M.5
Hill, R.6
Shults, C.W.7
-
27
-
-
0027401575
-
Respiratory chain enzyme activities in lymphocytes from untreated patients with Parkinson disease
-
Barroso, N.; Campos, Y.; Huertas, R.; Esteban, J.; Molina, J.A.; Alonso, A.; Gutierrez-Rivas, E.; Arenas, J. Respiratory chain enzyme activities in lymphocytes from untreated patients with Parkinson disease. Clin. Chem. 1993, 39, 667-69
-
(1993)
Clin. Chem
, vol.39
, pp. 667-669
-
-
Barroso, N.1
Campos, Y.2
Huertas, R.3
Esteban, J.4
Molina, J.A.5
Alonso, A.6
Gutierrez-Rivas, E.7
Arenas, J.8
-
28
-
-
0026544129
-
Mitochondrial complex I and II activities of lymphocytes and platelets in Parkinson’s disease
-
Yoshino, H.; Nakagawa-Hattori, Y.; Kondo, T.; Mizuno, Y. Mitochondrial complex I and II activities of lymphocytes and platelets in Parkinson’s disease. J. Neural Transm Parkinsons Dis. Dement. Sect. 1992, 4, 27-34
-
(1992)
J. Neural Transm Parkinsons Dis. Dement. Sect
, vol.4
, pp. 27-34
-
-
Yoshino, H.1
Nakagawa-Hattori, Y.2
Kondo, T.3
Mizuno, Y.4
-
29
-
-
84891645843
-
The role of oxidative stress in Parkinson’s disease
-
Dias, V.; Junn, E.; Mouradian, M.M. The role of oxidative stress in Parkinson’s disease. J. Parkinsons Dis. 2013, 3, 461-491
-
(2013)
J. Parkinsons Dis
, vol.3
, pp. 461-491
-
-
Dias, V.1
Junn, E.2
Mouradian, M.M.3
-
30
-
-
84883180845
-
-
Hwang, O. Role of oxidative stress in Parkinson’s disease
-
Hwang, O. Role of oxidative stress in Parkinson’s disease. Exp. Neurobiol. 2013, 22, 11-17
-
(2013)
Exp. Neurobiol
, vol.22
, pp. 11-17
-
-
-
31
-
-
33646375711
-
Klopstock, T.; et al. High levels of mitochondrial DNA deletions in substantia nigra neurons in aging and Parkinson disease. Nat
-
Bender, A.; Krishnan, K.J.; Morris, C.M.; Taylor, G.A.; Reeve, A.K.; Perry, R.H.; Jaros, E.; Hersheson, J.S.; Betts, J.; Klopstock, T.; et al. High levels of mitochondrial DNA deletions in substantia nigra neurons in aging and Parkinson disease. Nat. Genet. 2006, 38, 515-517
-
(2006)
Genet
, vol.38
, pp. 515-517
-
-
Bender, A.1
Krishnan, K.J.2
Morris, C.M.3
Taylor, G.A.4
Reeve, A.K.5
Perry, R.H.6
Jaros, E.7
Hersheson, J.S.8
Betts, J.9
-
32
-
-
33646351299
-
Mitochondrial DNA deletions are abundant and cause functional impairment in aged human substantia nigra neurons
-
Kraytsberg, Y.; Kudryavtseva, E.; McKee, A.C.; Geula, C.; Kowall, N.W.; Khrapko, K. Mitochondrial DNA deletions are abundant and cause functional impairment in aged human substantia nigra neurons. Nat. Genet. 2006, 38, 518-520
-
(2006)
Nat. Genet
, vol.38
, pp. 518-520
-
-
Kraytsberg, Y.1
Kudryavtseva, E.2
McKee, A.C.3
Geula, C.4
Kowall, N.W.5
Khrapko, K.6
-
33
-
-
0020680904
-
Chronic Parkinsonism in humans due to a product of meperidine-analog synthesis
-
Langston, J.W.; Ballard, P.; Tetrud, J.W.; Irwin, I. Chronic Parkinsonism in humans due to a product of meperidine-analog synthesis. Science 1983, 219, 979-980
-
(1983)
Science
, vol.219
, pp. 979-980
-
-
Langston, J.W.1
Ballard, P.2
Tetrud, J.W.3
Irwin, I.4
-
34
-
-
0033681149
-
Chronic systemic pesticide exposure reproduces features of Parkinson’s disease. Nat
-
Betarbet, R.; Sherer, T.B.; MacKenzie, G.; Garcia-Osuna, M.; Panov, A.V.; Greenamyre, J.T. Chronic systemic pesticide exposure reproduces features of Parkinson’s disease. Nat. Neurosci. 2000, 3, 1301-1306
-
(2000)
Neurosci
, vol.3
, pp. 1301-1306
-
-
Betarbet, R.1
Sherer, T.B.2
Mackenzie, G.3
Garcia-Osuna, M.4
Panov, A.V.5
Greenamyre, J.T.6
-
35
-
-
15544365143
-
Rotenone induces oxidative stress and dopaminergic neuron damage in organotypic substantia nigra cultures
-
Testa, C.M.; Sherer, T.B.; Greenamyre, J.T. Rotenone induces oxidative stress and dopaminergic neuron damage in organotypic substantia nigra cultures. Brain Res. Mol. Brain Res. 2005, 134, 109-118
-
(2005)
Brain Res. Mol. Brain Res
, vol.134
, pp. 109-118
-
-
Testa, C.M.1
Sherer, T.B.2
Greenamyre, J.T.3
-
37
-
-
0005444118
-
Parkinson’s disease in a chemist working with 1-methyl-4- phenyl-1,2,5,6-tetrahydropyridine
-
Langston, J.W.; Ballard, P.A., Jr. Parkinson’s disease in a chemist working with 1-methyl-4- phenyl-1,2,5,6-tetrahydropyridine. N. Engl. J. Med. 1983, 309, 310
-
(1983)
N. Engl. J. Med
, vol.309
-
-
Langston, J.W.1
Ballard, P.A.2
-
38
-
-
0023210581
-
Toxins and Parkinson’s disease: MPTP parkinsonism in humans and animals. Adv
-
Kopin, I.J. Toxins and Parkinson’s disease: MPTP parkinsonism in humans and animals. Adv. Neurol. 1987, 45, 137-144
-
(1987)
Neurol
, vol.45
, pp. 137-144
-
-
Kopin, I.J.1
-
39
-
-
0002758838
-
Parkinson’s disease: Clinical features and etiopahthology
-
Viken, P.J., Bruyn, G.W., Klawans, H.LElsevier Science Publishers: Amsterdam, The Netherlands
-
Barbeau, A. Parkinson’s disease: Clinical features and etiopahthology. In Amsterdam Handbook of Clinical Neurology; Viken, P.J., Bruyn, G.W., Klawans, H.L., Eds.; Elsevier Science Publishers: Amsterdam, The Netherlands, 1986; pp. 87-108
-
(1986)
Amsterdam Handbook of Clinical Neurology
, pp. 87-108
-
-
Barbeau, A.1
-
40
-
-
0031687793
-
Understanding cell death in Parkinson’s disease
-
Jenner, P.; Olanow, C.W. Understanding cell death in Parkinson’s disease. Ann. Neurol. 1998, 44 (Suppl. 1), S72-S84
-
(1998)
Ann. Neurol
, vol.44
, pp. S72-S84
-
-
Jenner, P.1
Olanow, C.W.2
-
41
-
-
0037390135
-
Pitx3 is required for development of substantia nigra dopaminergic neurons
-
Nunes, I.; Tovmasian, L.T.; Silva, R.M.; Burke, R.E.; Goff, S.P. Pitx3 is required for development of substantia nigra dopaminergic neurons. Proc. Natl. Acad. Sci. USA 2003, 100, 4245-4250
-
(2003)
Proc. Natl. Acad. Sci. USA
, vol.100
, pp. 4245-4250
-
-
Nunes, I.1
Tovmasian, L.T.2
Silva, R.M.3
Burke, R.E.4
Goff, S.P.5
-
42
-
-
0038614833
-
Pitx3 is required for motor activity and for survival of a subset of midbrain dopaminergic neurons
-
Van den Munckhof, P.; Luk, K.C.; Ste-Marie, L.; Montgomery, J.; Blanchet, P.J.; Sadikot, A.F.; Drouin, J. Pitx3 is required for motor activity and for survival of a subset of midbrain dopaminergic neurons. Development 2003, 130, 2535-2542
-
(2003)
Development
, vol.130
, pp. 2535-2542
-
-
Van Den Munckhof, P.1
Luk, K.C.2
Ste-Marie, L.3
Montgomery, J.4
Blanchet, P.J.5
Sadikot, A.F.6
Drouin, J.7
-
43
-
-
84872154697
-
Genetics of Parkinson’s disease. Cold Spring Harb. Perspect
-
Klein, C.; Westenberger, A. Genetics of Parkinson’s disease. Cold Spring Harb. Perspect. Med. 2012, 2, a008888
-
(2012)
Med
, vol.2
-
-
Klein, C.1
Westenberger, A.2
-
44
-
-
0031002024
-
Dopamine neuron agenesis in Nurr1-deficient mice
-
Zetterstrom, R.H.; Solomin, L.; Jansson, L.; Hoffer, B.J.; Olson, L.; Perlmann, T. Dopamine neuron agenesis in Nurr1-deficient mice. Science 1997, 276, 248-250
-
(1997)
Science
, vol.276
, pp. 248-250
-
-
Zetterstrom, R.H.1
Solomin, L.2
Jansson, L.3
Hoffer, B.J.4
Olson, L.5
Perlmann, T.6
-
45
-
-
0033572907
-
Fate of mesencephalic AHD2-expressing dopamine progenitor cells in NURR1 mutant mice. Exp
-
Wallen, A.; Zetterstrom, R.H.; Solomin, L.; Arvidsson, M.; Olson, L.; Perlmann, T. Fate of mesencephalic AHD2-expressing dopamine progenitor cells in NURR1 mutant mice. Exp. Cell Res. 1999, 253, 737-46
-
(1999)
Cell Res
, vol.253
, pp. 737-746
-
-
Wallen, A.1
Zetterstrom, R.H.2
Solomin, L.3
Arvidsson, M.4
Olson, L.5
Perlmann, T.6
-
46
-
-
0242499436
-
Molecular mechanisms underlying midbrain dopamine neuron development and function
-
Smidt, M.P.; Smits, S.M.; Burbach, J.P. Molecular mechanisms underlying midbrain dopamine neuron development and function. Eur. J. Pharmacol. 2003, 480, 75-88
-
(2003)
Eur. J. Pharmacol
, vol.480
, pp. 75-88
-
-
Smidt, M.P.1
Smits, S.M.2
Burbach, J.P.3
-
47
-
-
84966930833
-
The Parkinson Disease Mitochondrial Hypothesis: Where Are We at?
-
Franco-Iborra, S.; Vila, M.; Perier, C. The Parkinson Disease Mitochondrial Hypothesis: Where Are We at? Neuroscientist 2015, doi:10.1177/1073858415574600
-
(2015)
Neuroscientist
-
-
Franco-Iborra, S.1
Vila, M.2
Perier, C.3
-
48
-
-
4544273256
-
Parkinsonism, premature menopause, and mitochondrial DNA polymerase gamma mutations: Clinical and molecular genetic study
-
Luoma, P.; Melberg, A.; Rinne, J.O.; Kaukonen, J.A.; Nupponen, N.N.; Chalmers, R.M.; Oldfors, A.; Rautakorpi, I.; Peltonen, L.; Majamaa, K.; et al. Parkinsonism, premature menopause, and mitochondrial DNA polymerase gamma mutations: Clinical and molecular genetic study. Lancet 2004, 364, 875-882
-
(2004)
Lancet
, vol.364
, pp. 875-882
-
-
Luoma, P.1
Melberg, A.2
Rinne, J.O.3
Kaukonen, J.A.4
Nupponen, N.N.5
Chalmers, R.M.6
Oldfors, A.7
Rautakorpi, I.8
Peltonen, L.9
Majamaa, K.10
-
49
-
-
55849122639
-
Mitochondrial biology and oxidative stress in Parkinson disease pathogenesis
-
Henchcliffe, C.; Beal, M.F. Mitochondrial biology and oxidative stress in Parkinson disease pathogenesis. Nat. Clin. Pract. Neurol. 2008, 4, 600-609
-
(2008)
Nat. Clin. Pract. Neurol
, vol.4
, pp. 600-609
-
-
Henchcliffe, C.1
Beal, M.F.2
-
50
-
-
77958072667
-
PGC-1α, a potential therapeutic target for early intervention in Parkinson’s disease
-
52ra73
-
Zheng, B.; Liao, Z.; Locascio, J.J.; Lesniak, K.A.; Roderick, S.S.; Watt, M.L.; Eklund, A.C.; Zhang-James, Y.; Kim, P.D.; Hauser, M.A.; et al. PGC-1α, a potential therapeutic target for early intervention in Parkinson’s disease. Sci. Transl Med. 2010, 2, 52ra73
-
(2010)
Sci. Transl Med
, vol.2
-
-
Zheng, B.1
Liao, Z.2
Locascio, J.J.3
Lesniak, K.A.4
Roderick, S.S.5
Watt, M.L.6
Eklund, A.C.7
Zhang-James, Y.8
Kim, P.D.9
Hauser, M.A.10
-
51
-
-
33846636481
-
Progressive parkinsonism in mice with respiratory-chain-deficient dopamine neurons
-
Ekstrand, M.I.; Terzioglu, M.; Galter, D.; Zhu, S.; Hofstetter, C.; Lindqvist, E.; Thams, S.; Bergstrand, A.; Hansson, F.S.; Trifunovic, A.; et al. Progressive parkinsonism in mice with respiratory-chain-deficient dopamine neurons. Proc. Natl. Acad. Sci. USA 2007, 104, 1325-1330
-
(2007)
Proc. Natl. Acad. Sci. USA
, vol.104
, pp. 1325-1330
-
-
Ekstrand, M.I.1
Terzioglu, M.2
Galter, D.3
Zhu, S.4
Hofstetter, C.5
Lindqvist, E.6
Thams, S.7
Bergstrand, A.8
Hansson, F.S.9
Trifunovic, A.10
-
52
-
-
71849092169
-
The MitoPark Mouse—An animal model of Parkinson’s disease with impaired respiratory chain function in dopamine neurons. Parkinsonism Relat
-
Ekstrand, M.I.; Galter, D. The MitoPark Mouse—An animal model of Parkinson’s disease with impaired respiratory chain function in dopamine neurons. Parkinsonism Relat. Disord. 2009, 15 (Suppl. 3), S185-S188
-
(2009)
Disord
, vol.15
, pp. S185-S188
-
-
Ekstrand, M.I.1
Galter, D.2
-
53
-
-
84925448108
-
Chronic L-DOPA induces hyperactivity, normalization of gait and dyskinetic behavior in MitoPark mice
-
Gellhaar, S.; Marcellino, D.; Abrams, M.B.; Galter, D. Chronic L-DOPA induces hyperactivity, normalization of gait and dyskinetic behavior in MitoPark mice. Genes Brain Behav. 2015, 14, 260-270
-
(2015)
Genes Brain Behav
, vol.14
, pp. 260-270
-
-
Gellhaar, S.1
Marcellino, D.2
Abrams, M.B.3
Galter, D.4
-
54
-
-
0025113789
-
Increase of deleted mitochondrial DNA in the striatum in Parkinson’s disease and senescence. Biochem. Biophys. Res
-
Ikebe, S.; Tanaka, M.; Ohno, K.; Sato, W.; Hattori, K.; Kondo, T.; Mizuno, Y.; Ozawa, T. Increase of deleted mitochondrial DNA in the striatum in Parkinson’s disease and senescence. Biochem. Biophys. Res. Commun. 1990, 170, 1044-1048
-
(1990)
Commun
, vol.170
, pp. 1044-1048
-
-
Ikebe, S.1
Tanaka, M.2
Ohno, K.3
Sato, W.4
Hattori, K.5
Kondo, T.6
Mizuno, Y.7
Ozawa, T.8
-
55
-
-
33749240943
-
Mechanisms of Parkinson’s disease linked to pathological alpha-synuclein
-
Lee, V.M.; Trojanowski, J.Q. Mechanisms of Parkinson’s disease linked to pathological alpha-synuclein: New targets for drug discovery. Neuron 2006, 52, 33-38
-
(2006)
New Targets for Drug Discovery. Neuron
, vol.52
, pp. 33-38
-
-
Lee, V.M.1
Trojanowski, J.Q.2
-
56
-
-
84934983329
-
Synuclein strains cause distinct synucleinopathies after local and systemic administration
-
Peelaerts, W.; Bousset, L.; van der Perren, A.; Moskalyuk, A.; Pulizzi, R.; Giugliano, M.; van den Haute, C.; Melki, R.; Baekelandt, V. Synuclein strains cause distinct synucleinopathies after local and systemic administration. Nature 2015, 522, 340-344
-
(2015)
Nature
, vol.522
, pp. 340-344
-
-
Peelaerts, W.1
Bousset, L.2
Van Der Perren, A.3
Moskalyuk, A.4
Pulizzi, R.5
Giugliano, M.6
Van Den Haute, C.7
Melki, R.8
Baekelandt, V.9
-
57
-
-
84896717868
-
Defining the native state of alpha-synuclein. Neurodegener
-
Selkoe, D.; Dettmer, U.; Luth, E.; Kim, N.; Newman, A.; Bartels, T. Defining the native state of alpha-synuclein. Neurodegener. Dis. 2014, 13, 114-117
-
(2014)
Dis
, vol.13
, pp. 114-117
-
-
Selkoe, D.1
Dettmer, U.2
Luth, E.3
Kim, N.4
Newman, A.5
Bartels, T.6
-
58
-
-
0031668101
-
Genetic dissection of familial Parkinson’s disease. Mol. Med
-
Riess, O.; Jakes, R.; Kruger, R. Genetic dissection of familial Parkinson’s disease. Mol. Med. Today 1998, 4, 438-444
-
(1998)
Today
, vol.4
, pp. 438-444
-
-
Riess, O.1
Jakes, R.2
Kruger, R.3
-
59
-
-
0008209418
-
The genetics of Parkinson’s disease
-
De Silva, H.R.; Khan, N.L.; Wood, N.W. The genetics of Parkinson’s disease. Curr. Opin. Genet. Dev. 2000, 10, 292-298
-
(2000)
Curr. Opin. Genet. Dev
, vol.10
, pp. 292-298
-
-
De Silva, H.R.1
Khan, N.L.2
Wood, N.W.3
-
60
-
-
33646434793
-
Parkin blushed by PINK1
-
Tan, J.M.; Dawson, T.M. Parkin blushed by PINK1. Neuron 2006, 50, 527-529
-
(2006)
Neuron
, vol.50
, pp. 527-529
-
-
Tan, J.M.1
Dawson, T.M.2
-
61
-
-
33746923419
-
Recessive Parkinson’s disease. Mov
-
Kubo, S.; Hattori, N.; Mizuno, Y. Recessive Parkinson’s disease. Mov. Disord. 2006, 21, 885-893
-
(2006)
Disord
, vol.21
, pp. 885-893
-
-
Kubo, S.1
Hattori, N.2
Mizuno, Y.3
-
62
-
-
0037118259
-
Neuronal alpha-synucleinopathy with severe movement disorder in mice expressing A53T human alpha-synuclein
-
Giasson, B.I.; Duda, J.E.; Quinn, S.M.; Zhang, B.; Trojanowski, J.Q.; Lee, V.M. Neuronal alpha-synucleinopathy with severe movement disorder in mice expressing A53T human alpha-synuclein. Neuron 2002, 34, 521-533
-
(2002)
Neuron
, vol.34
, pp. 521-533
-
-
Giasson, B.I.1
Duda, J.E.2
Quinn, S.M.3
Zhang, B.4
Trojanowski, J.Q.5
Lee, V.M.6
-
63
-
-
0037173006
-
Human alpha-synuclein-harboring familial Parkinson’s disease-linked Ala-53 —> Thr mutation causes neurodegenerative disease with alpha-synuclein aggregation in transgenic mice
-
Lee, M.K.; Stirling, W.; Xu, Y.; Xu, X.; Qui, D.; Mandir, A.S.; Dawson, T.M.; Copeland, N.G.; Jenkins, N.A.; Price, D.L. Human alpha-synuclein-harboring familial Parkinson’s disease-linked Ala-53 —> Thr mutation causes neurodegenerative disease with alpha-synuclein aggregation in transgenic mice. Proc. Natl. Acad. Sci. USA 2002, 99, 8968-8973
-
(2002)
Proc. Natl. Acad. Sci. USA
, vol.99
, pp. 8968-8973
-
-
Lee, M.K.1
Stirling, W.2
Xu, Y.3
Xu, X.4
Qui, D.5
Mandir, A.S.6
Dawson, T.M.7
Copeland, N.G.8
Jenkins, N.A.9
Price, D.L.10
-
64
-
-
10744221260
-
Transgenic mice expressing mutant A53T human alpha-synuclein show neuronal dysfunction in the absence of aggregate formation
-
Gispert, S.; Del Turco, D.; Garrett, L.; Chen, A.; Bernard, D.J.; Hamm-Clement, J.; Korf, H.W.; Deller, T.; Braak, H.; Auburger, G.; et al. Transgenic mice expressing mutant A53T human alpha-synuclein show neuronal dysfunction in the absence of aggregate formation. Mol. Cell. Neurosci. 2003, 24, 419-429
-
(2003)
Mol. Cell. Neurosci.
, vol.24
, pp. 419-429
-
-
Gispert, S.1
Del Turco, D.2
Garrett, L.3
Chen, A.4
Bernard, D.J.5
Hamm-Clement, J.6
Korf, H.W.7
Deller, T.8
Braak, H.9
Auburger, G.10
-
65
-
-
0036855635
-
Misfolded proteinase K-resistant hyperphosphorylated alpha-synuclein in aged transgenic mice with locomotor deterioration and in human alpha-synucleinopathies
-
Neumann, M.; Kahle, P.J.; Giasson, B.I.; Ozmen, L.; Borroni, E.; Spooren, W.; Muller, V.; Odoy, S.; Fujiwara, H.; Hasegawa, M.; et al. Misfolded proteinase K-resistant hyperphosphorylated alpha-synuclein in aged transgenic mice with locomotor deterioration and in human alpha-synucleinopathies. J. Clin. Investig. 2002, 110, 1429-11439
-
(2002)
J. Clin. Investig.
, vol.110
, pp. 1429-11439
-
-
Neumann, M.1
Kahle, P.J.2
Giasson, B.I.3
Ozmen, L.4
Borroni, E.5
Spooren, W.6
Muller, V.7
Odoy, S.8
Fujiwara, H.9
Hasegawa, M.10
-
66
-
-
0036605566
-
Differential neuropathological alterations in transgenic mice expressing alpha-synuclein from the platelet-derived growth factor and Thy-1 promoters
-
Rockenstein, E.; Mallory, M.; Hashimoto, M.; Song, D.; Shults, C.W.; Lang, I.; Masliah, E. Differential neuropathological alterations in transgenic mice expressing alpha-synuclein from the platelet-derived growth factor and Thy-1 promoters. J. Neurosci. Res. 2002, 68, 568-578
-
(2002)
J. Neurosci. Res.
, vol.68
, pp. 568-578
-
-
Rockenstein, E.1
Mallory, M.2
Hashimoto, M.3
Song, D.4
Shults, C.W.5
Lang, I.6
Masliah, E.7
-
67
-
-
7044270767
-
Early and progressive sensorimotor anomalies in mice overexpressing wild-type human alpha-synuclein
-
Fleming, S.M.; Salcedo, J.; Fernagut, P.O.; Rockenstein, E.; Masliah, E.; Levine, M.S.; Chesselet, M.F. Early and progressive sensorimotor anomalies in mice overexpressing wild-type human alpha-synuclein. J. Neurosci. 2004, 24, 9434-9440
-
(2004)
J. Neurosci
, vol.24
, pp. 9434-9440
-
-
Fleming, S.M.1
Salcedo, J.2
Fernagut, P.O.3
Rockenstein, E.4
Masliah, E.5
Levine, M.S.6
Chesselet, M.F.7
-
68
-
-
84921456454
-
A53T human alpha-synuclein overexpression in transgenic mice induces pervasive mitochondria macroautophagy defects preceding dopamine neuron degeneration
-
Chen, L.; Xie, Z.; Turkson, S.; Zhuang, X. A53T human alpha-synuclein overexpression in transgenic mice induces pervasive mitochondria macroautophagy defects preceding dopamine neuron degeneration. J. Neurosci. 2015, 35, 890-905
-
(2015)
J. Neurosci
, vol.35
, pp. 890-905
-
-
Chen, L.1
Xie, Z.2
Turkson, S.3
Zhuang, X.4
-
69
-
-
67649813448
-
Mutant LRRK2(R1441G) BAC transgenic mice recapitulate cardinal features of Parkinson’s diseaseNat
-
Li, Y.; Liu, W.; Oo, T.F.; Wang, L.; Tang, Y.; Jackson-Lewis, V.; Zhou, C.; Geghman, K.; Bogdanov, M.; Przedborski, S.; et al. Mutant LRRK2(R1441G) BAC transgenic mice recapitulate cardinal features of Parkinson’s disease. Nat. Neurosci. 2009, 12, 826-828
-
(2009)
Neurosci
, vol.12
, pp. 826-828
-
-
Li, Y.1
Liu, W.2
Oo, T.F.3
Wang, L.4
Tang, Y.5
Jackson-Lewis, V.6
Zhou, C.7
Geghman, K.8
Bogdanov, M.9
Przedborski, S.10
-
70
-
-
84907997127
-
A novel mitochondrially-targeted apocynin derivative prevents hyposmia and loss of motor function in the leucine-rich repeat kinase 2 (LRRK2(R1441G)) transgenic mouse model of Parkinson’s disease
-
Dranka, B.P.; Gifford, A.; McAllister, D.; Zielonka, J.; Joseph, J.; O'Hara, C.L.; Stucky, C.L.; Kanthasamy, A.G.; Kalyanaraman, B. A novel mitochondrially-targeted apocynin derivative prevents hyposmia and loss of motor function in the leucine-rich repeat kinase 2 (LRRK2(R1441G)) transgenic mouse model of Parkinson’s disease. Neurosci. Lett. 2014, 583, 159-164
-
(2014)
Neurosci. Lett
, vol.583
, pp. 159-164
-
-
Dranka, B.P.1
Gifford, A.2
McAllister, D.3
Zielonka, J.4
Joseph, J.5
O'hara, C.L.6
Stucky, C.L.7
Kanthasamy, A.G.8
Kalyanaraman, B.9
-
71
-
-
84928594767
-
Progressive dopaminergic alterations and mitochondrial abnormalities in LRRK2 G2019S knock-in mice. Neurobiol
-
Yue, M.; Hinkle, K.M.; Davies, P.; Trushina, E.; Fiesel, F.C.; Christenson, T.A.; Schroeder, A.S.; Zhang, L.; Bowles, E.; Behrouz, B.; et al. Progressive dopaminergic alterations and mitochondrial abnormalities in LRRK2 G2019S knock-in mice. Neurobiol. Dis. 2015, 78, 172-195
-
(2015)
Dis
, vol.78
, pp. 172-195
-
-
Yue, M.1
Hinkle, K.M.2
Davies, P.3
Trushina, E.4
Fiesel, F.C.5
Christenson, T.A.6
Schroeder, A.S.7
Zhang, L.8
Bowles, E.9
Behrouz, B.10
-
72
-
-
0141891953
-
Parkin-deficient mice exhibit nigrostriatal deficits but not loss of dopaminergic neurons
-
Goldberg, M.S.; Fleming, S.M.; Palacino, J.J.; Cepeda, C.; Lam, H.A.; Bhatnagar, A.; Meloni, E.G.; Wu, N.; Ackerson, L.C.; Klapstein, G.J.; et al. Parkin-deficient mice exhibit nigrostriatal deficits but not loss of dopaminergic neurons. J. Biol. Chem. 2003, 278, 43628-43635
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 43628-43635
-
-
Goldberg, M.S.1
Fleming, S.M.2
Palacino, J.J.3
Cepeda, C.4
Lam, H.A.5
Bhatnagar, A.6
Meloni, E.G.7
Wu, N.8
Ackerson, L.C.9
Klapstein, G.J.10
-
73
-
-
13844313915
-
Parkin-deficient mice are not a robust model of parkinsonism
-
Perez, F.A.; Palmiter, R.D. Parkin-deficient mice are not a robust model of parkinsonism. Proc. Natl. Acad. Sci. USA 2005, 102, 2174-2179
-
(2005)
Proc. Natl. Acad. Sci. USA
, vol.102
, pp. 2174-2179
-
-
Perez, F.A.1
Palmiter, R.D.2
-
74
-
-
84899742956
-
Brain mitochondria from DJ-1 knockout mice show increased respiration-dependent hydrogen peroxide consumption
-
Lopert, P.; Patel, M. Brain mitochondria from DJ-1 knockout mice show increased respiration-dependent hydrogen peroxide consumption. Redox Biol. 2014, 2, 667-672
-
(2014)
Redox Biol
, vol.2
, pp. 667-672
-
-
Lopert, P.1
Patel, M.2
-
75
-
-
79251543343
-
Increased mitochondrial calcium sensitivity and abnormal expression of innate immunity genes precede dopaminergic defects in Pink1-deficient mice
-
Akundi, R.S.; Huang, Z.; Eason, J.; Pandya, J.D.; Zhi, L.; Cass, W.A.; Sullivan, P.G.; Bueler, H. Increased mitochondrial calcium sensitivity and abnormal expression of innate immunity genes precede dopaminergic defects in Pink1-deficient mice. PLoS ONE 2011, 6, e16038
-
(2011)
Plos ONE
, vol.6
-
-
Akundi, R.S.1
Huang, Z.2
Eason, J.3
Pandya, J.D.4
Zhi, L.5
Cass, W.A.6
Sullivan, P.G.7
Bueler, H.8
-
76
-
-
66749163493
-
Parkinson phenotype in aged PINK1-deficient mice is accompanied by progressive mitochondrial dysfunction in absence of neurodegeneration
-
Gispert, S.; Ricciardi, F.; Kurz, A.; Azizov, M.; Hoepken, H.H.; Becker, D.; Voos, W.; Leuner, K.; Muller, W.E.; Kudin, A.P.; et al. Parkinson phenotype in aged PINK1-deficient mice is accompanied by progressive mitochondrial dysfunction in absence of neurodegeneration. PLoS ONE 2009, 4, e5777
-
(2009)
Plos ONE
, vol.4
-
-
Gispert, S.1
Ricciardi, F.2
Kurz, A.3
Azizov, M.4
Hoepken, H.H.5
Becker, D.6
Voos, W.7
Leuner, K.8
Muller, W.E.9
Kudin, A.P.10
-
77
-
-
34249946941
-
Mono-and double-mutant mouse models of Parkinson’s disease display severe mitochondrial damage. Hum. Mol
-
Stichel, C.C.; Zhu, X.R.; Bader, V.; Linnartz, B.; Schmidt, S.; Lubbert, H. Mono-and double-mutant mouse models of Parkinson’s disease display severe mitochondrial damage. Hum. Mol. Genet. 2007, 16, 2377-2393
-
(2007)
Genet
, vol.16
, pp. 2377-2393
-
-
Stichel, C.C.1
Zhu, X.R.2
Bader, V.3
Linnartz, B.4
Schmidt, S.5
Lubbert, H.6
-
78
-
-
1642379155
-
Linking DJ-1 to neurodegeneration offers novel insights for understanding the pathogenesis of Parkinson’s disease
-
Bonifati, V.; Oostra, B.A.; Heutink, P. Linking DJ-1 to neurodegeneration offers novel insights for understanding the pathogenesis of Parkinson’s disease. J. Mol. Med. (Berl.) 2004, 82, 163-174
-
(2004)
J. Mol. Med. (Berl.)
, vol.82
, pp. 163-174
-
-
Bonifati, V.1
Oostra, B.A.2
Heutink, P.3
-
79
-
-
5444272172
-
Causes of Parkinson’s disease: Genetics of DJ-1
-
Abou-Sleiman, P.M.; Healy, D.G.; Wood, N.W. Causes of Parkinson’s disease: Genetics of DJ-1. Cell Tissue Res. 2004, 318, 185-188
-
(2004)
Cell Tissue Res
, vol.318
, pp. 185-188
-
-
Abou-Sleiman, P.M.1
Healy, D.G.2
Wood, N.W.3
-
80
-
-
8844233579
-
Mutations in LRRK2 cause autosomal-dominant parkinsonism with pleomorphic pathology
-
Zimprich, A.; Biskup, S.; Leitner, P.; Lichtner, P.; Farrer, M.; Lincoln, S.; Kachergus, J.; Hulihan, M.; Uitti, R.J.; Calne, D.B.; et al. Mutations in LRRK2 cause autosomal-dominant parkinsonism with pleomorphic pathology. Neuron 2004, 44, 601-607
-
(2004)
Neuron
, vol.44
, pp. 601-607
-
-
Zimprich, A.1
Biskup, S.2
Leitner, P.3
Lichtner, P.4
Farrer, M.5
Lincoln, S.6
Kachergus, J.7
Hulihan, M.8
Uitti, R.J.9
Calne, D.B.10
-
81
-
-
8844266996
-
Cloning of the gene containing mutations that cause PARK8-linked Parkinson’s disease
-
Paisan-Ruiz, C.; Jain, S.; Evans, E.W.; Gilks, W.P.; Simon, J.; van der Brug, M.; de Munain, A.L.; Aparicio, S.; Gil, A.M.; Khan, N.; et al. Cloning of the gene containing mutations that cause PARK8-linked Parkinson’s disease. Neuron 2004, 44, 595-600
-
(2004)
Neuron
, vol.44
, pp. 595-600
-
-
Paisan-Ruiz, C.1
Jain, S.2
Evans, E.W.3
Gilks, W.P.4
Simon, J.5
Van Der Brug, M.6
De Munain, A.L.7
Aparicio, S.8
Gil, A.M.9
Khan, N.10
-
82
-
-
33846562487
-
Parkinson’s disease-associated mutations in LRRK2 link enhanced GTP-binding and kinase activities to neuronal toxicity
-
West, A.B.; Moore, D.J.; Choi, C.; Andrabi, S.A.; Li, X.; Dikeman, D.; Biskup, S.; Zhang, Z.; Lim, K.L.; Dawson, V.L.; et al. Parkinson’s disease-associated mutations in LRRK2 link enhanced GTP-binding and kinase activities to neuronal toxicity. Hum. Mol. Genet. 2007, 16, 223-232
-
(2007)
Hum. Mol. Genet.
, vol.16
, pp. 223-232
-
-
West, A.B.1
Moore, D.J.2
Choi, C.3
Andrabi, S.A.4
Li, X.5
Dikeman, D.6
Biskup, S.7
Zhang, Z.8
Lim, K.L.9
Dawson, V.L.10
-
83
-
-
78649389313
-
The role of leucinerich repeat kinase 2 (LRRK2) in Parkinson’s disease
-
Cookson, M.R. The role of leucinerich repeat kinase 2 (LRRK2) in Parkinson’s disease. Nat. Rev. Neurosci. 2010, 11, 791-797
-
(2010)
Nat. Rev. Neurosci
, vol.11
, pp. 791-797
-
-
Cookson, M.R.1
-
84
-
-
28044460070
-
Parkinson’s disease-associated mutations in leucine-rich repeat kinase 2 augment kinase activity
-
West, A.B.; Moore, D.J.; Biskup, S.; Bugayenko, A.; Smith, W.W.; Ross, C.A.; Dawson, V.L.; Dawson, T.M. Parkinson’s disease-associated mutations in leucine-rich repeat kinase 2 augment kinase activity. Proc. Natl. Acad. Sci. USA 2005, 102, 16842-16847
-
(2005)
Proc. Natl. Acad. Sci. USA
, vol.102
, pp. 16842-16847
-
-
West, A.B.1
Moore, D.J.2
Biskup, S.3
Bugayenko, A.4
Smith, W.W.5
Ross, C.A.6
Dawson, V.L.7
Dawson, T.M.8
-
85
-
-
0035341443
-
Fate of midbrain dopaminergic neurons controlled by the engrailed genes
-
Simon, H.H.; Saueressig, H.; Wurst, W.; Goulding, M.D.; O'Leary, D.D. Fate of midbrain dopaminergic neurons controlled by the engrailed genes. J. Neurosci. 2001, 21, 3126-3134
-
(2001)
J. Neurosci
, vol.21
, pp. 3126-3134
-
-
Simon, H.H.1
Saueressig, H.2
Wurst, W.3
Goulding, M.D.4
O'leary, D.D.5
-
86
-
-
84877282837
-
Impairment of mitochondrial dynamics: A target for the treatment of neurological disorders?
-
Yu-chin Su, X.Q.; Impairment of mitochondrial dynamics: A target for the treatment of neurological disorders? Future Med. 2013, 8, 333-346
-
(2013)
Future Med
, vol.8
, pp. 333-346
-
-
Yu-Chin Su, X.Q.1
-
87
-
-
0029937494
-
Epidemiology of Parkinson’s disease. Neurol
-
Tanner, C.M.; Goldman, S.M. Epidemiology of Parkinson’s disease. Neurol. Clin. 1996, 14, 317-35
-
(1996)
Clin
, vol.14
, pp. 317-335
-
-
Tanner, C.M.1
Goldman, S.M.2
-
88
-
-
0026632955
-
Is the prevalence of Parkinson’s disease in New Zealand really changing? Acta Neurol
-
Caradoc-Davies, T.H.; Weatherall, M.; Dixon, G.S.; Caradoc-Davies, G.; Hantz, P. Is the prevalence of Parkinson’s disease in New Zealand really changing? Acta Neurol. Scand. 1992, 86, 40-44
-
(1992)
Scand
, vol.86
, pp. 40-44
-
-
Caradoc-Davies, T.H.1
Weatherall, M.2
Dixon, G.S.3
Caradoc-Davies, G.4
Hantz, P.5
-
89
-
-
0026786260
-
Prevalence of Parkinson’s disease and other types of parkinsonism: A door-to-door survey in three Sicilian municipalities. The Sicilian Neuro-Epidemiologic Study (SNES) Group
-
Morgante, L.; Rocca, W.A.; di Rosa, A.E.; de Domenico, P.; Grigoletto, F.; Meneghini, F.; Reggio, A.; Savettieri, G.; Castiglione, M.G.; Patti, F.; et al. Prevalence of Parkinson’s disease and other types of parkinsonism: A door-to-door survey in three Sicilian municipalities. The Sicilian Neuro-Epidemiologic Study (SNES) Group. Neurology 1992, 42, 1901-1907
-
(1992)
Neurology
, vol.42
, pp. 1901-1907
-
-
Morgante, L.1
Rocca, W.A.2
Di Rosa, A.E.3
De Domenico, P.4
Grigoletto, F.5
Meneghini, F.6
Reggio, A.7
Savettieri, G.8
Castiglione, M.G.9
Patti, F.10
-
90
-
-
0022626549
-
Parkinson’s disease in a Scottish city
-
Mutch, W.J.; Dingwall-Fordyce, I.; Downie, A.W.; Paterson, J.G.; Roy, S.K. Parkinson’s disease in a Scottish city. Br. Med. J. (Clin. Res. Ed.) 1986, 292, 534-536
-
(1986)
Br. Med. J. (Clin. Res. Ed.)
, vol.292
, pp. 534-536
-
-
Mutch, W.J.1
Dingwall-Fordyce, I.2
Downie, A.W.3
Paterson, J.G.4
Roy, S.K.5
-
91
-
-
10544234193
-
Mapping of a gene for Parkinson’s disease to chromosome 4q21-q23
-
Polymeropoulos, M.H.; Higgins, J.J.; Golbe, L.I.; Johnson, W.G.; Ide, S.E.; di Iorio, G.; Sanges, G.; Stenroos, E.S.; Pho, L.T.; Schaffer, A.A.; et al. Mapping of a gene for Parkinson’s disease to chromosome 4q21-q23. Science 1996, 274, 1197-1199
-
(1996)
Science
, vol.274
, pp. 1197-1199
-
-
Polymeropoulos, M.H.1
Higgins, J.J.2
Golbe, L.I.3
Johnson, W.G.4
Ide, S.E.5
Di Iorio, G.6
Sanges, G.7
Stenroos, E.S.8
Pho, L.T.9
Schaffer, A.A.10
-
92
-
-
0042767676
-
Parkinson’s disease: Piecing together a genetic jigsaw
-
Dekker, M.C.; Bonifati, V.; van Duijn, C.M. Parkinson’s disease: Piecing together a genetic jigsaw. Brain 2003, 126, 1722-1733
-
(2003)
Brain
, vol.126
, pp. 1722-1733
-
-
Dekker, M.C.1
Bonifati, V.2
Van Duijn, C.M.3
-
93
-
-
0031715849
-
Epidemiology versus genetics in Parkinson’s disease: Progress in resolving an age-old debate
-
Langston, J.W. Epidemiology versus genetics in Parkinson’s disease: Progress in resolving an age-old debate. Ann. Neurol. 1998, 44 (Suppl. 1), S45-S52
-
(1998)
Ann. Neurol
, vol.44
, pp. S45-S52
-
-
Langston, J.W.1
-
94
-
-
0031105553
-
Gene therapeutic strategies for neuroprotection: Implications for Parkinson’s disease. Exp
-
Bowers, W.J.; Howard, D.F.; Federoff, H.J. Gene therapeutic strategies for neuroprotection: Implications for Parkinson’s disease. Exp. Neurol. 1997, 144, 58-68
-
(1997)
Neurol
, vol.144
, pp. 58-68
-
-
Bowers, W.J.1
Howard, D.F.2
Federoff, H.J.3
-
95
-
-
0032499264
-
Mutations in the parkin gene cause autosomal recessive juvenile parkinsonism
-
Kitada, T.; Asakawa, S.; Hattori, N.; Matsumine, H.; Yamamura, Y.; Minoshima, S.; Yokochi, M.; Mizuno, Y.; Shimizu, N. Mutations in the parkin gene cause autosomal recessive juvenile parkinsonism. Nature 1998, 392, 605-608
-
(1998)
Nature
, vol.392
, pp. 605-608
-
-
Kitada, T.1
Asakawa, S.2
Hattori, N.3
Matsumine, H.4
Yamamura, Y.5
Minoshima, S.6
Yokochi, M.7
Mizuno, Y.8
Shimizu, N.9
-
96
-
-
0033525009
-
Low frequency of pathogenic mutations in the ubiquitin carboxy-terminal hydrolase gene in familial Parkinson’s disease
-
Lincoln, S.; Vaughan, J.; Wood, N.; Baker, M.; Adamson, J.; Gwinn-Hardy, K.; Lynch, T.; Hardy, J.; Farrer, M. Low frequency of pathogenic mutations in the ubiquitin carboxy-terminal hydrolase gene in familial Parkinson’s disease. Neuroreport 1999, 10, 427-429
-
(1999)
Neuroreport
, vol.10
, pp. 427-429
-
-
Lincoln, S.1
Vaughan, J.2
Wood, N.3
Baker, M.4
Adamson, J.5
Gwinn-Hardy, K.6
Lynch, T.7
Hardy, J.8
Farrer, M.9
-
97
-
-
0025344485
-
Large kindred with autosomal dominant Parkinson’s disease
-
Golbe, L.I.; Di Iorio, G.; Bonavita, V.; Miller, D.C.; Duvoisin, R.C. A large kindred with autosomal dominant Parkinson’s disease. Ann. Neurol. 1990, 27, 276-282
-
(1990)
Ann. Neurol
, vol.27
, pp. 276-282
-
-
Golbe, L.I.1
Di Iorio, G.2
Bonavita, V.3
Miller, D.C.4
Duvoisin, R.5
-
98
-
-
0031990490
-
Ala30Pro mutation in the gene encoding alpha-synuclein in Parkinson’s disease. Nat
-
Kruger, R.; Kuhn, W.; Muller, T.; Woitalla, D.; Graeber, M.; Kosel, S.; Przuntek, H.; Epplen, J.T.; Schols, L.; Riess, O. Ala30Pro mutation in the gene encoding alpha-synuclein in Parkinson’s disease. Nat. Genet. 1998, 18, 106-108
-
(1998)
Genet
, vol.18
, pp. 106-108
-
-
Kruger, R.1
Kuhn, W.2
Muller, T.3
Woitalla, D.4
Graeber, M.5
Kosel, S.6
Przuntek, H.7
Epplen, J.T.8
Schols, L.9
Riess, O.10
-
99
-
-
0030744876
-
Mutation in the alpha-synuclein gene identified in families with Parkinson’s disease
-
Polymeropoulos, M.H.; Lavedan, C.; Leroy, E.; Ide, S.E.; Dehejia, A.; Dutra, A.; Pike, B.; Root, H.; Rubenstein, J.; Boyer, R.; et al. Mutation in the alpha-synuclein gene identified in families with Parkinson’s disease. Science 1997, 276, 2045-2047
-
(1997)
Science
, vol.276
, pp. 2045-2047
-
-
Polymeropoulos, M.H.1
Lavedan, C.2
Leroy, E.3
Ide, S.E.4
Dehejia, A.5
Dutra, A.6
Pike, B.7
Root, H.8
Rubenstein, J.9
Boyer, R.10
-
100
-
-
84868127674
-
Loss of Mfn2 results in progressive, retrograde degeneration of dopaminergic neurons in the nigrostriatal circuit. Hum. Mol
-
Pham, A.H.; Meng, S.; Chu, Q.N.; Chan, D.C. Loss of Mfn2 results in progressive, retrograde degeneration of dopaminergic neurons in the nigrostriatal circuit. Hum. Mol. Genet. 2012, 21, 4817-4826
-
(2012)
Genet
, vol.21
, pp. 4817-4826
-
-
Pham, A.H.1
Meng, S.2
Chu, Q.N.3
Chan, D.C.4
-
101
-
-
84868110583
-
Mitofusin 2 is necessary for striatal axonal projections of midbrain dopamine neurons. Hum. Mol
-
Lee, S.; Sterky, F.H.; Mourier, A.; Terzioglu, M.; Cullheim, S.; Olson, L.; Larsson, N.G. Mitofusin 2 is necessary for striatal axonal projections of midbrain dopamine neurons. Hum. Mol. Genet. 2012, 21, 4827-35
-
(2012)
Genet
, vol.21
, pp. 4827-4835
-
-
Lee, S.1
Sterky, F.H.2
Mourier, A.3
Terzioglu, M.4
Cullheim, S.5
Olson, L.6
Larsson, N.G.7
-
102
-
-
41149111891
-
Bcl-xL induces Drp1-dependent synapse formation in cultured hippocampal neurons
-
Li, H.; Chen, Y.; Jones, A.F.; Sanger, R.H.; Collis, L.P.; Flannery, R.; McNay, E.C.; Yu, T.; Schwarzenbacher, R.; Bossy, B.; et al. Bcl-xL induces Drp1-dependent synapse formation in cultured hippocampal neurons. Proc. Natl. Acad. Sci. USA 2008, 105, 2169-2174
-
(2008)
Proc. Natl. Acad. Sci. USA
, vol.105
, pp. 2169-2174
-
-
Li, H.1
Chen, Y.2
Jones, A.F.3
Sanger, R.H.4
Collis, L.P.5
Flannery, R.6
McNay, E.C.7
Yu, T.8
Schwarzenbacher, R.9
Bossy, B.10
-
103
-
-
68249087424
-
Mitochondrial fission factor Drp1 is essential for embryonic development and synapse formation in mice
-
Ishihara, N.; Nomura, M.; Jofuku, A.; Kato, H.; Suzuki, S.O.; Masuda, K.; Otera, H.; Nakanishi, Y.; Nonaka, I.; Goto, Y.; et al. Mitochondrial fission factor Drp1 is essential for embryonic development and synapse formation in mice. Nat. Cell. Biol. 2009, 11, 958-966
-
(2009)
Nat. Cell. Biol.
, vol.11
, pp. 958-966
-
-
Ishihara, N.1
Nomura, M.2
Jofuku, A.3
Kato, H.4
Suzuki, S.O.5
Masuda, K.6
Otera, H.7
Nakanishi, Y.8
Nonaka, I.9
Goto, Y.10
-
104
-
-
70349944660
-
The dynamin-related GTPase Drp1 is required for embryonic and brain development in mice
-
Wakabayashi, J.; Zhang, Z.; Wakabayashi, N.; Tamura, Y.; Fukaya, M.; Kensler, T.W.; Iijima, M.; Sesaki, H. The dynamin-related GTPase Drp1 is required for embryonic and brain development in mice. J. Cell Biol. 2009, 186, 805-816
-
(2009)
J. Cell Biol
, vol.186
, pp. 805-816
-
-
Wakabayashi, J.1
Zhang, Z.2
Wakabayashi, N.3
Tamura, Y.4
Fukaya, M.5
Kensler, T.W.6
Iijima, M.7
Sesaki, H.8
-
105
-
-
84908079648
-
Loss of mitochondrial fission depletes axonal mitochondria in midbrain dopamine neurons
-
Berthet, A.; Margolis, E.B.; Zhang, J.; Hsieh, I.; Zhang, J.; Hnasko, T.S.; Ahmad, J.; Edwards, R.H.; Sesaki, H.; Huang, E.J.; et al. Loss of mitochondrial fission depletes axonal mitochondria in midbrain dopamine neurons. J. Neurosci. 2014, 34, 14304-14317
-
(2014)
J. Neurosci
, vol.34
, pp. 14304-14317
-
-
Berthet, A.1
Margolis, E.B.2
Zhang, J.3
Hsieh, I.4
Zhang, J.5
Hnasko, T.S.6
Ahmad, J.7
Edwards, R.H.8
Sesaki, H.9
Huang, E.J.10
-
106
-
-
10744230149
-
The new mutation, E46K, of alpha-synuclein causes Parkinson and Lewy body dementia
-
Zarranz, J.J.; Alegre, J.; Gomez-Esteban, J.C.; Lezcano, E.; Ros, R.; Ampuero, I.; Vidal, L.; Hoenicka, J.; Rodriguez, O.; Atares, B.; et al. The new mutation, E46K, of alpha-synuclein causes Parkinson and Lewy body dementia. Ann. Neurol. 2004, 55, 164-173
-
(2004)
Ann. Neurol
, vol.55
, pp. 164-173
-
-
Zarranz, J.J.1
Alegre, J.2
Gomez-Esteban, J.C.3
Lezcano, E.4
Ros, R.5
Ampuero, I.6
Vidal, L.7
Hoenicka, J.8
Rodriguez, O.9
Atares, B.10
-
107
-
-
0142217556
-
DJ-1(PARK7), a novel gene for autosomal recessive, early onset parkinsonism
-
Bonifati, V.; Rizzu, P.; Squitieri, F.; Krieger, E.; Vanacore, N.; van Swieten, J.C.; Brice, A.; van Duijn, C.M.; Oostra, B.; Meco, G.; et al. DJ-1(PARK7), a novel gene for autosomal recessive, early onset parkinsonism. Neurol. Sci. 2003, 24, 159-160
-
(2003)
Neurol. Sci
, vol.24
, pp. 159-160
-
-
Bonifati, V.1
Rizzu, P.2
Squitieri, F.3
Krieger, E.4
Vanacore, N.5
Van Swieten, J.C.6
Brice, A.7
Van Duijn, C.M.8
Oostra, B.9
Meco, G.10
-
108
-
-
31544477143
-
Pathogenesis of Parkinson’s disease: Implications from familial Parkinson’s disease
-
Iwatsubo, T.; Ito, G.; Takatori, S.; Hannno, Y.; Kuwahara, T. Pathogenesis of Parkinson’s disease: Implications from familial Parkinson’s disease. Rinsho Shinkeigaku 2005, 45, 899-901
-
(2005)
Rinsho Shinkeigaku
, vol.45
, pp. 899-901
-
-
Iwatsubo, T.1
Ito, G.2
Takatori, S.3
Hannno, Y.4
Kuwahara, T.5
-
109
-
-
24944449513
-
Analysis of LRRK 2 G 2019 S and I 2020 T mutations in Parkinson’s disease
-
Bialecka, M.; Hui, S.; Klodowska-Duda, G.; Opala, G.; Tan, E.K.; Drozdzik, M. Analysis of LRRK 2 G 2019 S and I 2020 T mutations in Parkinson’s disease. Neurosci. Lett. 2005, 390, 1-3
-
(2005)
Neurosci. Lett.
, vol.390
, pp. 1-3
-
-
Bialecka, M.1
Hui, S.2
Klodowska-Duda, G.3
Opala, G.4
Tan, E.K.5
Drozdzik, M.6
-
110
-
-
0033862370
-
The aging process: Where are the drug opportunities
-
Smith, R.G. The aging process: Where are the drug opportunities? Curr. Opin. Chem. Biol. 2000, 4, 371-376
-
(2000)
Curr. Opin. Chem. Biol
, vol.4
, pp. 371-376
-
-
Smith, R.G.1
-
111
-
-
0032692692
-
Reduced Nurr1 expression increases the vulnerability of mesencephalic dopamine neurons to MPTP-induced injury
-
Le, W.; Conneely, O.M.; He, Y.; Jankovic, J.; Appel, S.H. Reduced Nurr1 expression increases the vulnerability of mesencephalic dopamine neurons to MPTP-induced injury. J. Neurochem. 1999, 73, 2218-2221
-
(1999)
J. Neurochem
, vol.73
, pp. 2218-2221
-
-
Le, W.1
Conneely, O.M.2
He, Y.3
Jankovic, J.4
Appel, S.H.5
-
112
-
-
0030572741
-
Distribution of messenger RNAs for the orphan nuclear receptors Nurr1 and Nur77 (NGFI-B) in adult rat brain using in situ hybridization
-
Xiao, Q.; Castillo, S.O.; Nikodem, V.M. Distribution of messenger RNAs for the orphan nuclear receptors Nurr1 and Nur77 (NGFI-B) in adult rat brain using in situ hybridization. Neuroscience 1996, 75, 221-230
-
(1996)
Neuroscience
, vol.75
, pp. 221-230
-
-
Xiao, Q.1
Castillo, S.O.2
Nikodem, V.M.3
-
113
-
-
77955029885
-
Effect of endogenous mutant and wild-type PINK1 on Parkin in fibroblasts from Parkinson disease patients
-
Rakovic, A.; Grunewald, A.; Seibler, P.; Ramirez, A.; Kock, N.; Orolicki, S.; Lohmann, K.; Klein, C. Effect of endogenous mutant and wild-type PINK1 on Parkin in fibroblasts from Parkinson disease patients. Hum. Mol. Genet. 2010, 19, 3124-3137
-
(2010)
Hum. Mol. Genet.
, vol.19
, pp. 3124-3137
-
-
Rakovic, A.1
Grunewald, A.2
Seibler, P.3
Ramirez, A.4
Kock, N.5
Orolicki, S.6
Lohmann, K.7
Klein, C.8
-
114
-
-
79952369437
-
Mutations in PINK1 and Parkin Impair Ubiquitination of Mitofusins in Human Fibroblasts
-
Rakovic, A.; Grunewald, A.; Kottwitz, J.; Bruggemann, N.; Pramstaller, P.P.; Lohmann, K.; Klein, C. Mutations in PINK1 and Parkin Impair Ubiquitination of Mitofusins in Human Fibroblasts. PLoS ONE 2011, 6, e16746
-
(2011)
Plos ONE
, vol.6
-
-
Rakovic, A.1
Grunewald, A.2
Kottwitz, J.3
Bruggemann, N.4
Pramstaller, P.P.5
Lohmann, K.6
Klein, C.7
-
115
-
-
84875435411
-
Tanshinone IIA and Cryptotanshinone Prevent Mitochondrial Dysfunction in Hypoxia-Induced H9c2 Cells: Association to Mitochondrial ROS, Intracellular Nitric Oxide, and Calcium Levels
-
Jin, H.J.; Li, C.G. Tanshinone IIA and Cryptotanshinone Prevent Mitochondrial Dysfunction in Hypoxia-Induced H9c2 Cells: Association to Mitochondrial ROS, Intracellular Nitric Oxide, and Calcium Levels. Evid. Based Complement. Alternat. Med. 2013, 2013, 610694
-
(2013)
Evid. Based Complement. Alternat. Med
, vol.2013
-
-
Jin, H.J.1
Li, C.G.2
-
116
-
-
39449088321
-
The PINK1/Parkin pathway regulates mitochondrial morphology
-
Poole, A.C.; Thomas, R.E.; Andrews, L.A.; McBride, H.M.; Whitworth, A.J.; Pallanck, L.J. The PINK1/Parkin pathway regulates mitochondrial morphology. Proc. Natl. Acad. Sci. USA 2008, 105, 1638-1643
-
(2008)
Proc. Natl. Acad. Sci. USA
, vol.105
, pp. 1638-1643
-
-
Poole, A.C.1
Thomas, R.E.2
Andrews, L.A.3
McBride, H.M.4
Whitworth, A.J.5
Pallanck, L.J.6
-
117
-
-
44349195101
-
Pink1 regulates mitochondrial dynamics through interaction with the fission/fusion machinery
-
Yang, Y.; Ouyang, Y.; Yang, L.; Beal, M.F.; McQuibban, A.; Vogel, H.; Lu, B. Pink1 regulates mitochondrial dynamics through interaction with the fission/fusion machinery. Proc. Natl. Acad. Sci. USA 2008, 105, 7070-7075
-
(2008)
Proc. Natl. Acad. Sci. USA
, vol.105
, pp. 7070-7075
-
-
Yang, Y.1
Ouyang, Y.2
Yang, L.3
Beal, M.F.4
McQuibban, A.5
Vogel, H.6
Lu, B.7
-
118
-
-
79960826207
-
The PINK1/Parkin pathway regulates mitochondrial dynamics and function in mammalian hippocampal and dopaminergic neurons. Hum. Mol
-
Yu, W.; Sun, Y.; Guo, S.; Lu, B. The PINK1/Parkin pathway regulates mitochondrial dynamics and function in mammalian hippocampal and dopaminergic neurons. Hum. Mol. Genet. 2011, 20, 3227-3240
-
(2011)
Genet
, vol.20
, pp. 3227-3240
-
-
Yu, W.1
Sun, Y.2
Guo, S.3
Lu, B.4
-
119
-
-
84860539187
-
Parkinson’s disease-associated DJ-1 mutations impair mitochondrial dynamics and cause mitochondrial dysfunction
-
Wang, X.; Petrie, T.G.; Liu, Y.; Liu, J.; Fujioka, H.; Zhu, X. Parkinson’s disease-associated DJ-1 mutations impair mitochondrial dynamics and cause mitochondrial dysfunction. J. Neurochem. 2012, 121, 830-839
-
(2012)
J. Neurochem
, vol.121
, pp. 830-839
-
-
Wang, X.1
Petrie, T.G.2
Liu, Y.3
Liu, J.4
Fujioka, H.5
Zhu, X.6
-
120
-
-
84925298301
-
Mitochondrial dysfunction and mitophagy in Parkinson’s: From familial to sporadic disease
-
Ryan, B.J.; Hoek, S.; Fon, E.A.; Wade-Martins, R. Mitochondrial dysfunction and mitophagy in Parkinson’s: From familial to sporadic disease. Trends Biochem. Sci. 2015, 40, 200-210
-
(2015)
Trends Biochem. Sci
, vol.40
, pp. 200-210
-
-
Ryan, B.J.1
Hoek, S.2
Fon, E.A.3
Wade-Martins, R.4
-
121
-
-
84863728713
-
Leucine-rich repeat kinase 2 disturbs mitochondrial dynamics via Dynamin-like protein
-
Niu, J.; Yu, M.; Wang, C.; Xu, Z. Leucine-rich repeat kinase 2 disturbs mitochondrial dynamics via Dynamin-like protein. J. Neurochem. 2012, 122, 650-658
-
(2012)
J. Neurochem
, vol.122
, pp. 650-658
-
-
Niu, J.1
Yu, M.2
Wang, C.3
Xu, Z.4
-
122
-
-
84859259002
-
LRRK2 regulates mitochondrial dynamics and function through direct interaction with DLP1
-
Wang, X.; Yan, M.H.; Fujioka, H.; Liu, J.; Wilson-Delfosse, A.; Chen, S.G.; Perry, G.; Casadesus, G.; Zhu, X. LRRK2 regulates mitochondrial dynamics and function through direct interaction with DLP1. Hum. Mol. Genet. 2012, 21, 1931-1944
-
(2012)
Hum. Mol. Genet
, vol.21
, pp. 1931-1944
-
-
Wang, X.1
Yan, M.H.2
Fujioka, H.3
Liu, J.4
Wilson-Delfosse, A.5
Chen, S.G.6
Perry, G.7
Casadesus, G.8
Zhu, X.9
-
123
-
-
84887004639
-
Inhibition of excessive mitochondrial fission reduced aberrant autophagy and neuronal damage caused by LRRK2 G2019S mutation
-
Su, Y.C.; Qi, X. Inhibition of excessive mitochondrial fission reduced aberrant autophagy and neuronal damage caused by LRRK2 G2019S mutation. Hum. Mol. Genet. 2013, 22, 4545-4561
-
(2013)
Hum. Mol. Genet.
, vol.22
, pp. 4545-4561
-
-
Su, Y.C.1
Qi, X.2
-
124
-
-
84890096545
-
Inhibition of mitochondrial fragmentation diminishes Huntington’s disease-associated neurodegeneration
-
Guo, X.; Disatnik, M.H.; Monbureau, M.; Shamloo, M.; Mochly-Rosen, D.; Qi, X. Inhibition of mitochondrial fragmentation diminishes Huntington’s disease-associated neurodegeneration. J. Clin. Investig. 2013, 123, 5371-5388
-
(2013)
J. Clin. Investig
, vol.123
, pp. 5371-5388
-
-
Guo, X.1
Disatnik, M.H.2
Monbureau, M.3
Shamloo, M.4
Mochly-Rosen, D.5
Qi, X.6
-
125
-
-
84876312885
-
A novel Drp1 inhibitor diminishes aberrant mitochondrial fission and neurotoxicity
-
Qi, X.; Qvit, N.; Su, Y.C.; Mochly-Rosen, D. A novel Drp1 inhibitor diminishes aberrant mitochondrial fission and neurotoxicity. J. Cell Sci. 2013, 126, 789-802
-
(2013)
J. Cell Sci
, vol.126
, pp. 789-802
-
-
Qi, X.1
Qvit, N.2
Su, Y.C.3
Mochly-Rosen, D.4
-
126
-
-
84904700068
-
Autophagy and its normal and pathogenic states in the brain. Annu
-
Yamamoto, A.; Yue, Z. Autophagy and its normal and pathogenic states in the brain. Annu. Rev. Neurosci. 2014, 37, 55-78
-
(2014)
Rev. Neurosci
, vol.37
, pp. 55-78
-
-
Yamamoto, A.1
Yue, Z.2
-
127
-
-
84901768886
-
Mitophagy mechanisms and role in human diseases
-
Redmann, M.; Dodson, M.; Boyer-Guittaut, M.; Darley-Usmar, V.; Zhang, J. Mitophagy mechanisms and role in human diseases. Int. J. Biochem. Cell Biol. 2014, 53, 127-33
-
(2014)
Int. J. Biochem. Cell Biol
, vol.53
, pp. 127-133
-
-
Redmann, M.1
Dodson, M.2
Boyer-Guittaut, M.3
Darley-Usmar, V.4
Zhang, J.5
-
128
-
-
33846196301
-
Identification of essential residues for the C-terminal cleavage of the mammalian LC3: A lesson from yeast Atg8
-
Fass, E.; Amar, N.; Elazar, Z. Identification of essential residues for the C-terminal cleavage of the mammalian LC3: A lesson from yeast Atg8. Autophagy 2007, 3, 48-50
-
(2007)
Autophagy
, vol.3
, pp. 48-50
-
-
Fass, E.1
Amar, N.2
Elazar, Z.3
-
129
-
-
0034329418
-
LC3, a mammalian homologue of yeast Apg8p, is localized in autophagosome membranes after processing
-
Kabeya, Y.; Mizushima, N.; Ueno, T.; Yamamoto, A.; Kirisako, T.; Noda, T.; Kominami, E.; Ohsumi, Y.; Yoshimori, T. LC3, a mammalian homologue of yeast Apg8p, is localized in autophagosome membranes after processing. EMBO J. 2000, 19, 5720-5728
-
(2000)
EMBO J
, vol.19
, pp. 5720-5728
-
-
Kabeya, Y.1
Mizushima, N.2
Ueno, T.3
Yamamoto, A.4
Kirisako, T.5
Noda, T.6
Kominami, E.7
Ohsumi, Y.8
Yoshimori, T.9
-
130
-
-
67650264633
-
Atg32 is a mitochondrial protein that confers selectivity during mitophagy
-
Kanki, T.; Wang, K.; Cao, Y.; Baba, M.; Klionsky, D.J. Atg32 is a mitochondrial protein that confers selectivity during mitophagy. Dev. Cell 2009, 17, 98-109
-
(2009)
Dev. Cell
, vol.17
, pp. 98-109
-
-
Kanki, T.1
Wang, K.2
Cao, Y.3
Baba, M.4
Klionsky, D.J.5
-
131
-
-
67650246357
-
Mitochondria-anchored receptor Atg32 mediates degradation of mitochondria via selective autophagy
-
Okamoto, K.; Kondo-Okamoto, N.; Ohsumi, Y. Mitochondria-anchored receptor Atg32 mediates degradation of mitochondria via selective autophagy. Dev. Cell 2009, 17, 87-97
-
(2009)
Dev. Cell
, vol.17
, pp. 87-97
-
-
Okamoto, K.1
Kondo-Okamoto, N.2
Ohsumi, Y.3
-
132
-
-
84862789618
-
Mitochondrial outer-membrane protein FUNDC1 mediates hypoxia-induced mitophagy in mammalian cells
-
Liu, L.; Feng, D.; Chen, G.; Chen, M.; Zheng, Q.; Song, P.; Ma, Q.; Zhu, C.; Wang, R.; Qi, W.; et al. Mitochondrial outer-membrane protein FUNDC1 mediates hypoxia-induced mitophagy in mammalian cells. Nat. Cell Biol. 2012, 14, 177-185
-
(2012)
Nat. Cell Biol
, vol.14
, pp. 177-185
-
-
Liu, L.1
Feng, D.2
Chen, G.3
Chen, M.4
Zheng, Q.5
Song, P.6
Ma, Q.7
Zhu, C.8
Wang, R.9
Qi, W.10
-
133
-
-
78649300971
-
P62/SQSTM1 is required for Parkin-induced mitochondrial clustering but not mitophagy; VDAC1 is dispensable for both
-
Narendra, D.; Kane, L.A.; Hauser, D.N.; Fearnley, I.M.; Youle, R.J. p62/SQSTM1 is required for Parkin-induced mitochondrial clustering but not mitophagy; VDAC1 is dispensable for both. Autophagy 2010, 6, 1090-1106
-
(2010)
Autophagy
, vol.6
, pp. 1090-1106
-
-
Narendra, D.1
Kane, L.A.2
Hauser, D.N.3
Fearnley, I.M.4
Youle, R.J.5
-
134
-
-
84911988907
-
BNIP3 interacting with LC3 triggers excessive mitophagy in delayed neuronal death in stroke
-
Shi, R.Y.; Zhu, S.H.; Li, V.; Gibson, S.B.; Xu, X.S.; Kong, J.M. BNIP3 interacting with LC3 triggers excessive mitophagy in delayed neuronal death in stroke. CNS Neurosci. Ther. 2014, 20, 1045-1055
-
(2014)
CNS Neurosci. Ther
, vol.20
, pp. 1045-1055
-
-
Shi, R.Y.1
Zhu, S.H.2
Li, V.3
Gibson, S.B.4
Xu, X.S.5
Kong, J.M.6
-
135
-
-
84922506220
-
AMBRA1 is able to induce mitophagy via LC3 binding, regardless of PARKIN and p62/SQSTM1. Cell
-
Strappazzon, F.; Nazio, F.; Corrado, M.; Cianfanelli, V.; Romagnoli, A.; Fimia, G.M.; Campello, S.; Nardacci, R.; Piacentini, M.; Campanella, M.; et al. AMBRA1 is able to induce mitophagy via LC3 binding, regardless of PARKIN and p62/SQSTM1. Cell. Death Differ. 2015, 22, 419-432
-
(2015)
Death Differ
, vol.22
, pp. 419-432
-
-
Strappazzon, F.1
Nazio, F.2
Corrado, M.3
Cianfanelli, V.4
Romagnoli, A.5
Fimia, G.M.6
Campello, S.7
Nardacci, R.8
Piacentini, M.9
Campanella, M.10
-
136
-
-
79952355107
-
Selective autophagy mediated by autophagic adapter proteins
-
Johansen, T.; Lamark, T. Selective autophagy mediated by autophagic adapter proteins. Autophagy 2011, 7, 279-296
-
(2011)
Autophagy
, vol.7
, pp. 279-296
-
-
Johansen, T.1
Lamark, T.2
-
137
-
-
84913570274
-
Rotenone impairs autophagic flux and lysosomal functions in Parkinson’s disease
-
Wu, F.; Xu, H.D.; Guan, J.J.; Hou, Y.S.; Gu, J.H.; Zhen, X.C., Qin, Z.H. Rotenone impairs autophagic flux and lysosomal functions in Parkinson’s disease. Neuroscience 2015, 284, 900-911
-
(2015)
Neuroscience
, vol.284
, pp. 900-911
-
-
Wu, F.1
Xu, H.D.2
Guan, J.J.3
Hou, Y.S.4
Gu, J.H.5
Zhen, X.C.6
Qin, Z.H.7
-
138
-
-
84865550601
-
Autophagy-dependent and-independent involvement of AMP-activated protein kinase in 6-hydroxydopamine toxicity to SH-SY5Y neuroblastoma cells
-
Arsikin, K.; Kravic-Stevovic, T.; Jovanovic, M.; Ristic, B.; Tovilovic, G.; Zogovic, N.; Bumbasirevic, V.; Trajkovic, V.; Harhaji-Trajkovic, L. Autophagy-dependent and-independent involvement of AMP-activated protein kinase in 6-hydroxydopamine toxicity to SH-SY5Y neuroblastoma cells. Biochim. Biophys. Acta 2012, 1822, 1826-1836
-
(2012)
Biochim. Biophys. Acta
, vol.1822
, pp. 1826-1836
-
-
Arsikin, K.1
Kravic-Stevovic, T.2
Jovanovic, M.3
Ristic, B.4
Tovilovic, G.5
Zogovic, N.6
Bumbasirevic, V.7
Trajkovic, V.8
Harhaji-Trajkovic, L.9
-
140
-
-
79954577302
-
Targeting mitochondrial dysfunction: Role for PINK1 and Parkin in mitochondrial quality control
-
Narendra, D.P.; Youle, R.J. Targeting mitochondrial dysfunction: Role for PINK1 and Parkin in mitochondrial quality control. Antioxid. Redox Signal. 2011, 14, 1929-1938
-
(2011)
Antioxid. Redox Signal
, vol.14
, pp. 1929-1938
-
-
Narendra, D.P.1
Youle, R.J.2
-
141
-
-
84906861963
-
Mitophagy of damaged mitochondria occurs locally in distal neuronal axons and requires PINK1 and Parkin
-
Ashrafi, G.; Schlehe, J.S.; LaVoie, M.J.; Schwarz, T.L. Mitophagy of damaged mitochondria occurs locally in distal neuronal axons and requires PINK1 and Parkin. J. Cell Biol. 2014, 206, 655-670
-
(2014)
J. Cell Biol
, vol.206
, pp. 655-670
-
-
Ashrafi, G.1
Schlehe, J.S.2
Lavoie, M.J.3
Schwarz, T.L.4
-
142
-
-
75949130828
-
PINK1/Parkin-mediated mitophagy is dependent on VDAC1 and p62/SQSTM1. Nat
-
Geisler, S.; Holmstrom, K.M.; Skujat, D.; Fiesel, F.C.; Rothfuss, O.C.; Kahle, P.J.; Springer, W. PINK1/Parkin-mediated mitophagy is dependent on VDAC1 and p62/SQSTM1. Nat. Cell Biol. 2010, 12, 119-131
-
(2010)
Cell Biol
, vol.12
, pp. 119-131
-
-
Geisler, S.1
Holmstrom, K.M.2
Skujat, D.3
Fiesel, F.C.4
Rothfuss, O.C.5
Kahle, P.J.6
Springer, W.7
-
143
-
-
84873843566
-
Phosphatase and tensin homolog (PTEN)-induced putative kinase 1 (PINK1)-dependent ubiquitination of endogenous Parkin attenuates mitophagy: Study in human primary fibroblasts and induced pluripotent stem cell-derived neurons
-
Rakovic, A.; Shurkewitsch, K.; Seibler, P.; Grunewald, A.; Zanon, A.; Hagenah, J.; Krainc, D.; Klein, C. Phosphatase and tensin homolog (PTEN)-induced putative kinase 1 (PINK1)-dependent ubiquitination of endogenous Parkin attenuates mitophagy: Study in human primary fibroblasts and induced pluripotent stem cell-derived neurons. J. Biol. Chem. 2013, 288, 2223-2237
-
(2013)
J. Biol. Chem
, vol.288
, pp. 2223-2237
-
-
Rakovic, A.1
Shurkewitsch, K.2
Seibler, P.3
Grunewald, A.4
Zanon, A.5
Hagenah, J.6
Krainc, D.7
Klein, C.8
-
144
-
-
79955701611
-
DJ-1 regulation of mitochondrial function and autophagy through oxidative stress
-
McCoy, M.K.; Cookson, M.R. DJ-1 regulation of mitochondrial function and autophagy through oxidative stress. Autophagy 2011, 7, 531-532
-
(2011)
Autophagy
, vol.7
, pp. 531-532
-
-
McCoy, M.K.1
Cookson, M.R.2
-
145
-
-
79956323688
-
DJ-1 acts in parallel to the PINK1/parkin pathway to control mitochondrial function and autophagy
-
Thomas, K.J.; McCoy, M.K.; Blackinton, J.; Beilina, A.; van der Brug, M.; Sandebring, A.; Miller, D.; Maric, D.; Cedazo-Minguez, A.; Cookson, M.R. DJ-1 acts in parallel to the PINK1/parkin pathway to control mitochondrial function and autophagy. Hum. Mol. Genet. 2011, 20, 40-50
-
(2011)
Hum. Mol. Genet
, vol.20
, pp. 40-50
-
-
Thomas, K.J.1
McCoy, M.K.2
Blackinton, J.3
Beilina, A.4
Van Der Brug, M.5
Sandebring, A.6
Miller, D.7
Maric, D.8
Cedazo-Minguez, A.9
Cookson, M.R.10
-
146
-
-
77956522541
-
Loss of the Parkinson’s disease-linked gene DJ-1 perturbs mitochondrial dynamics
-
Irrcher, I.; Aleyasin, H.; Seifert, E.L.; Hewitt, S.J.; Chhabra, S.; Phillips, M.; Lutz, A.K.; Rousseaux, M.W.; Bevilacqua, L.; Jahani-Asl, A.; et al. Loss of the Parkinson’s disease-linked gene DJ-1 perturbs mitochondrial dynamics. Hum. Mol. Genet. 2010, 19, 3734-46
-
(2010)
Hum. Mol. Genet.
, vol.19
, pp. 3734-3746
-
-
Irrcher, I.1
Aleyasin, H.2
Seifert, E.L.3
Hewitt, S.J.4
Chhabra, S.5
Phillips, M.6
Lutz, A.K.7
Rousseaux, M.W.8
Bevilacqua, L.9
Jahani-Asl, A.10
-
147
-
-
33744760852
-
Association of PINK1 and DJ-1 confers digenic inheritance of early-onset Parkinson’s disease
-
Tang, B.; Xiong, H.; Sun, P.; Zhang, Y.; Wang, D.; Hu, Z.; Zhu, Z.; Ma, H.; Pan, Q.; Xia, J.H.; et al. Association of PINK1 and DJ-1 confers digenic inheritance of early-onset Parkinson’s disease. Hum. Mol. Genet. 2006, 15, 1816-1825
-
(2006)
Hum. Mol. Genet.
, vol.15
, pp. 1816-1825
-
-
Tang, B.1
Xiong, H.2
Sun, P.3
Zhang, Y.4
Wang, D.5
Hu, Z.6
Zhu, Z.7
Ma, H.8
Pan, Q.9
Xia, J.H.10
-
148
-
-
65649118917
-
Parkin, PINK1, and DJ-1 form a ubiquitin E3 ligase complex promoting unfolded protein degradation
-
Xiong, H.; Wang, D.; Chen, L.; Choo, Y.S.; Ma, H.; Tang, C.; Xia, K.; Jiang, W.; Ronai, Z.; Zhuang, X.; et al. Parkin, PINK1, and DJ-1 form a ubiquitin E3 ligase complex promoting unfolded protein degradation. J. Clin. Investig. 2009, 119, 650-660
-
(2009)
J. Clin. Investig.
, vol.119
, pp. 650-660
-
-
Xiong, H.1
Wang, D.2
Chen, L.3
Choo, Y.S.4
Ma, H.5
Tang, C.6
Xia, K.7
Jiang, W.8
Ronai, Z.9
Zhuang, X.10
-
149
-
-
39549117093
-
Role of autophagy in G2019S-LRRK2-associated neurite shortening in differentiated SH-SY5Y cells
-
Plowey, E.D.; Cherra, S.J., 3rd; Liu, Y.J.; Chu, C.T. Role of autophagy in G2019S-LRRK2-associated neurite shortening in differentiated SH-SY5Y cells. J. Neurochem. 2008, 105, 1048-1056
-
(2008)
J. Neurochem
, vol.105
, pp. 1048-1056
-
-
Plowey, E.D.1
Cherra, S.J.2
Liu, Y.J.3
Chu, C.T.4
-
150
-
-
84904400238
-
G2019S LRRK2 mutant fibroblasts from Parkinson’s disease patients show increased sensitivity to neurotoxin 1-methyl-4-phenylpyridinium dependent of autophagy
-
Yakhine-Diop, S.M.; Bravo-San Pedro, J.M.; Gomez-Sanchez, R.; Pizarro-Estrella, E.; Rodriguez-Arribas, M.; Climent, V.; Aiastui, A.; Lopez de Munain, A.; Fuentes, J.M.; Gonzalez-Polo, R.A. G2019S LRRK2 mutant fibroblasts from Parkinson’s disease patients show increased sensitivity to neurotoxin 1-methyl-4-phenylpyridinium dependent of autophagy. Toxicology 2014, 324, 1-9
-
(2014)
Toxicology
, vol.324
, pp. 1-9
-
-
Yakhine-Diop, S.M.1
Bravo-San Pedro, J.M.2
Gomez-Sanchez, R.3
Pizarro-Estrella, E.4
Rodriguez-Arribas, M.5
Climent, V.6
Aiastui, A.7
De Lopez Munain, A.8
Fuentes, J.M.9
Gonzalez-Polo, R.A.10
-
151
-
-
84860510280
-
Disease-specific phenotypes in dopamine neurons from human iPS-based models of genetic and sporadic Parkinson’s disease
-
Sanchez-Danes, A.; Richaud-Patin, Y.; Carballo-Carbajal, I.; Jimenez-Delgado, S.; Caig, C.; Mora, S.; di Guglielmo, C.; Ezquerra, M.; Patel, B.; Giralt, A.; et al. Disease-specific phenotypes in dopamine neurons from human iPS-based models of genetic and sporadic Parkinson’s disease. EMBO Mol. Med. 2012, 4, 380-395
-
(2012)
EMBO Mol. Med
, vol.4
, pp. 380-395
-
-
Sanchez-Danes, A.1
Richaud-Patin, Y.2
Carballo-Carbajal, I.3
Jimenez-Delgado, S.4
Caig, C.5
Mora, S.6
Di Guglielmo, C.7
Ezquerra, M.8
Patel, B.9
Giralt, A.10
-
152
-
-
84870903681
-
Genetic animal models for evaluating the role of autophagy in etiopathogenesis of Parkinson disease
-
Lachenmayer, M.L.; Yue, Z. Genetic animal models for evaluating the role of autophagy in etiopathogenesis of Parkinson disease. Autophagy 2012, 8, 1837-1838
-
(2012)
Autophagy
, vol.8
, pp. 1837-1838
-
-
Lachenmayer, M.L.1
Yue, Z.2
-
153
-
-
70349991886
-
LRRK2 regulates autophagic activity and localizes to specific membrane microdomains in a novel human genomic reporter cellular model
-
Alegre-Abarrategui, J.; Christian, H.; Lufino, M.M.; Mutihac, R.; Venda, L.L.; Ansorge, O.; Wade-Martins, R. LRRK2 regulates autophagic activity and localizes to specific membrane microdomains in a novel human genomic reporter cellular model. Hum. Mol. Genet. 2009, 18, 4022-4034
-
(2009)
Hum. Mol. Genet
, vol.18
, pp. 4022-4034
-
-
Alegre-Abarrategui, J.1
Christian, H.2
Lufino, M.M.3
Mutihac, R.4
Venda, L.L.5
Ansorge, O.6
Wade-Martins, R.7
-
154
-
-
84906850990
-
The LRRK2 inhibitor GSK2578215A induces protective autophagy in SH-SY5Y cells: Involvement of Drp-1-mediated mitochondrial fission and mitochondrial-derived ROS signaling
-
Saez-Atienzar, S.; Bonet-Ponce, L.; Blesa, J.R.; Romero, F.J.; Murphy, M.P.; Jordan, J.; Galindo, M.F. The LRRK2 inhibitor GSK2578215A induces protective autophagy in SH-SY5Y cells: Involvement of Drp-1-mediated mitochondrial fission and mitochondrial-derived ROS signaling. Cell Death Dis. 2014, 5, e1368
-
(2014)
Cell Death Dis
, vol.5
-
-
Saez-Atienzar, S.1
Bonet-Ponce, L.2
Blesa, J.R.3
Romero, F.J.4
Murphy, M.P.5
Jordan, J.6
Galindo, M.F.7
-
155
-
-
84862907943
-
Leucinerich repeat kinase 2 regulates autophagy through a calcium-dependent pathway involving NAADP
-
Gomez-Suaga, P.; Luzon-Toro, B.; Churamani, D.; Zhang, L.; Bloor-Young, D.; Patel, S.; Woodman, P.G.; Churchill, G.C.; Hilfiker, S. Leucinerich repeat kinase 2 regulates autophagy through a calcium-dependent pathway involving NAADP. Hum. Mol. Genet. 2012, 21, 511-525
-
(2012)
Hum. Mol. Genet
, vol.21
, pp. 511-525
-
-
Gomez-Suaga, P.1
Luzon-Toro, B.2
Churamani, D.3
Zhang, L.4
Bloor-Young, D.5
Patel, S.6
Woodman, P.G.7
Churchill, G.C.8
Hilfiker, S.9
-
156
-
-
84872362045
-
The LRRK2 G2019S mutant exacerbates basal autophagy through activation of the MEK/ERK pathway
-
Bravo-San Pedro, J.M.; Niso-Santano, M.; Gomez-Sanchez, R.; Pizarro-Estrella, E.; Aiastui-Pujana, A.; Gorostidi, A.; Climent, V.; Lopez de Maturana, R.; Sanchez-Pernaute, R.; Lopez de Munain, A.; et al. The LRRK2 G2019S mutant exacerbates basal autophagy through activation of the MEK/ERK pathway. Cell. Mol. Life Sci. 2013, 70, 121-136
-
(2013)
Cell. Mol. Life Sci.
, vol.70
, pp. 121-136
-
-
Bravo-San Pedro, J.M.1
Niso-Santano, M.2
Gomez-Sanchez, R.3
Pizarro-Estrella, E.4
Aiastui-Pujana, A.5
Gorostidi, A.6
Climent, V.7
De Lopez Maturana, R.8
Sanchez-Pernaute, R.9
De Lopez Munain, A.10
-
157
-
-
84862301071
-
LRRK2 as a modulator of lysosomal calcium homeostasis with downstream effects on autophagy
-
Gomez-Suaga, P.; Hilfiker, S. LRRK2 as a modulator of lysosomal calcium homeostasis with downstream effects on autophagy. Autophagy 2012, 8, 692-693
-
(2012)
Autophagy
, vol.8
, pp. 692-693
-
-
Gomez-Suaga, P.1
Hilfiker, S.2
-
158
-
-
84875640261
-
Interplay of LRRK2 with chaperone-mediated autophagy
-
Orenstein, S.J.; Kuo, S.H.; Tasset, I.; Arias, E.; Koga, H.; Fernandez-Carasa, I.; Cortes, E.; Honig, L.S.; Dauer, W.; Consiglio, A.; et al. Interplay of LRRK2 with chaperone-mediated autophagy. Nat. Neurosci. 2013, 16, 394-406
-
(2013)
Nat. Neurosci
, vol.16
, pp. 394-406
-
-
Orenstein, S.J.1
Kuo, S.H.2
Tasset, I.3
Arias, E.4
Koga, H.5
Fernandez-Carasa, I.6
Cortes, E.7
Honig, L.S.8
Dauer, W.9
Consiglio, A.10
-
159
-
-
84912122968
-
Threonine 56 phosphorylation of Bcl-2 is required for LRRK2 G2019S-induced mitochondrial depolarization and autophagy
-
Su, Y.C.; Guo, X.; Qi, X. Threonine 56 phosphorylation of Bcl-2 is required for LRRK2 G2019S-induced mitochondrial depolarization and autophagy. Biochim. Biophys. Acta 2015, 1852, 12-21
-
(1852)
Biochim. Biophys. Acta
, vol.2015
, pp. 12-21
-
-
Su, Y.C.1
Guo, X.2
Qi, X.3
-
160
-
-
0022515585
-
Uptake of the neurotoxin 1-methyl-4-phenylpyridine (MPP+) by mitochondria and its relation to the inhibition of the mitochondrial oxidation of NAD+-linked substrates by MPP+. Biochem. Biophys. Res
-
Ramsay, R.R.; Salach, J.I.; Singer, T.P. Uptake of the neurotoxin 1-methyl-4-phenylpyridine (MPP+) by mitochondria and its relation to the inhibition of the mitochondrial oxidation of NAD+-linked substrates by MPP+. Biochem. Biophys. Res. Commun. 1986, 134, 743-748
-
(1986)
Commun
, vol.134
, pp. 743-748
-
-
Ramsay, R.R.1
Salach, J.I.2
Singer, T.P.3
-
161
-
-
0027304231
-
The high sensitivity to rotenone of striatal dopamine uptake suggests the existence of a constitutive metabolic deficiency in dopaminergic neurons from the substantia nigra
-
Marey-Semper, I.; Gelman, M.; Levi-Strauss, M. The high sensitivity to rotenone of striatal dopamine uptake suggests the existence of a constitutive metabolic deficiency in dopaminergic neurons from the substantia nigra. Eur. J. Neurosci. 1993, 5, 1029-1034
-
(1993)
Eur. J. Neurosci
, vol.5
, pp. 1029-1034
-
-
Marey-Semper, I.1
Gelman, M.2
Levi-Strauss, M.3
-
162
-
-
78049383132
-
Mitochondrial alpha-synuclein accumulation impairs complex I function in dopaminergic neurons and results in increased mitophagy in vivo. Neurosci
-
Chinta, S.J.; Mallajosyula, J.K.; Rane, A.; Andersen, J.K. Mitochondrial alpha-synuclein accumulation impairs complex I function in dopaminergic neurons and results in increased mitophagy in vivo. Neurosci. Lett. 2010, 486, 235-239
-
(2010)
Lett
, vol.486
, pp. 235-239
-
-
Chinta, S.J.1
Mallajosyula, J.K.2
Rane, A.3
Andersen, J.K.4
-
163
-
-
44049099669
-
Mitochondrial import and accumulation of alpha-synuclein impair complex I in human dopaminergic neuronal cultures and Parkinson disease brain
-
Devi, L.; Raghavendran, V.; Prabhu, B.M.; Avadhani, N.G.; Anandatheerthavarada, H.K. Mitochondrial import and accumulation of alpha-synuclein impair complex I in human dopaminergic neuronal cultures and Parkinson disease brain. J. Biol. Chem. 2008, 283, 9089-9100
-
(2008)
J. Biol. Chem
, vol.283
, pp. 9089-9100
-
-
Devi, L.1
Raghavendran, V.2
Prabhu, B.M.3
Avadhani, N.G.4
Anandatheerthavarada, H.K.5
-
164
-
-
30644471051
-
Parkinson’s disease alpha-synuclein transgenic mice develop neuronal mitochondrial degeneration and cell death
-
Martin, L.J.; Pan, Y.; Price, A.C.; Sterling, W.; Copeland, N.G.; Jenkins, N.A.; Price, D.L.; Lee, M.K. Parkinson’s disease alpha-synuclein transgenic mice develop neuronal mitochondrial degeneration and cell death. J. Neurosci. 2006, 26, 41-50
-
(2006)
J. Neurosci
, vol.26
, pp. 41-50
-
-
Martin, L.J.1
Pan, Y.2
Price, A.C.3
Sterling, W.4
Copeland, N.G.5
Jenkins, N.A.6
Price, D.L.7
Lee, M.K.8
-
165
-
-
84885388816
-
The impact of reactive oxygen species and genetic mitochondrial mutations in Parkinson’s disease
-
Zuo, L.; Motherwell, M.S. The impact of reactive oxygen species and genetic mitochondrial mutations in Parkinson’s disease. Gene 2013, 532, 18-23
-
(2013)
Gene
, vol.532
, pp. 18-23
-
-
Zuo, L.1
Motherwell, M.S.2
-
166
-
-
84925725817
-
Aberrant protein S-nitrosylation contributes to the pathophysiology of neurodegenerative diseases
-
Nakamura, T.; Prikhodko, O.A.; Pirie, E.; Nagar, S.; Akhtar, M.W.; Oh, C.K.; McKercher, S.R.; Ambasudhan, R.; Okamoto, S.I.; Lipton, S.A. Aberrant protein S-nitrosylation contributes to the pathophysiology of neurodegenerative diseases. Neurobiol. Dis. 2015, doi:10.1016/j.nbd.2015.03.017
-
(2015)
Neurobiol. Dis
-
-
Nakamura, T.1
Prikhodko, O.A.2
Pirie, E.3
Nagar, S.4
Akhtar, M.W.5
Oh, C.K.6
McKercher, S.R.7
Ambasudhan, R.8
Okamoto, S.I.9
Lipton, S.A.10
-
167
-
-
0028625524
-
Identification of NO-producing and-receptive cells in mesencephalic transplants in a rat model of Parkinson’s disease: A study using NADPH-d enzyme-and NOSc/cGMP immunocytochemistry
-
Van Muiswinkel, F.L.; Steinbusch, H.W.; Drukarch, B.; de Vente, J. Identification of NO-producing and-receptive cells in mesencephalic transplants in a rat model of Parkinson’s disease: A study using NADPH-d enzyme-and NOSc/cGMP immunocytochemistry. Ann. N. Y. Acad. Sci. 1994, 738, 289-304
-
(1994)
Ann. N. Y. Acad. Sci
, vol.738
, pp. 289-304
-
-
Van Muiswinkel, F.L.1
Steinbusch, H.W.2
Drukarch, B.3
De Vente, J.4
-
168
-
-
77955085868
-
Redox reactions induced by nitrosative stress mediate protein misfolding and mitochondrial dysfunction in neurodegenerative diseases
-
Gu, Z.; Nakamura, T.; Lipton, S.A. Redox reactions induced by nitrosative stress mediate protein misfolding and mitochondrial dysfunction in neurodegenerative diseases. Mol. Neurobiol. 2010, 41, 55-72
-
(2010)
Mol. Neurobiol
, vol.41
, pp. 55-72
-
-
Gu, Z.1
Nakamura, T.2
Lipton, S.A.3
-
169
-
-
12244299912
-
Association between Parkinson’s disease and polymorphisms in the nNOS and iNOS genes in a community-based case-control study
-
Levecque, C.; Elbaz, A.; Clavel, J.; Richard, F.; Vidal, J.S.; Amouyel, P.; Tzourio, C.; Alperovitch, A.; Chartier-Harlin, M.C. Association between Parkinson’s disease and polymorphisms in the nNOS and iNOS genes in a community-based case-control study. Hum. Mol. Genet. 2003, 12, 79-86
-
(2003)
Hum. Mol. Genet
, vol.12
, pp. 79-86
-
-
Levecque, C.1
Elbaz, A.2
Clavel, J.3
Richard, F.4
Vidal, J.S.5
Amouyel, P.6
Tzourio, C.7
Alperovitch, A.8
Chartier-Harlin, M.C.9
-
170
-
-
61549143699
-
Age-and sex-differences in the nitric oxide synthase expression and dopamine concentration in the murine model of Parkinson’s disease induced by 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine
-
Joniec, I.; Ciesielska, A.; Kurkowska-Jastrzebska, I.; Przybylkowski, A.; Czlonkowska, A.; Czlonkowski, A. Age-and sex-differences in the nitric oxide synthase expression and dopamine concentration in the murine model of Parkinson’s disease induced by 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine. Brain Res. 2009, 1261, 7-19
-
(2009)
Brain Res
, vol.1261
, pp. 7-19
-
-
Joniec, I.1
Ciesielska, A.2
Kurkowska-Jastrzebska, I.3
Przybylkowski, A.4
Czlonkowska, A.5
Czlonkowski, A.6
-
171
-
-
39149086019
-
Protective action of neuronal nitric oxide synthase inhibitor in the MPTP mouse model of Parkinson’s disease. Metab
-
Watanabe, Y.; Kato, H.; Araki, T. Protective action of neuronal nitric oxide synthase inhibitor in the MPTP mouse model of Parkinson’s disease. Metab. Brain Dis. 2008, 23, 51-69
-
(2008)
Brain Dis
, vol.23
, pp. 51-69
-
-
Watanabe, Y.1
Kato, H.2
Araki, T.3
-
172
-
-
0033499335
-
Neuroprotection by (R)-deprenyl and 7-nitroindazole in the MPTP C57BL/6 mouse model of neurotoxicity
-
Castagnoli, K.; Palmer, S.; Castagnoli, N., Jr. Neuroprotection by (R)-deprenyl and 7-nitroindazole in the MPTP C57BL/6 mouse model of neurotoxicity. Neurobiology (Bp) 1999, 7, 135-149
-
(1999)
Neurobiology (Bp)
, vol.7
, pp. 135-149
-
-
Castagnoli, K.1
Palmer, S.2
Castagnoli, N.3
-
173
-
-
33746575844
-
Evolution of the molecular machines for protein import into mitochondria
-
Dolezal, P.; Likic, V.; Tachezy, J.; Lithgow, T. Evolution of the molecular machines for protein import into mitochondria. Science 2006, 313, 314-318
-
(2006)
Science
, vol.313
, pp. 314-318
-
-
Dolezal, P.1
Likic, V.2
Tachezy, J.3
Lithgow, T.4
-
174
-
-
33646354157
-
Translocation of mitochondrial inner-membrane proteins: Conformation matters
-
De Marcos-Lousa, C.; Sideris, D.P.; Tokatlidis, K. Translocation of mitochondrial inner-membrane proteins: Conformation matters. Trends Biochem. Sci. 2006, 31, 259-267
-
(2006)
Trends Biochem. Sci.
, vol.31
, pp. 259-267
-
-
De Marcos-Lousa, C.1
Sideris, D.P.2
Tokatlidis, K.3
-
175
-
-
34848823742
-
Mitochondrial protein-import machinery: Correlating structure with function
-
Baker, M.J.; Frazier, A.E.; Gulbis, J.M.; Ryan, M.T. Mitochondrial protein-import machinery: Correlating structure with function. Trends Cell. Biol. 2007, 17, 456-464
-
(2007)
Trends Cell. Biol
, vol.17
, pp. 456-464
-
-
Baker, M.J.1
Frazier, A.E.2
Gulbis, J.M.3
Ryan, M.T.4
-
176
-
-
84940882047
-
The Broad Impact of TOM40 on Neurodegenerative Diseases in Aging
-
Gottschalk, W.K.; Lutz, M.W.; He, Y.T.; Saunders, A.M.; Burns, D.K.; Roses, A.D.; Chiba-Falek, O. The Broad Impact of TOM40 on Neurodegenerative Diseases in Aging. J. Parkinsons Dis. Alzheimers Dis. 2014, 1, 12
-
(2014)
J. Parkinsons Dis. Alzheimers Dis
, vol.1
, pp. 12
-
-
Gottschalk, W.K.1
Lutz, M.W.2
He, Y.T.3
Saunders, A.M.4
Burns, D.K.5
Roses, A.D.6
Chiba-Falek, O.7
-
177
-
-
84876561267
-
TOM40 mediates mitochondrial dysfunction induced by alpha-synuclein accumulation in Parkinson’s disease
-
Bender, A.; Desplats, P.; Spencer, B.; Rockenstein, E.; Adame, A.; Elstner, M.; Laub, C.; Mueller, S.; Koob, A.O.; Mante, M.; et al. TOM40 mediates mitochondrial dysfunction induced by alpha-synuclein accumulation in Parkinson’s disease. PLoS ONE 2013, 8, e62277
-
(2013)
Plos ONE
, vol.8
-
-
Bender, A.1
Desplats, P.2
Spencer, B.3
Rockenstein, E.4
Adame, A.5
Elstner, M.6
Laub, C.7
Mueller, S.8
Koob, A.O.9
Mante, M.10
-
178
-
-
84922820920
-
Unconventional PINK1 localization to the outer membrane of depolarized mitochondria drives Parkin recruitment
-
Okatsu, K.; Kimura, M.; Oka, T.; Tanaka, K.; Matsuda, N. Unconventional PINK1 localization to the outer membrane of depolarized mitochondria drives Parkin recruitment. J. Cell Sci. 2015, 128, 964-978
-
(2015)
J. Cell Sci
, vol.128
, pp. 964-978
-
-
Okatsu, K.1
Kimura, M.2
Oka, T.3
Tanaka, K.4
Matsuda, N.5
-
179
-
-
84874640848
-
Tom70 is essential for PINK1 import into mitochondria
-
Kato, H.; Lu, Q.; Rapaport, D.; Kozjak-Pavlovic, V. Tom70 is essential for PINK1 import into mitochondria. PLoS ONE 2013, 8, e58435
-
(2013)
Plos ONE
, vol.8
-
-
Kato, H.1
Lu, Q.2
Rapaport, D.3
Kozjak-Pavlovic, V.4
-
180
-
-
84863584524
-
Pharmacological rescue of mitochondrial deficits in iPSC-derived neural cells from patients with familial Parkinson’s disease
-
141ra90
-
Cooper, O.; Seo, H.; Andrabi, S.; Guardia-Laguarta, C.; Graziotto, J.; Sundberg, M.; McLean, J.R.; Carrillo-Reid, L.; Xie, Z.; Osborn, T.; et al. Pharmacological rescue of mitochondrial deficits in iPSC-derived neural cells from patients with familial Parkinson’s disease. Sci. Transl. Med. 2012, 4, 141ra90
-
(2012)
Sci. Transl. Med
, vol.4
-
-
Cooper, O.1
Seo, H.2
Andrabi, S.3
Guardia-Laguarta, C.4
Graziotto, J.5
Sundberg, M.6
McLean, J.R.7
Carrillo-Reid, L.8
Xie, Z.9
Osborn, T.10
-
181
-
-
84875140407
-
Genetic correction of a LRRK2 mutation in human iPSCs links parkinsonian neurodegeneration to ERK-dependent changes in gene expression
-
Reinhardt, P.; Schmid, B.; Burbulla, L.F.; Schondorf, D.C.; Wagner, L.; Glatza, M.; Hoing, S.; Hargus, G.; Heck, S.A.; Dhingra, A.; et al. Genetic correction of a LRRK2 mutation in human iPSCs links parkinsonian neurodegeneration to ERK-dependent changes in gene expression. Cell. Stem Cell. 2013, 12, 354-367
-
(2013)
Cell. Stem Cell
, vol.12
, pp. 354-367
-
-
Reinhardt, P.1
Schmid, B.2
Burbulla, L.F.3
Schondorf, D.C.4
Wagner, L.5
Glatza, M.6
Hoing, S.7
Hargus, G.8
Heck, S.A.9
Dhingra, A.10
-
182
-
-
84978932709
-
Products of the Parkinson’s disease-related glyoxalase DJ-1, D-lactate and glycolate, support mitochondrial membrane potential and neuronal survival
-
Toyoda, Y.; Erkut, C.; Pan-Montojo, F.; Boland, S.; Stewart, M.P.; Muller, D.J.; Wurst, W.; Hyman, A.A.; Kurzchalia, T.V. Products of the Parkinson’s disease-related glyoxalase DJ-1, D-lactate and glycolate, support mitochondrial membrane potential and neuronal survival. Biol. Open 2014, 3, 777-784
-
(2014)
Biol. Open
, vol.3
, pp. 777-784
-
-
Toyoda, Y.1
Erkut, C.2
Pan-Montojo, F.3
Boland, S.4
Stewart, M.P.5
Muller, D.J.6
Wurst, W.7
Hyman, A.A.8
Kurzchalia, T.V.9
-
183
-
-
84939145610
-
LRRK2 Pharmacological Inhibition Abates alpha-Synuclein Induced Neurodegeneration
-
Daher, J.P.; Abdelmotilib, H.A.; Hu, X.; Volpicelli-Daley, L.A.; Moehle, M.S.; Fraser, K.B.; Needle, E.; Chen, Y.; Steyn, S.J.; Galatsis, P.; et al. LRRK2 Pharmacological Inhibition Abates alpha-Synuclein Induced Neurodegeneration. J. Biol. Chem. 2015, 290, 19433-19444
-
(2015)
J. Biol. Chem.
, vol.290
, pp. 19433-19444
-
-
Daher, J.P.1
Abdelmotilib, H.A.2
Hu, X.3
Volpicelli-Daley, L.A.4
Moehle, M.S.5
Fraser, K.B.6
Needle, E.7
Chen, Y.8
Steyn, S.J.9
Galatsis, P.10
-
184
-
-
84928796998
-
A novel GTP-binding inhibitor, FX2149, attenuates LRRK2 toxicity in Parkinson’s disease models
-
Li, T.; He, X.; Thomas, J.M.; Yang, D.; Zhong, S.; Xue, F.; Smith, W.W. A novel GTP-binding inhibitor, FX2149, attenuates LRRK2 toxicity in Parkinson’s disease models. PLoS ONE 2015, 10, e0122461
-
(2015)
Plos ONE
, vol.10
-
-
Li, T.1
He, X.2
Thomas, J.M.3
Yang, D.4
Zhong, S.5
Xue, F.6
Smith, W.W.7
-
185
-
-
84910684941
-
Neuroprotective effects of aldehyde dehydrogenase 2 activation in rotenone-induced cellular and animal models of parkinsonism. Exp
-
Chiu, C.C.; Yeh, T.H.; Lai, S.C.; Wu-Chou, Y.H.; Chen, C.H.; Mochly-Rosen, D.; Huang, Y.C.; Chen, Y.J.; Chen, C.L.; Chang, Y.M.; et al. Neuroprotective effects of aldehyde dehydrogenase 2 activation in rotenone-induced cellular and animal models of parkinsonism. Exp. Neurol. 2015, 263, 244-253
-
(2015)
Neurol
, vol.263
, pp. 244-253
-
-
Chiu, C.C.1
Yeh, T.H.2
Lai, S.C.3
Wu-Chou, Y.H.4
Chen, C.H.5
Mochly-Rosen, D.6
Huang, Y.C.7
Chen, Y.J.8
Chen, C.L.9
Chang, Y.M.10
-
186
-
-
84903638079
-
Chronic administration of cholesterol oximes in mice increases transcription of cytoprotective genes and improves transcriptome alterations induced by alpha-synuclein overexpression in nigrostriatal dopaminergic neurons
-
Richter, F.; Gao, F.; Medvedeva, V.; Lee, P.; Bove, N.; Fleming, S.M.; Michaud, M.; Lemesre, V.; Patassini, S.; de La Rosa, K.; et al. Chronic administration of cholesterol oximes in mice increases transcription of cytoprotective genes and improves transcriptome alterations induced by alpha-synuclein overexpression in nigrostriatal dopaminergic neurons. Neurobiol. Dis. 2014, 69, 263-275
-
(2014)
Neurobiol. Dis
, vol.69
, pp. 263-275
-
-
Richter, F.1
Gao, F.2
Medvedeva, V.3
Lee, P.4
Bove, N.5
Fleming, S.M.6
Michaud, M.7
Lemesre, V.8
Patassini, S.9
De La Rosa, K.10
-
187
-
-
84923355252
-
Drp1 inhibition attenuates neurotoxicity and dopamine release deficits in vivo
-
Rappold, P.M.; Cui, M.; Grima, J.C.; Fan, R.Z.; de Mesy-Bentley, K.L.; Chen, L.; Zhuang, X.; Bowers, W.J.; Tieu, K. Drp1 inhibition attenuates neurotoxicity and dopamine release deficits in vivo. Nat. Commun. 2014, 5, 5244
-
(2014)
Nat. Commun
, vol.5
-
-
Rappold, P.M.1
Cui, M.2
Grima, J.C.3
Fan, R.Z.4
De Mesy-Bentley, K.L.5
Chen, L.6
Zhuang, X.7
Bowers, W.J.8
Tieu, K.9
-
188
-
-
84936985419
-
The novel mitochondrial iron chelator 5-((methylamino)methyl)-8-hydroxyquinoline protects against mitochondrial-induced oxidative damage and neuronal death
-
Mena, N.P.; Garcia-Beltran, O.; Lourido, F.; Urrutia, P.J.; Mena, R.; Castro-Castillo, V.; Cassels, B.K.; Nunez, M.T. The novel mitochondrial iron chelator 5-((methylamino)methyl)-8-hydroxyquinoline protects against mitochondrial-induced oxidative damage and neuronal death. Biochem. Biophys. Res. Commun. 2015, 463, 787-792
-
(2015)
Biochem. Biophys. Res. Commun
, vol.463
, pp. 787-792
-
-
Mena, N.P.1
Garcia-Beltran, O.2
Lourido, F.3
Urrutia, P.J.4
Mena, R.5
Castro-Castillo, V.6
Cassels, B.K.7
Nunez, M.T.8
-
189
-
-
84875271208
-
Rapamycin protects the mitochondria against oxidative stress and apoptosis in a rat model of Parkinson’s disease
-
Jiang, J.; Zuo, Y.; Gu, Z. Rapamycin protects the mitochondria against oxidative stress and apoptosis in a rat model of Parkinson’s disease. Int. J. Mol. Med. 2013, 31, 825-832
-
(2013)
Int. J. Mol. Med.
, vol.31
, pp. 825-832
-
-
Jiang, J.1
Zuo, Y.2
Gu, Z.3
-
190
-
-
79958024002
-
Reesaul, H.; et al. Edaravone guards dopamine neurons in a rotenone model for Parkinson’s disease
-
Xiong, N.; Xiong, J.; Khare, G.; Chen, C.; Huang, J.; Zhao, Y.; Zhang, Z.; Qiao, X.; Feng, Y.; Reesaul, H.; et al. Edaravone guards dopamine neurons in a rotenone model for Parkinson’s disease. PLoS ONE 2011, 6, e20677
-
(2011)
Plos ONE
, vol.6
-
-
Xiong, N.1
Xiong, J.2
Khare, G.3
Chen, C.4
Huang, J.5
Zhao, Y.6
Zhang, Z.7
Qiao, X.8
Feng, Y.9
-
191
-
-
0035170284
-
Melatonin protects against 6-OHDA-induced neurotoxicity in rats
-
Dabbeni-Sala, F.; di Santo, S.; Franceschini, D.; Skaper, S.D.; Giusti, P. Melatonin protects against 6-OHDA-induced neurotoxicity in rats: A role for mitochondrial complex I activity. FASEB J. 2001, 15, 164-170
-
(2001)
A Role for Mitochondrial Complex I Activity. FASEB J.
, vol.15
, pp. 164-170
-
-
Dabbeni-Sala, F.1
Di Santo, S.2
Franceschini, D.3
Skaper, S.D.4
Giusti, P.5
-
192
-
-
84894169932
-
Antioxidant potential of melatonin enhances the response to L-dopa in 1-methyl 4-phenyl 1,2,3,6-tetrahydropyridine-parkinsonian mice
-
Zaitone, S.A.; Hammad, L.N.; Farag, N.E. Antioxidant potential of melatonin enhances the response to L-dopa in 1-methyl 4-phenyl 1,2,3,6-tetrahydropyridine-parkinsonian mice. Pharmacol. Rep. 2013, 65, 1213-1226
-
(2013)
Pharmacol. Rep
, vol.65
, pp. 1213-1226
-
-
Zaitone, S.A.1
Hammad, L.N.2
Farag, N.E.3
-
193
-
-
84874547093
-
Quercetin upregulates mitochondrial complex-I activity to protect against programmed cell death in rotenone model of Parkinson’s disease in rats
-
Karuppagounder, S.S.; Madathil, S.K.; Pandey, M.; Haobam, R.; Rajamma, U.; Mohanakumar, K.P. Quercetin upregulates mitochondrial complex-I activity to protect against programmed cell death in rotenone model of Parkinson’s disease in rats. Neuroscience 2013, 236, 136-148
-
(2013)
Neuroscience
, vol.236
, pp. 136-148
-
-
Karuppagounder, S.S.1
Madathil, S.K.2
Pandey, M.3
Haobam, R.4
Rajamma, U.5
Mohanakumar, K.P.6
-
194
-
-
84904568487
-
CNB-001, a novel pyrazole derivative mitigates motor impairments associated with neurodegeneration via suppression of neuroinflammatory and apoptotic response in experimental Parkinson’s disease mice
-
Jayaraj, R.L.; Elangovan, N.; Dhanalakshmi, C.; Manivasagam, T.; Essa, M.M. CNB-001, a novel pyrazole derivative mitigates motor impairments associated with neurodegeneration via suppression of neuroinflammatory and apoptotic response in experimental Parkinson’s disease mice. Chem. Biol. Interact. 2014, 220, 149-157
-
(2014)
Chem. Biol. Interact
, vol.220
, pp. 149-157
-
-
Jayaraj, R.L.1
Elangovan, N.2
Dhanalakshmi, C.3
Manivasagam, T.4
Essa, M.M.5
-
195
-
-
81055140360
-
Intervention of mitochondrial dysfunction-oxidative stress-dependent apoptosis as a possible neuroprotective mechanism of alpha-lipoic acid against rotenone-induced parkinsonism and L-dopa toxicity
-
Abdin, A.A.; Sarhan, N.I. Intervention of mitochondrial dysfunction-oxidative stress-dependent apoptosis as a possible neuroprotective mechanism of alpha-lipoic acid against rotenone-induced parkinsonism and L-dopa toxicity. Neurosci. Res. 2011, 71, 387-395
-
(2011)
Neurosci. Res
, vol.71
, pp. 387-395
-
-
Abdin, A.A.1
Sarhan, N.I.2
-
196
-
-
79961208135
-
Protective effect of lycopene on oxidative stress and cognitive decline in rotenone induced model of Parkinson’s disease
-
Kaur, H.; Chauhan, S.; Sandhir, R. Protective effect of lycopene on oxidative stress and cognitive decline in rotenone induced model of Parkinson’s disease. Neurochem. Res. 2011, 36, 1435-1443
-
(2011)
Neurochem. Res
, vol.36
, pp. 1435-1443
-
-
Kaur, H.1
Chauhan, S.2
Sandhir, R.3
-
197
-
-
51749104191
-
Activation of aldehyde dehydrogenase-2 reduces ischemic damage to the heart
-
Chen, C.H.; Budas, G.R.; Churchill, E.N.; Disatnik, M.H.; Hurley, T.D.; Mochly-Rosen, D. Activation of aldehyde dehydrogenase-2 reduces ischemic damage to the heart. Science 2008, 321, 1493-1145
-
(2008)
Science
, vol.321
, pp. 1145-1493
-
-
Chen, C.H.1
Budas, G.R.2
Churchill, E.N.3
Disatnik, M.H.4
Hurley, T.D.5
Mochly-Rosen, D.6
-
198
-
-
34547123812
-
Identification and characterization of cholest-4-en-3-one, oxime (TRO19622), a novel drug candidate for amyotrophic lateral sclerosis
-
Bordet, T.; Buisson, B.; Michaud, M.; Drouot, C.; Galea, P.; Delaage, P.; Akentieva, N.P.; Evers, A.S.; Covey, D.F.; Ostuni, M.A.; et al. Identification and characterization of cholest-4-en-3-one, oxime (TRO19622), a novel drug candidate for amyotrophic lateral sclerosis. J. Pharmacol. Exp. Ther. 2007, 322, 709-720
-
(2007)
J. Pharmacol. Exp. Ther.
, vol.322
, pp. 709-720
-
-
Bordet, T.1
Buisson, B.2
Michaud, M.3
Drouot, C.4
Galea, P.5
Delaage, P.6
Akentieva, N.P.7
Evers, A.S.8
Covey, D.F.9
Ostuni, M.A.10
-
199
-
-
84919627671
-
Protective role of olesoxime against wild-type alphasynuclein-induced toxicity in human neuronally differentiated SHSY-5Y cells
-
Gouarne, C.; Tracz, J.; Paoli, M.G.; Deluca, V.; Seimandi, M.; Tardif, G.; Xilouri, M.; Stefanis, L.; Bordet, T.; Pruss, R.M. Protective role of olesoxime against wild-type alphasynuclein-induced toxicity in human neuronally differentiated SHSY-5Y cells. Br. J. Pharmacol. 2015, 172, 235-245
-
(2015)
Br. J. Pharmacol
, vol.172
, pp. 235-245
-
-
Gouarne, C.1
Tracz, J.2
Paoli, M.G.3
Deluca, V.4
Seimandi, M.5
Tardif, G.6
Xilouri, M.7
Stefanis, L.8
Bordet, T.9
Pruss, R.M.10
-
200
-
-
84929378587
-
Gomez-Serranillos, M.P. Mitochondria-Targeted Protective Compounds in Parkinson’s and Alzheimer’s Diseases
-
Fernandez-Moriano, C.; Gonzalez-Burgos, E.; Gomez-Serranillos, M.P. Mitochondria-Targeted Protective Compounds in Parkinson’s and Alzheimer’s Diseases. Oxid. Med. Cell. Longev. 2015, 2015, 408927
-
(2015)
Oxid. Med. Cell. Longev
, vol.2015
-
-
Fernandez-Moriano, C.1
Gonzalez-Burgos, E.2
-
201
-
-
84925012167
-
Therapeutic strategies in Parkinson’s disease: What we have learned from animal models
-
Valadas, J.S.; Vos, M.; Verstreken, P. Therapeutic strategies in Parkinson’s disease: What we have learned from animal models. Ann. N. Y. Acad. Sci. 2015, 1338, 16-37
-
(2015)
Ann. N. Y. Acad. Sci
, vol.1338
, pp. 16-37
-
-
Valadas, J.S.1
Vos, M.2
Verstreken, P.3
-
202
-
-
84901241148
-
Perspectives of drug-based neuroprotection targeting mitochondria
-
Procaccio, V.; Bris, C.; de la Barca, J.M.C.; Oca, F.; Chevrollier, A.; Amati-Bonneau, P.; Bonneau, D.; Reynier, P. Perspectives of drug-based neuroprotection targeting mitochondria. Rev. Neurol. (Paris) 2014, 170, 390-400
-
(2014)
Rev. Neurol. (Paris)
, vol.170
, pp. 390-400
-
-
Procaccio, V.1
Bris, C.2
De La Barca, J.M.C.3
Oca, F.4
Chevrollier, A.5
Amati-Bonneau, P.6
Bonneau, D.7
Reynier, P.8
-
203
-
-
84925882442
-
Mitochondria: Prospective targets for neuroprotection in Parkinson’s disease
-
Yadav, A.; Agarwal, S.; Tiwari, S.K.; Chaturvedi, R.K. Mitochondria: Prospective targets for neuroprotection in Parkinson’s disease. Curr. Pharm. Des. 2014, 20, 5558-5573
-
(2014)
Curr. Pharm. Des
, vol.20
, pp. 5558-5573
-
-
Yadav, A.1
Agarwal, S.2
Tiwari, S.K.3
Chaturvedi, R.K.4
|