-
1
-
-
60549083568
-
Mitochondrial dysfunction in neurodegenerative diseases
-
Schapira, A.H. (2008) Mitochondrial dysfunction in neurodegenerative diseases. Neurochem. Res., 33, 2502-2509.
-
(2008)
Neurochem. Res.
, vol.33
, pp. 2502-2509
-
-
Schapira, A.H.1
-
2
-
-
75749156257
-
PINK1 is selectively stabilized on impaired mitochondria to activate Parkin
-
Narendra, D.P., Jin, S.M., Tanaka, A., Suen, D.F., Gautier, C.A., Shen, J., Cookson, M.R. and Youle, R.J. (2010) PINK1 is selectively stabilized on impaired mitochondria to activate Parkin. PLoS Biol., 8, e1000298.
-
(2010)
PLoS Biol
, vol.8
-
-
Narendra, D.P.1
Jin, S.M.2
Tanaka, A.3
Suen, D.F.4
Gautier, C.A.5
Shen, J.6
Cookson, M.R.7
Youle, R.J.8
-
3
-
-
84857031377
-
Parkin, PINK1 and mitochondrial integrity: emerging concepts of mitochondrial dysfunction in Parkinson's disease
-
Pilsl, A. and Winklhofer, K.F. (2012) Parkin, PINK1 and mitochondrial integrity: emerging concepts of mitochondrial dysfunction in Parkinson's disease. Acta Neuropathol., 123, 173-188.
-
(2012)
Acta Neuropathol
, vol.123
, pp. 173-188
-
-
Pilsl, A.1
Winklhofer, K.F.2
-
4
-
-
33846636481
-
Progressive parkinsonism in mice with respiratorychain-deficient dopamine neurons
-
Ekstrand, M.I., Terzioglu, M., Galter, D., Zhu, S., Hofstetter, C., Lindqvist, E., Thams, S., Bergstrand, A., Hansson, F.S., Trifunovic, A. et al. (2007) Progressive parkinsonism in mice with respiratorychain-deficient dopamine neurons. Proc. Natl Acad. Sci. USA, 104, 1325-1330.
-
(2007)
Proc. Natl Acad. Sci. USA
, vol.104
, pp. 1325-1330
-
-
Ekstrand, M.I.1
Terzioglu, M.2
Galter, D.3
Zhu, S.4
Hofstetter, C.5
Lindqvist, E.6
Thams, S.7
Bergstrand, A.8
Hansson, F.S.9
Trifunovic, A.10
-
5
-
-
80051972817
-
Super-resolution microscopy reveals that mammalian mitochondrial nucleoids have a uniform size and frequently contain a single copy of mtDNA
-
Kukat, C., Wurm, C.A., Spahr, H., Falkenberg, M., Larsson, N.G. and Jakobs, S. (2011) Super-resolution microscopy reveals that mammalian mitochondrial nucleoids have a uniform size and frequently contain a single copy of mtDNA. Proc. Natl Acad. Sci. USA, 108, 13534-13539.
-
(2011)
Proc. Natl Acad. Sci. USA
, vol.108
, pp. 13534-13539
-
-
Kukat, C.1
Wurm, C.A.2
Spahr, H.3
Falkenberg, M.4
Larsson, N.G.5
Jakobs, S.6
-
7
-
-
79961239061
-
Impaired mitochondrial transport and Parkin-independent degeneration of respiratory chain-deficient dopamine neurons in vivo
-
Sterky, F.H., Lee, S., Wibom, R., Olson, L. and Larsson, N.G. (2011) Impaired mitochondrial transport and Parkin-independent degeneration of respiratory chain-deficient dopamine neurons in vivo. Proc. Natl Acad. Sci. USA, 108, 12937-12942.
-
(2011)
Proc. Natl Acad. Sci. USA
, vol.108
, pp. 12937-12942
-
-
Sterky, F.H.1
Lee, S.2
Wibom, R.3
Olson, L.4
Larsson, N.G.5
-
8
-
-
34250204271
-
The machines that divide and fuse mitochondria
-
Hoppins, S., Lackner, L. and Nunnari, J. (2007) The machines that divide and fuse mitochondria. Annu. Rev. Biochem., 76, 751-780.
-
(2007)
Annu. Rev. Biochem.
, vol.76
, pp. 751-780
-
-
Hoppins, S.1
Lackner, L.2
Nunnari, J.3
-
9
-
-
33750445482
-
Mitochondrial fusion and fission in mammals
-
Chan, D.C. (2006) Mitochondrial fusion and fission in mammals. Annu. Rev. Cell Dev. Biol., 22, 79-99.
-
(2006)
Annu. Rev. Cell Dev. Biol.
, vol.22
, pp. 79-99
-
-
Chan, D.C.1
-
10
-
-
0037455575
-
Mitofusins Mfn1 and Mfn2 coordinately regulate mitochondrial fusion and are essential for embryonic development
-
Chen, H., Detmer, S.A., Ewald, A.J., Griffin, E.E., Fraser, S.E. and Chan, D.C. (2003) Mitofusins Mfn1 and Mfn2 coordinately regulate mitochondrial fusion and are essential for embryonic development. J. Cell Biol., 160, 189-200.
-
(2003)
J. Cell Biol.
, vol.160
, pp. 189-200
-
-
Chen, H.1
Detmer, S.A.2
Ewald, A.J.3
Griffin, E.E.4
Fraser, S.E.5
Chan, D.C.6
-
11
-
-
34547601410
-
Mitochondrial fusion protects against neurodegeneration in the cerebellum
-
Chen, H., McCaffery, J.M. and Chan, D.C. (2007) Mitochondrial fusion protects against neurodegeneration in the cerebellum. Cell, 130, 548-562.
-
(2007)
Cell
, vol.130
, pp. 548-562
-
-
Chen, H.1
McCaffery, J.M.2
Chan, D.C.3
-
12
-
-
77951737783
-
Mitochondrial fusion is required for mtDNA stability in skeletal muscle and tolerance of mtDNA mutations
-
Chen, H., Vermulst, M., Wang, Y.E., Chomyn, A., Prolla, T.A., McCaffery, J.M. and Chan, D.C. (2010) Mitochondrial fusion is required for mtDNA stability in skeletal muscle and tolerance of mtDNA mutations. Cell, 141, 280-289.
-
(2010)
Cell
, vol.141
, pp. 280-289
-
-
Chen, H.1
Vermulst, M.2
Wang, Y.E.3
Chomyn, A.4
Prolla, T.A.5
McCaffery, J.M.6
Chan, D.C.7
-
13
-
-
0036369531
-
OPA1 (Kjer type) dominant optic atrophy: a novel mitochondrial disease
-
Delettre, C., Lenaers, G., Pelloquin, L., Belenguer, P. and Hamel, C.P. (2002) OPA1 (Kjer type) dominant optic atrophy: a novel mitochondrial disease. Mol. Genet. Metab., 75, 97-107.
-
(2002)
Mol. Genet. Metab.
, vol.75
, pp. 97-107
-
-
Delettre, C.1
Lenaers, G.2
Pelloquin, L.3
Belenguer, P.4
Hamel, C.P.5
-
14
-
-
2442589922
-
Mutations in the mitochondrial GTPase mitofusin 2 cause Charcot-Marie-Tooth neuropathy type 2A
-
Zuchner, S., Mersiyanova, I.V., Muglia, M., Bissar-Tadmouri, N., Rochelle, J., Dadali, E.L., Zappia, M., Nelis, E., Patitucci, A., Senderek, J. et al. (2004) Mutations in the mitochondrial GTPase mitofusin 2 cause Charcot-Marie-Tooth neuropathy type 2A. Nat. Genet., 36, 449-451.
-
(2004)
Nat. Genet.
, vol.36
, pp. 449-451
-
-
Zuchner, S.1
Mersiyanova, I.V.2
Muglia, M.3
Bissar-Tadmouri, N.4
Rochelle, J.5
Dadali, E.L.6
Zappia, M.7
Nelis, E.8
Patitucci, A.9
Senderek, J.10
-
15
-
-
38549110110
-
Fission and selective fusion govern mitochondrial segregation and elimination by autophagy
-
Twig, G., Elorza, A., Molina, A.J., Mohamed, H., Wikstrom, J.D., Walzer, G., Stiles, L., Haigh, S.E., Katz, S., Las, G. et al. (2008) Fission and selective fusion govern mitochondrial segregation and elimination by autophagy. EMBO J., 27, 433-446.
-
(2008)
EMBO J
, vol.27
, pp. 433-446
-
-
Twig, G.1
Elorza, A.2
Molina, A.J.3
Mohamed, H.4
Wikstrom, J.D.5
Walzer, G.6
Stiles, L.7
Haigh, S.E.8
Katz, S.9
Las, G.10
-
17
-
-
79954577302
-
Targeting mitochondrial dysfunction: role for PINK1 and Parkin in mitochondrial quality control
-
Narendra, D.P. and Youle, R.J. (2011) Targeting mitochondrial dysfunction: role for PINK1 and Parkin in mitochondrial quality control. Antioxid. Redox Signal., 14, 1929-1938.
-
(2011)
Antioxid. Redox Signal.
, vol.14
, pp. 1929-1938
-
-
Narendra, D.P.1
Youle, R.J.2
-
18
-
-
78649413837
-
Mitochondrial fusion and fission in cell life and death
-
Westermann, B. (2010) Mitochondrial fusion and fission in cell life and death. Nat. Rev. Mol. Cell Biol., 11, 872-884.
-
(2010)
Nat. Rev. Mol. Cell Biol.
, vol.11
, pp. 872-884
-
-
Westermann, B.1
-
19
-
-
78650729600
-
Proteasome and p97 mediate mitophagy and degradation of mitofusins induced by Parkin
-
Tanaka, A., Cleland, M.M., Xu, S., Narendra, D.P., Suen, D.F., Karbowski, M. and Youle, R.J. (2010) Proteasome and p97 mediate mitophagy and degradation of mitofusins induced by Parkin. J. Cell Biol., 191, 1367-1380.
-
(2010)
J. Cell Biol.
, vol.191
, pp. 1367-1380
-
-
Tanaka, A.1
Cleland, M.M.2
Xu, S.3
Narendra, D.P.4
Suen, D.F.5
Karbowski, M.6
Youle, R.J.7
-
20
-
-
79960493052
-
Parkin promotes the ubiquitination and degradation of the mitochondrial fusion factor mitofusin 1
-
Glauser, L., Sonnay, S., Stafa, K. and Moore, D.J. (2011) Parkin promotes the ubiquitination and degradation of the mitochondrial fusion factor mitofusin 1. J. Neurochem., 118, 636-645.
-
(2011)
J. Neurochem.
, vol.118
, pp. 636-645
-
-
Glauser, L.1
Sonnay, S.2
Stafa, K.3
Moore, D.J.4
-
21
-
-
77950384477
-
Drosophila Parkin requires PINK1 for mitochondrial translocation and ubiquitinates mitofusin
-
Ziviani, E., Tao, R.N. and Whitworth, A.J. (2010) Drosophila Parkin requires PINK1 for mitochondrial translocation and ubiquitinates mitofusin. Proc. Natl Acad. Sci. USA, 107, 5018-5023.
-
(2010)
Proc. Natl Acad. Sci. USA
, vol.107
, pp. 5018-5023
-
-
Ziviani, E.1
Tao, R.N.2
Whitworth, A.J.3
-
22
-
-
55749090654
-
The Parkinson's disease genes pink1 and parkin promote mitochondrial fission and/or inhibit fusion in Drosophila
-
Deng, H., Dodson, M.W., Huang, H. and Guo, M. (2008) The Parkinson's disease genes pink1 and parkin promote mitochondrial fission and/or inhibit fusion in Drosophila. Proc. Natl Acad. Sci. USA, 105, 14503-14508.
-
(2008)
Proc. Natl Acad. Sci. USA
, vol.105
, pp. 14503-14508
-
-
Deng, H.1
Dodson, M.W.2
Huang, H.3
Guo, M.4
-
23
-
-
39449088321
-
The PINK1/Parkin pathway regulates mitochondrial morphology
-
Poole, A.C., Thomas, R.E., Andrews, L.A., McBride, H.M., Whitworth, A.J. and Pallanck, L.J. (2008) The PINK1/Parkin pathway regulates mitochondrial morphology. Proc. Natl Acad. Sci. USA, 105, 1638-1643.
-
(2008)
Proc. Natl Acad. Sci. USA
, vol.105
, pp. 1638-1643
-
-
Poole, A.C.1
Thomas, R.E.2
Andrews, L.A.3
McBride, H.M.4
Whitworth, A.J.5
Pallanck, L.J.6
-
24
-
-
0032924872
-
Dilated cardiomyopathy and atrioventricular conduction blocks induced by heart-specific inactivation of mitochondrial DNA gene expression
-
Wang, J., Wilhelmsson, H., Graff, C., Li, H., Oldfors, A., Rustin, P., Bruning, J.C., Kahn, C.R., Clayton, D.A., Barsh, G.S. et al. (1999) Dilated cardiomyopathy and atrioventricular conduction blocks induced by heart-specific inactivation of mitochondrial DNA gene expression. Nat. Genet., 21, 133-137.
-
(1999)
Nat. Genet.
, vol.21
, pp. 133-137
-
-
Wang, J.1
Wilhelmsson, H.2
Graff, C.3
Li, H.4
Oldfors, A.5
Rustin, P.6
Bruning, J.C.7
Kahn, C.R.8
Clayton, D.A.9
Barsh, G.S.10
-
25
-
-
58149314211
-
Parkin is recruited selectively to impaired mitochondria and promotes their autophagy
-
Narendra, D., Tanaka, A., Suen, D.F. and Youle, R.J. (2008) Parkin is recruited selectively to impaired mitochondria and promotes their autophagy. J. Cell Biol., 183, 795-803.
-
(2008)
J. Cell Biol.
, vol.183
, pp. 795-803
-
-
Narendra, D.1
Tanaka, A.2
Suen, D.F.3
Youle, R.J.4
-
26
-
-
77951181836
-
PINK1 stabilized by mitochondrial depolarization recruits Parkin to damaged mitochondria and activates latent Parkin for mitophagy
-
Matsuda, N., Sato, S., Shiba, K., Okatsu, K., Saisho, K., Gautier, C.A., Sou, Y.S., Saiki, S., Kawajiri, S., Sato, F. et al. (2010) PINK1 stabilized by mitochondrial depolarization recruits Parkin to damaged mitochondria and activates latent Parkin for mitophagy. J. Cell Biol., 189, 211-221.
-
(2010)
J. Cell Biol.
, vol.189
, pp. 211-221
-
-
Matsuda, N.1
Sato, S.2
Shiba, K.3
Okatsu, K.4
Saisho, K.5
Gautier, C.A.6
Sou, Y.S.7
Saiki, S.8
Kawajiri, S.9
Sato, F.10
-
27
-
-
0021334307
-
Apparent sprouting of striatal serotonergic terminals after dopamine-depleting brain lesions in neonatal rats
-
Stachowiak, M.K., Bruno, J.P., Snyder, A.M., Stricker, E.M. and Zigmond, M.J. (1984) Apparent sprouting of striatal serotonergic terminals after dopamine-depleting brain lesions in neonatal rats. Brain Res., 291, 164-167.
-
(1984)
Brain Res
, vol.291
, pp. 164-167
-
-
Stachowiak, M.K.1
Bruno, J.P.2
Snyder, A.M.3
Stricker, E.M.4
Zigmond, M.J.5
-
28
-
-
77952926102
-
Clinical progression in Parkinson disease and the neurobiology of axons
-
Cheng, H.C., Ulane, C.M. and Burke, R.E. (2010) Clinical progression in Parkinson disease and the neurobiology of axons. Ann. Neurol., 67, 715-725.
-
(2010)
Ann. Neurol.
, vol.67
, pp. 715-725
-
-
Cheng, H.C.1
Ulane, C.M.2
Burke, R.E.3
-
29
-
-
84868127674
-
Loss of Mfn2 results in progressive, retrograde degeneration of dopaminergic neurons in the nigrostriatal circuit
-
10.1093/hmg/dds311
-
Pham, A.H., Meng, S., Chu, Q.N. and Chan, D.C. (2012) Loss of Mfn2 results in progressive, retrograde degeneration of dopaminergic neurons in the nigrostriatal circuit. Hum. Mol. Genet., 10.1093/hmg/dds311.
-
(2012)
Hum. Mol. Genet
-
-
Pham, A.H.1
Meng, S.2
Chu, Q.N.3
Chan, D.C.4
-
30
-
-
84858397292
-
Mitofusin2 mutations disrupt axonal mitochondrial positioning and promote axon degeneration
-
Misko, A.L., Sasaki, Y., Tuck, E., Milbrandt, J. and Baloh, R.H. (2012) Mitofusin2 mutations disrupt axonal mitochondrial positioning and promote axon degeneration. J. Neurosci., 32, 4145-4155.
-
(2012)
J. Neurosci.
, vol.32
, pp. 4145-4155
-
-
Misko, A.L.1
Sasaki, Y.2
Tuck, E.3
Milbrandt, J.4
Baloh, R.H.5
-
31
-
-
0015863792
-
Prenatal development of the biogenic amine systems of the mouse brain
-
Golden, G.S. (1973) Prenatal development of the biogenic amine systems of the mouse brain. Dev. Biol., 33, 300-311.
-
(1973)
Dev. Biol.
, vol.33
, pp. 300-311
-
-
Golden, G.S.1
-
32
-
-
0015441424
-
Early prenatal ontogeny of central monoamine neurons in the rat: fluorescence histochemical observations
-
Olson, L. and Seiger, A. (1972) Early prenatal ontogeny of central monoamine neurons in the rat: fluorescence histochemical observations. Z. Anat. Entwicklungsgesch., 137, 301-316.
-
(1972)
Z. Anat. Entwicklungsgesch.
, vol.137
, pp. 301-316
-
-
Olson, L.1
Seiger, A.2
-
33
-
-
0023390552
-
The postnatal development of the dopamine-containing innervation of dorsal and ventral striatum: effects of the weaver gene
-
Roffler-Tarlov, S. and Graybiel, A.M. (1987) The postnatal development of the dopamine-containing innervation of dorsal and ventral striatum: effects of the weaver gene. J. Neurosci., 7, 2364-2372.
-
(1987)
J. Neurosci.
, vol.7
, pp. 2364-2372
-
-
Roffler-Tarlov, S.1
Graybiel, A.M.2
-
34
-
-
0015810881
-
Late prenatal ontogeny of central monoamine neurons in the rat: fluorescence histochemical observations
-
Seiger, A. and Olson, L. (1973) Late prenatal ontogeny of central monoamine neurons in the rat: fluorescence histochemical observations. Z. Anat. Entwicklungsgesch., 140, 281-318.
-
(1973)
Z. Anat. Entwicklungsgesch.
, vol.140
, pp. 281-318
-
-
Seiger, A.1
Olson, L.2
-
35
-
-
77949801029
-
Mitofusin 2 is necessary for transport of axonal mitochondria and interacts with the Miro/Milton complex
-
Misko, A., Jiang, S., Wegorzewska, I., Milbrandt, J. and Baloh, R.H. (2010) Mitofusin 2 is necessary for transport of axonal mitochondria and interacts with the Miro/Milton complex. J. Neurosci., 30, 4232-4240.
-
(2010)
J. Neurosci.
, vol.30
, pp. 4232-4240
-
-
Misko, A.1
Jiang, S.2
Wegorzewska, I.3
Milbrandt, J.4
Baloh, R.H.5
-
36
-
-
57349100367
-
Mitofusin 2 tethers endoplasmic reticulum to mitochondria
-
de Brito, O.M. and Scorrano, L. (2008) Mitofusin 2 tethers endoplasmic reticulum to mitochondria. Nature, 456, 605-610.
-
(2008)
Nature
, vol.456
, pp. 605-610
-
-
de Brito, O.M.1
Scorrano, L.2
-
37
-
-
84856976662
-
Altered dopamine metabolism and increased vulnerability to MPTP in mice with partial deficiency of mitochondrial complex I in dopamine neurons
-
Sterky, F.H., Hoffman, A.F., Milenkovic, D., Bao, B., Paganelli, A., Edgar, D., Wibom, R., Lupica, C.R., Olson, L. and Larsson, N.G. (2012) Altered dopamine metabolism and increased vulnerability to MPTP in mice with partial deficiency of mitochondrial complex I in dopamine neurons. Hum. Mol. Genet., 21, 1078-1089.
-
(2012)
Hum. Mol. Genet.
, vol.21
, pp. 1078-1089
-
-
Sterky, F.H.1
Hoffman, A.F.2
Milenkovic, D.3
Bao, B.4
Paganelli, A.5
Edgar, D.6
Wibom, R.7
Lupica, C.R.8
Olson, L.9
Larsson, N.G.10
-
38
-
-
0026705725
-
Sensitive mRNA detection using unfixed tissue: combined radioactive and non-radioactive in situ hybridization histochemistry
-
Dagerlind, A., Friberg, K., Bean, A.J. and Hokfelt, T. (1992) Sensitive mRNA detection using unfixed tissue: combined radioactive and non-radioactive in situ hybridization histochemistry. Histochemistry, 98, 39-49.
-
(1992)
Histochemistry
, vol.98
, pp. 39-49
-
-
Dagerlind, A.1
Friberg, K.2
Bean, A.J.3
Hokfelt, T.4
-
39
-
-
66049136339
-
A comparison of model-based (2D) and design-based (3D) stereological methods for estimating cell number in the substantia nigra pars compacta (SNpc) of the C57BL/6J mouse
-
Baquet, Z.C., Williams, D., Brody, J. and Smeyne, R.J. (2009) A comparison of model-based (2D) and design-based (3D) stereological methods for estimating cell number in the substantia nigra pars compacta (SNpc) of the C57BL/6J mouse. Neuroscience, 161, 1082-1090.
-
(2009)
Neuroscience
, vol.161
, pp. 1082-1090
-
-
Baquet, Z.C.1
Williams, D.2
Brody, J.3
Smeyne, R.J.4
|