-
1
-
-
0034643838
-
Prevalence of Parkinson's disease in Europe: A collaborative study of population-based cohorts
-
Neurologic Diseases in the Elderly Research Group
-
Rijk MC de, Launer LJ, Berger K, Breteler MM, Dartigues JF, Baldereschi M, Fratiglioni L, Lobo A, Martinez-Lage J, Trenkwalder C, Hofman A (2000) Prevalence of Parkinson's disease in Europe: a collaborative study of population-based cohorts. Neurologic Diseases in the Elderly Research Group. Neurology 54:S21-S23
-
(2000)
Neurology
, vol.54
-
-
De Rijk, M.C.1
Launer, L.J.2
Berger, K.3
Breteler, M.M.4
Dartigues, J.F.5
Baldereschi, M.6
Fratiglioni, L.7
Lobo, A.8
Martinez-Lage, J.9
Trenkwalder, C.10
Hofman, A.11
-
2
-
-
0032497504
-
Parkinson's disease. First of two parts
-
Lang AE, Lozano AM (1998) Parkinson's disease. First of two parts. N Engl J Med 339:1044-1053
-
(1998)
N Engl J Med
, vol.339
, pp. 1044-1053
-
-
Lang, A.E.1
Lozano, A.M.2
-
3
-
-
0037154184
-
Recent advances in the genetics and pathogenesis of Parkinson disease
-
Mouradian MM (2002) Recent advances in the genetics and pathogenesis of Parkinson disease. Neurology 58:179-185
-
(2002)
Neurology
, vol.58
, pp. 179-185
-
-
Mouradian, M.M.1
-
4
-
-
0037240325
-
Rare genetic mutations shed light on the pathogenesis of Parkinson disease
-
Dawson TM, Dawson VL (2003) Rare genetic mutations shed light on the pathogenesis of Parkinson disease. J Clin Invest 111:145-151
-
(2003)
J Clin Invest
, vol.111
, pp. 145-151
-
-
Dawson, T.M.1
Dawson, V.L.2
-
5
-
-
0036830525
-
A susceptibility gene for late-onset idiopathic Parkinson's disease
-
Hicks AA, Petursson H, Jonsson T, Stefansson H, Johannsdottir HS, Sainz J, Frigge ML, Kong A, Gulcher JR, Stefansson K, Sveinbjornsdottir S (2002) A susceptibility gene for late-onset idiopathic Parkinson's disease. Ann Neurol 52:549-555
-
(2002)
Ann Neurol
, vol.52
, pp. 549-555
-
-
Hicks, A.A.1
Petursson, H.2
Jonsson, T.3
Stefansson, H.4
Johannsdottir, H.S.5
Sainz, J.6
Frigge, M.L.7
Kong, A.8
Gulcher, J.R.9
Stefansson, K.10
Sveinbjornsdottir, S.11
-
6
-
-
0345701479
-
Significant linkage of Parkinson disease to chromosome 2q36-37
-
Pankratz N, Nichols WC, Uniacke SK, Halter C, Rudolph A, Shults C, Conneally PM, Foroud T (2003) Significant linkage of Parkinson disease to chromosome 2q36-37. Am J Hum Genet 72:1053-1057
-
(2003)
Am J Hum Genet
, vol.72
, pp. 1053-1057
-
-
Pankratz, N.1
Nichols, W.C.2
Uniacke, S.K.3
Halter, C.4
Rudolph, A.5
Shults, C.6
Conneally, P.M.7
Foroud, T.8
-
7
-
-
0032102455
-
The synucleins: A family of proteins involved in synaptic function, plasticity, neurodegeneration and disease
-
Clayton DF, George JM (1998) The synucleins: a family of proteins involved in synaptic function, plasticity, neurodegeneration and disease. Trends Neurosci 21:249-254
-
(1998)
Trends Neurosci
, vol.21
, pp. 249-254
-
-
Clayton, D.F.1
George, J.M.2
-
8
-
-
0034193399
-
Synucleins are developmentally expressed, and alpha-synuclein regulates the size of the presynaptic vesicular pool in primary hippocampal neurons
-
Murphy DD, Rueter SM, Trojanowski JQ, Lee VM (2000) Synucleins are developmentally expressed, and alpha-synuclein regulates the size of the presynaptic vesicular pool in primary hippocampal neurons. J Neurosci 20:3214-3220
-
(2000)
J Neurosci
, vol.20
, pp. 3214-3220
-
-
Murphy, D.D.1
Rueter, S.M.2
Trojanowski, J.Q.3
Lee, V.M.4
-
9
-
-
0037109727
-
Synaptic vesicle depletion correlates with attenuated synaptic responses to prolonged repetitive stimulation in mice lacking alpha-synuclein
-
Cabin DE, Shimazu K, Murphy D, Cole NB, Gottschalk W, McIlwain KL, Orrison B, Chen A, Ellis CE, Paylor R, Lu B, Nussbaum RL (2002) Synaptic vesicle depletion correlates with attenuated synaptic responses to prolonged repetitive stimulation in mice lacking alpha-synuclein. J Neurosci 22:8797-8807
-
(2002)
J Neurosci
, vol.22
, pp. 8797-8807
-
-
Cabin, D.E.1
Shimazu, K.2
Murphy, D.3
Cole, N.B.4
Gottschalk, W.5
McIlwain, K.L.6
Orrison, B.7
Chen, A.8
Ellis, C.E.9
Paylor, R.10
Lu, B.11
Nussbaum, R.L.12
-
10
-
-
0030744876
-
Mutation in the alpha-synuclein gene identified in families with Parkinson's disease
-
Polymeropoulos MH, Lavedan C, Leroy E, Ide SE, Dehejia A, Dutra A, Pike B, Root H, Rubenstein J, Boyer R, Stenroos ES, Chandrasekharappa S, Athanassiadou A, Papapetropoulos T, Johnson WG, Lazzarini AM, Duvoisin RC, Di Iorio G, Golbe LI, Nussbaum RL (1997) Mutation in the alpha-synuclein gene identified in families with Parkinson's disease. Science 276:2045-2047
-
(1997)
Science
, vol.276
, pp. 2045-2047
-
-
Polymeropoulos, M.H.1
Lavedan, C.2
Leroy, E.3
Ide, S.E.4
Dehejia, A.5
Dutra, A.6
Pike, B.7
Root, H.8
Rubenstein, J.9
Boyer, R.10
Stenroos, E.S.11
Chandrasekharappa, S.12
Athanassiadou, A.13
Papapetropoulos, T.14
Johnson, W.G.15
Lazzarini, A.M.16
Duvoisin, R.C.17
Di Iorio, G.18
Golbe, L.I.19
Nussbaum, R.L.20
more..
-
11
-
-
0031990490
-
Ala30Pro mutation in the gene encoding alpha-synuclein in Parkinson's disease
-
Kruger R, Kühn W, Muller T, Woitalla D, Graeber M, Kosel S, Przuntek H, Epplen JT, Schols L, Riess O (1998) Ala30Pro mutation in the gene encoding alpha-synuclein in Parkinson's disease. Nat Genet 18:106-108
-
(1998)
Nat Genet
, vol.18
, pp. 106-108
-
-
Kruger, R.1
Kühn, W.2
Muller, T.3
Woitalla, D.4
Graeber, M.5
Kosel, S.6
Przuntek, H.7
Epplen, J.T.8
Schols, L.9
Riess, O.10
-
12
-
-
0035409575
-
Alpha-synuclein and neurodegenerative diseases
-
Goedert M (2001) Alpha-synuclein and neurodegenerative diseases. Nat Rev Neurosci 2:492-501
-
(2001)
Nat Rev Neurosci
, vol.2
, pp. 492-501
-
-
Goedert, M.1
-
13
-
-
0036720019
-
Mouse and fly models of neurodegeneration
-
Zoghbi HY, Botas J (2002) Mouse and fly models of neurodegeneration. Trends Genet 18:463-471
-
(2002)
Trends Genet
, vol.18
, pp. 463-471
-
-
Zoghbi, H.Y.1
Botas, J.2
-
14
-
-
0034646391
-
Fibrils formed in vitro from alpha-synuclein and two mutant forms linked to Parkinson's disease are typical amyloid
-
Conway KA, Harper JD, Lansbury PT Jr (2000) Fibrils formed in vitro from alpha-synuclein and two mutant forms linked to Parkinson's disease are typical amyloid. Biochemistry 39:2552-2563
-
(2000)
Biochemistry
, vol.39
, pp. 2552-2563
-
-
Conway, K.A.1
Harper, J.D.2
Lansbury Jr., P.T.3
-
15
-
-
0037041420
-
Inherent toxicity of aggregates implies a common mechanism for protein misfolding diseases
-
Bucciantini M, Giannoni E, Chiti F, Baroni F, Formigli L, Zurdo J, Taddei N, Ramponi G, Dobson CM, Stefani M (2002) Inherent toxicity of aggregates implies a common mechanism for protein misfolding diseases. Nature 416:507-511
-
(2002)
Nature
, vol.416
, pp. 507-511
-
-
Bucciantini, M.1
Giannoni, E.2
Chiti, F.3
Baroni, F.4
Formigli, L.5
Zurdo, J.6
Taddei, N.7
Ramponi, G.8
Dobson, C.M.9
Stefani, M.10
-
16
-
-
0035180285
-
Deposition of transthyretin in early stages of familial amyloidotic polyneuropathy: Evidence for toxicity of nonfibrillar aggregates
-
Sousa MM, Cardoso I, Fernandes R, Guimaraes A, Saraiva MJ (2001) Deposition of transthyretin in early stages of familial amyloidotic polyneuropathy: evidence for toxicity of nonfibrillar aggregates. Am J Pathol 159:1993-2000
-
(2001)
Am J Pathol
, vol.159
, pp. 1993-2000
-
-
Sousa, M.M.1
Cardoso, I.2
Fernandes, R.3
Guimaraes, A.4
Saraiva, M.J.5
-
17
-
-
0037154229
-
Requirement of an intact microtubule cytoskeleton for aggregation and inclusion body formation by a mutant huntingtin fragment
-
Muchowski PJ, Ning K, D'Souza-Schorey C, Fields S (2002) Requirement of an intact microtubule cytoskeleton for aggregation and inclusion body formation by a mutant huntingtin fragment. Proc Natl Acad Sci U S A 99:727-732
-
(2002)
Proc Natl Acad Sci U S A
, vol.99
, pp. 727-732
-
-
Muchowski, P.J.1
Ning, K.2
D'Souza-Schorey, C.3
Fields, S.4
-
18
-
-
0037041426
-
Naturally secreted oligomers of amyloid beta protein potently inhibit hippocampal long-term potentiation in vivo
-
Walsh DM, Klyubin I, Fadeeva JV, Cullen WK, Anwyl R, Wolfe MS, Rowan MJ, Selkoe DJ (2002) Naturally secreted oligomers of amyloid beta protein potently inhibit hippocampal long-term potentiation in vivo. Nature 416:535-539
-
(2002)
Nature
, vol.416
, pp. 535-539
-
-
Walsh, D.M.1
Klyubin, I.2
Fadeeva, J.V.3
Cullen, W.K.4
Anwyl, R.5
Wolfe, M.S.6
Rowan, M.J.7
Selkoe, D.J.8
-
19
-
-
0035947372
-
Impairment of the ubiquitin-proteasome system by protein aggregation
-
Bence NF, Sampat RM, Kopito RR (2001) Impairment of the ubiquitin-proteasome system by protein aggregation. Science 292:1552-1555
-
(2001)
Science
, vol.292
, pp. 1552-1555
-
-
Bence, N.F.1
Sampat, R.M.2
Kopito, R.R.3
-
20
-
-
0035870881
-
Inducible expression of mutant alpha-synuclein decreases proteasome activity and increases sensitivity to mitochondria-dependent apoptosis
-
Tanaka Y, Engelender S, Igarashi S, Rao RK, Wanner T, Tanzi RE, Sawa A, Dawson VL, Dawson TM, Ross CA (2001) Inducible expression of mutant alpha-synuclein decreases proteasome activity and increases sensitivity to mitochondria-dependent apoptosis. Hum Mol Genet 10:919-926
-
(2001)
Hum Mol Genet
, vol.10
, pp. 919-926
-
-
Tanaka, Y.1
Engelender, S.2
Igarashi, S.3
Rao, R.K.4
Wanner, T.5
Tanzi, R.E.6
Sawa, A.7
Dawson, V.L.8
Dawson, T.M.9
Ross, C.A.10
-
21
-
-
0033890821
-
Alpha-synuclein promotes mitochondrial deficit and oxidative stress
-
Hsu LJ, Sagara Y, Arroyo A, Rockenstein E, Sisk A, Mallory M, Wong J, Takenouchi T, Hashimoto M, Masliah E (2000) Alpha-synuclein promotes mitochondrial deficit and oxidative stress. Am J Pathol 157:401-410
-
(2000)
Am J Pathol
, vol.157
, pp. 401-410
-
-
Hsu, L.J.1
Sagara, Y.2
Arroyo, A.3
Rockenstein, E.4
Sisk, A.5
Mallory, M.6
Wong, J.7
Takenouchi, T.8
Hashimoto, M.9
Masliah, E.10
-
22
-
-
0037073748
-
Golgi fragmentation occurs in the cells with prefibrillar alpha-synuclein aggregates and precedes the formation of fibrillar inclusion
-
Gosavi N, Lee HJ, Lee JS, Patel S, Lee SJ (2002) Golgi fragmentation occurs in the cells with prefibrillar alpha-synuclein aggregates and precedes the formation of fibrillar inclusion. J Biol Chem 277:48984-48992
-
(2002)
J Biol Chem
, vol.277
, pp. 48984-48992
-
-
Gosavi, N.1
Lee, H.J.2
Lee, J.S.3
Patel, S.4
Lee, S.J.5
-
23
-
-
0035800097
-
Vesicle permeabilization by protofibrillar alpha-synuclein: Implications for the pathogenesis and treatment of Parkinson's disease
-
Volles MJ, Lee SJ, Rochet JC, Shtilerman MD, Ding TT, Kessler JC, Lansbury PT Jr (2001) Vesicle permeabilization by protofibrillar alpha-synuclein: implications for the pathogenesis and treatment of Parkinson's disease. Biochemistry 40:7812-7819
-
(2001)
Biochemistry
, vol.40
, pp. 7812-7819
-
-
Volles, M.J.1
Lee, S.J.2
Rochet, J.C.3
Shtilerman, M.D.4
Ding, T.T.5
Kessler, J.C.6
Lansbury Jr., P.T.7
-
24
-
-
0037064078
-
Effect of mutant alpha-synuclein on dopamine homeostasis in a new human mesencephalic cell line
-
Lotharius J, Barg S, Wiekop P, Lundberg C, Raymon HK, Brundin P (2002) Effect of mutant alpha-synuclein on dopamine homeostasis in a new human mesencephalic cell line. J Biol Chem 277:38884-38894
-
(2002)
J Biol Chem
, vol.277
, pp. 38884-38894
-
-
Lotharius, J.1
Barg, S.2
Wiekop, P.3
Lundberg, C.4
Raymon, H.K.5
Brundin, P.6
-
25
-
-
0032499264
-
Mutations in the parkin gene cause autosomal recessive juvenile parkinsonism
-
Kitada T, Asakawa S, Hattori N, Matsumine H, Yamamura Y, Minoshima S, Yokochi M, Mizuno Y, Shimizu N (1998) Mutations in the parkin gene cause autosomal recessive juvenile parkinsonism. Nature 392:605-608
-
(1998)
Nature
, vol.392
, pp. 605-608
-
-
Kitada, T.1
Asakawa, S.2
Hattori, N.3
Matsumine, H.4
Yamamura, Y.5
Minoshima, S.6
Yokochi, M.7
Mizuno, Y.8
Shimizu, N.9
-
26
-
-
0342368772
-
Association between early-onset Parkinson's disease and mutations in the parkin gene
-
French Parkinson's Disease Genetics Study Group
-
Lucking CB, Durr A, Bonifati V, Vaughan J, De Michele G, Gasser T, Harhangi BS, Meco G, Denefle P, Wood NW, Agid Y, Brice A (2000) Association between early-onset Parkinson's disease and mutations in the parkin gene. French Parkinson's Disease Genetics Study Group. N Engl J Med 342:1560-1567
-
(2000)
N Engl J Med
, vol.342
, pp. 1560-1567
-
-
Lucking, C.B.1
Durr, A.2
Bonifati, V.3
Vaughan, J.4
De Michele, G.5
Gasser, T.6
Harhangi, B.S.7
Meco, G.8
Denefle, P.9
Wood, N.W.10
Agid, Y.11
Brice, A.12
-
27
-
-
0033933048
-
Familial Parkinson disease gene product, parkin, is a ubiquitin-protein ligase
-
Shimura H, Hattori N, Kubo S, Mizuno Y, Asakawa S, Minoshima S, Shimizu N, Iwai K, Chiba T, Tanaka K, Suzuki T (2000) Familial Parkinson disease gene product, parkin, is a ubiquitin-protein ligase. Nat Genet 25:302-305
-
(2000)
Nat Genet
, vol.25
, pp. 302-305
-
-
Shimura, H.1
Hattori, N.2
Kubo, S.3
Mizuno, Y.4
Asakawa, S.5
Minoshima, S.6
Shimizu, N.7
Iwai, K.8
Chiba, T.9
Tanaka, K.10
Suzuki, T.11
-
28
-
-
0036083396
-
The ubiquitin-proteasome proteolytic pathway: Destruction for the sake of construction
-
Glickman MH, Ciechanover A (2002) The ubiquitin-proteasome proteolytic pathway: destruction for the sake of construction. Physiol Rev 82:373-428
-
(2002)
Physiol Rev
, vol.82
, pp. 373-428
-
-
Glickman, M.H.1
Ciechanover, A.2
-
29
-
-
0032190090
-
The ubiquitin pathway in Parkinson's disease
-
Leroy E, Boyer R, Auburger G, Leube B, Ulm G, Mezey E, Harta G, Brownstein MJ, Jonnalagada S, Chernova T, Dehejia A, Lavedan C, Gasser T, Steinbach PJ, Wilkinson KD, Polymeropoulos MH (1998) The ubiquitin pathway in Parkinson's disease. Nature 395:451-452
-
(1998)
Nature
, vol.395
, pp. 451-452
-
-
Leroy, E.1
Boyer, R.2
Auburger, G.3
Leube, B.4
Ulm, G.5
Mezey, E.6
Harta, G.7
Brownstein, M.J.8
Jonnalagada, S.9
Chernova, T.10
Dehejia, A.11
Lavedan, C.12
Gasser, T.13
Steinbach, P.J.14
Wilkinson, K.D.15
Polymeropoulos, M.H.16
-
30
-
-
10744224825
-
Ubiquitin carboxy-terminal·hydrolase L1 binds to and stabilizes monoubiquitin in neuron
-
Osaka H, Wang YL, Takada K, Takizawa S, Setsuie R, Li H, Sato Y, Nishikawa K, Sun YJ, Sakurai M, Harada T, Hara Y, Kimura I, Chiba S, Namikawa K, Kiyama H, Noda M, Aoki S, Wada K (2003) Ubiquitin carboxy- terminal·hydrolase L1 binds to and stabilizes monoubiquitin in neuron. Hum Mol Genet 12:1945-1958
-
(2003)
Hum Mol Genet
, vol.12
, pp. 1945-1958
-
-
Osaka, H.1
Wang, Y.L.2
Takada, K.3
Takizawa, S.4
Setsuie, R.5
Li, H.6
Sato, Y.7
Nishikawa, K.8
Sun, Y.J.9
Sakurai, M.10
Harada, T.11
Hara, Y.12
Kimura, I.13
Chiba, S.14
Namikawa, K.15
Kiyama, H.16
Noda, M.17
Aoki, S.18
Wada, K.19
-
31
-
-
0035854437
-
Ubiquitination of a new form of alpha-synuclein by parkin from human brain: Implications for Parkinson's disease
-
Shimura H, Schlossmacher MG, Hattori N, Frosch MP, Trockenbacher A, Schneider R, Mizuno Y, Kosik KS, Selkoe DJ (2001) Ubiquitination of a new form of alpha-synuclein by parkin from human brain: implications for Parkinson's disease. Science 293:263-269
-
(2001)
Science
, vol.293
, pp. 263-269
-
-
Shimura, H.1
Schlossmacher, M.G.2
Hattori, N.3
Frosch, M.P.4
Trockenbacher, A.5
Schneider, R.6
Mizuno, Y.7
Kosik, K.S.8
Selkoe, D.J.9
-
32
-
-
0032952414
-
Synphilin-1 associates with alpha-synuclein and promotes the formation of cytosolic inclusions
-
Engelender S, Kaminsky Z, Guo X, Sharp AH, Amaravi RK, Kleiderlein JJ, Margolis RL, Troncoso JC, Lanahan AA, Worley PF, Dawson VL, Dawson TM, Ross CA (1999) Synphilin-1 associates with alpha-synuclein and promotes the formation of cytosolic inclusions. Nat Genet 22:110-114
-
(1999)
Nat Genet
, vol.22
, pp. 110-114
-
-
Engelender, S.1
Kaminsky, Z.2
Guo, X.3
Sharp, A.H.4
Amaravi, R.K.5
Kleiderlein, J.J.6
Margolis, R.L.7
Troncoso, J.C.8
Lanahan, A.A.9
Worley, P.F.10
Dawson, V.L.11
Dawson, T.M.12
Ross, C.A.13
-
33
-
-
0034776095
-
Parkin ubiquitinates the alpha-synuclein-interacting protein, synphilin-1: Implications for Lewy-body formation in Parkinson disease
-
Chung KK, Zhang Y, Lim KL, Tanaka Y, Huang H, Gao J, Ross CA, Dawson VL, Dawson TM (2001) Parkin ubiquitinates the alpha-synuclein-interacting protein, synphilin-1: implications for Lewy-body formation in Parkinson disease. Nat Med 7:1144-1150
-
(2001)
Nat Med
, vol.7
, pp. 1144-1150
-
-
Chung, K.K.1
Zhang, Y.2
Lim, K.L.3
Tanaka, Y.4
Huang, H.5
Gao, J.6
Ross, C.A.7
Dawson, V.L.8
Dawson, T.M.9
-
34
-
-
0037468831
-
Parkin suppresses dopaminergic neuron-selective neurotoxicity induced by Pael-R in Drosophila
-
Yang Y, Nishimura I, Imai Y, Takahashi R, Lu B (2003) Parkin suppresses dopaminergic neuron-selective neurotoxicity induced by Pael-R in Drosophila. Neuron 37:911-924
-
(2003)
Neuron
, vol.37
, pp. 911-924
-
-
Yang, Y.1
Nishimura, I.2
Imai, Y.3
Takahashi, R.4
Lu, B.5
-
35
-
-
0037137702
-
Parkin protects against the toxicity associated with mutant alpha-synuclein: Proteasome dysfunction selectively affects catecholaminergic neurons
-
Petrucelli L, O'Farrell C, Lockhart PJ, Baptista M, Kehoe K, Vink L, Choi P, Wolozin B, Farrer M, Hardy J, Cookson MR (2002) Parkin protects against the toxicity associated with mutant alpha-synuclein: proteasome dysfunction selectively affects catecholaminergic neurons. Neuron 36:1007-1019
-
(2002)
Neuron
, vol.36
, pp. 1007-1019
-
-
Petrucelli, L.1
O'Farrell, C.2
Lockhart, P.J.3
Baptista, M.4
Kehoe, K.5
Vink, L.6
Choi, P.7
Wolozin, B.8
Farrer, M.9
Hardy, J.10
Cookson, M.R.11
-
36
-
-
0035068574
-
Localization of a novel locus for autosomal recessive early-onset parkinsonism, PARK6, on human chromosome 1p35-p36
-
Valente EM, Bentivoglio AR, Dixon PH, Ferraris A, Ialongo T, Frontali M, Albanese A, Wood NW (2001) Localization of a novel locus for autosomal recessive early-onset parkinsonism, PARK6, on human chromosome 1p35-p36. Am J Hum Genet 68:895-900
-
(2001)
Am J Hum Genet
, vol.68
, pp. 895-900
-
-
Valente, E.M.1
Bentivoglio, A.R.2
Dixon, P.H.3
Ferraris, A.4
Ialongo, T.5
Frontali, M.6
Albanese, A.7
Wood, N.W.8
-
37
-
-
0034892917
-
Park7, a novel locus for autosomal recessive early-onset parkinsonism, on chromosome 1p36
-
Duijn CM van, Dekker MC, Bonifati V, Galjaard RJ, Houwing-Duistermaat JJ, Snijders PJ, Testers L, Breedveld GJ, Horstink M, Sandkuijl LA, van Swieten JC, Oostra BA, Heutink P (2001) Park7, a novel locus for autosomal recessive early-onset parkinsonism, on chromosome 1p36. Am J Hum Genet 69:629-634
-
(2001)
Am J Hum Genet
, vol.69
, pp. 629-634
-
-
Van Duijn, C.M.1
Dekker, M.C.2
Bonifati, V.3
Galjaard, R.J.4
Houwing-Duistermaat, J.J.5
Snijders, P.J.6
Testers, L.7
Breedveld, G.J.8
Horstink, M.9
Sandkuijl, L.A.10
Van Swieten, J.C.11
Oostra, B.A.12
Heutink, P.13
-
38
-
-
0034796326
-
Kufor-Rakeb syndrome, pallido-pyramidal degeneration with supranuclear upgaze paresis and dementia, maps to 1p36
-
Hampshire DJ, Roberts E, Crow Y, Bond J, Mubaidin A, Wriekat AL, Al-Din A, Woods CG (2001) Kufor-Rakeb syndrome, pallido-pyramidal degeneration with supranuclear upgaze paresis and dementia, maps to 1p36. J Med Genet 38:680-682
-
(2001)
J Med Genet
, vol.38
, pp. 680-682
-
-
Hampshire, D.J.1
Roberts, E.2
Crow, Y.3
Bond, J.4
Mubaidin, A.5
Wriekat, A.L.6
Al-Din, A.7
Woods, C.G.8
-
39
-
-
18344393780
-
Age at onset in two common neurodegenerative diseases is genetically controlled
-
Li YJ, Scott WK, Hedges DJ, Zhang F, Gaskell PC, Nance MA, Watts RL, Hubble JP, Koller WC, Pahwa R, Stern MB, Hiner BC, Jankovic J, Allen FA Jr, Goetz CG, Mastaglia F, Stajich JM, Gibson RA, Middleton LT, Saunders AM, Scott BL, Small GW, Nicodemus KK, Reed AD, Schmechel DE, Welsh-Bohmer KA, Conneally PM, Roses AD, Gilbert JR, Vance JM, Haines JL, Pericak-Vance MA (2002) Age at onset in two common neurodegenerative diseases is genetically controlled. Am J Hum Genet 70:985-993
-
(2002)
Am J Hum Genet
, vol.70
, pp. 985-993
-
-
Li, Y.J.1
Scott, W.K.2
Hedges, D.J.3
Zhang, F.4
Gaskell, P.C.5
Nance, M.A.6
Watts, R.L.7
Hubble, J.P.8
Koller, W.C.9
Pahwa, R.10
Stern, M.B.11
Hiner, B.C.12
Jankovic, J.13
Allen Jr., F.A.14
Goetz, C.G.15
Mastaglia, F.16
Stajich, J.M.17
Gibson, R.A.18
Middleton, L.T.19
Saunders, A.M.20
Scott, B.L.21
Small, G.W.22
Nicodemus, K.K.23
Reed, A.D.24
Schmechel, D.E.25
Welsh-Bohmer, K.A.26
Conneally, P.M.27
Roses, A.D.28
Gilbert, J.R.29
Vance, J.M.30
Haines, J.L.31
Pericak-Vance, M.A.32
more..
-
40
-
-
0036151884
-
Localization of autosomal recessive early-onset parkinsonism to chromosome 1p36 (PARK7) in an independent dataset
-
Bonifati V, Breedveld GJ, Squitieri F, Vanacore N, Brustenghi P, Harhangi BS, Montagna P, Cannella M, Fabbrini G, Rizzu P, van Duijn CM, Oostra BA, Meco G, Heutink P (2002) Localization of autosomal recessive early-onset parkinsonism to chromosome 1p36 (PARK7) in an independent dataset. Ann Neurol 51:253-256
-
(2002)
Ann Neurol
, vol.51
, pp. 253-256
-
-
Bonifati, V.1
Breedveld, G.J.2
Squitieri, F.3
Vanacore, N.4
Brustenghi, P.5
Harhangi, B.S.6
Montagna, P.7
Cannella, M.8
Fabbrini, G.9
Rizzu, P.10
Van Duijn, C.M.11
Oostra, B.A.12
Meco, G.13
Heutink, P.14
-
41
-
-
0037428241
-
Mutations in the DJ-1 gene associated with autosomal recessive early-onset parkinsonism
-
Bonifati V, Rizzu P, van Baren MJ, Schaap O, Breedveld GJ, Krieger E, Dekker MC, Squitieri F, Ibanez P, Joosse M, van Dongen JW, Vanacore N, van Swieten JC, Brice A, Meco G, van Duijn CM, Oostra BA, Heutink P (2003) Mutations in the DJ-1 gene associated with autosomal recessive early-onset parkinsonism. Science 299:256-259
-
(2003)
Science
, vol.299
, pp. 256-259
-
-
Bonifati, V.1
Rizzu, P.2
Van Baren, M.J.3
Schaap, O.4
Breedveld, G.J.5
Krieger, E.6
Dekker, M.C.7
Squitieri, F.8
Ibanez, P.9
Joosse, M.10
Van Dongen, J.W.11
Vanacore, N.12
Van Swieten, J.C.13
Brice, A.14
Meco, G.15
Van Duijn, C.M.16
Oostra, B.A.17
Heutink, P.18
-
42
-
-
0035941491
-
Molecular cloning of human and mouse DJ-1 genes and identification of Sp1-dependent activation of the human DJ-1 promoter
-
Taira T, Takahashi K, Kitagawa R, Iguchi-Ariga SM, Ariga H (2001) Molecular cloning of human and mouse DJ-1 genes and identification of Sp1-dependent activation of the human DJ-1 promoter. Gene 263:285-292
-
(2001)
Gene
, vol.263
, pp. 285-292
-
-
Taira, T.1
Takahashi, K.2
Kitagawa, R.3
Iguchi-Ariga, S.M.4
Ariga, H.5
-
43
-
-
0043204995
-
Early-onset Parkinson's disease caused by a compound heterozygous DJ-1 mutation
-
Hague S, Rogaeva E, Hernandez D, Gulick C, Singleton A, Hanson M, Johnson J, Weiser R, Gallardo M, Ravina B, Gwinn-Hardy K, Crawley A, St George-Hyslop PH, Lang AE, Heutink P, Bonifati V, Hardy J, Singleton A (2003) Early-onset Parkinson's disease caused by a compound heterozygous DJ-1 mutation. Ann Neurol 54:271-274
-
(2003)
Ann Neurol
, vol.54
, pp. 271-274
-
-
Hague, S.1
Rogaeva, E.2
Hernandez, D.3
Gulick, C.4
Singleton, A.5
Hanson, M.6
Johnson, J.7
Weiser, R.8
Gallardo, M.9
Ravina, B.10
Gwinn-Hardy, K.11
Crawley, A.12
St George-Hyslop, P.H.13
Lang, A.E.14
Heutink, P.15
Bonifati, V.16
Hardy, J.17
Singleton, A.18
-
44
-
-
0042232353
-
The role of pathogenic DJ-1 mutations in Parkinson's disease
-
Abou-Sleiman PM, Healy DG, Quinn N, Lees AJ, Wood NW (2003) The role of pathogenic DJ-1 mutations in Parkinson's disease. Ann Neurol 54:283-286
-
(2003)
Ann Neurol
, vol.54
, pp. 283-286
-
-
Abou-Sleiman, P.M.1
Healy, D.G.2
Quinn, N.3
Lees, A.J.4
Wood, N.W.5
-
45
-
-
0035860983
-
Complete genomic screen in Parkinson disease: Evidence for multiple genes
-
Scott WK, Nance MA, Watts RL, Hubble JP, Koller WC, Lyons K, Pahwa R, Stern MB, Colcher A, Hiner BC, Jankovic J, Ondo WG, Allen FH Jr, Goetz CG, Small GW, Masterman D, Mastaglia F, Laing NG, Stajich JM, Slotterbeck B, Booze MW, Ribble RC, Rampersaud E, West SG, Gibson RA, Middleton LT, Roses AD, Haines JL, Scott BL, Vance JM, Pericak-Vance MA (2001) Complete genomic screen in Parkinson disease: evidence for multiple genes. JAMA 286:2239-2244
-
(2001)
JAMA
, vol.286
, pp. 2239-2244
-
-
Scott, W.K.1
Nance, M.A.2
Watts, R.L.3
Hubble, J.P.4
Koller, W.C.5
Lyons, K.6
Pahwa, R.7
Stern, M.B.8
Colcher, A.9
Hiner, B.C.10
Jankovic, J.11
Ondo, W.G.12
Allen Jr., F.H.13
Goetz, C.G.14
Small, G.W.15
Masterman, D.16
Mastaglia, F.17
Laing, N.G.18
Stajich, J.M.19
Slotterbeck, B.20
Booze, M.W.21
Ribble, R.C.22
Rampersaud, E.23
West, S.G.24
Gibson, R.A.25
Middleton, L.T.26
Roses, A.D.27
Haines, J.L.28
Scott, B.L.29
Vance, J.M.30
Pericak-Vance, M.A.31
more..
-
46
-
-
18444364221
-
Genome screen to identify susceptibility genes for Parkinson disease in a sample without parkin mutations
-
Pankratz N, Nichols WC, Uniacke SK, Halter C, Rudolph A, Shults C, Conneally PM, Foroud T (2002) Genome screen to identify susceptibility genes for Parkinson disease in a sample without parkin mutations. Am J Hum Genet 71:124-135
-
(2002)
Am J Hum Genet
, vol.71
, pp. 124-135
-
-
Pankratz, N.1
Nichols, W.C.2
Uniacke, S.K.3
Halter, C.4
Rudolph, A.5
Shults, C.6
Conneally, P.M.7
Foroud, T.8
-
47
-
-
0242524434
-
The DJ-1 L166P mutant protein associated with early onset Parkinson's disease is unstable and forms higher order protein complexes
-
Macedo MG, Anar B, Bronner IF, Cannella M, Squitieri F, Bonifati V, Hoogeveen A, Heutink P, Rizzu P (2003) The DJ-1 L166P mutant protein associated with early onset Parkinson's disease is unstable and forms higher order protein complexes. Hum Mol Genet 12:2807-2816
-
(2003)
Hum Mol Genet
, vol.12
, pp. 2807-2816
-
-
Macedo, M.G.1
Anar, B.2
Bronner, I.F.3
Cannella, M.4
Squitieri, F.5
Bonifati, V.6
Hoogeveen, A.7
Heutink, P.8
Rizzu, P.9
-
48
-
-
0141704202
-
L166P mutant DJ-1, causative for recessive Parkinson's disease, is degraded through the ubiquitin-proteasome system
-
Miller DW, Ahmad R, Hague S, Baptista MJ, Canet-Aviles R, McLendon C, Carter DM, Zhu PP, Stadler J, Chandran J, Klinefelter GR, Blackstone C, Cookson MR (2003) L166P mutant DJ-1, causative for recessive Parkinson's disease, is degraded through the ubiquitin-proteasome system. J Biol Chem 278:36588-36595
-
(2003)
J Biol Chem
, vol.278
, pp. 36588-36595
-
-
Miller, D.W.1
Ahmad, R.2
Hague, S.3
Baptista, M.J.4
Canet-Aviles, R.5
McLendon, C.6
Carter, D.M.7
Zhu, P.P.8
Stadler, J.9
Chandran, J.10
Klinefelter, G.R.11
Blackstone, C.12
Cookson, M.R.13
-
49
-
-
0032819023
-
Protein misfolding and degradation in genetic diseases
-
Bross P, Corydon TJ, Andresen BS, Jorgensen MM, Bolund L, Gregersen N (1999) Protein misfolding and degradation in genetic diseases. Hum Mutat 14:186-198
-
(1999)
Hum Mutat
, vol.14
, pp. 186-198
-
-
Bross, P.1
Corydon, T.J.2
Andresen, B.S.3
Jorgensen, M.M.4
Bolund, L.5
Gregersen, N.6
-
50
-
-
0031566231
-
DJ-1, a novel oncogene which transforms mouse NIH3T3 cells in cooperation with ras
-
Nagakubo D, Taira T, Kitaura H, Ikeda M, Tamai K, Iguchi-Ariga SM, Ariga H (1997) DJ-1, a novel oncogene which transforms mouse NIH3T3 cells in cooperation with ras. Biochem Biophys Res Commun 231:509-513
-
(1997)
Biochem Biophys Res Commun
, vol.231
, pp. 509-513
-
-
Nagakubo, D.1
Taira, T.2
Kitaura, H.3
Ikeda, M.4
Tamai, K.5
Iguchi-Ariga, S.M.6
Ariga, H.7
-
51
-
-
0033103726
-
Identification and characterization of a novel protein that regulates RNA-protein interaction
-
Hod Y, Pentyala SN, Whyard TC, El-Maghrabi MR (1999) Identification and characterization of a novel protein that regulates RNA-protein interaction. J Cell Biochem 72:435-444
-
(1999)
J Cell Biochem
, vol.72
, pp. 435-444
-
-
Hod, Y.1
Pentyala, S.N.2
Whyard, T.C.3
El-Maghrabi, M.R.4
-
52
-
-
0036182026
-
Mitochondrial involvement in Parkinson's disease
-
Orth M, Schapira AH (2002) Mitochondrial involvement in Parkinson's disease. Neurochem Int 40:533-541
-
(2002)
Neurochem Int
, vol.40
, pp. 533-541
-
-
Orth, M.1
Schapira, A.H.2
-
53
-
-
0242628430
-
DJ-1 co-localizes with tau inclusions: A link between Parkinsonism and dementia
-
in press
-
Rizzu P, Hinkle DA, Zhucareva V, Bonifati V, Severijnen L-A, Martinez D, Ravid R, Kamphorst W, Eberwine JH, Lee VM-Y, Trojanowski JQ, Heutink P (2003) DJ-1 co-localizes with tau inclusions: a link between Parkinsonism and dementia. Ann Neurol (in press)
-
(2003)
Ann Neurol
-
-
Rizzu, P.1
Hinkle, D.A.2
Zhucareva, V.3
Bonifati, V.4
Severijnen, L.-A.5
Martinez, D.6
Ravid, R.7
Kamphorst, W.8
Eberwine, J.H.9
Lee, V.M.-Y.10
Trojanowski, J.Q.11
Heutink, P.12
-
54
-
-
0031721141
-
Pathologic and biochemical studies of juvenile parkinsonism linked to chromosome 6q
-
Mori H, Kondo T, Yokochi M, Matsumine H, Nakagawa-Hattori Y, Miyake T, Suda K, Mizuno Y (1998) Pathologic and biochemical studies of juvenile parkinsonism linked to chromosome 6q. Neurology 51:890-892
-
(1998)
Neurology
, vol.51
, pp. 890-892
-
-
Mori, H.1
Kondo, T.2
Yokochi, M.3
Matsumine, H.4
Nakagawa-Hattori, Y.5
Miyake, T.6
Suda, K.7
Mizuno, Y.8
-
55
-
-
0035957112
-
Clinical and pathologic abnormalities in a family with parkinsonism and parkin gene mutations
-
Warrenburg BP van de, Lammens M, Lucking CB, Denefle P, Wesseling P, Booij J, Praamstra P, Quinn N, Brice A, Horstink MW (2001) Clinical and pathologic abnormalities in a family with parkinsonism and parkin gene mutations. Neurology 56:555-557
-
(2001)
Neurology
, vol.56
, pp. 555-557
-
-
Van De Warrenburg, B.P.1
Lammens, M.2
Lucking, C.B.3
Denefle, P.4
Wesseling, P.5
Booij, J.6
Praamstra, P.7
Quinn, N.8
Brice, A.9
Horstink, M.W.10
-
56
-
-
0035526282
-
Phenotypic characterisation of autosomal recessive PARK6-linked parkinsonism in three unrelated Italian families
-
Bentivoglio AR, Cortelli P, Valente EM, Ialongo T, Ferraris A, Elia A, Montagna P, Albanese A (2001) Phenotypic characterisation of autosomal recessive PARK6-linked parkinsonism in three unrelated Italian families. Mov Disord 16:999-1006
-
(2001)
Mov Disord
, vol.16
, pp. 999-1006
-
-
Bentivoglio, A.R.1
Cortelli, P.2
Valente, E.M.3
Ialongo, T.4
Ferraris, A.5
Elia, A.6
Montagna, P.7
Albanese, A.8
-
57
-
-
0036895554
-
Clinical and subclinical dopaminergic dysfunction in PARK6-linked parkinsonism: An 18F-dopa PET study
-
Khan NL, Valente EM, Bentivoglio AR, Wood NW, Albanese A, Brooks DJ, Piccini P (2002) Clinical and subclinical dopaminergic dysfunction in PARK6-linked parkinsonism: an 18F-dopa PET study. Ann Neurol 52:849-853
-
(2002)
Ann Neurol
, vol.52
, pp. 849-853
-
-
Khan, N.L.1
Valente, E.M.2
Bentivoglio, A.R.3
Wood, N.W.4
Albanese, A.5
Brooks, D.J.6
Piccini, P.7
-
58
-
-
10744232719
-
Clinical features and neuroimaging of PARK7-linked parkinsonism
-
Dekker M, Bonifati V, van Swieten J et al. (2003) Clinical features and neuroimaging of PARK7-linked parkinsonism. Mov Disord 18:751-757
-
(2003)
Mov Disord
, vol.18
, pp. 751-757
-
-
Dekker, M.1
Bonifati, V.2
Van Swieten, J.3
-
60
-
-
1642618076
-
Chromosome 6-linked autosomal recessive early-onset Parkinsonism: Linkage in European and Algerian families, extension of the clinical spectrum, and evidence of a small homozygous deletion in one family
-
Tassin J, Durr A, de Broucker T, Abbas N, Bonifati V, De Michele G, Bonnet AM, Broussolle E, Pollak P, Vidailhet M, De Mari M, Marconi R, Medjbeur S, Filla A, Meco G, Agid Y, Brice A (1998) Chromosome 6-linked autosomal recessive early-onset Parkinsonism: linkage in European and Algerian families, extension of the clinical spectrum, and evidence of a small homozygous deletion in one family. Am J Hum Genet 63:88-94
-
(1998)
Am J Hum Genet
, vol.63
, pp. 88-94
-
-
Tassin, J.1
Durr, A.2
De Broucker, T.3
Abbas, N.4
Bonifati, V.5
De Michele, G.6
Bonnet, A.M.7
Broussolle, E.8
Pollak, P.9
Vidailhet, M.10
De Mari, M.11
Marconi, R.12
Medjbeur, S.13
Filla, A.14
Meco, G.15
Agid, Y.16
Brice, A.17
-
61
-
-
0038662544
-
Parkin disease: A phenotypic study of a large case series
-
Khan NL, Graham E, Critchley P, Schrag AE, Wood NW, Lees AJ, Bhatia KP, Quinn N (2003) Parkin disease: a phenotypic study of a large case series. Brain 126:1279-1292
-
(2003)
Brain
, vol.126
, pp. 1279-1292
-
-
Khan, N.L.1
Graham, E.2
Critchley, P.3
Schrag, A.E.4
Wood, N.W.5
Lees, A.J.6
Bhatia, K.P.7
Quinn, N.8
-
62
-
-
0035096967
-
Positron emission tomographic analysis of the nigrostriatal dopaminergic system in familial parkinsonism associated with mutations in the parkin gene
-
Hilker R, Klein C, Ghaemi M, Kis B, Strotmann T, Ozelius LJ, Lenz O, Vieregge P, Herholz K, Heiss WD, Pramstaller PP (2001) Positron emission tomographic analysis of the nigrostriatal dopaminergic system in familial parkinsonism associated with mutations in the parkin gene. Ann Neurol 49:367-376
-
(2001)
Ann Neurol
, vol.49
, pp. 367-376
-
-
Hilker, R.1
Klein, C.2
Ghaemi, M.3
Kis, B.4
Strotmann, T.5
Ozelius, L.J.6
Lenz, O.7
Vieregge, P.8
Herholz, K.9
Heiss, W.D.10
Pramstaller, P.P.11
-
63
-
-
0035187302
-
Proteomics-based identification of RS/DJ-1 as a novel circulating tumor antigen in breast cancer
-
Le Naour F, Misek DE, Krause MC, Deneux L, Giordano TJ, Scholl S, Hanash SM (2001) Proteomics-based identification of RS/DJ-1 as a novel circulating tumor antigen in breast cancer. Clin Cancer Res 7:3328-3335
-
(2001)
Clin Cancer Res
, vol.7
, pp. 3328-3335
-
-
Le Naour, F.1
Misek, D.E.2
Krause, M.C.3
Deneux, L.4
Giordano, T.J.5
Scholl, S.6
Hanash, S.M.7
-
64
-
-
0033994455
-
Identification of gel-separated tumor marker proteins by mass spectrometry
-
Bergman AC, Benjamin T, Alaiya A, Waltham M, Sakaguchi K, Franzen B, Linder S, Bergman T, Auer G, Appella E, Wirth PJ, Jornvall H (2000) Identification of gel-separated tumor marker proteins by mass spectrometry. Electrophoresis 21:679-686
-
(2000)
Electrophoresis
, vol.21
, pp. 679-686
-
-
Bergman, A.C.1
Benjamin, T.2
Alaiya, A.3
Waltham, M.4
Sakaguchi, K.5
Franzen, B.6
Linder, S.7
Bergman, T.8
Auer, G.9
Appella, E.10
Wirth, P.J.11
Jornvall, H.12
-
65
-
-
0035987519
-
Detection of cathepsin B up-regulation in neoplastic thyroid tissues by proteomic analysis
-
Srisomsap C, Subhasitanont P, Otto A, Mueller EC, Punyarit P, Wittmann-Liebold B, Svasti J (2002) Detection of cathepsin B up-regulation in neoplastic thyroid tissues by proteomic analysis. Proteomics 2:706-712
-
(2002)
Proteomics
, vol.2
, pp. 706-712
-
-
Srisomsap, C.1
Subhasitanont, P.2
Otto, A.3
Mueller, E.C.4
Punyarit, P.5
Wittmann-Liebold, B.6
Svasti, J.7
-
66
-
-
0036778378
-
Alteration of intracellular structure and function of glyceraldehyde-3-phosphate dehydrogenase: A common phenotype of neurodegenerative disorders?
-
Mazzola JL, Sirover MA (2002) Alteration of intracellular structure and function of glyceraldehyde-3-phosphate dehydrogenase: a common phenotype of neurodegenerative disorders? Neurotoxicology 23:603-609
-
(2002)
Neurotoxicology
, vol.23
, pp. 603-609
-
-
Mazzola, J.L.1
Sirover, M.A.2
-
67
-
-
0031968628
-
Nuclear localization of overexpressed glyceraldehyde-3-phosphate dehydrogenase in cultured cerebellar neurons undergoing apoptosis
-
Ishitani R, Tanaka M, Sunaga K, Katsube N, Chuang DM (1998) Nuclear localization of overexpressed glyceraldehyde-3-phosphate dehydrogenase in cultured cerebellar neurons undergoing apoptosis. Mol Pharmacol 53:701-707
-
(1998)
Mol Pharmacol
, vol.53
, pp. 701-707
-
-
Ishitani, R.1
Tanaka, M.2
Sunaga, K.3
Katsube, N.4
Chuang, D.M.5
-
68
-
-
0035800214
-
GAPDH knockdown rescues mesencephalic dopaminergic neurons from MPP+-induced apoptosis
-
Fukuhara Y, Takeshima T, Kashiwaya Y, Shimoda K, Ishitani R, Nakashima K (2001) GAPDH knockdown rescues mesencephalic dopaminergic neurons from MPP+-induced apoptosis. Neuroreport 12:2049-2052
-
(2001)
Neuroreport
, vol.12
, pp. 2049-2052
-
-
Fukuhara, Y.1
Takeshima, T.2
Kashiwaya, Y.3
Shimoda, K.4
Ishitani, R.5
Nakashima, K.6
-
69
-
-
0033756901
-
Increased caspase 3 and Bax immunoreactivity accompany nuclear GAPDH translocation and neuronal apoptosis in Parkinson's disease
-
Tatton NA (2000) Increased caspase 3 and Bax immunoreactivity accompany nuclear GAPDH translocation and neuronal apoptosis in Parkinson's disease. Exp Neurol 166:29-43
-
(2000)
Exp Neurol
, vol.166
, pp. 29-43
-
-
Tatton, N.A.1
-
70
-
-
0035186283
-
Parallel and comparative analysis of the proteome and transcriptome of sorbic acid-stressed Saccharomyces cerevisiae
-
Nobel H de, Lawrie L, Brul S, Klis F, Davis M, Alloush H, Coote P (2001) Parallel and comparative analysis of the proteome and transcriptome of sorbic acid-stressed Saccharomyces cerevisiae. Yeast 18:1413-1428
-
(2001)
Yeast
, vol.18
, pp. 1413-1428
-
-
De Nobel, H.1
Lawrie, L.2
Brul, S.3
Klis, F.4
Davis, M.5
Alloush, H.6
Coote, P.7
-
71
-
-
0032112350
-
SP22: A novel fertility protein from a highly conserved gene family
-
Welch JE, Barbee RR, Roberts NL, Suarez JD, Klinefelter GR (1998) SP22: a novel fertility protein from a highly conserved gene family. J Androl 19:385-393
-
(1998)
J Androl
, vol.19
, pp. 385-393
-
-
Welch, J.E.1
Barbee, R.R.2
Roberts, N.L.3
Suarez, J.D.4
Klinefelter, G.R.5
-
72
-
-
0032552851
-
Molecular cloning and expression of rat contraception associated protein 1 (CAP1), a protein putatively involved in fertilization
-
Wagenfeld A, Gromoll J, Cooper TG (1998) Molecular cloning and expression of rat contraception associated protein 1 (CAP1), a protein putatively involved in fertilization. Biochem Biophys Res Commun 251:545-549
-
(1998)
Biochem Biophys Res Commun
, vol.251
, pp. 545-549
-
-
Wagenfeld, A.1
Gromoll, J.2
Cooper, T.G.3
-
73
-
-
0033971318
-
Identification of RS as a flagellar and head sperm protein
-
Whyard TC, Cheung W, Sheynkin Y, Waltzer WC, Hod Y (2000) Identification of RS as a flagellar and head sperm protein. Mol Reprod Dev 55:189-196
-
(2000)
Mol Reprod Dev
, vol.55
, pp. 189-196
-
-
Whyard, T.C.1
Cheung, W.2
Sheynkin, Y.3
Waltzer, W.C.4
Hod, Y.5
-
74
-
-
0035813135
-
DJ-1 positively regulates the androgen receptor by impairing the binding of PIASx alpha to the receptor
-
Takahashi K, Taira T, Niki T, Seino C, Iguchi-Ariga SM, Ariga H (2001) DJ-1 positively regulates the androgen receptor by impairing the binding of PIASx alpha to the receptor. J Biol Chem 276:37556-37563
-
(2001)
J Biol Chem
, vol.276
, pp. 37556-37563
-
-
Takahashi, K.1
Taira, T.2
Niki, T.3
Seino, C.4
Iguchi-Ariga, S.M.5
Ariga, H.6
-
75
-
-
0033525191
-
A testis-specific androgen receptor coregulator that belongs to a novel family of nuclear proteins
-
Moilanen AM, Karvonen U, Poukka H, Yan W, Toppari J, Janne OA, Palvimo JJ (1999) A testis-specific androgen receptor coregulator that belongs to a novel family of nuclear proteins. J Biol Chem 274:3700-3704
-
(1999)
J Biol Chem
, vol.274
, pp. 3700-3704
-
-
Moilanen, A.M.1
Karvonen, U.2
Poukka, H.3
Yan, W.4
Toppari, J.5
Janne, O.A.6
Palvimo, J.J.7
-
76
-
-
0034530046
-
ARIP3 (androgen receptor-interacting protein 3) and other PIAS (protein inhibitor of activated STAT) proteins differ in their ability to modulate steroid receptor-dependent transcriptional activation
-
Kotaja N, Aittomaki S, Silvennoinen O, Palvimo JJ, Janne OA (2000) ARIP3 (androgen receptor-interacting protein 3) and other PIAS (protein inhibitor of activated STAT) proteins differ in their ability to modulate steroid receptor-dependent transcriptional activation. Mol Endocrinol 14:1986-2000
-
(2000)
Mol Endocrinol
, vol.14
, pp. 1986-2000
-
-
Kotaja, N.1
Aittomaki, S.2
Silvennoinen, O.3
Palvimo, J.J.4
Janne, O.A.5
-
77
-
-
0036291475
-
PIAS proteins modulate transcription factors by functioning as SUMO-1 ligases
-
Kotaja N, Karvonen U, Janne OA, Palvimo JJ (2002) PIAS proteins modulate transcription factors by functioning as SUMO-1 ligases. Mol Cell Biol 22:5222-5234
-
(2002)
Mol Cell Biol
, vol.22
, pp. 5222-5234
-
-
Kotaja, N.1
Karvonen, U.2
Janne, O.A.3
Palvimo, J.J.4
-
78
-
-
0037291493
-
DJBP: A novel DJ-1-binding protein, negatively regulates the androgen receptor by recruiting histone deacetylase complex, and DJ-1 antagonizes this inhibition by abrogation of this complex
-
Niki T, Takahashi-Niki K, Taira T, Iguchi-Ariga SM, Ariga H (2003) DJBP: a novel DJ-1-binding protein, negatively regulates the androgen receptor by recruiting histone deacetylase complex, and DJ-1 antagonizes this inhibition by abrogation of this complex. Mol Cancer Res 1:247-261
-
(2003)
Mol Cancer Res
, vol.1
, pp. 247-261
-
-
Niki, T.1
Takahashi-Niki, K.2
Taira, T.3
Iguchi-Ariga, S.M.4
Ariga, H.5
-
79
-
-
0034731301
-
Identification and characterization of a SUMO-1 conjugation system that modifies neuronal calcium/calmodulin-dependent protein kinase II in Drosophila melanogaster
-
Long X, Griffith LC (2000) Identification and characterization of a SUMO-1 conjugation system that modifies neuronal calcium/calmodulin-dependent protein kinase II in Drosophila melanogaster. J Biol Chem 275:40765-40776
-
(2000)
J Biol Chem
, vol.275
, pp. 40765-40776
-
-
Long, X.1
Griffith, L.C.2
-
80
-
-
0036850456
-
Genetic modulation of polyglutamine toxicity by protein conjugation pathways in Drosophila
-
Chan HY, Warrick JM, Andriola I, Merry D, Bonini NM (2002) Genetic modulation of polyglutamine toxicity by protein conjugation pathways in Drosophila. Hum Mol Genet 11:2895-2904
-
(2002)
Hum Mol Genet
, vol.11
, pp. 2895-2904
-
-
Chan, H.Y.1
Warrick, J.M.2
Andriola, I.3
Merry, D.4
Bonini, N.M.5
-
81
-
-
0036237383
-
Versatile protein tag, SUMO: Its enzymology and biological function
-
Kim KI, Baek SH, Chung CH (2002) Versatile protein tag, SUMO: its enzymology and biological function. J Cell Physiol 191:257-268
-
(2002)
J Cell Physiol
, vol.191
, pp. 257-268
-
-
Kim, K.I.1
Baek, S.H.2
Chung, C.H.3
-
82
-
-
0036296111
-
Enhanced SUMOylation in polyglutamine diseases
-
Ueda H, Goto J, Hashida H, Lin X, Oyanagi K, Kawano H, Zoghbi HY, Kanazawa I, Okazawa H (2002) Enhanced SUMOylation in polyglutamine diseases. Biochem Biophys Res Commun 293:307-313
-
(2002)
Biochem Biophys Res Commun
, vol.293
, pp. 307-313
-
-
Ueda, H.1
Goto, J.2
Hashida, H.3
Lin, X.4
Oyanagi, K.5
Kawano, H.6
Zoghbi, H.Y.7
Kanazawa, I.8
Okazawa, H.9
-
83
-
-
0035692636
-
DJ-1 is an indicator for endogenous reactive oxygen species elicited by endotoxin
-
Mitsumoto A, Nakagawa Y (2001) DJ-1 is an indicator for endogenous reactive oxygen species elicited by endotoxin. Free Radic Res 35:885-893
-
(2001)
Free Radic Res
, vol.35
, pp. 885-893
-
-
Mitsumoto, A.1
Nakagawa, Y.2
-
84
-
-
0034906096
-
Oxidized forms of peroxiredoxins and DJ-1 on two-dimensional gels increased in response to sublethal levels of paraquat
-
Mitsumoto A, Nakagawa Y, Takeuchi A, Okawa K, Iwamatsu A, Takanezawa Y (2001) Oxidized forms of peroxiredoxins and DJ-1 on two-dimensional gels increased in response to sublethal levels of paraquat. Free Radic Res 35:301-310
-
(2001)
Free Radic Res
, vol.35
, pp. 301-310
-
-
Mitsumoto, A.1
Nakagawa, Y.2
Takeuchi, A.3
Okawa, K.4
Iwamatsu, A.5
Takanezawa, Y.6
-
85
-
-
0035151514
-
Low external pH induces HOG1-dependent changes in the organization of the Saccharomyces cerevisiae cell wall
-
Kapteyn JC, ter Riet B, Vink E, Blad S, De Nobel H, Van Den Ende H, Klis FM (2001) Low external pH induces HOG1-dependent changes in the organization of the Saccharomyces cerevisiae cell wall. Mol Microbiol 39:469-479
-
(2001)
Mol Microbiol
, vol.39
, pp. 469-479
-
-
Kapteyn, J.C.1
Ter Riet, B.2
Vink, E.3
Blad, S.4
De Nobel, H.5
Van Den Ende, H.6
Klis, F.M.7
-
86
-
-
0346736509
-
Misfolded proteins are competent to mediate a subset of the responses to heat shock in Saccharomyces cerevisiae
-
Trotter EW, Kao CM, Berenfeld L, Botstein D, Petsko GA, Gray JV (2002) Misfolded proteins are competent to mediate a subset of the responses to heat shock in Saccharomyces cerevisiae. J Biol Chem 277:44817-4825
-
(2002)
J Biol Chem
, vol.277
, pp. 44817-44825
-
-
Trotter, E.W.1
Kao, C.M.2
Berenfeld, L.3
Botstein, D.4
Petsko, G.A.5
Gray, J.V.6
-
87
-
-
0037453026
-
The 1.6-A crystal structure of the class of chaperones represented by Escherichia coli Hsp31 reveals a putative catalytic triad
-
Quigley PM, Korotkov K, Baneyx F, Hol WG (2003) The 1.6-A crystal structure of the class of chaperones represented by Escherichia coli Hsp31 reveals a putative catalytic triad. Proc Natl Acad Sci U S A 100:3137-3142
-
(2003)
Proc Natl Acad Sci U S A
, vol.100
, pp. 3137-3142
-
-
Quigley, P.M.1
Korotkov, K.2
Baneyx, F.3
Hol, W.G.4
-
88
-
-
0242497815
-
Crystal structures of human DJ-1 and Escherichia coli Hsp31 that share an evolutionarily conserved domain
-
Lee SJ, Kim SJ, Kim IK, Ko J, Jeong CS, Kim GH, Park C, Kang SO, Suh PG, Lee HS, Cha SS (2003) Crystal structures of human DJ-1 and Escherichia coli Hsp31 that share an evolutionarily conserved domain. J Biol Chem 278:44552-44559
-
(2003)
J Biol Chem
, vol.278
, pp. 44552-44559
-
-
Lee, S.J.1
Kim, S.J.2
Kim, I.K.3
Ko, J.4
Jeong, C.S.5
Kim, G.H.6
Park, C.7
Kang, S.O.8
Suh, P.G.9
Lee, H.S.10
Cha, S.S.11
-
89
-
-
0037096193
-
The relationship between oxidative/nitrative stress and pathological inclusions in Alzheimer's and Parkinson's diseases
-
Giasson BI, Ischiropoulos H, Lee VM, Trojanowski JQ (2002) The relationship between oxidative/nitrative stress and pathological inclusions in Alzheimer's and Parkinson's diseases. Free Radic Biol Med 32:1264-1275
-
(2002)
Free Radic Biol Med
, vol.32
, pp. 1264-1275
-
-
Giasson, B.I.1
Ischiropoulos, H.2
Lee, V.M.3
Trojanowski, J.Q.4
-
90
-
-
0037047311
-
Effect of wild-type or mutant Parkin on oxidative damage, nitric oxide, antioxidant defenses, and the proteasome
-
Hyun DH, Lee M, Hattori N, Kubo S, Mizuno Y, Halliwell B, Jenner P (2002) Effect of wild-type or mutant Parkin on oxidative damage, nitric oxide, antioxidant defenses, and the proteasome. J Biol Chem 277:28572-28577
-
(2002)
J Biol Chem
, vol.277
, pp. 28572-28577
-
-
Hyun, D.H.1
Lee, M.2
Hattori, N.3
Kubo, S.4
Mizuno, Y.5
Halliwell, B.6
Jenner, P.7
-
91
-
-
0037192865
-
Alpha-Synuclein protects against oxidative stress via inactivation of the c-Jun N-terminal kinase stress-signaling pathway in neuronal cells
-
Hashimoto M, Hsu LJ, Rockenstein E, Takenouchi T, Mallory M, Masliah E (2002) alpha-Synuclein protects against oxidative stress via inactivation of the c-Jun N-terminal kinase stress-signaling pathway in neuronal cells. J Biol Chem 277:11465-11472
-
(2002)
J Biol Chem
, vol.277
, pp. 11465-11472
-
-
Hashimoto, M.1
Hsu, L.J.2
Rockenstein, E.3
Takenouchi, T.4
Mallory, M.5
Masliah, E.6
-
92
-
-
0036254972
-
Oxidative stress, spermatogenesis and fertility
-
Maiorino M, Ursini F (2002) Oxidative stress, spermatogenesis and fertility. Biol Chem 383:591-597
-
(2002)
Biol Chem
, vol.383
, pp. 591-597
-
-
Maiorino, M.1
Ursini, F.2
-
93
-
-
0343627933
-
Possible redox regulation of sperm motility activation
-
Aitken RJ (2000) Possible redox regulation of sperm motility activation. J Androl 21:491-496
-
(2000)
J Androl
, vol.21
, pp. 491-496
-
-
Aitken, R.J.1
-
95
-
-
0034644522
-
Signal transduction by the JNK group of MAP kinases
-
Davis RJ (2000) Signal transduction by the JNK group of MAP kinases. Cell 103:239-252
-
(2000)
Cell
, vol.103
, pp. 239-252
-
-
Davis, R.J.1
-
96
-
-
0035964358
-
Gene transfer of the JNK interacting protein-1 protects dopaminergic neurons in the MPTP model of Parkinson's disease
-
Xia XG, Harding T, Weller M, Bieneman A, Uney JB, Schulz JB (2001) Gene transfer of the JNK interacting protein-1 protects dopaminergic neurons in the MPTP model of Parkinson's disease. Proc Natl Acad Sci U S A 98:10433-10438
-
(2001)
Proc Natl Acad Sci U S A
, vol.98
, pp. 10433-10438
-
-
Xia, X.G.1
Harding, T.2
Weller, M.3
Bieneman, A.4
Uney, J.B.5
Schulz, J.B.6
-
97
-
-
0042232039
-
Crystal structure of human DJ-1, a protein associated with early-onset Parkinson's diseases
-
Tao X, Tong L (2003) Crystal structure of human DJ-1, a protein associated with early-onset Parkinson's diseases. J Biol Chem 278:31372-31379
-
(2003)
J Biol Chem
, vol.278
, pp. 31372-31379
-
-
Tao, X.1
Tong, L.2
-
98
-
-
0042232029
-
The crystal structure of DJ-1, a protein related to male fertility and Parkinson's disease
-
Honbou K, Suzuki NN, Horiuchi M, Niki T, Taira T, Ariga H, Inagaki F (2003) The crystal structure of DJ-1, a protein related to male fertility and Parkinson's disease. J Biol Chem 278:31380-31384
-
(2003)
J Biol Chem
, vol.278
, pp. 31380-31384
-
-
Honbou, K.1
Suzuki, N.N.2
Horiuchi, M.3
Niki, T.4
Taira, T.5
Ariga, H.6
Inagaki, F.7
-
99
-
-
0042130551
-
The 1.1-A resolution crystal structure of DJ-1, the protein mutated in autosomal recessive early onset Parkinson's disease
-
Wilson MA, Collins JL, Hod Y, Ringe D, Petsko GA (2003) The 1.1-A resolution crystal structure of DJ-1, the protein mutated in autosomal recessive early onset Parkinson's disease. Proc Natl Acad Sci U S A 100:9256-9261
-
(2003)
Proc Natl Acad Sci U S A
, vol.100
, pp. 9256-9261
-
-
Wilson, M.A.1
Collins, J.L.2
Hod, Y.3
Ringe, D.4
Petsko, G.A.5
-
100
-
-
0042063899
-
Crystal structure of DJ-1/RS and implication on familial Parkinson's disease
-
Huai Q, Sun Y, Wang H, Chin LS, Li L, Robinson H, Ke H (2003) Crystal structure of DJ-1/RS and implication on familial Parkinson's disease. FEBS Lett 549:171-175
-
(2003)
FEBS Lett
, vol.549
, pp. 171-175
-
-
Huai, Q.1
Sun, Y.2
Wang, H.3
Chin, L.S.4
Li, L.5
Robinson, H.6
Ke, H.7
-
101
-
-
0033617146
-
A temperature-dependent switch from chaperone to protease in a widely conserved heat shock protein
-
Spiess C, Beil A, Ehrmann M (1999) A temperature-dependent switch from chaperone to protease in a widely conserved heat shock protein. Cell 97:339-347
-
(1999)
Cell
, vol.97
, pp. 339-347
-
-
Spiess, C.1
Beil, A.2
Ehrmann, M.3
-
102
-
-
0032924105
-
Chaperone-mediated protein folding
-
Fink AL (1999) Chaperone-mediated protein folding. Physiol Rev 79:425-449
-
(1999)
Physiol Rev
, vol.79
, pp. 425-449
-
-
Fink, A.L.1
-
103
-
-
0032727617
-
Suppression of polyglutamine-mediated neurodegeneration in Drosophila by the molecular chaperone HSP70
-
Warrick JM, Chan HY, Gray-Board GL, Chai Y, Paulson HL, Bonini NM (1999) Suppression of polyglutamine-mediated neurodegeneration in Drosophila by the molecular chaperone HSP70. Nat Genet 23:425-428
-
(1999)
Nat Genet
, vol.23
, pp. 425-428
-
-
Warrick, J.M.1
Chan, H.Y.2
Gray-Board, G.L.3
Chai, Y.4
Paulson, H.L.5
Bonini, N.M.6
-
104
-
-
0034597833
-
Identification of genes that modify ataxin-1-induced neurodegeneration
-
Fernandez-Funez P, Nino-Rosales ML, de Gouyon B, She WC, Luchak JM, Martinez P, Turiegano E, Benito J, Capovilla M, Skinner PJ, McCall A, Canal I, Orr HT, Zoghbi HY, Botas J (2000) Identification of genes that modify ataxin-1-induced neurodegeneration. Nature 408:101-106
-
(2000)
Nature
, vol.408
, pp. 101-106
-
-
Fernandez-Funez, P.1
Nino-Rosales, M.L.2
De Gouyon, B.3
She, W.C.4
Luchak, J.M.5
Martinez, P.6
Turiegano, E.7
Benito, J.8
Capovilla, M.9
Skinner, P.J.10
McCall, A.11
Canal, I.12
Orr, H.T.13
Zoghbi, H.Y.14
Botas, J.15
-
105
-
-
0035394668
-
Over-expression of inducible HSP70 chaperone suppresses neuropathology and improves motor function in SCA1 mice
-
Cummings CJ, Sun Y, Opal P, Antalffy B, Mestril R, Orr HT, Dillmann WH, Zoghbi HY (2001) Over-expression of inducible HSP70 chaperone suppresses neuropathology and improves motor function in SCA1 mice. Hum Mol Genet 10:1511-1518
-
(2001)
Hum Mol Genet
, vol.10
, pp. 1511-1518
-
-
Cummings, C.J.1
Sun, Y.2
Opal, P.3
Antalffy, B.4
Mestril, R.5
Orr, H.T.6
Dillmann, W.H.7
Zoghbi, H.Y.8
-
106
-
-
0036468432
-
Chaperone suppression of alpha-synuclein toxicity in a Drosophila model for Parkinson's disease
-
Auluck PK, Chan HY, Trojanowski JQ, Lee VM, Bonini NM (2002) Chaperone suppression of alpha-synuclein toxicity in a Drosophila model for Parkinson's disease. Science 295:865-868
-
(2002)
Science
, vol.295
, pp. 865-868
-
-
Auluck, P.K.1
Chan, H.Y.2
Trojanowski, J.Q.3
Lee, V.M.4
Bonini, N.M.5
-
107
-
-
0036635755
-
DJ-1, a target protein for an endocrine disrupter, participates in the fertilization in mice
-
Okada M, Matsumoto K, Niki T, Taira T, Iguchi-Ariga SM, Ariga H (2002) DJ-1, a target protein for an endocrine disrupter, participates in the fertilization in mice. Biol Pharm Bull 25:853-856
-
(2002)
Biol Pharm Bull
, vol.25
, pp. 853-856
-
-
Okada, M.1
Matsumoto, K.2
Niki, T.3
Taira, T.4
Iguchi-Ariga, S.M.5
Ariga, H.6
-
108
-
-
0031951197
-
A susceptibility locus for Parkinson's disease maps to chromosome 2p13
-
Gasser T, Muller-Myhsok B, Wszolek ZK, Oehlmann R, Calne DB, Bonifati V, Bereznai B, Fabrizio E, Vieregge P, Horstmann RD (1998) A susceptibility locus for Parkinson's disease maps to chromosome 2p13. Nat Genet 18:262-265
-
(1998)
Nat Genet
, vol.18
, pp. 262-265
-
-
Gasser, T.1
Muller-Myhsok, B.2
Wszolek, Z.K.3
Oehlmann, R.4
Calne, D.B.5
Bonifati, V.6
Bereznai, B.7
Fabrizio, E.8
Vieregge, P.9
Horstmann, R.D.10
-
109
-
-
0032911910
-
A chromosome 4p haplotype segregating with Parkinson's disease and postural tremor
-
Farrer M, Gwinn-Hardy K, Muenter M, DeVrieze FW, Crook R, Perez-Tur J, Lincoln S, Maraganore D, Adler C, Newman S, MacElwee K, McCarthy P, Miller C, Waters C, Hardy J (1999) A chromosome 4p haplotype segregating with Parkinson's disease and postural tremor. Hum Mol Genet 8:81-85
-
(1999)
Hum Mol Genet
, vol.8
, pp. 81-85
-
-
Farrer, M.1
Gwinn-Hardy, K.2
Muenter, M.3
DeVrieze, F.W.4
Crook, R.5
Perez-Tur, J.6
Lincoln, S.7
Maraganore, D.8
Adler, C.9
Newman, S.10
MacElwee, K.11
McCarthy, P.12
Miller, C.13
Waters, C.14
Hardy, J.15
-
110
-
-
0036196860
-
A new locus for Parkinson's disease (PARK8) maps to chromosome 12p11.2-q13.1
-
Funayama M, Hasegawa K, Kowa H, Saito M, Tsuji S, Obata F (2002) A new locus for Parkinson's disease (PARK8) maps to chromosome 12p11.2-q13.1. Ann Neurol 51:296-301
-
(2002)
Ann Neurol
, vol.51
, pp. 296-301
-
-
Funayama, M.1
Hasegawa, K.2
Kowa, H.3
Saito, M.4
Tsuji, S.5
Obata, F.6
-
111
-
-
0037226797
-
Mutations in NR4A2 associated with familial Parkinson disease
-
Le WD, Xu P, Jankovic J, Jiang H, Appel SH, Smith RG, Vassilatis DK (2003) Mutations in NR4A2 associated with familial Parkinson disease. Nat Genet 33:85-89
-
(2003)
Nat Genet
, vol.33
, pp. 85-89
-
-
Le, W.D.1
Xu, P.2
Jankovic, J.3
Jiang, H.4
Appel, S.H.5
Smith, R.G.6
Vassilatis, D.K.7
-
112
-
-
0242300619
-
Alpha-Synuclein locus triplication causes Parkinson's disease
-
Singleton AB, Farrer M, Johnson J, Singleton A, Hague S, Kachergus J, Hulihan M, Peuralinna T, Dutra A, Nussbaum R, Lincoln S, Crawley A, Hanson M, Maraganore D, Adler C, Cookson MR, Muenter M, Baptista M, Miller D, Blancato J, Hardy J, Gwinn-Hardy K (2003) alpha-Synuclein locus triplication causes Parkinson's disease. Science 302:841
-
(2003)
Science
, vol.302
, pp. 841
-
-
Singleton, A.B.1
Farrer, M.2
Johnson, J.3
Singleton, A.4
Hague, S.5
Kachergus, J.6
Hulihan, M.7
Peuralinna, T.8
Dutra, A.9
Nussbaum, R.10
Lincoln, S.11
Crawley, A.12
Hanson, M.13
Maraganore, D.14
Adler, C.15
Cookson, M.R.16
Muenter, M.17
Baptista, M.18
Miller, D.19
Blancato, J.20
Hardy, J.21
Gwinn-Hardy, K.22
more..
|