-
4
-
-
0017820387
-
The morphology of cirrhosis. Recommendations on definition, nomenclature, and classification by a working group sponsored by the World Health Organization
-
Anthony PP, Ishak KG, Nayak NC, et al. The morphology of cirrhosis. Recommendations on definition, nomenclature, and classification by a working group sponsored by the World Health Organization. J Clin Pathol 1978, 31(5):395-414.
-
(1978)
J Clin Pathol
, vol.31
, Issue.5
, pp. 395-414
-
-
Anthony, P.P.1
Ishak, K.G.2
Nayak, N.C.3
-
5
-
-
84893141250
-
Hepatic stellate cells and liver fibrosis
-
Puche JE, Saiman Y, Friedman SL Hepatic stellate cells and liver fibrosis. Compr Physiol 2013, 3(4):1473-1492.
-
(2013)
Compr Physiol
, vol.3
, Issue.4
, pp. 1473-1492
-
-
Puche, J.E.1
Saiman, Y.2
Friedman, S.L.3
-
6
-
-
38549159026
-
Cellular and molecular mechanisms of fibrosis
-
Wynn TA Cellular and molecular mechanisms of fibrosis. J Pathol 2008, 214(2):199-210.
-
(2008)
J Pathol
, vol.214
, Issue.2
, pp. 199-210
-
-
Wynn, T.A.1
-
7
-
-
35948954244
-
Hepatic stellate cells: protean, multifunctional, and enigmatic cells of the liver
-
Friedman SL Hepatic stellate cells: protean, multifunctional, and enigmatic cells of the liver. Physiol Rev 2008, 88(1):125-172.
-
(2008)
Physiol Rev
, vol.88
, Issue.1
, pp. 125-172
-
-
Friedman, S.L.1
-
8
-
-
84905970880
-
Origin of myofibroblasts in the fibrotic liver in mice
-
Iwaisako K, Jiang C, Zhang M, et al. Origin of myofibroblasts in the fibrotic liver in mice. Proc Natl Acad Sci USA 2014, 111(32):E3297-E3305.
-
(2014)
Proc Natl Acad Sci USA
, vol.111
, Issue.32
, pp. E3297-E3305
-
-
Iwaisako, K.1
Jiang, C.2
Zhang, M.3
-
9
-
-
84888339170
-
Fate tracing reveals hepatic stellate cells as dominant contributors to liver fibrosis independent of its aetiology
-
Mederacke I, Hsu CC, Troeger JS, et al. Fate tracing reveals hepatic stellate cells as dominant contributors to liver fibrosis independent of its aetiology. Nat Commun 2013, 4:2823.
-
(2013)
Nat Commun
, vol.4
, pp. 2823
-
-
Mederacke, I.1
Hsu, C.C.2
Troeger, J.S.3
-
10
-
-
84878527104
-
Smoothened is a master regulator of adult liver repair
-
Michelotti GA, Xie G, Swiderska M, et al. Smoothened is a master regulator of adult liver repair. J Clin Invest 2013, 123(6):2380-2394.
-
(2013)
J Clin Invest
, vol.123
, Issue.6
, pp. 2380-2394
-
-
Michelotti, G.A.1
Xie, G.2
Swiderska, M.3
-
11
-
-
0005495410
-
Capillarization of hepatic sinusoids in man
-
Schaffner F, Poper H Capillarization of hepatic sinusoids in man. Gastroenterology 1963, 44:239-242.
-
(1963)
Gastroenterology
, vol.44
, pp. 239-242
-
-
Schaffner, F.1
Poper, H.2
-
12
-
-
84928209791
-
Liver sinusoidal endothelial cells in hepatic fibrosis
-
DeLeve LD Liver sinusoidal endothelial cells in hepatic fibrosis. Hepatology 2014, http://dx.doi.org/10.1002/hep.27376.
-
(2014)
Hepatology
-
-
DeLeve, L.D.1
-
13
-
-
0033945689
-
Liver pathology: cirrhosis, hepatitis, and primary liver tumors. Update and diagnostic problems
-
Ferrell L Liver pathology: cirrhosis, hepatitis, and primary liver tumors. Update and diagnostic problems. Mod Pathol 2000, 13(6):679-704.
-
(2000)
Mod Pathol
, vol.13
, Issue.6
, pp. 679-704
-
-
Ferrell, L.1
-
14
-
-
84864346121
-
Fibrosis-dependent mechanisms of hepatocarcinogenesis
-
Zhang DY, Friedman SL Fibrosis-dependent mechanisms of hepatocarcinogenesis. Hepatology 2012, 56(2):769-775.
-
(2012)
Hepatology
, vol.56
, Issue.2
, pp. 769-775
-
-
Zhang, D.Y.1
Friedman, S.L.2
-
15
-
-
0033996891
-
Etiology of hepatocellular carcinoma in Italian patients with and without cirrhosis
-
Chiesa R, Donato F, Tagger A, et al. Etiology of hepatocellular carcinoma in Italian patients with and without cirrhosis. Cancer Epidemiol Biomarkers Prev 2000, 9(2):213-216.
-
(2000)
Cancer Epidemiol Biomarkers Prev
, vol.9
, Issue.2
, pp. 213-216
-
-
Chiesa, R.1
Donato, F.2
Tagger, A.3
-
16
-
-
0025835071
-
Hepatocellular carcinoma. A worldwide problem and the major risk factors
-
Simonetti RG, Camma C, Fiorello F, et al. Hepatocellular carcinoma. A worldwide problem and the major risk factors. Dig Dis Sci 1991, 36(7):962-972.
-
(1991)
Dig Dis Sci
, vol.36
, Issue.7
, pp. 962-972
-
-
Simonetti, R.G.1
Camma, C.2
Fiorello, F.3
-
17
-
-
84555179609
-
Extracellular matrix degradation and remodeling in development and disease
-
Lu P, Takai K, Weaver VM, Werb Z Extracellular matrix degradation and remodeling in development and disease. Cold Spring Harb Perspect Biol 2011, 3:12.
-
(2011)
Cold Spring Harb Perspect Biol
, vol.3
, pp. 12
-
-
Lu, P.1
Takai, K.2
Weaver, V.M.3
Werb, Z.4
-
18
-
-
0032952079
-
Expression patterns of matrix metalloproteinases and their inhibitors in parenchymal and non-parenchymal cells of rat liver: regulation by TNF-alpha and TGF-beta1
-
Knittel T, Mehde M, Kobold D, et al. Expression patterns of matrix metalloproteinases and their inhibitors in parenchymal and non-parenchymal cells of rat liver: regulation by TNF-alpha and TGF-beta1. J Hepatol 1999, 30(1):48-60.
-
(1999)
J Hepatol
, vol.30
, Issue.1
, pp. 48-60
-
-
Knittel, T.1
Mehde, M.2
Kobold, D.3
-
19
-
-
0024431505
-
Lipocytes from normal rat liver release a neutral metalloproteinase that degrades basement membrane (type IV) collagen
-
Arthur MJ, Friedman SL, Roll FJ, Bissell DM Lipocytes from normal rat liver release a neutral metalloproteinase that degrades basement membrane (type IV) collagen. J Clin Invest 1989, 84(4):1076-1085.
-
(1989)
J Clin Invest
, vol.84
, Issue.4
, pp. 1076-1085
-
-
Arthur, M.J.1
Friedman, S.L.2
Roll, F.J.3
Bissell, D.M.4
-
21
-
-
0034808233
-
Matrix as a modulator of hepatic fibrogenesis
-
Schuppan D, Ruehl M, Somasundaram R, Hahn EG Matrix as a modulator of hepatic fibrogenesis. Semin Liver Dis 2001, 21(3):351-372.
-
(2001)
Semin Liver Dis
, vol.21
, Issue.3
, pp. 351-372
-
-
Schuppan, D.1
Ruehl, M.2
Somasundaram, R.3
Hahn, E.G.4
-
22
-
-
0001520008
-
Hepatic lipocytes: the principal collagen-producing cells of normal rat liver
-
Friedman SL, Roll FJ, Boyles J, Bissell DM Hepatic lipocytes: the principal collagen-producing cells of normal rat liver. Proc Natl Acad Sci USA 1985, 82(24):8681-8685.
-
(1985)
Proc Natl Acad Sci USA
, vol.82
, Issue.24
, pp. 8681-8685
-
-
Friedman, S.L.1
Roll, F.J.2
Boyles, J.3
Bissell, D.M.4
-
23
-
-
84921522273
-
Connective tissue growth factor and integrin alphavbeta6: a new pair of regulators critical for ductular reaction and biliary fibrosis
-
Pi L, Robinson PM, Jorgensen M, et al. Connective tissue growth factor and integrin alphavbeta6: a new pair of regulators critical for ductular reaction and biliary fibrosis. Hepatology 2014, http://dx.doi.org/10.1002/hep.27425.
-
(2014)
Hepatology
-
-
Pi, L.1
Robinson, P.M.2
Jorgensen, M.3
-
24
-
-
55849135600
-
Hedgehog signaling regulates epithelial-mesenchymal transition during biliary fibrosis in rodents and humans
-
Omenetti A, Porrello A, Jung Y, et al. Hedgehog signaling regulates epithelial-mesenchymal transition during biliary fibrosis in rodents and humans. J Clin Invest 2008, 118(10):3331-3342.
-
(2008)
J Clin Invest
, vol.118
, Issue.10
, pp. 3331-3342
-
-
Omenetti, A.1
Porrello, A.2
Jung, Y.3
-
25
-
-
36348984906
-
ADAM metallopeptidase with thrombospondin type 1 motif 2 inactivation reduces the extent and stability of carbon tetrachloride-induced hepatic fibrosis in mice
-
Kesteloot F, Desmouliere A, Leclercq I, et al. ADAM metallopeptidase with thrombospondin type 1 motif 2 inactivation reduces the extent and stability of carbon tetrachloride-induced hepatic fibrosis in mice. Hepatology 2007, 46(5):1620-1631.
-
(2007)
Hepatology
, vol.46
, Issue.5
, pp. 1620-1631
-
-
Kesteloot, F.1
Desmouliere, A.2
Leclercq, I.3
-
26
-
-
84878060967
-
Increased ADAMTS-13 proteolytic activity in rat hepatic stellate cells upon activation in vitro and in vivo
-
Niiya M, Uemura M, Zheng XW, et al. Increased ADAMTS-13 proteolytic activity in rat hepatic stellate cells upon activation in vitro and in vivo. J Thromb Haemost 2006, 4(5):1063-1070.
-
(2006)
J Thromb Haemost
, vol.4
, Issue.5
, pp. 1063-1070
-
-
Niiya, M.1
Uemura, M.2
Zheng, X.W.3
-
27
-
-
84894064870
-
A disintegrin and metalloproteinase 17 (ADAM17) mediates epidermal growth factor receptor transactivation by angiotensin II on hepatic stellate cells
-
Oikawa H, Maesawa C, Tatemichi Y, et al. A disintegrin and metalloproteinase 17 (ADAM17) mediates epidermal growth factor receptor transactivation by angiotensin II on hepatic stellate cells. Life Sci 2014, 97(2):137-144.
-
(2014)
Life Sci
, vol.97
, Issue.2
, pp. 137-144
-
-
Oikawa, H.1
Maesawa, C.2
Tatemichi, Y.3
-
28
-
-
15444379753
-
The role of matrix stiffness in hepatic stellate cell activation and liver fibrosis
-
Wells RG The role of matrix stiffness in hepatic stellate cell activation and liver fibrosis. J Clin Gastroenterol 2005, 39(4 Suppl. 2):S158-S161.
-
(2005)
J Clin Gastroenterol
, vol.39
, Issue.4
, pp. S158-S161
-
-
Wells, R.G.1
-
29
-
-
37149050014
-
Increased stiffness of the rat liver precedes matrix deposition: implications for fibrosis
-
Georges PC, Hui JJ, Gombos Z, et al. Increased stiffness of the rat liver precedes matrix deposition: implications for fibrosis. Am J Physiol Gastrointest Liver Physiol 2007, 293(6):G1147-G1154.
-
(2007)
Am J Physiol Gastrointest Liver Physiol
, vol.293
, Issue.6
, pp. G1147-G1154
-
-
Georges, P.C.1
Hui, J.J.2
Gombos, Z.3
-
30
-
-
33847363203
-
Models of liver fibrosis: exploring the dynamic nature of inflammation and repair in a solid organ
-
Iredale JP Models of liver fibrosis: exploring the dynamic nature of inflammation and repair in a solid organ. J Clin Invest 2007, 117(3):539-548.
-
(2007)
J Clin Invest
, vol.117
, Issue.3
, pp. 539-548
-
-
Iredale, J.P.1
-
32
-
-
0036139102
-
Stimulation and proliferation of primary rat hepatic stellate cells by cytochrome P450 2E1-derived reactive oxygen species
-
Nieto N, Friedman SL, Cederbaum AI Stimulation and proliferation of primary rat hepatic stellate cells by cytochrome P450 2E1-derived reactive oxygen species. Hepatology 2002, 35(1):62-73.
-
(2002)
Hepatology
, vol.35
, Issue.1
, pp. 62-73
-
-
Nieto, N.1
Friedman, S.L.2
Cederbaum, A.I.3
-
33
-
-
0037155835
-
Cytochrome P450 2E1-derived reactive oxygen species mediate paracrine stimulation of collagen I protein synthesis by hepatic stellate cells
-
Nieto N, Friedman SL, Cederbaum AI Cytochrome P450 2E1-derived reactive oxygen species mediate paracrine stimulation of collagen I protein synthesis by hepatic stellate cells. J Biol Chem 2002, 277(12):9853-9864.
-
(2002)
J Biol Chem
, vol.277
, Issue.12
, pp. 9853-9864
-
-
Nieto, N.1
Friedman, S.L.2
Cederbaum, A.I.3
-
34
-
-
0034092716
-
CYP2E1 and CYP4A as microsomal catalysts of lipid peroxides in murine nonalcoholic steatohepatitis
-
Leclercq IA, Farrell GC, Field J, et al. CYP2E1 and CYP4A as microsomal catalysts of lipid peroxides in murine nonalcoholic steatohepatitis. J Clin Invest 2000, 105(8):1067-1075.
-
(2000)
J Clin Invest
, vol.105
, Issue.8
, pp. 1067-1075
-
-
Leclercq, I.A.1
Farrell, G.C.2
Field, J.3
-
35
-
-
0036788277
-
Fas enhances fibrogenesis in the bile duct ligated mouse: a link between apoptosis and fibrosis
-
Canbay A, Higuchi H, Bronk SF, et al. Fas enhances fibrogenesis in the bile duct ligated mouse: a link between apoptosis and fibrosis. Gastroenterology 2002, 123(4):1323-1330.
-
(2002)
Gastroenterology
, vol.123
, Issue.4
, pp. 1323-1330
-
-
Canbay, A.1
Higuchi, H.2
Bronk, S.F.3
-
36
-
-
0038476330
-
Apoptotic body engulfment by a human stellate cell line is profibrogenic
-
Canbay A, Taimr P, Torok N, et al. Apoptotic body engulfment by a human stellate cell line is profibrogenic. Lab Invest 2003, 83(5):655-663.
-
(2003)
Lab Invest
, vol.83
, Issue.5
, pp. 655-663
-
-
Canbay, A.1
Taimr, P.2
Torok, N.3
-
37
-
-
84862604750
-
Autophagy fuels tissue fibrogenesis
-
Hernandez-Gea V, Friedman SL Autophagy fuels tissue fibrogenesis. Autophagy 2012, 8(5):849-850.
-
(2012)
Autophagy
, vol.8
, Issue.5
, pp. 849-850
-
-
Hernandez-Gea, V.1
Friedman, S.L.2
-
38
-
-
84859444880
-
Autophagy releases lipid that promotes fibrogenesis by activated hepatic stellate cells in mice and in human tissues
-
Hernandez-Gea V, Ghiassi-Nejad Z, Rozenfeld R, et al. Autophagy releases lipid that promotes fibrogenesis by activated hepatic stellate cells in mice and in human tissues. Gastroenterology 2012, 142(4):938-946.
-
(2012)
Gastroenterology
, vol.142
, Issue.4
, pp. 938-946
-
-
Hernandez-Gea, V.1
Ghiassi-Nejad, Z.2
Rozenfeld, R.3
-
39
-
-
84879160597
-
Endoplasmic reticulum stress induces fibrogenic activity in hepatic stellate cells through autophagy
-
Hernandez-Gea V, Hilscher M, Rozenfeld R, et al. Endoplasmic reticulum stress induces fibrogenic activity in hepatic stellate cells through autophagy. J Hepatol 2013, 59(1):98-104.
-
(2013)
J Hepatol
, vol.59
, Issue.1
, pp. 98-104
-
-
Hernandez-Gea, V.1
Hilscher, M.2
Rozenfeld, R.3
-
40
-
-
51349168307
-
Sinusoidal endothelial cells prevent rat stellate cell activation and promote reversion to quiescence
-
Deleve LD, Wang X, Guo Y Sinusoidal endothelial cells prevent rat stellate cell activation and promote reversion to quiescence. Hepatology 2008, 48(3):920-930.
-
(2008)
Hepatology
, vol.48
, Issue.3
, pp. 920-930
-
-
Deleve, L.D.1
Wang, X.2
Guo, Y.3
-
41
-
-
84859392954
-
Role of differentiation of liver sinusoidal endothelial cells in progression and regression of hepatic fibrosis in rats
-
e916
-
Xie G, Wang X, Wang L, et al. Role of differentiation of liver sinusoidal endothelial cells in progression and regression of hepatic fibrosis in rats. Gastroenterology 2012, 142(4):918-927. e916.
-
(2012)
Gastroenterology
, vol.142
, Issue.4
, pp. 918-927
-
-
Xie, G.1
Wang, X.2
Wang, L.3
-
42
-
-
79960109597
-
A transgenic model for conditional induction and rescue of portal hypertension reveals a role of VEGF-mediated regulation of sinusoidal fenestrations
-
May D, Djonov V, Zamir G, et al. A transgenic model for conditional induction and rescue of portal hypertension reveals a role of VEGF-mediated regulation of sinusoidal fenestrations. PLoS One 2011, 6(7):e21478.
-
(2011)
PLoS One
, vol.6
, Issue.7
, pp. e21478
-
-
May, D.1
Djonov, V.2
Zamir, G.3
-
43
-
-
84913580343
-
Extra-hepatic PDGFB, delivered by platelets, promotes activation of hepatic stellate cells and biliary fibrosis in mice
-
Yoshida S, Ikenaga N, Liu SB, et al. Extra-hepatic PDGFB, delivered by platelets, promotes activation of hepatic stellate cells and biliary fibrosis in mice. Gastroenterology 2014, http://dx.doi.org/10.1053/j.gastro.2014.08.038.
-
(2014)
Gastroenterology
-
-
Yoshida, S.1
Ikenaga, N.2
Liu, S.B.3
-
44
-
-
84055199659
-
Platelet-derived adenosine 5'-triphosphate suppresses activation of human hepatic stellate cell: in vitro study
-
Ikeda N, Murata S, Maruyama T, et al. Platelet-derived adenosine 5'-triphosphate suppresses activation of human hepatic stellate cell: in vitro study. Hepatol Res 2012, 42(1):91-102.
-
(2012)
Hepatol Res
, vol.42
, Issue.1
, pp. 91-102
-
-
Ikeda, N.1
Murata, S.2
Maruyama, T.3
-
45
-
-
77955950139
-
Expression of platelet-derived growth factor (PDGF)-B and PDGF-receptor beta is associated with lymphatic metastasis in human gastric carcinoma
-
Kodama M, Kitadai Y, Sumida T, et al. Expression of platelet-derived growth factor (PDGF)-B and PDGF-receptor beta is associated with lymphatic metastasis in human gastric carcinoma. Cancer Sci 2010, 101(9):1984-1989.
-
(2010)
Cancer Sci
, vol.101
, Issue.9
, pp. 1984-1989
-
-
Kodama, M.1
Kitadai, Y.2
Sumida, T.3
-
46
-
-
0025132840
-
Transport and storage of vitamin A
-
Blomhoff R, Green MH, Berg T, Norum KR Transport and storage of vitamin A. Science 1990, 250(4979):399-404.
-
(1990)
Science
, vol.250
, Issue.4979
, pp. 399-404
-
-
Blomhoff, R.1
Green, M.H.2
Berg, T.3
Norum, K.R.4
-
47
-
-
84879000583
-
Retinol and retinyl esters: biochemistry and physiology
-
O'Byrne SM, Blaner WS Retinol and retinyl esters: biochemistry and physiology. J Lipid Res 2013, 54(7):1731-1743.
-
(2013)
J Lipid Res
, vol.54
, Issue.7
, pp. 1731-1743
-
-
O'Byrne, S.M.1
Blaner, W.S.2
-
48
-
-
27444438178
-
Retinoid absorption and storage is impaired in mice lacking lecithin:retinol acyltransferase (LRAT)
-
O'Byrne SM, Wongsiriroj N, Libien J, et al. Retinoid absorption and storage is impaired in mice lacking lecithin:retinol acyltransferase (LRAT). J Biol Chem 2005, 280(42):35647-35657.
-
(2005)
J Biol Chem
, vol.280
, Issue.42
, pp. 35647-35657
-
-
O'Byrne, S.M.1
Wongsiriroj, N.2
Libien, J.3
-
49
-
-
0025688897
-
Retinoic acid modulates rat Ito cell proliferation, collagen, and transforming growth factor beta production
-
Davis BH, Kramer RT, Davidson NO Retinoic acid modulates rat Ito cell proliferation, collagen, and transforming growth factor beta production. J Clin Invest 1990, 86(6):2062-2070.
-
(1990)
J Clin Invest
, vol.86
, Issue.6
, pp. 2062-2070
-
-
Davis, B.H.1
Kramer, R.T.2
Davidson, N.O.3
-
50
-
-
0025811045
-
Liver damage caused by therapeutic vitamin A administration: estimate of dose-related toxicity in 41 cases
-
Geubel AP, De Galocsy C, Alves N, Rahier J, Dive C Liver damage caused by therapeutic vitamin A administration: estimate of dose-related toxicity in 41 cases. Gastroenterology 1991, 100(6):1701-1709.
-
(1991)
Gastroenterology
, vol.100
, Issue.6
, pp. 1701-1709
-
-
Geubel, A.P.1
De Galocsy, C.2
Alves, N.3
Rahier, J.4
Dive, C.5
-
51
-
-
1442282022
-
Differential modulation of rat hepatic stellate phenotype by natural and synthetic retinoids
-
Hellemans K, Verbuyst P, Quartier E, et al. Differential modulation of rat hepatic stellate phenotype by natural and synthetic retinoids. Hepatology 2004, 39(1):97-108.
-
(2004)
Hepatology
, vol.39
, Issue.1
, pp. 97-108
-
-
Hellemans, K.1
Verbuyst, P.2
Quartier, E.3
-
52
-
-
0030755313
-
Retinoids exacerbate rat liver fibrosis by inducing the activation of latent TGF-beta in liver stellate cells
-
Okuno M, Moriwaki H, Imai S, et al. Retinoids exacerbate rat liver fibrosis by inducing the activation of latent TGF-beta in liver stellate cells. Hepatology 1997, 26(4):913-921.
-
(1997)
Hepatology
, vol.26
, Issue.4
, pp. 913-921
-
-
Okuno, M.1
Moriwaki, H.2
Imai, S.3
-
53
-
-
0021963808
-
Suppression of experimental hepatic fibrosis by administration of vitamin A
-
Senoo H, Wake K Suppression of experimental hepatic fibrosis by administration of vitamin A. Lab Invest 1985, 52(2):182-194.
-
(1985)
Lab Invest
, vol.52
, Issue.2
, pp. 182-194
-
-
Senoo, H.1
Wake, K.2
-
54
-
-
80051551271
-
Absence of hepatic stellate cell retinoid lipid droplets does not enhance hepatic fibrosis but decreases hepatic carcinogenesis
-
Kluwe J, Wongsiriroj N, Troeger JS, et al. Absence of hepatic stellate cell retinoid lipid droplets does not enhance hepatic fibrosis but decreases hepatic carcinogenesis. Gut 2011, 60(9):1260-1268.
-
(2011)
Gut
, vol.60
, Issue.9
, pp. 1260-1268
-
-
Kluwe, J.1
Wongsiriroj, N.2
Troeger, J.S.3
-
55
-
-
33846951514
-
Emerging insights into transforming growth factor beta Smad signal in hepatic fibrogenesis
-
Inagaki Y, Okazaki I Emerging insights into transforming growth factor beta Smad signal in hepatic fibrogenesis. Gut 2007, 56(2):284-292.
-
(2007)
Gut
, vol.56
, Issue.2
, pp. 284-292
-
-
Inagaki, Y.1
Okazaki, I.2
-
56
-
-
31944433741
-
TGF-beta/Smad signaling in the injured liver
-
Breitkopf K, Godoy P, Ciuclan L, Singer MV, Dooley S TGF-beta/Smad signaling in the injured liver. Z Gastroenterol 2006, 44(1):57-66.
-
(2006)
Z Gastroenterol
, vol.44
, Issue.1
, pp. 57-66
-
-
Breitkopf, K.1
Godoy, P.2
Ciuclan, L.3
Singer, M.V.4
Dooley, S.5
-
57
-
-
1642524221
-
Peroxisome proliferator-activated receptor gamma induces a phenotypic switch from activated to quiescent hepatic stellate cells
-
Hazra S, Xiong S, Wang J, et al. Peroxisome proliferator-activated receptor gamma induces a phenotypic switch from activated to quiescent hepatic stellate cells. J Biol Chem 2004, 279(12):11392-11401.
-
(2004)
J Biol Chem
, vol.279
, Issue.12
, pp. 11392-11401
-
-
Hazra, S.1
Xiong, S.2
Wang, J.3
-
58
-
-
42549114387
-
Activation of peroxisome proliferator-activated receptor-gamma by curcumin blocks the signaling pathways for PDGF and EGF in hepatic stellate cells
-
Lin J, Chen A Activation of peroxisome proliferator-activated receptor-gamma by curcumin blocks the signaling pathways for PDGF and EGF in hepatic stellate cells. Lab Invest 2008, 88(5):529-540.
-
(2008)
Lab Invest
, vol.88
, Issue.5
, pp. 529-540
-
-
Lin, J.1
Chen, A.2
-
59
-
-
84902663562
-
Osteopontin induces ductular reaction contributing to liver fibrosis
-
Wang X, Lopategi A, Ge X, et al. Osteopontin induces ductular reaction contributing to liver fibrosis. Gut 2014, http://dx.doi.org/10.1136/gutjnl-2013-306373.
-
(2014)
Gut
-
-
Wang, X.1
Lopategi, A.2
Ge, X.3
-
60
-
-
84896754721
-
Transcriptional repression of the transforming growth factor beta (TGF-beta) Pseudoreceptor BMP and activin membrane-bound inhibitor (BAMBI) by Nuclear Factor kappaB (NF-kappaB) p50 enhances TGF-beta signaling in hepatic stellate cells
-
Liu C, Chen X, Yang L, et al. Transcriptional repression of the transforming growth factor beta (TGF-beta) Pseudoreceptor BMP and activin membrane-bound inhibitor (BAMBI) by Nuclear Factor kappaB (NF-kappaB) p50 enhances TGF-beta signaling in hepatic stellate cells. J Biol Chem 2014, 289(10):7082-7091.
-
(2014)
J Biol Chem
, vol.289
, Issue.10
, pp. 7082-7091
-
-
Liu, C.1
Chen, X.2
Yang, L.3
-
61
-
-
84907485547
-
IL-17A enhances the expression of profibrotic genes through upregulation of the TGF-beta receptor on hepatic stellate cells in a JNK-dependent manner
-
Fabre T, Kared H, Friedman SL, Shoukry NH IL-17A enhances the expression of profibrotic genes through upregulation of the TGF-beta receptor on hepatic stellate cells in a JNK-dependent manner. J Immunol 2014, http://dx.doi.org/10.4049/jimmunol.1400861.
-
(2014)
J Immunol
-
-
Fabre, T.1
Kared, H.2
Friedman, S.L.3
Shoukry, N.H.4
-
62
-
-
84907519671
-
PDGF receptor alpha promotes TGF-beta signaling in hepatic stellate cells via transcriptional and post transcriptional regulation of TGF-beta receptors
-
Liu C, Li J, Xiang X, et al. PDGF receptor alpha promotes TGF-beta signaling in hepatic stellate cells via transcriptional and post transcriptional regulation of TGF-beta receptors. Am J Physiol Gastrointest Liver Physiol 2014, http://dx.doi.org/10.1152/ajpgi.00138.2014.
-
(2014)
Am J Physiol Gastrointest Liver Physiol
-
-
Liu, C.1
Li, J.2
Xiang, X.3
-
63
-
-
84928883882
-
Vitamin D counteracts fibrogenic TGF-beta signalling in human hepatic stellate cells both receptor-dependently and independently
-
Beilfuss A, Sowa JP, Sydor S, et al. Vitamin D counteracts fibrogenic TGF-beta signalling in human hepatic stellate cells both receptor-dependently and independently. Gut 2014, http://dx.doi.org/10.1136/gutjnl-2014-307024.
-
(2014)
Gut
-
-
Beilfuss, A.1
Sowa, J.P.2
Sydor, S.3
-
64
-
-
84860349542
-
Regulation of hepatic stellate cells by connective tissue growth factor
-
Huang G, Brigstock DR Regulation of hepatic stellate cells by connective tissue growth factor. Front Biosci (Landmark Ed) 2012, 17:2495-2507.
-
(2012)
Front Biosci (Landmark Ed)
, vol.17
, pp. 2495-2507
-
-
Huang, G.1
Brigstock, D.R.2
-
65
-
-
1542305557
-
Connective tissue growth factor (CCN2) induces adhesion of rat activated hepatic stellate cells by binding of its C-terminal domain to integrin alpha(v)beta(3) and heparan sulfate proteoglycan
-
Gao R, Brigstock DR Connective tissue growth factor (CCN2) induces adhesion of rat activated hepatic stellate cells by binding of its C-terminal domain to integrin alpha(v)beta(3) and heparan sulfate proteoglycan. J Biol Chem 2004, 279(10):8848-8855.
-
(2004)
J Biol Chem
, vol.279
, Issue.10
, pp. 8848-8855
-
-
Gao, R.1
Brigstock, D.R.2
-
66
-
-
84863042103
-
Osteopontin, an oxidant stress sensitive cytokine, up-regulates collagen-I via integrin alpha(V)beta(3) engagement and PI3K/pAkt/NFkappaB signaling
-
Urtasun R, Lopategi A, George J, et al. Osteopontin, an oxidant stress sensitive cytokine, up-regulates collagen-I via integrin alpha(V)beta(3) engagement and PI3K/pAkt/NFkappaB signaling. Hepatology 2012, 55(2):594-608.
-
(2012)
Hepatology
, vol.55
, Issue.2
, pp. 594-608
-
-
Urtasun, R.1
Lopategi, A.2
George, J.3
-
67
-
-
84884889335
-
Osteopontin delays resolution of liver fibrosis
-
Leung TM, Wang X, Kitamura N, Fiel MI, Nieto N Osteopontin delays resolution of liver fibrosis. Lab Invest 2013, 93(10):1082-1089.
-
(2013)
Lab Invest
, vol.93
, Issue.10
, pp. 1082-1089
-
-
Leung, T.M.1
Wang, X.2
Kitamura, N.3
Fiel, M.I.4
Nieto, N.5
-
69
-
-
84859509946
-
Autophagy promotes intracellular degradation of type I collagen induced by transforming growth factor (TGF)-beta1
-
Kim SI, Na HJ, Ding Y, et al. Autophagy promotes intracellular degradation of type I collagen induced by transforming growth factor (TGF)-beta1. J Biol Chem 2012, 287(15):11677-11688.
-
(2012)
J Biol Chem
, vol.287
, Issue.15
, pp. 11677-11688
-
-
Kim, S.I.1
Na, H.J.2
Ding, Y.3
-
70
-
-
66349112572
-
Autophagic elimination of misfolded procollagen aggregates in the endoplasmic reticulum as a means of cell protection
-
Ishida Y, Yamamoto A, Kitamura A, et al. Autophagic elimination of misfolded procollagen aggregates in the endoplasmic reticulum as a means of cell protection. Mol Biol Cell 2009, 20(11):2744-2754.
-
(2009)
Mol Biol Cell
, vol.20
, Issue.11
, pp. 2744-2754
-
-
Ishida, Y.1
Yamamoto, A.2
Kitamura, A.3
-
71
-
-
34250346521
-
Hepatic stellate cell protrusions couple platelet-derived growth factor-BB to chemotaxis
-
Melton AC, Yee HF Hepatic stellate cell protrusions couple platelet-derived growth factor-BB to chemotaxis. Hepatology 2007, 45(6):1446-1453.
-
(2007)
Hepatology
, vol.45
, Issue.6
, pp. 1446-1453
-
-
Melton, A.C.1
Yee, H.F.2
-
72
-
-
34447317835
-
Proangiogenic cytokines as hypoxia-dependent factors stimulating migration of human hepatic stellate cells
-
Novo E, Cannito S, Zamara E, et al. Proangiogenic cytokines as hypoxia-dependent factors stimulating migration of human hepatic stellate cells. Am J Pathol 2007, 170(6):1942-1953.
-
(2007)
Am J Pathol
, vol.170
, Issue.6
, pp. 1942-1953
-
-
Novo, E.1
Cannito, S.2
Zamara, E.3
-
73
-
-
0037221910
-
Liver fibrosis: insights into migration of hepatic stellate cells in response to extracellular matrix and growth factors
-
Yang C, Zeisberg M, Mosterman B, et al. Liver fibrosis: insights into migration of hepatic stellate cells in response to extracellular matrix and growth factors. Gastroenterology 2003, 124(1):147-159.
-
(2003)
Gastroenterology
, vol.124
, Issue.1
, pp. 147-159
-
-
Yang, C.1
Zeisberg, M.2
Mosterman, B.3
-
74
-
-
0032934278
-
Monocyte chemotactic protein-1 as a chemoattractant for human hepatic stellate cells
-
Marra F, Romanelli RG, Giannini C, et al. Monocyte chemotactic protein-1 as a chemoattractant for human hepatic stellate cells. Hepatology 1999, 29(1):140-148.
-
(1999)
Hepatology
, vol.29
, Issue.1
, pp. 140-148
-
-
Marra, F.1
Romanelli, R.G.2
Giannini, C.3
-
75
-
-
79954558900
-
Intracellular reactive oxygen species are required for directional migration of resident and bone marrow-derived hepatic pro-fibrogenic cells
-
Novo E, Busletta C, Bonzo LV, et al. Intracellular reactive oxygen species are required for directional migration of resident and bone marrow-derived hepatic pro-fibrogenic cells. J Hepatol 2011, 54(5):964-974.
-
(2011)
J Hepatol
, vol.54
, Issue.5
, pp. 964-974
-
-
Novo, E.1
Busletta, C.2
Bonzo, L.V.3
-
76
-
-
79955091590
-
The nicotinamide adenine dinucleotide phosphate oxidase (NOX) homologues NOX1 and NOX2/gp91(phox) mediate hepatic fibrosis in mice
-
Paik YH, Iwaisako K, Seki E, et al. The nicotinamide adenine dinucleotide phosphate oxidase (NOX) homologues NOX1 and NOX2/gp91(phox) mediate hepatic fibrosis in mice. Hepatology 2011, 53(5):1730-1741.
-
(2011)
Hepatology
, vol.53
, Issue.5
, pp. 1730-1741
-
-
Paik, Y.H.1
Iwaisako, K.2
Seki, E.3
-
77
-
-
84856751507
-
The biphasic nature of hypoxia-induced directional migration of activated human hepatic stellate cells
-
Novo E, Povero D, Busletta C, et al. The biphasic nature of hypoxia-induced directional migration of activated human hepatic stellate cells. J Pathol 2012, 226(4):588-597.
-
(2012)
J Pathol
, vol.226
, Issue.4
, pp. 588-597
-
-
Novo, E.1
Povero, D.2
Busletta, C.3
-
79
-
-
0028170153
-
Induction of beta-platelet-derived growth factor receptor in rat hepatic lipocytes during cellular activation in vivo and in culture
-
Wong L, Yamasaki G, Johnson RJ, Friedman SL Induction of beta-platelet-derived growth factor receptor in rat hepatic lipocytes during cellular activation in vivo and in culture. J Clin Invest 1994, 94(4):1563-1569.
-
(1994)
J Clin Invest
, vol.94
, Issue.4
, pp. 1563-1569
-
-
Wong, L.1
Yamasaki, G.2
Johnson, R.J.3
Friedman, S.L.4
-
80
-
-
0025776396
-
Platelet-derived growth factor (PDGF) stimulates PDGF receptor subunit dimerization and intersubunit trans-phosphorylation
-
Kelly JD, Haldeman BA, Grant FJ, et al. Platelet-derived growth factor (PDGF) stimulates PDGF receptor subunit dimerization and intersubunit trans-phosphorylation. J Biol Chem 1991, 266(14):8987-8992.
-
(1991)
J Biol Chem
, vol.266
, Issue.14
, pp. 8987-8992
-
-
Kelly, J.D.1
Haldeman, B.A.2
Grant, F.J.3
-
81
-
-
0028855914
-
The mitogenic effect of platelet-derived growth factor in human hepatic stellate cells requires calcium influx
-
Failli P, Ruocco C, De Franco R, et al. The mitogenic effect of platelet-derived growth factor in human hepatic stellate cells requires calcium influx. Am J Physiol 1995, 269(5 Pt 1):C1133-C1139.
-
(1995)
Am J Physiol
, vol.269
, Issue.5
, pp. C1133-C1139
-
-
Failli, P.1
Ruocco, C.2
De Franco, R.3
-
82
-
-
79959547264
-
Critical role of tumor necrosis factor receptor 1, but not 2, in hepatic stellate cell proliferation, extracellular matrix remodeling, and liver fibrogenesis
-
Tarrats N, Moles A, Morales A, et al. Critical role of tumor necrosis factor receptor 1, but not 2, in hepatic stellate cell proliferation, extracellular matrix remodeling, and liver fibrogenesis. Hepatology 2011, 54(1):319-327.
-
(2011)
Hepatology
, vol.54
, Issue.1
, pp. 319-327
-
-
Tarrats, N.1
Moles, A.2
Morales, A.3
-
83
-
-
33947414087
-
Sinusoidal remodeling and angiogenesis: a new function for the liver-specific pericyte?
-
Lee JS, Semela D, Iredale J, Shah VH Sinusoidal remodeling and angiogenesis: a new function for the liver-specific pericyte?. Hepatology 2007, 45(3):817-825.
-
(2007)
Hepatology
, vol.45
, Issue.3
, pp. 817-825
-
-
Lee, J.S.1
Semela, D.2
Iredale, J.3
Shah, V.H.4
-
84
-
-
84869203453
-
Increased number and function of endothelial progenitor cells stimulate angiogenesis by resident liver sinusoidal endothelial cells (SECs) in cirrhosis through paracrine factors
-
Kaur S, Tripathi D, Dongre K, et al. Increased number and function of endothelial progenitor cells stimulate angiogenesis by resident liver sinusoidal endothelial cells (SECs) in cirrhosis through paracrine factors. J Hepatol 2012, 57(6):1193-1198.
-
(2012)
J Hepatol
, vol.57
, Issue.6
, pp. 1193-1198
-
-
Kaur, S.1
Tripathi, D.2
Dongre, K.3
-
85
-
-
0033608164
-
Expressions of vascular endothelial growth factor in nonparenchymal as well as parenchymal cells in rat liver after necrosis
-
Ishikawa K, Mochida S, Mashiba S, et al. Expressions of vascular endothelial growth factor in nonparenchymal as well as parenchymal cells in rat liver after necrosis. Biochem Biophys Res Commun 1999, 254(3):587-593.
-
(1999)
Biochem Biophys Res Commun
, vol.254
, Issue.3
, pp. 587-593
-
-
Ishikawa, K.1
Mochida, S.2
Mashiba, S.3
-
86
-
-
84860396699
-
Hepatic stellate cells produce vascular endothelial growth factor via phospho-p44/42 mitogen-activated protein kinase/cyclooxygenase-2 pathway
-
Zhao Y, Wang Y, Wang Q, et al. Hepatic stellate cells produce vascular endothelial growth factor via phospho-p44/42 mitogen-activated protein kinase/cyclooxygenase-2 pathway. Mol Cell Biochem 2012, 359(1-2):217-223.
-
(2012)
Mol Cell Biochem
, vol.359
, Issue.1-2
, pp. 217-223
-
-
Zhao, Y.1
Wang, Y.2
Wang, Q.3
-
87
-
-
0042887507
-
Vascular endothelial growth factor and receptor interaction is a prerequisite for murine hepatic fibrogenesis
-
Yoshiji H, Kuriyama S, Yoshii J, et al. Vascular endothelial growth factor and receptor interaction is a prerequisite for murine hepatic fibrogenesis. Gut 2003, 52(9):1347-1354.
-
(2003)
Gut
, vol.52
, Issue.9
, pp. 1347-1354
-
-
Yoshiji, H.1
Kuriyama, S.2
Yoshii, J.3
-
88
-
-
84880282256
-
Marked 25-hydroxyvitamin D deficiency is associated with poor prognosis in patients with alcoholic liver disease
-
Trepo E, Ouziel R, Pradat P, et al. Marked 25-hydroxyvitamin D deficiency is associated with poor prognosis in patients with alcoholic liver disease. J Hepatol 2013, 59(2):344-350.
-
(2013)
J Hepatol
, vol.59
, Issue.2
, pp. 344-350
-
-
Trepo, E.1
Ouziel, R.2
Pradat, P.3
-
89
-
-
84927724482
-
Prediagnostic circulating vitamin D levels and risk of hepatocellular carcinoma in European populations: a nested case-control study
-
Fedirko V, Duarte-Salles T, Bamia C, et al. Prediagnostic circulating vitamin D levels and risk of hepatocellular carcinoma in European populations: a nested case-control study. Hepatology 2014, http://dx.doi.org/10.1002/hep.27079.
-
(2014)
Hepatology
-
-
Fedirko, V.1
Duarte-Salles, T.2
Bamia, C.3
-
90
-
-
80655127773
-
Vitamin D inhibits proliferation and profibrotic marker expression in hepatic stellate cells and decreases thioacetamide-induced liver fibrosis in rats
-
Abramovitch S, Dahan-Bachar L, Sharvit E, et al. Vitamin D inhibits proliferation and profibrotic marker expression in hepatic stellate cells and decreases thioacetamide-induced liver fibrosis in rats. Gut 2011, 60(12):1728-1737.
-
(2011)
Gut
, vol.60
, Issue.12
, pp. 1728-1737
-
-
Abramovitch, S.1
Dahan-Bachar, L.2
Sharvit, E.3
-
91
-
-
84876928036
-
A vitamin D receptor/SMAD genomic circuit gates hepatic fibrotic response
-
Ding N, Yu RT, Subramaniam N, et al. A vitamin D receptor/SMAD genomic circuit gates hepatic fibrotic response. Cell 2013, 153(3):601-613.
-
(2013)
Cell
, vol.153
, Issue.3
, pp. 601-613
-
-
Ding, N.1
Yu, R.T.2
Subramaniam, N.3
-
92
-
-
79957943503
-
Increased contractility of hepatic stellate cells in cirrhosis is mediated by enhanced Ca2+-dependent and Ca2+-sensitization pathways
-
Iizuka M, Murata T, Hori M, Ozaki H Increased contractility of hepatic stellate cells in cirrhosis is mediated by enhanced Ca2+-dependent and Ca2+-sensitization pathways. Am J Physiol Gastrointest Liver Physiol 2011, 300(6):G1010-G1021.
-
(2011)
Am J Physiol Gastrointest Liver Physiol
, vol.300
, Issue.6
, pp. G1010-G1021
-
-
Iizuka, M.1
Murata, T.2
Hori, M.3
Ozaki, H.4
-
93
-
-
84883334111
-
CXCL12 induces hepatic stellate cell contraction through a calcium-independent pathway
-
Saiman Y, Agarwal R, Hickman DA, et al. CXCL12 induces hepatic stellate cell contraction through a calcium-independent pathway. Am J Physiol Gastrointest Liver Physiol 2013, 305(5):G375-G382.
-
(2013)
Am J Physiol Gastrointest Liver Physiol
, vol.305
, Issue.5
, pp. G375-G382
-
-
Saiman, Y.1
Agarwal, R.2
Hickman, D.A.3
-
94
-
-
33644807897
-
[Ca2+]i-independent contractile force generation by rat hepatic stellate cells in response to endothelin-1
-
Melton AC, Datta A, Yee HF [Ca2+]i-independent contractile force generation by rat hepatic stellate cells in response to endothelin-1. Am J Physiol Gastrointest Liver Physiol 2006, 290(1):G7-G13.
-
(2006)
Am J Physiol Gastrointest Liver Physiol
, vol.290
, Issue.1
, pp. G7-G13
-
-
Melton, A.C.1
Datta, A.2
Yee, H.F.3
-
95
-
-
0032775098
-
Quantitation of rat hepatic stellate cell contraction: stellate cells' contribution to sinusoidal resistance
-
Thimgan MS, Yee HF Quantitation of rat hepatic stellate cell contraction: stellate cells' contribution to sinusoidal resistance. Am J Physiol 1999, 277(1 Pt 1):G137-G143.
-
(1999)
Am J Physiol
, vol.277
, Issue.1
, pp. G137-G143
-
-
Thimgan, M.S.1
Yee, H.F.2
-
96
-
-
0033613951
-
Regulation of endothelin-1 synthesis by endothelin-converting enzyme-1 during wound healing
-
Shao R, Yan W, Rockey DC Regulation of endothelin-1 synthesis by endothelin-converting enzyme-1 during wound healing. J Biol Chem 1999, 274(5):3228-3234.
-
(1999)
J Biol Chem
, vol.274
, Issue.5
, pp. 3228-3234
-
-
Shao, R.1
Yan, W.2
Rockey, D.C.3
-
97
-
-
0027496798
-
Endothelin receptors in rat liver: lipocytes as a contractile target for endothelin 1
-
Housset C, Rockey DC, Bissell DM Endothelin receptors in rat liver: lipocytes as a contractile target for endothelin 1. Proc Natl Acad Sci USA 1993, 90(20):9266-9270.
-
(1993)
Proc Natl Acad Sci USA
, vol.90
, Issue.20
, pp. 9266-9270
-
-
Housset, C.1
Rockey, D.C.2
Bissell, D.M.3
-
98
-
-
0345118191
-
Deficit in nitric oxide production in cirrhotic rat livers is located in the sinusoidal and postsinusoidal areas
-
Loureiro-Silva MR, Cadelina GW, Groszmann RJ Deficit in nitric oxide production in cirrhotic rat livers is located in the sinusoidal and postsinusoidal areas. Am J Physiol Gastrointest Liver Physiol 2003, 284(4):G567-G574.
-
(2003)
Am J Physiol Gastrointest Liver Physiol
, vol.284
, Issue.4
, pp. G567-G574
-
-
Loureiro-Silva, M.R.1
Cadelina, G.W.2
Groszmann, R.J.3
-
99
-
-
84896493187
-
Relaxin modulates human and rat hepatic myofibroblast function and ameliorates portal hypertension in vivo
-
Fallowfield JA, Hayden AL, Snowdon VK, et al. Relaxin modulates human and rat hepatic myofibroblast function and ameliorates portal hypertension in vivo. Hepatology 2014, 59(4):1492-1504.
-
(2014)
Hepatology
, vol.59
, Issue.4
, pp. 1492-1504
-
-
Fallowfield, J.A.1
Hayden, A.L.2
Snowdon, V.K.3
-
100
-
-
84858068082
-
Hepatitis B-associated fibrosis and fibrosis/cirrhosis regression with nucleoside and nucleotide analogs
-
Brown A, Goodman Z Hepatitis B-associated fibrosis and fibrosis/cirrhosis regression with nucleoside and nucleotide analogs. Expert Rev Gastroenterol Hepatol 2012, 6(2):187-198.
-
(2012)
Expert Rev Gastroenterol Hepatol
, vol.6
, Issue.2
, pp. 187-198
-
-
Brown, A.1
Goodman, Z.2
-
101
-
-
84867119109
-
Liver fibrosis: a bidirectional model of fibrogenesis and resolution
-
Ramachandran P, Iredale JP Liver fibrosis: a bidirectional model of fibrogenesis and resolution. QJM 2012, 105(9):813-817.
-
(2012)
QJM
, vol.105
, Issue.9
, pp. 813-817
-
-
Ramachandran, P.1
Iredale, J.P.2
-
102
-
-
84859590655
-
Clinical evidence for the regression of liver fibrosis
-
Ellis EL, Mann DA Clinical evidence for the regression of liver fibrosis. J Hepatol 2012, 56(5):1171-1180.
-
(2012)
J Hepatol
, vol.56
, Issue.5
, pp. 1171-1180
-
-
Ellis, E.L.1
Mann, D.A.2
-
103
-
-
0014226518
-
Hepatic cirrhosis. A problem in communication
-
Popper H, Schaffner F Hepatic cirrhosis. A problem in communication. Isr J Med Sci 1968, 4(1):1-7.
-
(1968)
Isr J Med Sci
, vol.4
, Issue.1
, pp. 1-7
-
-
Popper, H.1
Schaffner, F.2
-
104
-
-
0014876077
-
Hepatic fibrosis. Correlation of biochemical and morphologic investigations
-
Popper H, Uenfriend S Hepatic fibrosis. Correlation of biochemical and morphologic investigations. Am J Med 1970, 49:707-721.
-
(1970)
Am J Med
, vol.49
, pp. 707-721
-
-
Popper, H.1
Uenfriend, S.2
-
105
-
-
2942622398
-
Spontaneous recovery from micronodular cirrhosis: evidence for incomplete resolution associated with matrix cross-linking
-
Issa R, Zhou X, Constandinou CM, et al. Spontaneous recovery from micronodular cirrhosis: evidence for incomplete resolution associated with matrix cross-linking. Gastroenterology 2004, 126(7):1795-1808.
-
(2004)
Gastroenterology
, vol.126
, Issue.7
, pp. 1795-1808
-
-
Issa, R.1
Zhou, X.2
Constandinou, C.M.3
-
106
-
-
0035083958
-
Apoptosis of hepatic stellate cells: involvement in resolution of biliary fibrosis and regulation by soluble growth factors
-
Issa R, Williams E, Trim N, et al. Apoptosis of hepatic stellate cells: involvement in resolution of biliary fibrosis and regulation by soluble growth factors. Gut 2001, 48(4):548-557.
-
(2001)
Gut
, vol.48
, Issue.4
, pp. 548-557
-
-
Issa, R.1
Williams, E.2
Trim, N.3
-
107
-
-
0032146551
-
Mechanisms of spontaneous resolution of rat liver fibrosis. Hepatic stellate cell apoptosis and reduced hepatic expression of metalloproteinase inhibitors
-
Iredale JP, Benyon RC, Pickering J, et al. Mechanisms of spontaneous resolution of rat liver fibrosis. Hepatic stellate cell apoptosis and reduced hepatic expression of metalloproteinase inhibitors. J Clin Invest 1998, 102(3):538-549.
-
(1998)
J Clin Invest
, vol.102
, Issue.3
, pp. 538-549
-
-
Iredale, J.P.1
Benyon, R.C.2
Pickering, J.3
-
108
-
-
33746120376
-
Overexpression of Bcl-2 by activated human hepatic stellate cells: resistance to apoptosis as a mechanism of progressive hepatic fibrogenesis in humans
-
Novo E, Marra F, Zamara E, et al. Overexpression of Bcl-2 by activated human hepatic stellate cells: resistance to apoptosis as a mechanism of progressive hepatic fibrogenesis in humans. Gut 2006, 55(8):1174-1182.
-
(2006)
Gut
, vol.55
, Issue.8
, pp. 1174-1182
-
-
Novo, E.1
Marra, F.2
Zamara, E.3
-
109
-
-
39849108604
-
NF-kappaB is a critical regulator of the survival of rodent and human hepatic myofibroblasts
-
Watson MR, Wallace K, Gieling RG, et al. NF-kappaB is a critical regulator of the survival of rodent and human hepatic myofibroblasts. J Hepatol 2008, 48(4):589-597.
-
(2008)
J Hepatol
, vol.48
, Issue.4
, pp. 589-597
-
-
Watson, M.R.1
Wallace, K.2
Gieling, R.G.3
-
110
-
-
11144325650
-
Inhibition of inhibitor of kappaB kinases stimulates hepatic stellate cell apoptosis and accelerated recovery from rat liver fibrosis
-
Oakley F, Meso M, Iredale JP, et al. Inhibition of inhibitor of kappaB kinases stimulates hepatic stellate cell apoptosis and accelerated recovery from rat liver fibrosis. Gastroenterology 2005, 128(1):108-120.
-
(2005)
Gastroenterology
, vol.128
, Issue.1
, pp. 108-120
-
-
Oakley, F.1
Meso, M.2
Iredale, J.P.3
-
111
-
-
0142151091
-
Hepatocytes express nerve growth factor during liver injury: evidence for paracrine regulation of hepatic stellate cell apoptosis
-
Oakley F, Trim N, Constandinou CM, et al. Hepatocytes express nerve growth factor during liver injury: evidence for paracrine regulation of hepatic stellate cell apoptosis. Am J Pathol 2003, 163(5):1849-1858.
-
(2003)
Am J Pathol
, vol.163
, Issue.5
, pp. 1849-1858
-
-
Oakley, F.1
Trim, N.2
Constandinou, C.M.3
-
112
-
-
32044443617
-
Natural killer cells ameliorate liver fibrosis by killing activated stellate cells in NKG2D-dependent and tumor necrosis factor-related apoptosis-inducing ligand-dependent manners
-
Radaeva S, Sun R, Jaruga B, et al. Natural killer cells ameliorate liver fibrosis by killing activated stellate cells in NKG2D-dependent and tumor necrosis factor-related apoptosis-inducing ligand-dependent manners. Gastroenterology 2006, 130(2):435-452.
-
(2006)
Gastroenterology
, vol.130
, Issue.2
, pp. 435-452
-
-
Radaeva, S.1
Sun, R.2
Jaruga, B.3
-
113
-
-
0033817337
-
Hsp72-mediated suppression of c-Jun N-terminal kinase is implicated in development of tolerance to caspase-independent cell death
-
Gabai VL, Yaglom JA, Volloch V, et al. Hsp72-mediated suppression of c-Jun N-terminal kinase is implicated in development of tolerance to caspase-independent cell death. Mol Cell Biol 2000, 20(18):6826-6836.
-
(2000)
Mol Cell Biol
, vol.20
, Issue.18
, pp. 6826-6836
-
-
Gabai, V.L.1
Yaglom, J.A.2
Volloch, V.3
-
114
-
-
84862195154
-
Myofibroblasts revert to an inactive phenotype during regression of liver fibrosis
-
Kisseleva T, Cong M, Paik Y, et al. Myofibroblasts revert to an inactive phenotype during regression of liver fibrosis. Proc Natl Acad Sci USA 2012, 109(24):9448-9453.
-
(2012)
Proc Natl Acad Sci USA
, vol.109
, Issue.24
, pp. 9448-9453
-
-
Kisseleva, T.1
Cong, M.2
Paik, Y.3
-
115
-
-
84939875452
-
Endoplasmic reticulum stress-induced hepatic stellate cell apoptosis through calcium-mediated JNK/P38 MAPK and Calpain/Caspase-12 pathways
-
Huang Y, Li X, Wang Y, et al. Endoplasmic reticulum stress-induced hepatic stellate cell apoptosis through calcium-mediated JNK/P38 MAPK and Calpain/Caspase-12 pathways. Mol Cell Biochem 2014, 394(1-2):1-12.
-
(2014)
Mol Cell Biochem
, vol.394
, Issue.1-2
, pp. 1-12
-
-
Huang, Y.1
Li, X.2
Wang, Y.3
-
116
-
-
84867102077
-
Endoplasmic reticulum stress induces hepatic stellate cell apoptosis and contributes to fibrosis resolution
-
De Minicis S, Candelaresi C, Agostinelli L, et al. Endoplasmic reticulum stress induces hepatic stellate cell apoptosis and contributes to fibrosis resolution. Liver Int 2012, 32(10):1574-1584.
-
(2012)
Liver Int
, vol.32
, Issue.10
, pp. 1574-1584
-
-
De Minicis, S.1
Candelaresi, C.2
Agostinelli, L.3
-
117
-
-
79959988740
-
Cannabidiol causes activated hepatic stellate cell death through a mechanism of endoplasmic reticulum stress-induced apoptosis
-
Lim MP, Devi LA, Rozenfeld R Cannabidiol causes activated hepatic stellate cell death through a mechanism of endoplasmic reticulum stress-induced apoptosis. Cell Death Dis 2011, 2:e170.
-
(2011)
Cell Death Dis
, vol.2
, pp. e170
-
-
Lim, M.P.1
Devi, L.A.2
Rozenfeld, R.3
-
118
-
-
84891600935
-
Blockage of TRPM7 channel induces hepatic stellate cell death through endoplasmic reticulum stress-mediated apoptosis
-
Zhu Y, Men R, Wen M, et al. Blockage of TRPM7 channel induces hepatic stellate cell death through endoplasmic reticulum stress-mediated apoptosis. Life Sci 2014, 94(1):37-44.
-
(2014)
Life Sci
, vol.94
, Issue.1
, pp. 37-44
-
-
Zhu, Y.1
Men, R.2
Wen, M.3
-
119
-
-
49749145668
-
Senescence of activated stellate cells limits liver fibrosis
-
Krizhanovsky V, Yon M, Dickins RA, et al. Senescence of activated stellate cells limits liver fibrosis. Cell 2008, 134(4):657-667.
-
(2008)
Cell
, vol.134
, Issue.4
, pp. 657-667
-
-
Krizhanovsky, V.1
Yon, M.2
Dickins, R.A.3
-
120
-
-
84876291823
-
Non-cell-autonomous tumor suppression by p53
-
Lujambio A, Akkari L, Simon J, et al. Non-cell-autonomous tumor suppression by p53. Cell 2013, 153(2):449-460.
-
(2013)
Cell
, vol.153
, Issue.2
, pp. 449-460
-
-
Lujambio, A.1
Akkari, L.2
Simon, J.3
-
121
-
-
84865564349
-
Interleukin-22 induces hepatic stellate cell senescence and restricts liver fibrosis in mice
-
Kong X, Feng D, Wang H, et al. Interleukin-22 induces hepatic stellate cell senescence and restricts liver fibrosis in mice. Hepatology 2012, 56(3):1150-1159.
-
(2012)
Hepatology
, vol.56
, Issue.3
, pp. 1150-1159
-
-
Kong, X.1
Feng, D.2
Wang, H.3
-
122
-
-
84879888338
-
Obesity-induced gut microbial metabolite promotes liver cancer through senescence secretome
-
Yoshimoto S, Loo TM, Atarashi K, et al. Obesity-induced gut microbial metabolite promotes liver cancer through senescence secretome. Nature 2013, 499(7456):97-101.
-
(2013)
Nature
, vol.499
, Issue.7456
, pp. 97-101
-
-
Yoshimoto, S.1
Loo, T.M.2
Atarashi, K.3
-
123
-
-
84866692545
-
Deactivation of hepatic stellate cells during liver fibrosis resolution in mice
-
e1022
-
Troeger JS, Mederacke I, Gwak GY, et al. Deactivation of hepatic stellate cells during liver fibrosis resolution in mice. Gastroenterology 2012, 143(4):1073-1083. e1022.
-
(2012)
Gastroenterology
, vol.143
, Issue.4
, pp. 1073-1083
-
-
Troeger, J.S.1
Mederacke, I.2
Gwak, G.Y.3
-
124
-
-
84890115630
-
Fructose-1,6-bisphosphate induces phenotypic reversion of activated hepatic stellate cell
-
de Mesquita FC, Bitencourt S, Caberlon E, et al. Fructose-1,6-bisphosphate induces phenotypic reversion of activated hepatic stellate cell. Eur J Pharmacol 2013, 720(1-3):320-325.
-
(2013)
Eur J Pharmacol
, vol.720
, Issue.1-3
, pp. 320-325
-
-
de Mesquita, F.C.1
Bitencourt, S.2
Caberlon, E.3
-
125
-
-
84904673615
-
GIV/Girdin is a central hub for profibrogenic signalling networks during liver fibrosis
-
Lopez-Sanchez I, Dunkel Y, Roh YS, et al. GIV/Girdin is a central hub for profibrogenic signalling networks during liver fibrosis. Nat Commun 2014, 5:4451.
-
(2014)
Nat Commun
, vol.5
, pp. 4451
-
-
Lopez-Sanchez, I.1
Dunkel, Y.2
Roh, Y.S.3
-
126
-
-
65749103808
-
Transcriptional regulation of hepatic stellate cells
-
Mann J, Mann DA Transcriptional regulation of hepatic stellate cells. Adv Drug Deliv Rev 2009, 61(7-8):497-512.
-
(2009)
Adv Drug Deliv Rev
, vol.61
, Issue.7-8
, pp. 497-512
-
-
Mann, J.1
Mann, D.A.2
-
127
-
-
84887999753
-
Epigenetic modifications as new targets for liver disease therapies
-
Zeybel M, Mann DA, Mann J Epigenetic modifications as new targets for liver disease therapies. J Hepatol 2013, 59(6):1349-1353.
-
(2013)
J Hepatol
, vol.59
, Issue.6
, pp. 1349-1353
-
-
Zeybel, M.1
Mann, D.A.2
Mann, J.3
-
128
-
-
84904795250
-
Epigenetics in liver disease
-
Mann DA Epigenetics in liver disease. Hepatology 2014, 60(4):1418-1425.
-
(2014)
Hepatology
, vol.60
, Issue.4
, pp. 1418-1425
-
-
Mann, D.A.1
-
129
-
-
84865559553
-
Histone methyltransferase ASH1 orchestrates fibrogenic gene transcription during myofibroblast transdifferentiation
-
Perugorria MJ, Wilson CL, Zeybel M, et al. Histone methyltransferase ASH1 orchestrates fibrogenic gene transcription during myofibroblast transdifferentiation. Hepatology 2012, 56(3):1129-1139.
-
(2012)
Hepatology
, vol.56
, Issue.3
, pp. 1129-1139
-
-
Perugorria, M.J.1
Wilson, C.L.2
Zeybel, M.3
-
130
-
-
84918552100
-
Myocardin related transcription factor A programs epigenetic activation of hepatic stellate cells
-
Tian W, Hao C, Fan Z, et al. Myocardin related transcription factor A programs epigenetic activation of hepatic stellate cells. J Hepatol 2014, http://dx.doi.org/10.1016/j.jhep.2014.07.029.
-
(2014)
J Hepatol
-
-
Tian, W.1
Hao, C.2
Fan, Z.3
-
131
-
-
75149141045
-
MeCP2 controls an epigenetic pathway that promotes myofibroblast transdifferentiation and fibrosis
-
e701-704
-
Mann J, Chu DC, Maxwell A, et al. MeCP2 controls an epigenetic pathway that promotes myofibroblast transdifferentiation and fibrosis. Gastroenterology 2010, 138(2):705-714. e701-704.
-
(2010)
Gastroenterology
, vol.138
, Issue.2
, pp. 705-714
-
-
Mann, J.1
Chu, D.C.2
Maxwell, A.3
-
132
-
-
79953665837
-
Essential role of MeCP2 in the regulation of myofibroblast differentiation during pulmonary fibrosis
-
Hu B, Gharaee-Kermani M, Wu Z, Phan SH Essential role of MeCP2 in the regulation of myofibroblast differentiation during pulmonary fibrosis. Am J Pathol 2011, 178(4):1500-1508.
-
(2011)
Am J Pathol
, vol.178
, Issue.4
, pp. 1500-1508
-
-
Hu, B.1
Gharaee-Kermani, M.2
Wu, Z.3
Phan, S.H.4
-
133
-
-
80053561101
-
Transplantation of human pericyte progenitor cells improves the repair of infarcted heart through activation of an angiogenic program involving micro-RNA-132
-
Katare R, Riu F, Mitchell K, et al. Transplantation of human pericyte progenitor cells improves the repair of infarcted heart through activation of an angiogenic program involving micro-RNA-132. Circ Res 2011, 109(8):894-906.
-
(2011)
Circ Res
, vol.109
, Issue.8
, pp. 894-906
-
-
Katare, R.1
Riu, F.2
Mitchell, K.3
-
134
-
-
83755162557
-
Myocardin-related transcription factor-A complexes activate type I collagen expression in lung fibroblasts
-
Luchsinger LL, Patenaude CA, Smith BD, Layne MD Myocardin-related transcription factor-A complexes activate type I collagen expression in lung fibroblasts. J Biol Chem 2011, 286(51):44116-44125.
-
(2011)
J Biol Chem
, vol.286
, Issue.51
, pp. 44116-44125
-
-
Luchsinger, L.L.1
Patenaude, C.A.2
Smith, B.D.3
Layne, M.D.4
-
135
-
-
77955173404
-
Myocardin-related transcription factor-a controls myofibroblast activation and fibrosis in response to myocardial infarction
-
Small EM, Thatcher JE, Sutherland LB, et al. Myocardin-related transcription factor-a controls myofibroblast activation and fibrosis in response to myocardial infarction. Circ Res 2010, 107(2):294-304.
-
(2010)
Circ Res
, vol.107
, Issue.2
, pp. 294-304
-
-
Small, E.M.1
Thatcher, J.E.2
Sutherland, L.B.3
-
136
-
-
84883357114
-
Depletion of the transcriptional coactivators megakaryoblastic leukaemia 1 and 2 abolishes hepatocellular carcinoma xenograft growth by inducing oncogene-induced senescence
-
Hampl V, Martin C, Aigner A, et al. Depletion of the transcriptional coactivators megakaryoblastic leukaemia 1 and 2 abolishes hepatocellular carcinoma xenograft growth by inducing oncogene-induced senescence. EMBO Mol Med 2013, 5(9):1367-1382.
-
(2013)
EMBO Mol Med
, vol.5
, Issue.9
, pp. 1367-1382
-
-
Hampl, V.1
Martin, C.2
Aigner, A.3
-
137
-
-
56749184298
-
Reflecting on 25 years with MYC
-
Meyer N, Penn LZ Reflecting on 25 years with MYC. Nat Rev Cancer 2008, 8(12):976-990.
-
(2008)
Nat Rev Cancer
, vol.8
, Issue.12
, pp. 976-990
-
-
Meyer, N.1
Penn, L.Z.2
-
138
-
-
34250800462
-
Amplification of c-myc and cyclin D1 genes in primary and metastatic carcinomas of the liver
-
Takahashi Y, Kawate S, Watanabe M, et al. Amplification of c-myc and cyclin D1 genes in primary and metastatic carcinomas of the liver. Pathol Int 2007, 57(7):437-442.
-
(2007)
Pathol Int
, vol.57
, Issue.7
, pp. 437-442
-
-
Takahashi, Y.1
Kawate, S.2
Watanabe, M.3
-
139
-
-
84879808762
-
Overexpression of c-myc in hepatocytes promotes activation of hepatic stellate cells and facilitates the onset of liver fibrosis
-
Nevzorova YA, Hu W, Cubero FJ, et al. Overexpression of c-myc in hepatocytes promotes activation of hepatic stellate cells and facilitates the onset of liver fibrosis. Biochim Biophys Acta 2013, 1832(10):1765-1775.
-
(2013)
Biochim Biophys Acta
, vol.1832
, Issue.10
, pp. 1765-1775
-
-
Nevzorova, Y.A.1
Hu, W.2
Cubero, F.J.3
-
140
-
-
84894856234
-
Novel RNA oligonucleotide improves liver function and inhibits liver carcinogenesis in vivo
-
Reebye V, Saetrom P, Mintz PJ, et al. Novel RNA oligonucleotide improves liver function and inhibits liver carcinogenesis in vivo. Hepatology 2014, 59(1):216-227.
-
(2014)
Hepatology
, vol.59
, Issue.1
, pp. 216-227
-
-
Reebye, V.1
Saetrom, P.2
Mintz, P.J.3
-
141
-
-
84865554746
-
Cyclin E1 controls proliferation of hepatic stellate cells and is essential for liver fibrogenesis in mice
-
Nevzorova YA, Bangen JM, Hu W, et al. Cyclin E1 controls proliferation of hepatic stellate cells and is essential for liver fibrogenesis in mice. Hepatology 2012, 56(3):1140-1149.
-
(2012)
Hepatology
, vol.56
, Issue.3
, pp. 1140-1149
-
-
Nevzorova, Y.A.1
Bangen, J.M.2
Hu, W.3
-
142
-
-
79960682216
-
Down-regulation of cyclin E1 expression by microRNA-195 accounts for interferon-beta-induced inhibition of hepatic stellate cell proliferation
-
Sekiya Y, Ogawa T, Iizuka M, et al. Down-regulation of cyclin E1 expression by microRNA-195 accounts for interferon-beta-induced inhibition of hepatic stellate cell proliferation. J Cell Physiol 2011, 226(10):2535-2542.
-
(2011)
J Cell Physiol
, vol.226
, Issue.10
, pp. 2535-2542
-
-
Sekiya, Y.1
Ogawa, T.2
Iizuka, M.3
-
143
-
-
84893073453
-
Concurrent deletion of cyclin E1 and cyclin-dependent kinase 2 in hepatocytes inhibits DNA replication and liver regeneration in mice
-
Hu W, Nevzorova YA, Haas U, et al. Concurrent deletion of cyclin E1 and cyclin-dependent kinase 2 in hepatocytes inhibits DNA replication and liver regeneration in mice. Hepatology 2014, 59(2):651-660.
-
(2014)
Hepatology
, vol.59
, Issue.2
, pp. 651-660
-
-
Hu, W.1
Nevzorova, Y.A.2
Haas, U.3
-
144
-
-
84883017889
-
Functions of autophagy in normal and diseased liver
-
Czaja MJ, Ding WX, Donohue TM, et al. Functions of autophagy in normal and diseased liver. Autophagy 2013, 9(8):1131-1158.
-
(2013)
Autophagy
, vol.9
, Issue.8
, pp. 1131-1158
-
-
Czaja, M.J.1
Ding, W.X.2
Donohue, T.M.3
-
145
-
-
81355161371
-
A role for autophagy during hepatic stellate cell activation
-
Thoen LF, Guimaraes EL, Dolle L, et al. A role for autophagy during hepatic stellate cell activation. J Hepatol 2011, 55(6):1353-1360.
-
(2011)
J Hepatol
, vol.55
, Issue.6
, pp. 1353-1360
-
-
Thoen, L.F.1
Guimaraes, E.L.2
Dolle, L.3
-
146
-
-
84877038719
-
Endoplasmic reticulum stress as a pro-fibrotic stimulus
-
Tanjore H, Lawson WE, Blackwell TS Endoplasmic reticulum stress as a pro-fibrotic stimulus. Biochim Biophys Acta 2013, 1832(7):940-947.
-
(2013)
Biochim Biophys Acta
, vol.1832
, Issue.7
, pp. 940-947
-
-
Tanjore, H.1
Lawson, W.E.2
Blackwell, T.S.3
-
147
-
-
84858604270
-
Metabolic reprogramming: a cancer hallmark even warburg did not anticipate
-
Ward PS, Thompson CB Metabolic reprogramming: a cancer hallmark even warburg did not anticipate. Cancer Cell 2012, 21(3):297-308.
-
(2012)
Cancer Cell
, vol.21
, Issue.3
, pp. 297-308
-
-
Ward, P.S.1
Thompson, C.B.2
-
148
-
-
84901464088
-
Novel role of nuclear receptor Rev-erbalpha in hepatic stellate cell activation: potential therapeutic target for liver injury
-
Li T, Eheim AL, Klein S, et al. Novel role of nuclear receptor Rev-erbalpha in hepatic stellate cell activation: potential therapeutic target for liver injury. Hepatology 2014, 59(6):2383-2396.
-
(2014)
Hepatology
, vol.59
, Issue.6
, pp. 2383-2396
-
-
Li, T.1
Eheim, A.L.2
Klein, S.3
-
149
-
-
84868102616
-
Hedgehog controls hepatic stellate cell fate by regulating metabolism
-
e1311
-
Chen Y, Choi SS, Michelotti GA, et al. Hedgehog controls hepatic stellate cell fate by regulating metabolism. Gastroenterology 2012, 143(5):1319-1329. e1311.
-
(2012)
Gastroenterology
, vol.143
, Issue.5
, pp. 1319-1329
-
-
Chen, Y.1
Choi, S.S.2
Michelotti, G.A.3
-
150
-
-
79952301247
-
Liver X receptor signaling is a determinant of stellate cell activation and susceptibility to fibrotic liver disease
-
Beaven SW, Wroblewski K, Wang J, et al. Liver X receptor signaling is a determinant of stellate cell activation and susceptibility to fibrotic liver disease. Gastroenterology 2011, 140(3):1052-1062.
-
(2011)
Gastroenterology
, vol.140
, Issue.3
, pp. 1052-1062
-
-
Beaven, S.W.1
Wroblewski, K.2
Wang, J.3
-
151
-
-
84858796689
-
Transcriptional integration of metabolism by the nuclear sterol-activated receptors LXR and FXR
-
Calkin AC, Tontonoz P Transcriptional integration of metabolism by the nuclear sterol-activated receptors LXR and FXR. Nat Rev Mol Cell Biol 2012, 13(4):213-224.
-
(2012)
Nat Rev Mol Cell Biol
, vol.13
, Issue.4
, pp. 213-224
-
-
Calkin, A.C.1
Tontonoz, P.2
-
152
-
-
7644244675
-
The nuclear receptor SHP mediates inhibition of hepatic stellate cells by FXR and protects against liver fibrosis
-
Fiorucci S, Antonelli E, Rizzo G, et al. The nuclear receptor SHP mediates inhibition of hepatic stellate cells by FXR and protects against liver fibrosis. Gastroenterology 2004, 127(5):1497-1512.
-
(2004)
Gastroenterology
, vol.127
, Issue.5
, pp. 1497-1512
-
-
Fiorucci, S.1
Antonelli, E.2
Rizzo, G.3
-
153
-
-
84901605121
-
Obeticholic acid, a farnesoid X receptor agonist, improves portal hypertension by two distinct pathways in cirrhotic rats
-
Verbeke L, Farre R, Trebicka J, et al. Obeticholic acid, a farnesoid X receptor agonist, improves portal hypertension by two distinct pathways in cirrhotic rats. Hepatology 2014, 59(6):2286-2298.
-
(2014)
Hepatology
, vol.59
, Issue.6
, pp. 2286-2298
-
-
Verbeke, L.1
Farre, R.2
Trebicka, J.3
-
154
-
-
84906498641
-
Alcohol dehydrogenase III exacerbates liver fibrosis by enhancing stellate cell activation and suppressing natural killer cells in mice
-
Yi HS, Lee YS, Byun JS, et al. Alcohol dehydrogenase III exacerbates liver fibrosis by enhancing stellate cell activation and suppressing natural killer cells in mice. Hepatology 2014, http://dx.doi.org/10.1002/hep.27137.
-
(2014)
Hepatology
-
-
Yi, H.S.1
Lee, Y.S.2
Byun, J.S.3
-
155
-
-
84920997249
-
PNPLA3 and liver disease opportunities to unravel mechanisms underlying statistical associations
-
Boursier J, Diehl AM PNPLA3 and liver disease opportunities to unravel mechanisms underlying statistical associations. Hepatology 2014, http://dx.doi.org/10.1002/hep.27445.
-
(2014)
Hepatology
-
-
Boursier, J.1
Diehl, A.M.2
-
156
-
-
84903996547
-
PNPLA3 has retinyl-palmitate lipase activity in human hepatic stellate cells
-
Pirazzi C, Valenti L, Motta BM, et al. PNPLA3 has retinyl-palmitate lipase activity in human hepatic stellate cells. Hum Mol Genet 2014, 23(15):4077-4085.
-
(2014)
Hum Mol Genet
, vol.23
, Issue.15
, pp. 4077-4085
-
-
Pirazzi, C.1
Valenti, L.2
Motta, B.M.3
-
157
-
-
80053612479
-
Hepatic free cholesterol accumulates in obese, diabetic mice and causes nonalcoholic steatohepatitis
-
e1391-1395
-
Van Rooyen DM, Larter CZ, Haigh WG, et al. Hepatic free cholesterol accumulates in obese, diabetic mice and causes nonalcoholic steatohepatitis. Gastroenterology 2011, 141(4):1393-1403. e1391-1395.
-
(2011)
Gastroenterology
, vol.141
, Issue.4
, pp. 1393-1403
-
-
Van Rooyen, D.M.1
Larter, C.Z.2
Haigh, W.G.3
-
158
-
-
83755163159
-
A high-cholesterol diet exacerbates liver fibrosis in mice via accumulation of free cholesterol in hepatic stellate cells
-
e110
-
Teratani T, Tomita K, Suzuki T, et al. A high-cholesterol diet exacerbates liver fibrosis in mice via accumulation of free cholesterol in hepatic stellate cells. Gastroenterology 2012, 142(1):152-164. e110.
-
(2012)
Gastroenterology
, vol.142
, Issue.1
, pp. 152-164
-
-
Teratani, T.1
Tomita, K.2
Suzuki, T.3
-
159
-
-
84894875873
-
Free cholesterol accumulation in hepatic stellate cells: mechanism of liver fibrosis aggravation in nonalcoholic steatohepatitis in mice
-
Tomita K, Teratani T, Suzuki T, et al. Free cholesterol accumulation in hepatic stellate cells: mechanism of liver fibrosis aggravation in nonalcoholic steatohepatitis in mice. Hepatology 2014, 59(1):154-169.
-
(2014)
Hepatology
, vol.59
, Issue.1
, pp. 154-169
-
-
Tomita, K.1
Teratani, T.2
Suzuki, T.3
-
160
-
-
84902685435
-
Acyl-CoA:cholesterol acyltransferase 1 mediates liver fibrosis by regulating free cholesterol accumulation in hepatic stellate cells
-
Tomita K, Teratani T, Suzuki T, et al. Acyl-CoA:cholesterol acyltransferase 1 mediates liver fibrosis by regulating free cholesterol accumulation in hepatic stellate cells. J Hepatol 2014, 61(1):98-106.
-
(2014)
J Hepatol
, vol.61
, Issue.1
, pp. 98-106
-
-
Tomita, K.1
Teratani, T.2
Suzuki, T.3
-
161
-
-
84879132692
-
Pharmacological cholesterol lowering reverses fibrotic NASH in obese, diabetic mice with metabolic syndrome
-
Van Rooyen DM, Gan LT, Yeh MM, et al. Pharmacological cholesterol lowering reverses fibrotic NASH in obese, diabetic mice with metabolic syndrome. J Hepatol 2013, 59(1):144-152.
-
(2013)
J Hepatol
, vol.59
, Issue.1
, pp. 144-152
-
-
Van Rooyen, D.M.1
Gan, L.T.2
Yeh, M.M.3
-
162
-
-
78751585439
-
Hedgehog signaling in the liver
-
Omenetti A, Choi S, Michelotti G, Diehl AM Hedgehog signaling in the liver. J Hepatol 2011, 54(2):366-373.
-
(2011)
J Hepatol
, vol.54
, Issue.2
, pp. 366-373
-
-
Omenetti, A.1
Choi, S.2
Michelotti, G.3
Diehl, A.M.4
-
163
-
-
84890567500
-
The intrahepatic signalling niche of hedgehog is defined by primary cilia positive cells during chronic liver injury
-
Grzelak CA, Martelotto LG, Sigglekow ND, et al. The intrahepatic signalling niche of hedgehog is defined by primary cilia positive cells during chronic liver injury. J Hepatol 2014, 60(1):143-151.
-
(2014)
J Hepatol
, vol.60
, Issue.1
, pp. 143-151
-
-
Grzelak, C.A.1
Martelotto, L.G.2
Sigglekow, N.D.3
-
164
-
-
84920984254
-
Treatment response in the PIVENS trial is associated with decreased hedgehog pathway activity
-
Guy CD, Suzuki A, Abdelmalek MF, Burchette JL, Diehl AM Treatment response in the PIVENS trial is associated with decreased hedgehog pathway activity. Hepatology 2014, http://dx.doi.org/10.1002/hep.27235.
-
(2014)
Hepatology
-
-
Guy, C.D.1
Suzuki, A.2
Abdelmalek, M.F.3
Burchette, J.L.4
Diehl, A.M.5
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