메뉴 건너뛰기




Volumn 6, Issue 7, 2011, Pages

A transgenic model for conditional induction and rescue of portal hypertension reveals a role of VEGF-mediated regulation of sinusoidal fenestrations

Author keywords

[No Author keywords available]

Indexed keywords

VASCULOTROPIN; VASCULOTROPIN A; VASCULOTROPIN RECEPTOR 1;

EID: 79960109597     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0021478     Document Type: Article
Times cited : (43)

References (26)
  • 1
    • 35948954244 scopus 로고    scopus 로고
    • Hepatic stellate cells: protean, multifunctional, and enigmatic cells of the liver
    • Friedman SL, (2008) Hepatic stellate cells: protean, multifunctional, and enigmatic cells of the liver. Physiol Rev 88: 125-172.
    • (2008) Physiol Rev , vol.88 , pp. 125-172
    • Friedman, S.L.1
  • 3
    • 35848949969 scopus 로고    scopus 로고
    • Vascular deterioration in cirrhosis: the big picture
    • Bosch J, (2007) Vascular deterioration in cirrhosis: the big picture. J Clin Gastroenterol 41 (Suppl 3): S247-253.
    • (2007) J Clin Gastroenterol , vol.41 , Issue.SUPPL. 3
    • Bosch, J.1
  • 4
    • 0034806854 scopus 로고    scopus 로고
    • VEGF can act as vascular permeability factor in the hepatic sinusoids through upregulation of porosity of endothelial cells
    • Funyu J, Mochida S, Inao M, Matsui A, Fujiwara K, (2001) VEGF can act as vascular permeability factor in the hepatic sinusoids through upregulation of porosity of endothelial cells. Biochem Biophys Res Commun 280: 481-485.
    • (2001) Biochem Biophys Res Commun , vol.280 , pp. 481-485
    • Funyu, J.1    Mochida, S.2    Inao, M.3    Matsui, A.4    Fujiwara, K.5
  • 5
    • 0348013133 scopus 로고    scopus 로고
    • Vascular endothelial growth factor increases fenestral permeability in hepatic sinusoidal endothelial cells
    • Yokomori H, Oda M, Yoshimura K, Nagai T, Ogi M, et al. (2003) Vascular endothelial growth factor increases fenestral permeability in hepatic sinusoidal endothelial cells. Liver Int 23: 467-475.
    • (2003) Liver Int , vol.23 , pp. 467-475
    • Yokomori, H.1    Oda, M.2    Yoshimura, K.3    Nagai, T.4    Ogi, M.5
  • 6
    • 23844555148 scopus 로고    scopus 로고
    • VEGF is crucial for the hepatic vascular development required for lipoprotein uptake
    • Carpenter B, Lin Y, Stoll S, Raffai RL, McCuskey R, et al. (2005) VEGF is crucial for the hepatic vascular development required for lipoprotein uptake. Development 132: 3293-3303.
    • (2005) Development , vol.132 , pp. 3293-3303
    • Carpenter, B.1    Lin, Y.2    Stoll, S.3    Raffai, R.L.4    McCuskey, R.5
  • 7
    • 32944466693 scopus 로고    scopus 로고
    • Cellular changes in normal blood capillaries undergoing regression after inhibition of VEGF signaling
    • Baffert F, Le T, Sennino B, Thurston G, Kuo CJ, et al. (2006) Cellular changes in normal blood capillaries undergoing regression after inhibition of VEGF signaling. Am J Physiol Heart Circ Physiol 290: H547-559.
    • (2006) Am J Physiol Heart Circ Physiol , vol.290
    • Baffert, F.1    Le, T.2    Sennino, B.3    Thurston, G.4    Kuo, C.J.5
  • 8
    • 77955853856 scopus 로고    scopus 로고
    • Hepatic endothelial dysfunction and abnormal angiogenesis: new targets in the treatment of portal hypertension
    • Bosch J, Abraldes JG, Fernandez M, Garcia-Pagan JC. Hepatic endothelial dysfunction and abnormal angiogenesis: new targets in the treatment of portal hypertension. J Hepatol 53: 558-567.
    • J Hepatol , vol.53 , pp. 558-567
    • Bosch, J.1    Abraldes, J.G.2    Fernandez, M.3    Garcia-Pagan, J.C.4
  • 9
    • 0029763587 scopus 로고    scopus 로고
    • Doxycycline-mediated quantitative and tissue-specific control of gene expression in transgenic mice
    • Kistner A, Gossen M, Zimmermann F, Jerecic J, Ullmer C, et al. (1996) Doxycycline-mediated quantitative and tissue-specific control of gene expression in transgenic mice. Proc Natl Acad Sci U S A 93: 10933-10938.
    • (1996) Proc Natl Acad Sci U S A , vol.93 , pp. 10933-10938
    • Kistner, A.1    Gossen, M.2    Zimmermann, F.3    Jerecic, J.4    Ullmer, C.5
  • 10
    • 38349138807 scopus 로고    scopus 로고
    • Transgenic system for conditional induction and rescue of chronic myocardial hibernation provides insights into genomic programs of hibernation
    • May D, Gilon D, Djonov V, Itin A, Lazarus A, et al. (2008) Transgenic system for conditional induction and rescue of chronic myocardial hibernation provides insights into genomic programs of hibernation. Proc Natl Acad Sci U S A 105: 282-287.
    • (2008) Proc Natl Acad Sci U S A , vol.105 , pp. 282-287
    • May, D.1    Gilon, D.2    Djonov, V.3    Itin, A.4    Lazarus, A.5
  • 11
    • 0037090776 scopus 로고    scopus 로고
    • Conditional switching of VEGF provides new insights into adult neovascularization and pro-angiogenic therapy
    • Dor Y, Djonov V, Abramovitch R, Itin A, Fishman GI, et al. (2002) Conditional switching of VEGF provides new insights into adult neovascularization and pro-angiogenic therapy. Embo J 21: 1939-1947.
    • (2002) Embo J , vol.21 , pp. 1939-1947
    • Dor, Y.1    Djonov, V.2    Abramovitch, R.3    Itin, A.4    Fishman, G.I.5
  • 12
    • 0033964164 scopus 로고    scopus 로고
    • Intussusceptive angiogenesis: its role in embryonic vascular network formation
    • Djonov V, Schmid M, Tschanz SA, Burri PH, (2000) Intussusceptive angiogenesis: its role in embryonic vascular network formation. Circ Res 86: 286-292.
    • (2000) Circ Res , vol.86 , pp. 286-292
    • Djonov, V.1    Schmid, M.2    Tschanz, S.A.3    Burri, P.H.4
  • 14
    • 0028936263 scopus 로고
    • Lipoproteins and the liver sieve: the role of the fenestrated sinusoidal endothelium in lipoprotein metabolism, atherosclerosis, and cirrhosis
    • Fraser R, Dobbs BR, Rogers GW, (1995) Lipoproteins and the liver sieve: the role of the fenestrated sinusoidal endothelium in lipoprotein metabolism, atherosclerosis, and cirrhosis. Hepatology 21: 863-874.
    • (1995) Hepatology , vol.21 , pp. 863-874
    • Fraser, R.1    Dobbs, B.R.2    Rogers, G.W.3
  • 15
    • 77950458025 scopus 로고    scopus 로고
    • Expression of LYVE-1 in sinusoidal endothelium is reduced in chronically inflamed human livers
    • Arimoto J, Ikura Y, Suekane T, Nakagawa M, Kitabayashi C, et al. (2009) Expression of LYVE-1 in sinusoidal endothelium is reduced in chronically inflamed human livers. J Gastroenterol.
    • (2009) J Gastroenterol
    • Arimoto, J.1    Ikura, Y.2    Suekane, T.3    Nakagawa, M.4    Kitabayashi, C.5
  • 18
    • 67650461998 scopus 로고    scopus 로고
    • Management and treatment of patients with cirrhosis and portal hypertension: recommendations from the Department of Veterans Affairs Hepatitis C Resource Center Program and the National Hepatitis C Program
    • Garcia-Tsao G, Lim JK, (2009) Management and treatment of patients with cirrhosis and portal hypertension: recommendations from the Department of Veterans Affairs Hepatitis C Resource Center Program and the National Hepatitis C Program. Am J Gastroenterol 104: 1802-1829.
    • (2009) Am J Gastroenterol , vol.104 , pp. 1802-1829
    • Garcia-Tsao, G.1    Lim, J.K.2
  • 19
  • 20
    • 0027980356 scopus 로고
    • A new communication system between hepatocytes and sinusoidal endothelial cells in liver through vascular endothelial growth factor and Flt tyrosine kinase receptor family (Flt-1 and KDR/Flk-1)
    • Yamane A, Seetharam L, Yamaguchi S, Gotoh N, Takahashi T, et al. (1994) A new communication system between hepatocytes and sinusoidal endothelial cells in liver through vascular endothelial growth factor and Flt tyrosine kinase receptor family (Flt-1 and KDR/Flk-1). Oncogene 9: 2683-2690.
    • (1994) Oncogene , vol.9 , pp. 2683-2690
    • Yamane, A.1    Seetharam, L.2    Yamaguchi, S.3    Gotoh, N.4    Takahashi, T.5
  • 21
    • 79960130652 scopus 로고    scopus 로고
    • Interim safety-analysis of the AVATACE-1 trial (Bevacizumab as inhibitor of collateral tumor-vessel growth during trasarterial chemoembolisation (TACE) for hepatocellular carcinoma - a double blind randomized placebo-controlled pilot trial)
    • Abstract EASL 2010
    • Ulbrich G, Pinter M, Reiberger T, Ferlitsch A, Sieghart W, et al. (2010) Interim safety-analysis of the AVATACE-1 trial (Bevacizumab as inhibitor of collateral tumor-vessel growth during trasarterial chemoembolisation (TACE) for hepatocellular carcinoma- a double blind randomized placebo-controlled pilot trial). Abstract EASL 2010, Journal of Hepatology Supplement.
    • (2010) Journal of Hepatology Supplement
    • Ulbrich, G.1    Pinter, M.2    Reiberger, T.3    Ferlitsch, A.4    Sieghart, W.5
  • 23
    • 77954976056 scopus 로고    scopus 로고
    • Neuropilin-1 promotes cirrhosis of the rodent and human liver by enhancing PDGF/TGF-beta signaling in hepatic stellate cells
    • Cao S, Yaqoob U, Das A, Shergill U, Jagavelu K, et al. (2010) Neuropilin-1 promotes cirrhosis of the rodent and human liver by enhancing PDGF/TGF-beta signaling in hepatic stellate cells. J Clin Invest 120: 2379-2394.
    • (2010) J Clin Invest , vol.120 , pp. 2379-2394
    • Cao, S.1    Yaqoob, U.2    Das, A.3    Shergill, U.4    Jagavelu, K.5
  • 24
    • 0024852111 scopus 로고
    • Activation of cultured rat hepatic lipocytes by Kupffer cell conditioned medium. Direct enhancement of matrix synthesis and stimulation of cell proliferation via induction of platelet-derived growth factor receptors
    • Friedman SL, Arthur MJ, (1989) Activation of cultured rat hepatic lipocytes by Kupffer cell conditioned medium. Direct enhancement of matrix synthesis and stimulation of cell proliferation via induction of platelet-derived growth factor receptors. J Clin Invest 84: 1780-1785.
    • (1989) J Clin Invest , vol.84 , pp. 1780-1785
    • Friedman, S.L.1    Arthur, M.J.2
  • 25
    • 33847363203 scopus 로고    scopus 로고
    • Models of liver fibrosis: exploring the dynamic nature of inflammation and repair in a solid organ
    • Iredale JP, (2007) Models of liver fibrosis: exploring the dynamic nature of inflammation and repair in a solid organ. J Clin Invest 117: 539-548.
    • (2007) J Clin Invest , vol.117 , pp. 539-548
    • Iredale, J.P.1
  • 26
    • 0028170153 scopus 로고
    • Induction of beta-platelet-derived growth factor receptor in rat hepatic lipocytes during cellular activation in vivo and in culture
    • Wong L, Yamasaki G, Johnson RJ, Friedman SL, (1994) Induction of beta-platelet-derived growth factor receptor in rat hepatic lipocytes during cellular activation in vivo and in culture. J Clin Invest 94: 1563-1569.
    • (1994) J Clin Invest , vol.94 , pp. 1563-1569
    • Wong, L.1    Yamasaki, G.2    Johnson, R.J.3    Friedman, S.L.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.