Free cholesterol accumulation in hepatic stellate cells: Mechanism of liver fibrosis aggravation in nonalcoholic steatohepatitis in mice

Hepatology

Volumn 59, Issue 1, 2014, Pages 154-169

  Tomita, Kengo ^a,b   Teratani, Toshiaki ^b   Suzuki, Takahiro ^b   Shimizu, Motonori ^a   Sato, Hirokazu ^a   Narimatsu, Kazuyuki ^a   Okada, Yoshikiyo ^a   Kurihara, Chie ^a   Irie, Rie ^c   Yokoyama, Hirokazu ^b   Shimamura, Katsuyoshi ^b   Usui, Shingo ^a,b   Ebinuma, Hirotoshi ^b   Saito, Hidetsugu ^d   Watanabe, Chikako ^a   Komoto, Shunsuke ^a   Kawaguchi, Atsushi ^a   Nagao, Shigeaki ^a   Sugiyama, Kazuo ^b   Hokari, Ryota ^a   Kanai, Takanori ^b   Miura, Soichiro ^a   Hibi, Toshifumi ^b   more..

^a NATIONAL DEFENSE MEDICAL COLLEGE   (Japan)

^b KEIO UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^c KAWASAKI MUNICIPAL HOSPITAL   (Japan)

^d KEIO UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

ACTIVIN MEMBRANE BOUND INHIBITOR; BONE MORPHOGENETIC PROTEIN; CHOLESTEROL; CHOLINE; METHIONINE; MICRORNA; MICRORNA 33A; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA; PROTEIN; PROTEIN INHIBITOR; STEROL REGULATORY ELEMENT BINDING PROTEIN 2; STEROL REGULATORY ELEMENT BINDING PROTEIN CLEAVAGE ACTIVATING PROTEIN; TOLL LIKE RECEPTOR 4; TRANSFORMING GROWTH FACTOR BETA; UNCLASSIFIED DRUG; BAMBI PROTEIN, MOUSE; INSIG1 PROTEIN, MOUSE; LOW DENSITY LIPOPROTEIN RECEPTOR; MEMBRANE PROTEIN; MESSENGER RNA; MIRN33 MICRORNA, MOUSE; SREBF2 PROTEIN, MOUSE; TLR4 PROTEIN, MOUSE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL ACTIVATION; CHOLESTEROL DIET; CONTROLLED STUDY; DOWN REGULATION; FEEDBACK SYSTEM; GENE EXPRESSION; HOMEOSTASIS; INSULIN INDUCED GENE; KUPFFER CELL; LIPID STORAGE; LIVER CELL DAMAGE; LIVER FIBROSIS; MACROPHAGE ACTIVATION; MALE; MOUSE; MOUSE MODEL; NONALCOHOLIC FATTY LIVER; NONHUMAN; PATHOPHYSIOLOGY; PRIORITY JOURNAL; PROTEIN EXPRESSION; SENSITIZATION; SIGNAL TRANSDUCTION; STELLATE CELL; UPREGULATION; ANIMAL; C57BL MOUSE; DISEASE MODEL; FATTY LIVER; LIVER CIRRHOSIS; METABOLISM; COMPLICATION;

ANIMALS; CHOLESTEROL; DISEASE MODELS, ANIMAL; DOWN-REGULATION; FATTY LIVER; HEPATIC STELLATE CELLS; LIVER CIRRHOSIS; MACROPHAGE ACTIVATION; MALE; MEMBRANE PROTEINS; MICE; MICE, INBRED C57BL; MICRORNAS; PPAR GAMMA; RECEPTORS, LDL; RNA, MESSENGER; SIGNAL TRANSDUCTION; STEROL REGULATORY ELEMENT BINDING PROTEIN 2; TOLL-LIKE RECEPTOR 4; TRANSFORMING GROWTH FACTOR BETA; UP-REGULATION;

EID: 84894875873     PISSN: 02709139     EISSN: 15273350     Source Type: Journal    
DOI: 10.1002/hep.26604     Document Type: Article

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