Concurrent deletion of cyclin E1 and cyclin-dependent kinase 2 in hepatocytes inhibits DNA replication and liver regeneration in mice

Hepatology

Volumn 59, Issue 2, 2014, Pages 651-660

  Hu, Wei ^a   Nevzorova, Yulia A ^a   Haas, Ute ^a   Moro, Nives ^a,d   Sicinski, Piotr ^b   Geng, Yan ^b   Barbacid, Mariano ^c   Trautwein, Christian ^a   Liedtke, Christian ^a  

^a UNIVERSITY HOSPITAL RWTH AACHEN   (Germany)

^b HARVARD MEDICAL SCHOOL   (United States)

^c Centro Nacional de Investigaciones Oncológicas   (Spain)

^d UNIVERSITY HOSPITAL OF COLOGNE   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

CYCLIN A2; CYCLIN DEPENDENT KINASE 2; CYCLIN E; CYCLIN E1; CYCLIN E2; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CELL CYCLE; CELL CYCLE PROGRESSION; CELL CYCLE S PHASE; CELL DEATH; CHROMATIN; COMPARATIVE STUDY; CONTROLLED STUDY; DNA CONTENT; DNA REPLICATION; DNA SYNTHESIS; DOWN REGULATION; ENZYME ACTIVITY; GENE DELETION; GENE EXPRESSION; GENE INACTIVATION; GENE INDUCTION; LIVER; LIVER CELL; LIVER REGENERATION; MOUSE; NONHUMAN; PARTIAL HEPATECTOMY; PHOSPHORYLATION; PRIORITY JOURNAL; PROMOTER REGION; UPREGULATION;

ANIMALS; APOPTOSIS; CELL CYCLE; CELLS, CULTURED; CHROMATIN; CYCLIN E; CYCLIN-DEPENDENT KINASE 2; CYCLINS; DNA REPLICATION; FEMALE; HEPATOCYTES; HOMEOSTASIS; LIVER REGENERATION; MALE; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MODELS, ANIMAL; ONCOGENE PROTEINS; S PHASE;

EID: 84893073453     PISSN: 02709139     EISSN: 15273350     Source Type: Journal    
DOI: 10.1002/hep.26584     Document Type: Article

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