Intracellular reactive oxygen species are required for directional migration of resident and bone marrow-derived hepatic pro-fibrogenic cells

Journal of Hepatology

Volumn 54, Issue 5, 2011, Pages 964-974

  Novo, Erica ^a   Busletta, Chiara ^a   Bonzo, Lorenzo Valfrè Di ^a   Povero, Davide ^a   Paternostro, Claudia ^a   Mareschi, Katia ^b,c   Ferrero, Ivana ^b,c   David, Ezio ^d   Bertolani, Cristiana ^e   Caligiuri, Alessandra ^e   Cannito, Stefania ^a   Tamagno, Elena ^a   Compagnone, Alessandra ^a   Colombatto, Sebastiano ^a   Marra, Fabio ^e   Fagioli, Franca ^b   Pinzani, Massimo ^e   Parola, Maurizio ^a,c  

^a Centro Interuniversitario di Fisiopatologia Epatica   (Italy)

^b REGINA MARGHERITA CHILDREN S HOSPITAL   (Italy)

^c UNIVERSITY OF TURIN   (Italy)

^d MOLINETTE HOSPITAL   (Italy)

^e UNIVERSITY OF FLORENCE   (Italy)

Author keywords

Chemotaxis; Hepatic stellate cells; Liver fibrogenesis; Mesenchymal stem cells; Reactive oxygen species

Indexed keywords

2,3 DIMETHOXY 1,4 NAPHTHOQUINONE; ALPHA SMOOTH MUSCLE ACTIN; CHEMOATTRACTANT; HYDROGEN PEROXIDE; MENADIONE; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; MITOGEN ACTIVATED PROTEIN KINASE P38; POLYPEPTIDE; REACTIVE OXYGEN METABOLITE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE; STRESS ACTIVATED PROTEIN KINASE 1; SUPEROXIDE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BONE MARROW; CELL MIGRATION; CELL STRUCTURE; CHEMOKINESIS; CHEMOTAXIS; CHRONIC LIVER DISEASE; CONTROLLED STUDY; ENGRAFTMENT; ENZYME ACTIVATION; ENZYME INDUCTION; ENZYME PHOSPHORYLATION; FIBROGENESIS; GENE SILENCING; HUMAN; HUMAN CELL; HUMAN TISSUE; IN VIVO STUDY; INTRACELLULAR SIGNALING; LIVER CELL; LIVER CIRRHOSIS; LIVER FIBROSIS; LIVER INJURY; MALE; MESENCHYMAL STEM CELL; MOLECULAR BIOLOGY; MYOFIBROBLAST; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; RAT; STELLATE CELL; WOUND HEALING;

BONE MARROW CELLS; CELL MOVEMENT; CELLS, CULTURED; CHEMOTACTIC FACTORS; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; HEPATIC STELLATE CELLS; HEPATITIS C, CHRONIC; HUMANS; INTERCELLULAR SIGNALING PEPTIDES AND PROTEINS; JNK MITOGEN-ACTIVATED PROTEIN KINASES; LIVER CIRRHOSIS; MAP KINASE SIGNALING SYSTEM; MESENCHYMAL STEM CELLS; REACTIVE OXYGEN SPECIES;

EID: 79954558900     PISSN: 01688278     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jhep.2010.09.022     Document Type: Article

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