Increased contractility of hepatic stellate cells in cirrhosis is mediated by enhanced Ca2+-dependent and Ca2+-sensitization pathways

American Journal of Physiology - Gastrointestinal and Liver Physiology

Volumn 300, Issue 6, 2011, Pages

  Iizuka, Masateru ^a   Murata, Takahisa ^a   Hori, Masatoshi ^a   Ozaki, Hiroshi ^a  

^a UNIVERSITY OF TOKYO   (Japan)

Author keywords

Cpi 17; Endothelin 1; Myosin light chain kinase; Myosin light chain phosphatase targeting subunit 1; Myosin light chain phosphorylation; Protein kinase c; Rho kinase

Indexed keywords

4 (1 AMINOETHYL) N (4 PYRIDYL)CYCLOHEXANECARBOXAMIDE; ALPHA SMOOTH MUSCLE ACTIN; CALCIUM ION; CONTRACTILE PROTEIN; ENDOTHELIN 1; MYOSIN LIGHT CHAIN; MYOSIN LIGHT CHAIN KINASE; REGULATOR PROTEIN; RHO KINASE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL ACTIVATION; CELL FUNCTION; CONTROLLED STUDY; IN VITRO STUDY; IN VIVO STUDY; LIVER CIRRHOSIS; MALE; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; RAT; STELLATE CELL; WESTERN BLOTTING;

ACTINS; AMIDES; ANIMALS; BLOTTING, WESTERN; CALCIUM; CALCIUM SIGNALING; CELL SHAPE; CELLS, CULTURED; ENDOTHELIN-1; HEPATIC STELLATE CELLS; INDOLES; LIVER; LIVER CIRRHOSIS, EXPERIMENTAL; MALE; MALEIMIDES; MUSCLE PROTEINS; MYOSIN LIGHT CHAINS; MYOSIN-LIGHT-CHAIN KINASE; PHOSPHOPROTEINS; PHOSPHORYLATION; PROTEIN KINASE C; PROTEIN KINASE INHIBITORS; PROTEIN PHOSPHATASE 1; PYRIDINES; RATS; RATS, SPRAGUE-DAWLEY; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RHO-ASSOCIATED KINASES; TIME FACTORS;

EID: 79957943503     PISSN: 01931857     EISSN: 15221547     Source Type: Journal    
DOI: 10.1152/ajpgi.00350.2010     Document Type: Article

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