Smoothened is a master regulator of adult liver repair

Journal of Clinical Investigation

Volumn 123, Issue 6, 2013, Pages 2380-2394

  Michelotti, Gregory A ^a   Xie, Guanhua ^a   Swiderska, Marzena ^a   Choi, Steve S ^a   Karaca, Gamze ^a   Krüger, Leandi ^a   Premont, Richard ^a   Yang, Liu ^a   Syn, Wing Kin ^a,b   Metzger, Daniel ^c   Diehl, Anna Mae ^a  

^a DUKE UNIVERSITY MEDICAL CENTER   (United States)

^b INSTITUTE OF HEPATOLOGY   (United Kingdom)

^c INSTITUT DE GÉNÉTIQUE ET DE BIOLOGIE MOLÉCULAIRE ET CELLULAIRE   (France)

Author keywords

[No Author keywords available]

Indexed keywords

ALANINE AMINOTRANSFERASE; ALPHA SMOOTH MUSCLE ACTIN; CRE RECOMBINASE; CYCLIN D1; DESMIN; DESMOPLAKIN; ELASTIN; OSTEOPONTIN; SECRETED FRIZZLED RELATED PROTEIN 1; SMOOTHENED PROTEIN; SONIC HEDGEHOG PROTEIN; TRANSCRIPTION FACTOR SNAIL; TRANSCRIPTION FACTOR SOX9; UVOMORULIN;

ALANINE AMINOTRANSFERASE BLOOD LEVEL; ANIMAL EXPERIMENT; ANTIBODY SPECIFICITY; ARTICLE; CELL CYCLE PROGRESSION; CONTROLLED STUDY; EMBRYO DEVELOPMENT; EPITHELIAL MESENCHYMAL TRANSITION; GENE EXPRESSION; GENE REARRANGEMENT; IMMUNOHISTOCHEMISTRY; LIVER; LIVER CELL DAMAGE; LIVER FIBROSIS; LIVER INJURY; LIVER REGENERATION; MOUSE; NONHUMAN; PARTIAL HEPATECTOMY; PHENOTYPE; PLASTICITY; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; TISSUE REPAIR;

ADULT STEM CELLS; ANIMALS; BIOLOGICAL MARKERS; CELLS, CULTURED; CHOLESTASIS; HEDGEHOG PROTEINS; HEPATIC STELLATE CELLS; HUMANS; LIVER; LIVER CIRRHOSIS; MALE; MICE; MICE, INBRED C57BL; MICE, TRANSGENIC; MYOFIBROBLASTS; RATS; RECEPTORS, G-PROTEIN-COUPLED; REGENERATION; SIGNAL TRANSDUCTION; WOUND HEALING;

EID: 84878527104     PISSN: 00219738     EISSN: 15588238     Source Type: Journal    
DOI: 10.1172/JCI66904     Document Type: Article

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