ADAM metallopeptidase with thrombospondin type 1 motif 2 inactivation reduces the extent and stability of carbon tetrachloride-lnduced hepatic fibrosis in mice

Hepatology

Volumn 46, Issue 5, 2007, Pages 1620-1631

  Kesteloot, Frédéric ^a   Desmoulière, Alexis ^b,c   Leclercq, Isabelle ^d   Thiry, Marc ^a   Arrese, Jorge E ^e   Prockop, Darwin J ^f   Lapière, Charles M ^a   Nusgens, Betty V ^a   Colige, Alain ^a,g  

^a UNIVERSITY OF LIÈGE   (Belgium)

^b INSERM   (France)

^c UNIVERSITY OF LIMOGES   (France)

^d UNIVERSITÉ CATHOLIQUE DE LOUVAIN   (Belgium)

^e UNIVERSITY OF LIÈGE   (Belgium)

^f TULANE UNIVERSITY HEALTH SCIENCES CENTER   (United States)

^g Tour de Pathologie   (Belgium)

Author keywords

[No Author keywords available]

Indexed keywords

ADAM METALLOPEPTIDASE WITH THROMBOSPONDIN TYPE 1 MOTIF 2; CARBON TETRACHLORIDE; COLLAGEN TYPE 1; COLLAGEN TYPE 3; METALLOPROTEINASE; UNCLASSIFIED DRUG; ADAM METALLOPEPTIDASE WITH THROMBOSPONDIN TYPE 1 MOTIF 2 PROTEIN; ADAM PROTEIN; THROMBOSPONDIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; ENZYME ANALYSIS; ENZYME INHIBITION; GENE EXPRESSION; IMMUNOCHEMISTRY; LIVER FIBROSIS; LIVER INJURY; MOUSE; NONHUMAN; PRIORITY JOURNAL; ANIMAL CELL; CARBON TETRACHLORIDE-INDUCED LIVER FIBROSIS; COMPARATIVE STUDY; FEMALE; IN VIVO STUDY; INVESTIGATIVE PROCEDURES; LONG TERM CARE; REVERTANT; SINGLE DRUG DOSE; WILD TYPE;

ADAM PROTEINS; ANIMALS; CARBON TETRACHLORIDE; COLLAGEN; GENE EXPRESSION REGULATION; INJECTIONS, INTRAPERITONEAL; LIVER; LIVER CIRRHOSIS; MICE; MICE, KNOCKOUT; PROCOLLAGEN N-ENDOPEPTIDASE;

EID: 36348984906     PISSN: 02709139     EISSN: None     Source Type: Journal    
DOI: 10.1002/hep.21868     Document Type: Article

References (41)

1. Schuppan D. Structure of the extracellular matrix in normal and fibrotic liver: collagens and glycoproteins. Semin Liver Dis 1990;10:1-10.
2. Desmet VJ, Roskams T. Cirrhosis reversal: a duel between dogma and myth. J Hepatol 2004;40:860-867.
3. Olaso E, Friedman SL. Molecular regulation of hepatic fibrogenesis. J Hepatol 1998;29:836-847.
4. Bissel DM, Maher JJ. Hepatic fibrosis and cirrhosis. In: Zakim D, Boyer TD, eds. Hepatology: A Textbook of Liver Disease. Philadelphia, PA: Saunders, 1996:506-525.
5. Bataller R, Brenner DA. Liver fibrosis. J Clin Invest 2005;115:209-218.
6. Tsukada S, Parsons CJ, Rippe RA. Mechanisms of liver fibrosis. Clin Chim Acta 2006;364:33-60.
7. Li SW, Sieron AL, Fertala A, Hojima Y, Arnold WV, Prockop DJ. The C-proteinase that processes procollagens to fibrillar collagens is identical to the protein previously identified as bone morphogenic protein-1. Proc Natl Acad Sci U S A 1996;93:5127-5130.
8. Kessler E, Takahara K, Biniaminov L, Brusel M, Greenspan DS. Bone morphogenetic protein-1: the type I procollagen C-proteinase. Science 1996;271:360-362.
9. Lapiere CM, Lenaers A, Kohn LD. Procollagen peptidase: an enzyme excising the coordination peptides of procollagen. Proc Natl Acad Sci U S A 1971;68:3054-3058.
10. Colige A, Li SW, Sieron AL, Nusgens BV, Prockop DJ, Lapiere CM. cDNA cloning and expression of bovine procollagen I N-proteinase: a new member of the superfamily of zinc-metalloproteinases with binding sites for cells and other matrix components. Proc Natl Acad Sci U S A 1997;94:2374-2379.
11. Fernandes RJ, Hirohata S, Engle JM, Colige A, Cohn DH, Eyre DR, et al. Procollagen II amino propeptide processing by ADAMTS-3. Insights on dermatosparaxis. J Biol Chem 2001;276:31502-31509.
12. Colige A, Vandenberghe I, Thiry M, Lambert CA, Van Beeumen J, Li SW, et al. Cloning and characterization of ADAMTS-14, a novel ADAMTS displaying high homology with ADAMTS-2 and ADAMTS-3. J Biol Chem 2002;277:5756-5766.
13. Lapiere CM, Nusgens B. Polymerization of procollagen in vitro. Biochim Biophys Acta 1974;342:237-246.
14. Hulmes DJ, Kadler KE, Mould AP, Hojima Y, Holmes DF, Cummings C, et al. Pleomorphism in type I collagen fibrils produced by persistence of the procollagen N-propeptide. J Mol Biol 1989;210:337-345.
15. Pierard GE, Le T, Hermanns JF, Nusgens BV, Lapiere CM. Morphometric study of cauliflower collagen fibrils in dermatosparaxis of the calves. Coll Relat Res 1987;6:481-492.
16. Nusgens BV, Verellen-Dumoulin C, Hermanns-Le T, De Paepe A, Nuytinck L, Pierard GE, et al. Evidence for a relationship between Ehlers-Danlos type VII C in humans and bovine dermatosparaxis. Nat Genet 1992;1:214-217.
17. Colige A, Sieron AL, Li SW, Schwarze U, Petty E, Wertelecki W, et al. Human Ehlers-Danlos syndrome type VII C and bovine dermatosparaxis are caused by mutations in the procollagen I N-proteinase gene. Am J Hum Genet 1999;65:308-317.
18. Colige A, Nuytinck L, Hausser I, van Essen AJ, Thiry M, Herens C, et al. Novel types of mutation responsible for the dermatosparactic type of Ehlers-Danlos syndrome (type VIIC) and common polymorphisms in the ADAMTS2 gene. J Invest Dermatol 2004;123:656-663.
19. Tuderman L, Kivirikko KI, Prockop DJ. Partial purification and characterization of a neutral protease which cleaves the N-terminal propeptides from procollagen. Biochemistry (Mosc) 1978;17:2948-2954.
20. Wang WM, Lee S, Steiglitz BM, Scott IC, Lebares CC, Allen ML, et al. Transforming growth factor-beta induces secretion of activated ADAMTS-2. A procollagen III N-proteinase. J Biol Chem 2003;278:19549-19557.
21. Colige A, Ruggiero F, Vandenberghe I, Dubail J, Kesteloot F, Van Beeumen J, et al. Domains and maturation processes that regulate the activity of ADAMTS-2, a metalloproteinase cleaving the aminopropeptide of fibrillar procollagens types I-III and V. J Biol Chem 2005;280:34397-34408.
22. Li SW, Arita M, Fertala A, Bao Y, Kopen GC, Langsjo TK, et al. Transgenic mice with inactive alleles for procollagen N-proteinase (ADAMTS-2) develop fragile skin and male sterility. Biochem J 2001;355:271-278.
23. Ezure T, Sakamoto T, Tsuji H, Lunz JG III, Murase N, Fung JJ, et al. The development and compensation of biliary cirrhosis in interleukin-6-deficient mice. Am J Pathol 2000;156:1627-1639.
24. Bergman I, Loxley R. Two improved and simplified methods for the spectrophotometric determination of hydroxyproline. Anal Chem 1963;35:1961-1965.
25. Waldrop FS, Puchtler H. Light microscopic distinction of collagens in hepatic cirrhosis. Histochemistry 1982;74:487-491.
26. Laemmli UK. Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature 1970;227:680-685.
27. Towbin H, Staehelin T, Gordon J. Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: procedure and some applications. Proc Natl Acad Sci U S A 1979;76:4350-4354.
28. Paye M, Etievant C, Michiels F, Pierard D, Nusgens B, Lapiere CM. Characterization of a spontaneously transformed pulmonary embryonic rat (PER) epithelial cell line. J Cell Sci 1986;86:83-93.
29. Lambert CA, Colige AC, Lapiere CM, Nusgens BV. Coordinated regulation of procollagens I and III and their post-translational enzymes by dissipation of mechanical tension in human dermal fibroblasts. Eur J Cell Biol 2001;80:479-485.
30. Lambert CA, Colige AC, Munaut C, Lapiere CM, Nusgens BV. Distinct pathways in the over-expression of matrix metalloproteinases in human fibroblasts by relaxation of mechanical tension. Matrix Biol 2001;20:397-408.
31. Nakamura K, Nonaka H, Saito H, Tanaka M, Miyajima A. Hepatocyte proliferation and tissue remodeling is impaired after liver injury in oncostatin M receptor knockout mice. HEPATOLOGY 2004;39:635-644.
32. Colige A, Beschin A, Samyn B, Goebels Y, Van Beeumen J, Nusgens BV, et al. Characterization and partial amino acid sequencing of a 107-kDa procollagen I N-proteinase purified by affinity chromatography on immobilized type XIV collagen. J Biol Chem 1995;270:16724-16730.
33. Le Goff C, Somerville RP, Kesteloot F, Powell K, Birk DE, Colige AC, et al. Regulation of procollagen amino-propeptide processing during mouse embryogenesis by specialization of homologous ADAMTS proteases: insights on collagen biosynthesis and dermatosparaxis. Development 2006;133:1587-1596.
34. Hemmann S, Graf J, Roderfeld M, Roeb E. Expression of MMPs and TIMPs in liver fibrosis - a systematic review with special emphasis on anti-fibrotic strategies. J Hepatol 2007;46:955-975.
35. Yata Y, Takahara T, Furui K, Zhang LP, Watanabe A. Expression of matrix metalloproteinase-13 and tissue inhibitor of metalloproteinase-1 in acute liver injury. J Hepatol 1999;30:419-424.
36. Mohammed FF, Smookler DS, Taylor SE, Fingleton B, Kassiri Z, Sanchez OH, et al. Abnormal TNF activity in Timp3-/- mice leads to chronic hepatic inflammation and failure of liver regeneration. Nat Genet 2004;36:969-977.
37. Issa R, Zhou X, Trim N, Millward-Sadler H, Krane S, Benyon C, et al. Mutation in collagen-1 that confers resistance to the action of collagenase results in failure of recovery from CCl4-induced liver fibrosis, persistence of activated hepatic stellate cells, and diminished hepatocyte regeneration. FASEB J 2003:17:47-49.
38. Xia JL, Dai C, Michalopoulos GK, Liu Y. Hepatocyte growth factor attenuates liver fibrosis induced by bile duct ligation. Am J Pathol 2006;168:1500-1512.
39. Wang WM, Ge G, Lim NH, Nagase H, Greenspan DS. TIMP-3 inhibits the procollagen N-proteinase ADAMTS-2. Biochem J 2006;398:515-519.
40. Bickel M, Baringhaus KH, Gerl M, Gunzler V, Kama J, Schmidts L, et al. Selective inhibition of hepatic collagen accumulation in experimental liver fibrosis in rats by a new prolyl 4-hydroxylase inhibitor. HEPATOLOGY 1998;28:404-411.
41. Sakaida I, Uchida K, Hironaka K, Okita K. Prolyl 4-hydroxylase inhibitor (HOE 077) prevents TIMP-1 gene expression in rat liver fibrosis. J Gastroenterol 1999:34:376-377.