Alcohol dehydrogenase III exacerbates liver fibrosis by enhancing stellate cell activation and suppressing natural killer cells in mice

Hepatology

Volumn 60, Issue 3, 2014, Pages 1044-1053

  Yi, Hyon Seung ^a   Lee, Young Sun ^a   Byun, Jin Seok ^b   Seo, Wonhyo ^a   Jeong, Jong Min ^a   Park, Ogyi ^c   Duester, Gregg ^d   Haseba, Takeshi ^e   Kim, Sun Chang ^a,f   Park, Keun Gyu ^g   Gao, Bin ^c   Jeong, Won Il ^a  

^a Korea Advanced Institute of Science and Technology (KAIST)   (South Korea)

^b Kyungpook National University   (South Korea)

^c NATIONAL INSTITUTE ON ALCOHOL ABUSE AND ALCOHOLISM   (United States)

^d BURNHAM INSTITUTE   (United States)

^e NIPPON MEDICAL SCHOOL   (Japan)

^f Intelligent Synthetic Biology Center   (South Korea)

^g Kyungpook National University School of Medicine   (South Korea)

Author keywords

[No Author keywords available]

Indexed keywords

4 METHYLPYRAZOLE; ALCOHOL DEHYDROGENASE; ALCOHOL DEHYDROGENASE III; ALPHA SMOOTH MUSCLE ACTIN; GAMMA INTERFERON; INTERLEUKIN 6; MONOCYTE CHEMOTACTIC PROTEIN 1; RETINOL; TRANSFORMING GROWTH FACTOR BETA1; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; APOPTOSIS; ARTICLE; BILE DUCT LIGATION; BONE MARROW TRANSPLANTATION; CARBON TETRACHLORIDE-INDUCED LIVER FIBROSIS; CELL ACTIVATION; CELL PROLIFERATION; CONTROLLED STUDY; DISEASE EXACERBATION; DOWN REGULATION; ENZYME INHIBITION; ENZYME METABOLISM; GENE EXPRESSION; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; MALE; MOUSE; NATURAL KILLER CELL; NONHUMAN; PANCREATIC STELLATE CELL; PRIORITY JOURNAL; PROTEIN DEPLETION; REAL TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION;

ALDEHYDE OXIDOREDUCTASES; ANIMALS; BONE MARROW TRANSPLANTATION; HEPATIC STELLATE CELLS; INTERFERON-GAMMA; KILLER CELLS, NATURAL; LIVER CIRRHOSIS; MALE; MICE; MICE, INBRED C57BL;

EID: 84906498641     PISSN: 02709139     EISSN: 15273350     Source Type: Journal    
DOI: 10.1002/hep.27137     Document Type: Article

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