CXCL12 induces hepatic stellate cell contraction through a calcium-independent pathway

American Journal of Physiology - Gastrointestinal and Liver Physiology

Volumn 305, Issue 5, 2013, Pages

  Saiman, Yedidya ^a   Agarwal, Ritu ^a   Hickman, DaShawn A ^b   Fausther, Michel ^b   El Shamy, Ahmed ^a,c   Dranoff, Jonathan A ^b   Friedman, Scott L ^a   Bansal, Meena B ^a  

^a MOUNT SINAI SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF ARKANSAS FOR MEDICAL SCIENCES   (United States)

^c SUEZ CANAL UNIVERSITY   (Egypt)

Author keywords

CXCR4; Liver fibrosis; Portal hypertension

Indexed keywords

4 (1 AMINOETHYL) N (4 PYRIDYL)CYCLOHEXANECARBOXAMIDE; ALPHA SMOOTH MUSCLE ACTIN; BETA TUBULIN; CALCIUM; CHEMOKINE RECEPTOR CXCR4; ETHYLENE GLYCOL 1,2 BIS(2 AMINOPHENYL) ETHER N,N,N',N' TETRAACETIC ACID; MYOSIN LIGHT CHAIN; PLERIXAFOR; RHO KINASE; STROMAL CELL DERIVED FACTOR 1;

ANIMAL CELL; ARTICLE; CAPILLARY RESISTANCE; CELL ACTIVATION; CHRONIC LIVER DISEASE; CONTROLLED STUDY; HUMAN; HUMAN CELL; LIVER BLOOD FLOW; LIVER FIBROSIS; NONHUMAN; PERICYTE; PORTAL HYPERTENSION; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; REGULATORY MECHANISM; STELLATE CELL;

CXCR4; LIVER FIBROSIS; PORTAL HYPERTENSION;

ACTINS; ANIMALS; CALCIUM; CELL LINE; CELL SHAPE; CHELATING AGENTS; CHEMOKINE CXCL12; COLLAGEN; DOSE-RESPONSE RELATIONSHIP, DRUG; GELS; HEPATIC STELLATE CELLS; HUMANS; MICE; MYOSIN LIGHT CHAINS; PHENOTYPE; PHOSPHORYLATION; PROTEIN KINASE INHIBITORS; RECEPTORS, CXCR4; RECOMBINANT PROTEINS; RHO-ASSOCIATED KINASES; RNA INTERFERENCE; SIGNAL TRANSDUCTION; TRANSFECTION;

EID: 84883334111     PISSN: 01931857     EISSN: 15221547     Source Type: Journal    
DOI: 10.1152/ajpgi.00185.2012     Document Type: Article

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