A high-cholesterol diet exacerbates liver fibrosis in mice via accumulation of free cholesterol in hepatic stellate cells

Gastroenterology

Volumn 142, Issue 1, 2012, Pages

  Teratani, Toshiaki ^a   Tomita, Kengo ^a,b   Suzuki, Takahiro ^a   Oshikawa, Tetsuya ^a   Yokoyama, Hirokazu ^a   Shimamura, Katsuyoshi ^a   Tominaga, Susumu ^b   Hiroi, Sadayuki ^b   Irie, Rie ^c   Okada, Yoshikiyo ^b   Kurihara, Chie ^b   Ebinuma, Hirotoshi ^a   Saito, Hidetsugu ^d   Hokari, Ryota ^b   Sugiyama, Kazuo ^a   Kanai, Takanori ^a   Miura, Soichiro ^b   Hibi, Toshifumi ^a  

^a KEIO UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^b NATIONAL DEFENSE MEDICAL COLLEGE   (Japan)

^c KAWASAKI MUNICIPAL HOSPITAL   (Japan)

^d KEIO UNIVERSITY   (Japan)

Author keywords

Dyslipidemia; Lipopolysaccharide; Liver Disease; Mouse Model

Indexed keywords

ACTIVIN; ALPHA SMOOTH MUSCLE ACTIN; BONE MORPHOGENETIC PROTEIN; CARBON TETRACHLORIDE; CHOLESTEROL; CORN OIL; GLUCOSE; TOLL LIKE RECEPTOR 4; TRANSFORMING GROWTH FACTOR BETA; TRIACYLGLYCEROL;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; BILE DUCT LIGATION; CELL ACTIVATION; CELL CULTURE; CELL ISOLATION; CHOLESTEROL BLOOD LEVEL; CHOLESTEROL DIET; CONTROLLED STUDY; DISEASE COURSE; DISEASE EXACERBATION; DOWN REGULATION; FIBROGENESIS; GLUCOSE BLOOD LEVEL; HEPATITIS; IMMUNOHISTOCHEMISTRY; KUPFFER CELL; LIVER CELL; LIVER CELL DAMAGE; LIVER FIBROSIS; MALE; MOUSE; NIEMANN PICK DISEASE; NONHUMAN; PRIORITY JOURNAL; RAT; SENSITIZATION; STELLATE CELL; TRIACYLGLYCEROL BLOOD LEVEL;

EID: 83755163159     PISSN: 00165085     EISSN: 15280012     Source Type: Journal    
DOI: 10.1053/j.gastro.2011.09.049     Document Type: Article

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