Flavonoid interactions during digestion, absorption, distribution and metabolism: A sequential structure-activity/property relationship-based approach in the study of bioavailability and bioactivity

Drug Metabolism Reviews

Volumn 47, Issue 2, 2015, Pages 175-190

  Gonzales, Gerard Bryan ^a   Smagghe, Guy ^a   Grootaert, Charlotte ^a   Zotti, Moises ^a,b   Raes, Katleen ^a   Camp, John Van ^a  

^a GHENT UNIVERSITY   (Belgium)

^b FEDERAL UNIVERSITY OF SANTA MARIA   (Brazil)

Author keywords

ABC transporters; Amylase; Flavonoids; Glucuronidation; Lipase; Mucus layer; Protein flavonoid interaction; QSAR; Sulfation

Indexed keywords

ABC TRANSPORTER; BREAST CANCER RESISTANCE PROTEIN; FLAVONOID; MULTIDRUG RESISTANCE PROTEIN; PROTEINASE;

DIGESTION; DRUG ABSORPTION; DRUG ACTIVITY; DRUG BIOAVAILABILITY; DRUG DISTRIBUTION; DRUG GLUCURONIDATION; DRUG METABOLISM; DRUG PROTEIN BINDING; FAT INTAKE; FOOD; FOOD DRUG INTERACTION; HUMAN; INTESTINE MUCOSA PERMEABILITY; REVIEW; STRUCTURE ACTIVITY RELATION; UPPER GASTROINTESTINAL TRACT; BIOAVAILABILITY; BIOTRANSFORMATION; CHEMICAL STRUCTURE; CHEMISTRY; GASTROINTESTINAL ABSORPTION; GASTROINTESTINAL TRACT; HYDROXYLATION; METABOLISM; PHYSIOLOGY; TISSUE DISTRIBUTION;

BIOLOGICAL AVAILABILITY; BIOTRANSFORMATION; DIGESTION; FLAVONOIDS; FOOD-DRUG INTERACTIONS; GASTROINTESTINAL ABSORPTION; GASTROINTESTINAL TRACT; HUMANS; HYDROXYLATION; MOLECULAR STRUCTURE; STRUCTURE-ACTIVITY RELATIONSHIP; TISSUE DISTRIBUTION;

EID: 84932165702     PISSN: 03602532     EISSN: 10979883     Source Type: Journal    
DOI: 10.3109/03602532.2014.1003649     Document Type: Review

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