Prenyl-flavonoids as potent inhibitors of the Pdr5p multidrug ABC transporter from Saccharomyces cerevisiae

Biochemistry

Volumn 39, Issue 23, 2000, Pages 6910-6917

  Conseil, Gwenaëlle ^a   Decottignies, Anabelle ^b,c   Jault, Jean Michel ^a   Comte, Gilles ^d   Barron, Denis ^d   Goffeau, André ^b   Di Pietro, Attilio ^a  

^a INSTITUT DE BIOLOGIE ET CHIMIE DES PROTÉINES   (France)

^b UNIVERSITÉ CATHOLIQUE DE LOUVAIN   (Belgium)

^c UNIVERSITÉ LYON 1   (France)

^d IMPERIAL CANCER RESEARCH FUND   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ABC TRANSPORTER; FLAVONOID; FUNGAL PROTEIN; GLYCOPROTEIN P;

ARTICLE; BINDING AFFINITY; CHEMICAL STRUCTURE; GENE MUTATION; NONHUMAN; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN EXPRESSION; SACCHAROMYCES CEREVISIAE;

ADENOSINE TRIPHOSPHATASES; ADENOSINE TRIPHOSPHATE; ATP-BINDING CASSETTE TRANSPORTERS; DNA-BINDING PROTEINS; ENZYME INHIBITORS; FLAVONOIDS; FUNGAL PROTEINS; KINETICS; MAGNESIUM; MEMBRANE PROTEINS; MOLECULAR STRUCTURE; PROTEIN BINDING; PYROPHOSPHATASES; RHODAMINES; SACCHAROMYCES CEREVISIAE; SACCHAROMYCES CEREVISIAE PROTEINS; SPECTROMETRY, FLUORESCENCE; SUBSTRATE SPECIFICITY; TRANS-ACTIVATORS; TRYPTOPHAN;

PROTOZOA; SACCHAROMYCES CEREVISIAE;

EID: 0034643830     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi000040f     Document Type: Article

References (39)

1. Di Pietro, A., Godinot, C., Bouillant, M.-L., and Gautheron, D. C. (1975) Biochimie 57, 959-967.
2. Zyma, V. L., Miroshnichenko, N. S., Danilova, V. M., and En Gin, E. (1988) Gen. Physiol. Biophys. 7, 165-175.
3. Hirano, T., Oka, K., and Akiba, M. (1989) Life Sci. 45, 1111-1117.
4. Thiyagarajah, P., Kuttan, S. C., Lim, S. C., Teo, T. S., and Das, N. P. (1991) Biochem. Pharmacol. 41, 669-675.
5. Jinsart, W., Ternai, B., and Polya, G. M. (1992) Biol. Chem. Hoppe-Seyler 373, 205-211.
6. Ferriola, P. C., Cody, V., and Middleton, E., Jr. (1989) Biochem. Pharmacol. 38, 1617-1624.
7. Hagiwara, M., Inoue, S., Tanaka, T., Nunoki, K., Ito, M., and Hidaka, H. (1988) Biochem. Pharmacol. 37, 2987-2992.
8. Akiyama, T., Ishida, J., Nakagawa, S., Ogawara, H., Watanabe, S., Itoh, N., Shibuya, M., and Fukami, Y. (1987) J. Biol. Chem. 262, 5592-5595.
9. Robinson, M. J., Corbett, A. H., and Osheroff, N. (1993) Biochemistry 32, 3638-3643.
10. De Azevedo, W. F., Jr., Mueller-Dieckmann, H.-J., Schulze-Gahmen, U., Worland, P. J., Sausville, E., and Kim, S.-H. (1996) Proc. Natl. Acad. Sci. U.S.A. 93, 2735-2740.
11. Sicheri, F., Moarefi, I., and Kuriyan, J. (1997) Nature 385, 602-609.
12. Critchfield, J. W., Welsh, C. J., Phang, J. M., and Yeh, G. C. (1994) Biochem. Pharmacol. 48, 1437-1445.
13. Scambia, G., Ranelletti, F. O., Benedetti Panici, P., De Vincenzo, R., Bonanno, G., Ferrandina, G., Piantelli, M., Bussa, S., Rumi, C., Cianfriglia, M., and Mancuso, S. (1994) Cancer Chemother. Pharmacol. 34, 459-464.
14. Conseil, G., Baubichon-Cortay, H., Dayan, G., Jault, J.-M., Barron, D., and Di Pietro, A. (1998) Proc. Natl. Acad. Sci. U.S.A. 95, 9831-9836.
15. Pérez-Victoria, J. M., Chiquero, M. J., Conseil, G., Dayan, G., Di Pietro, A., Barron, D., Castanys, S., and Gamarro, F. (1999) Biochemistry 38, 1736-1743.
16. Shapiro, A. B., and Ling, V. (1997) Biochem. Pharmacol. 53, 587-596.
17. Balzi, E., and Goffeau, A. (1995) J. Bioenerg. Biomembr. 27, 71-76.
18. Decottignies, A., and Goffeau, A. (1997) Nat. Genet. 15, 137-145.
19. Decottignies, A., Lambert, L., Catty, P., Degand, H., Epping, E. A., Moye-Rowley, W. S., Balzi, E., and Goffeau, A. (1995) J. Biol. Chem. 270, 18150-18157.
20. Decottignies, A., Grant, A. M., Nichols, J. W., de Wet, H., McIntosh, D., and Goffeau, A. (1998) J. Biol. Chem. 273, 12612-12622.
21. Decottignies, A., Kolaczkowski, M., Balzi, E., and Goffeau, A. (1994) J. Biol. Chem. 269, 12797-12803.
22. Balzi, E., Wang, M., Leterme, S., Van Dyck, L., and Goffeau, A. (1994) J. Biol. Chem. 269, 2206-2214.
23. Kolaczkowski, M., van der Rest, M., Cybularz-Kolaczkowska, A., Soumillon, J.-P., Konings, W. N., and Goffeau, A. (1996) J. Biol. Chem. 271, 31543-31548.
24. Dayan, G., Jault, J.-M., Baubichon-Cortay, H., Jault, J.-M., Cortay, J.-C., Deléage, G., and Di Pietro, A. (1996) J. Biol. Chem. 271, 11652-11658.
25. Dayan, G., Jault, J.-M., Baubichon-Cortay, H., Baggetto, L. G., Renoir, J. M., Baulieu, E. E., Gros, P., and Di Pietro, A. (1997) Biochemistry 36, 15208-15215.
26. Barron, D., El Aidi, C., and Mariotte, A.-M. (1994) Phytochem. Anal. 5, 309-314.
27. Lowry, O. H., Rosebrough, N. J., Farr, A. L., and Randall, R. J. (1951) J. Biol. Chem. 193, 265-275.
28. Fiske, C. H., and Subbarow, Y. J. (1925) J. Biol. Chem. 66, 375-400.
29. Baubichon-Cortay, H., Baggetto, L. G., Dayan, G., and Di Pietro, A. (1994) J. Biol. Chem. 269, 22983-22989.
30. Borgnia, M. J., Eytan, G. D., and Assaraf, Y. G. (1996) J. Biol. Chem. 271, 3163-3171.
31. Liu, R., and Sharom, F. J. (1996) Biochemistry 35, 11865-11873.
32. Shapiro, A. B., and Ling, V. (1997) Eur. J. Biochem. 250, 130-137.
33. Extra, J.-M., Rousseau, F., Bruno, R., Clavel, M., Le Bail, N., and Marty, M. (1993) Cancer Res. 53, 1037-1042.
34. Wils, P., Phung-Ba, V., Warnery, A., Lechardeur, D., Raeissi, S., Hidalgo, I. J., and Scherman, D. (1994) Biochem. Pharmacol. 48, 1528-1530.
35. Gruol, D. J., Zee, M. C., Trotter, J., and Bourgeois, S. (1994) Cancer Res. 54, 3088-3091.
36. Lecureur, V., Fardel, O., and Guillouzo, A. (1994) FEBS Lett. 355, 187-191.
37. Murakami, S., Muramatsu, M., and Tomisawa, K. (1999) J. Enzyme Inhib. 14, 151-166.
38. Dey, S., Ramachandra, M., Pastan, I., Gottesman, M. M., and Ambudkar, S. V. (1997) Proc. Natl. Acad. Sci. U.S.A. 94, 10594-10599.
39. Dufour, J.-P., and Goffeau, A. (1980) Eur. J. Biochem. 105, 145-154.