Isolation of a novel catechin from Bergenia rhizomes that has pronounced lipase-inhibiting and antioxidative properties

Fitoterapia

Volumn 82, Issue 2, 2011, Pages 212-218

  Ivanov, Sergey A ^a   Nomura, Kenzo ^b   Malfanov, Ilya L ^a   Sklyar, Ilya V ^a   Ptitsyn, Leonid R ^a  

^a Ajinomoto Genetika Research Institute   (Russian Federation)

^b Research Institute for Health Fundamentals   (Japan)

Author keywords

5 di O gallate; Antioxidants; Human pancreatic lipase (HPL); Inhibition

Indexed keywords

1,1 DIPHENYL 2 PICRYLHYDRAZYL; ALCOHOL; ANTIOXIDANT; CATECHIN 3 O GALLATE; CATECHIN 3,5 DI O GALLATE; ENZYME INHIBITOR; FREE RADICAL; TANNIN DERIVATIVE; TRIACYLGLYCEROL LIPASE; UNCLASSIFIED DRUG;

ANTIOXIDANT ACTIVITY; ARTICLE; BERGENIA CRASSIFOLIA; CARBON NUCLEAR MAGNETIC RESONANCE; CHROMATOGRAPHY; DRUG HYDROLYSIS; DRUG ISOLATION; DRUG STRUCTURE; ENZYME INHIBITION; HETERONUCLEAR MULTIPLE BOND CORRELATION; HETERONUCLEAR SINGLE QUANTUM COHERENCE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; IN VITRO STUDY; MASS SPECTROMETRY; MEDICINAL PLANT; NONHUMAN; PRIORITY JOURNAL; PROTON NUCLEAR MAGNETIC RESONANCE; RHIZOME;

BERGENIA;

EID: 79952363193     PISSN: 0367326X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.fitote.2010.09.013     Document Type: Article

References (37)

1. Foster-Schubert KE, Cummings DE. Emerging therapeutic strategies for obesity. Endocr Rev 2006;27:779-93. (Pubitemid 44936060)
2. Shi Y, Burn P. Lipid metabolic enzymes: emerging drug targets for the treatment of obesity. Nat Rev Drug Discov 2004;3:695-710. (Pubitemid 39173510)
3. Strader CD, Hwa JJ, Van Heek M, Parker EM. Novel molecular targets for the treatment of obesity. Drug Discov Today 1998;3:250-6. (Pubitemid 28255329)
4. MukherjeeM. Human digestive and metabolic lipases - a brief review. J Mol Catal B Enzym 2003;22:369-76. (Pubitemid 36802038)
5. Thomson ABR, De Pover A, Keelan M, Jarocka-Cyrta E, Clandinin MT. Inhibition of lipid absorption as an approach to the treatment of obesity. In: Rubin B, Dennis EA, editors. Methods in Enzymology. San Diego, CA: Academic Press; 1997. p. 3-41.
6. Birari RB, Bhutani KK. Pancreatic lipase inhibitors from natural sources: unexplored potential. Drug Discov Today 2007;12(19/20):879-89. (Pubitemid 47539967)
7. Steinberg D, Parthasarathy S, Carew TE, Khoo JC, Witztum JL. Beyond cholesterol. Modifications of low density lipoprotein that increase its atherogenicity. N Engl J Med 1989;320:915-24. (Pubitemid 19101597)
8. Byers T. Vitamin E supplements and coronary heart disease. Nutr Rev 1993;51:333-45.
9. BosMA, Vennat B,MeunierMT, PougetMP, Pourrat A, Fialip J. Procyanidins fromtormentil antioxidant properties towards lipoperoxidation and antielastase activity. Biol Pharm Bull 1996;19(1):146-8. (Pubitemid 26057404)
10. Vennat B, Bos MA, Pourrat A, Bastide P. Procyanidins from tormentil fractionation and study of the anti-radical activity towards superoxide anion. Biol Pharm Bull 1994;17(12):1613-5.
11. Vereschagin VI, Sobolevskaya KA, Yakubova AI. Useful plants of the western Siberia. Moscow-Leningrad: Publishing of Academy of Sciences of the USSR; 1959. p. 15-6.
12. Gammerman AF, Grom II. Wild growing medicinal plants of USSR, Medicine, Moscow; 1976.
13. Fedoseyeva LM, Kerasheva SI, Karabasova EV. Antimicrobial activity of dry extract from leaves of Bergenia crassifolia (L.) Fritsch. with respect to pathogens of some suppurative inflammatory diseases. Rastitel'nye Resursy (Russ) 2000;36:153-7.
14. Shilova IV, Pisareva SI, Krasnov EA, Bruzhev MA, Pyak AI. Antioxidant properties of Bergenia crassifolia extract. Pharm Chem J 2006;40:39-42.
15. Pozharitskaya ON, Ivanova SA, Shikov AN, Makarov VG, Galambosi B. Separation and evaluation of free radical-scavenging activity of phenol components of green, brown, and black leaves of Bergenia crassifolia by using HPTLC-DPPH method. J Sep Sci 2007;30:2447-51. (Pubitemid 350020043)
16. Churin AA, Masnaia NV, Sherstoboev EY, Suslov NI. Effect of Bergenia crassifolia extract on specific immune response parameters under extremal conditions. Eksp Klin Farmakol (Russ) 2005;68:51-4. (Pubitemid 41564987)
17. Kokoska L, Polezny Z, Rada V, Nepovim A, Vanek T. Screening of some Siberian medicinal plants for antimicrobial activity. J Ethnopharmacol 2002;82:51-3.
18. Briukhanov VM, Fedoseeva LM. The effect of preparations made from badan leaves on kidney function in an experiment. Eksp Klin Farmakol (Russ) 1993;56(1):39-41.
19. Popov SV, Popova GY, Nikolaeva SY, Golovchenko VV, Ovodova RG. Immunostimulating activity of pectic polysaccharide from Bergenia crassifolia (L) Fritsch. Phytother Res 2005;19:1052-6. (Pubitemid 43133464)
20. Nazir N, Koul S, Qurishi MA, Taneja SC, Ahmad SF, Bani S, Qazi GN. Immunomodulatory effect of bergenin and norbergenin against adjuvant-induced arthritis - a flow cytometric study. J Ethnopharmacol 2007;112:401-5. (Pubitemid 46778958)
21. Kunkel G. Plants for human consumption. Koenigatein: Koeltz Scientific Books; 1984.
22. Panossian A, Wikman G. Effect of adaptogens on the central nervous system. Arquivos Brasileiros de Fitomedicina Científica 2005;3:29-51.
23. Haslam E. (+)-Catechin-3-gallate and a polymeric proanthocyanidin from Bergenia species. J Chem Soc C 1969;14:1824-8.
24. Pop C, Vlase L, Tamas M. Natural resources containing arbutin. Determination of arbutin in the leaves of Bergenia crassifolia (L.) Fritsch. acclimated in Romania. Not Bot Hort Agrobot Cluj 2009;37(1):129-32.
25. Bohm BA, Donevan LS, Bhat UG. Flavonoids of some species of Bergenia Francoa Parnassia and Lepuropetalon. Biochem Syst Ecol 1986;14:75-7.
26. Shikov AN, Pozharitskaya ON, Makarova MN, Dorman HJD, Makarov VG, Hiltunen R, Galambosi B. Adaptogenic effect of black and fermented leaves of Bergenia crassifolia L. in mice. J Funct Foods 2010;2(1):71-6.
27. Hsu C-Y. Antioxidant activity of extract from Polygonum aviculare L. Biol Res 2006;39:281-8.
28. Nakagawa K, Ninomiya M, Okubo T, Aoi N, Juneja LR, Kim M, Yamanaka K, Miyazawa T. Tea catechin supplementation increases antioxidant capacity and prevents phospholipid hydroperoxidation in plasma of humans. J Agric Food Chem 1999;47(10):3967-73. (Pubitemid 29506185)
29. Kaponen M, Ossipov V, Sinkkonen J, et al. Quantitative analysis of polymeric proanthocyanidines in birch leaves with normal-phase HPLC. Phytochem Anal 2006;17:149-56.
30. Ohnishi-Kameyama M, Yanagida A, Kanda T, Nagata T. Identification of catechin oligomers from apple (Malus pumila cv.Fuji) in matrix-assisted laser desorption/ionization time-of-flight mass spectrometry and fastatom bombardment mass spectrometry. Rapid Commun Mass Spectrom 1997;11:31-6. (Pubitemid 27102892)
31. Hyoung JK, Lee JY, Kim SM, et al. A new epicatechin gallate and calpain inhibitory activity from Orostachys japonica. Fitoterapia 2009;80:73-6.
32. Davis AL, Cai Y, Davies AP, Lewie JR. 1H and 13C NMR assignments of some green tea polyphenols. Magn Reson Chem 1996;34:887-90.
33. Saijyo J, Suzuki Y, Okuno Y, et al. α-Glucosidase inhibitor from Bergenia ligulata. J Oleo Sci 2008;57(8):431-5.
34. Daniel R, Wagner V, et al. Determination of catechin diastereomers from the leaves of Byrsonima species using chiral HPLC-PAD-CD. Chirality 2010;22(8):726-33.
35. Nakai M, Fukui Y, Asami S, et al. Inhibitory effects of oolong tea polyphenols on pancreatic lipase in vitro. J Agric Food Chem 2005;53: 4593-8. (Pubitemid 40855493)
36. Cho EJ, Yokozawa T, Rhyu DY, Kim SC, Shibahara N, Park JC. Study on the inhibitory effects of Korean medicinal plants and their main compounds on the 1, 1-diphenyl-2-picrylhydrazyl radical. Phytomedicine 2003;10 (6-7):544-51. (Pubitemid 37092680)
37. Mun'im A, Negishi O, Ozawa T. Antioxidative compounds from Crotalaria sessiliflora. Biosci Biotechnol Biochem 2003;67(2):410-4. (Pubitemid 39252002)