-
1
-
-
0037235949
-
Engineered antibodies
-
Hudson PJ, Souriau C. Engineered antibodies. Nat Med 2003;9:129-134.
-
(2003)
Nat Med
, vol.9
, pp. 129-134
-
-
Hudson, P.J.1
Souriau, C.2
-
3
-
-
84859386987
-
Intracellular tumor-associated antigens represent effective targets for passive immunotherapy
-
Noguchi T, Kato T, Wang L. Intracellular tumor-associated antigens represent effective targets for passive immunotherapy. Cancer Res 2012;72:1672-1682.
-
(2012)
Cancer Res
, vol.72
, pp. 1672-1682
-
-
Noguchi, T.1
Kato, T.2
Wang, L.3
-
4
-
-
0037068363
-
Production and characterisation of a recombinant scFv reactive with human gastrointestinal carcinomas
-
Kim DJ, Chung JH, Ryu YS. Production and characterisation of a recombinant scFv reactive with human gastrointestinal carcinomas. Br J Cancer 2002;87:405-413.
-
(2002)
Br J Cancer
, vol.87
, pp. 405-413
-
-
Kim, D.J.1
Chung, J.H.2
Ryu, Y.S.3
-
5
-
-
0036222797
-
Pharmacokinetics of rhuMAb CD18, a recombinant humanised monoclonal antibody fragment to CD18, in normal healthy human volunteers
-
Allison DE, Gourlay SG, Koren E, et al. Pharmacokinetics of rhuMAb CD18, a recombinant humanised monoclonal antibody fragment to CD18, in normal healthy human volunteers. BioDrugs 2002;16:63-70.
-
(2002)
BioDrugs
, vol.16
, pp. 63-70
-
-
Allison, D.E.1
Gourlay, S.G.2
Koren, E.3
-
7
-
-
77649291920
-
Improved cancer therapy and molecular imaging with multivalent, multispecific antibodies
-
Sharkey RM, Rossi EA, Chang CH, Goldenberg DM. Improved cancer therapy and molecular imaging with multivalent, multispecific antibodies. Cancer Biother Radiopharm 2010;25:1-12.
-
(2010)
Cancer Biother Radiopharm
, vol.25
, pp. 1-12
-
-
Sharkey, R.M.1
Rossi, E.A.2
Chang, C.H.3
Goldenberg, D.M.4
-
8
-
-
77951132888
-
Expression and purification of an anti-clenbuterol single chain Fv antibody in Escherichia coli
-
Wang H, Liu X, He Y. Expression and purification of an anti-clenbuterol single chain Fv antibody in Escherichia coli. Protein Expr Purif 2010;72:26-31.
-
(2010)
Protein Expr Purif
, vol.72
, pp. 26-31
-
-
Wang, H.1
Liu, X.2
He, Y.3
-
9
-
-
84860659599
-
Expression of a single-chain variable-fragment antibody against a Fusarium virguliforme toxin peptide enhances tolerance to sudden death syndrome in transgenic soybean plants
-
Brar HK, Bhattacharyya MK. Expression of a single-chain variable-fragment antibody against a Fusarium virguliforme toxin peptide enhances tolerance to sudden death syndrome in transgenic soybean plants. Mol Plant Microbe Interact 2012;25:817-824.
-
(2012)
Mol Plant Microbe Interact
, vol.25
, pp. 817-824
-
-
Brar, H.K.1
Bhattacharyya, M.K.2
-
10
-
-
33845521492
-
A yeast platform for the production of single-chain antibody-green fluorescent protein fusions
-
Huang D, Shusta EV. A yeast platform for the production of single-chain antibody-green fluorescent protein fusions. Appl Environ Microbiol 2006;72:7748-7759.
-
(2006)
Appl Environ Microbiol
, vol.72
, pp. 7748-7759
-
-
Huang, D.1
Shusta, E.V.2
-
11
-
-
84864137357
-
Recombinant antibodies and in vitro selection technologies
-
Geyer CR, McCafferty J, Dubel S, et al. Recombinant antibodies and in vitro selection technologies. Methods Mol Biol 2012;901:11-32.
-
(2012)
Methods Mol Biol
, vol.901
, pp. 11-32
-
-
Geyer, C.R.1
McCafferty, J.2
Dubel, S.3
-
12
-
-
2442442119
-
Directed in vitro evolution and crystallographic analysis of a peptide-binding single chain antibody fragment (scFv) with low picomolar affinity
-
Zahnd C, Spinelli S, Luginbuhl B. Directed in vitro evolution and crystallographic analysis of a peptide-binding single chain antibody fragment (scFv) with low picomolar affinity. J Biol Chem 2004;279:18870-18877.
-
(2004)
J Biol Chem
, vol.279
, pp. 18870-18877
-
-
Zahnd, C.1
Spinelli, S.2
Luginbuhl, B.3
-
13
-
-
0034718615
-
Directed evolution of antibody fragments with monovalent femtomolar antigen-binding affinity
-
Boder ET, Midelfort KS, Wittrup KD. Directed evolution of antibody fragments with monovalent femtomolar antigen-binding affinity. Proc Natl Acad Sci USA 2000;97:10701-10705.
-
(2000)
Proc Natl Acad Sci USA
, vol.97
, pp. 10701-10705
-
-
Boder, E.T.1
Midelfort, K.S.2
Wittrup, K.D.3
-
15
-
-
0026699293
-
Selection of phage antibodies by binding affinity. Mimicking affinity maturation
-
Hawkins RE, Russell SJ, Winter G. Selection of phage antibodies by binding affinity. Mimicking affinity maturation. J Mol Biol 1992;226:889-896.
-
(1992)
J Mol Biol
, vol.226
, pp. 889-896
-
-
Hawkins, R.E.1
Russell, S.J.2
Winter, G.3
-
16
-
-
0030974119
-
In vitro selection and evolution of functional proteins by using ribosome display
-
Hanes J, Pluckthun A. In vitro selection and evolution of functional proteins by using ribosome display. Proc Natl Acad Sci USA 1997;94:4937-4942.
-
(1997)
Proc Natl Acad Sci USA
, vol.94
, pp. 4937-4942
-
-
Hanes, J.1
Pluckthun, A.2
-
17
-
-
0031574037
-
Antibody-ribosome-mRNA (ARM) complexes as efficient selection particles for in vitro display and evolution of antibody combining sites
-
He M, Taussig MJ. Antibody-ribosome-mRNA (ARM) complexes as efficient selection particles for in vitro display and evolution of antibody combining sites. Nucleic Acids Res 1997;25:5132-5134.
-
(1997)
Nucleic Acids Res
, vol.25
, pp. 5132-5134
-
-
He, M.1
Taussig, M.J.2
-
18
-
-
34248598174
-
Selection of single chain fragments against the phytopathogen Xanthomonas axonopodis pv. citri by ribosome display
-
Yuan Q, Xia Y, Nian S, et al. Selection of single chain fragments against the phytopathogen Xanthomonas axonopodis pv. citri by ribosome display. Enzyme Microbial Technol 2007;41:383-389.
-
(2007)
Enzyme Microbial Technol
, vol.41
, pp. 383-389
-
-
Yuan, Q.1
Xia, Y.2
Nian, S.3
-
20
-
-
0035598783
-
Analytical and preparative methods for purification of antibodies. Methods for purification of antibodies
-
Josi D, Lim Y-P. Analytical and preparative methods for purification of antibodies. Methods for purification of antibodies. Food Technol Biotechnol 2001;39:215-226.
-
(2001)
Food Technol Biotechnol
, vol.39
, pp. 215-226
-
-
Josi, D.1
Lim, Y.-P.2
-
21
-
-
35348880944
-
Four primordial immunoglobulin light chain isotypes, including lambda and kappa, identified in the most primitive living jawed vertebrates
-
Criscitiello MF, Flajnik MF. Four primordial immunoglobulin light chain isotypes, including lambda and kappa, identified in the most primitive living jawed vertebrates. Eur J Immunol 2007;37:2683-2694.
-
(2007)
Eur J Immunol
, vol.37
, pp. 2683-2694
-
-
Criscitiello, M.F.1
Flajnik, M.F.2
-
22
-
-
84874213990
-
Natural and man-made V-gene repertoires for antibody discovery
-
Finlay WJ, Almagro JC. Natural and man-made V-gene repertoires for antibody discovery. Front Immunol 2012;3:342. doi: 10.3389/fimmu.2012.00342.
-
(2012)
Front Immunol
, vol.3
, pp. 342
-
-
Finlay, W.J.1
Almagro, J.C.2
-
23
-
-
0022020969
-
Nucleotide sequences of five anti-lysozyme monoclonal antibodies
-
Darsley MJ, Rees AR. Nucleotide sequences of five anti-lysozyme monoclonal antibodies. EMBO J 1985;4:393-398.
-
(1985)
EMBO J
, vol.4
, pp. 393-398
-
-
Darsley, M.J.1
Rees, A.R.2
-
24
-
-
84877724826
-
Structural insights into the evolution of the adaptive immune system
-
Deng L, Luo M, Velikovsky A, Mariuzza RA. Structural insights into the evolution of the adaptive immune system. Annu Rev Biophys 2013;42:191-215.
-
(2013)
Annu Rev Biophys
, vol.42
, pp. 191-215
-
-
Deng, L.1
Luo, M.2
Velikovsky, A.3
Mariuzza, R.A.4
-
25
-
-
77951888124
-
Nanotechnology applications in surgical oncology
-
Singhal S, Nie S, Wang MD. Nanotechnology applications in surgical oncology. Annu Rev Med 2010;61:359-373.
-
(2010)
Annu Rev Med
, vol.61
, pp. 359-373
-
-
Singhal, S.1
Nie, S.2
Wang, M.D.3
-
26
-
-
18644361957
-
Antiferritin VL homodimer binds human spleen ferritin with high specificity
-
Nymalm Y, Kravchuk Z, Salminen T. Antiferritin VL homodimer binds human spleen ferritin with high specificity. J Struct Biol 2002;138:171-186.
-
(2002)
J Struct Biol
, vol.138
, pp. 171-186
-
-
Nymalm, Y.1
Kravchuk, Z.2
Salminen, T.3
-
27
-
-
39549094014
-
Characterization of the 4D5Flu single-chain antibody with a stimulus-responsive elastin-like peptide linker: A potential reporter of peptide linker conformation
-
Blenner MA, Banta S. Characterization of the 4D5Flu single-chain antibody with a stimulus-responsive elastin-like peptide linker: a potential reporter of peptide linker conformation. Protein Sci 2008;17:527-536.
-
(2008)
Protein Sci
, vol.17
, pp. 527-536
-
-
Blenner, M.A.1
Banta, S.2
-
28
-
-
0242384230
-
Design and assembly of anti-CD16 ScFv antibody with two different linker peptides
-
Feng J, Xie Z, Guo N, Shen B. Design and assembly of anti-CD16 ScFv antibody with two different linker peptides. J Immunol Methods 2003;282:33-43.
-
(2003)
J Immunol Methods
, vol.282
, pp. 33-43
-
-
Feng, J.1
Xie, Z.2
Guo, N.3
Shen, B.4
-
29
-
-
84863005606
-
Towards a universal disulphide stabilised single chain Fv format: Importance of interchain disulphide bond location and vL-vH orientation
-
Weatherill EE, Cain KL, Heywood SP, et al. Towards a universal disulphide stabilised single chain Fv format: importance of interchain disulphide bond location and vL-vH orientation. Protein Eng Des Sel 2012;25:321-329.
-
(2012)
Protein Eng Des Sel
, vol.25
, pp. 321-329
-
-
Weatherill, E.E.1
Cain, K.L.2
Heywood, S.P.3
-
30
-
-
77249135786
-
Molecular modeling and affinity determination of scFv antibody: Proper linker peptide enhances its activity
-
Gu X, Jia X, Feng J, et al. Molecular modeling and affinity determination of scFv antibody: proper linker peptide enhances its activity. Ann Biomed Eng 2010;38:537-549.
-
(2010)
Ann Biomed Eng
, vol.38
, pp. 537-549
-
-
Gu, X.1
Jia, X.2
Feng, J.3
-
31
-
-
84863241173
-
Expression of a humanized single-chain variable fragment antibody targeting chronic myeloid leukemia cells in Escherichia coli and its characterization
-
Zhu X, Wang D, Li S. Expression of a humanized single-chain variable fragment antibody targeting chronic myeloid leukemia cells in Escherichia coli and its characterization. Int J Mol Med 2012;29:939-945.
-
(2012)
Int J Mol Med
, vol.29
, pp. 939-945
-
-
Zhu, X.1
Wang, D.2
Li, S.3
-
32
-
-
27544506024
-
Engineered recombinant single-chain fragment variable antibody for immunosensors
-
Shen Z, Mernaugh RL, Yan H, et al. Engineered recombinant single-chain fragment variable antibody for immunosensors. Anal Chem 2005;77:6834-6842.
-
(2005)
Anal Chem
, vol.77
, pp. 6834-6842
-
-
Shen, Z.1
Mernaugh, R.L.2
Yan, H.3
-
33
-
-
4143134285
-
Intracellular targeting and functional analysis of single-chain Fv fragments in mammalian cells
-
Cardinale A, Filesi I, Mattei S, Biocca S. Intracellular targeting and functional analysis of single-chain Fv fragments in mammalian cells. Methods 2004;34:171-178.
-
(2004)
Methods
, vol.34
, pp. 171-178
-
-
Cardinale, A.1
Filesi, I.2
Mattei, S.3
Biocca, S.4
-
34
-
-
3242707674
-
Intracellular antibodies as specific reagents for functional ablation: Future therapeutic molecules
-
Lobato MN, Rabbitts TH. Intracellular antibodies as specific reagents for functional ablation: future therapeutic molecules. Curr Mol Med 2004;4:519-528.
-
(2004)
Curr Mol Med
, vol.4
, pp. 519-528
-
-
Lobato, M.N.1
Rabbitts, T.H.2
-
35
-
-
67049155341
-
Single-chain antibodies as diagnostic tools and therapeutic agents
-
Hagemeyer CE, von Zur MC, von ED, Peter K. Single-chain antibodies as diagnostic tools and therapeutic agents. Thromb Haemost 2009;101:1012-1019.
-
(2009)
Thromb Haemost
, vol.101
, pp. 1012-1019
-
-
Hagemeyer, C.E.1
Von Zur, M.C.2
Von, E.D.3
Peter, K.4
-
36
-
-
84872854587
-
Generation and characterization of monospecific and bispecific hexavalent trimerbodies
-
Blanco-Toribio A, Sainz-Pastor N, Alvarez-Cienfuegos A. Generation and characterization of monospecific and bispecific hexavalent trimerbodies. MAbs 2013;5:70-79.
-
(2013)
MAbs
, vol.5
, pp. 70-79
-
-
Blanco-Toribio, A.1
Sainz-Pastor, N.2
Alvarez-Cienfuegos, A.3
-
37
-
-
0026528230
-
Miniantibodies: Use of amphipathic helices to produce functional, flexibly linked dimeric FV fragments with high avidity in Escherichia coli
-
Pack P, Pluckthun A. Miniantibodies: use of amphipathic helices to produce functional, flexibly linked dimeric FV fragments with high avidity in Escherichia coli. Biochemistry 1992;31:1579-1584.
-
(1992)
Biochemistry
, vol.31
, pp. 1579-1584
-
-
Pack, P.1
Pluckthun, A.2
-
38
-
-
0033929947
-
Single-chain antibodies against human insulin-like growth factor I receptor: Expression, purification, and effect on tumor growth
-
Li SL, Liang SJ, Guo N, et al. Single-chain antibodies against human insulin-like growth factor I receptor: expression, purification, and effect on tumor growth. Cancer Immunol Immunother 2000;49:243-252.
-
(2000)
Cancer Immunol Immunother
, vol.49
, pp. 243-252
-
-
Li, S.L.1
Liang, S.J.2
Guo, N.3
-
39
-
-
0029890636
-
Minibody: A novel engineered anti-carcinoembryonic antigen antibody fragment (single-chain Fv-CH3) which exhibits rapid, high-level targeting of xenografts
-
Hu S, Shively L, Raubitschek A, et al. Minibody: a novel engineered anti-carcinoembryonic antigen antibody fragment (single-chain Fv-CH3) which exhibits rapid, high-level targeting of xenografts. Cancer Res 1996;56:3055-3061.
-
(1996)
Cancer Res
, vol.56
, pp. 3055-3061
-
-
Hu, S.1
Shively, L.2
Raubitschek, A.3
-
40
-
-
84860211700
-
Targeted delivery of PLK1-siRNA by ScFv suppresses Her2+breast cancer growth and metastasis
-
Yao YD, Sun TM, Huang SY. Targeted delivery of PLK1-siRNA by ScFv suppresses Her2+breast cancer growth and metastasis. Sci Transl Med 2012;4:130ra48. doi: 10.1126/scitranslmed.3003601.
-
(2012)
Sci Transl Med
, vol.4
, pp. 130ra48
-
-
Yao, Y.D.1
Sun, T.M.2
Huang, S.Y.3
-
41
-
-
84879386361
-
Death signalobody: Inducing conditional cell death in response to a specific antigen
-
Tone Y, Kawahara M, Kawaguchi D, et al. Death signalobody: inducing conditional cell death in response to a specific antigen. Hum Gene Ther Methods 2013;24:141-150.
-
(2013)
Hum Gene Ther Methods
, vol.24
, pp. 141-150
-
-
Tone, Y.1
Kawahara, M.2
Kawaguchi, D.3
-
42
-
-
77951529848
-
Therapeutic antibodies for autoimmunity and inflammation
-
Chan AC, Carter PJ. Therapeutic antibodies for autoimmunity and inflammation. Nat Rev Immunol 2010;10:301-316.
-
(2010)
Nat Rev Immunol
, vol.10
, pp. 301-316
-
-
Chan, A.C.1
Carter, P.J.2
-
43
-
-
34447642376
-
Treatment of non-small cell lung cancer patients with the trifunctional monoclonal antibody catumaxomab (anti-EpCAM x anti-CD3): A phase I study
-
Sebastian M, Passlick B, Friccius-Quecke H. Treatment of non-small cell lung cancer patients with the trifunctional monoclonal antibody catumaxomab (anti-EpCAM x anti-CD3): a phase I study. Cancer Immunol Immunother 2007;56:1637-1644.
-
(2007)
Cancer Immunol Immunother
, vol.56
, pp. 1637-1644
-
-
Sebastian, M.1
Passlick, B.2
Friccius-Quecke, H.3
-
45
-
-
84871491706
-
Long-term follow-up of hematologic relapse-free survival in a phase 2 study of blinatumomab in patients with MRD in B-lineage ALL
-
Topp MS, Gokbuget N, Zugmaier G. Long-term follow-up of hematologic relapse-free survival in a phase 2 study of blinatumomab in patients with MRD in B-lineage ALL. Blood 2012;120:5185-5187.
-
(2012)
Blood
, vol.120
, pp. 5185-5187
-
-
Topp, M.S.1
Gokbuget, N.2
Zugmaier, G.3
-
46
-
-
49649120397
-
Tumor regression in cancer patients by very low doses of a T cell-engaging antibody
-
Bargou R, Leo E, Zugmaier G. Tumor regression in cancer patients by very low doses of a T cell-engaging antibody. Science 2008;321:974-977.
-
(2008)
Science
, vol.321
, pp. 974-977
-
-
Bargou, R.1
Leo, E.2
Zugmaier, G.3
-
47
-
-
63649133396
-
Treatment of malignant pleural effusion with the trifunctional antibody catumaxomab (Removab) (anti-EpCAM x anti-CD3): Results of a phase 1/2 study
-
Sebastian M, Kiewe P, Schuette W. Treatment of malignant pleural effusion with the trifunctional antibody catumaxomab (Removab) (anti-EpCAM x anti-CD3): results of a phase 1/2 study. J Immunother 2009;32:195-202.
-
(2009)
J Immunother
, vol.32
, pp. 195-202
-
-
Sebastian, M.1
Kiewe, P.2
Schuette, W.3
-
48
-
-
50249135564
-
Multivalency: The hallmark of antibodies used for optimization of tumor targeting by design
-
Deyev SM, Lebedenko EN. Multivalency: the hallmark of antibodies used for optimization of tumor targeting by design. Bioessays 2008;30:904-918.
-
(2008)
Bioessays
, vol.30
, pp. 904-918
-
-
Deyev, S.M.1
Lebedenko, E.N.2
-
49
-
-
0347384086
-
Design of multivalent complexes using the barnase∗barstar module
-
Deyev SM, Waibel R, Lebedenko EN, et al. Design of multivalent complexes using the barnase∗barstar module. Nat Biotechnol 2003;21:1486-1492.
-
(2003)
Nat Biotechnol
, vol.21
, pp. 1486-1492
-
-
Deyev, S.M.1
Waibel, R.2
Lebedenko, E.N.3
-
50
-
-
10744221996
-
Selective targeted delivery of TNFalpha to tumor blood vessels
-
Borsi L, Balza E, Carnemolla B, et al. Selective targeted delivery of TNFalpha to tumor blood vessels. Blood 2003;102:4384-4392.
-
(2003)
Blood
, vol.102
, pp. 4384-4392
-
-
Borsi, L.1
Balza, E.2
Carnemolla, B.3
-
51
-
-
0037731516
-
Synergistic therapeutic effects of a tumor targeting antibody fragment, fused to interleukin 12 and to tumor necrosis factor alpha
-
Halin C, Gafner V, Villani ME, et al. Synergistic therapeutic effects of a tumor targeting antibody fragment, fused to interleukin 12 and to tumor necrosis factor alpha. Cancer Res 2003;63:3202-3210.
-
(2003)
Cancer Res
, vol.63
, pp. 3202-3210
-
-
Halin, C.1
Gafner, V.2
Villani, M.E.3
-
52
-
-
33646477258
-
Stably tethered multifunctional structures of defined composition made by the dock and lock method for use in cancer targeting
-
Rossi EA, Goldenberg DM, Cardillo TM, et al. Stably tethered multifunctional structures of defined composition made by the dock and lock method for use in cancer targeting. Proc Natl Acad Sci USA 2006;103:6841-6846.
-
(2006)
Proc Natl Acad Sci USA
, vol.103
, pp. 6841-6846
-
-
Rossi, E.A.1
Goldenberg, D.M.2
Cardillo, T.M.3
-
53
-
-
84862507314
-
A novel bispecific single-chain antibody for ADAM17 and CD3 induces T-cell-mediated lysis of prostate cancer cells
-
Yamamoto K, Trad A, Baumgart A. A novel bispecific single-chain antibody for ADAM17 and CD3 induces T-cell-mediated lysis of prostate cancer cells. Biochem J 2012;445:135-144.
-
(2012)
Biochem J
, vol.445
, pp. 135-144
-
-
Yamamoto, K.1
Trad, A.2
Baumgart, A.3
-
54
-
-
84872752809
-
Isolation and characterisation of a human-like antibody fragment (scFv) that inactivates VEEV in vitro and in vivo
-
Rulker T, Voss L, Thullier P. Isolation and characterisation of a human-like antibody fragment (scFv) that inactivates VEEV in vitro and in vivo. PLoS One 2012;7:e37242.
-
(2012)
PLoS One
, vol.7
, pp. e37242
-
-
Rulker, T.1
Voss, L.2
Thullier, P.3
-
55
-
-
58249122185
-
A bispecific single-chain antibody that mediates target cell-restricted, supra-agonistic CD28 stimulation and killing of lymphoma cells
-
Otz T, Grosse-Hovest L, Hofmann M, et al. A bispecific single-chain antibody that mediates target cell-restricted, supra-agonistic CD28 stimulation and killing of lymphoma cells. Leukemia 2009;23:71-77.
-
(2009)
Leukemia
, vol.23
, pp. 71-77
-
-
Otz, T.1
Grosse-Hovest, L.2
Hofmann, M.3
-
56
-
-
84876574560
-
Rapid optimization and prototyping for therapeutic antibody-like molecules
-
Xu L, Kohli N, Rennard R. Rapid optimization and prototyping for therapeutic antibody-like molecules. MAbs 2013;5:237-254.
-
(2013)
MAbs
, vol.5
, pp. 237-254
-
-
Xu, L.1
Kohli, N.2
Rennard, R.3
-
57
-
-
84866996937
-
Engineering a CD123xCD3 bispecific scFv immunofusion for the treatment of leukemia and elimination of leukemia stem cells
-
Kuo SR, Wong L, Liu JS. Engineering a CD123xCD3 bispecific scFv immunofusion for the treatment of leukemia and elimination of leukemia stem cells. Protein Eng Des Sel 2012;25:561-569.
-
(2012)
Protein Eng Des Sel
, vol.25
, pp. 561-569
-
-
Kuo, S.R.1
Wong, L.2
Liu, J.S.3
-
58
-
-
34548181308
-
Targeting TNF-alpha with a tetravalent mini-antibody TNF-TeAb
-
Liu M, Wang X, Yin C, et al. Targeting TNF-alpha with a tetravalent mini-antibody TNF-TeAb. Biochem J 2007;406:237-246.
-
(2007)
Biochem J
, vol.406
, pp. 237-246
-
-
Liu, M.1
Wang, X.2
Yin, C.3
-
59
-
-
1542681650
-
124I-labeled engineered anti-CEA minibodies and diabodies allow high-contrast, antigen-specific small-animal PET imaging of xenografts in athymic mice
-
124I-labeled engineered anti-CEA minibodies and diabodies allow high-contrast, antigen-specific small-animal PET imaging of xenografts in athymic mice. J Nucl Med 2003;44:1962-1969.
-
(2003)
J Nucl Med
, vol.44
, pp. 1962-1969
-
-
Sundaresan, G.1
Yazaki, P.J.2
Shively, J.E.3
-
60
-
-
77949536402
-
A strategy for adenovirus vector targeting with a secreted single chain antibody
-
Glasgow JN, Mikheeva G, Krasnykh V, Curiel DT. A strategy for adenovirus vector targeting with a secreted single chain antibody. PLoS One 2009;4:e8355.
-
(2009)
PLoS One
, vol.4
, pp. e8355
-
-
Glasgow, J.N.1
Mikheeva, G.2
Krasnykh, V.3
Curiel, D.T.4
-
61
-
-
69849083577
-
Efficient production of human bivalent and trivalent anti-MUC1 Fab-scFv antibodies in Pichia pastoris
-
Schoonooghe S, Kaigorodov V, Zawisza M, et al. Efficient production of human bivalent and trivalent anti-MUC1 Fab-scFv antibodies in Pichia pastoris. BMC Biotechnol 2009;9:70.
-
(2009)
BMC Biotechnol
, vol.9
, pp. 70
-
-
Schoonooghe, S.1
Kaigorodov, V.2
Zawisza, M.3
-
62
-
-
0036793823
-
A phase I trial of the single-chain immunotoxin SGN-10 (BR96 sFv-PE40) in patients with advanced solid tumors
-
Posey JA, Khazaeli MB, Bookman MA. A phase I trial of the single-chain immunotoxin SGN-10 (BR96 sFv-PE40) in patients with advanced solid tumors. Clin Cancer Res 2002;8:3092-3099.
-
(2002)
Clin Cancer Res
, vol.8
, pp. 3092-3099
-
-
Posey, J.A.1
Khazaeli, M.B.2
Bookman, M.A.3
-
63
-
-
84873677208
-
Stability of the recombinant anti-erbB2 scFv-Fc-interleukin2 fusion protein and its inhibition of HER2-overexpressing tumor cells
-
Du YJ, Lin ZM, Zhao YH. Stability of the recombinant anti-erbB2 scFv-Fc-interleukin2 fusion protein and its inhibition of HER2-overexpressing tumor cells. Int J Oncol 2013;42:507-516.
-
(2013)
Int J Oncol
, vol.42
, pp. 507-516
-
-
Du, Y.J.1
Lin, Z.M.2
Zhao, Y.H.3
-
64
-
-
84866452687
-
Antitumor activities of dFv-LDP-AE: An enediyne-energized fusion protein targeting tumor-associated antigen gelatinases
-
Zhong GS, Wu MN, Guo XF, et al. Antitumor activities of dFv-LDP-AE: an enediyne-energized fusion protein targeting tumor-associated antigen gelatinases. Oncol Rep 2012;28:1193-1199.
-
(2012)
Oncol Rep
, vol.28
, pp. 1193-1199
-
-
Zhong, G.S.1
Wu, M.N.2
Guo, X.F.3
-
65
-
-
0024292736
-
Assembly of a functional immunoglobulin Fv fragment in Escherichia coli
-
Skerra A, Pluckthun A. Assembly of a functional immunoglobulin Fv fragment in Escherichia coli. Science 1988;240:1038-1041.
-
(1988)
Science
, vol.240
, pp. 1038-1041
-
-
Skerra, A.1
Pluckthun, A.2
-
66
-
-
33749597339
-
Functional expression of a single-chain antibody to ErbB-2 in plants and cell-free systems
-
Galeffi P, Lombardi A, Pietraforte I, et al. Functional expression of a single-chain antibody to ErbB-2 in plants and cell-free systems. J Transl Med 2006;4:39. doi: 10.1186/1479-5876-4-39.
-
(2006)
J Transl Med
, vol.4
, pp. 39
-
-
Galeffi, P.1
Lombardi, A.2
Pietraforte, I.3
-
67
-
-
33745464891
-
Isolation of anti-CD22 Fv with high affinity by Fv display on human cells
-
Ho M, Nagata S, Pastan I. Isolation of anti-CD22 Fv with high affinity by Fv display on human cells. Proc Natl Acad Sci USA 2006;103:9637-9642.
-
(2006)
Proc Natl Acad Sci USA
, vol.103
, pp. 9637-9642
-
-
Ho, M.1
Nagata, S.2
Pastan, I.3
-
68
-
-
0036451715
-
Soluble expression of a functional recombinant cytolytic immunotoxin in insect cells
-
Choo AB, Dunn RD, Broady KW, Raison RL. Soluble expression of a functional recombinant cytolytic immunotoxin in insect cells. Protein Expr Purif 2002;24:338-347.
-
(2002)
Protein Expr Purif
, vol.24
, pp. 338-347
-
-
Choo, A.B.1
Dunn, R.D.2
Broady, K.W.3
Raison, R.L.4
-
69
-
-
70449524544
-
Improved microtitre plate production of single chain Fv fragments in Escherichia coli
-
Hust M, Steinwand M, Al-Halabi L, et al. Improved microtitre plate production of single chain Fv fragments in Escherichia coli. N Biotechnol 2009;25:424-428.
-
(2009)
N Biotechnol
, vol.25
, pp. 424-428
-
-
Hust, M.1
Steinwand, M.2
Al-Halabi, L.3
-
70
-
-
34648827854
-
A dual expression platform to optimize the soluble production of heterologous proteins in the periplasm of Escherichia coli
-
Kraft M, Knupfer U, Wenderoth R, et al. A dual expression platform to optimize the soluble production of heterologous proteins in the periplasm of Escherichia coli. Appl Microbiol Biotechnol 2007;76:1413-1422.
-
(2007)
Appl Microbiol Biotechnol
, vol.76
, pp. 1413-1422
-
-
Kraft, M.1
Knupfer, U.2
Wenderoth, R.3
-
71
-
-
79953307855
-
Effects of cytoplasmic and periplasmic chaperones on secretory production of single-chain Fv antibody in Escherichia coli
-
Sonoda H, Kumada Y, Katsuda T, Yamaji H. Effects of cytoplasmic and periplasmic chaperones on secretory production of single-chain Fv antibody in Escherichia coli. J Biosci Bioeng 2011;111:465-470.
-
(2011)
J Biosci Bioeng
, vol.111
, pp. 465-470
-
-
Sonoda, H.1
Kumada, Y.2
Katsuda, T.3
Yamaji, H.4
-
72
-
-
84897923580
-
Engineering production of functional scFv antibody in E. coli by co-expressing the molecule chaperone Skp
-
Wang R, Xiang S, Feng Y, et al. Engineering production of functional scFv antibody in E. coli by co-expressing the molecule chaperone Skp. Front Cell Infect Microbiol 2013;3:72. doi:10.3389/fcimb.2013.00072.
-
(2013)
Front Cell Infect Microbiol
, vol.3
, pp. 72
-
-
Wang, R.1
Xiang, S.2
Feng, Y.3
-
73
-
-
33749328523
-
In vitro display technologies reveal novel biopharmaceutics
-
Rothe A, Hosse RJ, Power BE. In vitro display technologies reveal novel biopharmaceutics. FASEB J 2006;20:1599-1610.
-
(2006)
FASEB J
, vol.20
, pp. 1599-1610
-
-
Rothe, A.1
Hosse, R.J.2
Power, B.E.3
-
74
-
-
0346158535
-
Mating antibody phage display with proteomics
-
Hust M, Dubel S. Mating antibody phage display with proteomics. Trends Biotechnol 2004;22:8-14.
-
(2004)
Trends Biotechnol
, vol.22
, pp. 8-14
-
-
Hust, M.1
Dubel, S.2
-
75
-
-
0021818675
-
Filamentous fusion phage: Novel expression vectors that display cloned antigens on the virion surface
-
Smith GP. Filamentous fusion phage: novel expression vectors that display cloned antigens on the virion surface. Science 1985;228:1315-1317.
-
(1985)
Science
, vol.228
, pp. 1315-1317
-
-
Smith, G.P.1
-
76
-
-
84885008151
-
A dual host vector for Fab phage display and expression of native IgG in mammalian cells
-
Tesar D, Hotzel I. A dual host vector for Fab phage display and expression of native IgG in mammalian cells. Protein Eng Des Sel 2013;26:655-662.
-
(2013)
Protein Eng Des Sel
, vol.26
, pp. 655-662
-
-
Tesar, D.1
Hotzel, I.2
-
77
-
-
79251514316
-
Peptide phage display as a tool for drug discovery: Targeting membrane receptors
-
Molek P, Strukelj B, Bratkovic T. Peptide phage display as a tool for drug discovery: targeting membrane receptors. Molecules 2011;16:857-887.
-
(2011)
Molecules
, vol.16
, pp. 857-887
-
-
Molek, P.1
Strukelj, B.2
Bratkovic, T.3
-
78
-
-
33644620264
-
In vitro panning of a targeting peptide to hepatocarcinoma from a phage display peptide library
-
Du B, Qian M, Zhou Z. In vitro panning of a targeting peptide to hepatocarcinoma from a phage display peptide library. Biochem Biophys Res Commun 2006;342:956-962.
-
(2006)
Biochem Biophys Res Commun
, vol.342
, pp. 956-962
-
-
Du, B.1
Qian, M.2
Zhou, Z.3
-
80
-
-
79957617682
-
High affinity, developability and functional size: The holy grail of combinatorial antibody library generation
-
Ponsel D, Neugebauer J, Ladetzki-Baehs K, Tissot K. High affinity, developability and functional size: the holy grail of combinatorial antibody library generation. Molecules 2011;16:3675-3700.
-
(2011)
Molecules
, vol.16
, pp. 3675-3700
-
-
Ponsel, D.1
Neugebauer, J.2
Ladetzki-Baehs, K.3
Tissot, K.4
-
81
-
-
84866631715
-
Transferring the characteristics of naturally occurring and biased antibody repertoires to human antibody libraries by trapping CDRH3 sequences
-
Venet S, Ravn U, Buatois V, et al. Transferring the characteristics of naturally occurring and biased antibody repertoires to human antibody libraries by trapping CDRH3 sequences. PLoS One 2012;7:e43471.
-
(2012)
PLoS One
, vol.7
, pp. e43471
-
-
Venet, S.1
Ravn, U.2
Buatois, V.3
-
82
-
-
0024833055
-
Generation of a large combinatorial library of the immunoglobulin repertoire in phage lambda
-
Huse WD, Sastry L, Iverson SA, et al. Generation of a large combinatorial library of the immunoglobulin repertoire in phage lambda. Science 1989;246:1275-1281.
-
(1989)
Science
, vol.246
, pp. 1275-1281
-
-
Huse, W.D.1
Sastry, L.2
Iverson, S.A.3
-
83
-
-
84896499135
-
Development of neutralizing scFv-Fc against botulinum neurotoxin A light chain from a macaque immune library
-
Miethe S, Rasetti-Escargueil C, Liu Y, et al. Development of neutralizing scFv-Fc against botulinum neurotoxin A light chain from a macaque immune library. MAbs 2014;6:446-459.
-
(2014)
MAbs
, vol.6
, pp. 446-459
-
-
Miethe, S.1
Rasetti-Escargueil, C.2
Liu, Y.3
-
84
-
-
84862499652
-
Generation of a highly reactive chicken-derived single-chain variable fragment against Fusarium verticillioides by phage display
-
Hu ZQ, Liu JL, Li HP. Generation of a highly reactive chicken-derived single-chain variable fragment against Fusarium verticillioides by phage display. Int J Mol Sci 2012;13:7038-7056.
-
(2012)
Int J Mol Sci
, vol.13
, pp. 7038-7056
-
-
Hu, Z.Q.1
Liu, J.L.2
Li, H.P.3
-
85
-
-
0026317443
-
By-passing immunization. Human antibodies from V-gene libraries displayed on phage
-
Marks JD, Hoogenboom HR, Bonnert TP, et al. By-passing immunization. Human antibodies from V-gene libraries displayed on phage. J Mol Biol 1991;222:581-597.
-
(1991)
J Mol Biol
, vol.222
, pp. 581-597
-
-
Marks, J.D.1
Hoogenboom, H.R.2
Bonnert, T.P.3
-
86
-
-
84876121952
-
Discovery of diverse and functional antibodies from large human repertoire antibody libraries
-
Schwimmer LJ, Huang B, Giang H, et al. Discovery of diverse and functional antibodies from large human repertoire antibody libraries. J Immunol Methods 2013;391:60-71.
-
(2013)
J Immunol Methods
, vol.391
, pp. 60-71
-
-
Schwimmer, L.J.1
Huang, B.2
Giang, H.3
-
87
-
-
21144443760
-
Construction, evaluation and refinement of a large human antibody phage library based on the IgD and IgM variable gene repertoire
-
Loset GA, Lobersli I, Kavlie A, et al. Construction, evaluation and refinement of a large human antibody phage library based on the IgD and IgM variable gene repertoire. J Immunol Methods 2005;299:47-62.
-
(2005)
J Immunol Methods
, vol.299
, pp. 47-62
-
-
Loset, G.A.1
Lobersli, I.2
Kavlie, A.3
-
88
-
-
9344223986
-
Human antibodies with sub-nanomolar affinities isolated from a large non-immunized phage display library
-
Vaughan TJ, Williams AJ, Pritchard K, et al. Human antibodies with sub-nanomolar affinities isolated from a large non-immunized phage display library. Nat Biotechnol 1996;14:309-314.
-
(1996)
Nat Biotechnol
, vol.14
, pp. 309-314
-
-
Vaughan, T.J.1
Williams, A.J.2
Pritchard, K.3
-
89
-
-
60749123372
-
Modelling the human immune response: Performance of a 1011 human antibody repertoire against a broad panel of herapeutically relevant antigens
-
Lloyd C, Lowe D, Edwards B, et al. Modelling the human immune response: performance of a 1011 human antibody repertoire against a broad panel of herapeutically relevant antigens. Protein Eng Des Sel 2009;22:159-168.
-
(2009)
Protein Eng Des Sel
, vol.22
, pp. 159-168
-
-
Lloyd, C.1
Lowe, D.2
Edwards, B.3
-
90
-
-
84863455412
-
An efficient method for variable region assembly in the construction of scFv phage display libraries using independent strand amplification
-
Sotelo P, Collazo N, Zuniga R. An efficient method for variable region assembly in the construction of scFv phage display libraries using independent strand amplification. MAbs 2012;4:542-550.
-
(2012)
MAbs
, vol.4
, pp. 542-550
-
-
Sotelo, P.1
Collazo, N.2
Zuniga, R.3
-
91
-
-
0033883409
-
Recombining germline-derived CDR sequences for creating diverse single-framework antibody libraries
-
Soderlind E, Strandberg L, Jirholt P, et al. Recombining germline-derived CDR sequences for creating diverse single-framework antibody libraries. Nat Biotechnol 2000;18:852-856.
-
(2000)
Nat Biotechnol
, vol.18
, pp. 852-856
-
-
Soderlind, E.1
Strandberg, L.2
Jirholt, P.3
-
92
-
-
0033103199
-
Complementarity-determining region (CDR) implantation: A theme of recombination
-
Soderlind E, Ohlin M, Carlsson R. Complementarity-determining region (CDR) implantation: a theme of recombination. Immunotechnology 1999;4:279-285.
-
(1999)
Immunotechnology
, vol.4
, pp. 279-285
-
-
Soderlind, E.1
Ohlin, M.2
Carlsson, R.3
-
93
-
-
0037035423
-
Rapid selection of anti-hapten antibodies isolated from synthetic and semi-synthetic antibody phage display libraries expressed in Escherichia coli
-
Strachan G, McElhiney J, Drever M, et al. Rapid selection of anti-hapten antibodies isolated from synthetic and semi-synthetic antibody phage display libraries expressed in Escherichia coli. FEMS Microbiol Lett 2006;210:257-261.
-
(2006)
FEMS Microbiol Lett
, vol.210
, pp. 257-261
-
-
Strachan, G.1
McElhiney, J.2
Drever, M.3
-
94
-
-
0028291823
-
Isolation of high affinity human antibodies directly from large synthetic repertoires
-
Griffiths AD, Williams SC, Hartley O, et al. Isolation of high affinity human antibodies directly from large synthetic repertoires. EMBO J 1994;13:3245-3260.
-
(1994)
EMBO J
, vol.13
, pp. 3245-3260
-
-
Griffiths, A.D.1
Williams, S.C.2
Hartley, O.3
-
95
-
-
0032555478
-
Design and use of a phage display library. Human antibodies with subnanomolar affinity against a marker of angiogenesis eluted from a two-dimensional gel
-
Pini A, Viti F, Santucci A, et al. Design and use of a phage display library. Human antibodies with subnanomolar affinity against a marker of angiogenesis eluted from a two-dimensional gel. J Biol Chem 1998;273:21769-21776.
-
(1998)
J Biol Chem
, vol.273
, pp. 21769-21776
-
-
Pini, A.1
Viti, F.2
Santucci, A.3
-
96
-
-
79955650818
-
A novel synthetic naive human antibody library allows the isolation of antibodies against a new epitope of oncofetal fibronectin
-
Villa A, Lovato V, Bujak E, et al. A novel synthetic naive human antibody library allows the isolation of antibodies against a new epitope of oncofetal fibronectin. MAbs 2011;3:264-272.
-
(2011)
MAbs
, vol.3
, pp. 264-272
-
-
Villa, A.1
Lovato, V.2
Bujak, E.3
-
97
-
-
0030772225
-
Construction of a semisynthetic antibody library using trinucleotide oligos
-
Braunagel M, Little M. Construction of a semisynthetic antibody library using trinucleotide oligos. Nucleic Acids Res 1997;25:4690-4691.
-
(1997)
Nucleic Acids Res
, vol.25
, pp. 4690-4691
-
-
Braunagel, M.1
Little, M.2
-
98
-
-
0034635335
-
Fully synthetic human combinatorial antibody libraries (HuCAL) based on modular consensus frameworks and CDRs randomized with trinucleotides
-
Knappik A, Ge L, Honegger A, et al. Fully synthetic human combinatorial antibody libraries (HuCAL) based on modular consensus frameworks and CDRs randomized with trinucleotides. J Mol Biol 2000;296:57-86.
-
(2000)
J Mol Biol
, vol.296
, pp. 57-86
-
-
Knappik, A.1
Ge, L.2
Honegger, A.3
-
99
-
-
70349644972
-
Neutralizing antibodies of botulinum neurotoxin serotype A screened from a fully synthetic human antibody phage display library
-
Yu R, Wang S, Yu YZ, et al. Neutralizing antibodies of botulinum neurotoxin serotype A screened from a fully synthetic human antibody phage display library. J Biomol Screen 2009;14:991-998.
-
(2009)
J Biomol Screen
, vol.14
, pp. 991-998
-
-
Yu, R.1
Wang, S.2
Yu, Y.Z.3
-
100
-
-
0036366705
-
Overview of antibody phage-display technology and its applications
-
Hoogenboom HR. Overview of antibody phage-display technology and its applications. Methods Mol Biol 2002;178:1-37.
-
(2002)
Methods Mol Biol
, vol.178
, pp. 1-37
-
-
Hoogenboom, H.R.1
-
101
-
-
0028291823
-
Isolation of high affinity human antibodies directly from large synthetic repertoires
-
Griffiths AD, Williams SC, Hartley O. Isolation of high affinity human antibodies directly from large synthetic repertoires. EMBO J 1994;13:3245-3260.
-
(1994)
EMBO J
, vol.13
, pp. 3245-3260
-
-
Griffiths, A.D.1
Williams, S.C.2
Hartley, O.3
-
102
-
-
9344223986
-
Human antibodies with sub-nanomolar affinities isolated from a large non-immunized phage display library
-
Vaughan TJ, Williams AJ, Pritchard K, et al. Human antibodies with sub-nanomolar affinities isolated from a large non-immunized phage display library. Nat Biotechnol 1996;14:309-314.
-
(1996)
Nat Biotechnol
, vol.14
, pp. 309-314
-
-
Vaughan, T.J.1
Williams, A.J.2
Pritchard, K.3
-
103
-
-
13144261717
-
Efficient construction of a large nonimmune phage antibody library: The production of high-affinity human single-chain antibodies to protein antigens
-
Sheets MD, Amersdorfer P, Finnern R, et al. Efficient construction of a large nonimmune phage antibody library: the production of high-affinity human single-chain antibodies to protein antigens. Proc Natl Acad Sci USA 1998;95:6157-6162.
-
(1998)
Proc Natl Acad Sci USA
, vol.95
, pp. 6157-6162
-
-
Sheets, M.D.1
Amersdorfer, P.2
Finnern, R.3
-
104
-
-
84855179210
-
Screening for antibodies against intact cancer cells with a naive large phage antibody library
-
Qiao Y, Zhou L, Wang Y. Screening for antibodies against intact cancer cells with a naive large phage antibody library. Int J Mol Med 2012;29:37-46.
-
(2012)
Int J Mol Med
, vol.29
, pp. 37-46
-
-
Qiao, Y.1
Zhou, L.2
Wang, Y.3
-
105
-
-
36949002708
-
Modification and identification of a vector for making a large phage antibody library
-
Zhang GM, Chen YP, Guan YZ, et al. Modification and identification of a vector for making a large phage antibody library. Chin Med J 2007;120:2011-2016.
-
(2007)
Chin Med J
, vol.120
, pp. 2011-2016
-
-
Zhang, G.M.1
Chen, Y.P.2
Guan, Y.Z.3
-
106
-
-
60549116209
-
A compact phage display human scFv library for selection of antibodies to a wide variety of antigens
-
Pansri P, Jaruseranee N, Rangnoi K, et al. A compact phage display human scFv library for selection of antibodies to a wide variety of antigens. BMC Biotechnol 2009;9:6.
-
(2009)
BMC Biotechnol
, vol.9
, pp. 6
-
-
Pansri, P.1
Jaruseranee, N.2
Rangnoi, K.3
-
107
-
-
0037026254
-
Cell-Surface display of heterologous proteins: From high-throughput screening to environmental applications
-
Chen W, Georgiou G. Cell-Surface display of heterologous proteins: from high-throughput screening to environmental applications. Biotechnol Bioeng 2002;79:496-503.
-
(2002)
Biotechnol Bioeng
, vol.79
, pp. 496-503
-
-
Chen, W.1
Georgiou, G.2
-
108
-
-
10444241949
-
Biotechnological applications for surface-engineered bacteria
-
Wernerus H, Stahl S. Biotechnological applications for surface-engineered bacteria. Biotechnol Appl Biochem 2004;40:209-228.
-
(2004)
Biotechnol Appl Biochem
, vol.40
, pp. 209-228
-
-
Wernerus, H.1
Stahl, S.2
-
109
-
-
0031663081
-
Antibody affinity maturation using bacterial surface display
-
Daugherty PS, Chen G, Olsen MJ, et al. Antibody affinity maturation using bacterial surface display. Protein Eng 1998;11:825-832.
-
(1998)
Protein Eng
, vol.11
, pp. 825-832
-
-
Daugherty, P.S.1
Chen, G.2
Olsen, M.J.3
-
110
-
-
0343580440
-
Flow cytometric quantification of surface-displayed recombinant receptors on staphylococci
-
Andreoni C, Goetsch L, Libon C, et al. Flow cytometric quantification of surface-displayed recombinant receptors on staphylococci. Biotechniques 1997;23:696-702,704.
-
(1997)
Biotechniques
, vol.23
, pp. 696-702+704
-
-
Andreoni, C.1
Goetsch, L.2
Libon, C.3
-
111
-
-
0030994634
-
Yeast surface display for screening combinatorial polypeptide libraries
-
Boder ET, Wittrup KD. Yeast surface display for screening combinatorial polypeptide libraries. Nat Biotechnol 1997;15:553-557.
-
(1997)
Nat Biotechnol
, vol.15
, pp. 553-557
-
-
Boder, E.T.1
Wittrup, K.D.2
-
112
-
-
33947424302
-
Mining a yeast library for brain endothelial cell-binding antibodies
-
Wang XX, Cho YK, Shusta EV. Mining a yeast library for brain endothelial cell-binding antibodies. Nat Methods 2007;4:143-145.
-
(2007)
Nat Methods
, vol.4
, pp. 143-145
-
-
Wang, X.X.1
Cho, Y.K.2
Shusta, E.V.3
-
113
-
-
84869136138
-
Using phage and yeast display to select hundreds of monoclonal antibodies: Application to antigen 85, a tuberculosis biomarker
-
Ferrara F, Naranjo LA, Kumar S, et al. Using phage and yeast display to select hundreds of monoclonal antibodies: application to antigen 85, a tuberculosis biomarker. PLoS One 2012;7:e49535.
-
(2012)
PLoS One
, vol.7
, pp. e49535
-
-
Ferrara, F.1
Naranjo, L.A.2
Kumar, S.3
-
114
-
-
59249086876
-
A yeast display immunoprecipitation method for efficient isolation and characterization of antigens
-
Cho YK, Chen I, Wei X, et al. A yeast display immunoprecipitation method for efficient isolation and characterization of antigens. J Immunol Methods 2009;341:117-126.
-
(2009)
J Immunol Methods
, vol.341
, pp. 117-126
-
-
Cho, Y.K.1
Chen, I.2
Wei, X.3
-
115
-
-
84860562842
-
Validation of glypican-3-specific scFv isolated from paired display/secretory yeast display library
-
Li Y, Siegel DL, Scholler N, Kaplan DE. Validation of glypican-3-specific scFv isolated from paired display/secretory yeast display library. BMC Biotechnol 2012;12:23.
-
(2012)
BMC Biotechnol
, vol.12
, pp. 23
-
-
Li, Y.1
Siegel, D.L.2
Scholler, N.3
Kaplan, D.E.4
-
116
-
-
84872290942
-
Antibody affinity maturation using yeast display with detergent-solubilized membrane proteins as antigen sources
-
Tillotson BJ, de Larrinoa IF, Skinner CA, et al. Antibody affinity maturation using yeast display with detergent-solubilized membrane proteins as antigen sources. Protein Eng Des Sel 2013;26:101-112.
-
(2013)
Protein Eng Des Sel
, vol.26
, pp. 101-112
-
-
Tillotson, B.J.1
De Larrinoa, I.F.2
Skinner, C.A.3
-
117
-
-
84897847392
-
Construction of a large synthetic human fab antibody library on yeast cell surface by optimized yeast mating
-
Baek DS, Kim YS. Construction of a large synthetic human fab antibody library on yeast cell surface by optimized yeast mating. J Microbiol Biotechnol 2014;24:408-420.
-
(2014)
J Microbiol Biotechnol
, vol.24
, pp. 408-420
-
-
Baek, D.S.1
Kim, Y.S.2
-
118
-
-
0027425230
-
Production and fluorescence-activated cell sorting of Escherichia coli expressing a functional antibody fragment on the external surface
-
Francisco JA, Campbell R, Iverson BL, Georgiou G. Production and fluorescence-activated cell sorting of Escherichia coli expressing a functional antibody fragment on the external surface. Proc Natl Acad Sci USA 1993;90:10444-10448.
-
(1993)
Proc Natl Acad Sci USA
, vol.90
, pp. 10444-10448
-
-
Francisco, J.A.1
Campbell, R.2
Iverson, B.L.3
Georgiou, G.4
-
119
-
-
3042647616
-
Anchored periplasmic expression, a versatile technology for the isolation of high-affinity antibodies from Escherichia coli-expressed libraries
-
Harvey BR, Georgiou G, Hayhurst A, et al. Anchored periplasmic expression, a versatile technology for the isolation of high-affinity antibodies from Escherichia coli-expressed libraries. Proc Natl Acad Sci USA 2004;101:9193-9198.
-
(2004)
Proc Natl Acad Sci USA
, vol.101
, pp. 9193-9198
-
-
Harvey, B.R.1
Georgiou, G.2
Hayhurst, A.3
-
120
-
-
84869070089
-
Single-cell characterization of autotransporter-mediated Escherichia coli surface display of disulfide bond-containing proteins
-
Ramesh B, Sendra VG, Cirino PC, Varadarajan N. Single-cell characterization of autotransporter-mediated Escherichia coli surface display of disulfide bond-containing proteins. J Biol Chem 2012;287:38580-38589.
-
(2012)
J Biol Chem
, vol.287
, pp. 38580-38589
-
-
Ramesh, B.1
Sendra, V.G.2
Cirino, P.C.3
Varadarajan, N.4
-
121
-
-
33748307400
-
Cell-free translation systems for protein engineering
-
Shimizu Y, Kuruma Y, Ying BW, et al. Cell-free translation systems for protein engineering. FEBS J 2006;273:4133-4140.
-
(2006)
FEBS J
, vol.273
, pp. 4133-4140
-
-
Shimizu, Y.1
Kuruma, Y.2
Ying, B.W.3
-
122
-
-
84868285698
-
In vitro selection of fab fragments by mRNA display and gene-linking emulsion PCR
-
Sumida T, Yanagawa H, Doi N. In vitro selection of fab fragments by mRNA display and gene-linking emulsion PCR. J Nucleic Acids 2012;2012:371379.
-
(2012)
J Nucleic Acids
, vol.2012
, pp. 371379
-
-
Sumida, T.1
Yanagawa, H.2
Doi, N.3
-
123
-
-
0028592703
-
An in vitro polysome display system for identifying ligands from very large peptide libraries
-
Mattheakis LC, Bhatt RR, Dower WJ. An in vitro polysome display system for identifying ligands from very large peptide libraries. Proc Natl Acad Sci USA 1994;91:9022-9026.
-
(1994)
Proc Natl Acad Sci USA
, vol.91
, pp. 9022-9026
-
-
Mattheakis, L.C.1
Bhatt, R.R.2
Dower, W.J.3
-
124
-
-
0031574037
-
Antibody-ribosome-mRNA (ARM) complexes as efficient selection particles for in vitro display and evolution of antibody combining sites
-
He M, Taussig MJ. Antibody-ribosome-mRNA (ARM) complexes as efficient selection particles for in vitro display and evolution of antibody combining sites. Nucleic Acids Res 1997;25:5132-5134.
-
(1997)
Nucleic Acids Res
, vol.25
, pp. 5132-5134
-
-
He, M.1
Taussig, M.J.2
-
125
-
-
0030974119
-
In vitro selection and evolution of functional proteins by using ribosome display
-
Hanes J, Pluckthun A. In vitro selection and evolution of functional proteins by using ribosome display. Proc Natl Acad Sci USA 1997;94:4937-4942.
-
(1997)
Proc Natl Acad Sci USA
, vol.94
, pp. 4937-4942
-
-
Hanes, J.1
Pluckthun, A.2
-
126
-
-
84855900988
-
Selection of single-chain variable fragment antibodies against fenitrothion by ribosome display
-
Luo Y, Xia Y. Selection of single-chain variable fragment antibodies against fenitrothion by ribosome display. Anal Biochem 2012;421:130-137.
-
(2012)
Anal Biochem
, vol.421
, pp. 130-137
-
-
Luo, Y.1
Xia, Y.2
-
127
-
-
0033664270
-
Picomolar affinity antibodies from a fully synthetic naive library selected and evolved by ribosome display
-
Hanes J, Schaffitzel C, Knappik A, Pluckthun A. Picomolar affinity antibodies from a fully synthetic naive library selected and evolved by ribosome display. Nat Biotechnol 2000;18:1287-1292.
-
(2000)
Nat Biotechnol
, vol.18
, pp. 1287-1292
-
-
Hanes, J.1
Schaffitzel, C.2
Knappik, A.3
Pluckthun, A.4
-
128
-
-
69249182963
-
Selection of scFvs specific for the HepG2 cell line using ribosome display
-
Zhou L, Mao WP, Fen J, et al. Selection of scFvs specific for the HepG2 cell line using ribosome display. J Biosci 2009;34:221-226.
-
(2009)
J Biosci
, vol.34
, pp. 221-226
-
-
Zhou, L.1
Mao, W.P.2
Fen, J.3
-
129
-
-
0029914040
-
Metal binding properties of a monoclonal antibody directed toward metal-chelate complexes
-
Blake DA, Chakrabarti P, Khosraviani M. Metal binding properties of a monoclonal antibody directed toward metal-chelate complexes. J Biol Chem 1996;271:27677-27685.
-
(1996)
J Biol Chem
, vol.271
, pp. 27677-27685
-
-
Blake, D.A.1
Chakrabarti, P.2
Khosraviani, M.3
-
130
-
-
69949175189
-
In vitro selection of scFv and its production: An application of mRNA display and wheat embryo cell-free and E. coli cell production system
-
Shibui T, Kobayashi T, Kanatani K, et al. In vitro selection of scFv and its production: an application of mRNA display and wheat embryo cell-free and E. coli cell production system. Appl Microbiol Biotechnol 2009;84:725-732.
-
(2009)
Appl Microbiol Biotechnol
, vol.84
, pp. 725-732
-
-
Shibui, T.1
Kobayashi, T.2
Kanatani, K.3
-
131
-
-
21144480358
-
Cell-free cotranslation and selection using in vitro virus for high-throughput analysis of protein-protein interactions and complexes
-
Miyamoto-Sato E, Ishizaka M, Horisawa K, et al. Cell-free cotranslation and selection using in vitro virus for high-throughput analysis of protein-protein interactions and complexes. Genome Res 2005;15:710-717.
-
(2005)
Genome Res
, vol.15
, pp. 710-717
-
-
Miyamoto-Sato, E.1
Ishizaka, M.2
Horisawa, K.3
-
132
-
-
0021818675
-
Filamentous fusion phage: Novel expression vectors that display cloned antigens on the virion surface
-
Smith GP. Filamentous fusion phage: novel expression vectors that display cloned antigens on the virion surface. Science 1985;228:1315-1317.
-
(1985)
Science
, vol.228
, pp. 1315-1317
-
-
Smith, G.P.1
-
133
-
-
33750982135
-
In vitro evolution of single-chain antibodies using mRNA display
-
Fukuda I, Kojoh K, Tabata N. In vitro evolution of single-chain antibodies using mRNA display. Nucleic Acids Res 2006;34:e127. doi: 10.1093/nar/gkl618.
-
(2006)
Nucleic Acids Res
, vol.34
, pp. e127
-
-
Fukuda, I.1
Kojoh, K.2
Tabata, N.3
-
134
-
-
26644448210
-
Selection of functional human antibodies from retroviral display libraries
-
Urban JH, Schneider RM, Compte M, et al. Selection of functional human antibodies from retroviral display libraries. Nucleic Acids Res 2005;33:e35. doi: 10.1093/nar/gni033.
-
(2005)
Nucleic Acids Res
, vol.33
, pp. e35
-
-
Urban, J.H.1
Schneider, R.M.2
Compte, M.3
-
135
-
-
77958534289
-
Development of a novel mammalian cell surface antibody display platform
-
Zhou C, Jacobsen FW, Cai L, et al. Development of a novel mammalian cell surface antibody display platform. MAbs 2010;2:508-518.
-
(2010)
MAbs
, vol.2
, pp. 508-518
-
-
Zhou, C.1
Jacobsen, F.W.2
Cai, L.3
-
136
-
-
33745464891
-
Isolation of anti-CD22 Fv with high affinity by Fv display on human cells
-
Ho M, Nagata S, Pastan I. Isolation of anti-CD22 Fv with high affinity by Fv display on human cells. Proc Natl Acad Sci USA 2006;103:9637-9642.
-
(2006)
Proc Natl Acad Sci USA
, vol.103
, pp. 9637-9642
-
-
Ho, M.1
Nagata, S.2
Pastan, I.3
-
137
-
-
84862909342
-
Coupling mammalian cell surface display with somatic hypermutation for the discovery and maturation of human antibodies
-
Bowers PM, Horlick RA, Neben TY, et al. Coupling mammalian cell surface display with somatic hypermutation for the discovery and maturation of human antibodies. Proc Natl Acad Sci USA 2011;108:20455-20460.
-
(2011)
Proc Natl Acad Sci USA
, vol.108
, pp. 20455-20460
-
-
Bowers, P.M.1
Horlick, R.A.2
Neben, T.Y.3
-
138
-
-
70349481831
-
Lymphocyte display: A novel antibody selection platform based on T cell activation
-
Alonso-Camino V, Sanchez-Martin D, Compte M, et al. Lymphocyte display: a novel antibody selection platform based on T cell activation. PLoS One 2009;4:e7174.
-
(2009)
PLoS One
, vol.4
, pp. e7174
-
-
Alonso-Camino, V.1
Sanchez-Martin, D.2
Compte, M.3
-
139
-
-
84878881427
-
CARbodies: Human antibodies against cell surface tumor antigens selected from repertoires displayed on T cell chimeric antigen receptors
-
Alonso-Camino V, Sanchez-Martin D, Compte M, et al. CARbodies: human antibodies against cell surface tumor antigens selected from repertoires displayed on T cell chimeric antigen receptors. Mol Ther Nucleic Acids 2013;2:e93. doi: 10.1038/mtna.2013.19.
-
(2013)
Mol Ther Nucleic Acids
, vol.2
, pp. e93
-
-
Alonso-Camino, V.1
Sanchez-Martin, D.2
Compte, M.3
-
140
-
-
84872860801
-
Baculovirus superinfection: A probable restriction factor on the surface display of proteins for library screening
-
Xu X, Chen Y, Zhao Y, et al. Baculovirus superinfection: a probable restriction factor on the surface display of proteins for library screening. PLoS One 2013;8:e54631.
-
(2013)
PLoS One
, vol.8
, pp. e54631
-
-
Xu, X.1
Chen, Y.2
Zhao, Y.3
-
141
-
-
78349298326
-
Baculovirus display of single chain antibody (scFv) using a novel signal peptide
-
Kitidee K, Nangola S, Gonzalez G, et al. Baculovirus display of single chain antibody (scFv) using a novel signal peptide. BMC Biotechnol 2010;10:80.
-
(2010)
BMC Biotechnol
, vol.10
, pp. 80
-
-
Kitidee, K.1
Nangola, S.2
Gonzalez, G.3
-
142
-
-
52649158251
-
Lentivirus display: Stable expression of human antibodies on the surface of human cells and virus particles
-
Taube R, Zhu Q, Xu C, et al. Lentivirus display: stable expression of human antibodies on the surface of human cells and virus particles. PLoS One 2008;3:e3181.
-
(2008)
PLoS One
, vol.3
, pp. e3181
-
-
Taube, R.1
Zhu, Q.2
Xu, C.3
-
143
-
-
50249132634
-
Antibody therapeutics, antibody engineering, and the merits of protein stability
-
Demarest SJ, Glaser SM. Antibody therapeutics, antibody engineering, and the merits of protein stability. Curr Opin Drug Discov Devel 2008;11:675-687.
-
(2008)
Curr Opin Drug Discov Devel
, vol.11
, pp. 675-687
-
-
Demarest, S.J.1
Glaser, S.M.2
-
144
-
-
77956807939
-
Retargeting of adenovirus vectors through genetic fusion of a single-chain or single-domain antibody to capsid protein IX
-
Poulin KL, Lanthier RM, Smith AC. Retargeting of adenovirus vectors through genetic fusion of a single-chain or single-domain antibody to capsid protein IX. J Virol 2010;84:10074-10086.
-
(2010)
J Virol
, vol.84
, pp. 10074-10086
-
-
Poulin, K.L.1
Lanthier, R.M.2
Smith, A.C.3
-
145
-
-
0035793208
-
Stability engineering of antibody single-chain Fv fragments
-
Worn A, Pluckthun A. Stability engineering of antibody single-chain Fv fragments. J Mol Bio 2001;305:989-1010.
-
(2001)
J Mol Bio
, vol.305
, pp. 989-1010
-
-
Worn, A.1
Pluckthun, A.2
-
146
-
-
12844267487
-
In vitro antibody evolution targeting germline hot spots to increase activity of an anti-CD22 immunotoxin
-
Ho M, Kreitman RJ, Onda M, Pastan I. In vitro antibody evolution targeting germline hot spots to increase activity of an anti-CD22 immunotoxin. J Biol Chem 2005;280:607-617.
-
(2005)
J Biol Chem
, vol.280
, pp. 607-617
-
-
Ho, M.1
Kreitman, R.J.2
Onda, M.3
Pastan, I.4
-
147
-
-
78651370060
-
Light-chain shuffling from an antigen-biased phage pool allows 185-fold improvement of an anti-halofuginone single-chain variable fragment
-
Fitzgerald J, Leonard P, Darcy E, et al. Light-chain shuffling from an antigen-biased phage pool allows 185-fold improvement of an anti-halofuginone single-chain variable fragment. Anal Biochem 2011;410:27-33.
-
(2011)
Anal Biochem
, vol.410
, pp. 27-33
-
-
Fitzgerald, J.1
Leonard, P.2
Darcy, E.3
-
148
-
-
0030575802
-
Isolation of picomolar affinity anti-c-erbB-2 single-chain Fv by molecular evolution of the complementarity determining regions in the center of the antibody binding site
-
Schier R, McCall A, Adams GP, et al. Isolation of picomolar affinity anti-c-erbB-2 single-chain Fv by molecular evolution of the complementarity determining regions in the center of the antibody binding site. J Mol Biol 1996;263:551-567.
-
(1996)
J Mol Biol
, vol.263
, pp. 551-567
-
-
Schier, R.1
McCall, A.2
Adams, G.P.3
-
149
-
-
0029989324
-
Isolation of high-affinity monomeric human anti-c-erbB-2 single chain Fv using affinity-driven selection
-
Schier R, Bye J, Apell G, et al. Isolation of high-affinity monomeric human anti-c-erbB-2 single chain Fv using affinity-driven selection. J Mol Biol 1996;255:28-43.
-
(1996)
J Mol Biol
, vol.255
, pp. 28-43
-
-
Schier, R.1
Bye, J.2
Apell, G.3
-
150
-
-
68149158702
-
Selection of anti-sulfadimidine specific ScFvs from a hybridoma cell by eukaryotic ribosome display
-
Qi Y, Wu C, Zhang S, et al. Selection of anti-sulfadimidine specific ScFvs from a hybridoma cell by eukaryotic ribosome display. PLoS One 2009;4:e6427.
-
(2009)
PLoS One
, vol.4
, pp. e6427
-
-
Qi, Y.1
Wu, C.2
Zhang, S.3
-
151
-
-
20844463814
-
A general method for greatly improving the affinity of antibodies by using combinatorial libraries
-
Rajpal A, Beyaz N, Haber L, et al. A general method for greatly improving the affinity of antibodies by using combinatorial libraries. Proc Natl Acad Sci USA 2005;102:8466-8471.
-
(2005)
Proc Natl Acad Sci USA
, vol.102
, pp. 8466-8471
-
-
Rajpal, A.1
Beyaz, N.2
Haber, L.3
-
152
-
-
84905268179
-
Affinity improvement of a therapeutic antibody to methamphetamine and amphetamine through structure-based antibody engineering
-
Thakkar S, Nanaware-Kharade N, Celikel R, et al. Affinity improvement of a therapeutic antibody to methamphetamine and amphetamine through structure-based antibody engineering. Sci Rep 2014;4:3673. doi: 10.1038/srep03673.
-
(2014)
Sci Rep
, vol.4
, pp. 3673
-
-
Thakkar, S.1
Nanaware-Kharade, N.2
Celikel, R.3
-
153
-
-
79251610615
-
Stabilization of the single-chain fragment variable by an interdomain disulfide bond and its effect on antibody affinity
-
Zhao JX, Yang L, Gu ZN, et al. Stabilization of the single-chain fragment variable by an interdomain disulfide bond and its effect on antibody affinity. Int J Mol Sci 2010;12:1-11.
-
(2010)
Int J Mol Sci
, vol.12
, pp. 1-11
-
-
Zhao, J.X.1
Yang, L.2
Gu, Z.N.3
-
154
-
-
0031663081
-
Antibody affinity maturation using bacterial surface display
-
Daugherty PS, Chen G, Olsen MJ, et al. Antibody affinity maturation using bacterial surface display. Protein Eng 1998;11:825-832.
-
(1998)
Protein Eng
, vol.11
, pp. 825-832
-
-
Daugherty, P.S.1
Chen, G.2
Olsen, M.J.3
-
155
-
-
0032797898
-
Development of an optimized expression system for the screening of antibody libraries displayed on the Escherichia coli surface
-
Daugherty PS, Olsen MJ, Iverson BL, Georgiou G. Development of an optimized expression system for the screening of antibody libraries displayed on the Escherichia coli surface. Protein Eng 1999;12:613-621.
-
(1999)
Protein Eng
, vol.12
, pp. 613-621
-
-
Daugherty, P.S.1
Olsen, M.J.2
Iverson, B.L.3
Georgiou, G.4
-
156
-
-
84860381852
-
A novel disulfide-stabilized single-chain variable antibody fragment against rabies virus G protein with enhanced in vivo neutralizing potency
-
Duan Y, Gu TJ, Jiang CL. A novel disulfide-stabilized single-chain variable antibody fragment against rabies virus G protein with enhanced in vivo neutralizing potency. Mol Immunol 2012;51:188-196.
-
(2012)
Mol Immunol
, vol.51
, pp. 188-196
-
-
Duan, Y.1
Gu, T.J.2
Jiang, C.L.3
-
157
-
-
72449130972
-
New strategy for the extension of the serum half-life of antibody fragments
-
Trussel S, Dumelin C, Frey K, et al. New strategy for the extension of the serum half-life of antibody fragments. Bioconjug Chem 2009;20:2286-2292.
-
(2009)
Bioconjug Chem
, vol.20
, pp. 2286-2292
-
-
Trussel, S.1
Dumelin, C.2
Frey, K.3
-
158
-
-
84882393963
-
Single-chain variable fragment albumin fusions bind the neonatal Fc receptor (FcRn) in a species-dependent manner: Implications for in vivo half-life evaluation of albumin fusion therapeutics
-
Andersen JT, Cameron J, Plumridge A, et al. Single-chain variable fragment albumin fusions bind the neonatal Fc receptor (FcRn) in a species-dependent manner: implications for in vivo half-life evaluation of albumin fusion therapeutics. J Biol Chem 2013;288:24277-24285.
-
(2013)
J Biol Chem
, vol.288
, pp. 24277-24285
-
-
Andersen, J.T.1
Cameron, J.2
Plumridge, A.3
-
159
-
-
79955665534
-
Engineering the variable region of therapeutic IgG antibodies
-
Igawa T, Tsunoda H, Kuramochi T, et al. Engineering the variable region of therapeutic IgG antibodies. MAbs 2011;3:243-252.
-
(2011)
MAbs
, vol.3
, pp. 243-252
-
-
Igawa, T.1
Tsunoda, H.2
Kuramochi, T.3
-
160
-
-
84872314093
-
An integrated approach to extreme thermostabilization and affinity maturation of an antibody
-
McConnell AD, Spasojevich V, Macomber JL, et al. An integrated approach to extreme thermostabilization and affinity maturation of an antibody. Protein Eng Des Sel 2011;26:151-164.
-
(2011)
Protein Eng Des Sel
, vol.26
, pp. 151-164
-
-
McConnell, A.D.1
Spasojevich, V.2
Macomber, J.L.3
-
161
-
-
0242363579
-
Generation of a highly stable, internalizing anti-CD22 single-chain Fv fragment for targeting non-Hodgkin's lymphoma
-
Arndt MA, Krauss J, Schwarzenbacher R, et al. Generation of a highly stable, internalizing anti-CD22 single-chain Fv fragment for targeting non-Hodgkin's lymphoma. Int J Cancer 2003;107:822-829.
-
(2003)
Int J Cancer
, vol.107
, pp. 822-829
-
-
Arndt, M.A.1
Krauss, J.2
Schwarzenbacher, R.3
-
162
-
-
77955976111
-
Stability engineering of scFvs for the development of bispecific and multivalent antibodies
-
Miller BR, Demarest SJ, Lugovskoy A, et al. Stability engineering of scFvs for the development of bispecific and multivalent antibodies. Protein Eng Des Sel 2010;23:549-557.
-
(2010)
Protein Eng Des Sel
, vol.23
, pp. 549-557
-
-
Miller, B.R.1
Demarest, S.J.2
Lugovskoy, A.3
-
163
-
-
84873875792
-
Production and binding analyses of a humanised scFv against a cryptic epitope on tumour-associated fibronectin
-
Johdi NA, Harman R, Sanjuan I, et al. Production and binding analyses of a humanised scFv against a cryptic epitope on tumour-associated fibronectin. Protein Expr Purif 2013;88:157-163.
-
(2013)
Protein Expr Purif
, vol.88
, pp. 157-163
-
-
Johdi, N.A.1
Harman, R.2
Sanjuan, I.3
-
164
-
-
84889822148
-
CDR-restricted engineering of native human scFvs creates highly stable and soluble bifunctional antibodies for subcutaneous delivery
-
Fennell BJ, McDonnell B, Tam AS, et al. CDR-restricted engineering of native human scFvs creates highly stable and soluble bifunctional antibodies for subcutaneous delivery. MAbs 2013;5:882-895.
-
(2013)
MAbs
, vol.5
, pp. 882-895
-
-
Fennell, B.J.1
McDonnell, B.2
Tam, A.S.3
-
165
-
-
79951925950
-
Surface supercharged human enteropeptidase light chain shows improved solubility and refolding yield
-
Simeonov P, Berger-Hoffmann R, Hoffmann R, et al. Surface supercharged human enteropeptidase light chain shows improved solubility and refolding yield. Protein Eng Des Sel 2011;24:261-268.
-
(2011)
Protein Eng Des Sel
, vol.24
, pp. 261-268
-
-
Simeonov, P.1
Berger-Hoffmann, R.2
Hoffmann, R.3
-
166
-
-
0031932169
-
Protein aggregation: Folding aggregates, inclusion bodies and amyloid
-
Fink AL. Protein aggregation: folding aggregates, inclusion bodies and amyloid. Fold Des 1998;3:9-23.
-
(1998)
Fold Des
, vol.3
, pp. 9-23
-
-
Fink, A.L.1
-
167
-
-
84860145921
-
Structure-based design of supercharged, highly thermoresistant antibodies
-
Miklos AE, Kluwe C, Der BS. Structure-based design of supercharged, highly thermoresistant antibodies. Chem Biol 2012;19:449-455.
-
(2012)
Chem Biol
, vol.19
, pp. 449-455
-
-
Miklos, A.E.1
Kluwe, C.2
Der, B.S.3
-
168
-
-
62149129236
-
Therapeutic antibodies: Successes, limitations and hopes for the future
-
Chames P, Van RM, Weiss E, Baty D. Therapeutic antibodies: successes, limitations and hopes for the future. Br J Pharmacol 2009;157:220-233.
-
(2009)
Br J Pharmacol
, vol.157
, pp. 220-233
-
-
Chames, P.1
Van, R.M.2
Weiss, E.3
Baty, D.4
-
169
-
-
68949150896
-
Identification of a putative Crf splice variant and generation of recombinant antibodies for the specific detection of Aspergillus fumigatus
-
Schutte M, Thullier P, Pelat T. Identification of a putative Crf splice variant and generation of recombinant antibodies for the specific detection of Aspergillus fumigatus. PLoS One 2009;4:e6625.
-
(2009)
PLoS One
, vol.4
, pp. e6625
-
-
Schutte, M.1
Thullier, P.2
Pelat, T.3
-
170
-
-
62349132009
-
Monoclonal antibodies for cancer immunotherapy
-
Weiner LM, Dhodapkar MV, Ferrone S. Monoclonal antibodies for cancer immunotherapy. Lancet 2009;373:1033-1040.
-
(2009)
Lancet
, vol.373
, pp. 1033-1040
-
-
Weiner, L.M.1
Dhodapkar, M.V.2
Ferrone, S.3
-
171
-
-
27144431943
-
Selecting and screening recombinant antibody libraries
-
Hoogenboom HR. Selecting and screening recombinant antibody libraries. Nat Biotechnol 2005;23:1105-1116.
-
(2005)
Nat Biotechnol
, vol.23
, pp. 1105-1116
-
-
Hoogenboom, H.R.1
-
172
-
-
77954359446
-
Development of human single-chain antibodies to the transferrin receptor that effectively antagonize the growth of leukemias and lymphomas
-
Crepin R, Goenaga AL, Jullienne B. Development of human single-chain antibodies to the transferrin receptor that effectively antagonize the growth of leukemias and lymphomas. Cancer Res 2010;70:5497-5506.
-
(2010)
Cancer Res
, vol.70
, pp. 5497-5506
-
-
Crepin, R.1
Goenaga, A.L.2
Jullienne, B.3
-
173
-
-
77958046455
-
A novel human recombinant single-chain antibody targeting CD166/ALCAM inhibits cancer cell invasion in vitro and in vivo tumour growth
-
Wiiger MT, Gehrken HB, Fodstad O, et al. A novel human recombinant single-chain antibody targeting CD166/ALCAM inhibits cancer cell invasion in vitro and in vivo tumour growth. Cancer Immunol Immunother 2010;59:1665-1674.
-
(2010)
Cancer Immunol Immunother
, vol.59
, pp. 1665-1674
-
-
Wiiger, M.T.1
Gehrken, H.B.2
Fodstad, O.3
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