Structural insights into the evolution of the adaptive immune system

Annual Review of Biophysics

Volumn 42, Issue 1, 2013, Pages 191-215

  Deng, Lu ^a   Luo, Ming ^b,c   Velikovsky, Alejandro ^b,d   Mariuzza, Roy A ^b,d  

^a CENTER FOR BIOLOGICS EVALUATION AND RESEARCH   (United States)

^b UNIVERSITY OF MARYLAND BIOTECHNOLOGY INSTITUTE   (United States)

^c UNIVERSITY OF SCIENCE AND TECHNOLOGY OF CHINA   (China)

^d Bldg 142   (United States)

Author keywords

antibody; immunoglobulin fold; jawless vertebrate; leucine rich repeat; T cell receptor; variable lymphocyte receptor

Indexed keywords

IMMUNOGLOBULIN; LEUCINE RICH REPEAT KINASE 2; LYMPHOCYTE ANTIGEN RECEPTOR; T LYMPHOCYTE RECEPTOR; UNCLASSIFIED DRUG; VARIABLE LYMPHOCYTE RECEPTOR;

ADAPTIVE IMMUNITY; ANTIBODY SPECIFICITY; ANTIGEN BINDING; ANTIGEN RECOGNITION; ARTICLE; BINDING AFFINITY; BINDING SITE; CARBOXY TERMINAL SEQUENCE; CONVERGENT EVOLUTION; HUMAN; IMMUNE RESPONSE; MOLECULAR EVOLUTION; NONHUMAN; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN FOLDING; PROTEIN STRUCTURE; VERTEBRATE;

ADAPTIVE IMMUNITY; ANIMALS; BIOLOGICAL EVOLUTION; LYMPHOCYTES; RECEPTORS, ANTIGEN; RECEPTORS, IMMUNOLOGIC; VERTEBRATES;

EID: 84877724826     PISSN: 1936122X     EISSN: 19361238     Source Type: Book Series    
DOI: 10.1146/annurev-biophys-083012-130422     Document Type: Article

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