-
1
-
-
0025978976
-
Man-made antibodies
-
Winter, G. and Milstein, C. 1991. Man-made antibodies. Nature 349:293-9.
-
(1991)
Nature
, vol.349
, pp. 293-299
-
-
Winter, G.1
Milstein, C.2
-
2
-
-
0022558297
-
Replacing the complementarity-determining regions in a human antibody with those from a mouse
-
Jones, P. T., Dear, P. H., Foote, J., Neuberger, M. S. and Winter, G. 1986. Replacing the complementarity-determining regions in a human antibody with those from a mouse. Nature 321:522-5.
-
(1986)
Nature
, vol.321
, pp. 522-525
-
-
Jones, P.T.1
Dear, P.H.2
Foote, J.3
Neuberger, M.S.4
Winter, G.5
-
3
-
-
0023911111
-
Reshaping human antibodies for therapy
-
Riechmann, L., Clark, M., Waldmann, H. and Winter, G. 1988. Reshaping human antibodies for therapy. Nature 332:323-7.
-
(1988)
Nature
, vol.332
, pp. 323-327
-
-
Riechmann, L.1
Clark, M.2
Waldmann, H.3
Winter, G.4
-
4
-
-
0026783632
-
Humanised monoclonal antibody therapy for rheumatoid arthritis
-
Isaacs, J., Watts, R. A., Hazleman, B. L, Hale, G., Keogan, M. T, Cobbold, S. P. and Waldmann, H. 1992. Humanised monoclonal antibody therapy for rheumatoid arthritis, Lancet 26:748-752.
-
(1992)
Lancet
, vol.26
, pp. 748-752
-
-
Isaacs, J.1
Watts, R.A.2
Hazleman, B.L.3
Hale, G.4
Keogan, M.T.5
Cobbold, S.P.6
Waldmann, H.7
-
5
-
-
0025226085
-
Phage antibodies: Filamentous phage displaying antibody variable domains
-
McCafferty, J., Griffiths, A. D., Winter, G. and Chiswell, D. J. 1990. Phage antibodies: filamentous phage displaying antibody variable domains. Nature 348:552-4.
-
(1990)
Nature
, vol.348
, pp. 552-554
-
-
McCafferty, J.1
Griffiths, A.D.2
Winter, G.3
Chiswell, D.J.4
-
7
-
-
0027962758
-
Making antibodies by phage display technology
-
Winter, G., Griffiths, A. D., Hawkins, R. E. and Hoogenboom, H. R. 1994. Making antibodies by phage display technology. Annu. Rev. Immunol. 12:433-455.
-
(1994)
Annu. Rev. Immunol
, vol.12
, pp. 433-455
-
-
Winter, G.1
Griffiths, A.D.2
Hawkins, R.E.3
Hoogenboom, H.R.4
-
8
-
-
0026317443
-
By-passing immunization: Human antibodies from V-gene libraries displayed on phage
-
Marks, J. D., et al. 1991. By-passing immunization: Human antibodies from V-gene libraries displayed on phage. J. Mol. Biol. 222:581-597.
-
(1991)
J. Mol. Biol
, vol.222
, pp. 581-597
-
-
Marks, J.D.1
-
9
-
-
0027473684
-
Human anti-self antibodies with high specificity from phage display libraries
-
Griffiths, A. D., et al. 1993. Human anti-self antibodies with high specificity from phage display libraries. EMBOJ. 12:725-734.
-
(1993)
EMBOJ
, vol.12
, pp. 725-734
-
-
Griffiths, A.D.1
-
10
-
-
0018567632
-
Theoretical studies of clonal selection: Minimial antibody repertoire size and reliability of self non-self discrimination
-
Perelson, A. S. and Oster, G. F. 1979. Theoretical studies of clonal selection: Minimial antibody repertoire size and reliability of self non-self discrimination. J. Theor. Biol. 81:645-670.
-
(1979)
J. Theor. Biol
, vol.81
, pp. 645-670
-
-
Perelson, A.S.1
Oster, G.F.2
-
11
-
-
0028926814
-
Selection and application of human single chain Fv antibody fragments from a semi-synthetic phage antibody display library with designed CDR3 regions
-
de Kruif, J., Boel, E. and Logtenberg, T. 1995. Selection and application of human single chain Fv antibody fragments from a semi-synthetic phage antibody display library with designed CDR3 regions. J. Mol. Biol. 248:97-105.
-
(1995)
J. Mol. Biol
, vol.248
, pp. 97-105
-
-
De Kruif, J.1
Boel, E.2
Logtenberg, T.3
-
12
-
-
14744300211
-
By-passing immunization: Building high affinity human antibodies by chain shuffling
-
Marks, J. D., et al. 1992. By-passing immunization: building high affinity human antibodies by chain shuffling. Bio/Technology 10:779-783.
-
(1992)
Bio/Technology
, vol.10
, pp. 779-783
-
-
Marks, J.D.1
-
13
-
-
0026589089
-
Original and artificial antibodies
-
Gherardi, E. and Milstein, C. 1992. Original and artificial antibodies. Nature 357:201-202.
-
(1992)
Nature
, vol.357
, pp. 201-202
-
-
Gherardi, E.1
Milstein, C.2
-
14
-
-
0027175018
-
Combinatorial infection and in vivo recombination: A strategy for making large phage antibody repertoires
-
Waterhouse, P., Griffiths, A. D., Johnson, K. S. and Winter, G. 1993. Combinatorial infection and in vivo recombination: a strategy for making large phage antibody repertoires. Nucleic Acids Research 21:2265-66.
-
(1993)
Nucleic Acids Research
, vol.21
, pp. 2265-2266
-
-
Waterhouse, P.1
Griffiths, A.D.2
Johnson, K.S.3
Winter, G.4
-
15
-
-
0028291823
-
Isolation of high affinity human antibodies directly from large synthetic repertoires
-
Griffiths, A. D., et al. 1994. Isolation of high affinity human antibodies directly from large synthetic repertoires. EMBO J. 13:3245-3260.
-
(1994)
EMBO J
, vol.13
, pp. 3245-3260
-
-
Griffiths, A.D.1
-
16
-
-
0026785856
-
The repertoire of human germline VH sequences reveals about fifty groups of VH segments with different hypervariable loops
-
Tomlinson, I. M., Walter, G., Marks, J. D., Uewelyn, M. B. and Winter, G. 1992. The repertoire of human germline VH sequences reveals about fifty groups of VH segments with different hypervariable loops. J. Mol. Biol. 227:776-798.
-
(1992)
J. Mol. Biol
, vol.227
, pp. 776-798
-
-
Tomlinson, I.M.1
Walter, G.2
Marks, J.D.3
Uewelyn, M.B.4
Winter, G.5
-
17
-
-
0028326520
-
A directory of human germline Vk segments reveals a strong bias in their usage
-
Cox, J. P. L., Tomlinson, I. M. and Winter, G. 1994. A directory of human germline Vk segments reveals a strong bias in their usage. Eur. J. Immunol. 24:827-836.
-
(1994)
Eur. J. Immunol
, vol.24
, pp. 827-836
-
-
Cox, J.P.L.1
Tomlinson, I.M.2
Winter, G.3
-
18
-
-
0027201551
-
Cloning and sequencing of human immunoglobulin VI segments
-
Williams, S. C. and Winter, G. 1993. Cloning and sequencing of human immunoglobulin VI segments. Eur. J. Immunol. 23:1456-61.
-
(1993)
Eur. J. Immunol
, vol.23
, pp. 1456-1461
-
-
Williams, S.C.1
Winter, G.2
-
19
-
-
0025835310
-
Making antibody fragments using phage display libraries
-
Clackson, T., Hoogenboom, H. R., Griffiths, A. D. and Winter, G. 1991. Making antibody fragments using phage display libraries. Mature 352:624-628.
-
(1991)
Mature
, vol.352
, pp. 624-628
-
-
Clackson, T.1
Hoogenboom, H.R.2
Griffiths, A.D.3
Winter, G.4
-
20
-
-
0027453997
-
Preferential use of a H chain V region in antitumour-associated glycoprotein-72 monoclonal antibodies
-
Rixon, M. W., Gourlie, B. B., Kaplan, D. A., Schlom, J. and S., M. P. 1993. Preferential use of a H chain V region in antitumour-associated glycoprotein-72 monoclonal antibodies. The Journal of Immunology 151:6559-6568.
-
(1993)
The Journal of Immunology
, vol.151
, pp. 6559-6568
-
-
Rixon, M.W.1
Gourlie, B.B.2
Kaplan, D.A.3
Schlom, J.4
-
21
-
-
0028826624
-
An antibody fragment from a phage display library competes for ligand binding to the low density lipoprotein receptor family and inhibits rhinovirus infection
-
Hodits, R. A., et al. 1995. An antibody fragment from a phage display library competes for ligand binding to the low density lipoprotein receptor family and inhibits rhinovirus infection. The Journal of Biological Chemistry 270:24078-24085.
-
(1995)
The Journal of Biological Chemistry
, vol.270
, pp. 24078-24085
-
-
Hodits, R.A.1
-
22
-
-
0025856601
-
Kinetic maturation of an immune response
-
Foote, J. and Milstein C. 1991. Kinetic maturation of an immune response. Wafure 352:530-532.
-
(1991)
Wafure
, vol.352
, pp. 530-532
-
-
Foote, J.1
Milstein, C.2
-
23
-
-
0026699293
-
Selection of phage antibodies by binding affinity: Mimicking affinity maturation
-
Hawkins, R. E., Russell, S. J. and Winter, G. 1992. Selection of phage antibodies by binding affinity: mimicking affinity maturation. J. Mol. Biol. 226:889-896.
-
(1992)
J. Mol. Biol
, vol.226
, pp. 889-896
-
-
Hawkins, R.E.1
Russell, S.J.2
Winter, G.3
-
24
-
-
0026535931
-
In vitro selection and affinity maturation of antibodies from a naive combinatorial immunoglobulin library
-
Gram, H., et al. 1992. In vitro selection and affinity maturation of antibodies from a naive combinatorial immunoglobulin library. Proc. Natl. Acad. Sci. USA 89:3576-3580.
-
(1992)
Proc. Natl. Acad. Sci. USA
, vol.89
, pp. 3576-3580
-
-
Gram, H.1
-
25
-
-
0027420237
-
Medical applications of single-chain antibodies
-
Huston, J. S., et al. 1993. Medical applications of single-chain antibodies. Intern. Rev. Immunol. 10:195-217.
-
(1993)
Intern. Rev. Immunol
, vol.10
, pp. 195-217
-
-
Huston, J.S.1
-
26
-
-
0022998204
-
Linkage of low and high affinity anti-fluorescein idiotype families
-
Bedzyk, W. D., Reinitz, D. M. and Voss, E. W. 1986. Linkage of low and high affinity anti-fluorescein idiotype families. Molec. Immunol. 23:1319-1328.
-
(1986)
Molec. Immunol
, vol.23
, pp. 1319-1328
-
-
Bedzyk, W.D.1
Reinitz, D.M.2
Voss, E.W.3
-
27
-
-
0027982861
-
Localisation of monoclonal antibodies reacting with different epitopes on carcinoembryonic antigen (CEA)—implications for targeted therapy
-
Boxer, G. M., Abassi, A. M., Pedley, R. B. and Begent R. H. 1994. Localisation of monoclonal antibodies reacting with different epitopes on carcinoembryonic antigen (CEA)—implications for targeted therapy. Brit. J. Cancer 69:307-314.
-
(1994)
Brit. J. Cancer
, vol.69
, pp. 307-314
-
-
Boxer, G.M.1
Abassi, A.M.2
Pedley, R.B.3
Begent, R.H.4
-
28
-
-
0028078866
-
Phage libraries for generation of clinically useful antibodies
-
Chester, K. A., Begent, R. H., Robson, L, Keep, P., Pedley, R. B., et al. 1994. Phage libraries for generation of clinically useful antibodies. Lancet 343:455-456.
-
(1994)
Lancet
, vol.343
, pp. 455-456
-
-
Chester, K.A.1
Begent, R.H.2
Robson, L.3
Keep, P.4
Pedley, R.B.5
-
29
-
-
0029653368
-
Kinetic and affinity limits on antibodies produced during immune responses
-
Foote, J. and Eisen, H. N. 1995. Kinetic and affinity limits on antibodies produced during immune responses. Proc. Natl. Acad. Sci. USA 92:1254-1256.
-
(1995)
Proc. Natl. Acad. Sci. USA
, vol.92
, pp. 1254-1256
-
-
Foote, J.1
Eisen, H.N.2
-
30
-
-
0019888656
-
Monoclonal antibodies to the low density lipoprotein receptor as probes for study of receptor mediated endocytosis and the genetics of familial hypercholesterolemia
-
Beisiegel, U., Schneider, W. J., Goldstein, J. L, Anderson, R. G. and Brown, M. S. 1981. Monoclonal antibodies to the low density lipoprotein receptor as probes for study of receptor mediated endocytosis and the genetics of familial hypercholesterolemia. J. Biol. Chem. 256:11923-11931.
-
(1981)
J. Biol. Chem
, vol.256
, pp. 11923-11931
-
-
Beisiegel, U.1
Schneider, W.J.2
Goldstein, J.L.3
Erson, R.G.4
Brown, M.S.5
-
31
-
-
0026519867
-
Cell selection strategies for making anytibod-ies from variable gene libraries: Trapping the memory pool
-
Hawkins, R. E. and Winter, G. 1992. Cell selection strategies for making anytibod-ies from variable gene libraries: trapping the memory pool. Eur. J. Immunol. 22:867-870.
-
(1992)
Eur. J. Immunol
, vol.22
, pp. 867-870
-
-
Hawkins, R.E.1
Winter, G.2
-
32
-
-
0026655937
-
Recombinant human Fab fragments neutralize type I immunodefficiency virus in vitro
-
Barbas, C. F, Bjorling, E., Chiodi, R, Dunlop, N., Cabara, D., et al. 1992. Recombinant human Fab fragments neutralize type I immunodefficiency virus in vitro. Proc. Natl. Acad. Sci. USA 89:9339-9343.
-
(1992)
Proc. Natl. Acad. Sci. USA
, vol.89
, pp. 9339-9343
-
-
Barbas, C.F.1
Bjorling, E.2
Chiodi, R.3
Dunlop, N.4
Cabara, D.5
-
33
-
-
0027223565
-
Molecular profile of an antibody response to HIV-1 as probed by combinatorial libraries
-
Barbas, C. R, Collet, T. A., Amberg, W., Roben, P., Binley, J. M., et al. 1993. Molecular profile of an antibody response to HIV-1 as probed by combinatorial libraries. J. Mol. Biol. 230:812-823.
-
(1993)
J. Mol. Biol
, vol.230
, pp. 812-823
-
-
Barbas, C.R.1
Collet, T.A.2
Amberg, W.3
Roben, P.4
Binley, J.M.5
-
34
-
-
0026486724
-
Human monoclonal Fab fragments derived from a combinatorial library bind to respiratory syncytial virus F glycoprotein and neutralise infectivity
-
Barbas, C. F., Crowe, J. E., Cabab, D., Jones, T. M., Zebedee, S. L., et al. 1992. Human monoclonal Fab fragments derived from a combinatorial library bind to respiratory syncytial virus F glycoprotein and neutralise infectivity. Proc. Natl. Acad. Sci. USA 89:10164-10168.
-
(1992)
Proc. Natl. Acad. Sci. USA
, vol.89
, pp. 10164-10168
-
-
Barbas, C.F.1
Crowe, J.E.2
Cabab, D.3
Jones, T.M.4
Zebedee, S.L.5
-
35
-
-
0027285847
-
Human monoclonal antibodies against a plethora of viral pathogens from single combinatorial libraries
-
Williamson, R. A., Burioni, R., Sanna, P. P. and Partridge, L. J. 1993. Human monoclonal antibodies against a plethora of viral pathogens from single combinatorial libraries. Proc. Natl. Acad. Sci. USA 90:4141-4145.
-
(1993)
Proc. Natl. Acad. Sci. USA
, vol.90
, pp. 4141-4145
-
-
Williamson, R.A.1
Burioni, R.2
Sanna, P.P.3
Partridge, L.J.4
-
36
-
-
0028433465
-
Selection and rapid purification of murine antibody fragments that bind a transition-state analog by phage display
-
McCafferty, J., et al. 1994. Selection and rapid purification of murine antibody fragments that bind a transition-state analog by phage display. Appl. Biochem. Biotech. 47:157-173.
-
(1994)
Appl. Biochem. Biotech
, vol.47
, pp. 157-173
-
-
McCafferty, J.1
-
37
-
-
0004198722
-
Protein engineering of antibody binding sites: Recovery of specific activity in an anti-digoxin single-chain Fv analogue produced in Escherichia coli
-
Huston, J. S., et al. 1988. Protein engineering of antibody binding sites: recovery of specific activity in an anti-digoxin single-chain Fv analogue produced in Escherichia coli. Proc. Natl. Acad. Sci. USA 85:5879-83.
-
(1988)
Proc. Natl. Acad. Sci. USA
, vol.85
, pp. 5879-5883
-
-
Huston, J.S.1
-
38
-
-
0023052239
-
An hsp70-like protein in the ER: Identity with the 78kd glucose-regulated protein and immunoglobulin heavy chain binding protein
-
Munro, S. and Pelham, H. R. B. 1986. An hsp70-like protein in the ER: identity with the 78kd glucose-regulated protein and immunoglobulin heavy chain binding protein. Cell 46:291-300.
-
(1986)
Cell
, vol.46
, pp. 291-300
-
-
Munro, S.1
Pelham, H.R.B.2
-
39
-
-
0021964141
-
Measurements of the true affinity constant in solution of antigen-antibody complexes by enzyme-linked immunosorbent assay
-
Friguet, B., Chaffotte, A. R, Djavadi-Ohaniance, L. and Goldberg, M. E. 1985. Measurements of the true affinity constant in solution of antigen-antibody complexes by enzyme-linked immunosorbent assay. J. Immunol. Methods 77:305-319.
-
(1985)
J. Immunol. Methods
, vol.77
, pp. 305-319
-
-
Friguet, B.1
Chaffotte, A.R.2
Djavadi-Ohaniance, L.3
Goldberg, M.E.4
-
40
-
-
0027298141
-
Methods for measurement of antibody/antigen affinity based on ELISA and RIA
-
Goldberg, M. E. and Djavadi-Ohaniance, L. 1993. Methods for measurement of antibody/antigen affinity based on ELISA and RIA. Curr. Op. Immunol. 5:278-281.
-
(1993)
Curr. Op. Immunol
, vol.5
, pp. 278-281
-
-
Goldberg, M.E.1
Djavadi-Ohaniance, L.2
-
41
-
-
0028235295
-
A map of the human immunoglobulin VH locus completed by analysis of the telomeric region of chromosome 14q
-
Cook, G. P., et al. 1994. A map of the human immunoglobulin VH locus completed by analysis of the telomeric region of chromosome 14q. Nature Genet. 7:162-168.
-
(1994)
Nature Genet
, vol.7
, pp. 162-168
-
-
Cook, G.P.1
-
42
-
-
0028180225
-
Human immunoglobulin VH and D segments on chromosomes 15q11.2 and 16p11.2
-
Tomlinson, I. M., et al. 1994. Human immunoglobulin VH and D segments on chromosomes 15q11.2 and 16p11.2. Human Molec. Genet. 3:853-860.
-
(1994)
Human Molec. Genet
, vol.3
, pp. 853-860
-
-
Tomlinson, I.M.1
-
43
-
-
0004032583
-
-
U.S. Department of Health and Human Services
-
Kabat, E. A., Wu, T. T, Perry, H. M., Gottesman, K. S. and Foeller, C. Sequences of proteins of immunological interest (U.S. Department of Health and Human Services, 1991).
-
(1991)
Sequences of Proteins of Immunological Interest
-
-
Kabat, E.A.1
Wu, T.T.2
Perry, H.M.3
Gottesman, K.S.4
Foeller, C.5
-
44
-
-
0025348829
-
Definition of the human immunoglobulin variable lambda (IGLV) gene subgroups
-
Chuchana, P., et al. 1990. Definition of the human immunoglobulin variable lambda (IGLV) gene subgroups. Eur. J. Immunol. 20:1317-25.
-
(1990)
Eur. J. Immunol
, vol.20
, pp. 1317-1325
-
-
Chuchana, P.1
|