APE1/Ref-1 as an emerging therapeutic target for various human diseases: Phytochemical modulation of its functions

Experimental and Molecular Medicine

Volumn 46, Issue 7, 2014, Pages

  Thakur, Shweta ^a   Sarkar, Bibekananda ^a   Cholia, Ravi P ^a   Gautam, Nandini ^a   Dhiman, Monisha ^a   Mantha, Anil K ^a,b  

^a CENTRAL UNIVERSITY OF PUNJAB   (India)

^b University of Texas Medical Branch School of Medicine   (United States)

Author keywords

Alzheimer's disease; APE1 Ref 1; Base excision repair; Cancer therapeutics; Neurodegenerative diseases; Phytochemicals

Indexed keywords

ANGELICA GIGANS EXTRACT; CATALASE; CURCUMIN; DACARBAZINE; DNA; DNA (APURINIC OR APYRIMIDINIC SITE) LYASE; EPIGALLOCATECHIN GALLATE; HYPOXIA INDUCIBLE FACTOR 1ALPHA; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; ISOFLAVONE; LUTEOLIN; PLANT EXTRACT; POLYPHENOL; PROTEIN P53; QUERCETIN; REACTIVE NITROGEN SPECIES; REACTIVE OXYGEN METABOLITE; REDOX EFFECTOR FACTOR 1; RESVERATROL; ROSMARINIC ACID; SMALL INTERFERING RNA; SUPEROXIDE DISMUTASE; THIOREDOXIN; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR PAX8; UNCLASSIFIED DRUG; APEX1 PROTEIN, HUMAN; PLANT MEDICINAL PRODUCT;

AMYOTROPHIC LATERAL SCLEROSIS; ANGIOGENESIS; ANTIINFLAMMATORY ACTIVITY; ANTIOXIDANT ACTIVITY; APOPTOSIS; CELL SURVIVAL; CELLULAR DISTRIBUTION; DNA DAMAGE; DNA REPAIR; ENERGY METABOLISM; EXCISION REPAIR; HUMAN; HUNTINGTON CHOREA; INFLAMMATION; MOUSE; NERVE DEGENERATION; NONHUMAN; OXIDATIVE STRESS; PROTEIN FUNCTION; PROTEIN INTERACTION; PROTEIN PROTEIN INTERACTION; REVIEW; ANIMAL; GENETIC POLYMORPHISM; GENETICS; METABOLISM; MOLECULARLY TARGETED THERAPY; NEOPLASMS; NEURODEGENERATIVE DISEASES; PROCEDURES;

ANIMALS; DNA DAMAGE; DNA REPAIR; DNA-(APURINIC OR APYRIMIDINIC SITE) LYASE; HUMANS; MOLECULAR TARGETED THERAPY; NEOPLASMS; NEURODEGENERATIVE DISEASES; OXIDATIVE STRESS; PHYTOCHEMICALS; POLYMORPHISM, GENETIC; PROTEIN INTERACTION MAPS;

EID: 84905239621     PISSN: 12263613     EISSN: 20926413     Source Type: Journal    
DOI: 10.1038/emm.2014.42     Document Type: Review

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