DNA base-excision repair enzyme apurinic/apyrimidinic endonuclease/redox factor-1 is increased and competent in the brain and spinal cord of individuals with amyotrophic lateral sclerosis

NeuroMolecular Medicine

Volumn 2, Issue 1, 2002, Pages 47-60

  Shaikh, Arif Y ^a   Martin, Lee J ^a  

^a JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Apoptosis; DNA damage; DNA repair; DNA single strand breaks; Lou Gehrig's disease; Motor neuron; Programmed cell death

Indexed keywords

DNA; DNA (APURINIC OR APYRIMIDINIC SITE) LYASE; OXIDOREDUCTASE; PLASMID DNA; PROTEIN P53; REDOX EFFECTOR FACTOR 1; REGULATOR PROTEIN; SINGLE STRANDED DNA; TRANSCRIPTION FACTOR; UNCLASSIFIED DRUG; APEX1 PROTEIN, HUMAN; APURINIC ACID; LYASE; NERVE PROTEIN;

ADULT; AGED; AMYOTROPHIC LATERAL SCLEROSIS; ARTICLE; ASTROCYTE; BINDING SITE; BRAIN CELL; CELL DEATH; CELL DEGENERATION; CELL DENSITY; CENTRAL NERVOUS SYSTEM DISEASE; CLINICAL ARTICLE; CONTROLLED STUDY; DNA REPAIR; ENZYME ANALYSIS; EXCISION REPAIR; FEMALE; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOBLOTTING; IMMUNOCYTOCHEMISTRY; MALE; MOTONEURON; OXIDATION REDUCTION REACTION; PRIORITY JOURNAL; PROTEIN LOCALIZATION; SINGLE CELL DENSITOMETRY; SPINAL CORD; STATISTICAL SIGNIFICANCE; TRANSCRIPTION REGULATION; WHITE MATTER; APOPTOSIS; BIOSYNTHESIS; BRAIN; CELL NUCLEUS; COMPARATIVE STUDY; DNA DAMAGE; ENZYME INDUCTION; ENZYMOLOGY; GENETICS; METABOLISM; MIDDLE AGED; MOTOR CORTEX; MOTOR NEURON DISEASE; OXIDATIVE STRESS; PATHOLOGY; ULTRASTRUCTURE;

ALOCASIA MACRORRHIZOS;

AGED; APOPTOSIS; APURINIC ACID; ASTROCYTES; BRAIN; CARBON-OXYGEN LYASES; CELL NUCLEUS; DNA DAMAGE; DNA REPAIR; DNA-(APURINIC OR APYRIMIDINIC SITE) LYASE; ENZYME INDUCTION; FEMALE; HUMANS; MALE; MIDDLE AGED; MOTOR CORTEX; MOTOR NEURON DISEASE; MOTOR NEURONS; NERVE TISSUE PROTEINS; OXIDATIVE STRESS; SPINAL CORD;

EID: 0036357310     PISSN: 15351084     EISSN: None     Source Type: Journal    
DOI: 10.1385/NMM:2:1:47     Document Type: Article

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