p53-Induced Up-Regulation of MnSOD and GPx but not Catalase Increases Oxidative Stress and Apoptosis

Cancer Research

Volumn 64, Issue 7, 2004, Pages 2350-2356

  Hussain, S Perwez ^a   Amstad, Paul ^a,b   He, Peijun ^a   Robles, Ana ^a   Lupold, Shawn ^a,c   Kaneko, Ichiro ^a,d   Ichimiya, Masato ^a,e   Sengupta, Sagar ^a   Mechanic, Leah ^a   Okamura, Shu ^a   Hofseth, Lorne J ^a   Moake, Matthew ^a   Nagashima, Makoto ^a   Forrester, Kathleen S ^a   Harris, Curtis C ^a  

^a NATIONAL CANCER INSTITUTE   (United States)

^b NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES   (United States)

^c JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^d UNIVERSITY OF TOKYO   (Japan)

^e Kobe Teishin Hospital   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

ACETYLCYSTEINE; ANTIOXIDANT; CALCIUM ION; CATALASE; CYTOCHROME C; DOXORUBICIN; GLUTATHIONE PEROXIDASE; MANGANESE SUPEROXIDE DISMUTASE; MUTANT PROTEIN; PROTEIN P53; PROTEIN TK6; PROTEIN WTK1; REACTIVE OXYGEN METABOLITE; TETRACYCLINE; UNCLASSIFIED DRUG;

APOPTOSIS; ARTICLE; CHROMOSOME ABERRATION; CONTROLLED STUDY; DNA MICROARRAY; DNA STRAND BREAKAGE; ENZYME ACTIVITY; FAMILIAL CANCER; FIBROBLAST; HUMAN; HUMAN CELL; OXIDATION REDUCTION REACTION; OXIDATIVE STRESS; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN EXPRESSION; RECEPTOR UPREGULATION; WILD TYPE;

APOPTOSIS; CALCIUM; CATALASE; CELL LINE; CYTOCHROMES C; DOXORUBICIN; ENZYME INDUCTION; FIBROBLASTS; GENE EXPRESSION REGULATION, ENZYMOLOGIC; GLUTATHIONE PEROXIDASE; HUMANS; MITOCHONDRIA; OXIDATIVE STRESS; REACTIVE OXYGEN SPECIES; RNA, MESSENGER; SUPEROXIDE DISMUTASE; TUMOR SUPPRESSOR PROTEIN P53; UP-REGULATION;

EID: 11144356558     PISSN: 00085472     EISSN: None     Source Type: Journal    
DOI: 10.1158/0008-5472.CAN-2287-2     Document Type: Article

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