HIF-1α, STAT3, CBP/p300 and Ref-1/APE are components of a transcriptional complex that regulates Src-dependent hypoxia-induced expression of VEGF in pancreatic and prostate carcinomas

Oncogene

Volumn 24, Issue 19, 2005, Pages 3110-3120

  Gray, Michael J ^a   Zhang, Jing ^a,b   Ellis, Lee M ^a   Semenza, Gregg L ^c   Evans, Douglas B ^a   Watowich, Stephanie S ^a   Gallick, Gary E ^a,b  

^a UNIVERSITY OF TEXAS MD ANDERSON CANCER CENTER   (United States)

^b UNIVERSITY OF TEXAS   (United States)

^c JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Angiogenesis; HIF 1 VEGF; Hypoxia; Src; STAT3

Indexed keywords

COBALT CHLORIDE; HISTONE ACETYLTRANSFERASE PCAF; HYPOXIA INDUCIBLE FACTOR 1ALPHA; MESSENGER RNA; PROTEIN TYROSINE KINASE; REDOX EFFECTOR FACTOR 1; STAT3 PROTEIN; VASCULOTROPIN; APEX1 PROTEIN, HUMAN; COBALT; DNA (APURINIC OR APYRIMIDINIC SITE) LYASE; DNA BINDING PROTEIN; HIF1A PROTEIN, HUMAN; LUCIFERASE; NUCLEAR PROTEIN; STAT3 PROTEIN, HUMAN; TRANSACTIVATOR PROTEIN; TRANSCRIPTION FACTOR; VASCULOTROPIN A;

ARTICLE; CANCER CELL; CARCINOMA CELL; CELL SURVIVAL; COMPLEX FORMATION; CONTROLLED STUDY; ENZYME ACTIVATION; FIBROBLAST; HUMAN; HUMAN CELL; HYPOXIA; MALE; MUTANT; PANCREAS CARCINOMA; PRIORITY JOURNAL; PROMOTER REGION; PROSTATE CARCINOMA; PROTEIN DNA BINDING; PROTEIN PHOSPHORYLATION; PROTEIN PROTEIN INTERACTION; REGULATORY MECHANISM; RNA TRANSCRIPTION; STEADY STATE; TRANSCRIPTION INITIATION; ANOXIA; AUTORADIOGRAPHY; BIOSYNTHESIS; CHROMATIN IMMUNOPRECIPITATION; ENZYME LINKED IMMUNOSORBENT ASSAY; FEMALE; FLUORESCENCE MICROSCOPY; GENE EXPRESSION REGULATION; GENETIC TRANSCRIPTION; IMMUNOBLOTTING; IMMUNOPRECIPITATION; METABOLISM; METASTASIS; NEOPLASM; NEOVASCULARIZATION (PATHOLOGY); PANCREAS TUMOR; PHOSPHORYLATION; PROSTATE TUMOR; PROTEIN BINDING; SIGNAL TRANSDUCTION; TUMOR CELL LINE;

ANOXIA; AUTORADIOGRAPHY; CELL LINE, TUMOR; CHROMATIN IMMUNOPRECIPITATION; COBALT; DNA-(APURINIC OR APYRIMIDINIC SITE) LYASE; DNA-BINDING PROTEINS; ENZYME ACTIVATION; ENZYME-LINKED IMMUNOSORBENT ASSAY; FEMALE; FIBROBLASTS; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; HYPOXIA-INDUCIBLE FACTOR 1, ALPHA SUBUNIT; IMMUNOBLOTTING; IMMUNOPRECIPITATION; LUCIFERASES; MALE; MICROSCOPY, FLUORESCENCE; NEOPLASM METASTASIS; NEOPLASMS; NEOVASCULARIZATION, PATHOLOGIC; NUCLEAR PROTEINS; PANCREATIC NEOPLASMS; PHOSPHORYLATION; PROMOTER REGIONS (GENETICS); PROSTATIC NEOPLASMS; PROTEIN BINDING; RNA, MESSENGER; SIGNAL TRANSDUCTION; SRC-FAMILY KINASES; STAT3 TRANSCRIPTION FACTOR; TRANS-ACTIVATORS; TRANSCRIPTION FACTORS; TRANSCRIPTION, GENETIC; VASCULAR ENDOTHELIAL GROWTH FACTOR A;

EID: 18844444774     PISSN: 09509232     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.onc.1208513     Document Type: Article

References (81)

1. Abraham SE, Lobo S, Yaciuk P, Wang HG and Moran E. (1993). Oncogene, 8, 1639-1647.
2. Alvarez-Tejado M, Naranjo-Suarez S, Jimenez C, Carrera AC, Landazuri MO and del Peso L. (2001). J. Biol. Chem., 276, 22368-22374.
3. Arany Z, Huang LE, Eckner R, Bhattacharya S, Jiang C, Goldberg MA, Bunn HF and Livingston DM. (1996). Proc. Natl. Acad. Sci. USA, 93, 12969-12973.
4. Bardos JI and Ashcroft M. (2004). BioEssays, 26, 262-269.
5. Bromberg J and Darnell Jr JE. (2000). Oncogene, 19, 2468-2473.
6. Bromberg JF, Horvath CM, Besser D, Lathem WW and Darnell Jr JE. (1998). Mol. Cell. Biol., 18, 2553-2558.
7. Buchler P, Reber HA, Buchler M, Shrinkante S, Buchler MW, Friess H, Semenza GL and Hines OJ. (2003). Pancreas, 26, 56-64.
8. Calo V, Migliavacca M, Bazan V, Macaluso M, Buscemi M, Gebbia N and Russo A. (2003). J. Cell Physiol., 197, 157-168.
9. Cao X, Tay A, Guy G and Tan Y. (1996). Mol. Cell. Biol., 16, 1595-1603.
10. Carrero P, Okamoto K, Coumailleau P, O'Brien S, Tanaka H and Poellinger L. (2000). Mol. Cell. Biol., 20, 402-415.
11. Chan DA, Sutphin PD, Denko NC and Giaccia AJ. (2002). J. Biol. Chem., 277, 40112-40117.
12. Ebert BL and Bunn HF. (1998). Mol. Cell. Biol., 18, 4089-4096.
13. Eliceiri BP, Paul R, Schwartzberg PL, Hood JD, Leng J and Cheresh DA. (1999). Mol. Cell., 4, 915-924.
14. Ellis LM and Fidler IJ. (1996). Eur. J. Cancer, 32A, 2451-2460.
15. Ellis LM, Staley CA, Liu W, Fleming RY, Parikh NU, Bucana CD and Gallick GE. (1998). J. Biol. Chem., 273, 1052-1057.
16. Firth JD, Ebert BL and Ratcliffe PJ. (1995). J. Biol. Chem., 270, 21021-21027.
17. Fleming RY, Ellis LM, Parikh NU, Liu W, Staley CA and Gallick GE. (1997). Surgery, 122, 501-507.
18. Folkman J. (1992). Semin. Cancer Biol., 3, 65-71.
19. Folkman J. (2002). Semin. Oncol., 29, 15-18.
20. Fontanini G, Faviana P, Lucchi M, Boldrini L, Mussi A, Camacci T, Mariani MA, Angeletti CA, Basolo F and Pingitore R. (2002). Br. J. Cancer, 86, 558-563.
21. Forsythe JA, Jiang BH, Iyer NV, Agani F, Leung SW, Koos RD and Semenza GL. (1996). Mol. Cell. Biol., 16, 4604-4613.
22. Gu J, Milligan J and Huang LE. (2001). J. Biol. Chem., 276, 3550-3554.
23. Guo D, Jia Q, Song HY, Warren RS and Donner DB. (1995). J. Biol. Chem., 270, 6729-6733.
24. Harris AL. (2002). Nat. Rev. Cancer, 2, 38-47.
25. Hartenbach EM, Olson TA, Goswitz JJ, Mohanraj D, Twiggs LB, Carson LF and Ramakrishnan S. (1997). Cancer Lett., 121, 169-175.
26. Iliopoulos O, Levy AP, Jiang C, Kaelin Jr WG and Goldberg MA. (1996). Proc. Natl. Acad Sci. USA, 93, 10595-10599.
27. Ishigami SI, Arii S, Furutani M, Niwano M, Harada T, Mizumoto M, Mori A, Onodera H and Imamura M. (1998). Br. J. Cancer, 78, 1379-1384.
28. Itakura J, Ishiwata T, Friess H, Fujii H, Matsumoto Y, Buchler MW and Korc M. (1997). Clin. Cancer Res., 3, 1309-1316.
29. Ivan M, Kondo K, Yang H, Kim W, Valiando J, Ohh M, Salic A, Asara JM, Lane WS and Kaelin Jr WG. (2001). Science, 292, 464-468.
30. Jackson MW, Bentel JM and Tilley WD. (1997). J. Urol., 157, 2323-2328.
31. Jiang BH, Agani F, Passaniti A and Semenza GL. (1997). Cancer Res., 57, 5328-5335.
32. Jiang BH, Rue E, Wang GL, Roe R and Semenza GL. (1996). J. Biol. Chem., 271, 17771-17778.
33. Joung YH, Park JH, Park T, Lee CS, Kim OH, Ye SK. Yang UM, Lee KJ and Yang YM. (2003). Exp. Mol. Med., 35, 350-357.
34. Kallio PJ, Okamoto K, O'Brien S, Carrero P, Makino Y, Tanaka H and Poellinger L. (1998). EMBO J., 17, 6573-6586.
35. Kaptein A, Paillard V and Saunders M. (1996). J. Biol. Chem., 271, 5961-5964.
36. Karni R, Dor Y, Keshet E, Meyuhas O and Levitzki A. (2002). J. Biol. Chem., 277, 42919-42925.
37. Kmiecik TE and Shalloway D. (1987). Cell, 49, 65-73.
38. Lando D, Peet DJ, Whelan DA, Gorman JJ and Whitelaw ML. (2002). Science, 295, 858-861.
39. Leung DW, Cachianes G, Kuang WJ, Goeddel DV and Ferrara N. (1989). Science, 246, 1306-1309.
40. Lill NL, Grossman SR, Ginsberg D, DeCaprio J and Livingston DM. (1997). Nature, 387, 823-827.
41. Liu XH, Kirschenbaum A, Lu M, Yao S, Dosoretz A, Holland JF and Levine AC. (2002). J. Biol. Chem., 277, 50081-50086.
42. Maxwell PH, Wiesener MS, Chang GW, Clifford SC, Vaux EC, Cockman ME, Wykoff CC, Pugh CW, Maher ER and Ratcliffe PJ. (1999). Nature, 399, 271-275.
43. Mayerhofer M, Valent P, Sperr WR, Griffin JD and Sillaber C. (2002). Blood, 100, 3767-3775.
44. Merika M, Williams AJ, Chen G, Collins T and Thanos D. (1998). Mol. Cell, 1, 277-287.
45. Minchenko A, Bauer T, Salceda S and Caro J. (1994). Lab. Invest., 71, 374-379.
46. Mukhopadhyay D, Tsiokas L, Zhou XM, Foster D, Brugge JS and Sukhatme VP. (1995). Nature, 375, 577-581.
47. Nakashima K, Yanagisawa M, Arakawa H, Kimura N, Hisatsune T, Kawabata M, Miyazono K and Taga T. (1999). Science, 284, 479-482.
48. Nam DH, Park K, Suh YL and Kim JH. (2004). Oncol. Rep., 11, 863-869.
49. Namiki A, Brogi E, Kearney M, Kim EA, Wu T, Couffinhal T, Varticovski L and Isner JM. (1995). J. Biol. Chem., 270, 31189-31195.
50. Niedergethmann M, Hildenbrand R, Wostbrock B, Hartel M, Sturm JW, Richter A and Post S. (2002). Pancreas, 25, 122-129.
51. Niu G, Bowman T, Huang M, Shivers S, Reintgen D, Daud A, Chang A, Kraker A, Jove R and Yu H. (2002a). Oncogene, 21, 7001-7010.
52. Niu G, Wright KL, Huang M, Song L, Haura E, Turkson J, Zhang S, Wang T, Sinibaldi D, Coppola D, Heller R, Ellis LM, Karras J, Bromberg J, Pardoll D, Jove R and Yu H. (2002b). Oncogene, 21, 2000-2008.
53. Paulson M, Pisharody S, Pan L, Guadagno S, Mui AL and Levy DE. (1999). J. Biol. Chem., 274, 25343-25349.
54. Pugh CW, Ebert BL, Ebrahim O and Ratcliffe PJ. (1994). Biochim. Biophys. Acta., 1217, 297-306.
55. Ray S, Sherman CT, Lu M and Brasier AR. (2002). Mol. Endocrinol., 16, 824-836.
56. Schaefer LK, Wang S and Schaefer TS. (1999). Biochem. Biophys. Res. Commun., 266, 481-487.
57. Schuringa JJ, Schepers H, Vellenga E and Kruijer W. (2001). FEBS Lett., 495, 71-76.
58. Semenza GL. (2002). Intern. Med, 41, 79-83.
59. Semenza GL. (2003). Nat. Rev. Cancer, 3, 721-732.
60. Senger DR, Galli SJ, Dvorak AM, Perruzzi CA, Harvey VS and Dvorak HF. (1983). Science, 219, 983-985.
61. Senger DR, Ledbetter SR, Claffey KP, Papadopoulos-Sergiou A, Peruzzi CA and Detmar M. (1996). Am. J. Pathol., 149, 293-305.
62. Shweiki D, Itin A, Soffer D and Keshet E. (1992). Nature, 359, 843-845.
63. Staley CA, Parikh NU and Gallick GE. (1997). Cell. Growth Differ., 8, 269-274.
64. Stoeltzing O, Liu W, Reinmuth N, Fan F, Parikh AA, Bucana CD, Evans DB, Semenza GL and Ellis LM. (2003). Am. J. Pathol., 163, 1001-1011.
65. Summy JM and Gallick GE. (2003). Cancer Metasta. Rev., 22, 337-358.
66. Takahashi Y, Kitadai Y, Bucana CD, Cleary KR and Ellis LM. (1995). Cancer Res., 55, 3964-3968.
67. Talamonti MS, Roh MS, Curley SA and Gallick GE. (1993). J. Clin. Invest., 91, 53-60.
68. Thornton RD, Lane P, Borghaei RC, Pease EA, Caro J and Mochan E. (2000). Biochem. J., 350 (Part 1), 307-312.
69. Turkson J, Bowman T, Garcia R, Caldenhoven E, De Groot RP and Jove R. (1998). Mol. Cell. Biol., 18, 2545-2552.
70. Uehara M, Sano K, Ikeda H, Sekine J, Irie A, Yokota T, Tobita T, Ohba S and Inokuchi T. (2004). Oral. Oncol., 40, 321-325.
71. Watanabe Y, Lee SW, Detmar M, Ajioka I and Dvorak HF. (1997). Oncogene, 14, 2025-2032.
72. Wei D, Le X, Zheng L, Wang L, Frey JA, Gao AC, Peng Z, Huang S, Xiong HQ, Abbruzzese JL and Xie K. (2003). Oncogene, 22, 319-329.
73. Wiener JR, Nakano K, Kruzelock RP, Bucana CD, Bast Jr RC and Gallick GE. (1999). Clin. Cancer Res., 5, 2164-2170.
74. Xanthoudakis S and Curran T. (1992). EMBO J., 11, 653-665.
75. Yahata Y, Shirakata Y, Tokumaru S, Yamasaki K, Sayama K, Hanakawa Y, Detmar M and Hashimoto K. (2003). J. Biol. Chem., 278, 40026-40031.
76. Yamashita K, Bischer DJ, Hu J, Bishopric NH and Webster KA. (2001). J. Biol. Chem., 276, 12645-12653.
77. Yu CL, Meyer DJ, Campbell GS, Larner AC, Carter-Su C, Schwartz J and Jove R. (1995). Science, 269, 81-83.
78. Yuan W, Condorelli G, Caruso M, Felsani A and Giordano A. (1996). J. Biol. Chem., 271, 9009-9013.
79. Zelzer E, Levy Y, Kahana C, Shilo BZ, Rubinstein M and Cohen B. (1998). EMBO J., 17, 5085-5094.
80. Zhang JJ, Vinkemeier U, Gu W, Chakravarti D, Horvath CM and Darnell Jr JE. (1996). Proc. Natl. Acad. Sci. USA, 93, 15092-15096.
81. Ziel KA, Campbell CC, Wilson GL and Gillespie MN. (2004). FASEB J., 18, 986-988.