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Volumn 13, Issue 12, 2012, Pages 16929-16944

DNA damage and repair in atherosclerosis: Current insights and future perspectives

Author keywords

Atherosclerosis; DNA damage; DNA repair; MiRNAs

Indexed keywords

MICRORNA; SIMVASTATIN;

EID: 84871703774     PISSN: 16616596     EISSN: 14220067     Source Type: Journal    
DOI: 10.3390/ijms131216929     Document Type: Review
Times cited : (56)

References (95)
  • 1
    • 39749191084 scopus 로고    scopus 로고
    • Heart disease and stroke statistics-2008 update: A report from the American Heart Association Statistics Committee and Stroke Statistics Subcommittee
    • Rosamond, W.; Flegal, K.; Furie, K.; Go, A.; Greenlund, K.; Haase, N.; Hailpern, S.M.; Ho, M.; Howard, V.; Kissela, B.; et al. Heart disease and stroke statistics-2008 update: A report from the American Heart Association Statistics Committee and Stroke Statistics Subcommittee. Circulation 2008, 117, e25-e146.
    • (2008) Circulation , vol.117
    • Rosamond, W.1    Flegal, K.2    Furie, K.3    Go, A.4    Greenlund, K.5    Haase, N.6    Hailpern, S.M.7    Ho, M.8    Howard, V.9    Kissela, B.10
  • 2
    • 0027807211 scopus 로고
    • Rous-Whipple Award Lecture. Atherosclerosis: A defense mechanism gone awry
    • Ross, R. Rous-Whipple Award Lecture. Atherosclerosis: A defense mechanism gone awry. Am. J. Pathol. 1993, 143, 987-1002.
    • (1993) Am. J. Pathol. , vol.143 , pp. 987-1002
    • Ross, R.1
  • 3
    • 67649256003 scopus 로고    scopus 로고
    • Metabolic syndrome, diabetes and atherosclerosis: Influence of gene-environment interaction
    • Andreassi, M.G. Metabolic syndrome, diabetes and atherosclerosis: Influence of gene-environment interaction. Mutat. Res. 2009, 667, 35-43.
    • (2009) Mutat. Res. , vol.667 , pp. 35-43
    • Andreassi, M.G.1
  • 4
    • 79956319051 scopus 로고    scopus 로고
    • Progress and challenges in translating the biology of atherosclerosis
    • Libby, P.; Ridker, P.M.; Hansson, G.K. Progress and challenges in translating the biology of atherosclerosis. Nature 2011, 473, 317-325.
    • (2011) Nature , vol.473 , pp. 317-325
    • Libby, P.1    Ridker, P.M.2    Hansson, G.K.3
  • 5
    • 49749093770 scopus 로고    scopus 로고
    • DNA damage, vascular senescence and atherosclerosis
    • Andreassi, M.G. DNA damage, vascular senescence and atherosclerosis. J. Mol. Med. (Berl.) 2008, 86, 1033-1043.
    • (2008) J. Mol. Med. (Berl.) , vol.86 , pp. 1033-1043
    • Andreassi, M.G.1
  • 6
    • 84863667325 scopus 로고    scopus 로고
    • Aging and atherosclerosis: Mechanisms, functional consequences, and potential therapeutics for cellular senescence
    • Wang, J.C.; Bennett, M. Aging and atherosclerosis: mechanisms, functional consequences, and potential therapeutics for cellular senescence. Circ. Res. 2012, 111, 245-259.
    • (2012) Circ. Res. , vol.111 , pp. 245-259
    • Wang, J.C.1    Bennett, M.2
  • 7
    • 41149139491 scopus 로고    scopus 로고
    • Angiotensin II-mediated oxidative DNA damage accelerates cellular senescence in cultured human vascular smooth muscle cells via telomere-dependent and independent pathways
    • Herbert, K.E.; Mistry, Y.; Hastings, R.; Poolman, T.; Niklason, L.; Williams, B. Angiotensin II-mediated oxidative DNA damage accelerates cellular senescence in cultured human vascular smooth muscle cells via telomere-dependent and independent pathways. Circ. Res. 2008, 102, 201-208.
    • (2008) Circ. Res. , vol.102 , pp. 201-208
    • Herbert, K.E.1    Mistry, Y.2    Hastings, R.3    Poolman, T.4    Niklason, L.5    Williams, B.6
  • 8
    • 0035078313 scopus 로고    scopus 로고
    • Increased DNA alterations in atherosclerotic lesions of individuals lacking the GSTM1 genotype
    • Izzotti, A.; Cartiglia, C.; Lewtas, J.; De Flora, S. Increased DNA alterations in atherosclerotic lesions of individuals lacking the GSTM1 genotype. FASEB J. 2001, 15, 752-757.
    • (2001) FASEB J. , vol.15 , pp. 752-757
    • Izzotti, A.1    Cartiglia, C.2    Lewtas, J.3    de Flora, S.4
  • 9
    • 78650656433 scopus 로고    scopus 로고
    • The association of micronucleus frequency with obesity, diabetes and cardiovascular disease
    • Andreassi, M.G.; Barale, R.; Iozzo, P.; Picano, E. The association of micronucleus frequency with obesity, diabetes and cardiovascular disease. Mutagenesis 2011, 26, 77-83.
    • (2011) Mutagenesis , vol.26 , pp. 77-83
    • Andreassi, M.G.1    Barale, R.2    Iozzo, P.3    Picano, E.4
  • 10
    • 0030599034 scopus 로고    scopus 로고
    • Instability at the H-ras minisatellite in human atherosclerotic plaques
    • Kiaris, H.; Hatzistamou, J.; Spandidos, D.A. Instability at the H-ras minisatellite in human atherosclerotic plaques. Atherosclerosis 1996, 125, 47-51.
    • (1996) Atherosclerosis , vol.125 , pp. 47-51
    • Kiaris, H.1    Hatzistamou, J.2    Spandidos, D.A.3
  • 11
    • 0030570780 scopus 로고    scopus 로고
    • Loss of heterozygosity and microsatellite instability in human atherosclerotic plaques
    • Hatzistamou, J.; Kiaris, H.; Ergazaki, M.; Spandidos, D.A. Loss of heterozygosity and microsatellite instability in human atherosclerotic plaques. Biochem. Biophys. Res. Commun. 1996, 225, 186-190.
    • (1996) Biochem. Biophys. Res. Commun. , vol.225 , pp. 186-190
    • Hatzistamou, J.1    Kiaris, H.2    Ergazaki, M.3    Spandidos, D.A.4
  • 15
    • 0031203642 scopus 로고    scopus 로고
    • Cytogenetic aspects of cell proliferation in atherosclerotic plaques
    • Matturri, L.; Cazzullo, A.; Turconi, P.; Lavezzi, A.M. Cytogenetic aspects of cell proliferation in atherosclerotic plaques. Cardiologia 1997, 42, 833-836.
    • (1997) Cardiologia , vol.42 , pp. 833-836
    • Matturri, L.1    Cazzullo, A.2    Turconi, P.3    Lavezzi, A.M.4
  • 17
    • 34447292992 scopus 로고    scopus 로고
    • Survival of atherosclerotic patients as related to oxidative stress and gene polymorphisms
    • Izzotti, A.; Piana, A.; Minniti, G.; Vercelli, M.; Perrone, L.; de Flora, S. Survival of atherosclerotic patients as related to oxidative stress and gene polymorphisms. Mutat. Res. 2007, 621, 119-128.
    • (2007) Mutat. Res. , vol.621 , pp. 119-128
    • Izzotti, A.1    Piana, A.2    Minniti, G.3    Vercelli, M.4    Perrone, L.5    de Flora, S.6
  • 18
    • 34447289608 scopus 로고    scopus 로고
    • Lipid peroxidation-derived etheno-DNA adducts in human atherosclerotic lesions
    • Nair, J.; de Flora, S.; Izzotti, A.; Bartsch, H. Lipid peroxidation-derived etheno-DNA adducts in human atherosclerotic lesions. Mutat. Res. 2007, 621, 95-105.
    • (2007) Mutat. Res. , vol.621 , pp. 95-105
    • Nair, J.1    de Flora, S.2    Izzotti, A.3    Bartsch, H.4
  • 19
    • 25844435651 scopus 로고    scopus 로고
    • Lymphocyte DNA damage in patients with acute coronary syndrome and its relationship with severity of acute coronary syndrome
    • Demirbag, R.; Yilmaz, R.; Gur, M.; Kocyigit, A.; Celik, H.; Guzel, S.; Selek, S. Lymphocyte DNA damage in patients with acute coronary syndrome and its relationship with severity of acute coronary syndrome. Mutat. Res. 2005, 578, 298-307.
    • (2005) Mutat. Res. , vol.578 , pp. 298-307
    • Demirbag, R.1    Yilmaz, R.2    Gur, M.3    Kocyigit, A.4    Celik, H.5    Guzel, S.6    Selek, S.7
  • 20
    • 55249087914 scopus 로고    scopus 로고
    • Relation of increased chromosomal damage to future adverse cardiac events in patients with known coronary artery disease
    • Federici, C.; Botto, N.; Manfredi, S.; Rizza, A.; del Fiandra, M.; Andreassi, M.G. Relation of increased chromosomal damage to future adverse cardiac events in patients with known coronary artery disease. Am. J. Cardiol. 2008, 102, 1296-1300.
    • (2008) Am. J. Cardiol. , vol.102 , pp. 1296-1300
    • Federici, C.1    Botto, N.2    Manfredi, S.3    Rizza, A.4    del Fiandra, M.5    Andreassi, M.G.6
  • 21
    • 33747625689 scopus 로고    scopus 로고
    • Vascular smooth muscle cells undergo telomere-based senescence in human atherosclerosis: Effects of telomerase and oxidative stress
    • Matthews, C.; Gorenne, I.; Scott, S.; Figg, N.; Kirkpatrick, P.; Ritchie, A.; Goddard, M.; Bennett, M. Vascular smooth muscle cells undergo telomere-based senescence in human atherosclerosis: Effects of telomerase and oxidative stress. Circ. Res. 2006, 99, 156-164.
    • (2006) Circ. Res. , vol.99 , pp. 156-164
    • Matthews, C.1    Gorenne, I.2    Scott, S.3    Figg, N.4    Kirkpatrick, P.5    Ritchie, A.6    Goddard, M.7    Bennett, M.8
  • 23
    • 54449083115 scopus 로고    scopus 로고
    • Statins use a novel Nijmegen breakage syndrome-1-dependent pathway to accelerate DNA repair in vascular smooth muscle cells
    • Mahmoudi, M.; Gorenne, I.; Mercer, J.; Figg, N.; Littlewood, T.; Bennett, M. Statins use a novel Nijmegen breakage syndrome-1-dependent pathway to accelerate DNA repair in vascular smooth muscle cells. Circ. Res. 2008, 103, 717-725.
    • (2008) Circ. Res. , vol.103 , pp. 717-725
    • Mahmoudi, M.1    Gorenne, I.2    Mercer, J.3    Figg, N.4    Littlewood, T.5    Bennett, M.6
  • 28
    • 70350065725 scopus 로고    scopus 로고
    • Disorders of nucleotide excision repair: The genetic and molecular basis of heterogeneity
    • Cleaver, J.E.; Lam, E.T.; Revet, I. Disorders of nucleotide excision repair: The genetic and molecular basis of heterogeneity. Nat. Rev. Genet. 2009, 10, 756-768.
    • (2009) Nat. Rev. Genet. , vol.10 , pp. 756-768
    • Cleaver, J.E.1    Lam, E.T.2    Revet, I.3
  • 29
    • 0030861915 scopus 로고    scopus 로고
    • DNA glycosylases in the base excision repair of DNA
    • Krokan, H.E.; Standal, R.; Slupphaug, G. DNA glycosylases in the base excision repair of DNA. Biochem. J. 1997, 325, 1-16.
    • (1997) Biochem. J. , vol.325 , pp. 1-16
    • Krokan, H.E.1    Standal, R.2    Slupphaug, G.3
  • 30
    • 84857891632 scopus 로고    scopus 로고
    • On PAR with PARP: Cellular stress signaling through poly(ADP-ribose) and PARP-1
    • Luo, X.; Kraus, W.L. On PAR with PARP: Cellular stress signaling through poly(ADP-ribose) and PARP-1. Genes Dev. 2012, 26, 417-432.
    • (2012) Genes Dev. , vol.26 , pp. 417-432
    • Luo, X.1    Kraus, W.L.2
  • 32
    • 0036733355 scopus 로고    scopus 로고
    • The therapeutic potential of poly(ADP-ribose) polymerase inhibitors
    • Virag, L.; Szabo, C. The therapeutic potential of poly(ADP-ribose) polymerase inhibitors. Pharmacol. Rev. 2002, 54, 375-429.
    • (2002) Pharmacol. Rev. , vol.54 , pp. 375-429
    • Virag, L.1    Szabo, C.2
  • 33
    • 78149425175 scopus 로고    scopus 로고
    • Regulation of homologous recombination in eukaryotes
    • Heyer, W.D.; Ehmsen, K.T.; Liu, J. Regulation of homologous recombination in eukaryotes. Annu. Rev. Genet. 2010, 44, 113-139.
    • (2010) Annu. Rev. Genet. , vol.44 , pp. 113-139
    • Heyer, W.D.1    Ehmsen, K.T.2    Liu, J.3
  • 35
    • 0042839614 scopus 로고    scopus 로고
    • Mechanism and regulation of human non-homologous DNA end-joining
    • Lieber, M.R.; Ma, Y.; Pannicke, U.; Schwarz, K. Mechanism and regulation of human non-homologous DNA end-joining. Nat. Rev. Mol. Cell Biol. 2003, 4, 712-720.
    • (2003) Nat. Rev. Mol. Cell Biol. , vol.4 , pp. 712-720
    • Lieber, M.R.1    Ma, Y.2    Pannicke, U.3    Schwarz, K.4
  • 36
    • 0035902108 scopus 로고    scopus 로고
    • Genome maintenance mechanisms for preventing cancer
    • Hoeijmakers, J.H. Genome maintenance mechanisms for preventing cancer. Nature 2001, 411, 366-374.
    • (2001) Nature , vol.411 , pp. 366-374
    • Hoeijmakers, J.H.1
  • 37
    • 65549088533 scopus 로고    scopus 로고
    • ATR and H2AX cooperate in maintaining genome stability under replication stress
    • Chanoux, R.A.; Yin, B.; Urtishak, K.A.; Asare, A.; Bassing, C.H.; Brown, E.J. ATR and H2AX cooperate in maintaining genome stability under replication stress. J. Biol. Chem. 2009, 284, 5994-6003.
    • (2009) J. Biol. Chem. , vol.284 , pp. 5994-6003
    • Chanoux, R.A.1    Yin, B.2    Urtishak, K.A.3    Asare, A.4    Bassing, C.H.5    Brown, E.J.6
  • 38
    • 38049150586 scopus 로고    scopus 로고
    • The DNA damage response pathways: At the crossroad of protein modifications
    • Huen, M.S.; Chen, J. The DNA damage response pathways: At the crossroad of protein modifications. Cell Res. 2008, 18, 8-16.
    • (2008) Cell Res. , vol.18 , pp. 8-16
    • Huen, M.S.1    Chen, J.2
  • 39
    • 58149105457 scopus 로고    scopus 로고
    • A review of Sirt1 and Sirt1 modulators in cardiovascular and metabolic diseases
    • Pillarisetti, S. A review of Sirt1 and Sirt1 modulators in cardiovascular and metabolic diseases. Recent Pat. Cardiovasc. Drug Discov. 2008, 3, 156-164.
    • (2008) Recent Pat. Cardiovasc. Drug Discov. , vol.3 , pp. 156-164
    • Pillarisetti, S.1
  • 41
    • 39149116326 scopus 로고    scopus 로고
    • AsSIRTing the DNA damage response
    • Gorospe, M.; de Cabo, R. AsSIRTing the DNA damage response. Trends Cell Biol. 2008, 18, 77-83.
    • (2008) Trends Cell Biol. , vol.18 , pp. 77-83
    • Gorospe, M.1    de Cabo, R.2
  • 42
    • 37549016377 scopus 로고    scopus 로고
    • A functional link between SIRT1 deacetylase and NBS1 in DNA damage response
    • Yuan, Z.; Seto, E. A functional link between SIRT1 deacetylase and NBS1 in DNA damage response. Cell Cycle 2007, 6, 2869-2871.
    • (2007) Cell Cycle , vol.6 , pp. 2869-2871
    • Yuan, Z.1    Seto, E.2
  • 46
    • 77956550868 scopus 로고    scopus 로고
    • Human SIRT6 promotes DNA end resection through CtIP deacetylation
    • Kaidi, A.; Weinert, B.T.; Choudhary, C.; Jackson, S.P. Human SIRT6 promotes DNA end resection through CtIP deacetylation. Science 2010, 329, 1348-1353.
    • (2010) Science , vol.329 , pp. 1348-1353
    • Kaidi, A.1    Weinert, B.T.2    Choudhary, C.3    Jackson, S.P.4
  • 48
    • 84864701748 scopus 로고    scopus 로고
    • Pathological neoangiogenesis depends on oxidative stress regulation by ATM
    • Okuno, Y.; Nakamura-Ishizu, A.; Otsu, K.; Suda, T.; Kubota, Y. Pathological neoangiogenesis depends on oxidative stress regulation by ATM. Nat. Med. 2012, 18, 1208-1216.
    • (2012) Nat. Med. , vol.18 , pp. 1208-1216
    • Okuno, Y.1    Nakamura-Ishizu, A.2    Otsu, K.3    Suda, T.4    Kubota, Y.5
  • 49
    • 35148896262 scopus 로고    scopus 로고
    • Role of poly(ADP-ribose) polymerase 1 (PARP-1) in cardiovascular diseases: The therapeutic potential of PARP inhibitors
    • Pacher, P.; Szabo, C. Role of poly(ADP-ribose) polymerase 1 (PARP-1) in cardiovascular diseases: the therapeutic potential of PARP inhibitors. Cardiovasc. Drug Rev. 2007, 25, 235-260.
    • (2007) Cardiovasc. Drug Rev. , vol.25 , pp. 235-260
    • Pacher, P.1    Szabo, C.2
  • 50
    • 0037143598 scopus 로고    scopus 로고
    • Elevated levels of oxidative DNA damage and DNA repair enzymes in human atherosclerotic plaques
    • Martinet, W.; Knaapen, M.W.; De Meyer, G.R.; Herman, A.G.; Kockx, M.M. Elevated levels of oxidative DNA damage and DNA repair enzymes in human atherosclerotic plaques. Circulation 2002, 106, 927-932.
    • (2002) Circulation , vol.106 , pp. 927-932
    • Martinet, W.1    Knaapen, M.W.2    de Meyer, G.R.3    Herman, A.G.4    Kockx, M.M.5
  • 51
    • 3042643028 scopus 로고    scopus 로고
    • Restoration of the endothelial function in the aortic rings of apolipoprotein E deficient mice by pharmacological inhibition of the nuclear enzyme poly(ADP-ribose) polymerase
    • Benko, R.; Pacher, P.; Vaslin, A.; Kollai, M.; Szabo, C. Restoration of the endothelial function in the aortic rings of apolipoprotein E deficient mice by pharmacological inhibition of the nuclear enzyme poly(ADP-ribose) polymerase. Life Sci. 2004, 75, 1255-1261.
    • (2004) Life Sci. , vol.75 , pp. 1255-1261
    • Benko, R.1    Pacher, P.2    Vaslin, A.3    Kollai, M.4    Szabo, C.5
  • 52
    • 34250648890 scopus 로고    scopus 로고
    • Poly(ADP-ribose) polymerase inhibition improves endothelial dysfunction induced by reactive oxidant hydrogen peroxide in vitro
    • Radovits, T.; Lin, L.N.; Zotkina, J.; Gero, D.; Szabo, C.; Karck, M.; Szabo, G. Poly(ADP-ribose) polymerase inhibition improves endothelial dysfunction induced by reactive oxidant hydrogen peroxide in vitro. Eur. J. Pharmacol. 2007, 564, 158-166.
    • (2007) Eur. J. Pharmacol. , vol.564 , pp. 158-166
    • Radovits, T.1    Lin, L.N.2    Zotkina, J.3    Gero, D.4    Szabo, C.5    Karck, M.6    Szabo, G.7
  • 55
    • 0034766616 scopus 로고    scopus 로고
    • Loss of heterozygosity on chromosomes 1, 2, 8, 9 and 17 in cerebral atherosclerotic plaques
    • Miniati, P.; Sourvinos, G.; Michalodimitrakis, M.; Spandidos, D.A. Loss of heterozygosity on chromosomes 1, 2, 8, 9 and 17 in cerebral atherosclerotic plaques. Int. J. Biol. Markers 2001, 16, 167-171.
    • (2001) Int. J. Biol. Markers , vol.16 , pp. 167-171
    • Miniati, P.1    Sourvinos, G.2    Michalodimitrakis, M.3    Spandidos, D.A.4
  • 58
    • 54149103338 scopus 로고    scopus 로고
    • Endothelium-specific overexpression of class III deacetylase SIRT1 decreases atherosclerosis in apolipoprotein E-deficient mice
    • Zhang, Q.J.; Wang, Z.; Chen, H.Z.; Zhou, S.; Zheng, W.; Liu, G.; Wei, Y.S.; Cai, H.; Liu, D.P.; Liang, C.C. Endothelium-specific overexpression of class III deacetylase SIRT1 decreases atherosclerosis in apolipoprotein E-deficient mice. Cardiovasc. Res. 2008, 80, 191-199.
    • (2008) Cardiovasc. Res. , vol.80 , pp. 191-199
    • Zhang, Q.J.1    Wang, Z.2    Chen, H.Z.3    Zhou, S.4    Zheng, W.5    Liu, G.6    Wei, Y.S.7    Cai, H.8    Liu, D.P.9    Liang, C.C.10
  • 59
    • 0024826071 scopus 로고
    • Atherosclerosis-and age-related multinucleated variant endothelial cells in primary culture from human aorta
    • Tokunaga, O.; Fan, J.L.; Watanabe, T. Atherosclerosis-and age-related multinucleated variant endothelial cells in primary culture from human aorta. Am. J. Pathol. 1989, 135, 967-976.
    • (1989) Am. J. Pathol. , vol.135 , pp. 967-976
    • Tokunaga, O.1    Fan, J.L.2    Watanabe, T.3
  • 61
    • 73549125217 scopus 로고    scopus 로고
    • Polyploidy impairs human aortic endothelial cell function and is prevented by nicotinamide phosphoribosyltransferase
    • Borradaile, N.M.; Pickering, J.G. Polyploidy impairs human aortic endothelial cell function and is prevented by nicotinamide phosphoribosyltransferase. Am. J. Physiol. Cell Physiol. 2010, 298, C66-C74.
    • (2010) Am. J. Physiol. Cell Physiol. , vol.298
    • Borradaile, N.M.1    Pickering, J.G.2
  • 63
    • 36749015095 scopus 로고    scopus 로고
    • DNA repair gene XRCC1 and XPD polymorphisms and their association with coronary artery disease risks and micronucleus frequency
    • Guven, M.; Guven, G.S.; Oz, E.; Ozaydin, A.; Batar, B.; Ulutin, T.; Hacihanefioglu, S.; Domanic, N. DNA repair gene XRCC1 and XPD polymorphisms and their association with coronary artery disease risks and micronucleus frequency. Heart Vessels 2007, 22, 355-360.
    • (2007) Heart Vessels , vol.22 , pp. 355-360
    • Guven, M.1    Guven, G.S.2    Oz, E.3    Ozaydin, A.4    Batar, B.5    Ulutin, T.6    Hacihanefioglu, S.7    Domanic, N.8
  • 64
    • 33745209635 scopus 로고    scopus 로고
    • DNA damage and repair in atherosclerosis
    • Mahmoudi, M.; Mercer, J.; Bennett, M. DNA damage and repair in atherosclerosis. Cardiovasc. Res. 2006, 71, 259-268.
    • (2006) Cardiovasc. Res. , vol.71 , pp. 259-268
    • Mahmoudi, M.1    Mercer, J.2    Bennett, M.3
  • 65
    • 84860344692 scopus 로고    scopus 로고
    • Polymorphisms of DNA repair pathway genes and cigarette smoking in relation to susceptibility to large artery atherosclerotic stroke among ethnic Chinese in Taiwan
    • Shyu, H.Y.; Shieh, J.C.; Ji-Ho, L.; Wang, H.W.; Cheng, C.W. Polymorphisms of DNA repair pathway genes and cigarette smoking in relation to susceptibility to large artery atherosclerotic stroke among ethnic Chinese in Taiwan. J. Atheroscler. Thromb. 2012, 19, 316-325.
    • (2012) J. Atheroscler. Thromb. , vol.19 , pp. 316-325
    • Shyu, H.Y.1    Shieh, J.C.2    Ji-Ho, L.3    Wang, H.W.4    Cheng, C.W.5
  • 66
    • 84855172461 scopus 로고    scopus 로고
    • SIRTUIN 1 gene polymorphisms are associated with cholesterol metabolism and coronary artery calcification in Japanese hemodialysis patients
    • Shimoyama, Y.; Mitsuda, Y.; Tsuruta, Y.; Suzuki, K.; Hamajima, N.; Niwa, T. SIRTUIN 1 gene polymorphisms are associated with cholesterol metabolism and coronary artery calcification in Japanese hemodialysis patients. J. Ren. Nutr. 2012, 22, 114-119.
    • (2012) J. Ren. Nutr. , vol.22 , pp. 114-119
    • Shimoyama, Y.1    Mitsuda, Y.2    Tsuruta, Y.3    Suzuki, K.4    Hamajima, N.5    Niwa, T.6
  • 68
    • 77449110369 scopus 로고    scopus 로고
    • Chromosome 9p21 and cardiovascular disease: The story unfolds
    • Samani, N.J.; Schunkert, H. Chromosome 9p21 and cardiovascular disease: the story unfolds. Circ. Cardiovasc. Genet. 2008, 1, 81-84.
    • (2008) Circ. Cardiovasc. Genet. , vol.1 , pp. 81-84
    • Samani, N.J.1    Schunkert, H.2
  • 70
    • 84860130921 scopus 로고    scopus 로고
    • Role of miRNAs in muscle stem cell biology: Proliferation, differentiation and death
    • Crippa, S.; Cassano, M.; Sampaolesi, M. Role of miRNAs in muscle stem cell biology: Proliferation, differentiation and death. Curr. Pharm. Des. 2012, 18, 1718-1729.
    • (2012) Curr. Pharm. Des. , vol.18 , pp. 1718-1729
    • Crippa, S.1    Cassano, M.2    Sampaolesi, M.3
  • 71
    • 28144449396 scopus 로고    scopus 로고
    • Developmental biology. Encountering microRNAs in cell fate signaling
    • Karp, X.; Ambros, V. Developmental biology. Encountering microRNAs in cell fate signaling. Science 2005, 310, 1288-1289.
    • (2005) Science , vol.310 , pp. 1288-1289
    • Karp, X.1    Ambros, V.2
  • 73
    • 7444243756 scopus 로고    scopus 로고
    • MicroRNAs and the regulation of cell death
    • Xu, P.; Guo, M.; Hay, B.A. MicroRNAs and the regulation of cell death. Trends Genet. 2004, 20, 617-624.
    • (2004) Trends Genet. , vol.20 , pp. 617-624
    • Xu, P.1    Guo, M.2    Hay, B.A.3
  • 74
    • 79958207254 scopus 로고    scopus 로고
    • MicroRNAs: New players in the DNA damage response
    • Hu, H.; Gatti, R.A. MicroRNAs: New players in the DNA damage response. J. Mol. Cell Biol. 2011, 3, 151-158.
    • (2011) J. Mol. Cell Biol. , vol.3 , pp. 151-158
    • Hu, H.1    Gatti, R.A.2
  • 75
    • 58249088751 scopus 로고    scopus 로고
    • MicroRNAs: Target recognition and regulatory functions
    • Bartel, D.P. MicroRNAs: Target recognition and regulatory functions. Cell 2009, 136, 215-233.
    • (2009) Cell , vol.136 , pp. 215-233
    • Bartel, D.P.1
  • 77
    • 82155167635 scopus 로고    scopus 로고
    • MicroRNAs and vascular (dys)function
    • Hartmann, D.; Thum, T. MicroRNAs and vascular (dys)function. Vascul. Pharmacol. 2011, 55, 92-105.
    • (2011) Vascul. Pharmacol. , vol.55 , pp. 92-105
    • Hartmann, D.1    Thum, T.2
  • 78
    • 84855244103 scopus 로고    scopus 로고
    • MicroRNA therapeutics in cardiovascular medicine
    • Thum, T. MicroRNA therapeutics in cardiovascular medicine. EMBO Mol. Med. 2012, 4, 3-14.
    • (2012) EMBO Mol. Med. , vol.4 , pp. 3-14
    • Thum, T.1
  • 80
    • 34250773289 scopus 로고    scopus 로고
    • MicroRNAs and the failing heart
    • Mann, D.L. MicroRNAs and the failing heart. N. Eng. J. Med. 2007, 356, 2644-2645.
    • (2007) N. Eng. J. Med. , vol.356 , pp. 2644-2645
    • Mann, D.L.1
  • 87
    • 78650423960 scopus 로고    scopus 로고
    • Context-dependent bidirectional regulation of the MutS homolog 2 by transforming growth factor beta contributes to chemoresistance in breast cancer cells
    • Yu, Y.; Wang, Y.; Ren, X.; Tsuyada, A.; Li, A.; Liu, L.J.; Wang, S.E. Context-dependent bidirectional regulation of the MutS homolog 2 by transforming growth factor beta contributes to chemoresistance in breast cancer cells. Mol. Cancer Res. 2010, 8, 1633-1642.
    • (2010) Mol. Cancer Res. , vol.8 , pp. 1633-1642
    • Yu, Y.1    Wang, Y.2    Ren, X.3    Tsuyada, A.4    Li, A.5    Liu, L.J.6    Wang, S.E.7
  • 88
    • 65249115670 scopus 로고    scopus 로고
    • Involvement of MicroRNAs in hydrogen peroxide-mediated gene regulation and cellular injury response in vascular smooth muscle cells
    • Lin, Y.; Liu, X.; Cheng, Y.; Yang, J.; Huo, Y.; Zhang, C. Involvement of MicroRNAs in hydrogen peroxide-mediated gene regulation and cellular injury response in vascular smooth muscle cells. J. Biol. Chem. 2009, 284, 7903-7913.
    • (2009) J. Biol. Chem. , vol.284 , pp. 7903-7913
    • Lin, Y.1    Liu, X.2    Cheng, Y.3    Yang, J.4    Huo, Y.5    Zhang, C.6
  • 90
    • 70350504453 scopus 로고    scopus 로고
    • The DNA-damage response in human biology and disease
    • Jackson, S.P.; Bartek, J. The DNA-damage response in human biology and disease. Nature 2009, 461, 1071-1078.
    • (2009) Nature , vol.461 , pp. 1071-1078
    • Jackson, S.P.1    Bartek, J.2
  • 91
    • 33746315961 scopus 로고    scopus 로고
    • Endothelial progenitor cell differentiation and senescence in an angiotensin II-infusion rat model
    • Kobayashi, K.; Imanishi, T.; Akasaka, T. Endothelial progenitor cell differentiation and senescence in an angiotensin II-infusion rat model. Hypertens. Res. 2006, 29, 449-455.
    • (2006) Hypertens. Res. , vol.29 , pp. 449-455
    • Kobayashi, K.1    Imanishi, T.2    Akasaka, T.3
  • 92
    • 33751076008 scopus 로고    scopus 로고
    • Effects of angiotensin II on NO bioavailability evaluated using a catheter-type NO sensor
    • Imanishi, T.; Kobayashi, K.; Kuroi, A.; Mochizuki, S.; Goto, M.; Yoshida, K.; Akasaka, T. Effects of angiotensin II on NO bioavailability evaluated using a catheter-type NO sensor. Hypertension 2006, 48, 1058-1065.
    • (2006) Hypertension , vol.48 , pp. 1058-1065
    • Imanishi, T.1    Kobayashi, K.2    Kuroi, A.3    Mochizuki, S.4    Goto, M.5    Yoshida, K.6    Akasaka, T.7
  • 95
    • 84862244159 scopus 로고    scopus 로고
    • Sirtuins and disease: The road ahead
    • doi:10.3389/fphar.2012.00004
    • Carafa, V.; Nebbioso, A.; Altucci, L. Sirtuins and disease: The road ahead. Front. Pharmacol. 2012, 3, doi:10.3389/fphar.2012.00004.
    • (2012) Front. Pharmacol. , vol.3
    • Carafa, V.1    Nebbioso, A.2    Altucci, L.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.