Regional vulnerability in Huntington's disease: FMRI-guided molecular analysis in patients and a mouse model of disease

Neurobiology of Disease

Volumn 52, Issue , 2013, Pages 84-93

  Lewandowski, Nicole M ^a   Bordelon, Yvette ^b   Brickman, Adam M ^a   Angulo, Sergio ^d   Khan, Usman ^a,c   Muraskin, Jordan ^a   Griffith, Erica Y ^a   Wasserman, Paula ^a   Menalled, Liliana ^d   Vonsattel, Jean Paul ^a   Marder, Karen ^a   Small, Scott A ^a   Moreno, Herman ^a,c  

^a Columbia University College of Physicians and Surgeons ^*  (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c SUNY Downstate Medical Center   (United States)

^d PSYCHOGENICS INC   (United States)

Author keywords

CBV; Huntington's disease; PPP1R7; WIF 1; YAC128

Indexed keywords

ADULT; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN BLOOD VOLUME; BRAIN MAPPING; BRAIN RADIOGRAPHY; BRAIN REGION; CAG REPEAT; CAUDATE NUCLEUS; CLINICAL ARTICLE; CONTROLLED STUDY; DISEASE MODEL; FEMALE; FUNCTIONAL MAGNETIC RESONANCE IMAGING; GENE; GENE EXPRESSION PROFILING; GENETIC VARIABILITY; HUMAN; HUMAN TISSUE; HUNTINGTON CHOREA; MALE; MICROARRAY ANALYSIS; MOLECULAR MODEL; MOUSE; MUTATIONAL ANALYSIS; NEUROIMAGING; NONHUMAN; NUCLEOTIDE SEQUENCE; PHENOTYPIC VARIATION; PRIMARY SOMATOSENSORY CORTEX; PRIORITY JOURNAL; PROTEIN PHOSPHATASE 1 REGULATORY SUBUNIT 7 GENE; SIGNAL TRANSDUCTION; WNT INHIBITORY FACTOR 1 GENE;

ADAPTOR PROTEINS, SIGNAL TRANSDUCING; ADULT; AGED; ANIMALS; CEREBROVASCULAR CIRCULATION; CORPUS STRIATUM; DISEASE MODELS, ANIMAL; FEMALE; GENE EXPRESSION REGULATION; HUMANS; HUNTINGTON DISEASE; MAGNETIC RESONANCE IMAGING; MALE; MICE; MICE, TRANSGENIC; MIDDLE AGED; MUTATION; NERVE TISSUE PROTEINS; NEURONS; NUCLEAR PROTEINS; PHENOTYPE; PROTEIN PHOSPHATASE 1; REPRESSOR PROTEINS;

EID: 84873526875     PISSN: 09699961     EISSN: 1095953X     Source Type: Journal    
DOI: 10.1016/j.nbd.2012.11.014     Document Type: Article

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