-
1
-
-
1642499152
-
Beta-amyloid peptides induce mitochondrial dysfunction and oxidative stress in astrocytes and death of neurons through activation of NADPH oxidase
-
Abramov AY, Canevari L, Duchen MR. 2004. Beta-amyloid peptides induce mitochondrial dysfunction and oxidative stress in astrocytes and death of neurons through activation of NADPH oxidase. J Neurosci 24: 565-575.
-
(2004)
J Neurosci
, vol.24
, pp. 565-575
-
-
Abramov, A.Y.1
Canevari, L.2
Duchen, M.R.3
-
2
-
-
0037363599
-
Involvement of calcineurin in the neurotoxic effects induced by amyloid-β and prion peptides
-
Agostinho P, Oliveira CR. 2003. Involvement of calcineurin in the neurotoxic effects induced by amyloid-β and prion peptides. Eur J Neurosci 17: 1189-1196.
-
(2003)
Eur J Neurosci
, vol.17
, pp. 1189-1196
-
-
Agostinho, P.1
Oliveira, C.R.2
-
3
-
-
0025183708
-
Basic local alignment search tool
-
Altschul SF, Gish W, Miller W, Myers EW, Lipman DJ. 1990. Basic local alignment search tool. J Mol Biol 215: 403-410.
-
(1990)
J Mol Biol
, vol.215
, pp. 403-410
-
-
Altschul, S.F.1
Gish, W.2
Miller, W.3
Myers, E.W.4
Lipman, D.J.5
-
5
-
-
0028207907
-
Amyloid β peptide induces necrosis rather than apoptosis
-
Behl C, Davis JB, Klier FG, Schubert D. 1994. Amyloid β peptide induces necrosis rather than apoptosis. Brain Res 645: 253-264.
-
(1994)
Brain Res
, vol.645
, pp. 253-264
-
-
Behl, C.1
Davis, J.B.2
Klier, F.G.3
Schubert, D.4
-
6
-
-
58849117092
-
Transcriptional regulatory functions of mammalian AP-endonuclease (APE1/Ref-1), an essential multifunctional protein
-
Bhakat KK, Mantha AK, Mitra S. 2009. Transcriptional regulatory functions of mammalian AP-endonuclease (APE1/Ref-1), an essential multifunctional protein. Antioxid Redox Signal 11: 621-638.
-
(2009)
Antioxid Redox Signal
, vol.11
, pp. 621-638
-
-
Bhakat, K.K.1
Mantha, A.K.2
Mitra, S.3
-
7
-
-
34248178463
-
Differential regulation of BACE1 promoter activity by nuclear factor-kappaB in neurons and glia upon exposure to β-amyloid peptides
-
Bourne KZ, Ferrari DC, Lange-Dohna C, Rossner S, Wood TG, Perez-Polo JR. 2007. Differential regulation of BACE1 promoter activity by nuclear factor-kappaB in neurons and glia upon exposure to β-amyloid peptides. J Neurosci Res 85: 1194-1204.
-
(2007)
J Neurosci Res
, vol.85
, pp. 1194-1204
-
-
Bourne, K.Z.1
Ferrari, D.C.2
Lange-Dohna, C.3
Rossner, S.4
Wood, T.G.5
Perez-Polo, J.R.6
-
8
-
-
33646144212
-
Redox proteomics identification of oxidatively modified hippocampal proteins in mild cognitive impairment: insights into the development of Alzheimer's disease
-
Butterfield DA, Poon HF, St. Clair D, Keller JN, Pierce WM, Klein JB, Markesbery WR. 2006. Redox proteomics identification of oxidatively modified hippocampal proteins in mild cognitive impairment: insights into the development of Alzheimer's disease. Neurobiol Dis 22: 223-232.
-
(2006)
Neurobiol Dis
, vol.22
, pp. 223-232
-
-
Butterfield, D.A.1
Poon, H.F.S.T.2
Clair, D.3
Keller, J.N.4
Pierce, W.M.5
Klein, J.B.6
Markesbery, W.R.7
-
9
-
-
0037438577
-
The GDP exchange factor AND-34 is expressed in B cells, associates with HEF1, and activates Cdc42
-
Cai D, Felekkis KN, Near RI, O'Neill GM, van Seventer JM, Golemis EA, Lerner A. 2003. The GDP exchange factor AND-34 is expressed in B cells, associates with HEF1, and activates Cdc42. J Immunol 170: 969-978.
-
(2003)
J Immunol
, vol.170
, pp. 969-978
-
-
Cai, D.1
Felekkis, K.N.2
Near, R.I.3
O'Neill, G.M.4
van Seventer, J.M.5
Golemis, E.A.6
Lerner, A.7
-
10
-
-
73449089819
-
Nitric oxide in cell survival: a janus molecule
-
Calabrese V, Cornelius C, Rizzarelli E, Owen JB, Dinkova-Kostova AT, Butterfield DA. 2009. Nitric oxide in cell survival: a janus molecule. Antioxid Redox Signal 11: 2717-2739.
-
(2009)
Antioxid Redox Signal
, vol.11
, pp. 2717-2739
-
-
Calabrese, V.1
Cornelius, C.2
Rizzarelli, E.3
Owen, J.B.4
Dinkova-Kostova, A.T.5
Butterfield, D.A.6
-
11
-
-
81855201861
-
Hormesis, cellular stress response and vitagenes as critical determinants in aging and longevity
-
Calabrese V, Cornelius C, Cuzzocrea S, Iavicoli I, Rizzarelli E, Calabrese EJ. 2011. Hormesis, cellular stress response and vitagenes as critical determinants in aging and longevity. Mol Aspects Med 32: 279-304.
-
(2011)
Mol Aspects Med
, vol.32
, pp. 279-304
-
-
Calabrese, V.1
Cornelius, C.2
Cuzzocrea, S.3
Iavicoli, I.4
Rizzarelli, E.5
Calabrese, E.J.6
-
12
-
-
33645928711
-
Identification and characterization of mitochondrial abasic (AP)-endonuclease in mammalian cells
-
Chattopadhyay R, Wiederhold L, Szczesny B, Boldogh I, Hazra TK, Izumi T, Mitra S. 2006. Identification and characterization of mitochondrial abasic (AP)-endonuclease in mammalian cells. Nucleic Acids Res 34: 2067-2076.
-
(2006)
Nucleic Acids Res
, vol.34
, pp. 2067-2076
-
-
Chattopadhyay, R.1
Wiederhold, L.2
Szczesny, B.3
Boldogh, I.4
Hazra, T.K.5
Izumi, T.6
Mitra, S.7
-
13
-
-
57349170258
-
Regulatory role of human AP-endonuclease (APE1/Ref-1) in YB-1-mediated activation of the multidrug resistance gene MDR1
-
Chattopadhyay R, Das S, Maiti AK, Boldogh I, Xie J, Hazra TK, Kohno K, Mitra S, Bhakat KK. 2008. Regulatory role of human AP-endonuclease (APE1/Ref-1) in YB-1-mediated activation of the multidrug resistance gene MDR1. Mol Cell Biol 28: 7066-7080.
-
(2008)
Mol Cell Biol
, vol.28
, pp. 7066-7080
-
-
Chattopadhyay, R.1
Das, S.2
Maiti, A.K.3
Boldogh, I.4
Xie, J.5
Hazra, T.K.6
Kohno, K.7
Mitra, S.8
Bhakat, K.K.9
-
14
-
-
34250750650
-
Upregulation of dihydropyrimidinase-related protein 2, spectrin alpha II chain, heat shock cognate protein 70 pseudogene 1 and tropomodulin 2 after focal cerebral ischemia in rats-a proteomics approach
-
Chen A, Liao WP, Lu Q, Wong WS, Wong PT. 2007. Upregulation of dihydropyrimidinase-related protein 2, spectrin alpha II chain, heat shock cognate protein 70 pseudogene 1 and tropomodulin 2 after focal cerebral ischemia in rats-a proteomics approach. Neurochem Int 50: 1078-1086.
-
(2007)
Neurochem Int
, vol.50
, pp. 1078-1086
-
-
Chen, A.1
Liao, W.P.2
Lu, Q.3
Wong, W.S.4
Wong, P.T.5
-
15
-
-
0032953308
-
hnRNP H is a component of a splicing enhancer complex that activates a c-src alternative exon in neuronal cells
-
Chou MY, Rooke N, Turck CW, Black DL. 1999. hnRNP H is a component of a splicing enhancer complex that activates a c-src alternative exon in neuronal cells. Mol Cell Biol 19: 69-77.
-
(1999)
Mol Cell Biol
, vol.19
, pp. 69-77
-
-
Chou, M.Y.1
Rooke, N.2
Turck, C.W.3
Black, D.L.4
-
16
-
-
0037835766
-
Mice lacking tropomodulin-2 show enhanced long-term potentiation, hyperactivity, and deficits in learning and memory
-
Cox PR, Fowler V, Xu B, Sweatt JD, Paylor R, Zoghbi HY. 2003. Mice lacking tropomodulin-2 show enhanced long-term potentiation, hyperactivity, and deficits in learning and memory. Mol Cell Neurosci 23: 1-12.
-
(2003)
Mol Cell Neurosci
, vol.23
, pp. 1-12
-
-
Cox, P.R.1
Fowler, V.2
Xu, B.3
Sweatt, J.D.4
Paylor, R.5
Zoghbi, H.Y.6
-
17
-
-
51349110109
-
Enhanced nitrosative stress during Trypanosoma cruzi infection causes nitrotyrosine modification of host proteins: implications in Chagas disease
-
Dhiman M, Nakayasu ES, Madaiah YH, Reynolds BK, Wen JJ, Almeida IC, Garg NJ. 2008. Enhanced nitrosative stress during Trypanosoma cruzi infection causes nitrotyrosine modification of host proteins: implications in Chagas disease. Am J Pathol 173: 728-740.
-
(2008)
Am J Pathol
, vol.173
, pp. 728-740
-
-
Dhiman, M.1
Nakayasu, E.S.2
Madaiah, Y.H.3
Reynolds, B.K.4
Wen, J.J.5
Almeida, I.C.6
Garg, N.J.7
-
18
-
-
0035230130
-
The splice of life: alternative splicing and neurological disease
-
Dredge BK, Polydorides AD, Darnell RB. 2001. The splice of life: alternative splicing and neurological disease. Nat Rev Neurosci 2: 43-50.
-
(2001)
Nat Rev Neurosci
, vol.2
, pp. 43-50
-
-
Dredge, B.K.1
Polydorides, A.D.2
Darnell, R.B.3
-
19
-
-
0032556683
-
APE/Ref-1 responses to ischemia in rat brain
-
Edwards M, Kent TA, Rea HC, Wei J, Quast M, Izumi T, Mitra S, Perez-Polo JR. 1998a. APE/Ref-1 responses to ischemia in rat brain. Neuroreport 9: 4015-4018.
-
(1998)
Neuroreport
, vol.9
, pp. 4015-4018
-
-
Edwards, M.1
Kent, T.A.2
Rea, H.C.3
Wei, J.4
Quast, M.5
Izumi, T.6
Mitra, S.7
Perez-Polo, J.R.8
-
20
-
-
0032402301
-
APE/Ref-1 responses to oxidative stress in aged rats
-
Edwards M, Rassin DK, Izumi T, Mitra S, Perez-Polo JR. 1998b. APE/Ref-1 responses to oxidative stress in aged rats. J Neurosci Res 54: 635-638.
-
(1998)
J Neurosci Res
, vol.54
, pp. 635-638
-
-
Edwards, M.1
Rassin, D.K.2
Izumi, T.3
Mitra, S.4
Perez-Polo, J.R.5
-
21
-
-
0033538343
-
2+ and specific amino acid residues in the catalytic reaction of the major human abasic endonuclease: new insights from EDTA-resistant incision of acyclic abasic site analogs and site-directed mutagenesis
-
2+ and specific amino acid residues in the catalytic reaction of the major human abasic endonuclease: new insights from EDTA-resistant incision of acyclic abasic site analogs and site-directed mutagenesis. J Mol Biol 290: 447-457.
-
(1999)
J Mol Biol
, vol.290
, pp. 447-457
-
-
Erzberger, J.P.1
Wilson 3rd, D.M.2
-
23
-
-
33845967136
-
Tropomodulin 3 binds to actin monomers
-
Fischer RS, Yarmola EG, Weber KL, Speicher KD, Speicher DW, Bubb MR, Fowler VM. 2006. Tropomodulin 3 binds to actin monomers. JBiol Chem 281: 36454-36465.
-
(2006)
JBiol Chem
, vol.281
, pp. 36454-36465
-
-
Fischer, R.S.1
Yarmola, E.G.2
Weber, K.L.3
Speicher, K.D.4
Speicher, D.W.5
Bubb, M.R.6
Fowler, V.M.7
-
24
-
-
49049087691
-
Evolution of the redox function in mammalian apurinic/apyrimidinic endonuclease
-
Georgiadis MM, Luo M, Gaur RK, Delaplane S, Li X, Kelley MR. 2008. Evolution of the redox function in mammalian apurinic/apyrimidinic endonuclease. Mutat Res 643: 54-63.
-
(2008)
Mutat Res
, vol.643
, pp. 54-63
-
-
Georgiadis, M.M.1
Luo, M.2
Gaur, R.K.3
Delaplane, S.4
Li, X.5
Kelley, M.R.6
-
25
-
-
0034906754
-
Alternative RNA splicing in the nervous system
-
Grabowski PJ, Black DL. 2001. Alternative RNA splicing in the nervous system. Prog Neurobiol 65: 289-308.
-
(2001)
Prog Neurobiol
, vol.65
, pp. 289-308
-
-
Grabowski, P.J.1
Black, D.L.2
-
26
-
-
38049112778
-
Early steps in the DNA base excision/single-strand interruption repair pathway in mammalian cells
-
Hegde ML, Hazra TK, Mitra S. 2008. Early steps in the DNA base excision/single-strand interruption repair pathway in mammalian cells. Cell Res 18: 27-47.
-
(2008)
Cell Res
, vol.18
, pp. 27-47
-
-
Hegde, M.L.1
Hazra, T.K.2
Mitra, S.3
-
27
-
-
77953121792
-
The role of Cdk5-mediated apurinic/apyrimidinic endonuclease 1 phosphorylation in neuronal death
-
Huang E, Qu D, Zhang Y, Venderova K, Haque ME, Rousseaux MW, Slack RS, Woulfe JM, Park DS. 2010. The role of Cdk5-mediated apurinic/apyrimidinic endonuclease 1 phosphorylation in neuronal death. Nat Cell Biol 12: 563-571.
-
(2010)
Nat Cell Biol
, vol.12
, pp. 563-571
-
-
Huang, E.1
Qu, D.2
Zhang, Y.3
Venderova, K.4
Haque, M.E.5
Rousseaux, M.W.6
Slack, R.S.7
Woulfe, J.M.8
Park, D.S.9
-
28
-
-
0036275638
-
Alterations in behavior, amyloid β-42, caspase-3, and Cox-2 in mutant PS2 transgenic mouse model of Alzheimer's disease
-
Hwang DY, Chae KR, Kang TS, Hwang JH, Lim CH, Kang HK, Goo JS, Lee MR, Lim HJ, Min SH, Cho JY, Hong JT, Song CW, Paik SG, Cho JS, Kim YK. 2002. Alterations in behavior, amyloid β-42, caspase-3, and Cox-2 in mutant PS2 transgenic mouse model of Alzheimer's disease. FASEB J 16: 805-813.
-
(2002)
FASEB J
, vol.16
, pp. 805-813
-
-
Hwang, D.Y.1
Chae, K.R.2
Kang, T.S.3
Hwang, J.H.4
Lim, C.H.5
Kang, H.K.6
Goo, J.S.7
Lee, M.R.8
Lim, H.J.9
Min, S.H.10
Cho, J.Y.11
Hong, J.T.12
Song, C.W.13
Paik, S.G.14
Cho, J.S.15
Kim, Y.K.16
-
29
-
-
20444490757
-
Analysis of nuclear transport signals in the human apurinic/apyrimidinic endonuclease (APE1/Ref1)
-
Jackson EB, Theriot CA, Chattopadhyay R, Mitra S, Izumi T. 2005. Analysis of nuclear transport signals in the human apurinic/apyrimidinic endonuclease (APE1/Ref1). Nucleic Acids Res 33: 3303-3312.
-
(2005)
Nucleic Acids Res
, vol.33
, pp. 3303-3312
-
-
Jackson, E.B.1
Theriot, C.A.2
Chattopadhyay, R.3
Mitra, S.4
Izumi, T.5
-
30
-
-
0037446328
-
Protective effect of resveratrol on β-amyloid-induced oxidative PC12 cell death
-
Jang JH, Surh YJ. 2003. Protective effect of resveratrol on β-amyloid-induced oxidative PC12 cell death. Free Radic Biol Med 34: 1100-1110.
-
(2003)
Free Radic Biol Med
, vol.34
, pp. 1100-1110
-
-
Jang, J.H.1
Surh, Y.J.2
-
31
-
-
0030900605
-
Identification of redox/repair protein Ref-1 as a potent activator of p53
-
Jayaraman L, Murthy KG, Zhu C, Curran T, Xanthoudakis S, Prives C. 1997. Identification of redox/repair protein Ref-1 as a potent activator of p53. Genes Dev 11: 558-570.
-
(1997)
Genes Dev
, vol.11
, pp. 558-570
-
-
Jayaraman, L.1
Murthy, K.G.2
Zhu, C.3
Curran, T.4
Xanthoudakis, S.5
Prives, C.6
-
32
-
-
70349991252
-
Role of APE1 in differentiated neuroblastoma SH-SY5Y cells in response to oxidative stress: use of APE1 small molecule inhibitors to delineate APE1 functions
-
Jiang Y, Guo C, Fishel ML, Wang ZY, Vasko MR, Kelley MR. 2009. Role of APE1 in differentiated neuroblastoma SH-SY5Y cells in response to oxidative stress: use of APE1 small molecule inhibitors to delineate APE1 functions. DNA Repair 8: 1273-1282.
-
(2009)
DNA Repair
, vol.8
, pp. 1273-1282
-
-
Jiang, Y.1
Guo, C.2
Fishel, M.L.3
Wang, Z.Y.4
Vasko, M.R.5
Kelley, M.R.6
-
33
-
-
70450210313
-
Ape1/Ref-1 stimulates GDNF/GFRalpha1-mediated downstream signaling and neuroblastoma proliferation
-
Kang MY, Kim KY, Yoon Y, Kang Y, Kim HB, Youn CK, Kim DH, Kim MH. 2009. Ape1/Ref-1 stimulates GDNF/GFRalpha1-mediated downstream signaling and neuroblastoma proliferation. Korean J Physiol Pharmacol 13: 349-356.
-
(2009)
Korean J Physiol Pharmacol
, vol.13
, pp. 349-356
-
-
Kang, M.Y.1
Kim, K.Y.2
Yoon, Y.3
Kang, Y.4
Kim, H.B.5
Youn, C.K.6
Kim, D.H.7
Kim, M.H.8
-
34
-
-
0242668337
-
Common structure of soluble amyloid oligomers implies common mechanism of pathogenesis
-
Kayed R, Head E, Thompson JL, McIntire TM, Milton SC, Cotman CW, Glabe CG. 2003. Common structure of soluble amyloid oligomers implies common mechanism of pathogenesis. Science 300: 486-489.
-
(2003)
Science
, vol.300
, pp. 486-489
-
-
Kayed, R.1
Head, E.2
Thompson, J.L.3
McIntire, T.M.4
Milton, S.C.5
Cotman, C.W.6
Glabe, C.G.7
-
35
-
-
64649090347
-
Ape1/Ref-1 induces glial cell-derived neurotropic factor (GDNF) responsiveness by upregulating GDNF receptor alpha1 expression
-
Kim MH, Kim HB, Acharya S, Sohn HM, Jun JY, Chang IY, You HJ. 2009. Ape1/Ref-1 induces glial cell-derived neurotropic factor (GDNF) responsiveness by upregulating GDNF receptor alpha1 expression. Mol Cell Biol 29: 2264-2277.
-
(2009)
Mol Cell Biol
, vol.29
, pp. 2264-2277
-
-
Kim, M.H.1
Kim, H.B.2
Acharya, S.3
Sohn, H.M.4
Jun, J.Y.5
Chang, I.Y.6
You, H.J.7
-
36
-
-
0034979216
-
Oxidative cellular damage and the reduction of APE/Ref-1 expression after experimental traumatic brain injury
-
Lewen A, Sugawara T, Gasche Y, Fujimura M, Chan PH. 2001. Oxidative cellular damage and the reduction of APE/Ref-1 expression after experimental traumatic brain injury. Neurobiol Dis 8: 380-390.
-
(2001)
Neurobiol Dis
, vol.8
, pp. 380-390
-
-
Lewen, A.1
Sugawara, T.2
Gasche, Y.3
Fujimura, M.4
Chan, P.H.5
-
37
-
-
35548940665
-
Neuronal regulation of alternative pre-mRNA splicing
-
Li Q, Lee JA, Black DL. 2007. Neuronal regulation of alternative pre-mRNA splicing. Nat Rev Neurosci 8: 819-831.
-
(2007)
Nat Rev Neurosci
, vol.8
, pp. 819-831
-
-
Li, Q.1
Lee, J.A.2
Black, D.L.3
-
38
-
-
33745236064
-
Membrane associated functions of neurokinin B (NKB) on Aβ (25-35) induced toxicity in aging rat brain synaptosomes
-
Mantha AK, Moorthy K, Cowsik SM, Baquer NZ. 2006a. Membrane associated functions of neurokinin B (NKB) on Aβ (25-35) induced toxicity in aging rat brain synaptosomes. Biogerontology 7: 19-33.
-
(2006)
Biogerontology
, vol.7
, pp. 19-33
-
-
Mantha, A.K.1
Moorthy, K.2
Cowsik, S.M.3
Baquer, N.Z.4
-
39
-
-
33745257258
-
Neuroprotective role of neurokinin B (NKB) on β-amyloid (25-35) induced toxicity in aging rat brain synaptosomes: involvement in oxidative stress and excitotoxicity
-
Mantha AK, Moorthy K, Cowsik SM, Baquer NZ. 2006b. Neuroprotective role of neurokinin B (NKB) on β-amyloid (25-35) induced toxicity in aging rat brain synaptosomes: involvement in oxidative stress and excitotoxicity. Biogerontology 7: 1-17.
-
(2006)
Biogerontology
, vol.7
, pp. 1-17
-
-
Mantha, A.K.1
Moorthy, K.2
Cowsik, S.M.3
Baquer, N.Z.4
-
40
-
-
70350302327
-
APE1/Ref-1 in Alzheimer's disease: an immunohistochemical study
-
Marcon G, Tell G, Perrone L, Garbelli R, Quadrifoglio F, Tagliavini F, Giaccone G. 2009. APE1/Ref-1 in Alzheimer's disease: an immunohistochemical study. Neurosci Lett 466: 124-127.
-
(2009)
Neurosci Lett
, vol.466
, pp. 124-127
-
-
Marcon, G.1
Tell, G.2
Perrone, L.3
Garbelli, R.4
Quadrifoglio, F.5
Tagliavini, F.6
Giaccone, G.7
-
41
-
-
77956216847
-
Mitochondrial and cell death mechanisms in neurodegenerative diseases
-
Martin LJ. 2010. Mitochondrial and cell death mechanisms in neurodegenerative diseases. Pharmaceuticals (Basel) 3: 839-915.
-
(2010)
Pharmaceuticals (Basel)
, vol.3
, pp. 839-915
-
-
Martin, L.J.1
-
42
-
-
0032515143
-
Dynamics of the interaction of human apurinic endonuclease (Ape1) with its substrate and product
-
Masuda Y, Bennett RA, Demple B. 1998. Dynamics of the interaction of human apurinic endonuclease (Ape1) with its substrate and product. J Biol Chem 273: 30352-30359.
-
(1998)
J Biol Chem
, vol.273
, pp. 30352-30359
-
-
Masuda, Y.1
Bennett, R.A.2
Demple, B.3
-
43
-
-
50249176008
-
hnRNP H and hnRNP F complex with Fox2 to silence fibroblast growth factor receptor 2 exon IIIc
-
Mauger DM, Lin C, Garcia-Blanco MA. 2008. hnRNP H and hnRNP F complex with Fox2 to silence fibroblast growth factor receptor 2 exon IIIc. Mol Cell Biol 28: 5403-5419.
-
(2008)
Mol Cell Biol
, vol.28
, pp. 5403-5419
-
-
Mauger, D.M.1
Lin, C.2
Garcia-Blanco, M.A.3
-
44
-
-
0036827988
-
Antioxidants inhibit the human cortical neuron apoptosis induced by hydrogen peroxide, tumor necrosis factor alpha, dopamine and β-amyloid peptide 1-42
-
Medina S, Martinez M, Hernanz A. 2002. Antioxidants inhibit the human cortical neuron apoptosis induced by hydrogen peroxide, tumor necrosis factor alpha, dopamine and β-amyloid peptide 1-42. Free Radic Res 36: 1179-1184.
-
(2002)
Free Radic Res
, vol.36
, pp. 1179-1184
-
-
Medina, S.1
Martinez, M.2
Hernanz, A.3
-
45
-
-
0036628725
-
Choreography of oxidative damage repair in mammalian genomes
-
Mitra S, Izumi T, Boldogh I, Bhakat KK, Hill JW, Hazra TK. 2002. Choreography of oxidative damage repair in mammalian genomes. Free Radic Biol Med 33: 15-28.
-
(2002)
Free Radic Biol Med
, vol.33
, pp. 15-28
-
-
Mitra, S.1
Izumi, T.2
Boldogh, I.3
Bhakat, K.K.4
Hill, J.W.5
Hazra, T.K.6
-
46
-
-
0034719372
-
DNA-bound structures and mutants reveal abasic DNA binding by APE1 and DNA repair coordination [corrected]
-
Mol CD, Izumi T, Mitra S, Tainer JA. 2000. DNA-bound structures and mutants reveal abasic DNA binding by APE1 and DNA repair coordination [corrected]. Nature 403: 451-456.
-
(2000)
Nature
, vol.403
, pp. 451-456
-
-
Mol, C.D.1
Izumi, T.2
Mitra, S.3
Tainer, J.A.4
-
47
-
-
0032567807
-
Mutant AP endonuclease in patients with amyotrophic lateral sclerosis
-
Olkowski ZL. 1998. Mutant AP endonuclease in patients with amyotrophic lateral sclerosis. Neuroreport 9: 239-242.
-
(1998)
Neuroreport
, vol.9
, pp. 239-242
-
-
Olkowski, Z.L.1
-
48
-
-
0029040596
-
Developmental expression of APEX nuclease, a multifunctional DNA repair enzyme, in mouse brains
-
Ono Y, Watanabe M, Inoue Y, Ohmoto T, Akiyama K, Tsutsui K, Seki S. 1995. Developmental expression of APEX nuclease, a multifunctional DNA repair enzyme, in mouse brains. Brain Res Dev Brain Res 86: 1-6.
-
(1995)
Brain Res Dev Brain Res
, vol.86
, pp. 1-6
-
-
Ono, Y.1
Watanabe, M.2
Inoue, Y.3
Ohmoto, T.4
Akiyama, K.5
Tsutsui, K.6
Seki, S.7
-
49
-
-
0037448097
-
Age-related changes in neuronal glucose uptake in response to glutamate and β-amyloid
-
Patel JR, Brewer GJ. 2003. Age-related changes in neuronal glucose uptake in response to glutamate and β-amyloid. J Neurosci Res 72: 527-536.
-
(2003)
J Neurosci Res
, vol.72
, pp. 527-536
-
-
Patel, J.R.1
Brewer, G.J.2
-
50
-
-
80052410726
-
Oxygen resuscitation after hypoxia ischemia stimulates prostaglandin pathway in rat cortex
-
Perez-Polo JR, Reilly CB, Rea HC. 2011. Oxygen resuscitation after hypoxia ischemia stimulates prostaglandin pathway in rat cortex. Int J Dev Neurosci 29: 639-44.
-
(2011)
Int J Dev Neurosci
, vol.29
, pp. 639-644
-
-
Perez-Polo, J.R.1
Reilly, C.B.2
Rea, H.C.3
-
51
-
-
79952009348
-
Differential expression and redox proteomics analyses of an Alzheimer disease transgenic mouse model: effects of the amyloid-β peptide of amyloid precursor protein (Xi)
-
Robinson RA, Lange MB, Sultana R, Galvan V, Fombonne J, Gorostiza O, Zhang J, Warrier G, Cai J, Pierce WM, Bredesen DE, Butterfield DA. 2011. Differential expression and redox proteomics analyses of an Alzheimer disease transgenic mouse model: effects of the amyloid-β peptide of amyloid precursor protein (Xi). Neuroscience 177: 207-222.
-
(2011)
Neuroscience
, vol.177
, pp. 207-222
-
-
Robinson, R.A.1
Lange, M.B.2
Sultana, R.3
Galvan, V.4
Fombonne, J.5
Gorostiza, O.6
Zhang, J.7
Warrier, G.8
Cai, J.9
Pierce, W.M.10
Bredesen, D.E.11
Butterfield, D.A.12
-
52
-
-
0037328721
-
Oxidative damage and reduction of redox factor-1 expression after transient spinal cord ischemia in rabbits
-
Sakurai M, Nagata T, Abe K, Horinouchi T, Itoyama Y, Tabayashi K. 2003. Oxidative damage and reduction of redox factor-1 expression after transient spinal cord ischemia in rabbits. J Vasc Surg 37: 446-452.
-
(2003)
J Vasc Surg
, vol.37
, pp. 446-452
-
-
Sakurai, M.1
Nagata, T.2
Abe, K.3
Horinouchi, T.4
Itoyama, Y.5
Tabayashi, K.6
-
53
-
-
79251647522
-
Human AP endonuclease (APE1/Ref-1) and its acetylation regulate YB-1-p300 recruitment and RNA polymerase II loading in the drug-induced activation of multidrug resistance gene MDR1
-
Sengupta S, Mantha AK, Mitra S, Bhakat KK. 2010. Human AP endonuclease (APE1/Ref-1) and its acetylation regulate YB-1-p300 recruitment and RNA polymerase II loading in the drug-induced activation of multidrug resistance gene MDR1. Oncogene 30: 482-493.
-
(2010)
Oncogene
, vol.30
, pp. 482-493
-
-
Sengupta, S.1
Mantha, A.K.2
Mitra, S.3
Bhakat, K.K.4
-
54
-
-
67749089594
-
Regulation of intracellular calcium in cortical neurons transgenic for human Aβ40 and Aβ42 following nutritive challenge
-
Shirwany NA, Xie J, Guo Q. 2009. Regulation of intracellular calcium in cortical neurons transgenic for human Aβ40 and Aβ42 following nutritive challenge. Int J Clin Exp Med 2: 149-158.
-
(2009)
Int J Clin Exp Med
, vol.2
, pp. 149-158
-
-
Shirwany, N.A.1
Xie, J.2
Guo, Q.3
-
55
-
-
77649251477
-
Apurinic/apyrimidinic endonuclease APE1 is required for PACAP-induced neuroprotection against global cerebral ischemia
-
Stetler RA, Gao Y, Zukin RS, Vosler PS, Zhang L, Zhang F, Cao G, Bennett MV, Chen J. 2010. Apurinic/apyrimidinic endonuclease APE1 is required for PACAP-induced neuroprotection against global cerebral ischemia. Proc Natl Acad Sci U S A 107: 3204-3209.
-
(2010)
Proc Natl Acad Sci U S A
, vol.107
, pp. 3204-3209
-
-
Stetler, R.A.1
Gao, Y.2
Zukin, R.S.3
Vosler, P.S.4
Zhang, L.5
Zhang, F.6
Cao, G.7
Bennett, M.V.8
Chen, J.9
-
56
-
-
37149006484
-
Alterations of some membrane transport proteins in Alzheimer's disease: role of amyloid β-peptide
-
Sultana R, Butterfield DA. 2008. Alterations of some membrane transport proteins in Alzheimer's disease: role of amyloid β-peptide. Mol Biosyst 4: 36-41.
-
(2008)
Mol Biosyst
, vol.4
, pp. 36-41
-
-
Sultana, R.1
Butterfield, D.A.2
-
57
-
-
75149118997
-
Role of oxidative stress in the progression of Alzheimer's disease
-
Sultana R, Butterfield DA. 2010. Role of oxidative stress in the progression of Alzheimer's disease. J Alzheimers Dis 19: 341-353.
-
(2010)
J Alzheimers Dis
, vol.19
, pp. 341-353
-
-
Sultana, R.1
Butterfield, D.A.2
-
58
-
-
33746397535
-
Protective effect of D609 against amyloid-β1-42-induced oxidative modification of neuronal proteins: redox proteomics study
-
Sultana R, Newman SF, Abdul HM, Cai J, Pierce WM, Klein JB, Merchant M, Butterfield DA. 2006. Protective effect of D609 against amyloid-β1-42-induced oxidative modification of neuronal proteins: redox proteomics study. J Neurosci Res 84: 409-417.
-
(2006)
J Neurosci Res
, vol.84
, pp. 409-417
-
-
Sultana, R.1
Newman, S.F.2
Abdul, H.M.3
Cai, J.4
Pierce, W.M.5
Klein, J.B.6
Merchant, M.7
Butterfield, D.A.8
-
59
-
-
67349253085
-
Oxidatively modified proteins in Alzheimer's disease (AD), mild cognitive impairment and animal models of AD: role of Aβ in pathogenesis
-
Sultana R, Perluigi M, Butterfield DA. 2009. Oxidatively modified proteins in Alzheimer's disease (AD), mild cognitive impairment and animal models of AD: role of Aβ in pathogenesis. Acta Neuropathol 118: 131-150.
-
(2009)
Acta Neuropathol
, vol.118
, pp. 131-150
-
-
Sultana, R.1
Perluigi, M.2
Butterfield, D.A.3
-
60
-
-
0027137461
-
Tropomodulin is highly concentrated at the postsynaptic domain of human and rat neuromuscular junctions
-
Sussman MA, Bilak M, Kedes L, Engel WK, Askanas V. 1993. Tropomodulin is highly concentrated at the postsynaptic domain of human and rat neuromuscular junctions. Exp Cell Res 209: 388-391.
-
(1993)
Exp Cell Res
, vol.209
, pp. 388-391
-
-
Sussman, M.A.1
Bilak, M.2
Kedes, L.3
Engel, W.K.4
Askanas, V.5
-
61
-
-
0032563635
-
Immunohistochemical localization of redox factor-1 (Ref-1) in Alzheimer's hippocampus
-
Tan Z, Sun N, Schreiber SS. 1998. Immunohistochemical localization of redox factor-1 (Ref-1) in Alzheimer's hippocampus. Neuroreport 9: 2749-2752.
-
(1998)
Neuroreport
, vol.9
, pp. 2749-2752
-
-
Tan, Z.1
Sun, N.2
Schreiber, S.S.3
-
62
-
-
77951831100
-
Differential expression of redox factor-1 associated with β-amyloid-mediated neurotoxicity
-
Tan Z, Shi L, Schreiber SS. 2009. Differential expression of redox factor-1 associated with β-amyloid-mediated neurotoxicity. Open Neurosci J 3: 26-34.
-
(2009)
Open Neurosci J
, vol.3
, pp. 26-34
-
-
Tan, Z.1
Shi, L.2
Schreiber, S.S.3
-
64
-
-
0037010293
-
Attenuated transcriptional responses to oxidative stress in the aged rat brain
-
Tong L, Toliver-Kinsky T, Edwards M, Rassin DK, Werrbach-Perez K, Perez-Polo JR. 2002. Attenuated transcriptional responses to oxidative stress in the aged rat brain. J Neurosci Res 70: 318-326.
-
(2002)
J Neurosci Res
, vol.70
, pp. 318-326
-
-
Tong, L.1
Toliver-Kinsky, T.2
Edwards, M.3
Rassin, D.K.4
Werrbach-Perez, K.5
Perez-Polo, J.R.6
-
65
-
-
61549109882
-
Genome-wide analysis and proteomic studies reveal APE1/Ref-1 multifunctional role in mammalian cells
-
Vascotto C, Cesaratto L, Zeef LA, Deganuto M, D'Ambrosio C, Scaloni A, Romanello M, Damante G, Taglialatela G, Delneri D, Kelley MR, Mitra S, Quadrifoglio F, Tell G. 2009a. Genome-wide analysis and proteomic studies reveal APE1/Ref-1 multifunctional role in mammalian cells. Proteomics 9: 1058-1074.
-
(2009)
Proteomics
, vol.9
, pp. 1058-1074
-
-
Vascotto, C.1
Cesaratto, L.2
Zeef, L.A.3
Deganuto, M.4
D'Ambrosio, C.5
Scaloni, A.6
Romanello, M.7
Damante, G.8
Taglialatela, G.9
Delneri, D.10
Kelley, M.R.11
Mitra, S.12
Quadrifoglio, F.13
Tell, G.14
-
66
-
-
63049121360
-
APE1/Ref-1 interacts with NPM1 within nucleoli and plays a role in the rRNA quality control process
-
Vascotto C, Fantini D, Romanello M, Cesaratto L, Deganuto M, Leonardi A, Radicella JP, Kelley MR, D'Ambrosio C, Scaloni A, Quadrifoglio F, Tell G. 2009b. APE1/Ref-1 interacts with NPM1 within nucleoli and plays a role in the rRNA quality control process. Mol Cell Biol 29: 1834-1854.
-
(2009)
Mol Cell Biol
, vol.29
, pp. 1834-1854
-
-
Vascotto, C.1
Fantini, D.2
Romanello, M.3
Cesaratto, L.4
Deganuto, M.5
Leonardi, A.6
Radicella, J.P.7
Kelley, M.R.8
D'Ambrosio, C.9
Scaloni, A.10
Quadrifoglio, F.11
Tell, G.12
-
67
-
-
12344291209
-
The multifunctional DNA repair/redox enzyme Ape1/Ref-1 promotes survival of neurons after oxidative stress
-
Vasko MR, Guo C, Kelley MR. 2005. The multifunctional DNA repair/redox enzyme Ape1/Ref-1 promotes survival of neurons after oxidative stress. DNA Repair 4: 367-379.
-
(2005)
DNA Repair
, vol.4
, pp. 367-379
-
-
Vasko, M.R.1
Guo, C.2
Kelley, M.R.3
-
68
-
-
0031036811
-
Loss of Ref-1 protein expression precedes DNA fragmentation in apoptotic neurons
-
Walton M, Lawlor P, Sirimanne E, Williams C, Gluckman P, Dragunow M. 1997. Loss of Ref-1 protein expression precedes DNA fragmentation in apoptotic neurons. Brain Res Mol Brain Res 44: 167-170.
-
(1997)
Brain Res Mol Brain Res
, vol.44
, pp. 167-170
-
-
Walton, M.1
Lawlor, P.2
Sirimanne, E.3
Williams, C.4
Gluckman, P.5
Dragunow, M.6
-
69
-
-
0030004546
-
Differential expression of the apurinic/apyrimidinic endonuclease (APE/ref-1) multifunctional DNA base excision repair gene during fetal development and in adult rat brain and testis
-
Wilson TM, Rivkees SA, Deutsch WA, Kelley MR. 1996. Differential expression of the apurinic/apyrimidinic endonuclease (APE/ref-1) multifunctional DNA base excision repair gene during fetal development and in adult rat brain and testis. Mutat Res 362: 237-248.
-
(1996)
Mutat Res
, vol.362
, pp. 237-248
-
-
Wilson, T.M.1
Rivkees, S.A.2
Deutsch, W.A.3
Kelley, M.R.4
-
70
-
-
0026583944
-
Identification and characterization of Ref-1, a nuclear protein that facilitates AP-1 DNA-binding activity
-
Xanthoudakis S, Curran T. 1992. Identification and characterization of Ref-1, a nuclear protein that facilitates AP-1 DNA-binding activity. EMBO J 11: 653-665.
-
(1992)
EMBO J
, vol.11
, pp. 653-665
-
-
Xanthoudakis, S.1
Curran, T.2
-
71
-
-
77957747467
-
Mammalian tropomodulins nucleate actin polymerization via their actin monomer binding and filament pointed end-capping activities
-
Yamashiro S, Speicher KD, Speicher DW, Fowler VM. 2010. Mammalian tropomodulins nucleate actin polymerization via their actin monomer binding and filament pointed end-capping activities. J Biol Chem 285: 33265-33280.
-
(2010)
J Biol Chem
, vol.285
, pp. 33265-33280
-
-
Yamashiro, S.1
Speicher, K.D.2
Speicher, D.W.3
Fowler, V.M.4
-
72
-
-
77956257886
-
Neurons efficiently repair glutamate-induced oxidative DNA damage by a process involving CREB-mediated upregulation of apurinic endonuclease 1
-
Yang JL, Tadokoro T, Keijzers G, Mattson MP, Bohr VA. 2010. Neurons efficiently repair glutamate-induced oxidative DNA damage by a process involving CREB-mediated upregulation of apurinic endonuclease 1. J Biol Chem 285: 28191-28199.
-
(2010)
J Biol Chem
, vol.285
, pp. 28191-28199
-
-
Yang, J.L.1
Tadokoro, T.2
Keijzers, G.3
Mattson, M.P.4
Bohr, V.A.5
-
73
-
-
0024990330
-
Neurotrophic and neurotoxic effects of amyloid β protein: reversal by tachykinin neuropeptides
-
Yankner BA, Duffy LK, Kirschner DA. 1990. Neurotrophic and neurotoxic effects of amyloid β protein: reversal by tachykinin neuropeptides. Science 250: 279-282.
-
(1990)
Science
, vol.250
, pp. 279-282
-
-
Yankner, B.A.1
Duffy, L.K.2
Kirschner, D.A.3
-
74
-
-
51049091691
-
Small-molecule inhibitor of the AP endonuclease 1/REF-1 E3330 inhibits pancreatic cancer cell growth and migration
-
Zou GM, Maitra A. 2008. Small-molecule inhibitor of the AP endonuclease 1/REF-1 E3330 inhibits pancreatic cancer cell growth and migration. Mol Cancer Ther 7: 2012-2021.
-
(2008)
Mol Cancer Ther
, vol.7
, pp. 2012-2021
-
-
Zou, G.M.1
Maitra, A.2
-
75
-
-
60849127593
-
The Ape-1/Ref-1 redox antagonist E3330 inhibits the growth of tumor endothelium and endothelial progenitor cells: therapeutic implications in tumor angiogenesis
-
Zou GM, Karikari C, Kabe Y, Handa H, Anders RA, Maitra A. 2009. The Ape-1/Ref-1 redox antagonist E3330 inhibits the growth of tumor endothelium and endothelial progenitor cells: therapeutic implications in tumor angiogenesis. J Cell Physiol 219: 209-218.
-
(2009)
J Cell Physiol
, vol.219
, pp. 209-218
-
-
Zou, G.M.1
Karikari, C.2
Kabe, Y.3
Handa, H.4
Anders, R.A.5
Maitra, A.6
|