Genetic polymorphisms in APE1 are associated with renal cell carcinoma risk in a Chinese population

Molecular Carcinogenesis

Volumn 50, Issue 11, 2011, Pages 863-870

  Cao, Qiang ^a   Qin, Chao ^a   Meng, Xiaoxin ^a   Ju, Xiaobing ^a   Ding, Qi ^a   Wang, Meilin ^b   Zhu, Jian ^a   Wang, Wei ^b   Li, Pu ^a   Chen, Jiawei ^a   Zhang, Zhengdong ^b   Yin, Changjun ^a  

^a THE FIRST AFFILIATED HOSPITAL OF NANJING MEDICAL UNIVERSITY   (China)

^b NANJING MEDICAL UNIVERSITY   (China)

Author keywords

APE1; Renal cell carcinoma; Single nucleotide polymorphism

Indexed keywords

APYRIMIDINIC ENDONUCLEASE 1; NUCLEAR PROTEIN; UNCLASSIFIED DRUG;

ADULT; ARTICLE; BODY MASS; CANCER RISK; CANCER STAGING; CASE CONTROL STUDY; CHINESE; CONTROLLED STUDY; DRINKING BEHAVIOR; FEMALE; GENETIC ASSOCIATION; GENETIC VARIABILITY; GENOTYPE; HUMAN; KIDNEY CARCINOMA; MAJOR CLINICAL STUDY; MALE; PRIORITY JOURNAL; SINGLE NUCLEOTIDE POLYMORPHISM; SMOKING;

AGED; ASIAN CONTINENTAL ANCESTRY GROUP; CARCINOMA, RENAL CELL; CASE-CONTROL STUDIES; DNA REPAIR; DNA-(APURINIC OR APYRIMIDINIC SITE) LYASE; FEMALE; GENETIC PREDISPOSITION TO DISEASE; HUMANS; MALE; MIDDLE AGED; POLYMORPHISM, SINGLE NUCLEOTIDE;

EID: 80054763444     PISSN: 08991987     EISSN: 10982744     Source Type: Journal    
DOI: 10.1002/mc.20791     Document Type: Article

References (34)

1. Jemal A, Siegel R, Ward E, Hao Y, Xu J, Thun MJ. Cancer statistics, 2009. CA Cancer J Clin 2009;59:225-249.
2. Lipworth L, Tarone RE, McLaughlin JK. The epidemiology of renal cell carcinoma. J Urol 2006;176:2353-2358.
3. Chow WH, Dong LM, Devesa SS. Epidemiology and risk factors for kidney cancer. Nat Rev Urol 2010;7:245-257.
4. Wood RD, Mitchell M, Lindahl T. Human DNA repair genes, 2005. Mutat Res 2005;577:275-283.
5. Wilson DM III, Bohr VA. The mechanics of base excision repair, and its relationship to aging and disease. DNA Repair (Amst) 2007;6:544-559.
6. Hoeijmakers JH. Genome maintenance mechanisms for preventing cancer. Nature 2001;411:366-374.
7. Barzilay G, Hickson ID. Structure and function of apurinic/apyrimidinic endonucleases. Bioessays 1995;17:713-719.
8. Izumi T, Hazra TK, Boldogh I, et al. Requirement for human AP endonuclease 1 for repair of 3'-blocking damage at DNA single-strand breaks induced by reactive oxygen species. Carcinogenesis 2000;21:1329-1334.
9. Fortini P, Pascucci B, Parlanti E, D'Errico M, Simonelli V, Dogliotti E. The base excision repair: Mechanisms and its relevance for cancer susceptibility. Biochimie 2003;85:1053-1071.
10. Tudek B. Base excision repair modulation as a risk factor for human cancers. Mol Aspects Med 2007;28:258-275.
11. Vineis P, Manuguerra M, Kavvoura FK, et al. A field synopsis on low-penetrance variants in DNA repair genes and cancer susceptibility. J Natl Cancer Inst 2009;101:24-36.
12. Xi T, Jones IM, Mohrenweiser HW. Many amino acid substitution variants identified in DNA repair genes during human population screenings are predicted to impact protein function. Genomics 2004;83:970-979.
13. Gu D, Wang M, Zhang Z, Chen J. The DNA repair gene APE1 T1349G polymorphism and cancer risk: A meta-analysis of 27 case-control studies. Mutagenesis 2009;24:507-512.
14. Lo YL, Jou YS, Hsiao CF, et al. A polymorphism in the APE1 gene promoter is associated with lung cancer risk. Cancer Epidemiol Biomarkers Prev 2009;18:223-229.
15. Lu J, Zhang S, Chen D, et al. Functional characterization of a promoter polymorphism in APE1/Ref-1 that contributes to reduced lung cancer susceptibility. FASEB J 2009;23:3459-3469.
16. Hirata H, Hinoda Y, Matsuyama H, et al. Polymorphisms of DNA repair genes are associated with renal cell carcinoma. Biochem Biophys Res Commun 2006;342:1058-1062.
17. Sakano S, Hinoda Y, Okayama N, et al. The association of DNA repair gene polymorphisms with the development and progression of renal cell carcinoma. Ann Oncol 2007;18:1817-1827.
18. Lin J, Pu X, Wang W, et al. Case-control analysis of nucleotide excision repair pathway and the risk of renal cell carcinoma. Carcinogenesis 2008;29:2112-2119.
19. Zhu J, Qin C, Wang M, et al. Functional polymorphisms in cell death pathway genes and risk of renal cell carcinoma. Mol Carcinog 2010;49:810-817.
20. Lindahl T. Recognition and processing of damaged DNA. J Cell Sci Suppl 1995;19:73-77.
21. Hadi MZ, Coleman MA, Fidelis K, Mohrenweiser HW, Wilson DM III. Functional characterization of Ape1 variants identified in the human population. Nucleic Acids Res 2000;28:3871-3879.
22. Au WW, Salama SA, Sierra-Torres CH. Functional characterization of polymorphisms in DNA repair genes using cytogenetic challenge assays. Environ Health Perspect 2003;111:1843-1850.
23. Maslov AY, Vijg J. Genome instability, cancer and aging. Biochim Biophys Acta 2009;1790:963-969.
24. Vijg J, Busuttil RA, Bahar R, Dolle ME. Aging and genome maintenance. Ann N Y Acad Sci 2005;1055:35-47.
25. Terry PD, Umbach DM, Taylor JA. APE1 genotype and risk of bladder cancer: Evidence for effect modification by smoking. Int J Cancer 2006;118:3170-3173.
26. Hazra A, Chamberlain RM, Grossman HB, Zhu Y, Spitz MR, Wu X. Death receptor 4 and bladder cancer risk. Cancer Res 2003;63:1157-1159.
27. McLaughlin JK, Lipworth L. Epidemiologic aspects of renal cell cancer. Semin Oncol 2000;27:115-123.
28. Bergstrom A, Hsieh CC, Lindblad P, Lu CM, Cook NR, Wolk A. Obesity and renal cell cancer - a quantitative review. Br J Cancer 2001;85:984-990.
29. Rundle A, Madsen A, Orjuela M, et al. The association between benzo[a]pyrene-DNA adducts and body mass index, calorie intake and physical activity. Biomarkers 2007;12:123-132.
30. Calle EE, Kaaks R. Overweight, obesity and cancer: Epidemiological evidence and proposed mechanisms. Nat Rev Cancer 2004;4:579-591.
31. Mason JB, Choi SW. Effects of alcohol on folate metabolism: Implications for carcinogenesis. Alcohol 2005;35:235-241.
32. Tao MH, Marian C, Shields PG, et al. Alcohol consumption in relation to aberrant DNA methylation in breast tumors. Alcohol. DOI: 10.1016/j.alcohol.2010.11.006.
33. Hao B, Wang H, Zhou K, et al. Identification of genetic variants in base excision repair pathway and their associations with risk of esophageal squamous cell carcinoma. Cancer Res 2004;64:4378-4384.
34. Huang WY, Gao YT, Rashid A, et al. Selected base excision repair gene polymorphisms and susceptibility to biliary tract cancer and biliary stones: A population-based case-control study in China. Carcinogenesis 2008;29:100-105.