Molecular mechanisms of transcription activation by HLF and HIF1α in response to hypoxia: Their stabilization and redox signal-induced interaction with CBP/p300

EMBO Journal

Volumn 18, Issue 7, 1999, Pages 1905-1914

  Ema, Masatsugu ^d   Hirota, Kiichi ^a   Mimura, Junsei ^d   Abe, Hisaku ^d   Yodoi, Junji ^b   Sogawa, Kazuhiro ^d   Poellinger, Lorenz ^c   Fujii Kuriyama, Yoshiaki ^d  

^a KYOTO UNIVERSITY HOSPITAL   (Japan)

^b KYOTO UNIVERSITY   (Japan)

^c KAROLINSKA INSTITUTE   (Sweden)

^d TOHOKU UNIVERSITY   (Japan)

Author keywords

Oxygen sensing; Protein stabilization; Redox regulation; Sulfhydryl modification; Thioredoxin

Indexed keywords

BETA GALACTOSIDASE; CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN; CYSTEINE; HYPOXIA INDUCIBLE FACTOR 1ALPHA; LUCIFERASE; OXYGEN; THIOREDOXIN; TRANSCRIPTION FACTOR; UNCLASSIFIED DRUG;

AMINO ACID SUBSTITUTION; AMINO TERMINAL SEQUENCE; ARTICLE; CARBOXY TERMINAL SEQUENCE; CONTROLLED STUDY; DNA SEQUENCE; DNA TRANSFECTION; FUSION GENE; GENE INDUCTION; HUMAN; HUMAN CELL; HYPOXIA; IMMUNOBLOTTING; OXIDATION REDUCTION REACTION; PRIORITY JOURNAL; PROTEIN PROTEIN INTERACTION; PROTEIN STABILITY; PROTEIN TRANSPORT; REPORTER GENE; STRUCTURE ACTIVITY RELATION; TRANSCRIPTION REGULATION; YEAST;

AMINO ACID SEQUENCE; BASE SEQUENCE; BASIC HELIX-LOOP-HELIX TRANSCRIPTION FACTORS; CARBON-OXYGEN LYASES; CELL HYPOXIA; CELL LINE; DNA PRIMERS; DNA-(APURINIC OR APYRIMIDINIC SITE) LYASE; DNA-BINDING PROTEINS; DRUG STABILITY; HELA CELLS; HUMANS; HYPOXIA-INDUCIBLE FACTOR 1; HYPOXIA-INDUCIBLE FACTOR 1, ALPHA SUBUNIT; MODELS, BIOLOGICAL; MOLECULAR SEQUENCE DATA; NUCLEAR PROTEINS; OXIDATION-REDUCTION; SIGNAL TRANSDUCTION; THIOREDOXIN; TRANS-ACTIVATION (GENETICS); TRANS-ACTIVATORS; TRANSCRIPTION FACTORS; TRANSFECTION;

MAMMALIA;

EID: 0033118983     PISSN: 02614189     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

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