-
1
-
-
0025077481
-
Redox regulation of fos and jun DNA-binding activity in vitro
-
Abate, C., L. Patel, F. J. Rauscher III, and T. Curran. 1990. Redox regulation of fos and jun DNA-binding activity in vitro. Science 249:1157-1161.
-
(1990)
Science
, vol.249
, pp. 1157-1161
-
-
Abate, C.1
Patel, L.2
Rauscher III, F.J.3
Curran, T.4
-
2
-
-
0036581222
-
The GDNF family: Signalling, biological functions and therapeutic value
-
Airaksinen, M. S., and M. Saarma. 2002. The GDNF family: signalling, biological functions and therapeutic value. Nat. Rev. Neurosci. 3:383-394.
-
(2002)
Nat. Rev. Neurosci
, vol.3
, pp. 383-394
-
-
Airaksinen, M.S.1
Saarma, M.2
-
3
-
-
0033023140
-
GDNF family neu-rotrophic factor signaling: Four masters, one servant?
-
Airaksinen, M. S., A. Titievsky, and M. Saarma. 1999. GDNF family neu-rotrophic factor signaling: four masters, one servant? Mol. Cell Neurosci. 13:313-325.
-
(1999)
Mol. Cell Neurosci
, vol.13
, pp. 313-325
-
-
Airaksinen, M.S.1
Titievsky, A.2
Saarma, M.3
-
4
-
-
48349107170
-
A new APE1/Ref-1-dependent pathway leading to reduction of NF-κB and AP-1, and activation of their DNA-binding activity
-
Ando, K., S. Hirao, Y. Kabe, Y. Ogura, I. Sato, Y. Yamaguchi, T. Wada, and H. Handa. 2008. A new APE1/Ref-1-dependent pathway leading to reduction of NF-κB and AP-1, and activation of their DNA-binding activity. Nucleic Acids Res. 36:4327-4336.
-
(2008)
Nucleic Acids Res
, vol.36
, pp. 4327-4336
-
-
Ando, K.1
Hirao, S.2
Kabe, Y.3
Ogura, Y.4
Sato, I.5
Yamaguchi, Y.6
Wada, T.7
Handa, H.8
-
5
-
-
0032408664
-
-
Baloh, R. H., M. G. Tansey, P. A, Lampe, T. J. Fahrner, H. Enomoto, K. S. Simburger, M. L. Leitner, T. Araki, E. M. Johnson, Jr., and J. Milbrandt. 1998. Artemin, a novel member of the GDNF ligand family, supports peripheral and central neurons and signals through the GFRα3-RET receptor complex. Neuron 21:1291-1302.
-
Baloh, R. H., M. G. Tansey, P. A, Lampe, T. J. Fahrner, H. Enomoto, K. S. Simburger, M. L. Leitner, T. Araki, E. M. Johnson, Jr., and J. Milbrandt. 1998. Artemin, a novel member of the GDNF ligand family, supports peripheral and central neurons and signals through the GFRα3-RET receptor complex. Neuron 21:1291-1302.
-
-
-
-
6
-
-
0347504848
-
Role of acetylated human AP-endonuclease (APE1/Ref-1) in regulation of the parathyroid hormone gene
-
Bhakat, K. K., T. Izumi, S. H. Yang, T. K. Hazra, and S. Mitra. 2003. Role of acetylated human AP-endonuclease (APE1/Ref-1) in regulation of the parathyroid hormone gene. EMBO J. 22:6299-6309.
-
(2003)
EMBO J
, vol.22
, pp. 6299-6309
-
-
Bhakat, K.K.1
Izumi, T.2
Yang, S.H.3
Hazra, T.K.4
Mitra, S.5
-
7
-
-
0035176178
-
Apurinic/apyrimidinic endonuclease activity is elevated in human adult gliomas
-
Bobola, M. S., A. Blank, M. S. Berger, B. A. Stevens, and J. R. Silber. 2001. Apurinic/apyrimidinic endonuclease activity is elevated in human adult gliomas. Clin. Cancer Res. 7:3510-3518.
-
(2001)
Clin. Cancer Res
, vol.7
, pp. 3510-3518
-
-
Bobola, M.S.1
Blank, A.2
Berger, M.S.3
Stevens, B.A.4
Silber, J.R.5
-
8
-
-
0028359164
-
Interaction of pancreatic ductal carcinoma with nerves leads to nerve damage
-
Bockman, D. E., M. Buchler, and H. G. Beger. 1994. Interaction of pancreatic ductal carcinoma with nerves leads to nerve damage. Gastroenter-ology 107:219-230.
-
(1994)
Gastroenter-ology
, vol.107
, pp. 219-230
-
-
Bockman, D.E.1
Buchler, M.2
Beger, H.G.3
-
9
-
-
0030925220
-
Neurturin responsiveness requires a GPI-linked receptor and the Ret receptor tyrosine kinase
-
Buj-Bello, A., J. Adu, L. G. Pinon, A Horton, J. Thompson, A. Rosenthal, M. Chinchetru, V. L. Buchman, and A. M. Davies. 1997. Neurturin responsiveness requires a GPI-linked receptor and the Ret receptor tyrosine kinase. Nature 387:721-724.
-
(1997)
Nature
, vol.387
, pp. 721-724
-
-
Buj-Bello, A.1
Adu, J.2
Pinon, L.G.3
Horton, A.4
Thompson, J.5
Rosenthal, A.6
Chinchetru, M.7
Buchman, V.L.8
Davies, A.M.9
-
10
-
-
0033986948
-
Redox-regulated recruitment of the transcriptional coac-tivators CREB-binding protein and SRC-1 to hypoxia-inducible factor 1al-pha
-
Carrero, P., K. Okamoto, P. Coumailleau, S. O'Brien, H. Tanaka, and L. Poellinger. 2000. Redox-regulated recruitment of the transcriptional coac-tivators CREB-binding protein and SRC-1 to hypoxia-inducible factor 1al-pha. Mol. Cell. Biol. 20:402-415.
-
(2000)
Mol. Cell. Biol
, vol.20
, pp. 402-415
-
-
Carrero, P.1
Okamoto, K.2
Coumailleau, P.3
O'Brien, S.4
Tanaka, H.5
Poellinger, L.6
-
11
-
-
57349170258
-
Regulatory role of human AP-endonuclease (APE1/Ref-1) in YB-1-mediated activation of the multi-drug resistance gene MDR1
-
Chattopadhyay, R., S. Das, A. K. Maiti, I. Boldogh, J. Xie, T. K. Hazra, K. Kohno, S. Mitra, and K. K. Bhakat. 2008. Regulatory role of human AP-endonuclease (APE1/Ref-1) in YB-1-mediated activation of the multi-drug resistance gene MDR1. Mol. Cell. Biol. 28:7066-7080.
-
(2008)
Mol. Cell. Biol
, vol.28
, pp. 7066-7080
-
-
Chattopadhyay, R.1
Das, S.2
Maiti, A.K.3
Boldogh, I.4
Xie, J.5
Hazra, T.K.6
Kohno, K.7
Mitra, S.8
Bhakat, K.K.9
-
12
-
-
0026004662
-
Two distinct human DNA diesterases that hydrolyze 3'-blocking deoxyribose fragments from oxidized DNA
-
Chen, D. S., T. Herman, and B. Demple. 1991. Two distinct human DNA diesterases that hydrolyze 3'-blocking deoxyribose fragments from oxidized DNA. Nucleic Acids Res. 19:5907-5914.
-
(1991)
Nucleic Acids Res
, vol.19
, pp. 5907-5914
-
-
Chen, D.S.1
Herman, T.2
Demple, B.3
-
13
-
-
0034027636
-
Evidence that the bifunctional redox factor/AP endonuclease Ref-1 is an antiapop-totic protein associated with differentiation in the developing retina
-
Chiarini, L. B., F. G. Freitas, H. Petrs-Silva, and R. Linden. 2000. Evidence that the bifunctional redox factor/AP endonuclease Ref-1 is an antiapop-totic protein associated with differentiation in the developing retina. Cell Death Differ. 7:272-281.
-
(2000)
Cell Death Differ
, vol.7
, pp. 272-281
-
-
Chiarini, L.B.1
Freitas, F.G.2
Petrs-Silva, H.3
Linden, R.4
-
14
-
-
15844387271
-
The interaction between Ku antigen and REF1 protein mediates negative gene regulation by extracellular calcium
-
Chung, U., T. Igarashi, T. Nishishita, H. Iwanari, A. Iwamatsu, A. Suwa, T. Mimori, K. Hata, S. Ebisu, E. Ogata, T. Fujita, and T. Okazaki. 1996. The interaction between Ku antigen and REF1 protein mediates negative gene regulation by extracellular calcium. J. Biol. Chem. 271:8593-8598.
-
(1996)
J. Biol. Chem
, vol.271
, pp. 8593-8598
-
-
Chung, U.1
Igarashi, T.2
Nishishita, T.3
Iwanari, H.4
Iwamatsu, A.5
Suwa, A.6
Mimori, T.7
Hata, K.8
Ebisu, S.9
Ogata, E.10
Fujita, T.11
Okazaki, T.12
-
15
-
-
0037127194
-
Coordinated activation of autophosphorylation sites in the RET receptor tyrosine kinase: Importance of tyrosine 1062 for GDNF mediated neuronal differentiation and survival
-
Coulpier, M., J. Anders, and C. F. Ibanez. 2002. Coordinated activation of autophosphorylation sites in the RET receptor tyrosine kinase: importance of tyrosine 1062 for GDNF mediated neuronal differentiation and survival. J. Biol. Chem. 277:1991-1999.
-
(2002)
J. Biol. Chem
, vol.277
, pp. 1991-1999
-
-
Coulpier, M.1
Anders, J.2
Ibanez, C.F.3
-
16
-
-
0028342951
-
Repair of oxidative damage to DNA: Enzymology and biology
-
Demple, B., and L. Harrison. 1994. Repair of oxidative damage to DNA: enzymology and biology. Annu. Rev. Biochem. 63:915-948.
-
(1994)
Annu. Rev. Biochem
, vol.63
, pp. 915-948
-
-
Demple, B.1
Harrison, L.2
-
17
-
-
0032402301
-
APE/Ref-1 responses to oxidative stress in aged rats
-
Edwards, M, D. K. Rassin, T. Izumi, S. Mitra, and J. R. Perez-Polo. 1998. APE/Ref-1 responses to oxidative stress in aged rats. J. Neurosci. Res. 54:635-638.
-
(1998)
J. Neurosci. Res
, vol.54
, pp. 635-638
-
-
Edwards, M.1
Rassin, D.K.2
Izumi, T.3
Mitra, S.4
Perez-Polo, J.R.5
-
18
-
-
0033118983
-
Molecular mechanisms of transcription activation by HLF and HIF1α in response to hypoxia: Their stabilization and redox signal-induced interaction with CBP/p300
-
Ema, M, K. Hirota, J. Mimura, H. Abe, J. Yodoi, K. Sogawa, L. Poellinger, and Y. Fujii-Kuriyama. 1999. Molecular mechanisms of transcription activation by HLF and HIF1α in response to hypoxia: their stabilization and redox signal-induced interaction with CBP/p300. EMBO J. 18:1905-1914.
-
(1999)
EMBO J
, vol.18
, pp. 1905-1914
-
-
Ema, M.1
Hirota, K.2
Mimura, J.3
Abe, H.4
Yodoi, J.5
Sogawa, K.6
Poellinger, L.7
Fujii-Kuriyama, Y.8
-
19
-
-
0032504961
-
-
Enokido, Y., F. de Sauvage, J. A, Hongo, N. Ninkina, A, Rosenthal, V. L. Buchman, and A. M. Davies. 1998. GFRa-4 and the tyrosine kinase Ret form a functional receptor complex for persephin. Curr. Biol. 8:1019-1022.
-
Enokido, Y., F. de Sauvage, J. A, Hongo, N. Ninkina, A, Rosenthal, V. L. Buchman, and A. M. Davies. 1998. GFRa-4 and the tyrosine kinase Ret form a functional receptor complex for persephin. Curr. Biol. 8:1019-1022.
-
-
-
-
21
-
-
37549033163
-
Knockdown of the DNA repair and redox signaling protein Ape1/Ref-1 blocks ovarian cancer cell and tumor growth
-
Fishel, M. L., Y. He, A. M. Reed, H. Chin-Sinex, G. D. Hutchins, M. S. Mendonca, and M. R. Kelley. 2008. Knockdown of the DNA repair and redox signaling protein Ape1/Ref-1 blocks ovarian cancer cell and tumor growth. DNA Repair 7:177-186.
-
(2008)
DNA Repair
, vol.7
, pp. 177-186
-
-
Fishel, M.L.1
He, Y.2
Reed, A.M.3
Chin-Sinex, H.4
Hutchins, G.D.5
Mendonca, M.S.6
Kelley, M.R.7
-
22
-
-
0142219356
-
Studies of apurinic/apyrimidinic endonuclease/ref-1 expression in epithelial ovarian cancer: Correlations with tumor progression and platinum resistance
-
Freitas, S, D. H. Moore, H. Michael, and M. R. Kelley. 2003. Studies of apurinic/apyrimidinic endonuclease/ref-1 expression in epithelial ovarian cancer: correlations with tumor progression and platinum resistance. Clin. Cancer Res. 9:4689-4694.
-
(2003)
Clin. Cancer Res
, vol.9
, pp. 4689-4694
-
-
Freitas, S.1
Moore, D.H.2
Michael, H.3
Kelley, M.R.4
-
23
-
-
0033740986
-
Human APE/Ref-1 protein
-
Fritz, G. 2000. Human APE/Ref-1 protein. Int. J. Biochem. Cell Biol. 32:925-929.
-
(2000)
Int. J. Biochem. Cell Biol
, vol.32
, pp. 925-929
-
-
Fritz, G.1
-
24
-
-
0242299711
-
APE/Ref-1 and the mammalian response to genotoxic stress
-
Fritz, G., S. Grosch, M. Tomicic, and B. Kaina. 2003. APE/Ref-1 and the mammalian response to genotoxic stress. Toxicology 193:67-78.
-
(2003)
Toxicology
, vol.193
, pp. 67-78
-
-
Fritz, G.1
Grosch, S.2
Tomicic, M.3
Kaina, B.4
-
25
-
-
0033611583
-
Phosphorylation of the DNA repair protein APE/REF-1 by CKII affects redox regulation of AP-1
-
Fritz, G., and B. Kaina. 1999. Phosphorylation of the DNA repair protein APE/REF-1 by CKII affects redox regulation of AP-1. Oncogene 18:1033-1040.
-
(1999)
Oncogene
, vol.18
, pp. 1033-1040
-
-
Fritz, G.1
Kaina, B.2
-
26
-
-
0037331196
-
Implication of Ref-1 in the repression of renin gene transcription by intracellular calcium
-
Fuchs, S., J. Philippe, P. Corvol, and F. Pinet. 2003. Implication of Ref-1 in the repression of renin gene transcription by intracellular calcium. J. Hy-pertens. 21:327-335.
-
(2003)
J. Hy-pertens
, vol.21
, pp. 327-335
-
-
Fuchs, S.1
Philippe, J.2
Corvol, P.3
Pinet, F.4
-
27
-
-
22044451437
-
The role of glial cell line-derived neuro-trophic factor (GDNF) and integrins for invasion and metastasis in human pancreatic cancer cells
-
Funahashi, H., Y. Okada, H. Sawai, H. Takahashi, Y. Matsuo, H. Takeyama, and T. Manabe. 2005. The role of glial cell line-derived neuro-trophic factor (GDNF) and integrins for invasion and metastasis in human pancreatic cancer cells. J. Surg. Oncol. 91:77-83.
-
(2005)
J. Surg. Oncol
, vol.91
, pp. 77-83
-
-
Funahashi, H.1
Okada, Y.2
Sawai, H.3
Takahashi, H.4
Matsuo, Y.5
Takeyama, H.6
Manabe, T.7
-
28
-
-
0043095440
-
Alteration of integrin expression by glial cell line-derived neurotrophic factor (GDNF) in human pancreatic cancer cells
-
Funahashi, H., H. Takeyama, H. Sawai, A, Furuta, M. Sato, Y. Okada, T. Hayakawa, M. Tanaka, and T. Manabe. 2003. Alteration of integrin expression by glial cell line-derived neurotrophic factor (GDNF) in human pancreatic cancer cells. Pancreas 27:190-196.
-
(2003)
Pancreas
, vol.27
, pp. 190-196
-
-
Funahashi, H.1
Takeyama, H.2
Sawai, H.3
Furuta, A.4
Sato, M.5
Okada, Y.6
Hayakawa, T.7
Tanaka, M.8
Manabe, T.9
-
29
-
-
13344277993
-
Functional recovery in Parkinsonian monkeys treated with GDNF
-
Gash, D. M, Z. Zhang, A. Ovadia, W. A. Cass, A. Yi, L. Simmerman, D. Russell, D. Martin, P. A. Lapchak, F. Collins, B. J. Hoffer, and G. A. Gerhardt. 1996. Functional recovery in Parkinsonian monkeys treated with GDNF. Nature 380:252-255.
-
(1996)
Nature
, vol.380
, pp. 252-255
-
-
Gash, D.M.1
Zhang, Z.2
Ovadia, A.3
Cass, W.A.4
Yi, A.5
Simmerman, L.6
Russell, D.7
Martin, D.8
Lapchak, P.A.9
Collins, F.10
Hoffer, B.J.11
Gerhardt, G.A.12
-
30
-
-
0033999274
-
Expression of matrix metalloproteinases and the tissue inhibitors of metalloproteinases and their local invasiveness and metastasis in Chinese human pancreatic cancer
-
Gong, Y. L., G. M. Xu, W. D. Huang, and L. B. Chen. 2000. Expression of matrix metalloproteinases and the tissue inhibitors of metalloproteinases and their local invasiveness and metastasis in Chinese human pancreatic cancer. J. Surg. Oncol. 73:95-99.
-
(2000)
J. Surg. Oncol
, vol.73
, pp. 95-99
-
-
Gong, Y.L.1
Xu, G.M.2
Huang, W.D.3
Chen, L.B.4
-
31
-
-
0029080314
-
Expression and in-situ localization of genes coding for extracellular matrix proteins and extracellular matrix degrading proteases in pancreatic cancer
-
Gress, T. M, F. Muller-Pillasch, M. M. Lerch, H. Friess, M. Buchler, and G. Adler. 1995. Expression and in-situ localization of genes coding for extracellular matrix proteins and extracellular matrix degrading proteases in pancreatic cancer. Int. J. Cancer 62:407-413.
-
(1995)
Int. J. Cancer
, vol.62
, pp. 407-413
-
-
Gress, T.M.1
Muller-Pillasch, F.2
Lerch, M.M.3
Friess, H.4
Buchler, M.5
Adler, G.6
-
32
-
-
0032188756
-
Apurinic endonuclease (Ref-1) is induced in mammalian cells by oxidative stress and involved in clastogenic adaptation
-
Grosch, S., G. Fritz, and B. Kaina. 1998. Apurinic endonuclease (Ref-1) is induced in mammalian cells by oxidative stress and involved in clastogenic adaptation. Cancer Res. 58:4410-4416.
-
(1998)
Cancer Res
, vol.58
, pp. 4410-4416
-
-
Grosch, S.1
Fritz, G.2
Kaina, B.3
-
33
-
-
11144230576
-
Loss of redox factor 1 decreases NF-κB activity and increases susceptibility of endothelial cells to apoptosis
-
Guan, Z., D. Basi, Q. Li, A. Mariash, Y. F. Xia, J. G. Geng, E. Kao, and J. L. Hall. 2005. Loss of redox factor 1 decreases NF-κB activity and increases susceptibility of endothelial cells to apoptosis. Arterioscler. Thromb. Vase. Biol. 25:96-101.
-
(2005)
Arterioscler. Thromb. Vase. Biol
, vol.25
, pp. 96-101
-
-
Guan, Z.1
Basi, D.2
Li, Q.3
Mariash, A.4
Xia, Y.F.5
Geng, J.G.6
Kao, E.7
Hall, J.L.8
-
34
-
-
0035933483
-
Overex-pression of Ref-1 inhibits hypoxia and tumor necrosis factor-induced endothelial cell apoptosis through nuclear factor-κB-independent and -dependent pathways
-
Hall, J. L., X. Wang, A, Van, Y. Zhao, and G. H. Gibbons. 2001. Overex-pression of Ref-1 inhibits hypoxia and tumor necrosis factor-induced endothelial cell apoptosis through nuclear factor-κB-independent and -dependent pathways. Circ. Res. 88:1247-1253.
-
(2001)
Circ. Res
, vol.88
, pp. 1247-1253
-
-
Hall, J.L.1
Wang, X.2
Van, A.3
Zhao, Y.4
Gibbons, G.H.5
-
35
-
-
7844241550
-
Levels of the DNA repair enzyme human apurinic/apyrimidinic endonuclease (APE1, APEX, Ref-1) are associated with the intrinsic radiosensitivity of cervical cancers
-
Herring, C. J., C. M. West, D. P. Wilks, S. E. Davidson, R. D. Hunter, P. Berry, G. Forster, J. MacKinnon, J. A. Rafferty, R. H. Elder, J. H. Hendry, and G. P. Margison. 1998. Levels of the DNA repair enzyme human apurinic/apyrimidinic endonuclease (APE1, APEX, Ref-1) are associated with the intrinsic radiosensitivity of cervical cancers. Br. J. Cancer 78:1128-1133.
-
(1998)
Br. J. Cancer
, vol.78
, pp. 1128-1133
-
-
Herring, C.J.1
West, C.M.2
Wilks, D.P.3
Davidson, S.E.4
Hunter, R.D.5
Berry, P.6
Forster, G.7
MacKinnon, J.8
Rafferty, J.A.9
Elder, R.H.10
Hendry, J.H.11
Margison, G.P.12
-
36
-
-
0030936568
-
AP-1 transcriptional activity is regulated by a direct association between thioredoxin and Ref-1
-
Hirota, K., M. Matsui, S. Iwata, A. Nishiyama, K. Mori, and J. Yodoi. 1997. AP-1 transcriptional activity is regulated by a direct association between thioredoxin and Ref-1. Proc. Natl. Acad. Sci. USA 94:3633-3638.
-
(1997)
Proc. Natl. Acad. Sci. USA
, vol.94
, pp. 3633-3638
-
-
Hirota, K.1
Matsui, M.2
Iwata, S.3
Nishiyama, A.4
Mori, K.5
Yodoi, J.6
-
37
-
-
0035879047
-
Activation of APE/Ref-1 redox activity is mediated by reactive oxygen species and PKC phosphorylation
-
Hsieh, M. M., V. Hegde, M. R. Kelley, and W. A. Deutsch. 2001. Activation of APE/Ref-1 redox activity is mediated by reactive oxygen species and PKC phosphorylation. Nucleic Acids Res. 29:3116-3122.
-
(2001)
Nucleic Acids Res
, vol.29
, pp. 3116-3122
-
-
Hsieh, M.M.1
Hegde, V.2
Kelley, M.R.3
Deutsch, W.A.4
-
38
-
-
0029753008
-
Activation of hypoxia-inducible transcription factor depends primarily upon redox-sensitive stabilization of its alpha subunit
-
Huang, L. E., Z. Arany, D. M. Livingston, and H. F. Bunn. 1996. Activation of hypoxia-inducible transcription factor depends primarily upon redox-sensitive stabilization of its alpha subunit. J. Biol. Chem. 271:32253-32259.
-
(1996)
J. Biol. Chem
, vol.271
, pp. 32253-32259
-
-
Huang, L.E.1
Arany, Z.2
Livingston, D.M.3
Bunn, H.F.4
-
39
-
-
0036140607
-
Expression of glial cell line-derived neurotrophic factor correlates with perineural invasion of bile duct carcinoma
-
Iwahashi, N., T. Nagasaka, G. Tezel, T. Iwashita, N. Asai, Y. Murakumo, K. Kiuchi, K. Sakata, Y. Nimura, and M. Takahashi. 2002. Expression of glial cell line-derived neurotrophic factor correlates with perineural invasion of bile duct carcinoma. Cancer 94:167-174.
-
(2002)
Cancer
, vol.94
, pp. 167-174
-
-
Iwahashi, N.1
Nagasaka, T.2
Tezel, G.3
Iwashita, T.4
Asai, N.5
Murakumo, Y.6
Kiuchi, K.7
Sakata, K.8
Nimura, Y.9
Takahashi, M.10
-
40
-
-
0033923815
-
Requirement for human AP endonuclease 1 for repair of 3'-blocking damage at DNA single-strand breaks induced by reactive oxygen species
-
Izumi, T., T. K. Hazra, I. Boldogh, A. E. Tomkinson, M. S. Park, S. Ikeda, and S. Mitra. 2000. Requirement for human AP endonuclease 1 for repair of 3'-blocking damage at DNA single-strand breaks induced by reactive oxygen species. Carcinogenesis 21:1329-1334.
-
(2000)
Carcinogenesis
, vol.21
, pp. 1329-1334
-
-
Izumi, T.1
Hazra, T.K.2
Boldogh, I.3
Tomkinson, A.E.4
Park, M.S.5
Ikeda, S.6
Mitra, S.7
-
41
-
-
0030478864
-
Negative regulation of the major human AP-endonuclease, a multifunctional protein
-
Izumi, T., W. D. Henner, and S. Mitra. 1996. Negative regulation of the major human AP-endonuclease, a multifunctional protein. Biochemistry 35:14679-14683.
-
(1996)
Biochemistry
, vol.35
, pp. 14679-14683
-
-
Izumi, T.1
Henner, W.D.2
Mitra, S.3
-
42
-
-
15844365303
-
GDNF-induced activation of the ret protein tyrosine kinase is mediated by GDNFR-α, a novel receptor for GDNF
-
Jing, S, D. Wen, Y. Yu, P. L. Hoist, Y. Luo, M. Fang, R. Tamir, L. Antonio, Z. Hu, R. Cupples, J. C. Louis, S. Hu, B. W. Altrock, and G. M. Fox. 1996. GDNF-induced activation of the ret protein tyrosine kinase is mediated by GDNFR-α, a novel receptor for GDNF. Cell 85:1113-1124.
-
(1996)
Cell
, vol.85
, pp. 1113-1124
-
-
Jing, S.1
Wen, D.2
Yu, Y.3
Hoist, P.L.4
Luo, Y.5
Fang, M.6
Tamir, R.7
Antonio, L.8
Hu, Z.9
Cupples, R.10
Louis, J.C.11
Hu, S.12
Altrock, B.W.13
Fox, G.M.14
-
43
-
-
0034905642
-
Elevated and altered expression of the multifunctional DNA base excision repair and redox enzyme Ape1/ref-1 in prostate cancer
-
Kelley, M. R., L. Cheng, R. Foster, R. Tritt, J. Jiang, J. Broshears, and M. Koch. 2001. Elevated and altered expression of the multifunctional DNA base excision repair and redox enzyme Ape1/ref-1 in prostate cancer. Clin. Cancer Res. 7:824-830.
-
(2001)
Clin. Cancer Res
, vol.7
, pp. 824-830
-
-
Kelley, M.R.1
Cheng, L.2
Foster, R.3
Tritt, R.4
Jiang, J.5
Broshears, J.6
Koch, M.7
-
44
-
-
1642499508
-
Localized striatal delivery of GDNF as a treatment for Parkinson disease
-
Kirik, D., B. Georgievska, and A, Bjorklund. 2004. Localized striatal delivery of GDNF as a treatment for Parkinson disease. Nat. Neurosci. 7:105-110.
-
(2004)
Nat. Neurosci
, vol.7
, pp. 105-110
-
-
Kirik, D.1
Georgievska, B.2
Bjorklund, A.3
-
45
-
-
0030916372
-
Evidence of reduced DNA repair in amyotrophic lateral sclerosis brain tissue
-
Kisby, G. E., J. Milne, and C. Sweatt. 1997. Evidence of reduced DNA repair in amyotrophic lateral sclerosis brain tissue. Neuroreport 8:1337-1340.
-
(1997)
Neuroreport
, vol.8
, pp. 1337-1340
-
-
Kisby, G.E.1
Milne, J.2
Sweatt, C.3
-
46
-
-
16944365682
-
A GPI-linked protein that interacts with Ret to form a candidate neurturin receptor
-
Klein, R. D., D. Sherman, W. H. Ho, D. Stone, G. L. Bennett, B. Moffat, R. Vandlen, L. Simmons, Q. Gu, J. A. Hongo, B. Devaux, K. Poulsen, M. Armanini, C. Nozaki, N. Asai, A. Goddard, H. Phillips, C. E. Henderson, M. Takahashi, and A. Rosenthal. 1997. A GPI-linked protein that interacts with Ret to form a candidate neurturin receptor. Nature 387:717-721.
-
(1997)
Nature
, vol.387
, pp. 717-721
-
-
Klein, R.D.1
Sherman, D.2
Ho, W.H.3
Stone, D.4
Bennett, G.L.5
Moffat, B.6
Vandlen, R.7
Simmons, L.8
Gu, Q.9
Hongo, J.A.10
Devaux, B.11
Poulsen, K.12
Armanini, M.13
Nozaki, C.14
Asai, N.15
Goddard, A.16
Phillips, H.17
Henderson, C.E.18
Takahashi, M.19
Rosenthal, A.20
more..
-
47
-
-
0036464533
-
Human AP-endonuclease 1 and hnRNP-L interact with a nCaRE-like repressor element in the AP-endonuclease 1 promoter
-
Kuninger, D. T., T. Izumi, J. Papaconstantinou, and S. Mitra. 2002. Human AP-endonuclease 1 and hnRNP-L interact with a nCaRE-like repressor element in the AP-endonuclease 1 promoter. Nucleic Acids Res. 30:823-829.
-
(2002)
Nucleic Acids Res
, vol.30
, pp. 823-829
-
-
Kuninger, D.T.1
Izumi, T.2
Papaconstantinou, J.3
Mitra, S.4
-
48
-
-
12144287121
-
Transcription factors NF-YA regulate the induction of human OGG1 following DNA-alkylating agent methylmethane sulfonate (MMS) treatment
-
Lee, M. R., S. H. Kim, H. J. Cho, K. Y. Lee, A. R. Moon, H. G. Jeong, J. S. Lee, J. W. Hyun, M. H. Chung, and H. J. You. 2004. Transcription factors NF-YA regulate the induction of human OGG1 following DNA-alkylating agent methylmethane sulfonate (MMS) treatment. J. Biol. Chem. 279: 9857-9866.
-
(2004)
J. Biol. Chem
, vol.279
, pp. 9857-9866
-
-
Lee, M.R.1
Kim, S.H.2
Cho, H.J.3
Lee, K.Y.4
Moon, A.R.5
Jeong, H.G.6
Lee, J.S.7
Hyun, J.W.8
Chung, M.H.9
You, H.J.10
-
49
-
-
0034979216
-
Oxidative cellular damage and the reduction of APE/Ref-1 expression after experimental traumatic brain injury
-
Lewen, A., T. Sugawara, Y. Gasche, M. Fujimura, and P. H. Chan. 2001. Oxidative cellular damage and the reduction of APE/Ref-1 expression after experimental traumatic brain injury. Neurobiol. Dis. 8:380-390.
-
(2001)
Neurobiol. Dis
, vol.8
, pp. 380-390
-
-
Lewen, A.1
Sugawara, T.2
Gasche, Y.3
Fujimura, M.4
Chan, P.H.5
-
50
-
-
0027285510
-
GDNF: A glial cell line-derived neurotrophic factor for midbrain dopami-nergic neurons
-
Lin, L. F., D. H. Doherty, J. D. Lile, S. Bektesh, and F. Collins. 1993. GDNF: a glial cell line-derived neurotrophic factor for midbrain dopami-nergic neurons. Science 260:1130-1132.
-
(1993)
Science
, vol.260
, pp. 1130-1132
-
-
Lin, L.F.1
Doherty, D.H.2
Lile, J.D.3
Bektesh, S.4
Collins, F.5
-
51
-
-
0033932552
-
Expression and alternative splicing of mouse Gfra4 suggest roles in endocrine cell development
-
Lindahl, M., T. Tim musk. J. Rossi, M. Saarma, and M. S. Airaksinen. 2000. Expression and alternative splicing of mouse Gfra4 suggest roles in endocrine cell development. Mol. Cell Neurosci. 15:522-533.
-
(2000)
Mol. Cell Neurosci
, vol.15
, pp. 522-533
-
-
Lindahl, M.1
Tim musk, T.2
Rossi, J.3
Saarma, M.4
Airaksinen, M.S.5
-
52
-
-
0015504248
-
Rate of depurination of native deoxyri-bonucleic acid
-
Lindahl, T., and B. Nyberg. 1972. Rate of depurination of native deoxyri-bonucleic acid. Biochemistry 11:3610-3618.
-
(1972)
Biochemistry
, vol.11
, pp. 3610-3618
-
-
Lindahl, T.1
Nyberg, B.2
-
53
-
-
0023015325
-
Mutagenesis by apurinic/apyrimidinic sites
-
Loeb, L. A., and B. D. Preston. 1986. Mutagenesis by apurinic/apyrimidinic sites. Annu. Rev. Genet. 20:201-230.
-
(1986)
Annu. Rev. Genet
, vol.20
, pp. 201-230
-
-
Loeb, L.A.1
Preston, B.D.2
-
54
-
-
0031720426
-
-
Ludwig, D. L., M. A, Maclnnes, Y. Takiguchi, P. E. Purtymun, M. Henrie, M. Flannery, J. Meneses, R. A. Pedersen, and D. J. Chen. 1998. A murine AP-endonuclease gene-targeted deficiency with post-implantation embryonic progression and ionizing radiation sensitivity. Mutat. Res. 409:17-29.
-
Ludwig, D. L., M. A, Maclnnes, Y. Takiguchi, P. E. Purtymun, M. Henrie, M. Flannery, J. Meneses, R. A. Pedersen, and D. J. Chen. 1998. A murine AP-endonuclease gene-targeted deficiency with post-implantation embryonic progression and ionizing radiation sensitivity. Mutat. Res. 409:17-29.
-
-
-
-
55
-
-
0026715172
-
Thioredoxin regulates the DNA binding activity of NF-κB by reduction of a disulphide bond involving cysteine 62
-
Matthews, J. R., N. Wakasugi, J. L. Virelizier, J. Yodoi, and R. T. Hay. 1992. Thioredoxin regulates the DNA binding activity of NF-κB by reduction of a disulphide bond involving cysteine 62. Nucleic Acids Res. 20:3821-3830.
-
(1992)
Nucleic Acids Res
, vol.20
, pp. 3821-3830
-
-
Matthews, J.R.1
Wakasugi, N.2
Virelizier, J.L.3
Yodoi, J.4
Hay, R.T.5
-
56
-
-
17944401554
-
Regulation of cell fate decision of undifferentiated spermatogonia by GDNF
-
Meng, X., M. Lindahl, M. E. Hyvonen, M. Parvinen, D. G. de Rooij, M. W. Hess, A, Raatikainen-Ahokas, K. Sainio, H. Rauvala, M. Lakso, J. G. Pichel, H. Westphal, M. Saarma, and H. Sariola. 2000. Regulation of cell fate decision of undifferentiated spermatogonia by GDNF. Science 287: 1489-1493.
-
(2000)
Science
, vol.287
, pp. 1489-1493
-
-
Meng, X.1
Lindahl, M.2
Hyvonen, M.E.3
Parvinen, M.4
de Rooij, D.G.5
Hess, M.W.6
Raatikainen-Ahokas, A.7
Sainio, K.8
Rauvala, H.9
Lakso, M.10
Pichel, J.G.11
Westphal, H.12
Saarma, M.13
Sariola, H.14
-
57
-
-
0027963233
-
Two different cellular redox systems regulate the DNA-binding activity of the p50 subunit of NF-κB in vitro
-
Mitomo, K., K. Nakayama, K. Fujimoto, X. Sun, S. Seki, and K. Yamamoto. 1994. Two different cellular redox systems regulate the DNA-binding activity of the p50 subunit of NF-κB in vitro. Gene 145:197-203.
-
(1994)
Gene
, vol.145
, pp. 197-203
-
-
Mitomo, K.1
Nakayama, K.2
Fujimoto, K.3
Sun, X.4
Seki, S.5
Yamamoto, K.6
-
58
-
-
0034719372
-
-
Mol, C. D., T. Izumi, S. Mitra, and J. A, Tainer. 2000. DNA-bound structures and mutants reveal abasic DNA binding by APE1 and DNA repair coordination. Nature 403:451-456.
-
Mol, C. D., T. Izumi, S. Mitra, and J. A, Tainer. 2000. DNA-bound structures and mutants reveal abasic DNA binding by APE1 and DNA repair coordination. Nature 403:451-456.
-
-
-
-
59
-
-
0033961301
-
Alterations in the expression of the DNA repair/redox enzyme APE/Ref-1 in epithelial ovarian cancers
-
Moore, D. H., H. Michael, R. Tritt, S. H. Parsons, and M. R. Kelley. 2000. Alterations in the expression of the DNA repair/redox enzyme APE/Ref-1 in epithelial ovarian cancers. Clin. Cancer Res. 6:602-609.
-
(2000)
Clin. Cancer Res
, vol.6
, pp. 602-609
-
-
Moore, D.H.1
Michael, H.2
Tritt, R.3
Parsons, S.H.4
Kelley, M.R.5
-
60
-
-
15844384629
-
Renal and neuronal abnormalities in mice lacking GDNF
-
Moore, M. W., R. D. Klein, I. Farinas, H. Sauer, M. Armanini, H. Phillips, L. F. Reichardt, A. M. Ryan, K. Carver-Moore, and A. Rosenthal. 1996. Renal and neuronal abnormalities in mice lacking GDNF. Nature 382:76-79.
-
(1996)
Nature
, vol.382
, pp. 76-79
-
-
Moore, M.W.1
Klein, R.D.2
Farinas, I.3
Sauer, H.4
Armanini, M.5
Phillips, H.6
Reichardt, L.F.7
Ryan, A.M.8
Carver-Moore, K.9
Rosenthal, A.10
-
61
-
-
0036177290
-
Histologic features of venous invasion, expression of vascular endothelial growth factor and matrix metalloproteinase-2 and matrix metalloprotein-ase-9, and the relation with liver metastasis in pancreatic cancer
-
Nagakawa, Y., T. Aoki, K. Kasuya, A, Tsuchida, and Y. Koyanagi. 2002. Histologic features of venous invasion, expression of vascular endothelial growth factor and matrix metalloproteinase-2 and matrix metalloprotein-ase-9, and the relation with liver metastasis in pancreatic cancer. Pancreas 24:169-178.
-
(2002)
Pancreas
, vol.24
, pp. 169-178
-
-
Nagakawa, Y.1
Aoki, T.2
Kasuya, K.3
Tsuchida, A.4
Koyanagi, Y.5
-
62
-
-
0029869717
-
Clinical significance of carcinoma invasion of the extrapancreatic nerve plexus in pancreatic cancer
-
Nakao, A., A. Harada, T. Nonami, T. Kaneko, and H. Takagi. 1996. Clinical significance of carcinoma invasion of the extrapancreatic nerve plexus in pancreatic cancer. Pancreas 12:357-361.
-
(1996)
Pancreas
, vol.12
, pp. 357-361
-
-
Nakao, A.1
Harada, A.2
Nonami, T.3
Kaneko, T.4
Takagi, H.5
-
63
-
-
0347367072
-
Spatial redox regulation of a critical cysteine residue of NF-κB in vivo
-
Nishi, T., N. Shimizu, M. Hiramoto, I. Sato, Y. Yamaguchi, M. Hasegawa, S. Aizawa, H. Tanaka, K. Kataoka, H. Watanabe, and H. Handa. 2002. Spatial redox regulation of a critical cysteine residue of NF-κB in vivo. J. Biol. Chem. 277:44548-44556.
-
(2002)
J. Biol. Chem
, vol.277
, pp. 44548-44556
-
-
Nishi, T.1
Shimizu, N.2
Hiramoto, M.3
Sato, I.4
Yamaguchi, Y.5
Hasegawa, M.6
Aizawa, S.7
Tanaka, H.8
Kataoka, K.9
Watanabe, H.10
Handa, H.11
-
64
-
-
0042328053
-
Glial cell-derived neurotrophic factor upregulates the expression and activation of matrix metalloproteinase-9 in human pancreatic cancer
-
Okada, Y., G. Eibl, J. P. Duffy, H. A. Reber, and O. J. Hines. 2003. Glial cell-derived neurotrophic factor upregulates the expression and activation of matrix metalloproteinase-9 in human pancreatic cancer. Surgery 134: 293-299.
-
(2003)
Surgery
, vol.134
, pp. 293-299
-
-
Okada, Y.1
Eibl, G.2
Duffy, J.P.3
Reber, H.A.4
Hines, O.J.5
-
65
-
-
0027985675
-
A redox factor protein, Ref1, is involved in negative gene regulation by extracellular calcium
-
Okazaki, T., U. Chung, T. Nishishita, S. Ebisu, S. Usuda, S. Mishiro, S. Xanthoudakis, T. Igarashi, and E. Ogata. 1994. A redox factor protein, Ref1, is involved in negative gene regulation by extracellular calcium. J. Biol. Chem. 269:27855-27862.
-
(1994)
J. Biol. Chem
, vol.269
, pp. 27855-27862
-
-
Okazaki, T.1
Chung, U.2
Nishishita, T.3
Ebisu, S.4
Usuda, S.5
Mishiro, S.6
Xanthoudakis, S.7
Igarashi, T.8
Ogata, E.9
-
66
-
-
0032567807
-
Mutant AP endonuclease in patients with amyotro-phic lateral sclerosis
-
Olkowski, Z. L. 1998. Mutant AP endonuclease in patients with amyotro-phic lateral sclerosis. Neuroreport 9:239-242.
-
(1998)
Neuroreport
, vol.9
, pp. 239-242
-
-
Olkowski, Z.L.1
-
67
-
-
0028244814
-
Stable expression in rat glioma cells of sense and antisense nucleic acids to a human multifunctional DNA repair enzyme, APEX nuclease
-
Ono, Y., T. Furuta, T. Ohmoto, K. Akiyama, and S. Seki. 1994. Stable expression in rat glioma cells of sense and antisense nucleic acids to a human multifunctional DNA repair enzyme, APEX nuclease. Mutat. Res. 315:55-63.
-
(1994)
Mutat. Res
, vol.315
, pp. 55-63
-
-
Ono, Y.1
Furuta, T.2
Ohmoto, T.3
Akiyama, K.4
Seki, S.5
-
68
-
-
0028823440
-
Relationship between expression of a major apurinic/apyrimidinic endonuclease (APEX nuclease) and susceptibility to genotoxic agents in human glioma cell lines
-
Ono, Y., K. Matsumoto, T. Furuta, T. Ohmoto, K. Akiyama, and S. Seki. 1995. Relationship between expression of a major apurinic/apyrimidinic endonuclease (APEX nuclease) and susceptibility to genotoxic agents in human glioma cell lines. J. Neurooncol. 25:183-192.
-
(1995)
J. Neurooncol
, vol.25
, pp. 183-192
-
-
Ono, Y.1
Matsumoto, K.2
Furuta, T.3
Ohmoto, T.4
Akiyama, K.5
Seki, S.6
-
69
-
-
0038655553
-
Cysteine 64 of Ref-1 is not essential for redox regulation of AP-1 DNA binding
-
Ordway, J. M., D. Eberhart, and T. Curran. 2003. Cysteine 64 of Ref-1 is not essential for redox regulation of AP-1 DNA binding. Mol. Cell. Biol. 23:4257-4266.
-
(2003)
Mol. Cell. Biol
, vol.23
, pp. 4257-4266
-
-
Ordway, J.M.1
Eberhart, D.2
Curran, T.3
-
70
-
-
15844426332
-
Defects in enteric innervation and kidney development in mice lacking GDNF
-
Pichel, J. G., L. Shen, H. Z. Sheng, A. C. Granholm, J. Drago, A. Grinberg, E. J. Lee, S. P. Huang, M. Saarma, B. J. Hoffer, H. Sariola, and H. Westphal. 1996. Defects in enteric innervation and kidney development in mice lacking GDNF. Nature 382:73-76.
-
(1996)
Nature
, vol.382
, pp. 73-76
-
-
Pichel, J.G.1
Shen, L.2
Sheng, H.Z.3
Granholm, A.C.4
Drago, J.5
Grinberg, A.6
Lee, E.J.7
Huang, S.P.8
Saarma, M.9
Hoffer, B.J.10
Sariola, H.11
Westphal, H.12
-
71
-
-
0345352666
-
GDNF promotes tubulogenesis of GFRαl-expressing MDCK cells by Src-mediated phosphorylation of Met receptor tyrosine kinase
-
Popsueva, A., D. Poteryaev, E. Arighi, X. Meng, A. Angers-Loustau, D. Kaplan, M. Saarma, and H. Sariola. 2003. GDNF promotes tubulogenesis of GFRαl-expressing MDCK cells by Src-mediated phosphorylation of Met receptor tyrosine kinase. J. Cell Biol. 161:119-129.
-
(2003)
J. Cell Biol
, vol.161
, pp. 119-129
-
-
Popsueva, A.1
Poteryaev, D.2
Arighi, E.3
Meng, X.4
Angers-Loustau, A.5
Kaplan, D.6
Saarma, M.7
Sariola, H.8
-
72
-
-
0033407604
-
GDNF triggers a novel ret-independent Src kinase family-coupled signaling via a GPI-linked GDNF receptor alpha1
-
Poteryaev, D., A. Titievsky, Y. F. Sun, J. Thomas-Crusells, M. Lindahl, M. Billaud, U. Arumae, and M. Saarma. 1999. GDNF triggers a novel ret-independent Src kinase family-coupled signaling via a GPI-linked GDNF receptor alpha1. FEBS Lett. 463:63-66.
-
(1999)
FEBS Lett
, vol.463
, pp. 63-66
-
-
Poteryaev, D.1
Titievsky, A.2
Sun, Y.F.3
Thomas-Crusells, J.4
Lindahl, M.5
Billaud, M.6
Arumae, U.7
Saarma, M.8
-
73
-
-
0032574770
-
Activation of apurinic/apyrimidinic endonuclease in human cells by reactive oxygen species and its correlation with their adaptive response to genotoxicity of free radicals
-
Ramana, C. V., I. Boldogh, T. Izumi, and S. Mitra. 1998. Activation of apurinic/apyrimidinic endonuclease in human cells by reactive oxygen species and its correlation with their adaptive response to genotoxicity of free radicals. Proc. Natl. Acad. Sci. USA 95:5061-5066.
-
(1998)
Proc. Natl. Acad. Sci. USA
, vol.95
, pp. 5061-5066
-
-
Ramana, C.V.1
Boldogh, I.2
Izumi, T.3
Mitra, S.4
-
74
-
-
0035266131
-
Altered expression of Ape1/ref-1 in germ cell tumors and overexpression in NT2 cells confers resistance to bleomycin and radiation
-
Robertson, K. A., H. A. Bullock, Y. Xu, R. Tritt, E. Zimmerman, T. M. Ulbright, R. S. Foster, L. H. Einhorn, and M. R. Kelley. 2001. Altered expression of Ape1/ref-1 in germ cell tumors and overexpression in NT2 cells confers resistance to bleomycin and radiation. Cancer Res. 61:2220-2225.
-
(2001)
Cancer Res
, vol.61
, pp. 2220-2225
-
-
Robertson, K.A.1
Bullock, H.A.2
Xu, Y.3
Tritt, R.4
Zimmerman, E.5
Ulbright, T.M.6
Foster, R.S.7
Einhorn, L.H.8
Kelley, M.R.9
-
75
-
-
0033563301
-
Other neurotrophic factors: Glial cell line-derived neurotrophic factor (GDNF)
-
Saarma, M., and H. Sariola. 1999. Other neurotrophic factors: glial cell line-derived neurotrophic factor (GDNF). Microsc. Res. Tech. 45:292-302.
-
(1999)
Microsc. Res. Tech
, vol.45
, pp. 292-302
-
-
Saarma, M.1
Sariola, H.2
-
76
-
-
0037328721
-
Oxidative damage and reduction of redox factor-1 expression after transient spinal cord ischemia in rabbits
-
Sakurai, M., T. Nagata, K. Abe, T. Horinouchi, Y. Itoyama, and K. Taba-yashi. 2003. Oxidative damage and reduction of redox factor-1 expression after transient spinal cord ischemia in rabbits. J. Vase. Surg. 37:446-452.
-
(2003)
J. Vase. Surg
, vol.37
, pp. 446-452
-
-
Sakurai, M.1
Nagata, T.2
Abe, K.3
Horinouchi, T.4
Itoyama, Y.5
Taba-yashi, K.6
-
77
-
-
0029901727
-
-
Sanchez, M. P., I. Silos-Santiago, J. Frisen, B. He, S. A, Lira, and M. Barbacid. 1996. Renal agenesis and the absence of enteric neurons in mice lacking GDNF. Nature 382:70-73.
-
Sanchez, M. P., I. Silos-Santiago, J. Frisen, B. He, S. A, Lira, and M. Barbacid. 1996. Renal agenesis and the absence of enteric neurons in mice lacking GDNF. Nature 382:70-73.
-
-
-
-
78
-
-
0142106351
-
Novel functions and signalling pathways for GDNF
-
Sariola, H., and M. Saarma. 2003. Novel functions and signalling pathways for GDNF. J. Cell Sci. 116:3855-3862.
-
(2003)
J. Cell Sci
, vol.116
, pp. 3855-3862
-
-
Sariola, H.1
Saarma, M.2
-
79
-
-
29244490072
-
The G691S RET polymorphism increases glial cell line-derived neurotrophic factor-induced pancreatic cancer cell invasion by amplifying mitogen-activated protein kinase signaling
-
Sawai, H., Y. Okada, K. Kazanjian, J. Kim, S. Hasan, O. J. Hines, H. A. Reber, D. S. Hoon, and G. Eibl. 2005. The G691S RET polymorphism increases glial cell line-derived neurotrophic factor-induced pancreatic cancer cell invasion by amplifying mitogen-activated protein kinase signaling. Cancer Res. 65:11536-11544.
-
(2005)
Cancer Res
, vol.65
, pp. 11536-11544
-
-
Sawai, H.1
Okada, Y.2
Kazanjian, K.3
Kim, J.4
Hasan, S.5
Hines, O.J.6
Reber, H.A.7
Hoon, D.S.8
Eibl, G.9
-
80
-
-
0033877274
-
High-performance affinity beads for identifying drug receptors
-
Shimizu, N., K. Sugimoto, J. Tang, T. Nishi, I. Sato, M. Hiramoto, S. Aizawa, M. Hatakeyama, R. Ohba, H. Hatori, T. Yoshikawa, F. Suzuki, A. Oomori, H. Tanaka, H. Kawaguchi, H. Watanabe, and H. Handa. 2000. High-performance affinity beads for identifying drug receptors. Nat. Bio-technol. 18:877-881.
-
(2000)
Nat. Bio-technol
, vol.18
, pp. 877-881
-
-
Shimizu, N.1
Sugimoto, K.2
Tang, J.3
Nishi, T.4
Sato, I.5
Hiramoto, M.6
Aizawa, S.7
Hatakeyama, M.8
Ohba, R.9
Hatori, H.10
Yoshikawa, T.11
Suzuki, F.12
Oomori, A.13
Tanaka, H.14
Kawaguchi, H.15
Watanabe, H.16
Handa, H.17
-
81
-
-
0035188727
-
How matrix metalloproteinases regulate cell behavior
-
Sternlicht, M. D., and Z. Werb. 2001. How matrix metalloproteinases regulate cell behavior. Annu. Rev. Cell Dev. Biol. 17:463-516.
-
(2001)
Annu. Rev. Cell Dev. Biol
, vol.17
, pp. 463-516
-
-
Sternlicht, M.D.1
Werb, Z.2
-
82
-
-
3042774318
-
Glial cell line-derived neurotrophic factor enhances nuclear factor-κB activity and invasive potential in human pancreatic cancer cells
-
Takahashi, H., H. Funahashi, H. Sawai, M. Sakamoto, Y. Matsuo, M. Yamamoto, Y. Okada, T. Hayakawa, and T. Manabe. 2004. Glial cell line-derived neurotrophic factor enhances nuclear factor-κB activity and invasive potential in human pancreatic cancer cells. Pancreas 29:22-27.
-
(2004)
Pancreas
, vol.29
, pp. 22-27
-
-
Takahashi, H.1
Funahashi, H.2
Sawai, H.3
Sakamoto, M.4
Matsuo, Y.5
Yamamoto, M.6
Okada, Y.7
Hayakawa, T.8
Manabe, T.9
-
83
-
-
0032563635
-
Immunohistochemical localization of redox factor-1 (Ref-1) in Alzheimer's hippocampus
-
Tan, Z., N. Sun, and S. S. Schreiber. 1998. Immunohistochemical localization of redox factor-1 (Ref-1) in Alzheimer's hippocampus. Neuroreport 9:2749-2752.
-
(1998)
Neuroreport
, vol.9
, pp. 2749-2752
-
-
Tan, Z.1
Sun, N.2
Schreiber, S.S.3
-
84
-
-
0034994827
-
Histology-specific expression of a DNA repair protein in pediatric rhabdomyosarcomas
-
Thomson, B., R. Tritt, M. Davis, and M. R. Kelley. 2001. Histology-specific expression of a DNA repair protein in pediatric rhabdomyosarcomas. J. Pediatr. Hematol. Oncol. 23:234-239.
-
(2001)
J. Pediatr. Hematol. Oncol
, vol.23
, pp. 234-239
-
-
Thomson, B.1
Tritt, R.2
Davis, M.3
Kelley, M.R.4
-
85
-
-
0028834063
-
Protection and repair of the nigrostriatal dopaminergic system by GDNF in vivo
-
Tomac, A., E. Lindqvist, L. F. Lin, S. O. Ogren, D. Young, B. J. Hoffer, and L. Olson. 1995. Protection and repair of the nigrostriatal dopaminergic system by GDNF in vivo. Nature 373:335-339.
-
(1995)
Nature
, vol.373
, pp. 335-339
-
-
Tomac, A.1
Lindqvist, E.2
Lin, L.F.3
Ogren, S.O.4
Young, D.5
Hoffer, B.J.6
Olson, L.7
-
86
-
-
15844418441
-
Characterization of a multicomponent receptor for GDNF
-
Treanor, J. J., L. Goodman, F. de Sauvage, D. M. Stone, K. T. Poulsen, C. D. Beck, C. Gray, M. P. Armanini, R. A. Pollock, F. Hefti, H. S. Phillips, A. Goddard, M. W. Moore, A. Buj-Bello, A. M. Davies, N. Asai, M. Takahashi, R. Vandlen, C. E. Henderson, and A. Rosenthal. 1996. Characterization of a multicomponent receptor for GDNF. Nature 382:80-83.
-
(1996)
Nature
, vol.382
, pp. 80-83
-
-
Treanor, J.J.1
Goodman, L.2
de Sauvage, F.3
Stone, D.M.4
Poulsen, K.T.5
Beck, C.D.6
Gray, C.7
Armanini, M.P.8
Pollock, R.A.9
Hefti, F.10
Phillips, H.S.11
Goddard, A.12
Moore, M.W.13
Buj-Bello, A.14
Davies, A.M.15
Asai, N.16
Takahashi, M.17
Vandlen, R.18
Henderson, C.E.19
Rosenthal, A.20
more..
-
87
-
-
0030915959
-
Complementary and overlapping expression of glial cell line-derived neurotrophic factor (GDNF), c-ret proto-oncogene, and GDNF receptor-alpha indicates multiple mechanisms of trophic actions in the adult rat CNS
-
Trupp, M., N. Belluardo, H. Funakoshi, and C. F. Ibanez. 1997. Complementary and overlapping expression of glial cell line-derived neurotrophic factor (GDNF), c-ret proto-oncogene, and GDNF receptor-alpha indicates multiple mechanisms of trophic actions in the adult rat CNS. J. Neurosci. 17:3554-3567.
-
(1997)
J. Neurosci
, vol.17
, pp. 3554-3567
-
-
Trupp, M.1
Belluardo, N.2
Funakoshi, H.3
Ibanez, C.F.4
-
88
-
-
0033597817
-
Ret-dependent and -independent mechanisms of glial cell line-derived neurotrophic factor signaling in neuronal cells
-
Trupp, M., R. Scott, S. R. Whittemore, and C. F. Ibanez. 1999. Ret-dependent and -independent mechanisms of glial cell line-derived neurotrophic factor signaling in neuronal cells. J. Biol. Chem. 274:20885-20894.
-
(1999)
J. Biol. Chem
, vol.274
, pp. 20885-20894
-
-
Trupp, M.1
Scott, R.2
Whittemore, S.R.3
Ibanez, C.F.4
-
89
-
-
12344291209
-
The multifunctional DNA repair/redox enzyme Ape1/Ref-1 promotes survival of neurons after oxidative stress
-
Vasko, M. R., C. Guo, and M. R. Kelley. 2005. The multifunctional DNA repair/redox enzyme Ape1/Ref-1 promotes survival of neurons after oxidative stress. DNA Repair 4:367-379.
-
(2005)
DNA Repair
, vol.4
, pp. 367-379
-
-
Vasko, M.R.1
Guo, C.2
Kelley, M.R.3
-
90
-
-
3442876128
-
Activation of phosphatidylinositol 3-kinase and extracellular signal-regulated kinase is required for glial cell line-derived neurotrophic factor-induced migration and invasion of pancreatic carcinoma cells
-
Veit, C., F. Genze, A. Menke, S. Hoeffert, T. M. Gress, P. Gierschik, and K. Giehl. 2004. Activation of phosphatidylinositol 3-kinase and extracellular signal-regulated kinase is required for glial cell line-derived neurotrophic factor-induced migration and invasion of pancreatic carcinoma cells. Cancer Res. 64:5291-5300.
-
(2004)
Cancer Res
, vol.64
, pp. 5291-5300
-
-
Veit, C.1
Genze, F.2
Menke, A.3
Hoeffert, S.4
Gress, T.M.5
Gierschik, P.6
Giehl, K.7
-
91
-
-
0028596574
-
A role for the human DNA repair enzyme HAP1 in cellular protection against DNA-damaging agents and hypoxic stress
-
Walker, L. J., R. B. Craig, A. L. Harris, and I. D. Hickson. 1994. A role for the human DNA repair enzyme HAP1 in cellular protection against DNA-damaging agents and hypoxic stress. Nucleic Acids Res. 22:4884-4889.
-
(1994)
Nucleic Acids Res
, vol.22
, pp. 4884-4889
-
-
Walker, L.J.1
Craig, R.B.2
Harris, A.L.3
Hickson, I.D.4
-
92
-
-
0027324056
-
Identification of residues in the human DNA repair enzyme HAP1 (Ref-1) that are essential for redox regulation of Jun DNA binding
-
Walker, L. J., C. N. Robson, E. Black, D. Gillespie, and I. D. Hickson. 1993. Identification of residues in the human DNA repair enzyme HAP1 (Ref-1) that are essential for redox regulation of Jun DNA binding. Mol. Cell. Biol. 13:5370-5376.
-
(1993)
Mol. Cell. Biol
, vol.13
, pp. 5370-5376
-
-
Walker, L.J.1
Robson, C.N.2
Black, E.3
Gillespie, D.4
Hickson, I.D.5
-
93
-
-
0031036811
-
Loss of Ref-1 protein expression precedes DNA fragmentation in apoptotic neurons
-
Walton, M., P. Lawlor, E. Sirimanne, C. Williams, P. Gluckman, and M. Dragunow. 1997. Loss of Ref-1 protein expression precedes DNA fragmentation in apoptotic neurons. Brain Res. Mol. Brain Res. 44:167-170.
-
(1997)
Brain Res. Mol. Brain Res
, vol.44
, pp. 167-170
-
-
Walton, M.1
Lawlor, P.2
Sirimanne, E.3
Williams, C.4
Gluckman, P.5
Dragunow, M.6
-
94
-
-
4444327784
-
Human apurinic endonuclease 1 (APE1) expression and prognostic significance in osteosarcoma: Enhanced sensitivity of osteosarcoma to DNA-damaging agents using silencing RNA APE1 expression inhibition
-
Wang, D., M. Luo, and M. R. Kelley. 2004. Human apurinic endonuclease 1 (APE1) expression and prognostic significance in osteosarcoma: enhanced sensitivity of osteosarcoma to DNA-damaging agents using silencing RNA APE1 expression inhibition. Mol. Cancer Ther. 3:679-686.
-
(2004)
Mol. Cancer Ther
, vol.3
, pp. 679-686
-
-
Wang, D.1
Luo, M.2
Kelley, M.R.3
-
95
-
-
0030004546
-
Differential expression of the apurinic/apyrimidinic endonuclease (APE/ref-1) multifunctional DNA base excision repair gene during fetal development and in adult rat brain and testis
-
Wilson, T. M, S. A. Rivkees, W. A. Deutsch, and M. R. Kelley. 1996. Differential expression of the apurinic/apyrimidinic endonuclease (APE/ref-1) multifunctional DNA base excision repair gene during fetal development and in adult rat brain and testis. Mutat. Res. 362:237-248.
-
(1996)
Mutat. Res
, vol.362
, pp. 237-248
-
-
Wilson, T.M.1
Rivkees, S.A.2
Deutsch, W.A.3
Kelley, M.R.4
-
96
-
-
0026583944
-
Identification and characterization of Ref-1, a nuclear protein that facilitates AP-1 DNA-binding activity
-
Xanthoudakis, S., and T. Curran. 1992. Identification and characterization of Ref-1, a nuclear protein that facilitates AP-1 DNA-binding activity. EMBO J. 11:653-665.
-
(1992)
EMBO J
, vol.11
, pp. 653-665
-
-
Xanthoudakis, S.1
Curran, T.2
-
97
-
-
0026714672
-
Redox activation of Fos-Jun DNA binding activity is mediated by a DNA repair enzyme
-
Xanthoudakis, S., G. Miao, F. Wang, Y. C. Pan, and T. Curran. 1992. Redox activation of Fos-Jun DNA binding activity is mediated by a DNA repair enzyme. EMBO J. 11:3323-3335.
-
(1992)
EMBO J
, vol.11
, pp. 3323-3335
-
-
Xanthoudakis, S.1
Miao, G.2
Wang, F.3
Pan, Y.C.4
Curran, T.5
-
98
-
-
0031439376
-
The apurinic/apyrimidinic endonuclease (APE/ref-1) DNA repair enzyme is elevated in premalignant and malignant cervical cancer
-
Xu, Y., D. H. Moore, J. Broshears, L. Liu, T. M. Wilson, and M. R. Kelley. 1997. The apurinic/apyrimidinic endonuclease (APE/ref-1) DNA repair enzyme is elevated in premalignant and malignant cervical cancer. Anti-cancer Res. 17:3713-3719.
-
(1997)
Anti-cancer Res
, vol.17
, pp. 3713-3719
-
-
Xu, Y.1
Moore, D.H.2
Broshears, J.3
Liu, L.4
Wilson, T.M.5
Kelley, M.R.6
-
99
-
-
30344434348
-
-
Yang, S., K. Irani, S. E. Heffron, F. Jurnak, and F. L. Meyskens, Jr. 2005. Alterations in the expression of the apurinic/apyrimidinic endonuclease-1/redox factor-1 (APE/Ref-1) in human melanoma and identification of the therapeutic potential of resveratrol as an APE/Ref-1 inhibitor. Mol. Cancer Ther. 4:1923-1935.
-
Yang, S., K. Irani, S. E. Heffron, F. Jurnak, and F. L. Meyskens, Jr. 2005. Alterations in the expression of the apurinic/apyrimidinic endonuclease-1/redox factor-1 (APE/Ref-1) in human melanoma and identification of the therapeutic potential of resveratrol as an APE/Ref-1 inhibitor. Mol. Cancer Ther. 4:1923-1935.
-
-
-
-
100
-
-
36148930625
-
-
Yang, S., B. J. Misner, R. J. Chiu, and F. L. Meyskens, Jr. 2007. Redox effector factor-1, combined with reactive oxygen species, plays an important role in the transformation of JB6 cells. Carcinogenesis 28:2382-2390.
-
Yang, S., B. J. Misner, R. J. Chiu, and F. L. Meyskens, Jr. 2007. Redox effector factor-1, combined with reactive oxygen species, plays an important role in the transformation of JB6 cells. Carcinogenesis 28:2382-2390.
-
-
-
-
101
-
-
0035371329
-
Invasiveness and MMP expression in pancreatic carcinoma
-
Yang, X., E. D. Staren, J. M. Howard, T. Iwamura, J. E. Bartsch, and H. E. Appert. 2001. Invasiveness and MMP expression in pancreatic carcinoma. J. Surg. Res. 98:33-39.
-
(2001)
J. Surg. Res
, vol.98
, pp. 33-39
-
-
Yang, X.1
Staren, E.D.2
Howard, J.M.3
Iwamura, T.4
Bartsch, J.E.5
Appert, H.E.6
-
102
-
-
0036661219
-
-
Yeo, T. P., R. H. Hruban, S. D. Leach, R. E. Wilentz, T. A Sohn, S. E. Kern, C. A. Iacobuzio-Donahue, A. Maitra, M. Goggins, M. I. Canto, R. A. Abrams, D. Laheru, E. M. Jaffee, M. Hidalgo, and C. J. Yeo. 2002. Pancreatic cancer. Curr. Probl. Cancer 26:176-275.
-
Yeo, T. P., R. H. Hruban, S. D. Leach, R. E. Wilentz, T. A Sohn, S. E. Kern, C. A. Iacobuzio-Donahue, A. Maitra, M. Goggins, M. I. Canto, R. A. Abrams, D. Laheru, E. M. Jaffee, M. Hidalgo, and C. J. Yeo. 2002. Pancreatic cancer. Curr. Probl. Cancer 26:176-275.
-
-
-
-
103
-
-
13944266823
-
Bcl-2 expression suppresses mismatch repair activity through inhibition of E2F transcrip-tional activity
-
Youn, C. K., H. J. Cho, S. H. Kim, H. B. Kim, M. H. Kim, I. Y. Chang, J. S. Lee, M. H. Chung, K. S. Hahm, and H. J. You. 2005. Bcl-2 expression suppresses mismatch repair activity through inhibition of E2F transcrip-tional activity. Nat. Cell Biol. 7:137-147.
-
(2005)
Nat. Cell Biol
, vol.7
, pp. 137-147
-
-
Youn, C.K.1
Cho, H.J.2
Kim, S.H.3
Kim, H.B.4
Kim, M.H.5
Chang, I.Y.6
Lee, J.S.7
Chung, M.H.8
Hahm, K.S.9
You, H.J.10
-
104
-
-
6944236323
-
Ref-1/Ape is critical for formation of the hypoxia-inducible transcriptional complex on the hypoxic response element of the rat pulmonary artery endothelial cell VEGF gene
-
Ziel, K. A., C. C. Campbell, G. L. Wilson, and M. N. Gillespie. 2004. Ref-1/Ape is critical for formation of the hypoxia-inducible transcriptional complex on the hypoxic response element of the rat pulmonary artery endothelial cell VEGF gene. FASEB J. 18:986-988.
-
(2004)
FASEB J
, vol.18
, pp. 986-988
-
-
Ziel, K.A.1
Campbell, C.C.2
Wilson, G.L.3
Gillespie, M.N.4
-
105
-
-
51049091691
-
Small-molecule inhibitor of the AP endonuclease 1/REF-l E3330 inhibits pancreatic cancer cell growth and migration
-
Zou, G. M., and A. Maitra. 2008. Small-molecule inhibitor of the AP endonuclease 1/REF-l E3330 inhibits pancreatic cancer cell growth and migration. Mol. Cancer Ther. 7:2012-2021.
-
(2008)
Mol. Cancer Ther
, vol.7
, pp. 2012-2021
-
-
Zou, G.M.1
Maitra, A.2
|