메뉴 건너뛰기




Volumn 29, Issue 8, 2009, Pages 2264-2277

Ape1/Ref-1 induces glial cell-derived neurotropic factor (GDNF) responsiveness by upregulating GDNF receptor α1 expression

Author keywords

[No Author keywords available]

Indexed keywords

AMYLOID BETA PROTEIN; GLIAL CELL LINE DERIVED NEUROTROPHIC FACTOR; GLIAL CELL LINE DERIVED NEUROTROPHIC FACTOR RECEPTOR; GLIAL CELL LINE DERIVED NEUROTROPHIC FACTOR RECEPTOR ALPHA1; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; PROTEIN P50; REDOX EFFECTOR FACTOR 1; UNCLASSIFIED DRUG;

EID: 64649090347     PISSN: 02707306     EISSN: None     Source Type: Journal    
DOI: 10.1128/MCB.01484-08     Document Type: Article
Times cited : (30)

References (105)
  • 1
    • 0025077481 scopus 로고
    • Redox regulation of fos and jun DNA-binding activity in vitro
    • Abate, C., L. Patel, F. J. Rauscher III, and T. Curran. 1990. Redox regulation of fos and jun DNA-binding activity in vitro. Science 249:1157-1161.
    • (1990) Science , vol.249 , pp. 1157-1161
    • Abate, C.1    Patel, L.2    Rauscher III, F.J.3    Curran, T.4
  • 2
    • 0036581222 scopus 로고    scopus 로고
    • The GDNF family: Signalling, biological functions and therapeutic value
    • Airaksinen, M. S., and M. Saarma. 2002. The GDNF family: signalling, biological functions and therapeutic value. Nat. Rev. Neurosci. 3:383-394.
    • (2002) Nat. Rev. Neurosci , vol.3 , pp. 383-394
    • Airaksinen, M.S.1    Saarma, M.2
  • 3
    • 0033023140 scopus 로고    scopus 로고
    • GDNF family neu-rotrophic factor signaling: Four masters, one servant?
    • Airaksinen, M. S., A. Titievsky, and M. Saarma. 1999. GDNF family neu-rotrophic factor signaling: four masters, one servant? Mol. Cell Neurosci. 13:313-325.
    • (1999) Mol. Cell Neurosci , vol.13 , pp. 313-325
    • Airaksinen, M.S.1    Titievsky, A.2    Saarma, M.3
  • 4
    • 48349107170 scopus 로고    scopus 로고
    • A new APE1/Ref-1-dependent pathway leading to reduction of NF-κB and AP-1, and activation of their DNA-binding activity
    • Ando, K., S. Hirao, Y. Kabe, Y. Ogura, I. Sato, Y. Yamaguchi, T. Wada, and H. Handa. 2008. A new APE1/Ref-1-dependent pathway leading to reduction of NF-κB and AP-1, and activation of their DNA-binding activity. Nucleic Acids Res. 36:4327-4336.
    • (2008) Nucleic Acids Res , vol.36 , pp. 4327-4336
    • Ando, K.1    Hirao, S.2    Kabe, Y.3    Ogura, Y.4    Sato, I.5    Yamaguchi, Y.6    Wada, T.7    Handa, H.8
  • 5
    • 0032408664 scopus 로고    scopus 로고
    • Baloh, R. H., M. G. Tansey, P. A, Lampe, T. J. Fahrner, H. Enomoto, K. S. Simburger, M. L. Leitner, T. Araki, E. M. Johnson, Jr., and J. Milbrandt. 1998. Artemin, a novel member of the GDNF ligand family, supports peripheral and central neurons and signals through the GFRα3-RET receptor complex. Neuron 21:1291-1302.
    • Baloh, R. H., M. G. Tansey, P. A, Lampe, T. J. Fahrner, H. Enomoto, K. S. Simburger, M. L. Leitner, T. Araki, E. M. Johnson, Jr., and J. Milbrandt. 1998. Artemin, a novel member of the GDNF ligand family, supports peripheral and central neurons and signals through the GFRα3-RET receptor complex. Neuron 21:1291-1302.
  • 6
    • 0347504848 scopus 로고    scopus 로고
    • Role of acetylated human AP-endonuclease (APE1/Ref-1) in regulation of the parathyroid hormone gene
    • Bhakat, K. K., T. Izumi, S. H. Yang, T. K. Hazra, and S. Mitra. 2003. Role of acetylated human AP-endonuclease (APE1/Ref-1) in regulation of the parathyroid hormone gene. EMBO J. 22:6299-6309.
    • (2003) EMBO J , vol.22 , pp. 6299-6309
    • Bhakat, K.K.1    Izumi, T.2    Yang, S.H.3    Hazra, T.K.4    Mitra, S.5
  • 7
    • 0035176178 scopus 로고    scopus 로고
    • Apurinic/apyrimidinic endonuclease activity is elevated in human adult gliomas
    • Bobola, M. S., A. Blank, M. S. Berger, B. A. Stevens, and J. R. Silber. 2001. Apurinic/apyrimidinic endonuclease activity is elevated in human adult gliomas. Clin. Cancer Res. 7:3510-3518.
    • (2001) Clin. Cancer Res , vol.7 , pp. 3510-3518
    • Bobola, M.S.1    Blank, A.2    Berger, M.S.3    Stevens, B.A.4    Silber, J.R.5
  • 8
    • 0028359164 scopus 로고
    • Interaction of pancreatic ductal carcinoma with nerves leads to nerve damage
    • Bockman, D. E., M. Buchler, and H. G. Beger. 1994. Interaction of pancreatic ductal carcinoma with nerves leads to nerve damage. Gastroenter-ology 107:219-230.
    • (1994) Gastroenter-ology , vol.107 , pp. 219-230
    • Bockman, D.E.1    Buchler, M.2    Beger, H.G.3
  • 10
    • 0033986948 scopus 로고    scopus 로고
    • Redox-regulated recruitment of the transcriptional coac-tivators CREB-binding protein and SRC-1 to hypoxia-inducible factor 1al-pha
    • Carrero, P., K. Okamoto, P. Coumailleau, S. O'Brien, H. Tanaka, and L. Poellinger. 2000. Redox-regulated recruitment of the transcriptional coac-tivators CREB-binding protein and SRC-1 to hypoxia-inducible factor 1al-pha. Mol. Cell. Biol. 20:402-415.
    • (2000) Mol. Cell. Biol , vol.20 , pp. 402-415
    • Carrero, P.1    Okamoto, K.2    Coumailleau, P.3    O'Brien, S.4    Tanaka, H.5    Poellinger, L.6
  • 11
    • 57349170258 scopus 로고    scopus 로고
    • Regulatory role of human AP-endonuclease (APE1/Ref-1) in YB-1-mediated activation of the multi-drug resistance gene MDR1
    • Chattopadhyay, R., S. Das, A. K. Maiti, I. Boldogh, J. Xie, T. K. Hazra, K. Kohno, S. Mitra, and K. K. Bhakat. 2008. Regulatory role of human AP-endonuclease (APE1/Ref-1) in YB-1-mediated activation of the multi-drug resistance gene MDR1. Mol. Cell. Biol. 28:7066-7080.
    • (2008) Mol. Cell. Biol , vol.28 , pp. 7066-7080
    • Chattopadhyay, R.1    Das, S.2    Maiti, A.K.3    Boldogh, I.4    Xie, J.5    Hazra, T.K.6    Kohno, K.7    Mitra, S.8    Bhakat, K.K.9
  • 12
    • 0026004662 scopus 로고
    • Two distinct human DNA diesterases that hydrolyze 3'-blocking deoxyribose fragments from oxidized DNA
    • Chen, D. S., T. Herman, and B. Demple. 1991. Two distinct human DNA diesterases that hydrolyze 3'-blocking deoxyribose fragments from oxidized DNA. Nucleic Acids Res. 19:5907-5914.
    • (1991) Nucleic Acids Res , vol.19 , pp. 5907-5914
    • Chen, D.S.1    Herman, T.2    Demple, B.3
  • 13
    • 0034027636 scopus 로고    scopus 로고
    • Evidence that the bifunctional redox factor/AP endonuclease Ref-1 is an antiapop-totic protein associated with differentiation in the developing retina
    • Chiarini, L. B., F. G. Freitas, H. Petrs-Silva, and R. Linden. 2000. Evidence that the bifunctional redox factor/AP endonuclease Ref-1 is an antiapop-totic protein associated with differentiation in the developing retina. Cell Death Differ. 7:272-281.
    • (2000) Cell Death Differ , vol.7 , pp. 272-281
    • Chiarini, L.B.1    Freitas, F.G.2    Petrs-Silva, H.3    Linden, R.4
  • 15
    • 0037127194 scopus 로고    scopus 로고
    • Coordinated activation of autophosphorylation sites in the RET receptor tyrosine kinase: Importance of tyrosine 1062 for GDNF mediated neuronal differentiation and survival
    • Coulpier, M., J. Anders, and C. F. Ibanez. 2002. Coordinated activation of autophosphorylation sites in the RET receptor tyrosine kinase: importance of tyrosine 1062 for GDNF mediated neuronal differentiation and survival. J. Biol. Chem. 277:1991-1999.
    • (2002) J. Biol. Chem , vol.277 , pp. 1991-1999
    • Coulpier, M.1    Anders, J.2    Ibanez, C.F.3
  • 16
    • 0028342951 scopus 로고
    • Repair of oxidative damage to DNA: Enzymology and biology
    • Demple, B., and L. Harrison. 1994. Repair of oxidative damage to DNA: enzymology and biology. Annu. Rev. Biochem. 63:915-948.
    • (1994) Annu. Rev. Biochem , vol.63 , pp. 915-948
    • Demple, B.1    Harrison, L.2
  • 18
    • 0033118983 scopus 로고    scopus 로고
    • Molecular mechanisms of transcription activation by HLF and HIF1α in response to hypoxia: Their stabilization and redox signal-induced interaction with CBP/p300
    • Ema, M, K. Hirota, J. Mimura, H. Abe, J. Yodoi, K. Sogawa, L. Poellinger, and Y. Fujii-Kuriyama. 1999. Molecular mechanisms of transcription activation by HLF and HIF1α in response to hypoxia: their stabilization and redox signal-induced interaction with CBP/p300. EMBO J. 18:1905-1914.
    • (1999) EMBO J , vol.18 , pp. 1905-1914
    • Ema, M.1    Hirota, K.2    Mimura, J.3    Abe, H.4    Yodoi, J.5    Sogawa, K.6    Poellinger, L.7    Fujii-Kuriyama, Y.8
  • 19
    • 0032504961 scopus 로고    scopus 로고
    • Enokido, Y., F. de Sauvage, J. A, Hongo, N. Ninkina, A, Rosenthal, V. L. Buchman, and A. M. Davies. 1998. GFRa-4 and the tyrosine kinase Ret form a functional receptor complex for persephin. Curr. Biol. 8:1019-1022.
    • Enokido, Y., F. de Sauvage, J. A, Hongo, N. Ninkina, A, Rosenthal, V. L. Buchman, and A. M. Davies. 1998. GFRa-4 and the tyrosine kinase Ret form a functional receptor complex for persephin. Curr. Biol. 8:1019-1022.
  • 21
    • 37549033163 scopus 로고    scopus 로고
    • Knockdown of the DNA repair and redox signaling protein Ape1/Ref-1 blocks ovarian cancer cell and tumor growth
    • Fishel, M. L., Y. He, A. M. Reed, H. Chin-Sinex, G. D. Hutchins, M. S. Mendonca, and M. R. Kelley. 2008. Knockdown of the DNA repair and redox signaling protein Ape1/Ref-1 blocks ovarian cancer cell and tumor growth. DNA Repair 7:177-186.
    • (2008) DNA Repair , vol.7 , pp. 177-186
    • Fishel, M.L.1    He, Y.2    Reed, A.M.3    Chin-Sinex, H.4    Hutchins, G.D.5    Mendonca, M.S.6    Kelley, M.R.7
  • 22
    • 0142219356 scopus 로고    scopus 로고
    • Studies of apurinic/apyrimidinic endonuclease/ref-1 expression in epithelial ovarian cancer: Correlations with tumor progression and platinum resistance
    • Freitas, S, D. H. Moore, H. Michael, and M. R. Kelley. 2003. Studies of apurinic/apyrimidinic endonuclease/ref-1 expression in epithelial ovarian cancer: correlations with tumor progression and platinum resistance. Clin. Cancer Res. 9:4689-4694.
    • (2003) Clin. Cancer Res , vol.9 , pp. 4689-4694
    • Freitas, S.1    Moore, D.H.2    Michael, H.3    Kelley, M.R.4
  • 23
    • 0033740986 scopus 로고    scopus 로고
    • Human APE/Ref-1 protein
    • Fritz, G. 2000. Human APE/Ref-1 protein. Int. J. Biochem. Cell Biol. 32:925-929.
    • (2000) Int. J. Biochem. Cell Biol , vol.32 , pp. 925-929
    • Fritz, G.1
  • 24
    • 0242299711 scopus 로고    scopus 로고
    • APE/Ref-1 and the mammalian response to genotoxic stress
    • Fritz, G., S. Grosch, M. Tomicic, and B. Kaina. 2003. APE/Ref-1 and the mammalian response to genotoxic stress. Toxicology 193:67-78.
    • (2003) Toxicology , vol.193 , pp. 67-78
    • Fritz, G.1    Grosch, S.2    Tomicic, M.3    Kaina, B.4
  • 25
    • 0033611583 scopus 로고    scopus 로고
    • Phosphorylation of the DNA repair protein APE/REF-1 by CKII affects redox regulation of AP-1
    • Fritz, G., and B. Kaina. 1999. Phosphorylation of the DNA repair protein APE/REF-1 by CKII affects redox regulation of AP-1. Oncogene 18:1033-1040.
    • (1999) Oncogene , vol.18 , pp. 1033-1040
    • Fritz, G.1    Kaina, B.2
  • 26
    • 0037331196 scopus 로고    scopus 로고
    • Implication of Ref-1 in the repression of renin gene transcription by intracellular calcium
    • Fuchs, S., J. Philippe, P. Corvol, and F. Pinet. 2003. Implication of Ref-1 in the repression of renin gene transcription by intracellular calcium. J. Hy-pertens. 21:327-335.
    • (2003) J. Hy-pertens , vol.21 , pp. 327-335
    • Fuchs, S.1    Philippe, J.2    Corvol, P.3    Pinet, F.4
  • 27
    • 22044451437 scopus 로고    scopus 로고
    • The role of glial cell line-derived neuro-trophic factor (GDNF) and integrins for invasion and metastasis in human pancreatic cancer cells
    • Funahashi, H., Y. Okada, H. Sawai, H. Takahashi, Y. Matsuo, H. Takeyama, and T. Manabe. 2005. The role of glial cell line-derived neuro-trophic factor (GDNF) and integrins for invasion and metastasis in human pancreatic cancer cells. J. Surg. Oncol. 91:77-83.
    • (2005) J. Surg. Oncol , vol.91 , pp. 77-83
    • Funahashi, H.1    Okada, Y.2    Sawai, H.3    Takahashi, H.4    Matsuo, Y.5    Takeyama, H.6    Manabe, T.7
  • 28
    • 0043095440 scopus 로고    scopus 로고
    • Alteration of integrin expression by glial cell line-derived neurotrophic factor (GDNF) in human pancreatic cancer cells
    • Funahashi, H., H. Takeyama, H. Sawai, A, Furuta, M. Sato, Y. Okada, T. Hayakawa, M. Tanaka, and T. Manabe. 2003. Alteration of integrin expression by glial cell line-derived neurotrophic factor (GDNF) in human pancreatic cancer cells. Pancreas 27:190-196.
    • (2003) Pancreas , vol.27 , pp. 190-196
    • Funahashi, H.1    Takeyama, H.2    Sawai, H.3    Furuta, A.4    Sato, M.5    Okada, Y.6    Hayakawa, T.7    Tanaka, M.8    Manabe, T.9
  • 30
    • 0033999274 scopus 로고    scopus 로고
    • Expression of matrix metalloproteinases and the tissue inhibitors of metalloproteinases and their local invasiveness and metastasis in Chinese human pancreatic cancer
    • Gong, Y. L., G. M. Xu, W. D. Huang, and L. B. Chen. 2000. Expression of matrix metalloproteinases and the tissue inhibitors of metalloproteinases and their local invasiveness and metastasis in Chinese human pancreatic cancer. J. Surg. Oncol. 73:95-99.
    • (2000) J. Surg. Oncol , vol.73 , pp. 95-99
    • Gong, Y.L.1    Xu, G.M.2    Huang, W.D.3    Chen, L.B.4
  • 31
    • 0029080314 scopus 로고
    • Expression and in-situ localization of genes coding for extracellular matrix proteins and extracellular matrix degrading proteases in pancreatic cancer
    • Gress, T. M, F. Muller-Pillasch, M. M. Lerch, H. Friess, M. Buchler, and G. Adler. 1995. Expression and in-situ localization of genes coding for extracellular matrix proteins and extracellular matrix degrading proteases in pancreatic cancer. Int. J. Cancer 62:407-413.
    • (1995) Int. J. Cancer , vol.62 , pp. 407-413
    • Gress, T.M.1    Muller-Pillasch, F.2    Lerch, M.M.3    Friess, H.4    Buchler, M.5    Adler, G.6
  • 32
    • 0032188756 scopus 로고    scopus 로고
    • Apurinic endonuclease (Ref-1) is induced in mammalian cells by oxidative stress and involved in clastogenic adaptation
    • Grosch, S., G. Fritz, and B. Kaina. 1998. Apurinic endonuclease (Ref-1) is induced in mammalian cells by oxidative stress and involved in clastogenic adaptation. Cancer Res. 58:4410-4416.
    • (1998) Cancer Res , vol.58 , pp. 4410-4416
    • Grosch, S.1    Fritz, G.2    Kaina, B.3
  • 33
    • 11144230576 scopus 로고    scopus 로고
    • Loss of redox factor 1 decreases NF-κB activity and increases susceptibility of endothelial cells to apoptosis
    • Guan, Z., D. Basi, Q. Li, A. Mariash, Y. F. Xia, J. G. Geng, E. Kao, and J. L. Hall. 2005. Loss of redox factor 1 decreases NF-κB activity and increases susceptibility of endothelial cells to apoptosis. Arterioscler. Thromb. Vase. Biol. 25:96-101.
    • (2005) Arterioscler. Thromb. Vase. Biol , vol.25 , pp. 96-101
    • Guan, Z.1    Basi, D.2    Li, Q.3    Mariash, A.4    Xia, Y.F.5    Geng, J.G.6    Kao, E.7    Hall, J.L.8
  • 34
    • 0035933483 scopus 로고    scopus 로고
    • Overex-pression of Ref-1 inhibits hypoxia and tumor necrosis factor-induced endothelial cell apoptosis through nuclear factor-κB-independent and -dependent pathways
    • Hall, J. L., X. Wang, A, Van, Y. Zhao, and G. H. Gibbons. 2001. Overex-pression of Ref-1 inhibits hypoxia and tumor necrosis factor-induced endothelial cell apoptosis through nuclear factor-κB-independent and -dependent pathways. Circ. Res. 88:1247-1253.
    • (2001) Circ. Res , vol.88 , pp. 1247-1253
    • Hall, J.L.1    Wang, X.2    Van, A.3    Zhao, Y.4    Gibbons, G.H.5
  • 36
    • 0030936568 scopus 로고    scopus 로고
    • AP-1 transcriptional activity is regulated by a direct association between thioredoxin and Ref-1
    • Hirota, K., M. Matsui, S. Iwata, A. Nishiyama, K. Mori, and J. Yodoi. 1997. AP-1 transcriptional activity is regulated by a direct association between thioredoxin and Ref-1. Proc. Natl. Acad. Sci. USA 94:3633-3638.
    • (1997) Proc. Natl. Acad. Sci. USA , vol.94 , pp. 3633-3638
    • Hirota, K.1    Matsui, M.2    Iwata, S.3    Nishiyama, A.4    Mori, K.5    Yodoi, J.6
  • 37
    • 0035879047 scopus 로고    scopus 로고
    • Activation of APE/Ref-1 redox activity is mediated by reactive oxygen species and PKC phosphorylation
    • Hsieh, M. M., V. Hegde, M. R. Kelley, and W. A. Deutsch. 2001. Activation of APE/Ref-1 redox activity is mediated by reactive oxygen species and PKC phosphorylation. Nucleic Acids Res. 29:3116-3122.
    • (2001) Nucleic Acids Res , vol.29 , pp. 3116-3122
    • Hsieh, M.M.1    Hegde, V.2    Kelley, M.R.3    Deutsch, W.A.4
  • 38
    • 0029753008 scopus 로고    scopus 로고
    • Activation of hypoxia-inducible transcription factor depends primarily upon redox-sensitive stabilization of its alpha subunit
    • Huang, L. E., Z. Arany, D. M. Livingston, and H. F. Bunn. 1996. Activation of hypoxia-inducible transcription factor depends primarily upon redox-sensitive stabilization of its alpha subunit. J. Biol. Chem. 271:32253-32259.
    • (1996) J. Biol. Chem , vol.271 , pp. 32253-32259
    • Huang, L.E.1    Arany, Z.2    Livingston, D.M.3    Bunn, H.F.4
  • 40
    • 0033923815 scopus 로고    scopus 로고
    • Requirement for human AP endonuclease 1 for repair of 3'-blocking damage at DNA single-strand breaks induced by reactive oxygen species
    • Izumi, T., T. K. Hazra, I. Boldogh, A. E. Tomkinson, M. S. Park, S. Ikeda, and S. Mitra. 2000. Requirement for human AP endonuclease 1 for repair of 3'-blocking damage at DNA single-strand breaks induced by reactive oxygen species. Carcinogenesis 21:1329-1334.
    • (2000) Carcinogenesis , vol.21 , pp. 1329-1334
    • Izumi, T.1    Hazra, T.K.2    Boldogh, I.3    Tomkinson, A.E.4    Park, M.S.5    Ikeda, S.6    Mitra, S.7
  • 41
    • 0030478864 scopus 로고    scopus 로고
    • Negative regulation of the major human AP-endonuclease, a multifunctional protein
    • Izumi, T., W. D. Henner, and S. Mitra. 1996. Negative regulation of the major human AP-endonuclease, a multifunctional protein. Biochemistry 35:14679-14683.
    • (1996) Biochemistry , vol.35 , pp. 14679-14683
    • Izumi, T.1    Henner, W.D.2    Mitra, S.3
  • 43
    • 0034905642 scopus 로고    scopus 로고
    • Elevated and altered expression of the multifunctional DNA base excision repair and redox enzyme Ape1/ref-1 in prostate cancer
    • Kelley, M. R., L. Cheng, R. Foster, R. Tritt, J. Jiang, J. Broshears, and M. Koch. 2001. Elevated and altered expression of the multifunctional DNA base excision repair and redox enzyme Ape1/ref-1 in prostate cancer. Clin. Cancer Res. 7:824-830.
    • (2001) Clin. Cancer Res , vol.7 , pp. 824-830
    • Kelley, M.R.1    Cheng, L.2    Foster, R.3    Tritt, R.4    Jiang, J.5    Broshears, J.6    Koch, M.7
  • 44
    • 1642499508 scopus 로고    scopus 로고
    • Localized striatal delivery of GDNF as a treatment for Parkinson disease
    • Kirik, D., B. Georgievska, and A, Bjorklund. 2004. Localized striatal delivery of GDNF as a treatment for Parkinson disease. Nat. Neurosci. 7:105-110.
    • (2004) Nat. Neurosci , vol.7 , pp. 105-110
    • Kirik, D.1    Georgievska, B.2    Bjorklund, A.3
  • 45
    • 0030916372 scopus 로고    scopus 로고
    • Evidence of reduced DNA repair in amyotrophic lateral sclerosis brain tissue
    • Kisby, G. E., J. Milne, and C. Sweatt. 1997. Evidence of reduced DNA repair in amyotrophic lateral sclerosis brain tissue. Neuroreport 8:1337-1340.
    • (1997) Neuroreport , vol.8 , pp. 1337-1340
    • Kisby, G.E.1    Milne, J.2    Sweatt, C.3
  • 47
    • 0036464533 scopus 로고    scopus 로고
    • Human AP-endonuclease 1 and hnRNP-L interact with a nCaRE-like repressor element in the AP-endonuclease 1 promoter
    • Kuninger, D. T., T. Izumi, J. Papaconstantinou, and S. Mitra. 2002. Human AP-endonuclease 1 and hnRNP-L interact with a nCaRE-like repressor element in the AP-endonuclease 1 promoter. Nucleic Acids Res. 30:823-829.
    • (2002) Nucleic Acids Res , vol.30 , pp. 823-829
    • Kuninger, D.T.1    Izumi, T.2    Papaconstantinou, J.3    Mitra, S.4
  • 48
    • 12144287121 scopus 로고    scopus 로고
    • Transcription factors NF-YA regulate the induction of human OGG1 following DNA-alkylating agent methylmethane sulfonate (MMS) treatment
    • Lee, M. R., S. H. Kim, H. J. Cho, K. Y. Lee, A. R. Moon, H. G. Jeong, J. S. Lee, J. W. Hyun, M. H. Chung, and H. J. You. 2004. Transcription factors NF-YA regulate the induction of human OGG1 following DNA-alkylating agent methylmethane sulfonate (MMS) treatment. J. Biol. Chem. 279: 9857-9866.
    • (2004) J. Biol. Chem , vol.279 , pp. 9857-9866
    • Lee, M.R.1    Kim, S.H.2    Cho, H.J.3    Lee, K.Y.4    Moon, A.R.5    Jeong, H.G.6    Lee, J.S.7    Hyun, J.W.8    Chung, M.H.9    You, H.J.10
  • 49
    • 0034979216 scopus 로고    scopus 로고
    • Oxidative cellular damage and the reduction of APE/Ref-1 expression after experimental traumatic brain injury
    • Lewen, A., T. Sugawara, Y. Gasche, M. Fujimura, and P. H. Chan. 2001. Oxidative cellular damage and the reduction of APE/Ref-1 expression after experimental traumatic brain injury. Neurobiol. Dis. 8:380-390.
    • (2001) Neurobiol. Dis , vol.8 , pp. 380-390
    • Lewen, A.1    Sugawara, T.2    Gasche, Y.3    Fujimura, M.4    Chan, P.H.5
  • 50
    • 0027285510 scopus 로고
    • GDNF: A glial cell line-derived neurotrophic factor for midbrain dopami-nergic neurons
    • Lin, L. F., D. H. Doherty, J. D. Lile, S. Bektesh, and F. Collins. 1993. GDNF: a glial cell line-derived neurotrophic factor for midbrain dopami-nergic neurons. Science 260:1130-1132.
    • (1993) Science , vol.260 , pp. 1130-1132
    • Lin, L.F.1    Doherty, D.H.2    Lile, J.D.3    Bektesh, S.4    Collins, F.5
  • 51
    • 0033932552 scopus 로고    scopus 로고
    • Expression and alternative splicing of mouse Gfra4 suggest roles in endocrine cell development
    • Lindahl, M., T. Tim musk. J. Rossi, M. Saarma, and M. S. Airaksinen. 2000. Expression and alternative splicing of mouse Gfra4 suggest roles in endocrine cell development. Mol. Cell Neurosci. 15:522-533.
    • (2000) Mol. Cell Neurosci , vol.15 , pp. 522-533
    • Lindahl, M.1    Tim musk, T.2    Rossi, J.3    Saarma, M.4    Airaksinen, M.S.5
  • 52
    • 0015504248 scopus 로고
    • Rate of depurination of native deoxyri-bonucleic acid
    • Lindahl, T., and B. Nyberg. 1972. Rate of depurination of native deoxyri-bonucleic acid. Biochemistry 11:3610-3618.
    • (1972) Biochemistry , vol.11 , pp. 3610-3618
    • Lindahl, T.1    Nyberg, B.2
  • 53
    • 0023015325 scopus 로고
    • Mutagenesis by apurinic/apyrimidinic sites
    • Loeb, L. A., and B. D. Preston. 1986. Mutagenesis by apurinic/apyrimidinic sites. Annu. Rev. Genet. 20:201-230.
    • (1986) Annu. Rev. Genet , vol.20 , pp. 201-230
    • Loeb, L.A.1    Preston, B.D.2
  • 54
    • 0031720426 scopus 로고    scopus 로고
    • Ludwig, D. L., M. A, Maclnnes, Y. Takiguchi, P. E. Purtymun, M. Henrie, M. Flannery, J. Meneses, R. A. Pedersen, and D. J. Chen. 1998. A murine AP-endonuclease gene-targeted deficiency with post-implantation embryonic progression and ionizing radiation sensitivity. Mutat. Res. 409:17-29.
    • Ludwig, D. L., M. A, Maclnnes, Y. Takiguchi, P. E. Purtymun, M. Henrie, M. Flannery, J. Meneses, R. A. Pedersen, and D. J. Chen. 1998. A murine AP-endonuclease gene-targeted deficiency with post-implantation embryonic progression and ionizing radiation sensitivity. Mutat. Res. 409:17-29.
  • 55
    • 0026715172 scopus 로고
    • Thioredoxin regulates the DNA binding activity of NF-κB by reduction of a disulphide bond involving cysteine 62
    • Matthews, J. R., N. Wakasugi, J. L. Virelizier, J. Yodoi, and R. T. Hay. 1992. Thioredoxin regulates the DNA binding activity of NF-κB by reduction of a disulphide bond involving cysteine 62. Nucleic Acids Res. 20:3821-3830.
    • (1992) Nucleic Acids Res , vol.20 , pp. 3821-3830
    • Matthews, J.R.1    Wakasugi, N.2    Virelizier, J.L.3    Yodoi, J.4    Hay, R.T.5
  • 57
    • 0027963233 scopus 로고
    • Two different cellular redox systems regulate the DNA-binding activity of the p50 subunit of NF-κB in vitro
    • Mitomo, K., K. Nakayama, K. Fujimoto, X. Sun, S. Seki, and K. Yamamoto. 1994. Two different cellular redox systems regulate the DNA-binding activity of the p50 subunit of NF-κB in vitro. Gene 145:197-203.
    • (1994) Gene , vol.145 , pp. 197-203
    • Mitomo, K.1    Nakayama, K.2    Fujimoto, K.3    Sun, X.4    Seki, S.5    Yamamoto, K.6
  • 58
    • 0034719372 scopus 로고    scopus 로고
    • Mol, C. D., T. Izumi, S. Mitra, and J. A, Tainer. 2000. DNA-bound structures and mutants reveal abasic DNA binding by APE1 and DNA repair coordination. Nature 403:451-456.
    • Mol, C. D., T. Izumi, S. Mitra, and J. A, Tainer. 2000. DNA-bound structures and mutants reveal abasic DNA binding by APE1 and DNA repair coordination. Nature 403:451-456.
  • 59
    • 0033961301 scopus 로고    scopus 로고
    • Alterations in the expression of the DNA repair/redox enzyme APE/Ref-1 in epithelial ovarian cancers
    • Moore, D. H., H. Michael, R. Tritt, S. H. Parsons, and M. R. Kelley. 2000. Alterations in the expression of the DNA repair/redox enzyme APE/Ref-1 in epithelial ovarian cancers. Clin. Cancer Res. 6:602-609.
    • (2000) Clin. Cancer Res , vol.6 , pp. 602-609
    • Moore, D.H.1    Michael, H.2    Tritt, R.3    Parsons, S.H.4    Kelley, M.R.5
  • 61
    • 0036177290 scopus 로고    scopus 로고
    • Histologic features of venous invasion, expression of vascular endothelial growth factor and matrix metalloproteinase-2 and matrix metalloprotein-ase-9, and the relation with liver metastasis in pancreatic cancer
    • Nagakawa, Y., T. Aoki, K. Kasuya, A, Tsuchida, and Y. Koyanagi. 2002. Histologic features of venous invasion, expression of vascular endothelial growth factor and matrix metalloproteinase-2 and matrix metalloprotein-ase-9, and the relation with liver metastasis in pancreatic cancer. Pancreas 24:169-178.
    • (2002) Pancreas , vol.24 , pp. 169-178
    • Nagakawa, Y.1    Aoki, T.2    Kasuya, K.3    Tsuchida, A.4    Koyanagi, Y.5
  • 62
    • 0029869717 scopus 로고    scopus 로고
    • Clinical significance of carcinoma invasion of the extrapancreatic nerve plexus in pancreatic cancer
    • Nakao, A., A. Harada, T. Nonami, T. Kaneko, and H. Takagi. 1996. Clinical significance of carcinoma invasion of the extrapancreatic nerve plexus in pancreatic cancer. Pancreas 12:357-361.
    • (1996) Pancreas , vol.12 , pp. 357-361
    • Nakao, A.1    Harada, A.2    Nonami, T.3    Kaneko, T.4    Takagi, H.5
  • 64
    • 0042328053 scopus 로고    scopus 로고
    • Glial cell-derived neurotrophic factor upregulates the expression and activation of matrix metalloproteinase-9 in human pancreatic cancer
    • Okada, Y., G. Eibl, J. P. Duffy, H. A. Reber, and O. J. Hines. 2003. Glial cell-derived neurotrophic factor upregulates the expression and activation of matrix metalloproteinase-9 in human pancreatic cancer. Surgery 134: 293-299.
    • (2003) Surgery , vol.134 , pp. 293-299
    • Okada, Y.1    Eibl, G.2    Duffy, J.P.3    Reber, H.A.4    Hines, O.J.5
  • 66
    • 0032567807 scopus 로고    scopus 로고
    • Mutant AP endonuclease in patients with amyotro-phic lateral sclerosis
    • Olkowski, Z. L. 1998. Mutant AP endonuclease in patients with amyotro-phic lateral sclerosis. Neuroreport 9:239-242.
    • (1998) Neuroreport , vol.9 , pp. 239-242
    • Olkowski, Z.L.1
  • 67
    • 0028244814 scopus 로고
    • Stable expression in rat glioma cells of sense and antisense nucleic acids to a human multifunctional DNA repair enzyme, APEX nuclease
    • Ono, Y., T. Furuta, T. Ohmoto, K. Akiyama, and S. Seki. 1994. Stable expression in rat glioma cells of sense and antisense nucleic acids to a human multifunctional DNA repair enzyme, APEX nuclease. Mutat. Res. 315:55-63.
    • (1994) Mutat. Res , vol.315 , pp. 55-63
    • Ono, Y.1    Furuta, T.2    Ohmoto, T.3    Akiyama, K.4    Seki, S.5
  • 68
    • 0028823440 scopus 로고
    • Relationship between expression of a major apurinic/apyrimidinic endonuclease (APEX nuclease) and susceptibility to genotoxic agents in human glioma cell lines
    • Ono, Y., K. Matsumoto, T. Furuta, T. Ohmoto, K. Akiyama, and S. Seki. 1995. Relationship between expression of a major apurinic/apyrimidinic endonuclease (APEX nuclease) and susceptibility to genotoxic agents in human glioma cell lines. J. Neurooncol. 25:183-192.
    • (1995) J. Neurooncol , vol.25 , pp. 183-192
    • Ono, Y.1    Matsumoto, K.2    Furuta, T.3    Ohmoto, T.4    Akiyama, K.5    Seki, S.6
  • 69
    • 0038655553 scopus 로고    scopus 로고
    • Cysteine 64 of Ref-1 is not essential for redox regulation of AP-1 DNA binding
    • Ordway, J. M., D. Eberhart, and T. Curran. 2003. Cysteine 64 of Ref-1 is not essential for redox regulation of AP-1 DNA binding. Mol. Cell. Biol. 23:4257-4266.
    • (2003) Mol. Cell. Biol , vol.23 , pp. 4257-4266
    • Ordway, J.M.1    Eberhart, D.2    Curran, T.3
  • 71
    • 0345352666 scopus 로고    scopus 로고
    • GDNF promotes tubulogenesis of GFRαl-expressing MDCK cells by Src-mediated phosphorylation of Met receptor tyrosine kinase
    • Popsueva, A., D. Poteryaev, E. Arighi, X. Meng, A. Angers-Loustau, D. Kaplan, M. Saarma, and H. Sariola. 2003. GDNF promotes tubulogenesis of GFRαl-expressing MDCK cells by Src-mediated phosphorylation of Met receptor tyrosine kinase. J. Cell Biol. 161:119-129.
    • (2003) J. Cell Biol , vol.161 , pp. 119-129
    • Popsueva, A.1    Poteryaev, D.2    Arighi, E.3    Meng, X.4    Angers-Loustau, A.5    Kaplan, D.6    Saarma, M.7    Sariola, H.8
  • 73
    • 0032574770 scopus 로고    scopus 로고
    • Activation of apurinic/apyrimidinic endonuclease in human cells by reactive oxygen species and its correlation with their adaptive response to genotoxicity of free radicals
    • Ramana, C. V., I. Boldogh, T. Izumi, and S. Mitra. 1998. Activation of apurinic/apyrimidinic endonuclease in human cells by reactive oxygen species and its correlation with their adaptive response to genotoxicity of free radicals. Proc. Natl. Acad. Sci. USA 95:5061-5066.
    • (1998) Proc. Natl. Acad. Sci. USA , vol.95 , pp. 5061-5066
    • Ramana, C.V.1    Boldogh, I.2    Izumi, T.3    Mitra, S.4
  • 74
    • 0035266131 scopus 로고    scopus 로고
    • Altered expression of Ape1/ref-1 in germ cell tumors and overexpression in NT2 cells confers resistance to bleomycin and radiation
    • Robertson, K. A., H. A. Bullock, Y. Xu, R. Tritt, E. Zimmerman, T. M. Ulbright, R. S. Foster, L. H. Einhorn, and M. R. Kelley. 2001. Altered expression of Ape1/ref-1 in germ cell tumors and overexpression in NT2 cells confers resistance to bleomycin and radiation. Cancer Res. 61:2220-2225.
    • (2001) Cancer Res , vol.61 , pp. 2220-2225
    • Robertson, K.A.1    Bullock, H.A.2    Xu, Y.3    Tritt, R.4    Zimmerman, E.5    Ulbright, T.M.6    Foster, R.S.7    Einhorn, L.H.8    Kelley, M.R.9
  • 75
    • 0033563301 scopus 로고    scopus 로고
    • Other neurotrophic factors: Glial cell line-derived neurotrophic factor (GDNF)
    • Saarma, M., and H. Sariola. 1999. Other neurotrophic factors: glial cell line-derived neurotrophic factor (GDNF). Microsc. Res. Tech. 45:292-302.
    • (1999) Microsc. Res. Tech , vol.45 , pp. 292-302
    • Saarma, M.1    Sariola, H.2
  • 76
    • 0037328721 scopus 로고    scopus 로고
    • Oxidative damage and reduction of redox factor-1 expression after transient spinal cord ischemia in rabbits
    • Sakurai, M., T. Nagata, K. Abe, T. Horinouchi, Y. Itoyama, and K. Taba-yashi. 2003. Oxidative damage and reduction of redox factor-1 expression after transient spinal cord ischemia in rabbits. J. Vase. Surg. 37:446-452.
    • (2003) J. Vase. Surg , vol.37 , pp. 446-452
    • Sakurai, M.1    Nagata, T.2    Abe, K.3    Horinouchi, T.4    Itoyama, Y.5    Taba-yashi, K.6
  • 77
    • 0029901727 scopus 로고    scopus 로고
    • Sanchez, M. P., I. Silos-Santiago, J. Frisen, B. He, S. A, Lira, and M. Barbacid. 1996. Renal agenesis and the absence of enteric neurons in mice lacking GDNF. Nature 382:70-73.
    • Sanchez, M. P., I. Silos-Santiago, J. Frisen, B. He, S. A, Lira, and M. Barbacid. 1996. Renal agenesis and the absence of enteric neurons in mice lacking GDNF. Nature 382:70-73.
  • 78
    • 0142106351 scopus 로고    scopus 로고
    • Novel functions and signalling pathways for GDNF
    • Sariola, H., and M. Saarma. 2003. Novel functions and signalling pathways for GDNF. J. Cell Sci. 116:3855-3862.
    • (2003) J. Cell Sci , vol.116 , pp. 3855-3862
    • Sariola, H.1    Saarma, M.2
  • 79
    • 29244490072 scopus 로고    scopus 로고
    • The G691S RET polymorphism increases glial cell line-derived neurotrophic factor-induced pancreatic cancer cell invasion by amplifying mitogen-activated protein kinase signaling
    • Sawai, H., Y. Okada, K. Kazanjian, J. Kim, S. Hasan, O. J. Hines, H. A. Reber, D. S. Hoon, and G. Eibl. 2005. The G691S RET polymorphism increases glial cell line-derived neurotrophic factor-induced pancreatic cancer cell invasion by amplifying mitogen-activated protein kinase signaling. Cancer Res. 65:11536-11544.
    • (2005) Cancer Res , vol.65 , pp. 11536-11544
    • Sawai, H.1    Okada, Y.2    Kazanjian, K.3    Kim, J.4    Hasan, S.5    Hines, O.J.6    Reber, H.A.7    Hoon, D.S.8    Eibl, G.9
  • 81
    • 0035188727 scopus 로고    scopus 로고
    • How matrix metalloproteinases regulate cell behavior
    • Sternlicht, M. D., and Z. Werb. 2001. How matrix metalloproteinases regulate cell behavior. Annu. Rev. Cell Dev. Biol. 17:463-516.
    • (2001) Annu. Rev. Cell Dev. Biol , vol.17 , pp. 463-516
    • Sternlicht, M.D.1    Werb, Z.2
  • 82
    • 3042774318 scopus 로고    scopus 로고
    • Glial cell line-derived neurotrophic factor enhances nuclear factor-κB activity and invasive potential in human pancreatic cancer cells
    • Takahashi, H., H. Funahashi, H. Sawai, M. Sakamoto, Y. Matsuo, M. Yamamoto, Y. Okada, T. Hayakawa, and T. Manabe. 2004. Glial cell line-derived neurotrophic factor enhances nuclear factor-κB activity and invasive potential in human pancreatic cancer cells. Pancreas 29:22-27.
    • (2004) Pancreas , vol.29 , pp. 22-27
    • Takahashi, H.1    Funahashi, H.2    Sawai, H.3    Sakamoto, M.4    Matsuo, Y.5    Yamamoto, M.6    Okada, Y.7    Hayakawa, T.8    Manabe, T.9
  • 83
    • 0032563635 scopus 로고    scopus 로고
    • Immunohistochemical localization of redox factor-1 (Ref-1) in Alzheimer's hippocampus
    • Tan, Z., N. Sun, and S. S. Schreiber. 1998. Immunohistochemical localization of redox factor-1 (Ref-1) in Alzheimer's hippocampus. Neuroreport 9:2749-2752.
    • (1998) Neuroreport , vol.9 , pp. 2749-2752
    • Tan, Z.1    Sun, N.2    Schreiber, S.S.3
  • 84
    • 0034994827 scopus 로고    scopus 로고
    • Histology-specific expression of a DNA repair protein in pediatric rhabdomyosarcomas
    • Thomson, B., R. Tritt, M. Davis, and M. R. Kelley. 2001. Histology-specific expression of a DNA repair protein in pediatric rhabdomyosarcomas. J. Pediatr. Hematol. Oncol. 23:234-239.
    • (2001) J. Pediatr. Hematol. Oncol , vol.23 , pp. 234-239
    • Thomson, B.1    Tritt, R.2    Davis, M.3    Kelley, M.R.4
  • 85
    • 0028834063 scopus 로고
    • Protection and repair of the nigrostriatal dopaminergic system by GDNF in vivo
    • Tomac, A., E. Lindqvist, L. F. Lin, S. O. Ogren, D. Young, B. J. Hoffer, and L. Olson. 1995. Protection and repair of the nigrostriatal dopaminergic system by GDNF in vivo. Nature 373:335-339.
    • (1995) Nature , vol.373 , pp. 335-339
    • Tomac, A.1    Lindqvist, E.2    Lin, L.F.3    Ogren, S.O.4    Young, D.5    Hoffer, B.J.6    Olson, L.7
  • 87
    • 0030915959 scopus 로고    scopus 로고
    • Complementary and overlapping expression of glial cell line-derived neurotrophic factor (GDNF), c-ret proto-oncogene, and GDNF receptor-alpha indicates multiple mechanisms of trophic actions in the adult rat CNS
    • Trupp, M., N. Belluardo, H. Funakoshi, and C. F. Ibanez. 1997. Complementary and overlapping expression of glial cell line-derived neurotrophic factor (GDNF), c-ret proto-oncogene, and GDNF receptor-alpha indicates multiple mechanisms of trophic actions in the adult rat CNS. J. Neurosci. 17:3554-3567.
    • (1997) J. Neurosci , vol.17 , pp. 3554-3567
    • Trupp, M.1    Belluardo, N.2    Funakoshi, H.3    Ibanez, C.F.4
  • 88
    • 0033597817 scopus 로고    scopus 로고
    • Ret-dependent and -independent mechanisms of glial cell line-derived neurotrophic factor signaling in neuronal cells
    • Trupp, M., R. Scott, S. R. Whittemore, and C. F. Ibanez. 1999. Ret-dependent and -independent mechanisms of glial cell line-derived neurotrophic factor signaling in neuronal cells. J. Biol. Chem. 274:20885-20894.
    • (1999) J. Biol. Chem , vol.274 , pp. 20885-20894
    • Trupp, M.1    Scott, R.2    Whittemore, S.R.3    Ibanez, C.F.4
  • 89
    • 12344291209 scopus 로고    scopus 로고
    • The multifunctional DNA repair/redox enzyme Ape1/Ref-1 promotes survival of neurons after oxidative stress
    • Vasko, M. R., C. Guo, and M. R. Kelley. 2005. The multifunctional DNA repair/redox enzyme Ape1/Ref-1 promotes survival of neurons after oxidative stress. DNA Repair 4:367-379.
    • (2005) DNA Repair , vol.4 , pp. 367-379
    • Vasko, M.R.1    Guo, C.2    Kelley, M.R.3
  • 90
    • 3442876128 scopus 로고    scopus 로고
    • Activation of phosphatidylinositol 3-kinase and extracellular signal-regulated kinase is required for glial cell line-derived neurotrophic factor-induced migration and invasion of pancreatic carcinoma cells
    • Veit, C., F. Genze, A. Menke, S. Hoeffert, T. M. Gress, P. Gierschik, and K. Giehl. 2004. Activation of phosphatidylinositol 3-kinase and extracellular signal-regulated kinase is required for glial cell line-derived neurotrophic factor-induced migration and invasion of pancreatic carcinoma cells. Cancer Res. 64:5291-5300.
    • (2004) Cancer Res , vol.64 , pp. 5291-5300
    • Veit, C.1    Genze, F.2    Menke, A.3    Hoeffert, S.4    Gress, T.M.5    Gierschik, P.6    Giehl, K.7
  • 91
    • 0028596574 scopus 로고
    • A role for the human DNA repair enzyme HAP1 in cellular protection against DNA-damaging agents and hypoxic stress
    • Walker, L. J., R. B. Craig, A. L. Harris, and I. D. Hickson. 1994. A role for the human DNA repair enzyme HAP1 in cellular protection against DNA-damaging agents and hypoxic stress. Nucleic Acids Res. 22:4884-4889.
    • (1994) Nucleic Acids Res , vol.22 , pp. 4884-4889
    • Walker, L.J.1    Craig, R.B.2    Harris, A.L.3    Hickson, I.D.4
  • 92
    • 0027324056 scopus 로고
    • Identification of residues in the human DNA repair enzyme HAP1 (Ref-1) that are essential for redox regulation of Jun DNA binding
    • Walker, L. J., C. N. Robson, E. Black, D. Gillespie, and I. D. Hickson. 1993. Identification of residues in the human DNA repair enzyme HAP1 (Ref-1) that are essential for redox regulation of Jun DNA binding. Mol. Cell. Biol. 13:5370-5376.
    • (1993) Mol. Cell. Biol , vol.13 , pp. 5370-5376
    • Walker, L.J.1    Robson, C.N.2    Black, E.3    Gillespie, D.4    Hickson, I.D.5
  • 94
    • 4444327784 scopus 로고    scopus 로고
    • Human apurinic endonuclease 1 (APE1) expression and prognostic significance in osteosarcoma: Enhanced sensitivity of osteosarcoma to DNA-damaging agents using silencing RNA APE1 expression inhibition
    • Wang, D., M. Luo, and M. R. Kelley. 2004. Human apurinic endonuclease 1 (APE1) expression and prognostic significance in osteosarcoma: enhanced sensitivity of osteosarcoma to DNA-damaging agents using silencing RNA APE1 expression inhibition. Mol. Cancer Ther. 3:679-686.
    • (2004) Mol. Cancer Ther , vol.3 , pp. 679-686
    • Wang, D.1    Luo, M.2    Kelley, M.R.3
  • 95
    • 0030004546 scopus 로고    scopus 로고
    • Differential expression of the apurinic/apyrimidinic endonuclease (APE/ref-1) multifunctional DNA base excision repair gene during fetal development and in adult rat brain and testis
    • Wilson, T. M, S. A. Rivkees, W. A. Deutsch, and M. R. Kelley. 1996. Differential expression of the apurinic/apyrimidinic endonuclease (APE/ref-1) multifunctional DNA base excision repair gene during fetal development and in adult rat brain and testis. Mutat. Res. 362:237-248.
    • (1996) Mutat. Res , vol.362 , pp. 237-248
    • Wilson, T.M.1    Rivkees, S.A.2    Deutsch, W.A.3    Kelley, M.R.4
  • 96
    • 0026583944 scopus 로고
    • Identification and characterization of Ref-1, a nuclear protein that facilitates AP-1 DNA-binding activity
    • Xanthoudakis, S., and T. Curran. 1992. Identification and characterization of Ref-1, a nuclear protein that facilitates AP-1 DNA-binding activity. EMBO J. 11:653-665.
    • (1992) EMBO J , vol.11 , pp. 653-665
    • Xanthoudakis, S.1    Curran, T.2
  • 97
    • 0026714672 scopus 로고
    • Redox activation of Fos-Jun DNA binding activity is mediated by a DNA repair enzyme
    • Xanthoudakis, S., G. Miao, F. Wang, Y. C. Pan, and T. Curran. 1992. Redox activation of Fos-Jun DNA binding activity is mediated by a DNA repair enzyme. EMBO J. 11:3323-3335.
    • (1992) EMBO J , vol.11 , pp. 3323-3335
    • Xanthoudakis, S.1    Miao, G.2    Wang, F.3    Pan, Y.C.4    Curran, T.5
  • 98
    • 0031439376 scopus 로고    scopus 로고
    • The apurinic/apyrimidinic endonuclease (APE/ref-1) DNA repair enzyme is elevated in premalignant and malignant cervical cancer
    • Xu, Y., D. H. Moore, J. Broshears, L. Liu, T. M. Wilson, and M. R. Kelley. 1997. The apurinic/apyrimidinic endonuclease (APE/ref-1) DNA repair enzyme is elevated in premalignant and malignant cervical cancer. Anti-cancer Res. 17:3713-3719.
    • (1997) Anti-cancer Res , vol.17 , pp. 3713-3719
    • Xu, Y.1    Moore, D.H.2    Broshears, J.3    Liu, L.4    Wilson, T.M.5    Kelley, M.R.6
  • 99
    • 30344434348 scopus 로고    scopus 로고
    • Yang, S., K. Irani, S. E. Heffron, F. Jurnak, and F. L. Meyskens, Jr. 2005. Alterations in the expression of the apurinic/apyrimidinic endonuclease-1/redox factor-1 (APE/Ref-1) in human melanoma and identification of the therapeutic potential of resveratrol as an APE/Ref-1 inhibitor. Mol. Cancer Ther. 4:1923-1935.
    • Yang, S., K. Irani, S. E. Heffron, F. Jurnak, and F. L. Meyskens, Jr. 2005. Alterations in the expression of the apurinic/apyrimidinic endonuclease-1/redox factor-1 (APE/Ref-1) in human melanoma and identification of the therapeutic potential of resveratrol as an APE/Ref-1 inhibitor. Mol. Cancer Ther. 4:1923-1935.
  • 100
    • 36148930625 scopus 로고    scopus 로고
    • Yang, S., B. J. Misner, R. J. Chiu, and F. L. Meyskens, Jr. 2007. Redox effector factor-1, combined with reactive oxygen species, plays an important role in the transformation of JB6 cells. Carcinogenesis 28:2382-2390.
    • Yang, S., B. J. Misner, R. J. Chiu, and F. L. Meyskens, Jr. 2007. Redox effector factor-1, combined with reactive oxygen species, plays an important role in the transformation of JB6 cells. Carcinogenesis 28:2382-2390.
  • 102
    • 0036661219 scopus 로고    scopus 로고
    • Yeo, T. P., R. H. Hruban, S. D. Leach, R. E. Wilentz, T. A Sohn, S. E. Kern, C. A. Iacobuzio-Donahue, A. Maitra, M. Goggins, M. I. Canto, R. A. Abrams, D. Laheru, E. M. Jaffee, M. Hidalgo, and C. J. Yeo. 2002. Pancreatic cancer. Curr. Probl. Cancer 26:176-275.
    • Yeo, T. P., R. H. Hruban, S. D. Leach, R. E. Wilentz, T. A Sohn, S. E. Kern, C. A. Iacobuzio-Donahue, A. Maitra, M. Goggins, M. I. Canto, R. A. Abrams, D. Laheru, E. M. Jaffee, M. Hidalgo, and C. J. Yeo. 2002. Pancreatic cancer. Curr. Probl. Cancer 26:176-275.
  • 104
    • 6944236323 scopus 로고    scopus 로고
    • Ref-1/Ape is critical for formation of the hypoxia-inducible transcriptional complex on the hypoxic response element of the rat pulmonary artery endothelial cell VEGF gene
    • Ziel, K. A., C. C. Campbell, G. L. Wilson, and M. N. Gillespie. 2004. Ref-1/Ape is critical for formation of the hypoxia-inducible transcriptional complex on the hypoxic response element of the rat pulmonary artery endothelial cell VEGF gene. FASEB J. 18:986-988.
    • (2004) FASEB J , vol.18 , pp. 986-988
    • Ziel, K.A.1    Campbell, C.C.2    Wilson, G.L.3    Gillespie, M.N.4
  • 105
    • 51049091691 scopus 로고    scopus 로고
    • Small-molecule inhibitor of the AP endonuclease 1/REF-l E3330 inhibits pancreatic cancer cell growth and migration
    • Zou, G. M., and A. Maitra. 2008. Small-molecule inhibitor of the AP endonuclease 1/REF-l E3330 inhibits pancreatic cancer cell growth and migration. Mol. Cancer Ther. 7:2012-2021.
    • (2008) Mol. Cancer Ther , vol.7 , pp. 2012-2021
    • Zou, G.M.1    Maitra, A.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.