APE1/Ref-1 Regulates STAT3 Transcriptional Activity and APE1/Ref-1-STAT3 Dual-Targeting Effectively Inhibits Pancreatic Cancer Cell Survival

PLoS ONE

Volumn 7, Issue 10, 2012, Pages

  Cardoso, Angelo A ^a   Jiang, Yanlin ^a   Luo, Meihua ^a   Reed, April M ^a   Shahda, Safi ^a   He, Ying ^a   Maitra, Anirban ^b   Kelley, Mark R ^a   Fishel, Melissa L ^a  

^a INDIANA UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTINEOPLASTIC AGENT; CASPASE 3; DNA; E 3330; REDOX EFFECTOR FACTOR 1; STAT3 PROTEIN; UNCLASSIFIED DRUG;

ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; CANCER CELL; CELL FUNCTION; CELL MIGRATION; CELL PROLIFERATION; CELL SURVIVAL; CELL VIABILITY; CONTROLLED STUDY; DRUG TARGETING; GENE DISRUPTION; GENE MUTATION; GENE OVEREXPRESSION; GENE SILENCING; NONHUMAN; OXIDATION REDUCTION REACTION; PANCREAS CANCER; PHARMACOLOGICAL BLOCKING; PROTEIN DNA BINDING; SIGNAL TRANSDUCTION; TRANSCRIPTION REGULATION;

ADENOCARCINOMA; AMINOSALICYLIC ACIDS; APOPTOSIS; BENZENESULFONATES; BENZOQUINONES; CASPASE 3; CELL LINE, TUMOR; CELL PROLIFERATION; CYCLIC S-OXIDES; DNA-(APURINIC OR APYRIMIDINIC SITE) LYASE; GENE EXPRESSION REGULATION, NEOPLASTIC; GENE KNOCKDOWN TECHNIQUES; HUMANS; MOLECULAR TARGETED THERAPY; OXIDATION-REDUCTION; PANCREATIC NEOPLASMS; PROPIONATES; RNA, SMALL INTERFERING; SIGNAL TRANSDUCTION; STAT3 TRANSCRIPTION FACTOR; TRANSCRIPTION, GENETIC;

EID: 84867676774     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0047462     Document Type: Article

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