APE1/Ref-1 prevents oxidative inactivation of ERK for G1-to-S progression following lead acetate exposure

Toxicology

Volumn 305, Issue , 2013, Pages 120-129

  Wang, Yi Ting ^a   Tzeng, Der Wan ^a   Wang, Chun Yu ^a   Hong, Jing Yin ^a   Yang, Jia Ling ^a  

^a NATIONAL TSING HUA UNIVERSITY   (Taiwan)

Author keywords

APE1; Cyclin D1; ERK; Heavy metal; Oxidation

Indexed keywords

APURINIC APYRIMIDINIC ENDONUCLEASE 1; CYCLIN D1; CYSTEINE; DNA (APURINIC OR APYRIMIDINIC SITE) LYASE; E 3330; LEAD ACETATE; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE INHIBITOR; REACTIVE OXYGEN METABOLITE; REDOX EFFECTOR FACTOR 1; SMALL INTERFERING RNA; UNCLASSIFIED DRUG;

ARTICLE; CANCER CELL; CELL CYCLE G1 PHASE; CELL CYCLE PROGRESSION; CELL CYCLE S PHASE; CELL PROLIFERATION; CONTROLLED STUDY; CYTOTOXICITY; ENVIRONMENTAL EXPOSURE; ENZYME ACTIVITY; ENZYME INACTIVATION; HUMAN; HUMAN CELL; IN VITRO STUDY; LUNG CANCER; OXIDATION REDUCTION STATE; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; RECEPTOR UPREGULATION; SERUM; SIGNAL TRANSDUCTION;

3T3 CELLS; ANIMALS; BENZOQUINONES; BLOTTING, WESTERN; CELL LINE, TUMOR; CELL SURVIVAL; COLONY-FORMING UNITS ASSAY; CYSTEINE; DNA-(APURINIC OR APYRIMIDINIC SITE) LYASE; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; G1 PHASE; HUMANS; IMMUNOPRECIPITATION; MICE; MITOSIS; ORGANOMETALLIC COMPOUNDS; PLASMIDS; PROPIONATES; REACTIVE OXYGEN SPECIES; RNA, SMALL INTERFERING; S PHASE; SIGNAL TRANSDUCTION;

EID: 84873962597     PISSN: 0300483X     EISSN: 18793185     Source Type: Journal    
DOI: 10.1016/j.tox.2013.01.010     Document Type: Article

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