-
1
-
-
84867152637
-
Nonalcoholic fatty liver disease (NAFLD):is it really a serious condition?
-
Wattacheril J, Chalasani N. Nonalcoholic fatty liver disease (NAFLD):is it really a serious condition? Hepatology. 2012;56:1580-4.
-
(2012)
Hepatology
, vol.56
, pp. 1580-1584
-
-
Wattacheril, J.1
Chalasani, N.2
-
2
-
-
10644220306
-
Prevalence of hepatic steatosis in an urban population in the United States: impact of ethnicity
-
Browning JD, Szczepaniak LS, Dobbins R, Nuremberg P, Horton JD, Cohen JC, Grundy SM, Hobbs HH. Prevalence of hepatic steatosis in an urban population in the United States: impact of ethnicity. Hepatology. 2004;40:1387-95.
-
(2004)
Hepatology
, vol.40
, pp. 1387-1395
-
-
Browning, J.D.1
Szczepaniak, L.S.2
Dobbins, R.3
Nuremberg, P.4
Horton, J.D.5
Cohen, J.C.6
Grundy, S.M.7
Hobbs, H.H.8
-
3
-
-
25844500757
-
Predictors of nonalcoholic steatohepatitis (NASH) in obese patients undergoing gastric bypass
-
Boza C, Riquelme A, Ibanez L, Duarte I, Norero E, Viviani P, Soza A, Fernandez JI, Raddatz A, Guzman S, et al. Predictors of nonalcoholic steatohepatitis (NASH) in obese patients undergoing gastric bypass. Obes Surg. 2005;15:1148-53.
-
(2005)
Obes Surg
, vol.15
, pp. 1148-1153
-
-
Boza, C.1
Riquelme, A.2
Ibanez, L.3
Duarte, I.4
Norero, E.5
Viviani, P.6
Soza, A.7
Fernandez, J.I.8
Raddatz, A.9
Guzman, S.10
-
4
-
-
33748110788
-
Hepatic histology in obese patients undergoing bariatric surgery
-
Machado M, Marques-Vidal P, Cortez-Pinto H. Hepatic histology in obese patients undergoing bariatric surgery. J Hepatol. 2006;45:600-6.
-
(2006)
J Hepatol
, vol.45
, pp. 600-606
-
-
Machado, M.1
Marques-Vidal, P.2
Cortez-Pinto, H.3
-
5
-
-
33846473612
-
Nonalcoholic fatty liver disease in severely obese subjects
-
Gholam PM, Flancbaum L, Machan JT, Charney DA, Kotler DP. Nonalcoholic fatty liver disease in severely obese subjects. Am J Gastroenterol. 2007;102:399-408.
-
(2007)
Am J Gastroenterol
, vol.102
, pp. 399-408
-
-
Gholam, P.M.1
Flancbaum, L.2
Machan, J.T.3
Charney, D.A.4
Kotler, D.P.5
-
6
-
-
79960029926
-
Systematic review: the epidemiology and natural history of non-alcoholic fatty liver disease and nonalcoholic steatohepatitis in adults
-
Vernon G, Baranova A, Younossi ZM. Systematic review: the epidemiology and natural history of non-alcoholic fatty liver disease and nonalcoholic steatohepatitis in adults. Aliment Pharmacol Ther. 2011;34:274-85.
-
(2011)
Aliment Pharmacol Ther
, vol.34
, pp. 274-285
-
-
Vernon, G.1
Baranova, A.2
Younossi, Z.M.3
-
7
-
-
57749183469
-
Prevalence and associated factors of non-alcoholic fatty liver disease in patients with type-2 diabetes mellitus
-
Leite NC, Salles GF, Araujo ALE, Villela-Nogueira CA, Cardoso CRL. Prevalence and associated factors of non-alcoholic fatty liver disease in patients with type-2 diabetes mellitus. Liver Int. 2009;29:113-9.
-
(2009)
Liver Int
, vol.29
, pp. 113-119
-
-
Leite, N.C.1
Salles, G.F.2
Araujo, A.L.E.3
Villela-Nogueira, C.A.4
Cardoso, C.R.L.5
-
8
-
-
67650496665
-
Correlates and heritability of nonalcoholic fatty liver disease in a minority cohort
-
Wagenknecht LE, Scherzinger AL, Stamm ER, Hanley AJG, Norris JM, Chen YD, Bryer-Ash M, Haffner SM, Rotter JI. Correlates and heritability of nonalcoholic fatty liver disease in a minority cohort. Obesity (Silver Spring). 2009;17:1240-6.
-
(2009)
Obesity (Silver Spring)
, vol.17
, pp. 1240-1246
-
-
Wagenknecht, L.E.1
Scherzinger, A.L.2
Stamm, E.R.3
Hanley, A.J.G.4
Norris, J.M.5
Chen, Y.D.6
Bryer-Ash, M.7
Haffner, S.M.8
Rotter, J.I.9
-
9
-
-
48749130930
-
Relationship between alanine aminotransferase levels and metabolic syndrome in nonalcoholic fatty liver disease
-
Chen ZW, Chen L, Dai H, Chen J, Fang L. Relationship between alanine aminotransferase levels and metabolic syndrome in nonalcoholic fatty liver disease. J Zhejiang Univ Sci B. 2008;9:616-22.
-
(2008)
J Zhejiang Univ Sci B
, vol.9
, pp. 616-622
-
-
Chen, Z.W.1
Chen, L.2
Dai, H.3
Chen, J.4
Fang, L.5
-
10
-
-
0037382786
-
Nonalcoholic fatty liver, steatohepatitis, and the metabolic syndrome
-
Marchesini G, Bugianesi E, Forlani G, Cerrelli F, Lenzi M, Manini R, Natale S, Vanni E, Villanova N, Melchionda N, et al. Nonalcoholic fatty liver, steatohepatitis, and the metabolic syndrome. Hepatology. 2003;37:917-23.
-
(2003)
Hepatology
, vol.37
, pp. 917-923
-
-
Marchesini, G.1
Bugianesi, E.2
Forlani, G.3
Cerrelli, F.4
Lenzi, M.5
Manini, R.6
Natale, S.7
Vanni, E.8
Villanova, N.9
Melchionda, N.10
-
11
-
-
58849134985
-
Long-term follow-up of patients with nonalcoholic fatty liver
-
Rafiq N, Bai C, Fang Y, Srishord M, McCullough A, Gramlich T, Younossi ZM. Long-term follow-up of patients with nonalcoholic fatty liver. Clin Gastroenterol Hepatol. 2009;7:234-8.
-
(2009)
Clin Gastroenterol Hepatol
, vol.7
, pp. 234-238
-
-
Rafiq, N.1
Bai, C.2
Fang, Y.3
Srishord, M.4
McCullough, A.5
Gramlich, T.6
Younossi, Z.M.7
-
12
-
-
84863489710
-
Increased risk of cardiovascular disease and chronic kidney disease in NAFLD
-
Bonora E, Targher G. Increased risk of cardiovascular disease and chronic kidney disease in NAFLD. Nat Rev Gastroenterol Hepatol. 2012;9:372-81.
-
(2012)
Nat Rev Gastroenterol Hepatol
, vol.9
, pp. 372-381
-
-
Bonora, E.1
Targher, G.2
-
13
-
-
84861197159
-
Hepatocellular carcinoma in nonalcoholic fatty liver disease: an emerging menace
-
Baffy G, Brunt EM, Caldwell SH. Hepatocellular carcinoma in nonalcoholic fatty liver disease: an emerging menace. J Hepatol. 2012; 56:1384-91.
-
(2012)
J Hepatol
, vol.56
, pp. 1384-1391
-
-
Baffy, G.1
Brunt, E.M.2
Caldwell, S.H.3
-
14
-
-
84876683732
-
Anthropometric and clinical factors associated with mortality in subjects with nonalcoholic fatty liver disease
-
Otgonsuren M, Stepanova M, Gerber L, Younossi ZM. Anthropometric and clinical factors associated with mortality in subjects with nonalcoholic fatty liver disease. Dig Dis Sci. 2013;58:1132-40.
-
(2013)
Dig Dis Sci
, vol.58
, pp. 1132-1140
-
-
Otgonsuren, M.1
Stepanova, M.2
Gerber, L.3
Younossi, Z.M.4
-
15
-
-
84878930738
-
Progression of NAFLD to diabetes mellitus, cardiovascular disease or cirrhosis
-
Anstee QM, Targher G, Day CP. Progression of NAFLD to diabetes mellitus, cardiovascular disease or cirrhosis. Nat Rev Gastroenterol Hepatol. 2013;10:330-44.
-
(2013)
Nat Rev Gastroenterol Hepatol
, vol.10
, pp. 330-344
-
-
Anstee, Q.M.1
Targher, G.2
Day, C.P.3
-
16
-
-
84861591910
-
The diagnosis and management of nonalcoholic fatty liver disease: practice guideline by the American Gastroenterological Association, American Association for the Study of Liver Diseases, and American College of Gastroenterology
-
Chalasani N, Younossi Z, Lavine JE, Diehl AM, Brunt EM, Cusi K, Charlton M, Sanyal AJ. The diagnosis and management of nonalcoholic fatty liver disease: practice guideline by the American Gastroenterological Association, American Association for the Study of Liver Diseases, and American College of Gastroenterology. Gastroenterology. 2012;142:1592-609.
-
(2012)
Gastroenterology
, vol.142
, pp. 1592-1609
-
-
Chalasani, N.1
Younossi, Z.2
Lavine, J.E.3
Diehl, A.M.4
Brunt, E.M.5
Cusi, K.6
Charlton, M.7
Sanyal, A.J.8
-
18
-
-
6944252590
-
Invited review: pathology, etiology, prevention, and treatment of fatty liver in dairy cows
-
Bobe G, Young JW, Beitz DC. Invited review: pathology, etiology, prevention, and treatment of fatty liver in dairy cows. J Dairy Sci. 2004; 87:3105-24.
-
(2004)
J Dairy Sci
, vol.87
, pp. 3105-3124
-
-
Bobe, G.1
Young, J.W.2
Beitz, D.C.3
-
19
-
-
0030968879
-
Lipoprotein metabolism and fattening in poultry
-
Hermier D. Lipoprotein metabolism and fattening in poultry. J Nutr. 1997;127:S805-8.
-
(1997)
J Nutr
, vol.127
, pp. S805-S808
-
-
Hermier, D.1
-
20
-
-
0015394538
-
Uptake of individual free fatty acids by skeletal muscle and liver in man
-
Hagenfeldt L, Wahren J, Pernow B, Räf L. Uptake of individual free fatty acids by skeletal muscle and liver in man. J Clin Invest. 1972; 51:2324-30.
-
(1972)
J Clin Invest
, vol.51
, pp. 2324-2330
-
-
Hagenfeldt, L.1
Wahren, J.2
Pernow, B.3
Räf, L.4
-
21
-
-
78651140528
-
Uptake of plasma free fatty acids by the isolated rat liver: effect of glucagon
-
Aydin A, Sokal JE. Uptake of plasma free fatty acids by the isolated rat liver: effect of glucagon. Am J Physiol. 1963;205:667-70.
-
(1963)
Am J Physiol
, vol.205
, pp. 667-670
-
-
Aydin, A.1
Sokal, J.E.2
-
22
-
-
0038749401
-
Short communication: net uptake of nonesterified long chain fatty acids by the perfused caudate lobe of the caprine liver
-
Mashek DG, Grummer RR. Short communication: net uptake of nonesterified long chain fatty acids by the perfused caudate lobe of the caprine liver. J Dairy Sci. 2003;86:1218-20.
-
(2003)
J Dairy Sci
, vol.86
, pp. 1218-1220
-
-
Mashek, D.G.1
Grummer, R.R.2
-
23
-
-
78651127166
-
Factors affecting liver uptake of serum free stearic acid-1-C14
-
Trout DL, Estes EH Jr. Factors affecting liver uptake of serum free stearic acid-1-C14. Am J Physiol. 1962;203:1024-8.
-
(1962)
Am J Physiol
, vol.203
, pp. 1024-1028
-
-
Trout, D.L.1
Estes Jr., E.H.2
-
24
-
-
0016745095
-
The hepatic uptake of individual free fatty acids in sheep during noradrenaline infusion
-
Thompson GE, Darling KF. The hepatic uptake of individual free fatty acids in sheep during noradrenaline infusion. Res Vet Sci. 1975;18:325-7.
-
(1975)
Res Vet Sci
, vol.18
, pp. 325-327
-
-
Thompson, G.E.1
Darling, K.F.2
-
25
-
-
0029828647
-
Metabolic fate of oleic acid, palmitic acid and stearic acid in cultured hamster hepatocytes
-
Bruce JS, Salter AM. Metabolic fate of oleic acid, palmitic acid and stearic acid in cultured hamster hepatocytes. Biochem J. 1996;316:847-52.
-
(1996)
Biochem J
, vol.316
, pp. 847-852
-
-
Bruce, J.S.1
Salter, A.M.2
-
26
-
-
33646035836
-
Contributions of different fatty acid sources to very low-density lipoprotein-triacylglycerol in the fasted and fed states
-
Barrows BR, Parks EJ. Contributions of different fatty acid sources to very low-density lipoprotein-triacylglycerol in the fasted and fed states. J Clin Endocrinol Metab. 2006;91:1446-52.
-
(2006)
J Clin Endocrinol Metab
, vol.91
, pp. 1446-1452
-
-
Barrows, B.R.1
Parks, E.J.2
-
27
-
-
18244382304
-
Sources of fatty acids stored in liver and secreted via lipoproteins in patients with nonalcoholic fatty liver disease
-
Donnelly KL, Smith CI, Schwarzenberg SJ, Jessurun J, Boldt MD, Parks EJ. Sources of fatty acids stored in liver and secreted via lipoproteins in patients with nonalcoholic fatty liver disease. J Clin Invest. 2005; 115:1343-51.
-
(2005)
J Clin Invest
, vol.115
, pp. 1343-1351
-
-
Donnelly, K.L.1
Smith, C.I.2
Schwarzenberg, S.J.3
Jessurun, J.4
Boldt, M.D.5
Parks, E.J.6
-
28
-
-
30344441211
-
Relationship of hepatic steatosis to adipose tissue distribution in pediatric nonalcoholic fatty liver disease
-
Fishbein MH, Mogren C, Gleason T, Stevens WR. Relationship of hepatic steatosis to adipose tissue distribution in pediatric nonalcoholic fatty liver disease. J Pediatr Gastroenterol Nutr. 2006;42:83-8.
-
(2006)
J Pediatr Gastroenterol Nutr
, vol.42
, pp. 83-88
-
-
Fishbein, M.H.1
Mogren, C.2
Gleason, T.3
Stevens, W.R.4
-
29
-
-
33745401989
-
Visceral fat accumulation and insulin resistance are important factors in nonalcoholic fatty liver disease
-
Eguchi Y, Eguchi T, Mizuta T, Ide Y, Iwakiri R, Hisatomi A, Ozaki I, Yamamoto K, Kitajima Y, Kawaguchi Y, et al. Visceral fat accumulation and insulin resistance are important factors in nonalcoholic fatty liver disease. J Gastroenterol. 2006;41:462-9.
-
(2006)
J Gastroenterol
, vol.41
, pp. 462-469
-
-
Eguchi, Y.1
Eguchi, T.2
Mizuta, T.3
Ide, Y.4
Iwakiri, R.5
Hisatomi, A.6
Ozaki, I.7
Yamamoto, K.8
Kitajima, Y.9
Kawaguchi, Y.10
-
30
-
-
33947170005
-
Ultrasonographic and biochemical evaluation of visceral obesity in obese women with non-alcoholic fatty liver disease
-
Fenkci S, Rota S, Sabir N, Akdag B. Ultrasonographic and biochemical evaluation of visceral obesity in obese women with non-alcoholic fatty liver disease. Eur J Med Res. 2007;12:68-73.
-
(2007)
Eur J Med Res
, vol.12
, pp. 68-73
-
-
Fenkci, S.1
Rota, S.2
Sabir, N.3
Akdag, B.4
-
31
-
-
85047690933
-
Splanchnic lipolysis in human obesity
-
Nielsen S, Guo Z, Johnson CM, Hensrud DD, Jensen MD. Splanchnic lipolysis in human obesity. J Clin Invest. 2004;113:1582-8.
-
(2004)
J Clin Invest
, vol.113
, pp. 1582-1588
-
-
Nielsen, S.1
Guo, Z.2
Johnson, C.M.3
Hensrud, D.D.4
Jensen, M.D.5
-
32
-
-
24144470430
-
Spillover of dietary fatty acids and use of serum nonesterified fatty acids for the synthesis of VLDL-triacylglycerol under two different feeding regimens
-
Barrows BR, Timlin MT, Parks EJ. Spillover of dietary fatty acids and use of serum nonesterified fatty acids for the synthesis of VLDL-triacylglycerol under two different feeding regimens. Diabetes. 2005;54:2668-73.
-
(2005)
Diabetes
, vol.54
, pp. 2668-2673
-
-
Barrows, B.R.1
Timlin, M.T.2
Parks, E.J.3
-
33
-
-
33645994508
-
Targeted deletion of FATP5 reveals multiple functions in liver metabolism: alterations in hepatic lipid homeostasis
-
Doege H, Baiillie RA, Ortegon AM, Tsang B, Wu Q, Punreddy S, Hirsch D, Watson N, Gimeno RE, Stahl A. Targeted deletion of FATP5 reveals multiple functions in liver metabolism: alterations in hepatic lipid homeostasis. Gastroenterology. 2006;130:1245-58.
-
(2006)
Gastroenterology
, vol.130
, pp. 1245-1258
-
-
Doege, H.1
Baiillie, R.A.2
Ortegon, A.M.3
Tsang, B.4
Wu, Q.5
Punreddy, S.6
Hirsch, D.7
Watson, N.8
Gimeno, R.E.9
Stahl, A.10
-
34
-
-
77956803815
-
FATP2 is a hepatic fatty acid transporter and peroxisomal very long-chain acyl-CoA synthetase
-
Falcon A, Doege H, Fluitt A, Tsang B, Watson N, Kay MA, Stahl A. FATP2 is a hepatic fatty acid transporter and peroxisomal very long-chain acyl-CoA synthetase. Am J Physiol Endocrinol Metab. 2010;299:E384-93.
-
(2010)
Am J Physiol Endocrinol Metab
, vol.299
, pp. E384-E393
-
-
Falcon, A.1
Doege, H.2
Fluitt, A.3
Tsang, B.4
Watson, N.5
Kay, M.A.6
Stahl, A.7
-
35
-
-
36849037401
-
Increased hepatic CD36 expression contributes to dyslipidemia associated with diet-induced obesity
-
Koonen DPY, Jacobs RL, Febbraio M, Young ME, Soltys CLM, Ong H, Vance DE, Dyck JRB. Increased hepatic CD36 expression contributes to dyslipidemia associated with diet-induced obesity. Diabetes. 2007; 56:2863-71.
-
(2007)
Diabetes
, vol.56
, pp. 2863-2871
-
-
Koonen, D.P.Y.1
Jacobs, R.L.2
Febbraio, M.3
Young, M.E.4
Soltys, C.L.M.5
Ong, H.6
Vance, D.E.7
Dyck, J.R.B.8
-
36
-
-
45849118669
-
Gene expression in human NAFLD
-
Greco D, Kotronen A, Westerbacka J, Puig O, Arkkila P, Kivilouto T, Laitinen S, Kolak M, Fisher RM, Hamsten A, et al. Gene expression in human NAFLD. Am J Physiol Gastrointest Liver Physiol. 2008;294:G1281-7.
-
(2008)
Am J Physiol Gastrointest Liver Physiol
, vol.294
, pp. G1281-G1287
-
-
Greco, D.1
Kotronen, A.2
Westerbacka, J.3
Puig, O.4
Arkkila, P.5
Kivilouto, T.6
Laitinen, S.7
Kolak, M.8
Fisher, R.M.9
Hamsten, A.10
-
37
-
-
63649104470
-
Analysis of hepatic genes involved in the metabolism of fatty acids and iron in nonalcoholic fatty liver disease
-
Mitsuyoshi H, Yasui K, Harano Y, Endo M, Tsuji K, Minami M, Itoh Y, Okanoue T, Yoshikawa T. Analysis of hepatic genes involved in the metabolism of fatty acids and iron in nonalcoholic fatty liver disease. Hepatol Res. 2009;39:366-73.
-
(2009)
Hepatol Res
, vol.39
, pp. 366-373
-
-
Mitsuyoshi, H.1
Yasui, K.2
Harano, Y.3
Endo, M.4
Tsuji, K.5
Minami, M.6
Itoh, Y.7
Okanoue, T.8
Yoshikawa, T.9
-
38
-
-
0034693232
-
Defective uptake and utilization of long chain fatty acids in muscle and adipose tissues of CD36 knockout mice
-
Coburn CT, Knapp FF, Febbraio M, Beets AL, Silverstein RL, Abumrad NA. Defective uptake and utilization of long chain fatty acids in muscle and adipose tissues of CD36 knockout mice. J Biol Chem. 2000;275:32523-9.
-
(2000)
J Biol Chem
, vol.275
, pp. 32523-32529
-
-
Coburn, C.T.1
Knapp, F.F.2
Febbraio, M.3
Beets, A.L.4
Silverstein, R.L.5
Abumrad, N.A.6
-
39
-
-
2942711830
-
New concepts of cellular fatty acid uptake: role of fatty acid transport proteins and of caveolae
-
Pohl J, Ring A, Ehehalt R, Herrmann T, Stremmel W. New concepts of cellular fatty acid uptake: role of fatty acid transport proteins and of caveolae. Proc Nutr Soc. 2004;63:259-62.
-
(2004)
Proc Nutr Soc
, vol.63
, pp. 259-262
-
-
Pohl, J.1
Ring, A.2
Ehehalt, R.3
Herrmann, T.4
Stremmel, W.5
-
40
-
-
39849092042
-
Vectorial acylation: linking fatty acid transport and activation to metabolic trafficking
-
Black PN, DiRusso CC. Vectorial acylation: linking fatty acid transport and activation to metabolic trafficking. Novartis Found Symp. 2007; 286:127-38.
-
(2007)
Novartis Found Symp
, vol.286
, pp. 127-138
-
-
Black, P.N.1
DiRusso, C.C.2
-
41
-
-
33646862402
-
Cellular fatty acid uptake: the contribution of metabolism
-
Mashek DG, Coleman RA. Cellular fatty acid uptake: the contribution of metabolism. Curr Opin Lipidol. 2006;17:274-8.
-
(2006)
Curr Opin Lipidol
, vol.17
, pp. 274-278
-
-
Mashek, D.G.1
Coleman, R.A.2
-
42
-
-
27144465180
-
Membrane binding proteins are the major determinants for the hepatocellular transmembrane flux of long-chain fatty acids bound to albumin
-
Rajaraman G, Roberts MS, Hung D, Wang GQ, Burczynski FJ. Membrane binding proteins are the major determinants for the hepatocellular transmembrane flux of long-chain fatty acids bound to albumin. Pharm Res. 2005;22:1793-804.
-
(2005)
Pharm Res
, vol.22
, pp. 1793-1804
-
-
Rajaraman, G.1
Roberts, M.S.2
Hung, D.3
Wang, G.Q.4
Burczynski, F.J.5
-
43
-
-
0027077992
-
Characteristics of oleate binding to liver plasma membranes and its uptake by isolated hepatocytes
-
Stump DD, Nunes RM, Sorrentino D, Isola LM, Berk PD. Characteristics of oleate binding to liver plasma membranes and its uptake by isolated hepatocytes. J Hepatol. 1992;16:304-15.
-
(1992)
J Hepatol
, vol.16
, pp. 304-315
-
-
Stump, D.D.1
Nunes, R.M.2
Sorrentino, D.3
Isola, L.M.4
Berk, P.D.5
-
44
-
-
0025032691
-
Fatty acid-binding protein expression in the liver: its regulation and relationship to the zonation of fatty acid metabolism
-
Bass NM. Fatty acid-binding protein expression in the liver: its regulation and relationship to the zonation of fatty acid metabolism. Mol Cell Biochem. 1990;98:167-76.
-
(1990)
Mol Cell Biochem
, vol.98
, pp. 167-176
-
-
Bass, N.M.1
-
45
-
-
0347065337
-
Decreased hepatic triglyceride accumulation and altered fatty acid uptake in mice with deletion of the liver fatty acid-binding protein gene
-
Newberry EP, Xie Y, Kennedy S, Han X, Buhman KK, Luo J, Gross RW, Davidson NO. Decreased hepatic triglyceride accumulation and altered fatty acid uptake in mice with deletion of the liver fatty acid-binding protein gene. J Biol Chem. 2003;278:51664-72.
-
(2003)
J Biol Chem
, vol.278
, pp. 51664-51672
-
-
Newberry, E.P.1
Xie, Y.2
Kennedy, S.3
Han, X.4
Buhman, K.K.5
Luo, J.6
Gross, R.W.7
Davidson, N.O.8
-
46
-
-
0032960138
-
Role of acylCoA binding protein in acylCoA transport, metabolism and cell signaling
-
Knudsen J, Jensen MV, Hansen JK, Faergeman NJ, Neergaard TB, Gaigg B. Role of acylCoA binding protein in acylCoA transport, metabolism and cell signaling. Mol Cell Biochem. 1999;192:95-103
-
(1999)
Mol Cell Biochem
, vol.192
, pp. 95-103
-
-
Knudsen, J.1
Jensen, M.V.2
Hansen, J.K.3
Faergeman, N.J.4
Neergaard, T.B.5
Gaigg, B.6
-
47
-
-
0014107415
-
Lipogenesis in the pigeon: in vivo studies
-
Goodridge AG, Ball EG. Lipogenesis in the pigeon: in vivo studies. Am J Physiol. 1967;213:245-9.
-
(1967)
Am J Physiol
, vol.213
, pp. 245-249
-
-
Goodridge, A.G.1
Ball, E.G.2
-
48
-
-
0017394702
-
Influence of dietary lipid on lipogenic enzyme activities in coho salmon, Oncorhynchus kisutch (Walbaum)
-
Lin H, Romsos DR, Tack PI, Leveille GA. Influence of dietary lipid on lipogenic enzyme activities in coho salmon, Oncorhynchus kisutch (Walbaum). J Nutr. 1977;107:846-54.
-
(1977)
J Nutr
, vol.107
, pp. 846-854
-
-
Lin, H.1
Romsos, D.R.2
Tack, P.I.3
Leveille, G.A.4
-
49
-
-
0014971569
-
Comparative aspects of lipogenesis in mammalian tissues
-
Shrago E, Glennon JA, Gordon ES. Comparative aspects of lipogenesis in mammalian tissues. Metabolism. 1971;20:54-62.
-
(1971)
Metabolism
, vol.20
, pp. 54-62
-
-
Shrago, E.1
Glennon, J.A.2
Gordon, E.S.3
-
50
-
-
0014439798
-
Gluconeogenesis and lipogenesis in tissue from ruminant and nonruminant animals
-
Ballard FJ, Hanson RW, Kronfeld DS. Gluconeogenesis and lipogenesis in tissue from ruminant and nonruminant animals. Fed Proc. 1969;28:218-31.
-
(1969)
Fed Proc
, vol.28
, pp. 218-231
-
-
Ballard, F.J.1
Hanson, R.W.2
Kronfeld, D.S.3
-
51
-
-
0014604558
-
Significance of adipose tissue and liver as sites of fatty acid synthesis in the pig and the efficiency of utilization of various substrates for lipogenesis
-
O'Hea EK, Leveille GA. Significance of adipose tissue and liver as sites of fatty acid synthesis in the pig and the efficiency of utilization of various substrates for lipogenesis. J Nutr. 1969;99:338-44.
-
(1969)
J Nutr
, vol.99
, pp. 338-344
-
-
O'Hea, E.K.1
Leveille, G.A.2
-
53
-
-
13744263104
-
Temporal pattern of de novo lipogenesis in the postprandial state in healthy men
-
Timlin MT, Parks EJ. Temporal pattern of de novo lipogenesis in the postprandial state in healthy men. Am J Clin Nutr. 2005;81:35-42.
-
(2005)
Am J Clin Nutr
, vol.81
, pp. 35-42
-
-
Timlin, M.T.1
Parks, E.J.2
-
55
-
-
72649089588
-
Acute or chronic upregulation of mitochondrial fatty acid oxidation has no net effect on whole-body energy expenditure or adiposity
-
Hoehn KL, Turner N, Swarbrick MW, Wilks D, Preston E, Phua Y, Joshi H, Furler SM, Larance M, Hegarty BD, et al. Acute or chronic upregulation of mitochondrial fatty acid oxidation has no net effect on whole-body energy expenditure or adiposity. Cell Metab. 2010; 11:70-6.
-
(2010)
Cell Metab
, vol.11
, pp. 70-76
-
-
Hoehn, K.L.1
Turner, N.2
Swarbrick, M.W.3
Wilks, D.4
Preston, E.5
Phua, Y.6
Joshi, H.7
Furler, S.M.8
Larance, M.9
Hegarty, B.D.10
-
56
-
-
0035970805
-
Continuous fatty acid oxidation and reduced fat storage in mice lacking acetyl-CoA carboxylase 2
-
Abu-Elheiga L, Matzuk MM, Abo-Hashema KA,Wakil SJ. Continuous fatty acid oxidation and reduced fat storage in mice lacking acetyl-CoA carboxylase 2. Science. 2001;291:2613-6.
-
(2001)
Science
, vol.291
, pp. 2613-2616
-
-
Abu-Elheiga, L.1
Matzuk, M.M.2
Abo-Hashema, K.A.3
Wakil, S.J.4
-
57
-
-
33847232207
-
Hepatic de novo lipogenesis is present in liver-specific ACC1-deficient mice
-
Harada N, Oda Z, Hara Y, Fujinami K, Okawa M, Ohbuchi K, Yonemoto M, Ikeda Y, Ohwaki K, Aragane K, et al. Hepatic de novo lipogenesis is present in liver-specific ACC1-deficient mice. Mol Cell Biol. 2007;27:1881-8.
-
(2007)
Mol Cell Biol
, vol.27
, pp. 1881-1888
-
-
Harada, N.1
Oda, Z.2
Hara, Y.3
Fujinami, K.4
Okawa, M.5
Ohbuchi, K.6
Yonemoto, M.7
Ikeda, Y.8
Ohwaki, K.9
Aragane, K.10
-
58
-
-
0031839599
-
Hepatic secretion of VLDL fatty acids during stimulated lipogenesis in men
-
Aarsland A, Wolfe RR. Hepatic secretion of VLDL fatty acids during stimulated lipogenesis in men. J Lipid Res. 1998;39:1280-6.
-
(1998)
J Lipid Res
, vol.39
, pp. 1280-1286
-
-
Aarsland, A.1
Wolfe, R.R.2
-
59
-
-
67650088283
-
Biochemical and physiological function of stearoyl-CoA desaturase
-
Paton CM, Ntambi JM. Biochemical and physiological function of stearoyl-CoA desaturase. Am J Physiol Endocrinol Metab. 2009;297:E28-37.
-
(2009)
Am J Physiol Endocrinol Metab
, vol.297
, pp. E28-E37
-
-
Paton, C.M.1
Ntambi, J.M.2
-
60
-
-
77953515738
-
Role of fatty acid elongases in determination of de novo synthesized monounsaturated fatty acid species
-
Green CD, Ozguden-Akkoc CG, Wang Y, Jump DB, Olson LK. Role of fatty acid elongases in determination of de novo synthesized monounsaturated fatty acid species. J Lipid Res. 2010;51:1871-7.
-
(2010)
J Lipid Res
, vol.51
, pp. 1871-1877
-
-
Green, C.D.1
Ozguden-Akkoc, C.G.2
Wang, Y.3
Jump, D.B.4
Olson, L.K.5
-
61
-
-
78149284997
-
Role of hepatic desaturases in obesity-related metabolic disorders
-
Bjermo H, Risérus U. Role of hepatic desaturases in obesity-related metabolic disorders. Curr Opin Clin Nutr Metab Care. 2010;13:703-8.
-
(2010)
Curr Opin Clin Nutr Metab Care
, vol.13
, pp. 703-708
-
-
Bjermo, H.1
Risérus, U.2
-
62
-
-
74949099984
-
Mammalian fatty acid elongases
-
Jump DB. Mammalian fatty acid elongases. Methods Mol Biol. 2009; 579:375-89.
-
(2009)
Methods Mol Biol
, vol.579
, pp. 375-389
-
-
Jump, D.B.1
-
63
-
-
71049158067
-
Suppression of long chain acyl-CoA synthetase 3 decreases hepatic de novo fatty acid synthesis through decreased transcriptional activity
-
Bu SY, Mashek MT, Mashek DG. Suppression of long chain acyl-CoA synthetase 3 decreases hepatic de novo fatty acid synthesis through decreased transcriptional activity. J Biol Chem. 2009;284:30474-83.
-
(2009)
J Biol Chem
, vol.284
, pp. 30474-30483
-
-
Bu, S.Y.1
Mashek, M.T.2
Mashek, D.G.3
-
64
-
-
78149314978
-
Hepatic long-chain acyl-CoA synthetase 5 mediates fatty acid channeling between anabolic and catabolic pathways
-
Bu SY, Mashek DG. Hepatic long-chain acyl-CoA synthetase 5 mediates fatty acid channeling between anabolic and catabolic pathways. J Lipid Res. 2010;51:3270-80.
-
(2010)
J Lipid Res
, vol.51
, pp. 3270-3280
-
-
Bu, S.Y.1
Mashek, D.G.2
-
65
-
-
80054057662
-
Mammalian triacylglycerol metabolism:synthesis, lipolysis, and signaling
-
Coleman RA, Mashek DG. Mammalian triacylglycerol metabolism:synthesis, lipolysis, and signaling. Chem Rev. 2011;111:6359-86.
-
(2011)
Chem Rev
, vol.111
, pp. 6359-6386
-
-
Coleman, R.A.1
Mashek, D.G.2
-
66
-
-
0015502065
-
A substrate-and position-specific acylation of sn-glycerol 3-phosphate by rat liver mitochondria
-
Monroy G, Rola FH, Pullman ME. A substrate-and position-specific acylation of sn-glycerol 3-phosphate by rat liver mitochondria. J Biol Chem. 1972;247:6884-94.
-
(1972)
J Biol Chem
, vol.247
, pp. 6884-6894
-
-
Monroy, G.1
Rola, F.H.2
Pullman, M.E.3
-
67
-
-
0031552990
-
Mammalian mitochondrial glycerol-3-phosphate acyltransferase
-
Dircks LK, Sul HS. Mammalian mitochondrial glycerol-3-phosphate acyltransferase. Biochim Biophys Acta. 1997;1348:17-26.
-
(1997)
Biochim Biophys Acta
, vol.1348
, pp. 17-26
-
-
Dircks, L.K.1
Sul, H.S.2
-
68
-
-
84884562454
-
Glycerol-3-phosphate acyltransferase (GPAT)-1, but not GPAT4, incorporates newly synthesized fatty acids into triacylglycerol and diminishes fatty acid oxidation
-
Epub, Aug 1
-
Wendel AA, Cooper DE, Ilkayeva OR, Muoio DM, Coleman RA. Glycerol-3-phosphate acyltransferase (GPAT)-1, but not GPAT4, incorporates newly synthesized fatty acids into triacylglycerol and diminishes fatty acid oxidation. J Biol Chem. Epub 2013 Aug 1.
-
(2013)
J Biol Chem
-
-
Wendel, A.A.1
Cooper, D.E.2
Ilkayeva, O.R.3
Muoio, D.M.4
Coleman, R.A.5
-
69
-
-
84861425644
-
The use of stable isotope-labeled glycerol and oleic acid to differentiate the hepatic functions of DGAT1 and -2
-
Qi J, Lang W, Geisler JG, Wang P, Petrounia I, Mai S, Smith C, Askari H, Struble GT,Williams R, et al. The use of stable isotope-labeled glycerol and oleic acid to differentiate the hepatic functions of DGAT1 and -2. J Lipid Res. 2012;53:1106-16.
-
(2012)
J Lipid Res
, vol.53
, pp. 1106-1116
-
-
Qi, J.1
Lang, W.2
Geisler, J.G.3
Wang, P.4
Petrounia, I.5
Mai, S.6
Smith, C.7
Askari, H.8
Struble, G.T.9
Williams, R.10
-
70
-
-
84865227832
-
Diacylglycerol acyltransferase 2 (DGAT2) acts upstream of DGAT1, and utilises nascent diglycerides and de novo synthesised fatty acids in HepG2 cells
-
Wurie HR, Buckett L, Zammit VA. Diacylglycerol acyltransferase 2 (DGAT2) acts upstream of DGAT1, and utilises nascent diglycerides and de novo synthesised fatty acids in HepG2 cells. FEBS J. 2012; 279:3033-47.
-
(2012)
FEBS J
, vol.279
, pp. 3033-3047
-
-
Wurie, H.R.1
Buckett, L.2
Zammit, V.A.3
-
71
-
-
68949181550
-
Specific role for acyl CoA:Diacylglycerol acyltransferase 1 (Dgat1) in hepatic steatosis due to exogenous fatty acids
-
Villanueva CJ, Monetti M, Shih M, Zhou P, Watkins SM, Bhanot S, Farese RV. Specific role for acyl CoA:Diacylglycerol acyltransferase 1 (Dgat1) in hepatic steatosis due to exogenous fatty acids. Hepatology. 2009;50:434-42.
-
(2009)
Hepatology
, vol.50
, pp. 434-442
-
-
Villanueva, C.J.1
Monetti, M.2
Shih, M.3
Zhou, P.4
Watkins, S.M.5
Bhanot, S.6
Farese, R.V.7
-
72
-
-
84860280975
-
Evidence for regulated monoacylglycerol acyltransferase expression and activity in human liver
-
Hall AM, Kou K, Chen Z, Pietka TA, Kumar M, Korenblat KM, Lee K, Ahn K, Fabbrini E, Klein S, et al. Evidence for regulated monoacylglycerol acyltransferase expression and activity in human liver. J Lipid Res. 2012;53:990-9.
-
(2012)
J Lipid Res
, vol.53
, pp. 990-999
-
-
Hall, A.M.1
Kou, K.2
Chen, Z.3
Pietka, T.A.4
Kumar, M.5
Korenblat, K.M.6
Lee, K.7
Ahn, K.8
Fabbrini, E.9
Klein, S.10
-
73
-
-
33644861799
-
Rat long chain acyl-CoA synthetase 5 increases fatty acid uptake and partitioning to cellular triacylglycerol in McArdle-RH7777 cells
-
Mashek DG, McKenzie MA, Van Horn CG, Coleman RA. Rat long chain acyl-CoA synthetase 5 increases fatty acid uptake and partitioning to cellular triacylglycerol in McArdle-RH7777 cells. J Biol Chem. 2006;281:945-50.
-
(2006)
J Biol Chem
, vol.281
, pp. 945-950
-
-
Mashek, D.G.1
McKenzie, M.A.2
Van Horn, C.G.3
Coleman, R.A.4
-
74
-
-
56749096610
-
Genetic variation in PNPLA3 confers susceptibility to nonalcoholic fatty liver disease
-
Romeo S, Kozlitina J, Zing C, Petsemlidis A, Cox D, Pennacchio LA, Boerwinkle E, Cohen JC, Hobbs HH. Genetic variation in PNPLA3 confers susceptibility to nonalcoholic fatty liver disease. Nat Genet. 2008;40:1461-5.
-
(2008)
Nat Genet
, vol.40
, pp. 1461-1465
-
-
Romeo, S.1
Kozlitina, J.2
Zing, C.3
Petsemlidis, A.4
Cox, D.5
Pennacchio, L.A.6
Boerwinkle, E.7
Cohen, J.C.8
Hobbs, H.H.9
-
75
-
-
78650064129
-
Effects of PNPLA3 on liver fat and metabolic profile in Hispanic children and adolescents
-
Goran MI, Walker R, Le KA, Mahurka S, Vikman S, Davis JN, Spruijt-Metz D, Weigensberg MJ, Allayee H. Effects of PNPLA3 on liver fat and metabolic profile in Hispanic children and adolescents. Diabetes. 2010;59:3127-30.
-
(2010)
Diabetes
, vol.59
, pp. 3127-3130
-
-
Goran, M.I.1
Walker, R.2
Le, K.A.3
Mahurka, S.4
Vikman, S.5
Davis, J.N.6
Spruijt-Metz, D.7
Weigensberg, M.J.8
Allayee, H.9
-
76
-
-
77949895032
-
A sequence variation (I148M) in PNPLA3 associated with nonalcoholic fatty liver disease disrupts triglyceride hydrolysis
-
He S, McPhaul C, Li JZ, Garuti R, Kinch L, Grishin NV, Cohen JC, Hobbs HH. A sequence variation (I148M) in PNPLA3 associated with nonalcoholic fatty liver disease disrupts triglyceride hydrolysis. J Biol Chem. 2010;285:6706-15.
-
(2010)
J Biol Chem
, vol.285
, pp. 6706-6715
-
-
He, S.1
McPhaul, C.2
Li, J.Z.3
Garuti, R.4
Kinch, L.5
Grishin, N.V.6
Cohen, J.C.7
Hobbs, H.H.8
-
77
-
-
78751489992
-
Pnpla3/Adiponutrin deficiency in mice does not contribute to fatty liver disease or metabolic syndrome
-
Basantani MK, Sitnick MT, Cai L, Brenner DS, Gardner NP, Li JZ, Schoiswohl G, Yang K, Kumari M, Gross RW, et al. Pnpla3/Adiponutrin deficiency in mice does not contribute to fatty liver disease or metabolic syndrome. J Lipid Res. 2011;52:318-29.
-
(2011)
J Lipid Res
, vol.52
, pp. 318-329
-
-
Basantani, M.K.1
Sitnick, M.T.2
Cai, L.3
Brenner, D.S.4
Gardner, N.P.5
Li, J.Z.6
Schoiswohl, G.7
Yang, K.8
Kumari, M.9
Gross, R.W.10
-
78
-
-
77956625538
-
Patatin-like phospholipase domaincontaining 3/adiponutrin deficiency in mice is not associated with fatty liver disease
-
Chen W, Chang B, Li L, Chan L. Patatin-like phospholipase domaincontaining 3/adiponutrin deficiency in mice is not associated with fatty liver disease. Hepatology. 2010;52:1134-42.
-
(2010)
Hepatology
, vol.52
, pp. 1134-1142
-
-
Chen, W.1
Chang, B.2
Li, L.3
Chan, L.4
-
79
-
-
84860465005
-
Adiponutrin functions as a nutritionally regulated lysophosphatidic acid acyltransferase
-
Kumari M, Schoiswohl G, Chitraju C, Paar M, Cornaciu I, Rangrez AY, Wongsiriroj N, Nagy HM, Ivanova PT, Scott SA, et al. Adiponutrin functions as a nutritionally regulated lysophosphatidic acid acyltransferase. Cell Metab. 2012;15:691-702.
-
(2012)
Cell Metab
, vol.15
, pp. 691-702
-
-
Kumari, M.1
Schoiswohl, G.2
Chitraju, C.3
Paar, M.4
Cornaciu, I.5
Rangrez, A.Y.6
Wongsiriroj, N.7
Nagy, H.M.8
Ivanova, P.T.9
Scott, S.A.10
-
80
-
-
84872492049
-
Molecular mechanisms and the role of saturated fatty acids in the progression of non-alcoholic fatty liver disease
-
Leamy AK, Egnatchik RA, Young JD. Molecular mechanisms and the role of saturated fatty acids in the progression of non-alcoholic fatty liver disease. Prog Lipid Res. 2013;52:165-74.
-
(2013)
Prog Lipid Res
, vol.52
, pp. 165-174
-
-
Leamy, A.K.1
Egnatchik, R.A.2
Young, J.D.3
-
81
-
-
34347235098
-
Dissociation of hepatic steatosis and insulin resistance in mice overexpressing DGAT in the liver
-
Monetti M, Levin MC, Watt MJ, Sajan MP, Marmor S, Hubbard BK, Stevens RD, Bain JR, Newgard CB, Farese RV, et al. Dissociation of hepatic steatosis and insulin resistance in mice overexpressing DGAT in the liver. Cell Metab. 2007;6:69-78.
-
(2007)
Cell Metab
, vol.6
, pp. 69-78
-
-
Monetti, M.1
Levin, M.C.2
Watt, M.J.3
Sajan, M.P.4
Marmor, S.5
Hubbard, B.K.6
Stevens, R.D.7
Bain, J.R.8
Newgard, C.B.9
Farese, R.V.10
-
82
-
-
34250356015
-
Inhibiting triglyceride synthesis improves hepatic steatosis but exacerbates liver damage and fibrosis in obese mice with nonalcoholic steatohepatitis
-
Yamaguchi K, Yang L, McCall S, Huang J, Yu XX, Pandey SK, Bhanot S, Monia BP, Li YX, Diehl AM. Inhibiting triglyceride synthesis improves hepatic steatosis but exacerbates liver damage and fibrosis in obese mice with nonalcoholic steatohepatitis. Hepatology. 2007;45:1366-74.
-
(2007)
Hepatology
, vol.45
, pp. 1366-1374
-
-
Yamaguchi, K.1
Yang, L.2
McCall, S.3
Huang, J.4
Yu, X.X.5
Pandey, S.K.6
Bhanot, S.7
Monia, B.P.8
Li, Y.X.9
Diehl, A.M.10
-
83
-
-
66349088529
-
Hepatic triacylglycerol accumulation and insulin resistance
-
Nagle CA, Klett EL, Coleman RA. Hepatic triacylglycerol accumulation and insulin resistance. J Lipid Res. 2009;50:S74-9.
-
(2009)
J Lipid Res
, vol.50
, pp. S74-S79
-
-
Nagle, C.A.1
Klett, E.L.2
Coleman, R.A.3
-
84
-
-
84863115883
-
Glycerolipid signals alter mTOR complex 2 (mTORC2) to diminish insulin signaling
-
Zhang C, Wendel AA, Keogh MR, Harris TE, Chen J, Coleman RA. Glycerolipid signals alter mTOR complex 2 (mTORC2) to diminish insulin signaling. Proc Natl Acad Sci USA. 2012;109:1667-72.
-
(2012)
Proc Natl Acad Sci USA
, vol.109
, pp. 1667-1672
-
-
Zhang, C.1
Wendel, A.A.2
Keogh, M.R.3
Harris, T.E.4
Chen, J.5
Coleman, R.A.6
-
85
-
-
0037453056
-
Triglyceride accumulation protects against fatty acidinduced lipotoxicity
-
Listenberger LL, Han X, Lewis SE, Cases S, Farese RV, Ory DS, Schaffer JE. Triglyceride accumulation protects against fatty acidinduced lipotoxicity. Proc Natl Acad Sci U S A. 2003;100:3077-82.
-
(2003)
Proc Natl Acad Sci U S A
, vol.100
, pp. 3077-3082
-
-
Listenberger, L.L.1
Han, X.2
Lewis, S.E.3
Cases, S.4
Farese, R.V.5
Ory, D.S.6
Schaffer, J.E.7
-
86
-
-
84875326507
-
Triacylglycerol synthesis enzymes mediate lipid droplet growth by relocalizing from the ER to lipid droplets
-
Wilfling F, Wang H, Haas JT, Krahmer N, Gould TJ, Uchida A, Cheng JX, Graham M, Christiano R, Frohlich F, et al. Triacylglycerol synthesis enzymes mediate lipid droplet growth by relocalizing from the ER to lipid droplets. Dev Cell. 2013;24:384-99.
-
(2013)
Dev Cell
, vol.24
, pp. 384-399
-
-
Wilfling, F.1
Wang, H.2
Haas, J.T.3
Krahmer, N.4
Gould, T.J.5
Uchida, A.6
Cheng, J.X.7
Graham, M.8
Christiano, R.9
Frohlich, F.10
-
87
-
-
84856072854
-
Packaging of fat: an evolving model of lipid droplet assembly and expansion
-
Brasaemle DL,Wolins NE. Packaging of fat: an evolving model of lipid droplet assembly and expansion. J Biol Chem. 2012;287:2273-9.
-
(2012)
J Biol Chem
, vol.287
, pp. 2273-2279
-
-
Brasaemle, D.L.1
Wolins, N.E.2
-
88
-
-
77950350763
-
Expression of perilipin and adipophilin in nonalcoholic fatty liver disease; relevance to oxidative injury and hepatocyte ballooning
-
Fujii H, Ikura Y, Arimoto J, Sugioka K, Iezzoni JC, Park SH, Naruko T, Itabe H, Kawada N, Caldwell SH, et al. Expression of perilipin and adipophilin in nonalcoholic fatty liver disease; relevance to oxidative injury and hepatocyte ballooning. J Atheroscler Thromb. 2009;16:893-901.
-
(2009)
J Atheroscler Thromb
, vol.16
, pp. 893-901
-
-
Fujii, H.1
Ikura, Y.2
Arimoto, J.3
Sugioka, K.4
Iezzoni, J.C.5
Park, S.H.6
Naruko, T.7
Itabe, H.8
Kawada, N.9
Caldwell, S.H.10
-
89
-
-
46249097997
-
Differential pattern of lipid droplet-associated proteins and de novo perilipin expression in hepatocyte steatogenesis
-
Straub BK, Stoeffel P, Heid H, Zimbelmann R, Schirmacher P. Differential pattern of lipid droplet-associated proteins and de novo perilipin expression in hepatocyte steatogenesis. Hepatology. 2008;47:1936-46.
-
(2008)
Hepatology
, vol.47
, pp. 1936-1946
-
-
Straub, B.K.1
Stoeffel, P.2
Heid, H.3
Zimbelmann, R.4
Schirmacher, P.5
-
91
-
-
0015497517
-
Caloric homeostasis and disorders of fuel transport
-
Havel RJ. Caloric homeostasis and disorders of fuel transport. N Engl J Med. 1972;287:1186-92.
-
(1972)
N Engl J Med
, vol.287
, pp. 1186-1192
-
-
Havel, R.J.1
-
92
-
-
77956629388
-
Adipose acyl-CoA synthetase-1 directs fatty acids toward beta-oxidation and is required for cold thermogenesis
-
Ellis JM, Li LO, Wu PC, Koves TR, Ilkayeva O, Stevens RD, Watkins SM, Muoio DM, Coleman RA. Adipose acyl-CoA synthetase-1 directs fatty acids toward beta-oxidation and is required for cold thermogenesis. Cell Metab. 2010;12:53-64.
-
(2010)
Cell Metab
, vol.12
, pp. 53-64
-
-
Ellis, J.M.1
Li, L.O.2
Wu, P.C.3
Koves, T.R.4
Ilkayeva, O.5
Stevens, R.D.6
Watkins, S.M.7
Muoio, D.M.8
Coleman, R.A.9
-
93
-
-
79952267150
-
Mouse cardiac acyl coenzyme a synthetase 1 deficiency impairs fatty acid oxidation and induces cardiac hypertrophy
-
Ellis JM, Mentock SM, Depetrillo MA, Koves TR, Sen S, Watkins SM, Muoio DM, Cline GW, Taegtmeyer H, Shulman GI, et al. Mouse cardiac acyl coenzyme a synthetase 1 deficiency impairs fatty acid oxidation and induces cardiac hypertrophy. Mol Cell Biol. 2011;31:1252-62.
-
(2011)
Mol Cell Biol
, vol.31
, pp. 1252-1262
-
-
Ellis, J.M.1
Mentock, S.M.2
Depetrillo, M.A.3
Koves, T.R.4
Sen, S.5
Watkins, S.M.6
Muoio, D.M.7
Cline, G.W.8
Taegtmeyer, H.9
Shulman, G.I.10
-
94
-
-
70350450243
-
Liver-specific loss of long chain acyl-CoA synthetase-1 decreases triacylglycerol synthesis and beta-oxidation and alters phospholipid fatty acid composition
-
Li LO, Ellis JM, Paich HA,Wang S, Gong N, Altshuller G, Thresher RJ, Koves TR, Watkins SM, Muoio DM, et al. Liver-specific loss of long chain acyl-CoA synthetase-1 decreases triacylglycerol synthesis and beta-oxidation and alters phospholipid fatty acid composition. J Biol Chem. 2009;284:27816-26.
-
(2009)
J Biol Chem
, vol.284
, pp. 27816-27826
-
-
Li, L.O.1
Ellis, J.M.2
Paich, H.A.3
Wang, S.4
Gong, N.5
Altshuller, G.6
Thresher, R.J.7
Koves, T.R.8
Watkins, S.M.9
Muoio, D.M.10
-
95
-
-
1442314719
-
Liver fatty acid binding protein is required for high rates of hepatic fatty acid oxidation but not for the action of PPARalpha in fasting mice
-
Erol E, Kumar LS, Cline GW, Shulman GI, Kelly DP, Binas B. Liver fatty acid binding protein is required for high rates of hepatic fatty acid oxidation but not for the action of PPARalpha in fasting mice. FASEB J. 2004;18:347-9.
-
(2004)
FASEB J
, vol.18
, pp. 347-349
-
-
Erol, E.1
Kumar, L.S.2
Cline, G.W.3
Shulman, G.I.4
Kelly, D.P.5
Binas, B.6
-
96
-
-
0024503108
-
Compartmentation of hepatic fatty-acid-binding protein in liver cells and its effect on microsomal phosphatidic acid biosynthesis
-
Bordewick U, Heese M, Borchers T, Robenek H, Spener F. Compartmentation of hepatic fatty-acid-binding protein in liver cells and its effect on microsomal phosphatidic acid biosynthesis. Biol Chem Hoppe Seyler. 1989;370:229-38.
-
(1989)
Biol Chem Hoppe Seyler
, vol.370
, pp. 229-238
-
-
Bordewick, U.1
Heese, M.2
Borchers, T.3
Robenek, H.4
Spener, F.5
-
97
-
-
77958154359
-
Liver fatty acid-binding protein and obesity
-
Atshaves BP, Martin GG, Hostetler HA, McIntosh AL, Kier AB, Schroeder F. Liver fatty acid-binding protein and obesity. J Nutr Biochem. 2010;21:1015-32.
-
(2010)
J Nutr Biochem
, vol.21
, pp. 1015-1032
-
-
Atshaves, B.P.1
Martin, G.G.2
Hostetler, H.A.3
McIntosh, A.L.4
Kier, A.B.5
Schroeder, F.6
-
98
-
-
0022346123
-
Substrate inhibition of carnitine palmitoyltransferase by palmitoyl-CoA and activation by phospholipids and proteins
-
Woldegiorgis G, Bremer J, Shrago E. Substrate inhibition of carnitine palmitoyltransferase by palmitoyl-CoA and activation by phospholipids and proteins. Biochim Biophys Acta. 1985;837:135-40.
-
(1985)
Biochim Biophys Acta
, vol.837
, pp. 135-140
-
-
Woldegiorgis, G.1
Bremer, J.2
Shrago, E.3
-
99
-
-
0017738601
-
A possible role for malonyl-CoA in the regulation of hepatic fatty acid oxidation and ketogenesis
-
McGarry JD, Mannaerts GP, Foster DW. A possible role for malonyl-CoA in the regulation of hepatic fatty acid oxidation and ketogenesis. J Clin Invest. 1977;60:265-70.
-
(1977)
J Clin Invest
, vol.60
, pp. 265-270
-
-
McGarry, J.D.1
Mannaerts, G.P.2
Foster, D.W.3
-
100
-
-
50549202600
-
The glucose fattyacid cycle. Its role in insulin sensitivity and the metabolic disturbances of diabetes mellitus
-
Randle PJ, Garland PB, Hales CN, Newsholme EA. The glucose fattyacid cycle. Its role in insulin sensitivity and the metabolic disturbances of diabetes mellitus. Lancet. 1963;1:785-9.
-
(1963)
Lancet
, vol.1
, pp. 785-789
-
-
Randle, P.J.1
Garland, P.B.2
Hales, C.N.3
Newsholme, E.A.4
-
101
-
-
66949149506
-
Modulation of the hepatic malonyl-CoA-carnitine palmitoyltransferase 1A partnership creates a metabolic switch allowing oxidation of de novo fatty acids
-
Akkaoui M, Cohen I, Esnous C, Lenoir V, Sournac M, Girard J, Prip-Buss C. Modulation of the hepatic malonyl-CoA-carnitine palmitoyltransferase 1A partnership creates a metabolic switch allowing oxidation of de novo fatty acids. Biochem J. 2009;420:429-38.
-
(2009)
Biochem J
, vol.420
, pp. 429-438
-
-
Akkaoui, M.1
Cohen, I.2
Esnous, C.3
Lenoir, V.4
Sournac, M.5
Girard, J.6
Prip-Buss, C.7
-
102
-
-
45549089456
-
A moderate increase in carnitine palmitoyltransferase 1a activity is sufficient to substantially reduce hepatic triglyceride levels
-
Stefanovic-Racic M, Perdomo G, Mantell BS, Sipula IJ, Brown NF, O'Doherty RM. A moderate increase in carnitine palmitoyltransferase 1a activity is sufficient to substantially reduce hepatic triglyceride levels. Am J Physiol Endocrinol Metab. 2008;294:E969-77.
-
(2008)
Am J Physiol Endocrinol Metab
, vol.294
, pp. E969-E977
-
-
Stefanovic-Racic, M.1
Perdomo, G.2
Mantell, B.S.3
Sipula, I.J.4
Brown, N.F.5
O'Doherty, R.M.6
-
103
-
-
79952211574
-
Molecular therapy for obesity and diabetes based on a longterm increase in hepatic fatty-acid oxidation
-
Orellana-Gavaldà JM, Herrero L, Malandrino MI, Paneda A, Sol Rodrizuez-Pena M, Petry H, Asins G, Van Deventer S, Hegardt FG, Serra D. Molecular therapy for obesity and diabetes based on a longterm increase in hepatic fatty-acid oxidation. Hepatology. 2011;53:821-32.
-
(2011)
Hepatology
, vol.53
, pp. 821-832
-
-
Orellana-Gavaldà, J.M.1
Herrero, L.2
Malandrino, M.I.3
Paneda, A.4
Sol Rodrizuez-Pena, M.5
Petry, H.6
Asins, G.7
van Deventer, S.8
Hegardt, F.G.9
Serra, D.10
-
104
-
-
33645820583
-
Liver-directed overexpression of mitochondrial glycerol-3-phosphate acyltransferase results in hepatic steatosis, increased triacylglycerol secretion and reduced fatty acid oxidation
-
Lindén D, William-Olsson L, Ahnmark A, Ekroos K, Hallberg C, Sjogren HP, Becker B, Svensson L, Clapham JC, Oscarsson J, et al. Liver-directed overexpression of mitochondrial glycerol-3-phosphate acyltransferase results in hepatic steatosis, increased triacylglycerol secretion and reduced fatty acid oxidation. FASEB J. 2006;20:434-43.
-
(2006)
FASEB J
, vol.20
, pp. 434-443
-
-
Lindén, D.1
William-Olsson, L.2
Ahnmark, A.3
Ekroos, K.4
Hallberg, C.5
Sjogren, H.P.6
Becker, B.7
Svensson, L.8
Clapham, J.C.9
Oscarsson, J.10
-
105
-
-
41149157330
-
The role of mitochondrial glycerol-3-phosphate acyltransferase-1 in regulating lipid and glucose homeostasis in high-fat diet fed mice
-
Yazdi M, Ahnmark A, William-Olsson L, Snaith M, Turner N, Osla F, Wedin M, Asztely AK, Elmgren A, Bohlooly-Y M, et al. The role of mitochondrial glycerol-3-phosphate acyltransferase-1 in regulating lipid and glucose homeostasis in high-fat diet fed mice. Biochem Biophys Res Commun. 2008;369:1065-70.
-
(2008)
Biochem Biophys Res Commun
, vol.369
, pp. 1065-1070
-
-
Yazdi, M.1
Ahnmark, A.2
William-Olsson, L.3
Snaith, M.4
Turner, N.5
Osla, F.6
Wedin, M.7
Asztely, A.K.8
Elmgren, A.9
Bohlooly-Y, M.10
-
106
-
-
23044450772
-
Antisense oligonucleotide reduction of DGAT2 expression improves hepatic steatosis and hyperlipidemia in obese mice
-
Yu XX, Murray SF, Pandey SK, Booten SL, Bao D, Song XZ, Kelly S, Chen S, McKay R, Monia BP, et al. Antisense oligonucleotide reduction of DGAT2 expression improves hepatic steatosis and hyperlipidemia in obese mice. Hepatology. 2005;42:362-71.
-
(2005)
Hepatology
, vol.42
, pp. 362-371
-
-
Yu, X.X.1
Murray, S.F.2
Pandey, S.K.3
Booten, S.L.4
Bao, D.5
Song, X.Z.6
Kelly, S.7
Chen, S.8
McKay, R.9
Monia, B.P.10
-
107
-
-
34547946930
-
Suppression of diacylglycerol acyltransferase-2 (DGAT2), but not DGAT1, with antisense oligonucleotides reverses diet-induced hepatic steatosis and insulin resistance
-
Choi CS, Savage DB, Kulkarni A, Yu XX, Liu ZX, Morino K, Kim S, Distefano A, Samuel VT, Neschen S, et al. Suppression of diacylglycerol acyltransferase-2 (DGAT2), but not DGAT1, with antisense oligonucleotides reverses diet-induced hepatic steatosis and insulin resistance. J Biol Chem. 2007;282:22678-88.
-
(2007)
J Biol Chem
, vol.282
, pp. 22678-22688
-
-
Choi, C.S.1
Savage, D.B.2
Kulkarni, A.3
Yu, X.X.4
Liu, Z.X.5
Morino, K.6
Kim, S.7
Distefano, A.8
Samuel, V.T.9
Neschen, S.10
-
108
-
-
78751496304
-
Adipose triglyceride lipase is a major hepatic lipase that regulates triacylglycerol turnover and fatty acid signaling and partitioning
-
Ong KT, Mashek MT, Bu SY, Greenberg AS, Mashek DG. Adipose triglyceride lipase is a major hepatic lipase that regulates triacylglycerol turnover and fatty acid signaling and partitioning. Hepatology. 2011; 53:116-26.
-
(2011)
Hepatology
, vol.53
, pp. 116-126
-
-
Ong, K.T.1
Mashek, M.T.2
Bu, S.Y.3
Greenberg, A.S.4
Mashek, D.G.5
-
109
-
-
79959550724
-
Deficiency of liver adipose triglyceride lipase in mice causes progressive hepatic steatosis
-
Wu JW, Wang SP, Alvarez F, Casavant S, Gauthier N, Abed L, Soni KG, Yang G, Mitchell GA. Deficiency of liver adipose triglyceride lipase in mice causes progressive hepatic steatosis. Hepatology. 2011; 54:122-32.
-
(2011)
Hepatology
, vol.54
, pp. 122-132
-
-
Wu, J.W.1
Wang, S.P.2
Alvarez, F.3
Casavant, S.4
Gauthier, N.5
Abed, L.6
Soni, K.G.7
Yang, G.8
Mitchell, G.A.9
-
110
-
-
69449087522
-
Hepatic triacylglycerol hydrolysis regulates peroxisome proliferator-activated receptor alpha activity
-
Sapiro JM, Mashek MT, Greenberg AS, Mashek DG. Hepatic triacylglycerol hydrolysis regulates peroxisome proliferator-activated receptor alpha activity. J Lipid Res. 2009;50:1621-9.
-
(2009)
J Lipid Res
, vol.50
, pp. 1621-1629
-
-
Sapiro, J.M.1
Mashek, M.T.2
Greenberg, A.S.3
Mashek, D.G.4
-
111
-
-
84881263523
-
Deficiency of liver Comparative Gene Identification-58 causes steatohepatitis and fibrosis in mice
-
Guo F, Ma Y, Kadegowda AKG, Xie P, Liu G, Liu X, Miao H, Ou J, Su X, Zheng Z, et al. Deficiency of liver Comparative Gene Identification-58 causes steatohepatitis and fibrosis in mice. J Lipid Res. 2013; 54:2109-20.
-
(2013)
J Lipid Res
, vol.54
, pp. 2109-2120
-
-
Guo, F.1
Ma, Y.2
Kadegowda, A.K.G.3
Xie, P.4
Liu, G.5
Liu, X.6
Miao, H.7
Ou, J.8
Su, X.9
Zheng, Z.10
-
112
-
-
78149346457
-
CGI-58 knockdown in mice causes hepatic steatosis but prevents diet-induced obesity and glucose intolerance
-
Brown JM, Betters JL, Lord C, Ma Y, Han X, Yang K, Alger HM, Melchior J, Sawyer J, Shah R, et al. CGI-58 knockdown in mice causes hepatic steatosis but prevents diet-induced obesity and glucose intolerance. J Lipid Res. 2010;51:3306-15.
-
(2010)
J Lipid Res
, vol.51
, pp. 3306-3315
-
-
Brown, J.M.1
Betters, J.L.2
Lord, C.3
Ma, Y.4
Han, X.5
Yang, K.6
Alger, H.M.7
Melchior, J.8
Sawyer, J.9
Shah, R.10
-
113
-
-
0035958917
-
The triple threat to nascent apolipoprotein B. Evidence for multiple, distinct degradative pathways
-
Fisher EA, Pan M, Xhen X, Wu X, Wang H, Jamil H, Sparks JD, Williams KJ. The triple threat to nascent apolipoprotein B. Evidence for multiple, distinct degradative pathways. J Biol Chem. 2001;276:27855-63.
-
(2001)
J Biol Chem
, vol.276
, pp. 27855-27863
-
-
Fisher, E.A.1
Pan, M.2
Xhen, X.3
Wu, X.4
Wang, H.5
Jamil, H.6
Sparks, J.D.7
Williams, K.J.8
-
114
-
-
0027504998
-
Proteolysis and lipidfacilitated translocation are distinct but competitive processes that regulate secretion of apolipoprotein B in Hep G2 cells
-
Sakata N, Wu X, Dixon JL, Ginsberg HN. Proteolysis and lipidfacilitated translocation are distinct but competitive processes that regulate secretion of apolipoprotein B in Hep G2 cells. J Biol Chem. 1993;268:22967-70.
-
(1993)
J Biol Chem
, vol.268
, pp. 22967-22970
-
-
Sakata, N.1
Wu, X.2
Dixon, J.L.3
Ginsberg, H.N.4
-
115
-
-
0030725291
-
Intracellular degradation of newly synthesized apolipoprotein B
-
Yao Z, Tran K, McLeod RS. Intracellular degradation of newly synthesized apolipoprotein B. J Lipid Res. 1997;38:1937-53.
-
(1997)
J Lipid Res
, vol.38
, pp. 1937-1953
-
-
Yao, Z.1
Tran, K.2
McLeod, R.S.3
-
116
-
-
0032927776
-
Apolipoprotein B in the rough endoplasmic reticulum: translation, translocation and the initiation of lipoprotein assembly
-
Shelness GS, Ingram MF, Huang XF, DeLozier JA. Apolipoprotein B in the rough endoplasmic reticulum: translation, translocation and the initiation of lipoprotein assembly. J Nutr. 1999;129:S456-62.
-
(1999)
J Nutr
, vol.129
, pp. S456-S462
-
-
Shelness, G.S.1
Ingram, M.F.2
Huang, X.F.3
DeLozier, J.A.4
-
117
-
-
0344349000
-
Analysis of the role of microsomal triglyceride transfer protein in the liver of tissue-specific knockout mice
-
Raabe M, Veniant MM, Sullivan MA, Zlot CH, Bjorkegren J, Nielsen LB, Wong JS, Hamilton RL, Young SG. Analysis of the role of microsomal triglyceride transfer protein in the liver of tissue-specific knockout mice. J Clin Invest. 1999;103:1287-98.
-
(1999)
J Clin Invest
, vol.103
, pp. 1287-1298
-
-
Raabe, M.1
Veniant, M.M.2
Sullivan, M.A.3
Zlot, C.H.4
Bjorkegren, J.5
Nielsen, L.B.6
Wong, J.S.7
Hamilton, R.L.8
Young, S.G.9
-
118
-
-
0037040195
-
The late addition of core lipids to nascent apolipoprotein B100, resulting in the assembly and secretion of triglyceride-rich lipoproteins, is independent of both microsomal triglyceride transfer protein activity and new triglyceride synthesis
-
Pan M, Liang Js J, Fisher EA, Ginsberg HN. The late addition of core lipids to nascent apolipoprotein B100, resulting in the assembly and secretion of triglyceride-rich lipoproteins, is independent of both microsomal triglyceride transfer protein activity and new triglyceride synthesis. J Biol Chem. 2002;277:4413-21.
-
(2002)
J Biol Chem
, vol.277
, pp. 4413-4421
-
-
Pan, M.1
Liang Js, J.2
Fisher, E.A.3
Ginsberg, H.N.4
-
119
-
-
0028821066
-
Origin of triacylglycerol moiety of plasma very low density lipoproteins in the rat: structural studies
-
Yang LY, Kuksis A, Myher JJ, Steiner G. Origin of triacylglycerol moiety of plasma very low density lipoproteins in the rat: structural studies. J Lipid Res. 1995;36:125-36.
-
(1995)
J Lipid Res
, vol.36
, pp. 125-136
-
-
Yang, L.Y.1
Kuksis, A.2
Myher, J.J.3
Steiner, G.4
-
120
-
-
0029892064
-
Contribution of de novo fatty acid synthesis to very low density lipoprotein triacylglycerols: evidence from mass isotopomer distribution analysis of fatty acids synthesized from [2H6]ethanol
-
Yang LY, Kuksis A, Myher JJ, Steiner G. Contribution of de novo fatty acid synthesis to very low density lipoprotein triacylglycerols: evidence from mass isotopomer distribution analysis of fatty acids synthesized from [2H6]ethanol. J Lipid Res. 1996;37:262-74.
-
(1996)
J Lipid Res
, vol.37
, pp. 262-274
-
-
Yang, L.Y.1
Kuksis, A.2
Myher, J.J.3
Steiner, G.4
-
121
-
-
0031711606
-
Use of cytosolic triacylglycerol hydrolysis products and of exogenous fatty acid for the synthesis of triacylglycerol secreted by cultured rat hepatocytes
-
Lankester DL, Brown AM, Zammit VA. Use of cytosolic triacylglycerol hydrolysis products and of exogenous fatty acid for the synthesis of triacylglycerol secreted by cultured rat hepatocytes. J Lipid Res. 1998;39:1889-95.
-
(1998)
J Lipid Res
, vol.39
, pp. 1889-1895
-
-
Lankester, D.L.1
Brown, A.M.2
Zammit, V.A.3
-
122
-
-
77249149984
-
Loss of TGH/Ces3 in mice decreases blood lipids, improves glucose tolerance, and increases energy expenditure
-
Wei E, Wen Ali Y, Lyon J, Wang H, Nelson R, Dolinsky VW, Dyck JR, Mitchell G, Korbutt GS, Lehner R. Loss of TGH/Ces3 in mice decreases blood lipids, improves glucose tolerance, and increases energy expenditure. Cell Metab. 2010;11:183-93.
-
(2010)
Cell Metab
, vol.11
, pp. 183-193
-
-
Wei, E.1
Wen Ali, Y.2
Lyon, J.3
Wang, H.4
Nelson, R.5
Dolinsky, V.W.6
Dyck, J.R.7
Mitchell, G.8
Korbutt, G.S.9
Lehner, R.10
-
123
-
-
84867023428
-
Liver specific inactivation of carboxylesterase 3/Triacylglycerol hydrolase decreases blood lipids without causing severe steatosis
-
Lian J, Wei E, Wang SP, Quiroga AD, Li L, Pardo AD, van der Veen J, Sipione S, Mitchell GA, Lehner R. Liver specific inactivation of carboxylesterase 3/Triacylglycerol hydrolase decreases blood lipids without causing severe steatosis. Hepatology. 2012;56:2154-62.
-
(2012)
Hepatology
, vol.56
, pp. 2154-2162
-
-
Lian, J.1
Wei, E.2
Wang, S.P.3
Quiroga, A.D.4
Li, L.5
Pardo, A.D.6
van der Veen, J.7
Sipione, S.8
Mitchell, G.A.9
Lehner, R.10
-
124
-
-
77953523654
-
Altered lipid droplet dynamics in hepatocytes lacking triacylglycerol hydrolase expression
-
Wang H, Wei E, Quiroga AD, Sun X, Touret N, Lehner R. Altered lipid droplet dynamics in hepatocytes lacking triacylglycerol hydrolase expression. Mol Biol Cell. 2010;21:1991-2000.
-
(2010)
Mol Biol Cell
, vol.21
, pp. 1991-2000
-
-
Wang, H.1
Wei, E.2
Quiroga, A.D.3
Sun, X.4
Touret, N.5
Lehner, R.6
-
125
-
-
12844286809
-
Triacylglycerol hydrolase is localized to the endoplasmic reticulum by an unusual retrieval sequence where it participates in VLDL assembly without utilizing VLDL lipids as substrates
-
Gilham D, Alam M, Gao W, Vance DE, Lehner R. Triacylglycerol hydrolase is localized to the endoplasmic reticulum by an unusual retrieval sequence where it participates in VLDL assembly without utilizing VLDL lipids as substrates. Mol Biol Cell. 2005;16:984-96.
-
(2005)
Mol Biol Cell
, vol.16
, pp. 984-996
-
-
Gilham, D.1
Alam, M.2
Gao, W.3
Vance, D.E.4
Lehner, R.5
-
126
-
-
84868701222
-
Deficiency of carboxylesterase 1/esterase-x results in obesity, hepatic steatosis, and hyperlipidemia
-
Quiroga AD, Li L, Trötzmüller M, Nelson R, Proctor SD, Köfeler H, Lehner R. Deficiency of carboxylesterase 1/esterase-x results in obesity, hepatic steatosis, and hyperlipidemia. Hepatology. 2012; 56:2188-98.
-
(2012)
Hepatology
, vol.56
, pp. 2188-2198
-
-
Quiroga, A.D.1
Li, L.2
Trötzmüller, M.3
Nelson, R.4
Proctor, S.D.5
Köfeler, H.6
Lehner, R.7
-
127
-
-
84856731141
-
A role for seipin in lipid droplet dynamics and inheritance in yeast
-
Wolinski H, Kolb D, Hermann S, Koning RI, Kohlwein SD. A role for seipin in lipid droplet dynamics and inheritance in yeast. J Cell Sci. 2011;124:3894-904.
-
(2011)
J Cell Sci
, vol.124
, pp. 3894-3904
-
-
Wolinski, H.1
Kolb, D.2
Hermann, S.3
Koning, R.I.4
Kohlwein, S.D.5
-
128
-
-
58749098423
-
Cideb, an ERand lipid droplet-associated protein, mediates VLDL lipidation and maturation by interacting with apolipoprotein B
-
Ye J, Li JZ, Liu Y, Li X, Yang T, Ma X, Li Q, Yao Z, Li P. Cideb, an ERand lipid droplet-associated protein, mediates VLDL lipidation and maturation by interacting with apolipoprotein B. Cell Metab. 2009; 9:177-90.
-
(2009)
Cell Metab
, vol.9
, pp. 177-190
-
-
Ye, J.1
Li, J.Z.2
Liu, Y.3
Li, X.4
Yang, T.5
Ma, X.6
Li, Q.7
Yao, Z.8
Li, P.9
-
129
-
-
84864862383
-
Opposing roles of cell deathinducing DFF45-like effector B and perilipin 2 in controlling hepatic VLDL lipidation
-
Li X, Ye J, Zhou L, Gu W, Fisher EA, Li P. Opposing roles of cell deathinducing DFF45-like effector B and perilipin 2 in controlling hepatic VLDL lipidation. J Lipid Res. 2012;53:1877-89.
-
(2012)
J Lipid Res
, vol.53
, pp. 1877-1889
-
-
Li, X.1
Ye, J.2
Zhou, L.3
Gu, W.4
Fisher, E.A.5
Li, P.6
-
130
-
-
7244242391
-
Overexpression of human diacylglycerol acyltransferase 1, acyl-coa:cholesterol acyltransferase 1, or acyl-CoA:cholesterol acyltransferase 2 stimulates secretion of apolipoprotein B-containing lipoproteins in McA-RH7777 cells
-
Liang JJ, Oelkers P, Guo C, Chu P-C, Dixon JL, Ginsberg HN, Sturley SL. Overexpression of human diacylglycerol acyltransferase 1, acyl-coa:cholesterol acyltransferase 1, or acyl-CoA:cholesterol acyltransferase 2 stimulates secretion of apolipoprotein B-containing lipoproteins in McA-RH7777 cells. J Biol Chem. 2004;279:44938-44.
-
(2004)
J Biol Chem
, vol.279
, pp. 44938-44944
-
-
Liang, J.J.1
Oelkers, P.2
Guo, C.3
Chu, P.-C.4
Dixon, J.L.5
Ginsberg, H.N.6
Sturley, S.L.7
-
131
-
-
0036737798
-
Distinct ontogenic patterns of overt and latent DGAT activities of rat liver microsomes
-
Waterman IJ, Price NT, Zammit VA. Distinct ontogenic patterns of overt and latent DGAT activities of rat liver microsomes. J Lipid Res. 2002;43:1555-62.
-
(2002)
J Lipid Res
, vol.43
, pp. 1555-1562
-
-
Waterman, I.J.1
Price, N.T.2
Zammit, V.A.3
-
132
-
-
33845587374
-
Delayed secretory pathway contributions to VLDL-triglycerides from plasma NEFA, diet, and de novo lipogenesis in humans
-
Vedala A, Wang W, Neese RA, Christiansen MP, Hellerstein MK. Delayed secretory pathway contributions to VLDL-triglycerides from plasma NEFA, diet, and de novo lipogenesis in humans. J Lipid Res. 2006;47:2562-74.
-
(2006)
J Lipid Res
, vol.47
, pp. 2562-2574
-
-
Vedala, A.1
Wang, W.2
Neese, R.A.3
Christiansen, M.P.4
Hellerstein, M.K.5
-
133
-
-
0025427649
-
A species comparison of liver slice synthesis and secretion of triacylglycerol from nonesterified fatty acids in media
-
Pullen DL, Liesman JS, Emery RS. A species comparison of liver slice synthesis and secretion of triacylglycerol from nonesterified fatty acids in media. J Anim Sci. 1990;68:1395-9.
-
(1990)
J Anim Sci
, vol.68
, pp. 1395-1399
-
-
Pullen, D.L.1
Liesman, J.S.2
Emery, R.S.3
-
134
-
-
0033619738
-
Evaluation of the affinity and turnover number of both hepatic mitochondrial and microsomal carnitine acyltransferases: relevance to intracellular partitioning of acyl-CoAs
-
Abo-Hashema KA, Cake MH, Lukas MA, Knudsen J. Evaluation of the affinity and turnover number of both hepatic mitochondrial and microsomal carnitine acyltransferases: relevance to intracellular partitioning of acyl-CoAs. Biochemistry. 1999;38:15840-7.
-
(1999)
Biochemistry
, vol.38
, pp. 15840-15847
-
-
Abo-Hashema, K.A.1
Cake, M.H.2
Lukas, M.A.3
Knudsen, J.4
-
135
-
-
0029156130
-
Inhibition of liver microsomal carnitine acyltransferases by sulphonylurea drugs
-
Broadway NM, Saggerson ED. Inhibition of liver microsomal carnitine acyltransferases by sulphonylurea drugs. FEBS Lett. 1995;371:137-9.
-
(1995)
FEBS Lett
, vol.371
, pp. 137-139
-
-
Broadway, N.M.1
Saggerson, E.D.2
-
136
-
-
65949095803
-
Autophagy regulates lipid metabolism
-
Singh R, Kaushik S, Wang Y, Xiang Y, Novak I, Komatsu M, Tanaka K, Cuervo AM, Czaja MJ. Autophagy regulates lipid metabolism. Nature. 2009;458:1131-5.
-
(2009)
Nature
, vol.458
, pp. 1131-1135
-
-
Singh, R.1
Kaushik, S.2
Wang, Y.3
Xiang, Y.4
Novak, I.5
Komatsu, M.6
Tanaka, K.7
Cuervo, A.M.8
Czaja, M.J.9
-
137
-
-
84864947432
-
Autophagy-lysosomal pathway is involved in lipid degradation in rat liver
-
Skop V, Cahová M, Papáčková Z, Páleníčková E, Daňková H, Baranowski M, Zabielski P, Zdychová J, Zídková J, Kazdová L. Autophagy-lysosomal pathway is involved in lipid degradation in rat liver. Physiol Res. 2012;61:287-97.
-
(2012)
Physiol Res
, vol.61
, pp. 287-297
-
-
Skop, V.1
Cahová, M.2
Papáčková, Z.3
Páleníčková, E.4
Daňková, H.5
Baranowski, M.6
Zabielski, P.7
Zdychová, J.8
Zídková, J.9
Kazdová, L.10
-
138
-
-
1542283630
-
Peroxisome proliferator-activated receptor alpha target genes
-
Mandard S, Müller M, Kersten S. Peroxisome proliferator-activated receptor alpha target genes. Cell Mol Life Sci. 2004;61:393-416.
-
(2004)
Cell Mol Life Sci
, vol.61
, pp. 393-416
-
-
Mandard, S.1
Müller, M.2
Kersten, S.3
-
139
-
-
0141592581
-
Unsaturated fatty acid regulation of peroxisome proliferator-activated receptor alpha activity in rat primary hepatocytes
-
Pawar A, Jump DB. Unsaturated fatty acid regulation of peroxisome proliferator-activated receptor alpha activity in rat primary hepatocytes. J Biol Chem. 2003;278:35931-9.
-
(2003)
J Biol Chem
, vol.278
, pp. 35931-35939
-
-
Pawar, A.1
Jump, D.B.2
-
140
-
-
68149098866
-
Identification of a physiologically relevant endogenous ligand for PPARalpha in liver
-
Chakravarthy MV, Lodhi IJ, Yin L, Malapaka RR, Xu HE, Turk J, Semenkovich CF. Identification of a physiologically relevant endogenous ligand for PPARalpha in liver. Cell. 2009;138:476-88.
-
(2009)
Cell
, vol.138
, pp. 476-488
-
-
Chakravarthy, M.V.1
Lodhi, I.J.2
Yin, L.3
Malapaka, R.R.4
Xu, H.E.5
Turk, J.6
Semenkovich, C.F.7
-
141
-
-
79953210362
-
Regulation of PGC-1a, a nodal regulator of mitochondrial biogenesis
-
Fernandez-Marcos PJ, Auwerx J. Regulation of PGC-1a, a nodal regulator of mitochondrial biogenesis. Am J Clin Nutr. 2011;93:S884-90.
-
(2011)
Am J Clin Nutr
, vol.93
, pp. S884-S890
-
-
Fernandez-Marcos, P.J.1
Auwerx, J.2
-
142
-
-
67649403606
-
FoxO1 controls insulin-dependent adipose triglyceride lipase (ATGL) expression and lipolysis in adipocytes
-
Chakrabarti P, Kandror KV. FoxO1 controls insulin-dependent adipose triglyceride lipase (ATGL) expression and lipolysis in adipocytes. J Biol Chem. 2009;284:13296-300.
-
(2009)
J Biol Chem
, vol.284
, pp. 13296-13300
-
-
Chakrabarti, P.1
Kandror, K.V.2
-
143
-
-
80053450975
-
The emerging roles of fatty acid translocase/CD36 and the aryl hydrocarbon receptor in fatty liver disease
-
He J, Lee JH, Febbraio M, Xie W. The emerging roles of fatty acid translocase/CD36 and the aryl hydrocarbon receptor in fatty liver disease. Exp Biol Med. 2011;236:1116-21.
-
(2011)
Exp Biol Med
, vol.236
, pp. 1116-1121
-
-
He, J.1
Lee, J.H.2
Febbraio, M.3
Xie, W.4
-
144
-
-
84855430898
-
Foxa1 reduces lipid accumulation in human hepatocytes and is down-regulated in nonalcoholic fatty liver
-
Moya M, Benet M, Guzmán C, Tolosa L, García-Monzón C, Pareja E, Castell JV, Jover R. Foxa1 reduces lipid accumulation in human hepatocytes and is down-regulated in nonalcoholic fatty liver. PLoS ONE. 2012;7:e30014.
-
(2012)
PLoS ONE
, vol.7
-
-
Moya, M.1
Benet, M.2
Guzmán, C.3
Tolosa, L.4
García-Monzón, C.5
Pareja, E.6
Castell, J.V.7
Jover, R.8
-
145
-
-
75149177340
-
Hepatocyte nuclear factor 4alpha coordinates a transcription factor network regulating hepatic fatty acid metabolism
-
Martinez-Jimenez CP, Kyrmizi I, Cardot P, Gonzalez FJ, Talianidis I. Hepatocyte nuclear factor 4alpha coordinates a transcription factor network regulating hepatic fatty acid metabolism. Mol Cell Biol. 2010;30:565-77.
-
(2010)
Mol Cell Biol
, vol.30
, pp. 565-577
-
-
Martinez-Jimenez, C.P.1
Kyrmizi, I.2
Cardot, P.3
Gonzalez, F.J.4
Talianidis, I.5
-
146
-
-
79551483835
-
Hepatic hepatocyte nuclear factor 4a is essential for maintaining triglyceride and cholesterol homeostasis
-
Yin L, Ma H, Ge X, Edwards PA, Zhang Y. Hepatic hepatocyte nuclear factor 4a is essential for maintaining triglyceride and cholesterol homeostasis. Arterioscler Thromb Vasc Biol. 2011;31:328-36.
-
(2011)
Arterioscler Thromb Vasc Biol
, vol.31
, pp. 328-336
-
-
Yin, L.1
Ma, H.2
Ge, X.3
Edwards, P.A.4
Zhang, Y.5
-
147
-
-
11144244418
-
Foxa2 regulates lipid metabolism and ketogenesis in the liver during fasting and in diabetes
-
Wolfrum C, Asilmaz E, Luca E, Friedman JM, Stoffel M. Foxa2 regulates lipid metabolism and ketogenesis in the liver during fasting and in diabetes. Nature. 2004;432:1027-32.
-
(2004)
Nature
, vol.432
, pp. 1027-1032
-
-
Wolfrum, C.1
Asilmaz, E.2
Luca, E.3
Friedman, J.M.4
Stoffel, M.5
-
148
-
-
32444451567
-
Coactivation of Foxa2 through Pgc-1beta promotes liver fatty acid oxidation and triglyceride/VLDL secretion
-
Wolfrum C, Stoffel M. Coactivation of Foxa2 through Pgc-1beta promotes liver fatty acid oxidation and triglyceride/VLDL secretion. Cell Metab. 2006;3:99-110.
-
(2006)
Cell Metab
, vol.3
, pp. 99-110
-
-
Wolfrum, C.1
Stoffel, M.2
-
149
-
-
0031963963
-
Nutritional and insulin regulation of fatty acid synthetase and leptin gene expression through ADD1/SREBP1
-
Kim JB, Sarraf P, Wright M, Yao KM, Mueller E, Solanes G, Lowell BB, Spiegelman BM. Nutritional and insulin regulation of fatty acid synthetase and leptin gene expression through ADD1/SREBP1. J Clin Invest. 1998;101:1-9.
-
(1998)
J Clin Invest
, vol.101
, pp. 1-9
-
-
Kim, J.B.1
Sarraf, P.2
Wright, M.3
Yao, K.M.4
Mueller, E.5
Solanes, G.6
Lowell, B.B.7
Spiegelman, B.M.8
-
150
-
-
1842375053
-
Upstream stimulatory factor binding to the E-box at -65 is required for insulin regulation of the fatty acid synthase promoter
-
Wang D, Sul HS. Upstream stimulatory factor binding to the E-box at -65 is required for insulin regulation of the fatty acid synthase promoter. J Biol Chem. 1997;272:26367-74.
-
(1997)
J Biol Chem
, vol.272
, pp. 26367-26374
-
-
Wang, D.1
Sul, H.S.2
-
151
-
-
77957302090
-
Hepatic steatosis: a role for de novo lipogenesis and the transcription factor SREBP-1c
-
Ferré P, Foufelle F. Hepatic steatosis: a role for de novo lipogenesis and the transcription factor SREBP-1c. Diabetes Obes Metab. 2010; 12:83-92.
-
(2010)
Diabetes Obes Metab
, vol.12
, pp. 83-92
-
-
Ferré, P.1
Foufelle, F.2
-
152
-
-
45849137877
-
Regulation of hepatic lipogenesis by the transcription factor XBP1
-
Lee A-H, Scapa EF, Cohen DE, Glimcher LH. Regulation of hepatic lipogenesis by the transcription factor XBP1. Science. 2008;320:1492-6.
-
(2008)
Science
, vol.320
, pp. 1492-1496
-
-
Lee, A.-H.1
Scapa, E.F.2
Cohen, D.E.3
Glimcher, L.H.4
-
153
-
-
33749407193
-
ChREBP*Mlx is the principal mediator of glucose-induced gene expression in the liver
-
Ma L, Robinson LN, Towle HC. ChREBP*Mlx is the principal mediator of glucose-induced gene expression in the liver. J Biol Chem. 2006;281:28721-30.
-
(2006)
J Biol Chem
, vol.281
, pp. 28721-28730
-
-
Ma, L.1
Robinson, L.N.2
Towle, H.C.3
-
154
-
-
0035979214
-
A glucose-responsive transcription factor that regulates carbohydrate metabolism in the liver
-
Yamashita H, Takenoshita M, Sakurai M, Bruick RK, Henzel WJ, Shillinglaw W, Arnot D, Uyeda K. A glucose-responsive transcription factor that regulates carbohydrate metabolism in the liver. Proc Natl Acad Sci USA. 2001;98:9116-21.
-
(2001)
Proc Natl Acad Sci USA
, vol.98
, pp. 9116-9121
-
-
Yamashita, H.1
Takenoshita, M.2
Sakurai, M.3
Bruick, R.K.4
Henzel, W.J.5
Shillinglaw, W.6
Arnot, D.7
Uyeda, K.8
-
155
-
-
70349745715
-
Transcriptional regulation of mitochondrial glycerophosphate acyltransferase is mediated by distal promoter via ChREBP and SREBP-1
-
Guha P, Aneja KK, Shilpi RY, Haldar D. Transcriptional regulation of mitochondrial glycerophosphate acyltransferase is mediated by distal promoter via ChREBP and SREBP-1. Arch Biochem Biophys. 2009; 490:85-95
-
(2009)
Arch Biochem Biophys
, vol.490
, pp. 85-95
-
-
Guha, P.1
Aneja, K.K.2
Shilpi, R.Y.3
Haldar, D.4
-
156
-
-
84856756928
-
The role of fructose-enriched diets in mechanisms of nonalcoholic fatty liver disease
-
Nomura K, Yamanouchi T. The role of fructose-enriched diets in mechanisms of nonalcoholic fatty liver disease. J Nutr Biochem. 2012;23:203-8.
-
(2012)
J Nutr Biochem
, vol.23
, pp. 203-208
-
-
Nomura, K.1
Yamanouchi, T.2
-
157
-
-
0037216466
-
Hepatic de novo lipogenesis in normoinsulinemic and hyperinsulinemic subjects consuming high-fat, low-carbohydrate and low-fat, high-carbohydrate isoenergetic diets
-
Schwarz J-M, Linfoot P, Dare D, Aghajanian K. Hepatic de novo lipogenesis in normoinsulinemic and hyperinsulinemic subjects consuming high-fat, low-carbohydrate and low-fat, high-carbohydrate isoenergetic diets. Am J Clin Nutr. 2003;77:43-50.
-
(2003)
Am J Clin Nutr
, vol.77
, pp. 43-50
-
-
Schwarz, J.-M.1
Linfoot, P.2
Dare, D.3
Aghajanian, K.4
-
158
-
-
53349153430
-
Liver X receptor in cooperation with SREBP-1c is a major lipid synthesis regulator in nonalcoholic fatty liver disease
-
Higuchi N, Kato M, Shundo Y, Tajiri H, Tanaka M, Yamashita N, Kohjima M, Kotoh K, Nakamuta M, Takayanagi R, et al. Liver X receptor in cooperation with SREBP-1c is a major lipid synthesis regulator in nonalcoholic fatty liver disease. Hepatol Res. 2008;38:1122-9.
-
(2008)
Hepatol Res
, vol.38
, pp. 1122-1129
-
-
Higuchi, N.1
Kato, M.2
Shundo, Y.3
Tajiri, H.4
Tanaka, M.5
Yamashita, N.6
Kohjima, M.7
Kotoh, K.8
Nakamuta, M.9
Takayanagi, R.10
-
159
-
-
33847006599
-
The liver X receptor (LXR) and hepatic lipogenesis. The carbohydrate-response element-binding protein is a target gene of LXR
-
Cha J-Y, Repa JJ. The liver X receptor (LXR) and hepatic lipogenesis. The carbohydrate-response element-binding protein is a target gene of LXR. J Biol Chem. 2007;282:743-51.
-
(2007)
J Biol Chem
, vol.282
, pp. 743-751
-
-
Cha, J.-Y.1
Repa, J.J.2
-
160
-
-
85047694456
-
Bile acids lower triglyceride levels via a pathway involving FXR, SHP, and SREBP-1c
-
Watanabe M, Houten SM, Wang L, Moschetta A, Mangelsdorf DJ, Heyman RA, Moore DD, Auwerx J. Bile acids lower triglyceride levels via a pathway involving FXR, SHP, and SREBP-1c. J Clin Invest. 2004; 113:1408-18.
-
(2004)
J Clin Invest
, vol.113
, pp. 1408-1418
-
-
Watanabe, M.1
Houten, S.M.2
Wang, L.3
Moschetta, A.4
Mangelsdorf, D.J.5
Heyman, R.A.6
Moore, D.D.7
Auwerx, J.8
-
161
-
-
80054956019
-
Farnesol, an isoprenoid, improves metabolic abnormalities in mice via both PPARa-dependent and -independent pathways
-
Goto T, Kim Y-I, Funakoshi K, Teraminami A, Uemura T, Hirai S, Lee J-Y, Makishima M, Nakata R, Inoue H, et al. Farnesol, an isoprenoid, improves metabolic abnormalities in mice via both PPARa-dependent and -independent pathways. Am J Physiol Endocrinol Metab. 2011; 301:E1022-32.
-
(2011)
Am J Physiol Endocrinol Metab
, vol.301
, pp. E1022-E1032
-
-
Goto, T.1
Kim, Y.-I.2
Funakoshi, K.3
Teraminami, A.4
Uemura, T.5
Hirai, S.6
Lee, J.-Y.7
Makishima, M.8
Nakata, R.9
Inoue, H.10
-
162
-
-
33845984572
-
Aberrant hepatic expression of PPARgamma2 stimulates hepatic lipogenesis in a mouse model of obesity, insulin resistance, dyslipidemia, and hepatic steatosis
-
Zhang Y-L, Hernandez-Ono A, Siri P, Weisberg S, Conlon D, Graham MJ, Crooke RM, Huang L-S, Ginsberg HN. Aberrant hepatic expression of PPARgamma2 stimulates hepatic lipogenesis in a mouse model of obesity, insulin resistance, dyslipidemia, and hepatic steatosis. J Biol Chem. 2006;281:37603-15.
-
(2006)
J Biol Chem
, vol.281
, pp. 37603-37615
-
-
Zhang, Y.-L.1
Hernandez-Ono, A.2
Siri, P.3
Weisberg, S.4
Conlon, D.5
Graham, M.J.6
Crooke, R.M.7
Huang, L.-S.8
Ginsberg, H.N.9
-
164
-
-
0141446024
-
Liver peroxisome proliferator-activated receptor gamma contributes to hepatic steatosis, triglyceride clearance, and regulation of body fat mass
-
Gavrilova O, Haluzik M, Matsusue K, Cutson JJ, Johnson L, Dietz KR, Nicol CJ, Vinson C, Gonzalez FJ, Reitman ML. Liver peroxisome proliferator-activated receptor gamma contributes to hepatic steatosis, triglyceride clearance, and regulation of body fat mass. J Biol Chem. 2003;278:34268-76.
-
(2003)
J Biol Chem
, vol.278
, pp. 34268-34276
-
-
Gavrilova, O.1
Haluzik, M.2
Matsusue, K.3
Cutson, J.J.4
Johnson, L.5
Dietz, K.R.6
Nicol, C.J.7
Vinson, C.8
Gonzalez, F.J.9
Reitman, M.L.10
-
165
-
-
33744515637
-
FoxO1 regulates multiple metabolic pathways in the liver: effects on gluconeogenic, glycolytic, and lipogenic gene expression
-
Zhang W, Patil S, Chauhan B, Guo S, Powell DR, Le J, Klotsas A, Matika R, Xiao X, Franks R, et al. FoxO1 regulates multiple metabolic pathways in the liver: effects on gluconeogenic, glycolytic, and lipogenic gene expression. J Biol Chem. 2006;281:10105-17.
-
(2006)
J Biol Chem
, vol.281
, pp. 10105-10117
-
-
Zhang, W.1
Patil, S.2
Chauhan, B.3
Guo, S.4
Powell, D.R.5
Le, J.6
Klotsas, A.7
Matika, R.8
Xiao, X.9
Franks, R.10
-
166
-
-
84862004148
-
FoxO1 inhibits sterol regulatory element-binding protein-1c (SREBP-1c) gene expression via transcription factors Sp1 and SREBP-1c
-
Deng X, Zhang W, O-Sullivan I, Williams JB, Dong Q, Park EA, Raghow R, Unterman TG, Elam MB. FoxO1 inhibits sterol regulatory element-binding protein-1c (SREBP-1c) gene expression via transcription factors Sp1 and SREBP-1c. J Biol Chem. 2012;287:20132-43.
-
(2012)
J Biol Chem
, vol.287
, pp. 20132-20143
-
-
Deng, X.1
Zhang, W.2
O-Sullivan, I.3
Williams, J.B.4
Dong, Q.5
Park, E.A.6
Raghow, R.7
Unterman, T.G.8
Elam, M.B.9
-
167
-
-
68049091095
-
LXRalpha activation perturbs hepatic insulin signaling and stimulates production of apolipoprotein B-containing lipoproteins
-
Basciano H, Miller A, Baker C, Naples M, Adeli K. LXRalpha activation perturbs hepatic insulin signaling and stimulates production of apolipoprotein B-containing lipoproteins. Am J Physiol Gastrointest Liver Physiol. 2009;297:G323-32.
-
(2009)
Am J Physiol Gastrointest Liver Physiol
, vol.297
, pp. G323-G332
-
-
Basciano, H.1
Miller, A.2
Baker, C.3
Naples, M.4
Adeli, K.5
-
168
-
-
84863393589
-
The Scap/SREBP pathway is essential for developing diabetic fatty liver and carbohydrate-induced hypertriglyceridemia in animals
-
Moon Y-A, Liang G, Xie X, Frank-Kamenetsky M, Fitzgerald K, Koteliansky V, Brown MS, Goldstein JL, Horton JD. The Scap/SREBP pathway is essential for developing diabetic fatty liver and carbohydrate-induced hypertriglyceridemia in animals. Cell Metab. 2012;15:240-6.
-
(2012)
Cell Metab
, vol.15
, pp. 240-246
-
-
Moon, Y.-A.1
Liang, G.2
Xie, X.3
Frank-Kamenetsky, M.4
Fitzgerald, K.5
Koteliansky, V.6
Brown, M.S.7
Goldstein, J.L.8
Horton, J.D.9
-
169
-
-
45749133797
-
FoxO1 mediates insulin-dependent regulation of hepatic VLDL production in mice
-
Kamagate A, Qu S, Perdomo G, Su D, Kim DH, Slusher S, Meseck M, Dong HH. FoxO1 mediates insulin-dependent regulation of hepatic VLDL production in mice. J Clin Invest. 2008;118:2347-64.
-
(2008)
J Clin Invest
, vol.118
, pp. 2347-2364
-
-
Kamagate, A.1
Qu, S.2
Perdomo, G.3
Su, D.4
Kim, D.H.5
Slusher, S.6
Meseck, M.7
Dong, H.H.8
-
170
-
-
77954925939
-
Impaired-inactivation of FoxO1 contributes to glucose-mediated increases in serum very lowdensity lipoprotein
-
Wu K, Cappel D, Martinez M, Stafford JM. Impaired-inactivation of FoxO1 contributes to glucose-mediated increases in serum very lowdensity lipoprotein. Endocrinology. 2010;151:3566-76.
-
(2010)
Endocrinology
, vol.151
, pp. 3566-3576
-
-
Wu, K.1
Cappel, D.2
Martinez, M.3
Stafford, J.M.4
-
171
-
-
77956244443
-
Hepatic FoxO1 ablation exacerbates lipid abnormalities during hyperglycemia
-
Haeusler RA, Han S, Accili D. Hepatic FoxO1 ablation exacerbates lipid abnormalities during hyperglycemia. J Biol Chem. 2010;285:26861-8.
-
(2010)
J Biol Chem
, vol.285
, pp. 26861-26868
-
-
Haeusler, R.A.1
Han, S.2
Accili, D.3
-
172
-
-
84859986058
-
Increased atherosclerosis and endothelial dysfunction in mice bearing constitutively deacetylated alleles of Foxo1 gene
-
Qiang L, Tsuchiya K, Kim-Muller J-Y, Lin HV, Welch C, Accili D. Increased atherosclerosis and endothelial dysfunction in mice bearing constitutively deacetylated alleles of Foxo1 gene. J Biol Chem. 2012; 287:13944-51.
-
(2012)
J Biol Chem
, vol.287
, pp. 13944-13951
-
-
Qiang, L.1
Tsuchiya, K.2
Kim-Muller, J.-Y.3
Lin, H.V.4
Welch, C.5
Accili, D.6
-
173
-
-
84884820652
-
Regulation of autophagy by stress-responsive transcription factors
-
Epub, May 30
-
Pietrocola F, Izzo V, Niso-Santano M, Vacchelli E, Galluzzi L, Maiuri MC, Kroemer G. Regulation of autophagy by stress-responsive transcription factors. Semin Cancer Biol. Epub 2013 May 30.
-
(2013)
Semin Cancer Biol
-
-
Pietrocola, F.1
Izzo, V.2
Niso-Santano, M.3
Vacchelli, E.4
Galluzzi, L.5
Maiuri, M.C.6
Kroemer, G.7
-
174
-
-
84864878724
-
Modulation of glutamine metabolism by the PI(3)K-PKB-FOXO network regulates autophagy
-
van der Vos KE, Eliasson P, Proikas-Cezanne T, Vervoort SJ, van Boxtel R, Putker M, van Zutphen IJ, Mauthe M, Zellmer S, Pals C, et al. Modulation of glutamine metabolism by the PI(3)K-PKB-FOXO network regulates autophagy. Nat Cell Biol. 2012;14:829-37.
-
(2012)
Nat Cell Biol
, vol.14
, pp. 829-837
-
-
van der Vos, K.E.1
Eliasson, P.2
Proikas-Cezanne, T.3
Vervoort, S.J.4
van Boxtel, R.5
Putker, M.6
van Zutphen, I.J.7
Mauthe, M.8
Zellmer, S.9
Pals, C.10
-
175
-
-
77954225200
-
Cytosolic FoxO1 is essential for the induction of autophagy and tumour suppressor activity
-
Zhao Y, Yang J, Liao W, Liu X, Zhang H, Wang S, Wang D, Feng J, Yu L, Zhu W-G. Cytosolic FoxO1 is essential for the induction of autophagy and tumour suppressor activity. Nat Cell Biol. 2010;12:665-75.
-
(2010)
Nat Cell Biol
, vol.12
, pp. 665-675
-
-
Zhao, Y.1
Yang, J.2
Liao, W.3
Liu, X.4
Zhang, H.5
Wang, S.6
Wang, D.7
Feng, J.8
Yu, L.9
Zhu, W.-G.10
-
176
-
-
0023789884
-
Identification by amino acid sequencing of three major regulatory phosphorylation sites on rat acetyl-CoA carboxylase
-
Munday MR, Campbell DG, Carling D, Hardie DG. Identification by amino acid sequencing of three major regulatory phosphorylation sites on rat acetyl-CoA carboxylase. Eur J Biochem. 1988;175:331-8.
-
(1988)
Eur J Biochem
, vol.175
, pp. 331-338
-
-
Munday, M.R.1
Campbell, D.G.2
Carling, D.3
Hardie, D.G.4
-
177
-
-
0025192341
-
Location and function of three sites phosphorylated on rat acetyl-CoA carboxylase by the AMP-activated protein kinase
-
Davies SP, Sim AT, Hardie DG. Location and function of three sites phosphorylated on rat acetyl-CoA carboxylase by the AMP-activated protein kinase. Eur J Biochem. 1990;187:183-90.
-
(1990)
Eur J Biochem
, vol.187
, pp. 183-190
-
-
Davies, S.P.1
Sim, A.T.2
Hardie, D.G.3
-
178
-
-
15444339308
-
Phosphorylation of rat muscle acetyl-CoA carboxylase by AMP-activated protein kinase and protein kinase A
-
Winder WW, Wilson HA, Hardie DG, Rasmussen BB, Hutber CA, Call GB, Clayton RD, Conley LM, Yoon S, Zhou B. Phosphorylation of rat muscle acetyl-CoA carboxylase by AMP-activated protein kinase and protein kinase A. J Appl Physiol. 1997;82:219-25.
-
(1997)
J Appl Physiol
, vol.82
, pp. 219-225
-
-
Winder, W.W.1
Wilson, H.A.2
Hardie, D.G.3
Rasmussen, B.B.4
Hutber, C.A.5
Call, G.B.6
Clayton, R.D.7
Conley, L.M.8
Yoon, S.9
Zhou, B.10
-
179
-
-
0037031840
-
Coordinate regulation of malonyl-CoA decarboxylase, sn-glycerol-3-phosphate acyltransferase, and acetyl-CoA carboxylase by AMP-activated protein kinase in rat tissues in response to exercise
-
Park H, Kaushik VK, Constant S, Prentki M, Przybytkowski E, Ruderman NB, Saha AK. Coordinate regulation of malonyl-CoA decarboxylase, sn-glycerol-3-phosphate acyltransferase, and acetyl-CoA carboxylase by AMP-activated protein kinase in rat tissues in response to exercise. J Biol Chem. 2002;277:32571-7.
-
(2002)
J Biol Chem
, vol.277
, pp. 32571-32577
-
-
Park, H.1
Kaushik, V.K.2
Constant, S.3
Prentki, M.4
Przybytkowski, E.5
Ruderman, N.B.6
Saha, A.K.7
-
180
-
-
0033559856
-
AMP-activated kinase reciprocally regulates triacylglycerol synthesis and fatty acid oxidation in liver and muscle: evidence that sn-glycerol-3-phosphate acyltransferase is a novel target
-
Muoio DM, Seefeld K, Witters LA, Coleman RA. AMP-activated kinase reciprocally regulates triacylglycerol synthesis and fatty acid oxidation in liver and muscle: evidence that sn-glycerol-3-phosphate acyltransferase is a novel target. Biochem J. 1999;338:783-91.
-
(1999)
Biochem J
, vol.338
, pp. 783-791
-
-
Muoio, D.M.1
Seefeld, K.2
Witters, L.A.3
Coleman, R.A.4
-
181
-
-
34547545892
-
AMP-activated protein kinase (AMPK) action in skeletal muscle via direct phosphorylation of PGC-1alpha
-
Jäger S, Handschin C, St-Pierre J, Spiegelman BM. AMP-activated protein kinase (AMPK) action in skeletal muscle via direct phosphorylation of PGC-1alpha. Proc Natl Acad Sci USA. 2007;104:12017-22.
-
(2007)
Proc Natl Acad Sci USA
, vol.104
, pp. 12017-12022
-
-
Jäger, S.1
Handschin, C.2
St-Pierre, J.3
Spiegelman, B.M.4
-
182
-
-
77958595135
-
SIRT1 deacetylates and inhibits SREBP-1C activity in regulation of hepatic lipid metabolism
-
Ponugoti B, Kim D-H, Xiao Z, Smith Z, Miao J, Zang M, Wu S-Y, Chiang C-M, Veenstra TD, Kemper JK. SIRT1 deacetylates and inhibits SREBP-1C activity in regulation of hepatic lipid metabolism. J Biol Chem. 2010;285:33959-70.
-
(2010)
J Biol Chem
, vol.285
, pp. 33959-33970
-
-
Ponugoti, B.1
Kim, D.-H.2
Xiao, Z.3
Smith, Z.4
Miao, J.5
Zang, M.6
Wu, S.-Y.7
Chiang, C.-M.8
Veenstra, T.D.9
Kemper, J.K.10
-
183
-
-
77954488637
-
Conserved role of SIRT1 orthologs in fasting-dependent inhibition of the lipid/cholesterol regulator SREBP
-
Walker AK, Yang F, Jiang K, Ji J-Y, Watts JL, Purushotham A, Boss O, Hirsch ML, Ribich S, Smith JJ. Conserved role of SIRT1 orthologs in fasting-dependent inhibition of the lipid/cholesterol regulator SREBP. Genes Dev. 2010;24:1403-17.
-
(2010)
Genes Dev
, vol.24
, pp. 1403-1417
-
-
Walker, A.K.1
Yang, F.2
Jiang, K.3
Ji, J.-Y.4
Watts, J.L.5
Purushotham, A.6
Boss, O.7
Hirsch, M.L.8
Ribich, S.9
Smith, J.J.10
-
184
-
-
70350606061
-
FXR acetylation is normally dynamically regulated by p300 and SIRT1 but constitutively elevated in metabolic disease states
-
Kemper JK, Xiao Z, Ponugoti B, Miao J, Fang S, Kanamaluru D, Tsang S, Wu S-Y, Chiang C-M, Veenstra TD. FXR acetylation is normally dynamically regulated by p300 and SIRT1 but constitutively elevated in metabolic disease states. Cell Metab. 2009;10:392-404.
-
(2009)
Cell Metab
, vol.10
, pp. 392-404
-
-
Kemper, J.K.1
Xiao, Z.2
Ponugoti, B.3
Miao, J.4
Fang, S.5
Kanamaluru, D.6
Tsang, S.7
Wu, S.-Y.8
Chiang, C.-M.9
Veenstra, T.D.10
-
185
-
-
14544282413
-
Nutrient control of glucose homeostasis through a complex of PGC-1a and SIRT1
-
Rodgers JT, Lerin C, Haas W, Gygi SP, Spiegelman BM, Puigserver P. Nutrient control of glucose homeostasis through a complex of PGC-1a and SIRT1. Nature. 2005;434:113-8.
-
(2005)
Nature
, vol.434
, pp. 113-118
-
-
Rodgers, J.T.1
Lerin, C.2
Haas, W.3
Gygi, S.P.4
Spiegelman, B.M.5
Puigserver, P.6
-
186
-
-
63449112017
-
Hepatocyte-specific deletion of SIRT1 alters fatty acid metabolism and results in hepatic steatosis and inflammation
-
Purushotham A, Schug TT, Xu Q, Surapureddi S, Guo X, Li X. Hepatocyte-specific deletion of SIRT1 alters fatty acid metabolism and results in hepatic steatosis and inflammation. Cell Metab. 2009;9:327-38.
-
(2009)
Cell Metab
, vol.9
, pp. 327-338
-
-
Purushotham, A.1
Schug, T.T.2
Xu, Q.3
Surapureddi, S.4
Guo, X.5
Li, X.6
-
187
-
-
84875382650
-
Glucagon-induced acetylation of Foxa2 regulates hepatic lipid metabolism
-
von Meyenn F, Porstmann T, Gasser E, Selevsek N, Schmidt A, Aebersold R, Stoffel M. Glucagon-induced acetylation of Foxa2 regulates hepatic lipid metabolism. Cell Metab. 2013;17:436-47.
-
(2013)
Cell Metab
, vol.17
, pp. 436-447
-
-
von Meyenn, F.1
Porstmann, T.2
Gasser, E.3
Selevsek, N.4
Schmidt, A.5
Aebersold, R.6
Stoffel, M.7
-
188
-
-
1342264308
-
Mammalian SIRT1 represses forkhead transcription factors
-
Motta MC, Divecha N, Lemieux M, Kamel C, Chen D, GuW, Bultsma Y, McBurney M, Guarente L. Mammalian SIRT1 represses forkhead transcription factors. Cell. 2004;116:551-63.
-
(2004)
Cell
, vol.116
, pp. 551-563
-
-
Motta, M.C.1
Divecha, N.2
Lemieux, M.3
Kamel, C.4
Chen, D.G.5
Bultsma, Y.6
McBurney, M.7
Guarente, L.8
-
189
-
-
84882935541
-
Sirtuins' modulation of autophagy
-
Ng F, Tang BL. Sirtuins' modulation of autophagy. J Cell Physiol. 2013;228:2262-70.
-
(2013)
J Cell Physiol
, vol.228
, pp. 2262-2270
-
-
Ng, F.1
Tang, B.L.2
-
190
-
-
80053564714
-
CREB and ChREBP oppositely regulate SIRT1 expression in response to energy availability
-
Noriega LG, Feige JN, Canto C, Yamamoto H, Yu J, Herman MA, Mataki C, Kahn BB, Auwerx J. CREB and ChREBP oppositely regulate SIRT1 expression in response to energy availability. EMBO Rep. 2011; 12:1069-76.
-
(2011)
EMBO Rep
, vol.12
, pp. 1069-1076
-
-
Noriega, L.G.1
Feige, J.N.2
Canto, C.3
Yamamoto, H.4
Yu, J.5
Herman, M.A.6
Mataki, C.7
Kahn, B.B.8
Auwerx, J.9
-
191
-
-
78649509214
-
SIRT3 deacetylates mitochondrial 3-hydroxy-3-methylglutaryl CoA synthase 2 and regulates ketone body production
-
Shimazu T, Hirschey MD, Hua L, Dittenhafer-Reed KE, Schwer B, Lombard DB, Li Y, Bunkenborg J, Alt FW, Denu JM, et al. SIRT3 deacetylates mitochondrial 3-hydroxy-3-methylglutaryl CoA synthase 2 and regulates ketone body production. Cell Metab. 2010;12:654-61.
-
(2010)
Cell Metab
, vol.12
, pp. 654-661
-
-
Shimazu, T.1
Hirschey, M.D.2
Hua, L.3
Dittenhafer-Reed, K.E.4
Schwer, B.5
Lombard, D.B.6
Li, Y.7
Bunkenborg, J.8
Alt, F.W.9
Denu, J.M.10
-
192
-
-
0034910847
-
Genetic basis of mitochondrial HMGCoA synthase deficiency
-
Aledo R, Zschocke J, Pié J, Mir C, Fiesel S, Mayatepek E, Hoffmann GF, Casals N, Hegardt FG. Genetic basis of mitochondrial HMGCoA synthase deficiency. Hum Genet. 2001;109:19-23.
-
(2001)
Hum Genet
, vol.109
, pp. 19-23
-
-
Aledo, R.1
Zschocke, J.2
Pié, J.3
Mir, C.4
Fiesel, S.5
Mayatepek, E.6
Hoffmann, G.F.7
Casals, N.8
Hegardt, F.G.9
-
193
-
-
0031584530
-
Fasting hypoketotic coma in a child with deficiency of mitochondrial 3-hydroxy-3-methylglutaryl-CoA synthase
-
Thompson GN, Hsu BY, Pitt JJ, Treacy E, Stanley CA. Fasting hypoketotic coma in a child with deficiency of mitochondrial 3-hydroxy-3-methylglutaryl-CoA synthase. N Engl J Med. 1997;337:1203-7.
-
(1997)
N Engl J Med
, vol.337
, pp. 1203-1207
-
-
Thompson, G.N.1
Hsu, B.Y.2
Pitt, J.J.3
Treacy, E.4
Stanley, C.A.5
-
194
-
-
79961165137
-
mTOR Complex 1 regulates Lipin 1 Localization to control the SREBP pathway
-
Peterson TR, Sengupta SS, Harris TE, Carmack AE, Kang SA, Balderas E, Guertin DA, Madden KL, Carpenter AE, Finck BN, et al. mTOR Complex 1 regulates Lipin 1 Localization to control the SREBP pathway. Cell. 2011;146:408-20.
-
(2011)
Cell
, vol.146
, pp. 408-420
-
-
Peterson, T.R.1
Sengupta, S.S.2
Harris, T.E.3
Carmack, A.E.4
Kang, S.A.5
Balderas, E.6
Guertin, D.A.7
Madden, K.L.8
Carpenter, A.E.9
Finck, B.N.10
-
195
-
-
78650848337
-
mTORC1 controls fasting-induced ketogenesis and its modulation by ageing
-
Sengupta S, Peterson TR, Laplante M, Oh S, Sabatini DM. mTORC1 controls fasting-induced ketogenesis and its modulation by ageing. Nature. 2010;468:1100-4.
-
(2010)
Nature
, vol.468
, pp. 1100-1104
-
-
Sengupta, S.1
Peterson, T.R.2
Laplante, M.3
Oh, S.4
Sabatini, D.M.5
-
196
-
-
84883548896
-
Insulin inhibits lipolysis in adipocytes via the evolutionary conserved mTORC1-Egr1-ATGL-mediated pathway
-
Chakrabarti P, Kim JY, Singh M, Shin Y-K, Kim J, Kumbrink J, Wu Y, Lee M-J, Kirsch KH, Fried SK. Insulin inhibits lipolysis in adipocytes via the evolutionary conserved mTORC1-Egr1-ATGL-mediated pathway. Mol Cell Biol. 2013;33:3659-66.
-
(2013)
Mol Cell Biol
, vol.33
, pp. 3659-3666
-
-
Chakrabarti, P.1
Kim, J.Y.2
Singh, M.3
Shin, Y.-K.4
Kim, J.5
Kumbrink, J.6
Wu, Y.7
Lee, M.-J.8
Kirsch, K.H.9
Fried, S.K.10
-
197
-
-
0032512636
-
Tor, a phosphatidylinositol kinase homologue, controls autophagy in yeast
-
Noda T, Ohsumi Y. Tor, a phosphatidylinositol kinase homologue, controls autophagy in yeast. J Biol Chem. 1998;273:3963-6.
-
(1998)
J Biol Chem
, vol.273
, pp. 3963-3966
-
-
Noda, T.1
Ohsumi, Y.2
-
198
-
-
0028115062
-
Insulin regulation of triacylglycerol-rich lipoprotein synthesis and secretion
-
Sparks JD, Sparks CE. Insulin regulation of triacylglycerol-rich lipoprotein synthesis and secretion. Biochim Biophys Acta. 1994;1215:9-32.
-
(1994)
Biochim Biophys Acta
, vol.1215
, pp. 9-32
-
-
Sparks, J.D.1
Sparks, C.E.2
-
199
-
-
80052388637
-
Increased very low density lipoprotein (VLDL) secretion, hepatic steatosis, and insulin resistance
-
Choi SH, Ginsberg HN. Increased very low density lipoprotein (VLDL) secretion, hepatic steatosis, and insulin resistance. Trends Endocrinol Metab. 2011;22:353-63.
-
(2011)
Trends Endocrinol Metab
, vol.22
, pp. 353-363
-
-
Choi, S.H.1
Ginsberg, H.N.2
-
200
-
-
84860593304
-
Activation of ER stress and mTORC1 suppresses hepatic sortilin-1 levels in obese mice
-
Ai D, Baez JM, Jiang H, Conlon DM, Hernandez-Ono A, Frank-Kamenetsky M, Milstein S, Fitzgerald K, Murphy AJ, Woo CW, et al. Activation of ER stress and mTORC1 suppresses hepatic sortilin-1 levels in obese mice. J Clin Invest. 2012;122:1677-87.
-
(2012)
J Clin Invest
, vol.122
, pp. 1677-1687
-
-
Ai, D.1
Baez, J.M.2
Jiang, H.3
Conlon, D.M.4
Hernandez-Ono, A.5
Frank-Kamenetsky, M.6
Milstein, S.7
Fitzgerald, K.8
Murphy, A.J.9
Woo, C.W.10
-
202
-
-
79952451443
-
Obesity, insulin resistance and free fatty acids
-
Boden G. Obesity, insulin resistance and free fatty acids. Curr Opin Endocrinol Diabetes Obes. 2011;18:139-43.
-
(2011)
Curr Opin Endocrinol Diabetes Obes
, vol.18
, pp. 139-143
-
-
Boden, G.1
-
203
-
-
20144375077
-
Real-time assessment of postprandial fat storage in liver and skeletal muscle in health and type 2 diabetes
-
Ravikumar B, Carey PE, Snaar JEM, Deelchand DK, Cook DB, Neely RDG, English PT, Firbank MJ, Morris PG, Taylor R. Real-time assessment of postprandial fat storage in liver and skeletal muscle in health and type 2 diabetes. Am J Physiol Endocrinol Metab. 2005;288:E789-97.
-
(2005)
Am J Physiol Endocrinol Metab
, vol.288
, pp. E789-E797
-
-
Ravikumar, B.1
Carey, P.E.2
Snaar, J.E.M.3
Deelchand, D.K.4
Cook, D.B.5
Neely, R.D.G.6
English, P.T.7
Firbank, M.J.8
Morris, P.G.9
Taylor, R.10
-
204
-
-
84878355072
-
In vivo postprandial lipid partitioning in liver and skeletal muscle in prediabetic and diabetic rats
-
Jonkers RAM, van Loon LJC, Nicolay K, Prompers JJ. In vivo postprandial lipid partitioning in liver and skeletal muscle in prediabetic and diabetic rats. Diabetologia. 2013;56:618-26.
-
(2013)
Diabetologia
, vol.56
, pp. 618-626
-
-
Jonkers, R.A.M.1
van Loon, L.J.C.2
Nicolay, K.3
Prompers, J.J.4
-
205
-
-
37849028864
-
Nutritional assessment and hepatic fatty acid composition in non-alcoholic fatty liver disease (NAFLD): a cross-sectional study
-
Allard JP, Aghdassi E, Mohammed S, Raman M, Avand G, Jalali P, Kandasamy T, Prayitno N, Sherman M, et al. Nutritional assessment and hepatic fatty acid composition in non-alcoholic fatty liver disease (NAFLD): a cross-sectional study. J Hepatol. 2008;48:300-7.
-
(2008)
J Hepatol
, vol.48
, pp. 300-307
-
-
Allard, J.P.1
Aghdassi, E.2
Mohammed, S.3
Raman, M.4
Avand, G.5
Jalali, P.6
Kandasamy, T.7
Prayitno, N.8
Sherman, M.9
-
206
-
-
78651278905
-
Production, purification and characterization of adeno-associated vectors
-
Ayuso E, Mingozzi F, Bosch F. Production, purification and characterization of adeno-associated vectors. Curr Gene Ther. 2010;10:423-36.
-
(2010)
Curr Gene Ther
, vol.10
, pp. 423-436
-
-
Ayuso, E.1
Mingozzi, F.2
Bosch, F.3
-
207
-
-
2942706241
-
Increase in long-chain polyunsaturated fatty acid n-6/n-3 ratio in relation to hepatic steatosis in patients with non-alcoholic fatty liver disease
-
Araya J, Rodrigo R, Videla LA, Thielemann L, Orellana M, Pettinelli P, Poniachik J. Increase in long-chain polyunsaturated fatty acid n-6/n-3 ratio in relation to hepatic steatosis in patients with non-alcoholic fatty liver disease. Clin Sci Lond Engl. 2004;106:635-43.
-
(2004)
Clin Sci Lond Engl
, vol.106
, pp. 635-643
-
-
Araya, J.1
Rodrigo, R.2
Videla, L.A.3
Thielemann, L.4
Orellana, M.5
Pettinelli, P.6
Poniachik, J.7
-
208
-
-
34248581989
-
Disordered lipid metabolism and the pathogenesis of insulin resistance
-
Savage DB, Petersen KF, Shulman GI. Disordered lipid metabolism and the pathogenesis of insulin resistance. Physiol Rev. 2007;87:507-20.
-
(2007)
Physiol Rev
, vol.87
, pp. 507-520
-
-
Savage, D.B.1
Petersen, K.F.2
Shulman, G.I.3
-
209
-
-
84856415487
-
The role of mitochondria in insulin resistance and type 2 diabetes mellitus
-
Szendroedi J, Phielix E, Roden M. The role of mitochondria in insulin resistance and type 2 diabetes mellitus. Nat Rev Endocrinol. 2012;8:92-103.
-
(2012)
Nat Rev Endocrinol
, vol.8
, pp. 92-103
-
-
Szendroedi, J.1
Phielix, E.2
Roden, M.3
-
210
-
-
3543029821
-
Mechanism of hepatic insulin resistance in non-alcoholic fatty liver disease
-
Samuel VT, Liu ZX, Qu X, Elder BD, Bilz S, Befroy D, Romanelli AJ, Shulman GI. Mechanism of hepatic insulin resistance in non-alcoholic fatty liver disease. J Biol Chem. 2004;279:32345-53.
-
(2004)
J Biol Chem
, vol.279
, pp. 32345-32353
-
-
Samuel, V.T.1
Liu, Z.X.2
Qu, X.3
Elder, B.D.4
Bilz, S.5
Befroy, D.6
Romanelli, A.J.7
Shulman, G.I.8
-
211
-
-
0035084699
-
Nonalcoholic steatohepatitis: association of insulin resistance and mitochondrial abnormalities
-
Sanyal AJ, Campbell-Sargent C, Mirshahi F, Rizzo WB, Contos MJ, Sterling RK, Luketic VA, Shiffman ML, Clore JN. Nonalcoholic steatohepatitis: association of insulin resistance and mitochondrial abnormalities. Gastroenterology. 2001;120:1183-92.
-
(2001)
Gastroenterology
, vol.120
, pp. 1183-1192
-
-
Sanyal, A.J.1
Campbell-Sargent, C.2
Mirshahi, F.3
Rizzo, W.B.4
Contos, M.J.5
Sterling, R.K.6
Luketic, V.A.7
Shiffman, M.L.8
Clore, J.N.9
-
212
-
-
20944450486
-
Insulin resistance in non-diabetic patients with non-alcoholic fatty liver disease: sites and mechanisms
-
Bugianesi E, Gastaldelli A, Vanni E, Gambino R, Cassader M, Baldi S, Ponti V, Pagano G, Ferrannini E, Rizzetto M. Insulin resistance in non-diabetic patients with non-alcoholic fatty liver disease: sites and mechanisms. Diabetologia. 2005;48:634-42.
-
(2005)
Diabetologia
, vol.48
, pp. 634-642
-
-
Bugianesi, E.1
Gastaldelli, A.2
Vanni, E.3
Gambino, R.4
Cassader, M.5
Baldi, S.6
Ponti, V.7
Pagano, G.8
Ferrannini, E.9
Rizzetto, M.10
-
213
-
-
77957592767
-
Greater dietary fat oxidation in obese compared with lean men: an adaptive mechanism to prevent liver fat accumulation?
-
Hodson L, McQuaid SE, Humphreys SM, Milne R, Fielding BA, Frayn KN, Karpe F. Greater dietary fat oxidation in obese compared with lean men: an adaptive mechanism to prevent liver fat accumulation? Am J Physiol Endocrinol Metab. 2010;299:E584-92.
-
(2010)
Am J Physiol Endocrinol Metab
, vol.299
, pp. E584-E592
-
-
Hodson, L.1
McQuaid, S.E.2
Humphreys, S.M.3
Milne, R.4
Fielding, B.A.5
Frayn, K.N.6
Karpe, F.7
-
214
-
-
77956151046
-
Fatty acid metabolism in the liver, measured by positron emission tomography, is increased in obese individuals
-
Iozzo P, Bucci M, Roivainen A, Någren K, Järvisalo MJ, Kiss J, Guiducci L, Fielding B, Naum AG, Borra R, et al. Fatty acid metabolism in the liver, measured by positron emission tomography, is increased in obese individuals. Gastroenterology. 2010;139:846-56.
-
(2010)
Gastroenterology
, vol.139
, pp. 846-856
-
-
Iozzo, P.1
Bucci, M.2
Roivainen, A.3
Någren, K.4
Järvisalo, M.J.5
Kiss, J.6
Guiducci, L.7
Fielding, B.8
Naum, A.G.9
Borra, R.10
-
215
-
-
84861451144
-
Elevated TCA cycle function in the pathology of diet-induced hepatic insulin resistance and fatty liver
-
Satapati S, Sunny NE, Kucejova B, Fu X, He TT, Méndez-Lucas A, Shelton JM, Perales JC, Browning JD, Burgess SC. Elevated TCA cycle function in the pathology of diet-induced hepatic insulin resistance and fatty liver. J Lipid Res. 2012;53:1080-92.
-
(2012)
J Lipid Res
, vol.53
, pp. 1080-1092
-
-
Satapati, S.1
Sunny, N.E.2
Kucejova, B.3
Fu, X.4
He, T.T.5
Méndez-Lucas, A.6
Shelton, J.M.7
Perales, J.C.8
Browning, J.D.9
Burgess, S.C.10
-
216
-
-
82955239838
-
Excessive hepatic mitochondrial TCA cycle and gluconeogenesis in humans with nonalcoholic fatty liver disease
-
Sunny NE, Parks EJ, Browning JD, Burgess SC. Excessive hepatic mitochondrial TCA cycle and gluconeogenesis in humans with nonalcoholic fatty liver disease. Cell Metab. 2011;14:804-10.
-
(2011)
Cell Metab
, vol.14
, pp. 804-810
-
-
Sunny, N.E.1
Parks, E.J.2
Browning, J.D.3
Burgess, S.C.4
-
217
-
-
33644827082
-
Overproduction of large VLDL particles is driven by increased liver fat content in man
-
Adiels M, Taskinen M-R, Packard C, Caslake MJ, Soro-Paavonen A, Westerbacka J, Vehkavaara S, Häkkinen A, Olofsson S-O, Yki-Järvinen H, et al. Overproduction of large VLDL particles is driven by increased liver fat content in man. Diabetologia. 2006;49:755-65.
-
(2006)
Diabetologia
, vol.49
, pp. 755-765
-
-
Adiels, M.1
Taskinen, M.-R.2
Packard, C.3
Caslake, M.J.4
Soro-Paavonen, A.5
Westerbacka, J.6
Vehkavaara, S.7
Häkkinen, A.8
Olofsson, S.-O.9
Yki-Järvinen, H.10
-
218
-
-
38649111018
-
Alterations in adipose tissue and hepatic lipid kinetics in obese men and women with nonalcoholic fatty liver disease
-
Fabbrini E, Mohammed BS, Magkos F, Korenblat KM, Patterson BW, Klein S. Alterations in adipose tissue and hepatic lipid kinetics in obese men and women with nonalcoholic fatty liver disease. Gastroenterology. 2008;134:424-31.
-
(2008)
Gastroenterology
, vol.134
, pp. 424-431
-
-
Fabbrini, E.1
Mohammed, B.S.2
Magkos, F.3
Korenblat, K.M.4
Patterson, B.W.5
Klein, S.6
-
219
-
-
84868014062
-
Skeletal muscle insulin resistance promotes increased hepatic de novo lipogenesis, hyperlipidemia, and hepatic steatosis in the elderly
-
Flannery C, Dufour S, Rabøl R, Shulman GI, Petersen KF. Skeletal muscle insulin resistance promotes increased hepatic de novo lipogenesis, hyperlipidemia, and hepatic steatosis in the elderly. Diabetes. 2012;61:2711-7.
-
(2012)
Diabetes
, vol.61
, pp. 2711-2717
-
-
Flannery, C.1
Dufour, S.2
Rabøl, R.3
Shulman, G.I.4
Petersen, K.F.5
-
220
-
-
84874600898
-
De novo lipogenesis in human fat and liver is linked to ChREBP-b and metabolic health
-
Eissing L, Scherer T, Tödter K, Knippschild U, Greve JW, Buurman WA, Pinnschmidt HO, Rensen SS, Wolf AM, Bartelt A, et al. De novo lipogenesis in human fat and liver is linked to ChREBP-b and metabolic health. Nat Commun. 2013;4:1528.
-
(2013)
Nat Commun
, vol.4
, pp. 1528
-
-
Eissing, L.1
Scherer, T.2
Tödter, K.3
Knippschild, U.4
Greve, J.W.5
Buurman, W.A.6
Pinnschmidt, H.O.7
Rensen, S.S.8
Wolf, A.M.9
Bartelt, A.10
-
221
-
-
0344874201
-
Contribution of hepatic de novo lipogenesis and reesterification of plasma non esterified fatty acids to plasma triglyceride synthesis during non-alcoholic fatty liver disease
-
Diraison F, Moulin P, Beylot M. Contribution of hepatic de novo lipogenesis and reesterification of plasma non esterified fatty acids to plasma triglyceride synthesis during non-alcoholic fatty liver disease. Diabetes Metab. 2003;29:478-85.
-
(2003)
Diabetes Metab
, vol.29
, pp. 478-485
-
-
Diraison, F.1
Moulin, P.2
Beylot, M.3
-
222
-
-
84879864004
-
Reciprocal regulation of hepatic and adipose lipogenesis by liver x receptors in obesity and insulin resistance
-
Beaven SW, Matveyenko A, Wroblewski K, Chao L, Wilpitz D, Hsu TW, Lentz J, Drew B, Hevener AL, Tontonoz P. Reciprocal regulation of hepatic and adipose lipogenesis by liver x receptors in obesity and insulin resistance. Cell Metab. 2013;18:106-17.
-
(2013)
Cell Metab
, vol.18
, pp. 106-117
-
-
Beaven, S.W.1
Matveyenko, A.2
Wroblewski, K.3
Chao, L.4
Wilpitz, D.5
Hsu, T.W.6
Lentz, J.7
Drew, B.8
Hevener, A.L.9
Tontonoz, P.10
-
223
-
-
40549135297
-
Contribution of de novo fatty acid synthesis to hepatic steatosis and insulin resistance: lessons from genetically engineered mice
-
Postic C, Girard J. Contribution of de novo fatty acid synthesis to hepatic steatosis and insulin resistance: lessons from genetically engineered mice. J Clin Invest. 2008;118:829-38.
-
(2008)
J Clin Invest
, vol.118
, pp. 829-838
-
-
Postic, C.1
Girard, J.2
-
224
-
-
84876287362
-
Pharmacological promotion of autophagy alleviates steatosis and injury in alcoholic and non-alcoholic fatty liver conditions in mice
-
Lin C-W, Zhang H, Li M, Xiong X, Chen X, Chen X, Dong XC, Yin X-M. Pharmacological promotion of autophagy alleviates steatosis and injury in alcoholic and non-alcoholic fatty liver conditions in mice. J Hepatol. 2013;58:993-9.
-
(2013)
J Hepatol
, vol.58
, pp. 993-999
-
-
Lin, C.-W.1
Zhang, H.2
Li, M.3
Xiong, X.4
Chen, X.5
Chen, X.6
Dong, X.C.7
Yin, X.-M.8
-
225
-
-
84884984539
-
Mitochondrial adaptations and dysfunctions in nonalcoholic fatty liver disease
-
Epub, Jan 8
-
Begriche K, Massart J, Robin M-A, Bonnet F, Fromenty B. Mitochondrial adaptations and dysfunctions in nonalcoholic fatty liver disease. Hepatology. Epub 2013 Jan 8.
-
(2013)
Hepatology
-
-
Begriche, K.1
Massart, J.2
Robin, M.-A.3
Bonnet, F.4
Fromenty, B.5
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