메뉴 건너뛰기




Volumn 103, Issue 9, 1999, Pages 1287-1298

Analysis of the role of microsomal triglyceride transfer protein in the liver of tissue-specific knockout mice

Author keywords

[No Author keywords available]

Indexed keywords

CARRIER PROTEIN; VERY LOW DENSITY LIPOPROTEIN;

EID: 0344349000     PISSN: 00219738     EISSN: None     Source Type: Journal    
DOI: 10.1172/JCI6576     Document Type: Article
Times cited : (378)

References (62)
  • 1
    • 0030859321 scopus 로고    scopus 로고
    • Recent advances in elucidating the role of the microsomal triglyceride transfer protein in apolipoprotein B lipoprotein assembly
    • Gordon, D.A. 1997. Recent advances in elucidating the role of the microsomal triglyceride transfer protein in apolipoprotein B lipoprotein assembly. Curr. Opin. Lipidol. 8:131-137.
    • (1997) Curr. Opin. Lipidol. , vol.8 , pp. 131-137
    • Gordon, D.A.1
  • 2
    • 0032561425 scopus 로고    scopus 로고
    • An MTP inhibitor that normalizes atherogenic lipoprotein levels in WHHL rabbits
    • Wetterau, J.R., et al. 1998. An MTP inhibitor that normalizes atherogenic lipoprotein levels in WHHL rabbits. Science. 282:751-754.
    • (1998) Science , vol.282 , pp. 751-754
    • Wetterau, J.R.1
  • 3
    • 0344301949 scopus 로고    scopus 로고
    • Genes for apolipoprotein B and microsomal triglyceride transfer protein are expressed in the heart. Evidence that the heart has the capacity to synthesize and secrete lipoproteins
    • Nielsen, L.B., et al. 1998. Genes for apolipoprotein B and microsomal triglyceride transfer protein are expressed in the heart. Evidence that the heart has the capacity to synthesize and secrete lipoproteins. Circulation. 98:13-16.
    • (1998) Circulation , vol.98 , pp. 13-16
    • Nielsen, L.B.1
  • 4
    • 2642660445 scopus 로고    scopus 로고
    • Apo B100-containing lipoproteins are secreted by the heart
    • Borén, J., Véniant, M.M., and Young, S.G. 1998. Apo B100-containing lipoproteins are secreted by the heart J. Clin. Invest. 101:1197-1202.
    • (1998) J. Clin. Invest. , vol.101 , pp. 1197-1202
    • Borén, J.1    Véniant, M.M.2    Young, S.G.3
  • 5
    • 0032555195 scopus 로고    scopus 로고
    • Knockout of the abetalipoproteinemia gene in mice: Reduced lipoprotein secretion in heterozygotes and embryonic lethality in homozygotes
    • Raabe, M., et al. 1998. Knockout of the abetalipoproteinemia gene in mice: reduced lipoprotein secretion in heterozygotes and embryonic lethality in homozygotes. Proc. Natl. Acad. Sci. USA. 95:8686-8691.
    • (1998) Proc. Natl. Acad. Sci. USA , vol.95 , pp. 8686-8691
    • Raabe, M.1
  • 6
    • 0032959814 scopus 로고    scopus 로고
    • Estrogen induction of VLDLy assembly in egg-laying hens
    • Walzem, R.L., Hansen, R.J., Williams, D.L., and Hamilton, R.L. 1999. Estrogen induction of VLDLy assembly in egg-laying hens. J. Nutr. 129:4675-4725.
    • (1999) J. Nutr. , vol.129 , pp. 4675-4725
    • Walzem, R.L.1    Hansen, R.J.2    Williams, D.L.3    Hamilton, R.L.4
  • 7
    • 0021995612 scopus 로고
    • Purification and characterization of microsomal triglyceride and cholesteryl ester transfer protein from bovine liver microsomes
    • Wetterau J.R., and Zilversmit, D.B. 1985. Purification and characterization of microsomal triglyceride and cholesteryl ester transfer protein from bovine liver microsomes. Chem. Phys. Lipids. 38:205-222.
    • (1985) Chem. Phys. Lipids , vol.38 , pp. 205-222
    • Wetterau, J.R.1    Zilversmit, D.B.2
  • 8
    • 0027486706 scopus 로고
    • Mechanism of microsomal triglyceride transfer protein catalyzed lipid transport
    • Atzel, A., and Wetterau, J.R. 1993. Mechanism of microsomal triglyceride transfer protein catalyzed lipid transport. Biochemistry. 32:10444-10450.
    • (1993) Biochemistry , vol.32 , pp. 10444-10450
    • Atzel, A.1    Wetterau, J.R.2
  • 9
    • 0026052386 scopus 로고
    • Protein disulfide isomerase appears necessary to maintain the catalytically active structure of the microsomal triglyceride transfer protein
    • Wetterau, J.R., et al. 1991. Protein disulfide isomerase appears necessary to maintain the catalytically active structure of the microsomal triglyceride transfer protein. Biochemistry, 30:9728-9735.
    • (1991) Biochemistry , vol.30 , pp. 9728-9735
    • Wetterau, J.R.1
  • 10
    • 0026470990 scopus 로고
    • Absence of microsomal triglyceride transfer protein in individuals with abetalipoproteinemia
    • Wetterau, J.R., et al. 1992. Absence of microsomal triglyceride transfer protein in individuals with abetalipoproteinemia. Science. 258:999-1001.
    • (1992) Science , vol.258 , pp. 999-1001
    • Wetterau, J.R.1
  • 11
    • 0001903995 scopus 로고
    • Disorders of the biogenesis and secretion of lipoproteins containing the B apolipoproteins
    • C.R. Scriver, A.L. Beaudet, W.S. Sly, and D. Valle, editors. McGraw-Hill. New York, NY
    • Kane, J.P., and Havel, R.J. 1989. Disorders of the biogenesis and secretion of lipoproteins containing the B apolipoproteins. In The metabolic basis of inherited disease. 6th edition. C.R. Scriver, A.L. Beaudet, W.S. Sly, and D. Valle, editors. McGraw-Hill. New York, NY. 1139-1164.
    • (1989) The Metabolic Basis of Inherited Disease. 6th Edition , pp. 1139-1164
    • Kane, J.P.1    Havel, R.J.2
  • 12
    • 0027428820 scopus 로고
    • Cloning and gene defects in microsomal triglyceride transfer protein associated with abetalipoproteinaemia
    • Sharp, D., et al. 1993. Cloning and gene defects in microsomal triglyceride transfer protein associated with abetalipoproteinaemia. Nature. 365:65-69.
    • (1993) Nature , vol.365 , pp. 65-69
    • Sharp, D.1
  • 13
    • 0030001575 scopus 로고    scopus 로고
    • A novel abetalipoproteinemia genotype. Identification of a missense mutation in the 97-kDa subunit of the microsomal triglyceride transfer protein that prevents complex formation with protein disulfide isomerase
    • Rehberg, E.F., et al. 1996. A novel abetalipoproteinemia genotype. Identification of a missense mutation in the 97-kDa subunit of the microsomal triglyceride transfer protein that prevents complex formation with protein disulfide isomerase. J. Biol. Chem. 271:29945-29952.
    • (1996) J. Biol. Chem. , vol.271 , pp. 29945-29952
    • Rehberg, E.F.1
  • 14
    • 0028834528 scopus 로고
    • Mutations of the microsomal triglyceride-transfer-protein gene in abetalipoproteinemia
    • Narcisi, T.M.E., et al. 1995. Mutations of the microsomal triglyceride-transfer-protein gene in abetalipoproteinemia. Am. J. Hum. Genet. 57:1298-1310.
    • (1995) Am. J. Hum. Genet. , vol.57 , pp. 1298-1310
    • Narcisi, T.M.E.1
  • 15
    • 0028330133 scopus 로고
    • The molecular basis of abetalipoproteinemia
    • Gregg, R.E., and Wetterau, J.R. 1994. The molecular basis of abetalipoproteinemia. Curr. Opin. Lipidol. 5:81-86.
    • (1994) Curr. Opin. Lipidol. , vol.5 , pp. 81-86
    • Gregg, R.E.1    Wetterau, J.R.2
  • 16
    • 0017070905 scopus 로고
    • Subcellular localization of B apoprotein of plasma lipoproteins in rat liver
    • Alexander, C.A., Hamilton, R.L., and Havel, R.J. 1976. Subcellular localization of B apoprotein of plasma lipoproteins in rat liver. J. Cell Biol. 69:241-263.
    • (1976) J. Cell Biol. , vol.69 , pp. 241-263
    • Alexander, C.A.1    Hamilton, R.L.2    Havel, R.J.3
  • 17
    • 0001558236 scopus 로고
    • Nascent VLDL assembly occurs in two steps in the endoplasmic reticulum (ER) of hepatocytes
    • F.P. Woodford, J. Davignon, and A. Sniderman, editors. Elsevier Science. Amsterdam, the Netherlands
    • Hamilton, R.L., Erickson, S.K., and Havel, R.J. 1995. Nascent VLDL assembly occurs in two steps in the endoplasmic reticulum (ER) of hepatocytes. In Atherosclerosis X. F.P. Woodford, J. Davignon, and A. Sniderman, editors. Elsevier Science. Amsterdam, the Netherlands. 414-418.
    • (1995) Atherosclerosis X , pp. 414-418
    • Hamilton, R.L.1    Erickson, S.K.2    Havel, R.J.3
  • 18
    • 0026780342 scopus 로고
    • Lipoprotein assembly. Apolipoprotein B size determines lipoprotein core circumference
    • Spring, D.J., et al. 1992. Lipoprotein assembly. Apolipoprotein B size determines lipoprotein core circumference. J. Biol. Chem. 267:14839-14845.
    • (1992) J. Biol. Chem. , vol.267 , pp. 14839-14845
    • Spring, D.J.1
  • 19
    • 0029128035 scopus 로고
    • Intracellular events in the assembly of very-low-density-lipoprotein lipids with apolipoprotein B in isolated rabbit hepatocytes
    • Cartwright, I.J., and Higgins, J.A. 1995. Intracellular events in the assembly of very-low-density-lipoprotein lipids with apolipoprotein B in isolated rabbit hepatocytes. Biochem. J. 310:897-907.
    • (1995) Biochem. J. , vol.310 , pp. 897-907
    • Cartwright, I.J.1    Higgins, J.A.2
  • 20
    • 0030066167 scopus 로고    scopus 로고
    • Biosynthesis of apolipoprotein B48-containing lipoproteins. Regulation by novel post-transcriptional mechanisms
    • Innerarity, T.L., Borén, J., Yamanaka, S., and Olofsson, S.-O. 1996. Biosynthesis of apolipoprotein B48-containing lipoproteins. Regulation by novel post-transcriptional mechanisms. J. Biol. Chem. 271:2353-2356.
    • (1996) J. Biol. Chem. , vol.271 , pp. 2353-2356
    • Innerarity, T.L.1    Borén, J.2    Yamanaka, S.3    Olofsson, S.-O.4
  • 21
    • 12644303527 scopus 로고    scopus 로고
    • Inhibition of the microsomal triglyceride transfer protein blocks the first step of apolipoprotein B lipoprotein assembly but not the addition of bulk core lipids in the second step
    • Gordon, D.A., et al. 1996. Inhibition of the microsomal triglyceride transfer protein blocks the first step of apolipoprotein B lipoprotein assembly but not the addition of bulk core lipids in the second step. J. Biol. Chem. 271:33047-33053.
    • (1996) J. Biol. Chem. , vol.271 , pp. 33047-33053
    • Gordon, D.A.1
  • 22
    • 0030936391 scopus 로고    scopus 로고
    • Investigation of the role of lipids in the assembly of very low density lipoproteins in rabbit hepatocytes
    • Cartwright, I.J., et al. 1997. Investigation of the role of lipids in the assembly of very low density lipoproteins in rabbit hepatocytes. J. Lipid Res. 38:531-545.
    • (1997) J. Lipid Res. , vol.38 , pp. 531-545
    • Cartwright, I.J.1
  • 23
    • 0031846319 scopus 로고    scopus 로고
    • Chylomicron-sized lipid particles are formed in the setting of apolipoprotein B deficiency
    • Hamilton, R.L., et al. 1998. Chylomicron-sized lipid particles are formed in the setting of apolipoprotein B deficiency. J. Lipid Res. 39:1543-1557.
    • (1998) J. Lipid Res. , vol.39 , pp. 1543-1557
    • Hamilton, R.L.1
  • 24
    • 0028036640 scopus 로고
    • Studies on the assembly of apolipoprotein B-100- and B-48-containing very low density lipoproteins in McA-RH7777 cells
    • Borén, J., Rustaeus, S., and Olofsson, S.-O. 1994. Studies on the assembly of apolipoprotein B-100- and B-48-containing very low density lipoproteins in McA-RH7777 cells. J. Biol. Chem. 269:25879-25888.
    • (1994) J. Biol. Chem. , vol.269 , pp. 25879-25888
    • Borén, J.1    Rustaeus, S.2    Olofsson, S.-O.3
  • 25
    • 0029904269 scopus 로고    scopus 로고
    • Translocation of apolipoprotein B across the endoplasmic reticulum is blocked in abetalipoproteinemia
    • Du, E.Z., et al. 1996. Translocation of apolipoprotein B across the endoplasmic reticulum is blocked in abetalipoproteinemia. J. Lipid Res. 37:1309-1315.
    • (1996) J. Lipid Res. , vol.37 , pp. 1309-1315
    • Du, E.Z.1
  • 26
    • 0029058132 scopus 로고
    • Microsomal triglyceride transfer protein: A protein complex required for the assembly of lipoprotein particles
    • Gordon, D.A., Wetterau, J.R., and Gregg, R.E. 1995. Microsomal triglyceride transfer protein: a protein complex required for the assembly of lipoprotein particles. Trends Cell Biol. 5:317-321.
    • (1995) Trends Cell Biol. , vol.5 , pp. 317-321
    • Gordon, D.A.1    Wetterau, J.R.2    Gregg, R.E.3
  • 27
    • 0030924691 scopus 로고    scopus 로고
    • Normal activity of microsomal triglyceride transfer protein is required for the oleate-induced secretion of very low density lipoproteins containing apolipoprotein B from McA-RH7777 cells
    • Wang, Y., McLeod, R.S., and Yao, Z. 1997. Normal activity of microsomal triglyceride transfer protein is required for the oleate-induced secretion of very low density lipoproteins containing apolipoprotein B from McA-RH7777 cells. J. Biol. Chem. 272:12272-12278.
    • (1997) J. Biol. Chem. , vol.272 , pp. 12272-12278
    • Wang, Y.1    McLeod, R.S.2    Yao, Z.3
  • 28
    • 0029155706 scopus 로고
    • Inducible gene targeting in mice
    • Kühn, R., Schwenk, F., Aguet, M., and Rajewsky, K. 1995. Inducible gene targeting in mice. Science. 269:1427-1429.
    • (1995) Science , vol.269 , pp. 1427-1429
    • Kühn, R.1    Schwenk, F.2    Aguet, M.3    Rajewsky, K.4
  • 29
    • 0029807339 scopus 로고    scopus 로고
    • Conditional gene targeting
    • Rajewsky, K., et al. 1996. Conditional gene targeting. J. Clin. Invest. 98:600-603.
    • (1996) J. Clin. Invest. , vol.98 , pp. 600-603
    • Rajewsky, K.1
  • 30
    • 0031443874 scopus 로고    scopus 로고
    • Protamine-Cre recombinase transgenes efficiently recombine target sequences in the male germ line of mice, but not in embryonic stem cells
    • O'Gorman, S., Dagenais, N.A., Qian, M., and Marchuk, Y. 1997. Protamine-Cre recombinase transgenes efficiently recombine target sequences in the male germ line of mice, but not in embryonic stem cells. Proc. Natl. Acad. Sci. USA. 94:14602-14607.
    • (1997) Proc. Natl. Acad. Sci. USA , vol.94 , pp. 14602-14607
    • O'Gorman, S.1    Dagenais, N.A.2    Qian, M.3    Marchuk, Y.4
  • 31
    • 0032004972 scopus 로고    scopus 로고
    • Inducible inactivation of hepatic LRP gene by Cre-mediated recombination confirms role of LRP in clearance of chylomicron remnants
    • Rohlmann, A., Gotthardt, M., Hammer, R.E., and Herz, J. 1998. Inducible inactivation of hepatic LRP gene by Cre-mediated recombination confirms role of LRP in clearance of chylomicron remnants. J. Clin. Invest. 101:689-695.
    • (1998) J. Clin. Invest. , vol.101 , pp. 689-695
    • Rohlmann, A.1    Gotthardt, M.2    Hammer, R.E.3    Herz, J.4
  • 32
    • 0029043548 scopus 로고
    • Site-specific recombination mediated by an adenovirus vector expressing the Cre recombinase protein: A molecular switch for control of gene expression
    • Anton, M., and Graham, F.L. 1995. Site-specific recombination mediated by an adenovirus vector expressing the Cre recombinase protein: a molecular switch for control of gene expression. J. Virol. 69:4600-4606.
    • (1995) J. Virol. , vol.69 , pp. 4600-4606
    • Anton, M.1    Graham, F.L.2
  • 33
    • 0029959746 scopus 로고    scopus 로고
    • Sustained somatic gene inactivation by viral transfer of Cre recombinase
    • Rohlmann, A., et al. 1996. Sustained somatic gene inactivation by viral transfer of Cre recombinase. Nat. Biotechnol. 14:1562-1565.
    • (1996) Nat. Biotechnol. , vol.14 , pp. 1562-1565
    • Rohlmann, A.1
  • 34
    • 0002025785 scopus 로고
    • Manipulation of adenovirus vectors
    • Graham, F.L., and Prevec, L. 1991. Manipulation of adenovirus vectors. Methods Mol. Biol. 7:109-128.
    • (1991) Methods Mol. Biol. , vol.7 , pp. 109-128
    • Graham, F.L.1    Prevec, L.2
  • 35
    • 0029951819 scopus 로고    scopus 로고
    • Transgenic mice that overexpress mouse apolipoprotein B. Evidence that the DNA sequences controlling intestinal expression of the apolipoprotein B gene are distant from the structural gene
    • McCormick, S.P.A., et al. 1996. Transgenic mice that overexpress mouse apolipoprotein B. Evidence that the DNA sequences controlling intestinal expression of the apolipoprotein B gene are distant from the structural gene. J. Biol. Chem. 271:11963-11970.
    • (1996) J. Biol. Chem. , vol.271 , pp. 11963-11970
    • McCormick, S.P.A.1
  • 36
    • 0027145132 scopus 로고
    • Transgenic mice expressing high plasma concentrations of human apolipoprotein B100 and lipoprotein(a)
    • Linton, M.F., et al. 1993. Transgenic mice expressing high plasma concentrations of human apolipoprotein B100 and lipoprotein(a). J. Clin. Invest. 92:3029-3037.
    • (1993) J. Clin. Invest. , vol.92 , pp. 3029-3037
    • Linton, M.F.1
  • 37
    • 0028918775 scopus 로고
    • Knockout of the mouse apolipoprotein B gene results in embryonic lethality in homozygotes and protection against diet-induced hypercholesterolemia in heterozygotes
    • Farese, R.V., Jr., et al. 1995. Knockout of the mouse apolipoprotein B gene results in embryonic lethality in homozygotes and protection against diet-induced hypercholesterolemia in heterozygotes. Proc. Natl. Acad. Sci. USA. 92:1774-1778.
    • (1995) Proc. Natl. Acad. Sci. USA , vol.92 , pp. 1774-1778
    • Farese R.V., Jr.1
  • 38
    • 0032894472 scopus 로고    scopus 로고
    • Generation of monoclonal antibodies specific for mouse apolipoprotein B-100 in apolipoprotein B-48-only mice
    • Zlot, C.H., et al. 1999. Generation of monoclonal antibodies specific for mouse apolipoprotein B-100 in apolipoprotein B-48-only mice. J. Lipid Res. 40:76-84.
    • (1999) J. Lipid Res. , vol.40 , pp. 76-84
    • Zlot, C.H.1
  • 39
    • 0032521141 scopus 로고    scopus 로고
    • Dual mechanisms for the low plasma levels of truncared apolipoprotein B proteins in familial hypobetalipoproreinemia. Analysis of a new mouse model with a nonsense mutation in the Apob gene
    • Kim, E., et al. 1998. Dual mechanisms for the low plasma levels of truncared apolipoprotein B proteins in familial hypobetalipoproreinemia. Analysis of a new mouse model with a nonsense mutation in the Apob gene. J Clin. Invest. 101:1468-1477.
    • (1998) J Clin. Invest. , vol.101 , pp. 1468-1477
    • Kim, E.1
  • 40
    • 0020431640 scopus 로고
    • Imidazole-buffered osmium tetroxide: An excellent stain for visualization of lipids in transmission electron microscopy
    • Angermüller, S., and Fahimi, H.D. 1982. Imidazole-buffered osmium tetroxide: an excellent stain for visualization of lipids in transmission electron microscopy. Histochem. J. 14:823-835.
    • (1982) Histochem. J. , vol.14 , pp. 823-835
    • Angermüller, S.1    Fahimi, H.D.2
  • 41
    • 0028821841 scopus 로고
    • A genetic model for absent chylomicron formation: Mice producing apolipoprotein B in the liver, but not in the intestine
    • Young, S.G., et al. 1995. A genetic model for absent chylomicron formation: Mice producing apolipoprotein B in the liver, but not in the intestine. J Clin. Invest. 96:2932-2946.
    • (1995) J Clin. Invest. , vol.96 , pp. 2932-2946
    • Young, S.G.1
  • 42
    • 0022558756 scopus 로고
    • In situ cDNA:mRNA hybridization: Development of a technique to measure mRNA levels in individual cells
    • Wilcox, J.N., Gee, C.E., and Roberts, J.L. 1986. In situ cDNA:mRNA hybridization: development of a technique to measure mRNA levels in individual cells. Methods Enzymol. 124:510-533.
    • (1986) Methods Enzymol. , vol.124 , pp. 510-533
    • Wilcox, J.N.1    Gee, C.E.2    Roberts, J.L.3
  • 43
    • 0019888362 scopus 로고
    • Bacteriophage P1 site-specific recombination. I. Recombination between loxP sices
    • Sternberg, N., and Hamilton, D. 1981. Bacteriophage P1 site-specific recombination. I. Recombination between loxP sices. J. Mol. Biol. 150:467-486.
    • (1981) J. Mol. Biol. , vol.150 , pp. 467-486
    • Sternberg, N.1    Hamilton, D.2
  • 44
    • 0022857828 scopus 로고
    • Analysis of the apolipoprotein B gene and messenger ribonucleic acid in abetalipoproteinemia
    • Lackner, K.J., et al. 1986. Analysis of the apolipoprotein B gene and messenger ribonucleic acid in abetalipoproteinemia. J. Clin. Invest. 78:1707-1712.
    • (1986) J. Clin. Invest. , vol.78 , pp. 1707-1712
    • Lackner, K.J.1
  • 45
    • 0025743782 scopus 로고
    • Apolipoprotein synthesis in normal and abetalipoproteinemic intestinal mucosa
    • Glickman, R.M., Glickman, J.N., Magun, A., and Brin, M. 1991. Apolipoprotein synthesis in normal and abetalipoproteinemic intestinal mucosa. Gastroenterology. 101:749-755.
    • (1991) Gastroenterology , vol.101 , pp. 749-755
    • Glickman, R.M.1    Glickman, J.N.2    Magun, A.3    Brin, M.4
  • 46
    • 0025834249 scopus 로고
    • Intestinal and hepatic apolipoprotein B gene expression in abetalipoproteinemia
    • Black, D.D., et al. 1991. Intestinal and hepatic apolipoprotein B gene expression in abetalipoproteinemia. Gastroenterology. 101:520-528.
    • (1991) Gastroenterology , vol.101 , pp. 520-528
    • Black, D.D.1
  • 47
    • 0027424646 scopus 로고
    • Chimeric-transgenic mice represent a powerful tool for studying how the proliferation and differentiation programs of intestinal epithelial cell lineages are regulated
    • Hermiston, M.L., Green, R.P., and Gordon, J.I. 1993. Chimeric-transgenic mice represent a powerful tool for studying how the proliferation and differentiation programs of intestinal epithelial cell lineages are regulated. Proc. Natl. Acad. Sci. USA. 90:8866-8870.
    • (1993) Proc. Natl. Acad. Sci. USA , vol.90 , pp. 8866-8870
    • Hermiston, M.L.1    Green, R.P.2    Gordon, J.I.3
  • 48
    • 0027200384 scopus 로고
    • Understanding gastrointestinal epithelial cell biology: Lessons from mice with help from worms and flies
    • Gordon, J.I. 1993. Understanding gastrointestinal epithelial cell biology: Lessons from mice with help from worms and flies. Gastroenterology. 104:315-324.
    • (1993) Gastroenterology , vol.104 , pp. 315-324
    • Gordon, J.I.1
  • 49
    • 0028960478 scopus 로고
    • Transgenic mice expressing high levels of human apolipoprotein B develop severe atherosclerotic lesions in response to a high-fat diet
    • Purcell-Huynh, D.A., et al. 1995. Transgenic mice expressing high levels of human apolipoprotein B develop severe atherosclerotic lesions in response to a high-fat diet. J. Clin. Invest. 95:2246-2257.
    • (1995) J. Clin. Invest. , vol.95 , pp. 2246-2257
    • Purcell-Huynh, D.A.1
  • 50
    • 0022980020 scopus 로고
    • Nascent high density lipoproteins from liver perfusates of oroticacid-fed rats
    • Hamilton, R.L., et al. 1986. Nascent high density lipoproteins from liver perfusates of oroticacid-fed rats. J. Lipid Res. 27:967-978.
    • (1986) J. Lipid Res. , vol.27 , pp. 967-978
    • Hamilton, R.L.1
  • 51
    • 0028890198 scopus 로고
    • Murine mammary-derived cells secrete the N-terminal 41% of human apolipoprotein B on high density lipoprotein-sized lipoproteins containing a triacylglycerol-rich core
    • Herscovitz, H., et al. 1995. Murine mammary-derived cells secrete the N-terminal 41% of human apolipoprotein B on high density lipoprotein-sized lipoproteins containing a triacylglycerol-rich core. Proc. Natl. Acad. Sci. USA. 92:659-663.
    • (1995) Proc. Natl. Acad. Sci. USA , vol.92 , pp. 659-663
    • Herscovitz, H.1
  • 52
    • 0031882256 scopus 로고    scopus 로고
    • Participation of the microsomal triglyceride transfer protein in lipoprotein assembly in Caco-2 cells: Interaction with saturated and unsaturated dietary fatty acids
    • van Greevenbroek, M.M.J., Robertus-Teunissen, M.G., Erkelens, D.W., and de Bruin, T.W.A. 1998. Participation of the microsomal triglyceride transfer protein in lipoprotein assembly in Caco-2 cells: interaction with saturated and unsaturated dietary fatty acids. J. Lipid Res. 39:173-185.
    • (1998) J. Lipid Res. , vol.39 , pp. 173-185
    • Van Greevenbroek, M.M.J.1    Robertus-Teunissen, M.G.2    Erkelens, D.W.3    De Bruin, T.W.A.4
  • 53
    • 0029996677 scopus 로고    scopus 로고
    • Inhibition of apolipoprotein B and triglyceride secretion in human hepatoma cells (HepG2)
    • Haghpassand, M., Wilder, D., and Moberly, J.B. 1996. Inhibition of apolipoprotein B and triglyceride secretion in human hepatoma cells (HepG2). J. Lipid Res. 37:1468-1480.
    • (1996) J. Lipid Res. , vol.37 , pp. 1468-1480
    • Haghpassand, M.1    Wilder, D.2    Moberly, J.B.3
  • 54
    • 0028128428 scopus 로고
    • Microsomal triglyceride transfer protein, the abetalipoproteinemia gene product, mediates the secretion of apolipoprotein B-containing lipoproteins from heterologous cells
    • Leiper, J.M., et al. 1994. Microsomal triglyceride transfer protein, the abetalipoproteinemia gene product, mediates the secretion of apolipoprotein B-containing lipoproteins from heterologous cells. J. Biol. Chem. 269:21951-21954.
    • (1994) J. Biol. Chem. , vol.269 , pp. 21951-21954
    • Leiper, J.M.1
  • 55
    • 0027966127 scopus 로고
    • Secretion of apolipoprotein B-containing lipoproteins from HeLa cells is dependent on expression of the microsomal triglyceride transfer protein and is regulated by lipid availability
    • Gordon, D.A., et al. 1994. Secretion of apolipoprotein B-containing lipoproteins from HeLa cells is dependent on expression of the microsomal triglyceride transfer protein and is regulated by lipid availability. Proc. Natl. Acad. Sci. USA. 91:7628-7632.
    • (1994) Proc. Natl. Acad. Sci. USA , vol.91 , pp. 7628-7632
    • Gordon, D.A.1
  • 56
    • 0029975626 scopus 로고    scopus 로고
    • The microsomal triglyceride transfer protein facilitates assembly and secretion of apolipoprotein B-containing lipoproteins and decreases cotranslational degradation of apolipoprotein B in transfected COS-7 cells
    • Wang, S., McLeod, R.S., Gordon, D.A., and Yao, Z. 1996. The microsomal triglyceride transfer protein facilitates assembly and secretion of apolipoprotein B-containing lipoproteins and decreases cotranslational degradation of apolipoprotein B in transfected COS-7 cells. J. Biol. Chem. 271:14124-14133.
    • (1996) J. Biol. Chem. , vol.271 , pp. 14124-14133
    • Wang, S.1    McLeod, R.S.2    Gordon, D.A.3    Yao, Z.4
  • 57
    • 0002495086 scopus 로고
    • Structure and metabolism of plasma lipoproteins
    • C.R. Scriver, A.L. Beaudet, W.S. Sly, and D. Valle, editors. McGraw-Hill. New York, NY
    • Havel, R.J., and Kane, J.P. 1989. Structure and metabolism of plasma lipoproteins. In The metabolic basis of inherited disease. 6th edition. C.R. Scriver, A.L. Beaudet, W.S. Sly, and D. Valle, editors. McGraw-Hill. New York, NY. 1129-1138.
    • (1989) The Metabolic Basis of Inherited Disease. 6th Edition , pp. 1129-1138
    • Havel, R.J.1    Kane, J.P.2
  • 58
    • 0025086368 scopus 로고
    • Recent progress in understanding apolipoprotein B
    • Young, S.G. 1990. Recent progress in understanding apolipoprotein B. Circulation. 82:1574-1594.
    • (1990) Circulation , vol.82 , pp. 1574-1594
    • Young, S.G.1
  • 59
    • 85010247288 scopus 로고
    • An ultrastructural study of the intestinal mucosa in congenital β-lipoprotein deficiency with particular emphasis upon the intestinal absorptive cell
    • Dobbins, W.O., III. 1966. An ultrastructural study of the intestinal mucosa in congenital β-lipoprotein deficiency with particular emphasis upon the intestinal absorptive cell. Gastroenterology. 50:195-210.
    • (1966) Gastroenterology , vol.50 , pp. 195-210
    • Dobbins W.O. III1
  • 60
    • 0027716370 scopus 로고
    • Abetalipoproteinemia is caused by defects of the gene encoding the 97 kDa subunit of a microsomal triglyceride transfer protein
    • Shoulders, C.C., et al. 1993. Abetalipoproteinemia is caused by defects of the gene encoding the 97 kDa subunit of a microsomal triglyceride transfer protein. Hum. Mol. Genet. 2:2109-2116.
    • (1993) Hum. Mol. Genet. , vol.2 , pp. 2109-2116
    • Shoulders, C.C.1
  • 61
    • 0032532670 scopus 로고    scopus 로고
    • Assessing the roles of the two receptors for lipoprotein clearance in LDL receptor-deficient "apo B-48-only" and "apoB-100-only" mice
    • Véniant, M.M., et al. 1998 Assessing the roles of the two receptors for lipoprotein clearance in LDL receptor-deficient "apo B-48-only" and "apoB-100-only" mice. J. Clin. Invest. 102:1559-1568
    • (1998) J. Clin. Invest. , vol.102 , pp. 1559-1568
    • Véniant, M.M.1
  • 62
    • 0033525712 scopus 로고    scopus 로고
    • Liver-specific inactivation of the abetalipoproteinemia gene completely abrogates very low density lipoprotein/low density lipoprotein production in a viable conditional knockout mouse
    • Chang, B.H.-J., et al. 1999. Liver-specific inactivation of the abetalipoproteinemia gene completely abrogates very low density lipoprotein/low density lipoprotein production in a viable conditional knockout mouse. J. Biol. Chem. 274:6051-6055.
    • (1999) J. Biol. Chem. , vol.274 , pp. 6051-6055
    • Chang, B.H.-J.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.