-
1
-
-
0035897696
-
Executive Summary of The Third Report of The National Cholesterol Education Program (NCEP) Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol In Adults (Adult Treatment Panel III)
-
Executive Summary of The Third Report of The National Cholesterol Education Program (NCEP) Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol In Adults (Adult Treatment Panel III). JAMA 2001;285:2486-2497.
-
(2001)
JAMA
, vol.285
, pp. 2486-2497
-
-
-
3
-
-
34247557647
-
Metabolic syndrome and gastrointestinal diseases
-
Watanabe S, Hojo M, Nagahara A. Metabolic syndrome and gastrointestinal diseases. J Gastroenterol 2007;42:267-274.
-
(2007)
J Gastroenterol
, vol.42
, pp. 267-274
-
-
Watanabe, S.1
Hojo, M.2
Nagahara, A.3
-
4
-
-
0037129380
-
Nonalcoholic fatty liver disease
-
Angulo P. Nonalcoholic fatty liver disease. N Engl J Med 2002;346:1221-1231.
-
(2002)
N Engl J Med
, vol.346
, pp. 1221-1231
-
-
Angulo, P.1
-
6
-
-
0019152816
-
Nonalcoholic steatohepatitis: Mayo Clinic experiences with a hitherto unnamed disease
-
Ludwig J, Viggiano TR, McGill DB, Oh BJ. Nonalcoholic steatohepatitis: Mayo Clinic experiences with a hitherto unnamed disease. Mayo Clin Proc 1980;55:434-438.
-
(1980)
Mayo Clin Proc
, vol.55
, pp. 434-438
-
-
Ludwig, J.1
Viggiano, T.R.2
McGill, D.B.3
Oh, B.J.4
-
7
-
-
0032697493
-
The spread of the obesity epidemic in the United States, 1991-1998
-
Mokdad AH, Serdula MK, Dietz WH, Bowman BA, Marks JS, Koplan JP. The spread of the obesity epidemic in the United States, 1991-1998. JAMA 1999;282:1519-1522.
-
(1999)
JAMA
, vol.282
, pp. 1519-1522
-
-
Mokdad, A.H.1
Serdula, M.K.2
Dietz, W.H.3
Bowman, B.A.4
Marks, J.S.5
Koplan, J.P.6
-
8
-
-
0035850402
-
The continuing epidemics of obesity and diabetes in the United States
-
Mokdad AH, Bowman BA, Ford ES, Vinicor F, Marks JS, Koplan JP. The continuing epidemics of obesity and diabetes in the United States. JAMA 2001;286:1195-1200.
-
(2001)
JAMA
, vol.286
, pp. 1195-1200
-
-
Mokdad, A.H.1
Bowman, B.A.2
Ford, E.S.3
Vinicor, F.4
Marks, J.S.5
Koplan, J.P.6
-
9
-
-
0035431018
-
Nonalcoholic fatty liver disease: A feature of the metabolic syndrome
-
Marchesini G, Brizi M, Bianchi G, Tomassetti S, Bugianesi E, Lenzi M, et al. Nonalcoholic fatty liver disease: A feature of the metabolic syndrome. Diabetes 2001;50:1844-1850.
-
(2001)
Diabetes
, vol.50
, pp. 1844-1850
-
-
Marchesini, G.1
Brizi, M.2
Bianchi, G.3
Tomassetti, S.4
Bugianesi, E.5
Lenzi, M.6
-
10
-
-
18244385511
-
Nonalcoholic steatohepatitis, insulin resistance, and metabolic syndrome: Further evidence for an etiologic association
-
Pagano G, Pacini G, Musso G, Gambino R, Mecca F, Depetris N, et al. Nonalcoholic steatohepatitis, insulin resistance, and metabolic syndrome: Further evidence for an etiologic association. Hepatology 2002;35:367-372.
-
(2002)
Hepatology
, vol.35
, pp. 367-372
-
-
Pagano, G.1
Pacini, G.2
Musso, G.3
Gambino, R.4
Mecca, F.5
Depetris, N.6
-
11
-
-
0037382786
-
Nonalcoholic fatty liver, steatohepatitis, and the metabolic syndrome
-
Marchesini G, Bugianesi E, Forlani G, Cerrelli F, Lenzi M, Manini R, et al. Nonalcoholic fatty liver, steatohepatitis, and the metabolic syndrome. Hepatology 2003;37:917-923.
-
(2003)
Hepatology
, vol.37
, pp. 917-923
-
-
Marchesini, G.1
Bugianesi, E.2
Forlani, G.3
Cerrelli, F.4
Lenzi, M.5
Manini, R.6
-
12
-
-
0031947715
-
Steatohepatitis: A tale of two "hits"?
-
Day CP, James OF. Steatohepatitis: A tale of two "hits"? Gastroenterology 1998;114:842-845.
-
(1998)
Gastroenterology
, vol.114
, pp. 842-845
-
-
Day, C.P.1
James, O.F.2
-
13
-
-
0033200054
-
Nonalcoholic steatohepatitis: A proposal for grading and staging the histological lesions
-
Brunt EM, Janney CG, Di Bisceglie AM, Neuschwander-Tetri BA, Bacon BR. Nonalcoholic steatohepatitis: A proposal for grading and staging the histological lesions. Am J Gastroenterol 1999;94:2467-2474.
-
(1999)
Am J Gastroenterol
, vol.94
, pp. 2467-2474
-
-
Brunt, E.M.1
Janney, C.G.2
Di Bisceglie, A.M.3
Neuschwander-Tetri, B.A.4
Bacon, B.R.5
-
14
-
-
0033038672
-
Nonalcoholic fatty liver disease: A spectrum of clinical and pathological severity
-
Matteoni CA, Younossi ZM, Gramlich T, Boparai N, Liu YC, McCullough AJ. Nonalcoholic fatty liver disease: A spectrum of clinical and pathological severity. Gastroenterology 1999;116:1413-1419.
-
(1999)
Gastroenterology
, vol.116
, pp. 1413-1419
-
-
Matteoni, C.A.1
Younossi, Z.M.2
Gramlich, T.3
Boparai, N.4
Liu, Y.C.5
McCullough, A.J.6
-
15
-
-
0038644536
-
Nonalcoholic steatohepatitis: Summary of an AASLD Single Topic Conference
-
Neuschwander-Tetri BA, Caldwell SH. Nonalcoholic steatohepatitis: summary of an AASLD Single Topic Conference. Hepatology 2003;37:1202-1219.
-
(2003)
Hepatology
, vol.37
, pp. 1202-1219
-
-
Neuschwander-Tetri, B.A.1
Caldwell, S.H.2
-
16
-
-
20044374023
-
Design and validation of a histological scoring system for nonalcoholic fatty liver disease
-
Kleiner DE, Brunt EM, Van Natta M, Behling C, Contos MJ, Cummings OW, et al. Design and validation of a histological scoring system for nonalcoholic fatty liver disease. Hepatology 2005;41:1313-1321.
-
(2005)
Hepatology
, vol.41
, pp. 1313-1321
-
-
Kleiner, D.E.1
Brunt, E.M.2
Van Natta, M.3
Behling, C.4
Contos, M.J.5
Cummings, O.W.6
-
17
-
-
10644220306
-
Prevalence of hepatic steatosis in an urban population in the United States: Impact of ethnicity
-
Browning JD, Szczepaniak LS, Dobbins R, Nuremberg P, Horton JD, Cohen JC, et al. Prevalence of hepatic steatosis in an urban population in the United States: Impact of ethnicity. Hepatology 2004;40:1387-1395.
-
(2004)
Hepatology
, vol.40
, pp. 1387-1395
-
-
Browning, J.D.1
Szczepaniak, L.S.2
Dobbins, R.3
Nuremberg, P.4
Horton, J.D.5
Cohen, J.C.6
-
18
-
-
22344452893
-
The natural history of nonalcoholic fatty liver disease: A population-based cohort study
-
Adams LA, Lymp JF, St Sauver J, Sanderson SO, Lindor KD, Feldstein A, et al. The natural history of nonalcoholic fatty liver disease: A population-based cohort study. Gastroenterology 2005;129:113-121.
-
(2005)
Gastroenterology
, vol.129
, pp. 113-121
-
-
Adams, L.A.1
Lymp, J.F.2
St Sauver, J.3
Sanderson, S.O.4
Lindor, K.D.5
Feldstein, A.6
-
19
-
-
0025178612
-
The natural history of nonalcoholic steatohepatitis: A follow-up study of forty-two patients for up to 21 years
-
Powell EE, Cooksley WG, Hanson R, Searle J, Halliday JW, Powell LW. The natural history of nonalcoholic steatohepatitis: A follow-up study of forty-two patients for up to 21 years. Hepatology 1990;11:74-80.
-
(1990)
Hepatology
, vol.11
, pp. 74-80
-
-
Powell, E.E.1
Cooksley, W.G.2
Hanson, R.3
Searle, J.4
Halliday, J.W.5
Powell, L.W.6
-
21
-
-
0028875908
-
The natural history of nonalcoholic fatty liver: A follow-up study
-
Teli MR, James OF, Burt AD, Bennett MK, Day CP. The natural history of nonalcoholic fatty liver: A follow-up study. Hepatology 1995;22:1714-1719.
-
(1995)
Hepatology
, vol.22
, pp. 1714-1719
-
-
Teli, M.R.1
James, O.F.2
Burt, A.D.3
Bennett, M.K.4
Day, C.P.5
-
22
-
-
33644547706
-
Nonalcoholic fatty liver disease: From steatosis to cirrhosis
-
Farrell GC, Larter CZ. Nonalcoholic fatty liver disease: From steatosis to cirrhosis. Hepatology 2006;43:S99-S112.
-
(2006)
Hepatology
, vol.43
-
-
Farrell, G.C.1
Larter, C.Z.2
-
23
-
-
28044446543
-
The metabolic syndrome as a predictor of nonalcoholic fatty liver disease
-
Hamaguchi M, Kojima T, Takeda N, Nakagawa T, Taniguchi H, Fujii K, et al. The metabolic syndrome as a predictor of nonalcoholic fatty liver disease. Ann Intern Med 2005;143:722-728.
-
(2005)
Ann Intern Med
, vol.143
, pp. 722-728
-
-
Hamaguchi, M.1
Kojima, T.2
Takeda, N.3
Nakagawa, T.4
Taniguchi, H.5
Fujii, K.6
-
24
-
-
0038606277
-
High dietary fat promotes syndrome X in nonobese rats
-
Axen KV, Dikeakos A, Sclafani A. High dietary fat promotes syndrome X in nonobese rats. J Nutr 2003;133:2244-2249.
-
(2003)
J Nutr
, vol.133
, pp. 2244-2249
-
-
Axen, K.V.1
Dikeakos, A.2
Sclafani, A.3
-
25
-
-
0026534940
-
Development of dietary obesity in rats: Influence of amount and composition of dietary fat
-
Hill JO, Lin D, Yakubu F, Peters JC. Development of dietary obesity in rats: Influence of amount and composition of dietary fat. Int J Obes Relat Metab Disord 1992;16:321-333.
-
(1992)
Int J Obes Relat Metab Disord
, vol.16
, pp. 321-333
-
-
Hill, J.O.1
Lin, D.2
Yakubu, F.3
Peters, J.C.4
-
26
-
-
11244348954
-
A high-fat diet leads to the progression of non-alcoholic fatty liver disease in obese rats
-
Carmiel-Haggai M, Cederbaum AI, Nieto N. A high-fat diet leads to the progression of non-alcoholic fatty liver disease in obese rats. FASEB J 2005;19:136-138.
-
(2005)
FASEB J
, vol.19
, pp. 136-138
-
-
Carmiel-Haggai, M.1
Cederbaum, A.I.2
Nieto, N.3
-
27
-
-
0028139089
-
Positional cloning of the mouse obese gene and its human homologue
-
Zhang Y, Proenca R, Maffei M, Barone M, Leopold L, Friedman JM. Positional cloning of the mouse obese gene and its human homologue. Nature (Lond) 1994;372:425-432.
-
(1994)
Nature (Lond)
, vol.372
, pp. 425-432
-
-
Zhang, Y.1
Proenca, R.2
Maffei, M.3
Barone, M.4
Leopold, L.5
Friedman, J.M.6
-
28
-
-
0030039272
-
Abnormal splicing of the leptin receptor in diabetic mice
-
Lee GH, Proenca R, Montez JM, Carroll KM, Darvishzadeh JG, Lee JI, et al. Abnormal splicing of the leptin receptor in diabetic mice. Nature (Lond) 1996;379:632-635.
-
(1996)
Nature (Lond)
, vol.379
, pp. 632-635
-
-
Lee, G.H.1
Proenca, R.2
Montez, J.M.3
Carroll, K.M.4
Darvishzadeh, J.G.5
Lee, J.I.6
-
29
-
-
13344259300
-
Evidence that the diabetes gene encodes the leptin receptor: Identification of a mutation in the leptin receptor gene in db/db mice
-
Chen H, Charlat O, Tartaglia LA, Woolf EA, Weng X, Ellis SJ, et al. Evidence that the diabetes gene encodes the leptin receptor: identification of a mutation in the leptin receptor gene in db/db mice. Cell 1996;84:491-495.
-
(1996)
Cell
, vol.84
, pp. 491-495
-
-
Chen, H.1
Charlat, O.2
Tartaglia, L.A.3
Woolf, E.A.4
Weng, X.5
Ellis, S.J.6
-
30
-
-
0030570741
-
Molecular cloning of rat leptin receptor isoform complementary DNAs: Identification of a missense mutation in Zucker fatty (fa/fa) rats
-
Takaya K, Ogawa Y, Isse N, Okazaki T, Satoh N, Masuzaki H, et al. Molecular cloning of rat leptin receptor isoform complementary DNAs: identification of a missense mutation in Zucker fatty (fa/fa) rats. Biochem Biophys Res Commun 1996;225:75-83.
-
(1996)
Biochem Biophys Res Commun
, vol.225
, pp. 75-83
-
-
Takaya, K.1
Ogawa, Y.2
Isse, N.3
Okazaki, T.4
Satoh, N.5
Masuzaki, H.6
-
31
-
-
18244364864
-
NASH and insulin resistance: Insulin hypersecretion and specific association with the insulin resistance syndrome
-
Chitturi S, Abeygunasekera S, Farrell GC, Holmes-Walker J, Hui JM, Fung C, et al. NASH and insulin resistance: Insulin hypersecretion and specific association with the insulin resistance syndrome. Hepatology 2002;35:373-379.
-
(2002)
Hepatology
, vol.35
, pp. 373-379
-
-
Chitturi, S.1
Abeygunasekera, S.2
Farrell, G.C.3
Holmes-Walker, J.4
Hui, J.M.5
Fung, C.6
-
32
-
-
0033562693
-
Non-alcoholic steatohepatitis: Another disease of affluence
-
James O, Day C. Non-alcoholic steatohepatitis: Another disease of affluence. Lancet 1999;353:1634-1636.
-
(1999)
Lancet
, vol.353
, pp. 1634-1636
-
-
James, O.1
Day, C.2
-
34
-
-
33748111665
-
Nonalcoholic fatty liver disease: Cytokine-adipokine interplay and regulation of insulin resistance
-
Tilg H, Hotamisligil GS. Nonalcoholic fatty liver disease: Cytokine-adipokine interplay and regulation of insulin resistance. Gastroenterology 2006;131:934-945.
-
(2006)
Gastroenterology
, vol.131
, pp. 934-945
-
-
Tilg, H.1
Hotamisligil, G.S.2
-
35
-
-
0027459878
-
Adipose expression of tumor necrosis factor-alpha: Direct role in obesity-linked insulin resistance
-
Hotamisligil GS, Shargill NS, Spiegelman BM. Adipose expression of tumor necrosis factor-alpha: Direct role in obesity-linked insulin resistance. Science 1993;259:87-91.
-
(1993)
Science
, vol.259
, pp. 87-91
-
-
Hotamisligil, G.S.1
Shargill, N.S.2
Spiegelman, B.M.3
-
36
-
-
0035183475
-
Gene expression of tumor necrosis factor alpha and TNF-receptors, p55 and p75, in nonalcoholic steatohepatitis patients
-
Crespo J, Cayon A, Fernandez-Gil P, Hernandez-Guerra M, Mayorga M, Dominguez-Diez A, et al. Gene expression of tumor necrosis factor alpha and TNF-receptors, p55 and p75, in nonalcoholic steatohepatitis patients. Hepatology 2001;34:1158-1163.
-
(2001)
Hepatology
, vol.34
, pp. 1158-1163
-
-
Crespo, J.1
Cayon, A.2
Fernandez-Gil, P.3
Hernandez-Guerra, M.4
Mayorga, M.5
Dominguez-Diez, A.6
-
37
-
-
3042824524
-
Free fatty acids promote hepatic lipotoxicity by stimulating TNF-alpha expression via a lysosomal pathway
-
Feldstein AE, Werneburg NW, Canbay A, Guicciardi ME, Bronk SF, Rydzewski R, et al. Free fatty acids promote hepatic lipotoxicity by stimulating TNF-alpha expression via a lysosomal pathway. Hepatology 2004;40:185-194.
-
(2004)
Hepatology
, vol.40
, pp. 185-194
-
-
Feldstein, A.E.1
Werneburg, N.W.2
Canbay, A.3
Guicciardi, M.E.4
Bronk, S.F.5
Rydzewski, R.6
-
38
-
-
0037309589
-
Probiotics and antibodies to TNF inhibit inflammatory activity and improve nonalcoholic fatty liver disease
-
Li Z, Yang S, Lin H, Huang J, Watkins PA, Moser AB, et al. Probiotics and antibodies to TNF inhibit inflammatory activity and improve nonalcoholic fatty liver disease. Hepatology 2003;37:343-350.
-
(2003)
Hepatology
, vol.37
, pp. 343-350
-
-
Li, Z.1
Yang, S.2
Lin, H.3
Huang, J.4
Watkins, P.A.5
Moser, A.B.6
-
39
-
-
0033515761
-
Paradoxical decrease of an adipose-specific protein, adiponectin, in obesity
-
Arita Y, Kihara S, Ouchi N, Takahashi M, Maeda K, Miyagawa J, et al. Paradoxical decrease of an adipose-specific protein, adiponectin, in obesity. Biochem Biophys Res Commun 1999;257:79-83.
-
(1999)
Biochem Biophys Res Commun
, vol.257
, pp. 79-83
-
-
Arita, Y.1
Kihara, S.2
Ouchi, N.3
Takahashi, M.4
Maeda, K.5
Miyagawa, J.6
-
40
-
-
0037135523
-
Disruption of adiponectin causes insulin resistance and neointimal formation
-
Kubota N, Terauchi Y, Yamauchi T, Kubota T, Moroi M, Matsui J, et al. Disruption of adiponectin causes insulin resistance and neointimal formation. J Biol Chem 2002;277:25863-25866.
-
(2002)
J Biol Chem
, vol.277
, pp. 25863-25866
-
-
Kubota, N.1
Terauchi, Y.2
Yamauchi, T.3
Kubota, T.4
Moroi, M.5
Matsui, J.6
-
41
-
-
0037231459
-
Association of hypoadiponectinemia with coronary artery disease in men
-
Kumada M, Kihara S, Sumitsuji S, Kawamoto T, Matsumoto S, Ouchi N, et al. Association of hypoadiponectinemia with coronary artery disease in men. Arterioscler Thromb Vasc Biol 2003;23:85-89.
-
(2003)
Arterioscler Thromb Vasc Biol
, vol.23
, pp. 85-89
-
-
Kumada, M.1
Kihara, S.2
Sumitsuji, S.3
Kawamoto, T.4
Matsumoto, S.5
Ouchi, N.6
-
42
-
-
3042744737
-
Beyond insulin resistance in NASH: TNF-alpha or adiponectin?
-
Hui JM, Hodge A, Farrell GC, Kench JG, Kriketos A, George J. Beyond insulin resistance in NASH: TNF-alpha or adiponectin? Hepatology 2004;40:46-54.
-
(2004)
Hepatology
, vol.40
, pp. 46-54
-
-
Hui, J.M.1
Hodge, A.2
Farrell, G.C.3
Kench, J.G.4
Kriketos, A.5
George, J.6
-
43
-
-
0036063777
-
Diet-induced insulin resistance in mice lacking adiponectin/ACRP30
-
Maeda N, Shimomura I, Kishida K, Nishizawa H, Matsuda M, Nagaretani H, et al. Diet-induced insulin resistance in mice lacking adiponectin/ ACRP30. Nat Med 2002;8:731-737.
-
(2002)
Nat Med
, vol.8
, pp. 731-737
-
-
Maeda, N.1
Shimomura, I.2
Kishida, K.3
Nishizawa, H.4
Matsuda, M.5
Nagaretani, H.6
-
44
-
-
0041302377
-
The fat-derived hormone adiponectin alleviates alcoholic and nonalcoholic fatty liver diseases in mice
-
Xu A, Wang Y, Keshaw H, Xu LY, Lam KS, Cooper GJ. The fat-derived hormone adiponectin alleviates alcoholic and nonalcoholic fatty liver diseases in mice. J Clin Invest 2003;112:91-100.
-
(2003)
J Clin Invest
, vol.112
, pp. 91-100
-
-
Xu, A.1
Wang, Y.2
Keshaw, H.3
Xu, L.Y.4
Lam, K.S.5
Cooper, G.J.6
-
45
-
-
2442654859
-
Identification and expression cloning of a leptin receptor, OB-R
-
Tartaglia LA, Dembski M, Weng X, Deng N, Culpepper J, Devos R, et al. Identification and expression cloning of a leptin receptor, OB-R. Cell 1995;83:1263-1271.
-
(1995)
Cell
, vol.83
, pp. 1263-1271
-
-
Tartaglia, L.A.1
Dembski, M.2
Weng, X.3
Deng, N.4
Culpepper, J.5
Devos, R.6
-
46
-
-
0032489223
-
Transdifferentiation of rat hepatic stellate cells results in leptin expression
-
Potter JJ, Womack L, Mezey E, Anania FA. Transdifferentiation of rat hepatic stellate cells results in leptin expression. Biochem Biophys Res Commun 1998;244:178-182.
-
(1998)
Biochem Biophys Res Commun
, vol.244
, pp. 178-182
-
-
Potter, J.J.1
Womack, L.2
Mezey, E.3
Anania, F.A.4
-
47
-
-
0034927064
-
Leptin augments inflammatory and profibrogenic responses in the murine liver induced by hepatotoxic chemicals
-
Ikejima K, Honda H, Yoshikawa M, Hirose M, Kitamura T, Takei Y, et al. Leptin augments inflammatory and profibrogenic responses in the murine liver induced by hepatotoxic chemicals. Hepatology 2001;34:288-297.
-
(2001)
Hepatology
, vol.34
, pp. 288-297
-
-
Ikejima, K.1
Honda, H.2
Yoshikawa, M.3
Hirose, M.4
Kitamura, T.5
Takei, Y.6
-
48
-
-
0036288668
-
Leptin is required for fibrogenic responses induced by thioacetamide in the murine liver
-
Honda H, Ikejima K, Hirose M, Yoshikawa M, Lang T, Enomoto N, et al. Leptin is required for fibrogenic responses induced by thioacetamide in the murine liver. Hepatology 2002;36:12-21.
-
(2002)
Hepatology
, vol.36
, pp. 12-21
-
-
Honda, H.1
Ikejima, K.2
Hirose, M.3
Yoshikawa, M.4
Lang, T.5
Enomoto, N.6
-
49
-
-
0036022846
-
Leptin is essential for the hepatic fibrogenic response to chronic liver injury
-
Leclercq IA, Farrell GC, Schriemer R, Robertson GR. Leptin is essential for the hepatic fibrogenic response to chronic liver injury. J Hepatol 2002;37:206-213.
-
(2002)
J Hepatol
, vol.37
, pp. 206-213
-
-
Leclercq, I.A.1
Farrell, G.C.2
Schriemer, R.3
Robertson, G.R.4
-
50
-
-
0036234147
-
Leptin receptor-mediated signaling regulates hepatic fibrogenesis and remodeling of extracellular matrix in the rat
-
Ikejima K, Takei Y, Honda H, Hirose M, Yoshikawa M, Zhang YJ, et al. Leptin receptor-mediated signaling regulates hepatic fibrogenesis and remodeling of extracellular matrix in the rat. Gastroenterology 2002;122:1399-1410.
-
(2002)
Gastroenterology
, vol.122
, pp. 1399-1410
-
-
Ikejima, K.1
Takei, Y.2
Honda, H.3
Hirose, M.4
Yoshikawa, M.5
Zhang, Y.J.6
-
51
-
-
29144492714
-
The role of leptin in progression of non-alcoholic fatty liver disease
-
Ikejima K, Okumura K, Lang T, Honda H, Abe W, Yamashina S, et al. The role of leptin in progression of non-alcoholic fatty liver disease. Hepatol Res 2005;33:151-154.
-
(2005)
Hepatol Res
, vol.33
, pp. 151-154
-
-
Ikejima, K.1
Okumura, K.2
Lang, T.3
Honda, H.4
Abe, W.5
Yamashina, S.6
-
52
-
-
0036204924
-
Leptin in hepatic fibrosis: Evidence for increased collagen production in stellate cells and lean littermates of ob/ob mice
-
Saxena NK, Ikeda K, Rockey DC, Friedman SL, Anania FA. Leptin in hepatic fibrosis: Evidence for increased collagen production in stellate cells and lean littermates of ob/ob mice. Hepatology 2002;35:762-771.
-
(2002)
Hepatology
, vol.35
, pp. 762-771
-
-
Saxena, N.K.1
Ikeda, K.2
Rockey, D.C.3
Friedman, S.L.4
Anania, F.A.5
-
53
-
-
0038644530
-
Leptin induces increased alpha2(I) collagen gene expression in cultured rat hepatic stellate cells
-
Saxena NK, Saliba G, Floyd JJ, Anania FA. Leptin induces increased alpha2(I) collagen gene expression in cultured rat hepatic stellate cells. J Cell Biochem 2003;89:311-320.
-
(2003)
J Cell Biochem
, vol.89
, pp. 311-320
-
-
Saxena, N.K.1
Saliba, G.2
Floyd, J.J.3
Anania, F.A.4
-
54
-
-
30044443872
-
Leptin enhances alpha1(I) collagen gene expression in LX-2 human hepatic stellate cells through JAK-mediated H2O2-dependent MAPK pathways
-
Cao Q, Mak KM, Lieber CS. Leptin enhances alpha1(I) collagen gene expression in LX-2 human hepatic stellate cells through JAK-mediated H2O2-dependent MAPK pathways. J Cell Biochem 2006;97:188-197.
-
(2006)
J Cell Biochem
, vol.97
, pp. 188-197
-
-
Cao, Q.1
Mak, K.M.2
Lieber, C.S.3
-
55
-
-
1042289785
-
Leptin stimulates tissue inhibitor of metalloproteinase-1 in human hepatic stellate cells: Respective roles of the JAK/STAT and JAK-mediated H2O2-dependant MAPK pathways
-
Cao Q, Mak KM, Ren C, Lieber CS. Leptin stimulates tissue inhibitor of metalloproteinase-1 in human hepatic stellate cells: Respective roles of the JAK/STAT and JAK-mediated H2O2-dependant MAPK pathways. J Biol Chem 2004;279:4292-4304.
-
(2004)
J Biol Chem
, vol.279
, pp. 4292-4304
-
-
Cao, Q.1
Mak, K.M.2
Ren, C.3
Lieber, C.S.4
-
56
-
-
33751516706
-
Leptin increases tissue inhibitor of metalloproteinase I (TIMP-1) gene expression by a specificity protein 1/signal transducer and activator of transcription 3 mechanism
-
Lin S, Saxena NK, Ding X, Stein LL, Anania FA. Leptin increases tissue inhibitor of metalloproteinase I (TIMP-1) gene expression by a specificity protein 1/signal transducer and activator of transcription 3 mechanism. Mol Endocrinol 2006;20:3376-3388.
-
(2006)
Mol Endocrinol
, vol.20
, pp. 3376-3388
-
-
Lin, S.1
Saxena, N.K.2
Ding, X.3
Stein, L.L.4
Anania, F.A.5
-
57
-
-
34548162930
-
Leptin represses matrix metalloproteinase-1 gene expression in LX2 human hepatic stellate cells
-
Cao Q, Mak KM, Lieber CS. Leptin represses matrix metalloproteinase-1 gene expression in LX2 human hepatic stellate cells. J Hepatol 2007;46:124-133.
-
(2007)
J Hepatol
, vol.46
, pp. 124-133
-
-
Cao, Q.1
Mak, K.M.2
Lieber, C.S.3
-
58
-
-
32944478021
-
Upregulation of proinflammatory and proangiogenic cytokines by leptin in human hepatic stellate cells
-
Aleffi S, Petrai I, Bertolani C, Parola M, Colombatto S, Novo E, et al. Upregulation of proinflammatory and proangiogenic cytokines by leptin in human hepatic stellate cells. Hepatology 2005;42:1339-1348.
-
(2005)
Hepatology
, vol.42
, pp. 1339-1348
-
-
Aleffi, S.1
Petrai, I.2
Bertolani, C.3
Parola, M.4
Colombatto, S.5
Novo, E.6
-
59
-
-
0035084699
-
Nonalcoholic steatohepatitis: Association of insulin resistance and mitochondrial abnormalities
-
Sanyal AJ, Campbell-Sargent C, Mirshahi F, Rizzo WB, Contos MJ, Sterling RK, et al. Nonalcoholic steatohepatitis: Association of insulin resistance and mitochondrial abnormalities. Gastroenterology 2001;120:1183-1192.
-
(2001)
Gastroenterology
, vol.120
, pp. 1183-1192
-
-
Sanyal, A.J.1
Campbell-Sargent, C.2
Mirshahi, F.3
Rizzo, W.B.4
Contos, M.J.5
Sterling, R.K.6
-
60
-
-
0033198978
-
Mitochondrial abnormalities in nonalcoholic steatohepatitis
-
Caldwell SH, Swerdlow RH, Khan EM, Iezzoni JC, Hespenheide EE, Parks JK, et al. Mitochondrial abnormalities in nonalcoholic steatohepatitis. J Hepatol 1999;31:430-434.
-
(1999)
J Hepatol
, vol.31
, pp. 430-434
-
-
Caldwell, S.H.1
Swerdlow, R.H.2
Khan, E.M.3
Iezzoni, J.C.4
Hespenheide, E.E.5
Parks, J.K.6
-
61
-
-
12344305124
-
Mitochondrial dysfunction and type 2 diabetes
-
Lowell BB, Shulman GI. Mitochondrial dysfunction and type 2 diabetes. Science 2005;307:384-387.
-
(2005)
Science
, vol.307
, pp. 384-387
-
-
Lowell, B.B.1
Shulman, G.I.2
-
62
-
-
33748946183
-
Uric acid and anti-TNF antibody improve mitochondrial dysfunction in ob/ ob mice
-
Garcia-Ruiz I, Rodriguez-Juan C, Diaz-Sanjuan T, del Hoyo P, Colina F, Munoz-Yague T, et al. Uric acid and anti-TNF antibody improve mitochondrial dysfunction in ob/ob mice. Hepatology 2006;44:581-591.
-
(2006)
Hepatology
, vol.44
, pp. 581-591
-
-
Garcia-Ruiz, I.1
Rodriguez-Juan, C.2
Diaz-Sanjuan, T.3
del Hoyo, P.4
Colina, F.5
Munoz-Yague, T.6
-
63
-
-
0036829816
-
Natural history of chronic hepatitis C
-
Seeff LB. Natural history of chronic hepatitis C. Hepatology 2002;36:S35-46.
-
(2002)
Hepatology
, vol.36
-
-
Seeff, L.B.1
-
64
-
-
0037179698
-
Peginterferon alfa-2a plus ribavirin for chronic hepatitis C virus infection
-
Fried MW, Shiffman ML, Reddy KR, Smith C, Marinos G, Goncales FL Jr, et al. Peginterferon alfa-2a plus ribavirin for chronic hepatitis C virus infection. N Engl J Med 2002;347:975-982.
-
(2002)
N Engl J Med
, vol.347
, pp. 975-982
-
-
Fried, M.W.1
Shiffman, M.L.2
Reddy, K.R.3
Smith, C.4
Marinos, G.5
Goncales Jr., F.L.6
-
65
-
-
1542378867
-
Peginterferon-alpha2a and ribavirin combination therapy in chronic hepatitis C: A randomized study of treatment duration and ribavirin dose
-
Hadziyannis SJ, Sette H, Jr., Morgan TR, Balan V, Diago M, Marcellin P, et al. Peginterferon-alpha2a and ribavirin combination therapy in chronic hepatitis C: A randomized study of treatment duration and ribavirin dose. Ann Intern Med 2004;140:346-355.
-
(2004)
Ann Intern Med
, vol.140
, pp. 346-355
-
-
Hadziyannis, S.J.1
Sette Jr., H.2
Morgan, T.R.3
Balan, V.4
Diago, M.5
Marcellin, P.6
-
66
-
-
0035934568
-
Peginterferon alfa-2b plus ribavirin compared with interferon alfa-2b plus ribavirin for initial treatment of chronic hepatitis C: A randomised trial
-
Manns MP, McHutchison JG, Gordon SC, Rustgi VK, Shiffman M, Reindollar R, et al. Peginterferon alfa-2b plus ribavirin compared with interferon alfa-2b plus ribavirin for initial treatment of chronic hepatitis C: A randomised trial. Lancet 2001;358:958-965.
-
(2001)
Lancet
, vol.358
, pp. 958-965
-
-
Manns, M.P.1
McHutchison, J.G.2
Gordon, S.C.3
Rustgi, V.K.4
Shiffman, M.5
Reindollar, R.6
-
67
-
-
11144225924
-
Hepatitis C and nonalcoholic fatty liver disease
-
Ramesh S, Sanyal AJ. Hepatitis C and nonalcoholic fatty liver disease. Semin Liver Dis 2004;24:399-413.
-
(2004)
Semin Liver Dis
, vol.24
, pp. 399-413
-
-
Ramesh, S.1
Sanyal, A.J.2
-
68
-
-
0842300373
-
Steatosis and hepatitis C virus: Mechanisms and significance for hepatic and extrahepatic disease
-
Lonardo A, Adinolfi LE, Loria P, Carulli N, Ruggiero G, Day CP. Steatosis and hepatitis C virus: Mechanisms and significance for hepatic and extrahepatic disease. Gastroenterology 2004;126:586-597.
-
(2004)
Gastroenterology
, vol.126
, pp. 586-597
-
-
Lonardo, A.1
Adinolfi, L.E.2
Loria, P.3
Carulli, N.4
Ruggiero, G.5
Day, C.P.6
-
69
-
-
0346874154
-
In overweight patients with chronic hepatitis C, circulating insulin is associated with hepatic fibrosis: Implications for therapy
-
Hickman IJ, Powell EE, Prins JB, Clouston AD, Ash S, Purdie DM, et al. In overweight patients with chronic hepatitis C, circulating insulin is associated with hepatic fibrosis: Implications for therapy. J Hepatol 2003;39:1042-1048.
-
(2003)
J Hepatol
, vol.39
, pp. 1042-1048
-
-
Hickman, I.J.1
Powell, E.E.2
Prins, J.B.3
Clouston, A.D.4
Ash, S.5
Purdie, D.M.6
-
70
-
-
0036727323
-
Steatosis in chronic hepatitis C: Relative contributions of obesity, diabetes mellitus, and alcohol
-
Monto A, Alonzo J, Watson JJ, Grunfeld C, Wright TL. Steatosis in chronic hepatitis C: Relative contributions of obesity, diabetes mellitus, and alcohol. Hepatology 2002;36:729-736.
-
(2002)
Hepatology
, vol.36
, pp. 729-736
-
-
Monto, A.1
Alonzo, J.2
Watson, J.J.3
Grunfeld, C.4
Wright, T.L.5
-
71
-
-
33644806684
-
Insulin resistance is associated with steatosis in nondiabetic patients with genotype 1 chronic hepatitis C
-
Camma C, Bruno S, Di Marco V, Di Bona D, Rumi M, Vinci M, et al. Insulin resistance is associated with steatosis in nondiabetic patients with genotype 1 chronic hepatitis C. Hepatology 2006;43:64-71.
-
(2006)
Hepatology
, vol.43
, pp. 64-71
-
-
Camma, C.1
Bruno, S.2
Di Marco, V.3
Di Bona, D.4
Rumi, M.5
Vinci, M.6
-
72
-
-
33846463006
-
Race, insulin resistance and hepatic steatosis in chronic hepatitis C
-
Conjeevaram HS, Kleiner DE, Everhart JE, Hoofnagle JH, Zacks S, Afdhal NH, et al. Race, insulin resistance and hepatic steatosis in chronic hepatitis C. Hepatology 2007;45:80-87.
-
(2007)
Hepatology
, vol.45
, pp. 80-87
-
-
Conjeevaram, H.S.1
Kleiner, D.E.2
Everhart, J.E.3
Hoofnagle, J.H.4
Zacks, S.5
Afdhal, N.H.6
-
73
-
-
0033933140
-
Hepatocyte steatosis is a cytopathic effect of hepatitis C virus genotype 3
-
Rubbia-Brandt L, Quadri R, Abid K, Giostra E, Male PJ, Mentha G, et al. Hepatocyte steatosis is a cytopathic effect of hepatitis C virus genotype 3. J Hepatol 2000;33:106-115.
-
(2000)
J Hepatol
, vol.33
, pp. 106-115
-
-
Rubbia-Brandt, L.1
Quadri, R.2
Abid, K.3
Giostra, E.4
Male, P.J.5
Mentha, G.6
-
74
-
-
10744227418
-
The impact of steatosis on disease progression and early and sustained treatment response in chronic hepatitis C patients
-
Patton HM, Patel K, Behling C, Bylund D, Blatt LM, Vallee M, et al. The impact of steatosis on disease progression and early and sustained treatment response in chronic hepatitis C patients. J Hepatol 2004;40:484-490.
-
(2004)
J Hepatol
, vol.40
, pp. 484-490
-
-
Patton, H.M.1
Patel, K.2
Behling, C.3
Bylund, D.4
Blatt, L.M.5
Vallee, M.6
-
75
-
-
0030859121
-
Hepatitis C virus core protein induces hepatic steatosis in transgenic mice
-
Moriya K, Yotsuyanagi H, Shintani Y, Fujie H, Ishibashi K, Matsuura Y, et al. Hepatitis C virus core protein induces hepatic steatosis in transgenic mice. J Gen Virol 1997;78(pt 7):1527-1531.
-
(1997)
J Gen Virol
, vol.78
, Issue.PART 7
, pp. 1527-1531
-
-
Moriya, K.1
Yotsuyanagi, H.2
Shintani, Y.3
Fujie, H.4
Ishibashi, K.5
Matsuura, Y.6
-
76
-
-
1542287381
-
Hepatitis C virus infection and diabetes: Direct involvement of the virus in the development of insulin resistance
-
Shintani Y, Fujie H, Miyoshi H, Tsutsumi T, Tsukamoto K, Kimura S, et al. Hepatitis C virus infection and diabetes: Direct involvement of the virus in the development of insulin resistance. Gastroenterology 2004;126:840-848.
-
(2004)
Gastroenterology
, vol.126
, pp. 840-848
-
-
Shintani, Y.1
Fujie, H.2
Miyoshi, H.3
Tsutsumi, T.4
Tsukamoto, K.5
Kimura, S.6
-
77
-
-
0043037223
-
High body mass index is an independent risk factor for nonresponse to antiviral treatment in chronic hepatitis C
-
Bressler BL, Guindi M, Tomlinson G, Heathcote J. High body mass index is an independent risk factor for nonresponse to antiviral treatment in chronic hepatitis C. Hepatology 2003;38:639-644.
-
(2003)
Hepatology
, vol.38
, pp. 639-644
-
-
Bressler, B.L.1
Guindi, M.2
Tomlinson, G.3
Heathcote, J.4
-
78
-
-
33745560465
-
Impact of obesity on treatment of chronic hepatitis C
-
Charlton MR, Pockros PJ, Harrison SA. Impact of obesity on treatment of chronic hepatitis C. Hepatology 2006;43:1177-1186.
-
(2006)
Hepatology
, vol.43
, pp. 1177-1186
-
-
Charlton, M.R.1
Pockros, P.J.2
Harrison, S.A.3
-
79
-
-
0038122773
-
Effect of treatment with peginterferon or interferon alfa-2b and ribavirin on steatosis in patients infected with hepatitis C
-
Poynard T, Ratziu V, McHutchison J, Manns M, Goodman Z, Zeuzem S, et al. Effect of treatment with peginterferon or interferon alfa-2b and ribavirin on steatosis in patients infected with hepatitis C. Hepatology 2003;38:75-85.
-
(2003)
Hepatology
, vol.38
, pp. 75-85
-
-
Poynard, T.1
Ratziu, V.2
McHutchison, J.3
Manns, M.4
Goodman, Z.5
Zeuzem, S.6
-
80
-
-
0141682739
-
Nonalcoholic fatty liver disease in patients with hepatitis C is associated with features of the metabolic syndrome
-
Sanyal AJ, Contos MJ, Sterling RK, Luketic VA, Shiffman ML, Stravitz RT, et al. Nonalcoholic fatty liver disease in patients with hepatitis C is associated with features of the metabolic syndrome. Am J Gastroenterol 2003;98:2064-2071.
-
(2003)
Am J Gastroenterol
, vol.98
, pp. 2064-2071
-
-
Sanyal, A.J.1
Contos, M.J.2
Sterling, R.K.3
Luketic, V.A.4
Shiffman, M.L.5
Stravitz, R.T.6
-
81
-
-
15744381704
-
Insulin resistance impairs sustained response rate to peginterferon plus ribavirin in chronic hepatitis C patients
-
Romero-Gomez M, Del Mar Viloria M, Andrade RJ, Salmeron J, Diago M, Fernandez-Rodriguez CM, et al. Insulin resistance impairs sustained response rate to peginterferon plus ribavirin in chronic hepatitis C patients. Gastroenterology 2005;128:636-641.
-
(2005)
Gastroenterology
, vol.128
, pp. 636-641
-
-
Romero-Gomez, M.1
Del Mar Viloria, M.2
Andrade, R.J.3
Salmeron, J.4
Diago, M.5
Fernandez-Rodriguez, C.M.6
-
82
-
-
20444472642
-
Effect of significant histologic steatosis or steatohepatitis on response to antiviral therapy in patients with chronic hepatitis C
-
Harrison SA, Brunt EM, Qazi RA, Oliver DA, Neuschwander-Tetri BA, Di Bisceglie AM, et al. Effect of significant histologic steatosis or steatohepatitis on response to antiviral therapy in patients with chronic hepatitis C. Clin Gastroenterol Hepatol 2005;3:604-609.
-
(2005)
Clin Gastroenterol Hepatol
, vol.3
, pp. 604-609
-
-
Harrison, S.A.1
Brunt, E.M.2
Qazi, R.A.3
Oliver, D.A.4
Neuschwander-Tetri, B.A.5
Di Bisceglie, A.M.6
-
83
-
-
14844315025
-
Liver steatosis is an independent risk factor for treatment failure in patients with chronic hepatitis C
-
Thomopoulos KC, Theocharis GJ, Tsamantas AC, Siagris D, Dimitropoulou D, Gogos CA, et al. Liver steatosis is an independent risk factor for treatment failure in patients with chronic hepatitis C. Eur J Gastroenterol Hepatol 2005;17:149-153.
-
(2005)
Eur J Gastroenterol Hepatol
, vol.17
, pp. 149-153
-
-
Thomopoulos, K.C.1
Theocharis, G.J.2
Tsamantas, A.C.3
Siagris, D.4
Dimitropoulou, D.5
Gogos, C.A.6
-
84
-
-
22744435914
-
Insulin resistance plays a significant role in liver fibrosis in chronic hepatitis C and in the response to antiviral therapy
-
D'souza R, Sabin CA, Foster GR. Insulin resistance plays a significant role in liver fibrosis in chronic hepatitis C and in the response to antiviral therapy. Am J Gastroenterol 2005;100:1509-1515.
-
(2005)
Am J Gastroenterol
, vol.100
, pp. 1509-1515
-
-
D'souza, R.1
Sabin, C.A.2
Foster, G.R.3
-
85
-
-
33645932317
-
Hepatic steatosis is a predictor of poor response to interferon alpha-2b and ribavirin combination therapy in Japanese patients with chronic hepatitis C
-
Yaginuma R, Ikejima K, Okumura K, Kon K, Suzuki S, Takei Y, et al. Hepatic steatosis is a predictor of poor response to interferon alpha-2b and ribavirin combination therapy in Japanese patients with chronic hepatitis C. Hepatol Res 2006;35:19-25.
-
(2006)
Hepatol Res
, vol.35
, pp. 19-25
-
-
Yaginuma, R.1
Ikejima, K.2
Okumura, K.3
Kon, K.4
Suzuki, S.5
Takei, Y.6
-
86
-
-
33645968108
-
Effects of fatty liver and related factors on the efficacy of combination antiviral therapy in patients with chronic hepatitis C
-
Jian Wu Y, Shu Chen L, Gui Qiang W. Effects of fatty liver and related factors on the efficacy of combination antiviral therapy in patients with chronic hepatitis C. Liver Int 2006;26:166-172.
-
(2006)
Liver Int
, vol.26
, pp. 166-172
-
-
Jian Wu, Y.1
Shu Chen, L.2
Gui Qiang, W.3
-
87
-
-
33749589381
-
Impact of liver steatosis on the antiviral response in the hepatitis C virus-associated chronic hepatitis
-
Soresi M, Tripi S, Franco V, Giannitrapani L, Alessandri A, Rappa F, et al. Impact of liver steatosis on the antiviral response in the hepatitis C virus-associated chronic hepatitis. Liver Int 2006;26:1119-1125.
-
(2006)
Liver Int
, vol.26
, pp. 1119-1125
-
-
Soresi, M.1
Tripi, S.2
Franco, V.3
Giannitrapani, L.4
Alessandri, A.5
Rappa, F.6
-
88
-
-
0030052322
-
Tumor necrosis factor alpha gene expression and the response to interferon in chronic hepatitis C
-
Larrea E, Garcia N, Qian C, Civeira MP, Prieto J. Tumor necrosis factor alpha gene expression and the response to interferon in chronic hepatitis C. Hepatology 1996;23:210-217.
-
(1996)
Hepatology
, vol.23
, pp. 210-217
-
-
Larrea, E.1
Garcia, N.2
Qian, C.3
Civeira, M.P.4
Prieto, J.5
-
89
-
-
33745580391
-
Oxidative stress inhibits IFN-alpha-induced antiviral gene expression by blocking the JAK-STAT pathway
-
Di Bona D, Cippitelli M, Fionda C, Camma C, Licata A, Santoni A, et al. Oxidative stress inhibits IFN-alpha-induced antiviral gene expression by blocking the JAK-STAT pathway. J Hepatol 2006;45:271-279.
-
(2006)
J Hepatol
, vol.45
, pp. 271-279
-
-
Di Bona, D.1
Cippitelli, M.2
Fionda, C.3
Camma, C.4
Licata, A.5
Santoni, A.6
-
90
-
-
13844294333
-
Etanercept as an adjuvant to interferon and ribavirin in treatment-naive patients with chronic hepatitis C virus infection: A phase 2 randomized, double-blind, placebo-controlled study
-
Zein NN. Etanercept as an adjuvant to interferon and ribavirin in treatment-naive patients with chronic hepatitis C virus infection: A phase 2 randomized, double-blind, placebo-controlled study. J Hepatol 2005;42:315-322.
-
(2005)
J Hepatol
, vol.42
, pp. 315-322
-
-
Zein, N.N.1
-
91
-
-
0032695030
-
Independent predictors of liver fibrosis in patients with nonalcoholic steatohepatitis
-
Angulo P, Keach JC, Batts KP, Lindor KD. Independent predictors of liver fibrosis in patients with nonalcoholic steatohepatitis. Hepatology 1999;30:1356-1362.
-
(1999)
Hepatology
, vol.30
, pp. 1356-1362
-
-
Angulo, P.1
Keach, J.C.2
Batts, K.P.3
Lindor, K.D.4
-
92
-
-
0034950652
-
Nonalcoholic fatty liver disease: Predictors of nonalcoholic steatohepatitis and liver fibrosis in the severely obese
-
Dixon JB, Bhathal PS, O'Brien PE. Nonalcoholic fatty liver disease: predictors of nonalcoholic steatohepatitis and liver fibrosis in the severely obese. Gastroenterology 2001;121:91-100.
-
(2001)
Gastroenterology
, vol.121
, pp. 91-100
-
-
Dixon, J.B.1
Bhathal, P.S.2
O'Brien, P.E.3
-
93
-
-
4344628555
-
The clinical features, diagnosis and natural history of nonalcoholic fatty liver disease
-
viii
-
McCullough AJ. The clinical features, diagnosis and natural history of nonalcoholic fatty liver disease. Clin Liver Dis 2004;8:521-33, viii.
-
(2004)
Clin Liver Dis
, vol.8
, pp. 521-533
-
-
McCullough, A.J.1
-
95
-
-
0842321807
-
Diabetes increases the risk of chronic liver disease and hepatocellular carcinoma
-
El-Serag HB, Tran T, Everhart JE. Diabetes increases the risk of chronic liver disease and hepatocellular carcinoma. Gastroenterology 2004;126:460-468.
-
(2004)
Gastroenterology
, vol.126
, pp. 460-468
-
-
El-Serag, H.B.1
Tran, T.2
Everhart, J.E.3
-
96
-
-
15544382574
-
Diabetes increases the risk of hepatocellular carcinoma in the United States: A population based case control study
-
Davila JA, Morgan RO, Shaib Y, McGlynn KA, El-Serag HB. Diabetes increases the risk of hepatocellular carcinoma in the United States: A population based case control study. Gut 2005;54:533-539.
-
(2005)
Gut
, vol.54
, pp. 533-539
-
-
Davila, J.A.1
Morgan, R.O.2
Shaib, Y.3
McGlynn, K.A.4
El-Serag, H.B.5
-
97
-
-
0037714524
-
Hepatic steatosis is a risk factor for hepatocellular carcinoma in patients with chronic hepatitis C virus infection
-
Ohata K, Hamasaki K, Toriyama K, Matsumoto K, Saeki A, Yanagi K, et al. Hepatic steatosis is a risk factor for hepatocellular carcinoma in patients with chronic hepatitis C virus infection. Cancer (Phila) 2003;97:3036-3043.
-
(2003)
Cancer (Phila)
, vol.97
, pp. 3036-3043
-
-
Ohata, K.1
Hamasaki, K.2
Toriyama, K.3
Matsumoto, K.4
Saeki, A.5
Yanagi, K.6
-
98
-
-
85047694402
-
Hepatocyte-specific Pten deficiency results in steatohepatitis and hepatocellular carcinomas
-
Horie Y, Suzuki A, Kataoka E, Sasaki T, Hamada K, Sasaki J, et al. Hepatocyte-specific Pten deficiency results in steatohepatitis and hepatocellular carcinomas. J Clin Invest 2004;113:1774-1783.
-
(2004)
J Clin Invest
, vol.113
, pp. 1774-1783
-
-
Horie, Y.1
Suzuki, A.2
Kataoka, E.3
Sasaki, T.4
Hamada, K.5
Sasaki, J.6
-
99
-
-
0030936323
-
PTEN, a putative protein tyrosine phosphatase gene mutated in human brain, breast, and prostate cancer
-
Li J, Yen C, Liaw D, Podsypanina K, Bose S, Wang SI, et al. PTEN, a putative protein tyrosine phosphatase gene mutated in human brain, breast, and prostate cancer. Science 1997;275:1943-1947.
-
(1997)
Science
, vol.275
, pp. 1943-1947
-
-
Li, J.1
Yen, C.2
Liaw, D.3
Podsypanina, K.4
Bose, S.5
Wang, S.I.6
-
100
-
-
0023191508
-
Insulin resistance in essential hypertension
-
Ferrannini E, Buzzigoli G, Bonadonna R, Giorico MA, Oleggini M, Graziadei L, et al. Insulin resistance in essential hypertension. N Engl J Med 1987;317:350-357.
-
(1987)
N Engl J Med
, vol.317
, pp. 350-357
-
-
Ferrannini, E.1
Buzzigoli, G.2
Bonadonna, R.3
Giorico, M.A.4
Oleggini, M.5
Graziadei, L.6
-
101
-
-
0033552883
-
Atherosclerosis: An inflammatory disease
-
Ross R. Atherosclerosis: An inflammatory disease. N Engl J Med 1999;340:115-126.
-
(1999)
N Engl J Med
, vol.340
, pp. 115-126
-
-
Ross, R.1
-
102
-
-
34248572575
-
Metabolic syndrome: Recent prevalence in East and Southeast Asian populations
-
Nestel P, Lyu R, Low LP, Sheu WH, Nitiyanant W, Saito I, et al. Metabolic syndrome: Recent prevalence in East and Southeast Asian populations. Asia Pac J Clin Nutr 2007;16:362-367.
-
(2007)
Asia Pac J Clin Nutr
, vol.16
, pp. 362-367
-
-
Nestel, P.1
Lyu, R.2
Low, L.P.3
Sheu, W.H.4
Nitiyanant, W.5
Saito, I.6
-
103
-
-
0033613545
-
Novel modulator for endothelial adhesion molecules: Adipocyte-derived plasma protein adiponectin
-
Ouchi N, Kihara S, Arita Y, Maeda K, Kuriyama H, Okamoto Y, et al. Novel modulator for endothelial adhesion molecules: Adipocyte-derived plasma protein adiponectin. Circulation 1999;100:2473-2476.
-
(1999)
Circulation
, vol.100
, pp. 2473-2476
-
-
Ouchi, N.1
Kihara, S.2
Arita, Y.3
Maeda, K.4
Kuriyama, H.5
Okamoto, Y.6
-
104
-
-
0036139677
-
Adiponectin, metabolic risk factors, and car diovascular events among patients with end-stage renal disease
-
Zoccali C, Mallamaci F, Tripepi G, Benedetto FA, Cutrupi S, Parlongo S, et al. Adiponectin, metabolic risk factors, and car diovascular events among patients with end-stage renal disease. J Am Soc Nephrol 2002;13:134-141.
-
(2002)
J Am Soc Nephrol
, vol.13
, pp. 134-141
-
-
Zoccali, C.1
Mallamaci, F.2
Tripepi, G.3
Benedetto, F.A.4
Cutrupi, S.5
Parlongo, S.6
-
105
-
-
0037180472
-
Adiponectin reduces atherosclerosis in apolipoprotein E-deficient mice
-
Okamoto Y, Kihara S, Ouchi N, Nishida M, Arita Y, Kumada M, et al. Adiponectin reduces atherosclerosis in apolipoprotein E-deficient mice. Circulation 2002;106:2767-2770.
-
(2002)
Circulation
, vol.106
, pp. 2767-2770
-
-
Okamoto, Y.1
Kihara, S.2
Ouchi, N.3
Nishida, M.4
Arita, Y.5
Kumada, M.6
-
106
-
-
26244453309
-
Secondary prevention of macrovascular events in patients with type 2 diabetes in the PROactive Study (PROspective pioglitAzone Clinical Trial In macroVascular Events): A randomised controlled trial
-
Dormandy JA, Charbonnel B, Eckland DJ, Erdmann E, Massi-Benedetti M, Moules IK, et al. Secondary prevention of macrovascular events in patients with type 2 diabetes in the PROactive Study (PROspective pioglitAzone Clinical Trial In macroVascular Events): A randomised controlled trial. Lancet 2005;366:1279-1289.
-
(2005)
Lancet
, vol.366
, pp. 1279-1289
-
-
Dormandy, J.A.1
Charbonnel, B.2
Eckland, D.J.3
Erdmann, E.4
Massi-Benedetti, M.5
Moules, I.K.6
-
107
-
-
3042628302
-
Fatty liver, hypertension, and the metabolic syndrome
-
Diehl AM. Fatty liver, hypertension, and the metabolic syndrome. Gut 2004;53:923-924.
-
(2004)
Gut
, vol.53
, pp. 923-924
-
-
Diehl, A.M.1
-
108
-
-
33645963121
-
Similarities and differences in outcomes of cirrhosis due to nonalcoholic steatohepatitis and hepatitis C
-
Sanyal AJ, Banas C, Sargeant C, Luketic VA, Sterling RK, Stravitz RT, et al. Similarities and differences in outcomes of cirrhosis due to nonalcoholic steatohepatitis and hepatitis C. Hepatology 2006;43:682-689.
-
(2006)
Hepatology
, vol.43
, pp. 682-689
-
-
Sanyal, A.J.1
Banas, C.2
Sargeant, C.3
Luketic, V.A.4
Sterling, R.K.5
Stravitz, R.T.6
-
109
-
-
3042521502
-
Increased prevalence of fatty liver in arterial hypertensive patients with normal liver enzymes: Role of insulin resistance
-
Donati G, Stagni B, Piscaglia F, Venturoli N, Morselli-Labate AM, Rasciti L, et al. Increased prevalence of fatty liver in arterial hypertensive patients with normal liver enzymes: Role of insulin resistance. Gut 2004;53:1020-1023.
-
(2004)
Gut
, vol.53
, pp. 1020-1023
-
-
Donati, G.1
Stagni, B.2
Piscaglia, F.3
Venturoli, N.4
Morselli-Labate, A.M.5
Rasciti, L.6
-
110
-
-
33751545838
-
A placebo-controlled trial of pioglitazone in subjects with nonalcoholic steatohepatitis
-
Belfort R, Harrison SA, Brown K, Darland C, Finch J, Hardies J, et al. A placebo-controlled trial of pioglitazone in subjects with nonalcoholic steatohepatitis. N Engl J Med 2006;355:2297-2307.
-
(2006)
N Engl J Med
, vol.355
, pp. 2297-2307
-
-
Belfort, R.1
Harrison, S.A.2
Brown, K.3
Darland, C.4
Finch, J.5
Hardies, J.6
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