Aberrant hepatic expression of PPARγ2 stimulates hepatic lipogenesis in a mouse model of obesity, insulin resistance, dyslipidemia, and hepatic steatosis

Journal of Biological Chemistry

Volumn 281, Issue 49, 2006, Pages 37603-37615

  Zhang, Yuan Li ^a   Hernandez Ono, Antonio ^a   Siri, Patty ^a   Weisberg, Stuart ^a   Conlon, Donna ^a   Graham, Mark J ^b   Crooke, Rosanne M ^b   Huang, Li Shin ^a   Ginsberg, Henry N ^a,c  

^a Columbia University ^*  (United States)

^b ISIS PHARMACEUTICALS   (United States)

^c Och Spine at New York Presbyterian Hospitals   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ENZYME KINETICS; FATTY ACIDS; MOLECULAR BIOLOGY; PROTEINS; RNA;

HEPATIC LIPOGENESIS; HEPATIC STEATOSIS; OLIGONUCLEOTIDE; RECEPTOR;

INSULIN;

ACETYL COENZYME A CARBOXYLASE; ACYL COENZYME A DESATURASE; APOLIPOPROTEIN B; CD36 ANTIGEN; FATTY ACID SYNTHASE; MESSENGER RNA; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA 2; STEROL REGULATORY ELEMENT BINDING PROTEIN 1C;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL STIMULATION; CONTROLLED STUDY; DYSLIPIDEMIA; ENZYME ACTIVITY; FATTY LIVER; FEMALE; GENE EXPRESSION; GENETIC ANALYSIS; INSULIN RESISTANCE; LIPOGENESIS; LIVER; MALE; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; OBESITY; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN EXPRESSION; PROTEIN METABOLISM; REDUCTION;

ADIPOSE TISSUE, BROWN; ANIMALS; APOLIPOPROTEINS B; BASE SEQUENCE; DISEASE MODELS, ANIMAL; DNA PRIMERS; DYSLIPIDEMIAS; FATTY LIVER; FEMALE; GENE EXPRESSION; HUMANS; INSULIN RESISTANCE; LIPOGENESIS; LIVER; MALE; MICE; MICE, CONGENIC; MICE, INBRED C57BL; MICE, TRANSGENIC; OBESITY; PPAR GAMMA; RNA, MESSENGER;

EID: 33845984572     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M604709200     Document Type: Article

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