Pathophysiological importance of aggregated damaged proteins

Free Radical Biology and Medicine

Volumn 71, Issue , 2014, Pages 70-89

  Höhn, Annika ^a   Jung, Tobias ^a   Grune, Tilman ^a  

^a FRIEDRICH SCHILLER UNIVERSITY JENA   (Germany)

Author keywords

Autophagy; Free radicals; Lipofuscin; Proteasome; Protein aggregates; Protein oxidation

Indexed keywords

ARGININE; ARSENIC TRIOXIDE; BECLIN 1; C REACTIVE PROTEIN; CARRIER PROTEIN; CATHEPSIN; CATHEPSIN D; CELL ADHESION MOLECULE; CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN; CYSTEINE; DNA BASE; GROWTH FACTOR; HISTIDINE; HUNTINGTIN; INTERLEUKIN 6; LEUCINE; LIPOFUSCIN; METHIONINE; MITOGEN ACTIVATED PROTEIN KINASE P38; PEPTIDE TRANSPORTER 1; PHENYLALANINE; POLYDEOXYRIBONUCLEOTIDE SYNTHASE; POLYUBIQUITIN; PROTEASOME; REACTIVE OXYGEN METABOLITE; RIBONUCLEASE A; TRYPTOPHAN; TYROSINE; UBIQUITIN; UBIQUITINATED PROTEIN; PROTEIN; PROTEIN AGGREGATE;

ADAPTIVE IMMUNITY; ALZHEIMER DISEASE; ANTIBODY PRODUCTION; ARTHRITIS; ATHEROSCLEROSIS; AUTOIMMUNITY; AUTOOXIDATION; AUTOPHAGOSOME; AUTOPHAGY; CAENORHABDITIS ELEGANS; CELL FUNCTION; CELL METABOLISM; CELL SURFACE; CELL VIABILITY; CEREBROVASCULAR ACCIDENT; DEGENERATIVE DISEASE; DIABETES MELLITUS; ENDOCYTOSIS; ENDOPLASMIC RETICULUM STRESS; ENVIRONMENTAL STRESS; EXTRACELLULAR MATRIX; GENE EXPRESSION; GENOTYPE ENVIRONMENT INTERACTION; GLYCATION; HUMAN; HUNTINGTON CHOREA; LIPID PEROXIDATION; LYSOSOME; MACROAUTOPHAGY; METABOLIC SYNDROME X; MICROAUTOPHAGY; MOLECULAR INTERACTION; MOLECULAR WEIGHT; NONHUMAN; NUCLEOPHILICITY; OXIDATION; OXIDATIVE STRESS; PARKINSON DISEASE; PATHOPHYSIOLOGY; PRIORITY JOURNAL; PROTEIN AGGREGATION; PROTEIN CROSS LINKING; PROTEIN DEGRADATION; PROTEIN EXPRESSION; PROTEIN HOMEOSTASIS; PROTEIN MODIFICATION; PROTEIN PROTEIN INTERACTION; PROTEIN STRUCTURE; REVIEW; SIGNAL TRANSDUCTION; AGING; ANIMAL; CHEMISTRY; HOMEOSTASIS; METABOLISM; OXIDATION REDUCTION REACTION; PATHOLOGY; PROTEIN PROCESSING; PROTEINOSIS;

AGING; ANIMALS; AUTOPHAGY; HOMEOSTASIS; HUMANS; LYSOSOMES; OXIDATION-REDUCTION; OXIDATIVE STRESS; PROTEASOME ENDOPEPTIDASE COMPLEX; PROTEIN AGGREGATES; PROTEIN AGGREGATION, PATHOLOGICAL; PROTEIN PROCESSING, POST-TRANSLATIONAL; PROTEINS; PROTEOLYSIS; REACTIVE OXYGEN SPECIES;

EID: 84898041863     PISSN: 08915849     EISSN: 18734596     Source Type: Journal    
DOI: 10.1016/j.freeradbiomed.2014.02.028     Document Type: Review

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