Acyl-CoA-induced generation of reactive oxygen species in mitochondrial preparations is due to the presence of peroxisomes

Free Radical Biology and Medicine

Volumn 47, Issue 5, 2009, Pages 503-509

  Schönfeld, Peter ^a   Dymkowska, Dorota ^b   Wojtczak, Lech ^b  

^a OTTO VON GUERICKE UNIVERSITY   (Germany)

^b NENCKI INSTITUTE OF EXPERIMENTAL BIOLOGY   (Poland)

Author keywords

Acyl CoA; Free radicals; Mitochondria; Palmitoyl CoA; Peroxisomes; Reactive oxygen species

Indexed keywords

ACYL COENZYME A; ANTIMYCIN A1; PALMITOYL COENZYME A; REACTIVE OXYGEN METABOLITE; ROTENONE; URATE OXIDASE;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; BRAIN MITOCHONDRION; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME SUBSTRATE; FEMALE; HEART MITOCHONDRION; LIVER MITOCHONDRION; MITOCHONDRIAL RESPIRATION; MOLECULAR PROBE; NONHUMAN; OXIDATION REDUCTION REACTION; PEROXISOME; PRIORITY JOURNAL; RAT;

ACYL COENZYME A; ANIMALS; BRAIN; CELL FRACTIONATION; CELL RESPIRATION; DOSE-RESPONSE RELATIONSHIP, DRUG; FEMALE; MITOCHONDRIA, HEART; MITOCHONDRIA, LIVER; PALMITOYL COENZYME A; PEROXISOMES; RATS; RATS, WISTAR; REACTIVE OXYGEN SPECIES; TISSUE EXTRACTS; URATE OXIDASE;

RATTUS;

EID: 67650710732     PISSN: 08915849     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.freeradbiomed.2009.05.006     Document Type: Article

References (36)

1. Wojtczak L., and Schönfeld P. Effect of fatty acids on energy coupling processes in mitochondria. Biochim. Biophys. Acta 1183 (1993) 41-57
2. Furono T., Kanno T., Arita K., Asami M., Utsumi T., Doi Y., Inoue M., and Utsumi K. Roles of long chain fatty acids and carnitine in mitochondrial membrane permeability transition. Biochem. Pharmacol. 62 (2001) 1037-1046
3. Korge P., Honda H.M., and Weiss J.N. Effects of fatty acids in isolated mitochondria: implications for ischemic injury and cardioprotection. Am. J. Physiol. Heart Circ. Physiol. 285 (2003) H259-H269
4. Tominaga H., Katoh H., Odagiri K., Takeuchi Y., Kawashima H., Saotome M., Urushida T., Satoh H., and Hayashi H. Different effects of palmitoyl-l-carnitine and palmitoyl-CoA on mitochondrial function in rat ventricular myocytes. Am. J. Physiol. Heart Circ. Physiol. 295 (2008) H105-H112
5. Schönfeld P., and Wojtczak L. Fatty acids as modulators of the cellular production of reactive oxygen species. Free Radic. Biol. Med. 45 (2008) 231-241
6. Silveira L.R., Fiamoncini J., Hirabara S.M., Procopio J., Cambiagli T.D., Pinheiro C.H.J., Lopes L.R., and Curi R. Updating the effects of fatty acids on skeletal muscle. J. Cell. Physiol. 217 (2008) 1-12
7. Cocco T., Di Paola M., Papa S., and Lorusso M. Arachidonic acid interaction with the mitochondrial electron transport chain promotes reactive oxygen species generation. Free Radic. Biol. Med. 27 (1999) 51-59
8. Di Paola M., and Lorusso M. Interaction of free fatty acids with mitochondria: coupling, uncoupling and permeability transition. Biochim. Biophys. Acta 1757 (2006) 1330-1337
9. Inoguchi T., Li P., Umeda F., Yu H.Y., Kakimoto M., Imamura M., Aoki T., Etoh T., Hashimoto T., Naruse M., Sano H., Utsumi H., and Nawata H. High glucose level and free fatty acid stimulate reactive oxygen species production through protein kinase C-dependent activation of NAD(P)H oxidase in cultured vascular cells. Diabetes 49 (2000) 1939-1945
10. 18 fatty acids in Jurkat and Raji cells. Clin. Sci. 108 (2005) 245-253
11. Ciapaite J., Bakker S.J.L., Diamant M., van Eikenhorst G., Heine R.J., Westerhoff H.V., and Krab K. Metabolic control of mitochondrial properties by adenine nucleotide translocator determines palmitoyl-CoA effects: implications for a mechanism linking obesity and type 2 diabetes. FEBS J. 273 (2006) 5288-5302
12. Pande S.V., and Blanchaer M.C. Reversible inhibition of mitochondrial adenosine diphosphate phosphorylation by long chain acyl coenzyme A esters. J. Biol. Chem. 246 (1971) 402-411
13. 2 release at mitochondrial complex I. J. Bioenerg. Biomembr. 40 (2008) 9-18
14. Halperin M.L., Robinson B.H., and Fritz J.B. Effects of palmitoyl CoA on citrate and malate transport by rat liver mitochondria. Proc. Natl. Acad. Sci. USA 69 (1972) 1003-1007
15. Morel F., Lauquin G., Lunardi J., Duszynski J., and Vignais P.V. An appraisal of the functional significance of the inhibitory effect of long chain acyl-CoAs on mitochondrial transports. FEBS Lett. 39 (1974) 133-138
16. Steinbrecht I., and Kunz W. Use of "cycling" technique for random quantitative determination of the degree of reduction of NAD and NADP system in rat liver mitochondria with continuous recording of the measurements. Acta Biol. Med. Ger. 25 (1970) 731-747
17. Graham J.M. Isolation of peroxisomes from tissues and cells by differential and density gradient centrifugation. Curr. Protoc. Cell Biol. (2001) Chap. 3, Unit 3.5
18. 2+-ions on the properties of rat heart mitochondria in dependence on the preparation. Acta Biol. Med. Ger. 37 (1978) 31-38
19. Liu Y., Fiskum G., and Schubert D. Generation of reactive oxygen species by the mitochondrial electron transport chain. J. Neurochem. 80 (2002) 780-787
20. Johnson-Cadwell L.J., Jekabsons M.B., Wang A., and Polster B.M. Nicholls, D.G. 'Mild uncoupling' does not decrease mitochondrial superoxide levels in cultured cerebellar granule neurons but decreases spare respiratory capacity and increases toxicity to glutamate and oxidative stress. J. Neurochem. 101 (2007) 1619-1631
21. Gardner P.R. Aconitase: sensitive target and measure of superoxide. Methods Enzymol. 349 (2002) 9-23
22. 2 release from intact peroxisomes. Biochem. J. 363 (2002) 483-491
23. Schönfeld P., and Reiser R. Rotenone-like action of the branched-chain phytanic acid induces oxidative stress in mitochondria. J. Biol. Chem. 281 (2006) 7136-7142
24. Schönfeld P., and Wojtczak L. Fatty acids decrease mitochondrial generation of reactive oxygen species at the reverse electron transport but increase it at the forward transport. Biochim. Biophys. Acta 1767 (2007) 1032-1040
25. Lambertucci R.H., Hirabara S.M., Siveira L.R., Levada-Pires A.C., Curi R., and Phiton-Curi T.C. Palmitate increases superoxide production through mitochondrial electron transport chain and NADPH oxidase activity in skeletal muscle cells. J. Cell. Physiol. 216 (2008) 796-804
26. Bulteau A.L., Ikeda-Saito M., and Szweda L.I. Redox-dependent modulation of aconitase activity in intact mitochondria. Biochemistry 42 (2003) 14846-14855
27. Lazarow P.B., and de Duve C. A fatty acyl-CoA oxidizing system in rat liver peroxisomes: enhancement by clofibrate, a hypolipidemic drug. Proc. Natl. Acad. Sci. USA 73 (1976) 2043-2046
28. Lazarow P.B. Rat liver peroxisomes catalyze the β oxidation of fatty acids. J. Biol. Chem. 253 (1978) 1522-1528
29. Inestrosa N.C., Bronfman M., and Leighton F. Properties of fatty acyl-CoA oxidase from rat liver: a peroxisomal flavoprotein. Life Sci. 25 (1979) 1127-1135
30. Osumi T., and Hashimoto T. Acyl-CoA oxidase of rat liver: a new enzyme for fatty acid oxidation. Biochem. Biophys. Res. Commun. 83 (1978) 479-485
31. Radi R., Turrens J.F., Chang L.Y., Bush K.M., Crapo J.D., and Freeman B.A. Detection of catalase in rat heart mitochondria. J. Biol. Chem. 266 (1991) 22028-22034
32. Schrader M., and Yoon Y. Mitochondria and peroxisomes: are the 'big brother' and the 'little sister' closer than assumed?. BioEssays 29 (2007) 1105-1114
33. Schrader M., and Fahimi H.D. Peroxisomes and oxidative stress. Biochim. Biophys. Acta 1763 (2006) 1755-1766
34. Faergeman N.J., and Knudsen J. Role of long-chain fatty acyl-CoA esters in the regulation of metabolism and in cell signalling. Biochem. J. 323 (1997) 1-12
35. Schrader M., and Fahimi H.D. Mammalian peroxisomes and reactive oxygen species. Histochem. Cell Biol. 122 (2004) 383-393
36. Lesnefsky E.J., Moghaddas S., Tandler B., Kerner J., and Hoppel C.L. Mitochondrial dysfunction in cardiac disease: ischemia-reperfusion, aging, and heart failure. J. Mol. Cell. Cardiol. 33 (2001) 1065-1089