The role of the proteasome in the generation of MHC class I ligands and immune responses

Cellular and Molecular Life Sciences

Volumn 68, Issue 9, 2011, Pages 1491-1502

  Sijts, E J A M ^a   Kloetzel, P M ^b  

^a UTRECHT UNIVERSITY   (Netherlands)

^b CHARITÉ UNIVERSITÄTSMEDIZIN BERLIN   (Germany)

Author keywords

Antigen processing; Immune responses; Immunosubunits; MHC class I; PA28; Peptide splicing; Proteasome; TCR repertoire

Indexed keywords

CYTOKINE; ENZYME ACTIVATOR; GAMMA INTERFERON; IMMUNOPROTEASOME; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 1; PROTEASOME; PROTEASOME ACTIVATOR 28; PROTEINASE; T LYMPHOCYTE RECEPTOR; UNCLASSIFIED DRUG;

ANTIGEN PRESENTATION; CD8+ T LYMPHOCYTE; CELL LINEAGE; CELL SELECTION; CELL STIMULATION; CELL TYPE; CYTOKINE PRODUCTION; ENZYME ACTIVITY; ENZYME SUBUNIT; EPITHELIUM CELL; HUMAN; IMMUNE RESPONSE; IMMUNOREGULATION; INFECTION; INFLAMMATION; LIGAND BINDING; MAMMAL CELL; NONHUMAN; PROTEIN DEGRADATION; PROTEIN EXPRESSION; REVIEW; THYMUS; UBIQUITIN PROTEASOME SYSTEM;

ANIMALS; ANTIGEN PRESENTATION; CD8-POSITIVE T-LYMPHOCYTES; CYTOKINES; HISTOCOMPATIBILITY ANTIGENS CLASS I; HUMANS; LIGANDS; LYMPHOCYTE ACTIVATION; MICE; MUSCLE PROTEINS; PEPTIDES; PROTEASOME ENDOPEPTIDASE COMPLEX; RECEPTORS, ANTIGEN, T-CELL; THYMUS GLAND; UBIQUITINS;

MAMMALIA;

EID: 79958772781     PISSN: 1420682X     EISSN: 14209071     Source Type: Journal    
DOI: 10.1007/s00018-011-0657-y     Document Type: Review

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