The mitochondrial-lysosomal axis theory of aging: Accumulation of damaged mitochondria as a result of imperfect autophagocytosis

European Journal of Biochemistry

Volumn 269, Issue 8, 2002, Pages 1996-2002

  Brunk, Ulf T ^a,b   Terman, Alexei ^a  

^a LINKÖPING UNIVERSITY   (Sweden)

^b LINKÖPING UNIVERSITY HOSPITAL   (Sweden)

Author keywords

Aging; Autophagocytosis; Lipofuscin; Lysosomes; Mitochondria; Oxidative stress

Indexed keywords

ADENOSINE TRIPHOSPHATE; ALDEHYDE; CYTOCHROME; FERRITIN; HYDROXYL RADICAL; LIPOFUSCIN; LYSOSOME ENZYME; METALLOPROTEIN; REACTIVE OXYGEN METABOLITE;

AGING; APOPTOSIS; AUTOPHAGY; CELL FUNCTION; CELL ORGANELLE; CELL ULTRASTRUCTURE; DISORDERS OF MITOCHONDRIAL FUNCTIONS; DNA REPLICATION; ENERGY YIELD; LYSOSOME; MITOCHONDRIAL RESPIRATION; MITOCHONDRION; MITOSIS; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN DEGRADATION; SHORT SURVEY; THEORY;

AGING; ANIMALS; AUTOPHAGY; LIPOFUSCIN; LYSOSOMES; MITOCHONDRIA; OXIDATIVE STRESS; REACTIVE OXYGEN SPECIES;

EID: 0036236006     PISSN: 00142956     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1432-1033.2002.02869.x     Document Type: Short Survey

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