Human stem cell models of neurodegeneration: A novel approach to study mechanisms of disease development

Acta Neuropathologica

Volumn 127, Issue 2, 2014, Pages 151-173

  Hargus, Gunnar ^a   Ehrlich, Marc ^a   Hallmann, Anna Lena ^a   Kuhlmann, Tanja ^a  

^a UNIVERSITY HOSPITAL MÜNSTER   (Germany)

Author keywords

ES cells; iN cells; iPS cells; Neurodegeneration; Neurodegenerative diseases

Indexed keywords

BIOCHEMICAL MARKER; KRUPPEL LIKE FACTOR 4; MEMBRANE PROTEIN; MICROTUBULE ASSOCIATED PROTEIN; PARKIN; PRESENILIN 1; PRESENILIN 2; PROGRANULIN; REACTIVE OXYGEN METABOLITE; TRANSCRIPTION FACTOR SOX2;

ALZHEIMER DISEASE; AMYOTROPHIC LATERAL SCLEROSIS; DEGENERATIVE DISEASE; DISEASE COURSE; DYSAUTONOMIA; EMBRYONIC STEM CELL; FRIEDREICH ATAXIA; FRONTOTEMPORAL DEMENTIA; GAUCHER DISEASE; GENETIC RISK; HEREDITARY MOTOR SENSORY NEUROPATHY; HUMAN; HUNTINGTON CHOREA; IN VITRO STUDY; NERVE CELL DIFFERENTIATION; NERVE DEGENERATION; NONHUMAN; ONCOGENE C MYC; OXIDATIVE STRESS; PARKINSON DISEASE; PINK1 MUTANT (DROSOPHILA); PLURIPOTENT STEM CELL; PRIORITY JOURNAL; REVIEW; RISK FACTOR; SPINAL MUSCULAR ATROPHY; SPINOCEREBELLAR DEGENERATION; STORAGE DISEASE;

CELLS, CULTURED; DISEASE PROGRESSION; HUMANS; INDUCED PLURIPOTENT STEM CELLS; MODELS, BIOLOGICAL; MUTATION; NEURODEGENERATIVE DISEASES; NEURONS;

EID: 84896730248     PISSN: 00016322     EISSN: 14320533     Source Type: Journal    
DOI: 10.1007/s00401-013-1222-6     Document Type: Review

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