-
1
-
-
13844271605
-
Specification of motoneurons from human embryonic stem cells
-
Li, X. J. et al. Specification of motoneurons from human embryonic stem cells. Nature Biotechnol. 23, 215-221 (2005).
-
(2005)
Nature Biotechnol
, vol.23
, pp. 215-221
-
-
Li, X.J.1
-
2
-
-
4344592974
-
Derivation of midbrain dopamine neurons from human embryonic stem cells
-
DOI 10.1073/pnas.0404700101
-
Perrier, A. L. et al. From the cover: derivation of midbrain dopamine neurons from human embryonic stem cells. Proc. Natl Acad. Sci. USA 101, 12543-12548 (2004). (Pubitemid 39122060)
-
(2004)
Proceedings of the National Academy of Sciences of the United States of America
, vol.101
, Issue.34
, pp. 12543-12548
-
-
Perrier, A.L.1
Tabar, V.2
Barberi, T.3
Rubio, M.E.4
Bruses, J.5
Topf, N.6
Harrison, N.L.7
Studer, L.8
-
3
-
-
41849093685
-
Therapeutic cloning in individual parkinsonian mice
-
DOI 10.1038/nm1732, PII NM1732
-
Tabar, V. et al. Therapeutic cloning in individual parkinsonian mice. Nature Med. 14, 379-381 (2008). (Pubitemid 351499386)
-
(2008)
Nature Medicine
, vol.14
, Issue.4
, pp. 379-381
-
-
Tabar, V.1
Tomishima, M.2
Panagiotakos, G.3
Wakayama, S.4
Menon, J.5
Chan, B.6
Mizutani, E.7
Al-Shamy, G.8
Ohta, H.9
Wakayama, T.10
Studer, L.11
-
4
-
-
42649130264
-
Neurons derived from reprogrammed fibroblasts functionally integrate into the fetal brain and improve symptoms of rats with Parkinson's disease
-
DOI 10.1073/pnas.0801677105
-
Wernig, M. et al. Neurons derived from reprogrammed fibroblasts functionally integrate into the fetal brain and improve symptoms of rats with Parkinson's disease. Proc. Natl Acad. Sci. USA 105, 5856-5861 (2008). (Pubitemid 351758462)
-
(2008)
Proceedings of the National Academy of Sciences of the United States of America
, vol.105
, Issue.15
, pp. 5856-5861
-
-
Wernig, M.1
Zhao, J.-P.2
Pruszak, J.3
Hedlund, E.4
Fu, D.5
Soldner, F.6
Broccoli, V.7
Constantine-Paton, M.8
Isacson, O.9
Jaenisch, R.10
-
5
-
-
74949087489
-
Stem cellsinhuman neurodegenerative disorders-time for clinical translation?
-
Lindvall, O. &Kokaia, Z. Stem cellsinhuman neurodegenerative disorders-time for clinical translation? J. Clin. Invest. 120, 29-40 (2010).
-
(2010)
J. Clin. Invest.
, vol.120
, pp. 29-40
-
-
Lindvall, O.1
Kokaia, Z.2
-
6
-
-
38349062515
-
Human ES cell-derived neural rosettes reveal a functionally distinct early neural stem cell stage
-
Elkabetz, Y. et al. Human ES cell-derived neural rosettes reveal a functionally distinct early neural stem cell stage. Genes Dev. 22, 152-165 (2008).
-
(2008)
Genes Dev
, vol.22
, pp. 152-165
-
-
Elkabetz, Y.1
-
7
-
-
33750706917
-
Functional engraftment of human ES cell-derived dopaminergic neurons enriched by coculture with telomerase-immortalized midbrain astrocytes
-
DOI 10.1038/nm1495, PII NM1495
-
Roy, N. S. et al. Functional engraftment of human ES cell-derived dopaminergic neurons enriched by coculture with telomerase-immortalized midbrain astrocytes. Nature Med. 12, 1259-1268 (2006). (Pubitemid 44706928)
-
(2006)
Nature Medicine
, vol.12
, Issue.11
, pp. 1259-1268
-
-
Roy, N.S.1
Cleren, C.2
Singh, S.K.3
Yang, L.4
Beal, M.F.5
Goldman, S.A.6
-
8
-
-
38549159511
-
The foxa2genecontrols the birth and spontaneous degeneration of dopamine neurons in old age
-
Kittappa, R., Chang, W. W., Awatramani, R. B. &McKay, R. D. The foxa2genecontrols the birth and spontaneous degeneration of dopamine neurons in old age. PLoS Biol. 5, e325 (2007).
-
(2007)
PLoS Biol
, vol.5
-
-
Kittappa, R.1
Chang, W.W.2
Awatramani, R.B.3
McKay, R.D.4
-
9
-
-
34548186224
-
Foxa1 and Foxa2 regulate multiple phases of midbrain dopaminergic neuron development in a dosage-dependent manner
-
DOI 10.1242/dev.000141
-
Ferri, A. L. et al. Foxa1 and Foxa2 regulate multiple phases of midbrain dopaminergic neurondevelopmentinadosage-dependent manner. Development 134, 2761-2769 (2007). (Pubitemid 47307232)
-
(2007)
Development
, vol.134
, Issue.15
, pp. 2761-2769
-
-
Ferri, A.L.M.1
Lin, W.2
Mavromatakis, Y.E.3
Wang, J.C.4
Sasaki, H.5
Whitsett, J.A.6
Ang, S.-L.7
-
10
-
-
23444440157
-
Floor plate and motor neuron induction by vhh-1, a vertebrate homolog of hedgehog expressed by the notochord
-
DOI 10.1016/0092-8674(94)90514-2
-
Roelink, H. et al. Floor plate and motor neuron induction by vhh-1, a vertebrate homolog of hedgehog expressed by the notochord. Cell 76, 761-775 (1994). (Pubitemid 24070659)
-
(1994)
Cell
, vol.76
, Issue.4
, pp. 761-775
-
-
Roelink, H.1
Augsburger, A.2
Heemskerk, J.3
Korzh, V.4
Norlin, S.5
Ruiz I Altaba, A.6
Tanabe, Y.7
Placzek, M.8
Edlund, T.9
Jessell, T.M.10
Dodd, J.11
-
11
-
-
0029162584
-
Dorsal differentiation of neural plate cells induced by bmp-mediated signals from epidermal ectoderm
-
Liem, K. F., Tremml, G., Roelink, H. & Jessell, T. M. Dorsal differentiation of neural plate cells induced by BMP-mediated signals from epidermal ectoderm. Cell 82, 969-979 (1995).
-
(1995)
Cell
, vol.82
, pp. 969-979
-
-
Liem, K.F.1
Tremml, G.2
Roelink, H.3
Jessell, T.M.4
-
12
-
-
77949892562
-
Efficient derivation of functional floor plate tissue from human embryonic stem cells
-
Fasano, C. A., Chambers, S. M., Lee, G., Tomishima, M. J. & Studer, L. Efficient derivation of functional floor plate tissue from human embryonic stem cells. Cell Stem Cell 6, 336-347 (2010).
-
(2010)
Cell Stem Cell
, vol.6
, pp. 336-347
-
-
Fasano, C.A.1
Chambers, S.M.2
Lee, G.3
Tomishima, M.J.4
Studer, L.5
-
13
-
-
62149125434
-
Highly efficient neural conversionofhumanesand ipscells by dual inhibition of SMAD signaling
-
Chambers, S. M. et al. Highly efficient neural conversionofhumanESand iPScells by dual inhibition of SMAD signaling. Nature Biotechnol. 27, 275-280 (2009).
-
(2009)
Nature Biotechnol
, vol.27
, pp. 275-280
-
-
Chambers, S.M.1
-
14
-
-
0036499974
-
Wnt signaling plays an essential role in neuronal specification of the dorsal spinal cord
-
DOI 10.1101/gad.937102
-
Muroyama, Y., Fujihara, M., Ikeya, M., Kondoh, H. & Takada, S. Wnt signaling plays an essential role in neuronal specification of the dorsal spinal cord. Genes Dev. 16, 548-553 (2002). (Pubitemid 34212487)
-
(2002)
Genes and Development
, vol.16
, Issue.5
, pp. 548-553
-
-
Muroyama, Y.1
Fujihara, M.2
Ikeya, M.3
Kondoh, H.4
Takada, S.5
-
15
-
-
58849098556
-
Wnt antagonism of shh facilitates midbrain floor plate neurogenesis
-
Joksimovic, M. et al. Wnt antagonism of Shh facilitates midbrain floor plate neurogenesis. Nature Neurosci. 12, 125-131 (2009).
-
(2009)
Nature Neurosci
, vol.12
, pp. 125-131
-
-
Joksimovic, M.1
-
16
-
-
79959999016
-
Differential requirement for the dual functions of beta-catenin in embryonic stem cell self-renewal and germ layer formation
-
Lyashenko, N. et al. Differential requirement for the dual functions of beta-catenin in embryonic stem cell self-renewal and germ layer formation. Nature Cell Biol. 13, 753-761 (2011).
-
(2011)
Nature Cell Biol
, vol.13
, pp. 753-761
-
-
Lyashenko, N.1
-
17
-
-
79955756863
-
Development, maturation, and necessity of transcription factors in the mouse suprachiasmatic nucleus
-
VanDunk, C., Hunter, L. A. & Gray, P. A. Development, maturation, and necessity of transcription factors in the mouse suprachiasmatic nucleus. J. Neurosci. 31, 6457-6467 (2011).
-
(2011)
J. Neurosci.
, vol.31
, pp. 6457-6467
-
-
Vandunk, C.1
Hunter, L.A.2
Gray, P.A.3
-
18
-
-
61449172037
-
Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources
-
Huang, W., Sherman, B. T. & Lempicki, R. A. Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources. Nature Protocols 4, 44-57 (2009).
-
(2009)
Nature Protocols
, vol.4
, pp. 44-57
-
-
Huang, W.1
Sherman, B.T.2
Lempicki, R.A.3
-
19
-
-
0024556115
-
Multiple hepatocyte-enriched nuclear factors function in the regulation of transthyretin and α1-antitrypsin genes
-
Costa, R. H., Grayson, D. R. & Darnell, J. E., Jr. Multiple hepatocyte-enriched nuclear factors function in the regulation of transthyretin and alpha 1-antitrypsin genes. Mol. Cell. Biol. 9, 1415-1425 (1989). (Pubitemid 19095181)
-
(1989)
Molecular and Cellular Biology
, vol.9
, Issue.4
, pp. 1415-1425
-
-
Costa, R.H.1
Grayson, D.R.2
Darnell Jr., J.E.3
-
20
-
-
61349100729
-
Parkinson's disease patient-derived induced pluripotent stem cells free of viral reprogramming factors
-
Soldner, F. et al. Parkinson's disease patient-derived induced pluripotent stem cells free of viral reprogramming factors. Cell 136, 964-977 (2009).
-
(2009)
Cell
, vol.136
, pp. 964-977
-
-
Soldner, F.1
-
21
-
-
69749095203
-
Robustpacemaking in substantia nigra dopaminergic neurons
-
Guzman, J. N., Sanchez-Padilla, J., Chan, C. S. &Surmeier, D. J. Robustpacemaking in substantia nigra dopaminergic neurons. J. Neurosci. 29, 11011-11019 (2009).
-
(2009)
J. Neurosci.
, vol.29
, pp. 11011-11019
-
-
Guzman, J.N.1
Sanchez-Padilla, J.2
Chan, C.S.3
Surmeier, D.J.4
-
22
-
-
0027236205
-
2+ conductances in guinea-pig substantia nigra pars compacta neurones
-
21 conductances in guinea-pig substantia nigra pars compacta neurones. J. Physiol. (Lond.) 466, 727-747 (1993). (Pubitemid 23225251)
-
(1993)
Journal of Physiology
, vol.466
, pp. 727-747
-
-
Nedergaard, S.1
Flatman, J.A.2
Engberg, I.3
-
23
-
-
33750039629
-
Transplanted dopamine neurons derived from primate ES cells preferentially innervate DARPP-32 striatal progenitors within the graft
-
DOI 10.1111/j.1460-9568.2006.05093.x
-
Ferrari, D., Sanchez-Pernaute, R., Lee, H., Studer, L. & Isacson, O. Transplanted dopamine neurons derived from primateEScells preferentially innervate DARPP-32 striatal progenitors within the graft. Eur. J. Neurosci. 24, 1885-1896 (2006). (Pubitemid 44583473)
-
(2006)
European Journal of Neuroscience
, vol.24
, Issue.7
, pp. 1885-1896
-
-
Ferrari, D.1
Sanchez-Pernaute, R.2
Lee, H.3
Studer, L.4
Isacson, O.5
-
24
-
-
0030041034
-
Fetal nigral transplantation as a therapy for Parkinson's disease
-
DOI 10.1016/S0166-2236(96)80038-5
-
Olanow, C. W., Kordower, J. H. & Freeman, T. B. Fetal nigral transplantation as a therapy for Parkinson's disease. Trends Neurosci. 19, 102-109 (1996). (Pubitemid 26059233)
-
(1996)
Trends in Neurosciences
, vol.19
, Issue.3
, pp. 102-109
-
-
Olanow, C.W.1
Kordower, J.H.2
Freeman, T.B.3
-
25
-
-
0031002024
-
Dopamine neuron agenesis in Nurr1-deficient mice
-
DOI 10.1126/science.276.5310.248
-
Zetterström, R. H. et al. Dopamine neuron agenesis in Nurr1-deficient mice. Science 276, 248-250 (1997). (Pubitemid 27172681)
-
(1997)
Science
, vol.276
, Issue.5310
, pp. 248-250
-
-
Zetterstrom, R.H.1
Solomin, L.2
Jansson, L.3
Hoffer, B.J.4
Olson, L.5
Perlmann, T.6
-
26
-
-
57349143739
-
Efficient tumour formation by single human melanoma cells
-
Quintana, E. et al. Efficient tumour formation by single human melanoma cells. Nature 456, 593-598 (2008).
-
(2008)
Nature
, vol.456
, pp. 593-598
-
-
Quintana, E.1
-
27
-
-
79957795795
-
Mir-371-3 expression predicts neural differentiation propensity in human pluripotent stem cells
-
Kim, H. et al. miR-371-3 expression predicts neural differentiation propensity in human pluripotent stem cells. Cell Stem Cell 8, 695-706 (2011).
-
(2011)
Cell Stem Cell
, vol.8
, pp. 695-706
-
-
Kim, H.1
-
28
-
-
77957670482
-
Differentiated parkinson patient-derived induced pluripotent stem cells grow inthe adult rodent brain and reduce motor asymmetry inparkinsonian rats
-
Hargus, G. et al. Differentiated Parkinson patient-derived induced pluripotent stem cells grow inthe adult rodent brain and reduce motor asymmetry inParkinsonian rats. Proc. Natl Acad. Sci. USA 107, 15921-15926 (2010).
-
(2010)
Proc. Natl Acad. Sci. USA
, vol.107
, pp. 15921-15926
-
-
Hargus, G.1
-
29
-
-
55949130712
-
Striatal progenitors derived from human ES cells mature into darpp32 neurons in vitro and in quinolinic acid-lesioned rats
-
Aubry, L. et al. Striatal progenitors derived from human ES cells mature into DARPP32 neurons in vitro and in quinolinic acid-lesioned rats. Proc. Natl Acad. Sci. USA 105, 16707-16712 (2008).
-
(2008)
Proc. Natl Acad. Sci. USA
, vol.105
, pp. 16707-16712
-
-
Aubry, L.1
-
30
-
-
80052157957
-
Efficient generation of transgene-free human induced pluripotent stem cells (iPSCs) by temperature-sensitive sendai virus vectors
-
Ban, H. et al. Efficient generation of transgene-free human induced pluripotent stem cells (iPSCs) by temperature-sensitive Sendai virus vectors. Proc. Natl. Acad. Sci. USA 108, 14234-14239 (2011).
-
(2011)
Proc. Natl. Acad. Sci. USA
, vol.108
, pp. 14234-14239
-
-
Ban, H.1
-
31
-
-
33644684826
-
Transplantation of expanded mesencephalic precursors leads to recovery in parkinsonian rats
-
Studer, L., Tabar, V. & McKay, R. D. Transplantation of expanded mesencephalic precursors leads to recovery in parkinsonian rats. Nature Neurosci. 1, 290-295 (1998).
-
(1998)
Nature Neurosci
, vol.1
, pp. 290-295
-
-
Studer, L.1
Tabar, V.2
McKay, R.D.3
-
32
-
-
0034721690
-
Neurodegeneration prevented by lentiviral vector delivery of GDNF in primate models of parkinson's disease
-
Kordower, J. H. et al. Neurodegeneration prevented by lentiviral vector delivery of GDNF in primate models of Parkinson's disease. Science 290, 767-773 (2000).
-
(2000)
Science
, vol.290
, pp. 767-773
-
-
Kordower, J.H.1
-
34
-
-
68549133201
-
Stepping test in mice:A reliable approach in determining forelimb akinesia in mptp-induced parkinsonism
-
Blume, S. R., Cass, D. K. & Tseng, K. Y. Stepping test in mice:a reliable approach in determining forelimb akinesia in MPTP-induced Parkinsonism. Exp. Neurol. 219, 208-211 (2009).
-
(2009)
Exp. Neurol.
, vol.219
, pp. 208-211
-
-
Blume, S.R.1
Cass, D.K.2
Tseng, K.Y.3
-
36
-
-
0029837256
-
Noninvasive dopamine determination by reversed phase HPLC in the medium of free-floating roller tube cultures of rat fetal ventral mesencephalon: A tool to assess dopaminergic tissue prior to grafting
-
DOI 10.1016/S0361-9230(96)00114-1
-
Studer, L. et al. Noninvasive dopamine determination by reversed phase HPLC in the mediumoffree-floating roller tube cultures ofrat fetal ventral mesencephalon: A tool to assess dopaminergic tissue prior to grafting. Brain Res. Bull. 41, 143-150 (1996). (Pubitemid 26315140)
-
(1996)
Brain Research Bulletin
, vol.41
, Issue.3
, pp. 143-150
-
-
Studer, L.1
Psylla, M.2
Buhler, B.3
Evtouchenko, L.4
Vouga, C.M.5
Leenders, K.L.6
Seiler, R.W.7
Spenger, C.8
-
37
-
-
22444449591
-
Migration and differentiation of neural precursors derived from human embryonic stem cells in the rat brain
-
DOI 10.1038/nbt1088
-
Tabar, V. et al. Migration and differentiation of neural precursors derived from human embryonic stem cells in the rat brain. Nature Biotechnol. 23, 601-606 (2005). (Pubitemid 41724899)
-
(2005)
Nature Biotechnology
, vol.23
, Issue.5
, pp. 601-606
-
-
Tabar, V.1
Panagiotakos, G.2
Greenberg, E.D.3
Chan, B.K.4
Sadelain, M.5
Gutin, P.H.6
Studer, L.7
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