Differentiation of human ES and Parkinson's disease iPS cells into ventral midbrain dopaminergic neurons requires a high activity form of SHH, FGF8a and specific regionalization by retinoic acid

Molecular and Cellular Neuroscience

Volumn 45, Issue 3, 2010, Pages 258-266

  Cooper, Oliver ^a   Hargus, Gunnar ^a   Deleidi, Michela ^a   Blak, Alexandra ^a   Osborn, Teresia ^a   Marlow, Elizabeth ^a   Lee, Kristen ^a   Levy, Adam ^a   Perez Torres, Eduardo ^a   Yow, Alyssa ^a   Isacson, Ole ^a  

^a HARVARD MEDICAL SCHOOL   (United States)

Author keywords

A10; A9; Embryonic; FOXA2; HNF3b; Induced; Neural; Pluripotent; Splice variant; Stem

Indexed keywords

ANTIBODY; BETA TUBULIN; FIBROBLAST GROWTH FACTOR 8; FIBROBLAST GROWTH FACTOR 8A; HEPATOCYTE NUCLEAR FACTOR 3BETA; RETINOIC ACID; SONIC HEDGEHOG PROTEIN; TYROSINE 3 MONOOXYGENASE; UNCLASSIFIED DRUG; WNT1 PROTEIN;

ARTICLE; CONTROLLED STUDY; DOPAMINERGIC NERVE CELL; EMBRYONIC STEM CELL; HUMAN; HUMAN CELL; IMMUNOHISTOCHEMISTRY; MESENCEPHALON; MOTOR DYSFUNCTION; NERVE CELL DIFFERENTIATION; NERVE DEGENERATION; PARKINSON DISEASE; PLURIPOTENT STEM CELL; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL;

ANIMALS; CELL CULTURE TECHNIQUES; CELL DIFFERENTIATION; CELLS, CULTURED; DOPAMINE; EMBRYONIC STEM CELLS; FIBROBLAST GROWTH FACTOR 8; HEDGEHOG PROTEINS; HEPATOCYTE NUCLEAR FACTOR 3-BETA; HUMANS; MESENCEPHALON; MICE; NEURONS; PARKINSON DISEASE; PLURIPOTENT STEM CELLS; TRETINOIN; WNT1 PROTEIN;

ERINACEIDAE; IPS;

EID: 77956613688     PISSN: 10447431     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.mcn.2010.06.017     Document Type: Article

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