Highly efficient neural conversion of human ES and iPS cells by dual inhibition of SMAD signaling

Nature Biotechnology

Volumn 27, Issue 3, 2009, Pages 275-280

  Chambers, Stuart M ^a   Fasano, Christopher A ^a   Papapetrou, Eirini P ^a   Tomishima, Mark ^a   Sadelain, Michel ^a   Studer, Lorenz ^a  

^a MEMORIAL SLOAN KETTERING CANCER CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CELL DENSITIES; CENTRAL NERVOUS SYSTEMS; CO CULTURES; CULTURE CONDITIONS; EMBRYOID BODIES; HUMAN EMBRYONIC STEM (HES) CELL; LOW YIELDS; MIDBRAIN; NEURAL CELLS; NEURAL CRESTS; PLURIPOTENT; REGENERATIVE MEDICINES; SMAD SIGNALING; SYNERGISTIC ACTIONS;

FEEDING; SIGNALING;

CELL CULTURE;

4 [4 (1,3 BENZODIOXOL 5 YL) 5 (2 PYRIDINYL) 1H IMIDAZOL 2 YL]BENZAMIDE; FIBROBLAST GROWTH FACTOR 5; NOGGIN; SMAD PROTEIN; TRANSCRIPTION FACTOR PAX6;

ARTICLE; CELL ASSAY; CELL CULTURE; CELL DENSITY; CELL DIFFERENTIATION; CELL REGENERATION; CENTRAL NERVOUS SYSTEM; CLINICAL PROTOCOL; DISEASE MODEL; EMBRYO; EMBRYONIC STEM CELL; FETUS; GENE INDUCTION; HUMAN; HUMAN CELL; MESENCEPHALON; NEURAL CREST; NEURAL STEM CELL; PLURIPOTENT STEM CELL; PRIORITY JOURNAL; PROGENY; ROSETTE FORMATION; SIGNAL TRANSDUCTION; SPINAL CORD MOTONEURON;

CARRIER PROTEINS; CELL CULTURE TECHNIQUES; CELL DIFFERENTIATION; EMBRYONIC STEM CELLS; HUMANS; MESENCEPHALON; NEURONS; PLURIPOTENT STEM CELLS; SIGNAL TRANSDUCTION; SMAD PROTEINS;

IPS;

EID: 62149125434     PISSN: 10870156     EISSN: 15461696     Source Type: Journal    
DOI: 10.1038/nbt.1529     Document Type: Article

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