P62 positive, TDP-43 negative, neuronal cytoplasmic and intranuclear inclusions in the cerebellum and hippocampus define the pathology of C9orf72-linked FTLD and MND/ALS

Acta Neuropathologica

Volumn 122, Issue 6, 2011, Pages 691-702

  Al Sarraj, Safa ^a,b   King, Andrew ^a,b   Troakes, Claire ^b   Smith, Bradley ^b   Maekawa, Satomi ^a,b   Bodi, Istvan ^a,b   Rogelj, Boris ^b   Al Chalabi, Ammar ^b   Hortobágyi, Tibor ^b   Shaw, Christopher E ^b  

^a KING S COLLEGE HOSPITAL   (United Kingdom)

^b KING'S COLLEGE LONDON   (United Kingdom)

Author keywords

C9orf72; FTLD; MND ALS; p62; TDP43

Indexed keywords

ALPHA INTERNEXIN; ALPHA SYNUCLEIN; FUSED IN SARCOMA PROTEIN; NEUROFILAMENT PROTEIN; PROTEIN; PROTEIN P62; TAR DNA BINDING PROTEIN; UNCLASSIFIED DRUG;

ADULT; AGED; AMYOTROPHIC LATERAL SCLEROSIS; ARTICLE; BRAIN WEIGHT; C9ORF72 GENE; CELL INCLUSION; CELLULAR DISTRIBUTION; CEREBELLUM; CONTROLLED STUDY; FEMALE; FRONTOTEMPORAL DEMENTIA; FRONTOTEMPORAL DEMENTIA WITH AMYOTROPHIC LATERAL SCLEROSIS; FRONTOTEMPORAL DEMENTIA WITH MOTOR NEURON DISEASE; FRONTOTEMPORAL DEMENTIA WITH TDP 43 PROTEINOPATHY; GENE; HEXANUCLEOTIDE REPEAT EXPANSION; HIPPOCAMPUS; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; MALE; MOLECULAR PATHOLOGY; MOTOR NEURON DISEASE; NERVE DEGENERATION; NEURONAL CYTOPLASMIC INCLUSION; NEURONAL INTRANUCLEAR INCLUSION; NEUROPATHOLOGY; NUCLEOTIDE REPEAT; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; PURKINJE CELL; PYRAMIDAL NERVE CELL; TDP 43 PROTEINOPATHY;

ADULT; AGED; AGED, 80 AND OVER; AMYOTROPHIC LATERAL SCLEROSIS; CASE-CONTROL STUDIES; CEREBELLUM; DNA; DNA REPEAT EXPANSION; DNA-BINDING PROTEINS; FEMALE; FRONTOTEMPORAL LOBAR DEGENERATION; HIPPOCAMPUS; HUMANS; INCLUSION BODIES; INTRANUCLEAR INCLUSION BODIES; MALE; MIDDLE AGED; MUTATION; NEURONS; PROTEINS; PURKINJE CELLS; PYRAMIDAL CELLS; RNA-BINDING PROTEINS;

EID: 82355180826     PISSN: 00016322     EISSN: 14320533     Source Type: Journal    
DOI: 10.1007/s00401-011-0911-2     Document Type: Article

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