Mitochondrial parkin recruitment is impaired in neurons derived from mutant PINK1 induced pluripotent stem cells

Journal of Neuroscience

Volumn 31, Issue 16, 2011, Pages 5970-5976

  Seibler, Philip ^a,b   Graziotto, John ^a   Jeong, Hyun ^a   Simunovic, Filip ^a,c   Klein, Christine ^b   Krainc, Dimitri ^a  

^a MASSACHUSETTS GENERAL HOSPITAL   (United States)

^b UNIVERSITY OF LÜBECK   (Germany)

^c Mediterranean Institute for Life Sciences   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CYTOSINE; GLUTAMINE; GLYCINE; GUANINE; MITOCHONDRIAL ENZYME; PARKIN; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA COACTIVATOR 1ALPHA; THYMINE; VALINE;

ANIMAL CELL; ARTICLE; BIOGENESIS; CELL DIFFERENTIATION; CONTROLLED STUDY; DOPAMINERGIC NERVE CELL; ENZYME DEFECT; ENZYME INDUCTION; GENE; HUMAN; HUMAN CELL; MEMBRANE DEPOLARIZATION; MISSENSE MUTATION; MITOCHONDRIAL MEMBRANE POTENTIAL; MOUSE; NONHUMAN; NONSENSE MUTATION; PARKINSON DISEASE; PINK1 GENE; PLURIPOTENT STEM CELL; PRIORITY JOURNAL; PROTEIN EXPRESSION; SKIN FIBROBLAST; WILD TYPE;

ANIMALS; BLOTTING, WESTERN; CELL COUNT; CELLS, CULTURED; FLUORESCENT ANTIBODY TECHNIQUE; HUMANS; INDUCED PLURIPOTENT STEM CELLS; MICE; MICROSCOPY, CONFOCAL; MITOCHONDRIA; NEURONS; PROTEIN KINASES; UBIQUITIN-PROTEIN LIGASES;

EID: 79955786943     PISSN: 02706474     EISSN: 15292401     Source Type: Journal    
DOI: 10.1523/JNEUROSCI.4441-10.2011     Document Type: Article

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