-
1
-
-
79961173182
-
Direct reprogramming of adult human fibroblasts to functional neurons under defined conditions
-
R. Ambasudhan, M. Talantova, R. Coleman, X. Yuan, S. Zhu, S.A. Lipton, and S. Ding Direct reprogramming of adult human fibroblasts to functional neurons under defined conditions Cell Stem Cell 9 2011 113 118
-
(2011)
Cell Stem Cell
, vol.9
, pp. 113-118
-
-
Ambasudhan, R.1
Talantova, M.2
Coleman, R.3
Yuan, X.4
Zhu, S.5
Lipton, S.A.6
Ding, S.7
-
2
-
-
79955884485
-
Modelling schizophrenia using human induced pluripotent stem cells
-
K.J. Brennand, A. Simone, J. Jou, C. Gelboin-Burkhart, N. Tran, S. Sangar, Y. Li, Y. Mu, G. Chen, and D. Yu Modelling schizophrenia using human induced pluripotent stem cells Nature 473 2011 221 225
-
(2011)
Nature
, vol.473
, pp. 221-225
-
-
Brennand, K.J.1
Simone, A.2
Jou, J.3
Gelboin-Burkhart, C.4
Tran, N.5
Sangar, S.6
Li, Y.7
Mu, Y.8
Chen, G.9
Yu, D.10
-
3
-
-
0242353154
-
Vertebrate neurogenesis is counteracted by Sox1-3 activity
-
DOI 10.1038/nn1131
-
M. Bylund, E. Andersson, B.G. Novitch, and J. Muhr Vertebrate neurogenesis is counteracted by Sox1-3 activity Nat. Neurosci. 6 2003 1162 1168 (Pubitemid 37346036)
-
(2003)
Nature Neuroscience
, vol.6
, Issue.11
, pp. 1162-1168
-
-
Bylund, M.1
Andersson, E.2
Novitch, B.G.3
Muhr, J.4
-
4
-
-
80051674431
-
Direct generation of functional dopaminergic neurons from mouse and human fibroblasts
-
M. Caiazzo, M.T. Dell'Anno, E. Dvoretskova, D. Lazarevic, S. Taverna, D. Leo, T.D. Sotnikova, A. Menegon, P. Roncaglia, and G. Colciago Direct generation of functional dopaminergic neurons from mouse and human fibroblasts Nature 476 2011 224 227
-
(2011)
Nature
, vol.476
, pp. 224-227
-
-
Caiazzo, M.1
Dell'Anno, M.T.2
Dvoretskova, E.3
Lazarevic, D.4
Taverna, S.5
Leo, D.6
Sotnikova, T.D.7
Menegon, A.8
Roncaglia, P.9
Colciago, G.10
-
5
-
-
50149098605
-
Induced pluripotent stem cells generated from patients with ALS can be differentiated into motor neurons
-
J.T. Dimos, K.T. Rodolfa, K.K. Niakan, L.M. Weisenthal, H. Mitsumoto, W. Chung, G.F. Croft, G. Saphier, R. Leibel, and R. Goland Induced pluripotent stem cells generated from patients with ALS can be differentiated into motor neurons Science 321 2008 1218 1221
-
(2008)
Science
, vol.321
, pp. 1218-1221
-
-
Dimos, J.T.1
Rodolfa, K.T.2
Niakan, K.K.3
Weisenthal, L.M.4
Mitsumoto, H.5
Chung, W.6
Croft, G.F.7
Saphier, G.8
Leibel, R.9
Goland, R.10
-
6
-
-
58249110796
-
Induced pluripotent stem cells from a spinal muscular atrophy patient
-
A.D. Ebert, J. Yu, F.F. Rose Jr., V.B. Mattis, C.L. Lorson, J.A. Thomson, and C.N. Svendsen Induced pluripotent stem cells from a spinal muscular atrophy patient Nature 457 2009 277 280
-
(2009)
Nature
, vol.457
, pp. 277-280
-
-
Ebert, A.D.1
Yu, J.2
Rose, Jr.F.F.3
Mattis, V.B.4
Lorson, C.L.5
Thomson, J.A.6
Svendsen, C.N.7
-
7
-
-
78049239513
-
Teratomas from pluripotent stem cells: A clinical hurdle
-
C.Y. Fong, K. Gauthaman, and A. Bongso Teratomas from pluripotent stem cells: A clinical hurdle J. Cell. Biochem. 111 2010 769 781
-
(2010)
J. Cell. Biochem.
, vol.111
, pp. 769-781
-
-
Fong, C.Y.1
Gauthaman, K.2
Bongso, A.3
-
8
-
-
0041880122
-
SOX2 functions to maintain neural progenitor identity
-
DOI 10.1016/S0896-6273(03)00497-5
-
V. Graham, J. Khudyakov, P. Ellis, and L. Pevny SOX2 functions to maintain neural progenitor identity Neuron 39 2003 749 765 (Pubitemid 37088088)
-
(2003)
Neuron
, vol.39
, Issue.5
, pp. 749-765
-
-
Graham, V.1
Khudyakov, J.2
Ellis, P.3
Pevny, L.4
-
9
-
-
66149186861
-
Epigenetic hierarchy governing Nestin expression
-
D.W. Han, J.T. Do, M.J. Araúzo-Bravo, S.H. Lee, A. Meissner, H.T. Lee, R. Jaenisch, and H.R. Schöler Epigenetic hierarchy governing Nestin expression Stem Cells 27 2009 1088 1097
-
(2009)
Stem Cells
, vol.27
, pp. 1088-1097
-
-
Han, D.W.1
Do, J.T.2
Araúzo-Bravo, M.J.3
Lee, S.H.4
Meissner, A.5
Lee, H.T.6
Jaenisch, R.7
Schöler, H.R.8
-
10
-
-
84862777308
-
Direct reprogramming of fibroblasts into neural stem cells by defined factors
-
D.W. Han, N. Tapia, A. Hermann, K. Hemmer, S. Höing, M.J. Araúzo-Bravo, H. Zaehres, G. Wu, S. Frank, and S. Moritz Direct reprogramming of fibroblasts into neural stem cells by defined factors Cell Stem Cell 10 2012 465 472
-
(2012)
Cell Stem Cell
, vol.10
, pp. 465-472
-
-
Han, D.W.1
Tapia, N.2
Hermann, A.3
Hemmer, K.4
Höing, S.5
Araúzo-Bravo, M.J.6
Zaehres, H.7
Wu, G.8
Frank, S.9
Moritz, S.10
-
11
-
-
37549030199
-
Treatment of sickle cell anemia mouse model with iPS cells generated from autologous skin
-
J. Hanna, M. Wernig, S. Markoulaki, C.W. Sun, A. Meissner, J.P. Cassady, C. Beard, T. Brambrink, L.C. Wu, T.M. Townes, and R. Jaenisch Treatment of sickle cell anemia mouse model with iPS cells generated from autologous skin Science 318 2007 1920 1923
-
(2007)
Science
, vol.318
, pp. 1920-1923
-
-
Hanna, J.1
Wernig, M.2
Markoulaki, S.3
Sun, C.W.4
Meissner, A.5
Cassady, J.P.6
Beard, C.7
Brambrink, T.8
Wu, L.C.9
Townes, T.M.10
Jaenisch, R.11
-
12
-
-
41949098160
-
Direct Reprogramming of Terminally Differentiated Mature B Lymphocytes to Pluripotency
-
DOI 10.1016/j.cell.2008.03.028, PII S0092867408004479
-
J. Hanna, S. Markoulaki, P. Schorderet, B.W. Carey, C. Beard, M. Wernig, M.P. Creyghton, E.J. Steine, J.P. Cassady, and R. Foreman Direct reprogramming of terminally differentiated mature B lymphocytes to pluripotency Cell 133 2008 250 264 (Pubitemid 351508307)
-
(2008)
Cell
, vol.133
, Issue.2
, pp. 250-264
-
-
Hanna, J.1
Markoulaki, S.2
Schorderet, P.3
Carey, B.W.4
Beard, C.5
Wernig, M.6
Creyghton, MennoP.7
Steine, E.J.8
Cassady, J.P.9
Foreman, R.10
Lengner, C.J.11
Dausman, JessicaA.12
Jaenisch, R.13
-
13
-
-
64249157351
-
Epigenetic reprogramming and induced pluripotency
-
K. Hochedlinger, and K. Plath Epigenetic reprogramming and induced pluripotency Development 136 2009 509 523
-
(2009)
Development
, vol.136
, pp. 509-523
-
-
Hochedlinger, K.1
Plath, K.2
-
14
-
-
50849144675
-
A drug-inducible system for direct reprogramming of human somatic cells to pluripotency
-
D. Hockemeyer, F. Soldner, E.G. Cook, Q. Gao, M. Mitalipova, and R. Jaenisch A drug-inducible system for direct reprogramming of human somatic cells to pluripotency Cell Stem Cell 3 2008 346 353
-
(2008)
Cell Stem Cell
, vol.3
, pp. 346-353
-
-
Hockemeyer, D.1
Soldner, F.2
Cook, E.G.3
Gao, Q.4
Mitalipova, M.5
Jaenisch, R.6
-
15
-
-
79960637387
-
Induction of functional hepatocyte-like cells from mouse fibroblasts by defined factors
-
P. Huang, Z. He, S. Ji, H. Sun, D. Xiang, C. Liu, Y. Hu, X. Wang, and L. Hui Induction of functional hepatocyte-like cells from mouse fibroblasts by defined factors Nature 475 2011 386 389
-
(2011)
Nature
, vol.475
, pp. 386-389
-
-
Huang, P.1
He, Z.2
Ji, S.3
Sun, H.4
Xiang, D.5
Liu, C.6
Hu, Y.7
Wang, X.8
Hui, L.9
-
16
-
-
77955321344
-
Direct reprogramming of fibroblasts into functional cardiomyocytes by defined factors
-
M. Ieda, J.D. Fu, P. Delgado-Olguin, V. Vedantham, Y. Hayashi, B.G. Bruneau, and D. Srivastava Direct reprogramming of fibroblasts into functional cardiomyocytes by defined factors Cell 142 2010 375 386
-
(2010)
Cell
, vol.142
, pp. 375-386
-
-
Ieda, M.1
Fu, J.D.2
Delgado-Olguin, P.3
Vedantham, V.4
Hayashi, Y.5
Bruneau, B.G.6
Srivastava, D.7
-
17
-
-
33748698287
-
Transcriptional repression and DNA hypermethylation of a small set of ES cell marker genes in male germline stem cells
-
M. Imamura, K. Miura, K. Iwabuchi, T. Ichisaka, M. Nakagawa, J. Lee, M. Kanatsu-Shinohara, T. Shinohara, and S. Yamanaka Transcriptional repression and DNA hypermethylation of a small set of ES cell marker genes in male germline stem cells BMC Dev. Biol. 6 2006 34
-
(2006)
BMC Dev. Biol.
, vol.6
, pp. 34
-
-
Imamura, M.1
Miura, K.2
Iwabuchi, K.3
Ichisaka, T.4
Nakagawa, M.5
Lee, J.6
Kanatsu-Shinohara, M.7
Shinohara, T.8
Yamanaka, S.9
-
18
-
-
84856956771
-
Probing sporadic and familial Alzheimer's disease using induced pluripotent stem cells
-
M.A. Israel, S.H. Yuan, C. Bardy, S.M. Reyna, Y. Mu, C. Herrera, M.P. Hefferan, S. Van Gorp, K.L. Nazor, and F.S. Boscolo Probing sporadic and familial Alzheimer's disease using induced pluripotent stem cells Nature 482 2012 216 220
-
(2012)
Nature
, vol.482
, pp. 216-220
-
-
Israel, M.A.1
Yuan, S.H.2
Bardy, C.3
Reyna, S.M.4
Mu, Y.5
Herrera, C.6
Hefferan, M.P.7
Van Gorp, S.8
Nazor, K.L.9
Boscolo, F.S.10
-
19
-
-
65549110335
-
Different transcription factors regulate nestin gene expression during P19 cell neural differentiation and central nervous system development
-
Z. Jin, L. Liu, W. Bian, Y. Chen, G. Xu, L. Cheng, and N. Jing Different transcription factors regulate nestin gene expression during P19 cell neural differentiation and central nervous system development J. Biol. Chem. 284 2009 8160 8173
-
(2009)
J. Biol. Chem.
, vol.284
, pp. 8160-8173
-
-
Jin, Z.1
Liu, L.2
Bian, W.3
Chen, Y.4
Xu, G.5
Cheng, L.6
Jing, N.7
-
21
-
-
64749111225
-
Virus-free induction of pluripotency and subsequent excision of reprogramming factors
-
K. Kaji, K. Norrby, A. Paca, M. Mileikovsky, P. Mohseni, and K. Woltjen Virus-free induction of pluripotency and subsequent excision of reprogramming factors Nature 458 2009 771 775
-
(2009)
Nature
, vol.458
, pp. 771-775
-
-
Kaji, K.1
Norrby, K.2
Paca, A.3
Mileikovsky, M.4
Mohseni, P.5
Woltjen, K.6
-
22
-
-
59349108302
-
Oct4-induced pluripotency in adult neural stem cells
-
J.B. Kim, V. Sebastiano, G. Wu, M.J. Araúzo-Bravo, P. Sasse, L. Gentile, K. Ko, D. Ruau, M. Ehrich, and D. van den Boom Oct4-induced pluripotency in adult neural stem cells Cell 136 2009 411 419
-
(2009)
Cell
, vol.136
, pp. 411-419
-
-
Kim, J.B.1
Sebastiano, V.2
Wu, G.3
Araúzo-Bravo, M.J.4
Sasse, P.5
Gentile, L.6
Ko, K.7
Ruau, D.8
Ehrich, M.9
Van Den Boom, D.10
-
23
-
-
79956357347
-
Direct reprogramming of mouse fibroblasts to neural progenitors
-
J. Kim, J.A. Efe, S. Zhu, M. Talantova, X. Yuan, S. Wang, S.A. Lipton, K. Zhang, and S. Ding Direct reprogramming of mouse fibroblasts to neural progenitors Proc. Natl. Acad. Sci. USA 108 2011 7838 7843
-
(2011)
Proc. Natl. Acad. Sci. USA
, vol.108
, pp. 7838-7843
-
-
Kim, J.1
Efe, J.A.2
Zhu, S.3
Talantova, M.4
Yuan, X.5
Wang, S.6
Lipton, S.A.7
Zhang, K.8
Ding, S.9
-
24
-
-
80755129026
-
Functional integration of dopaminergic neurons directly converted from mouse fibroblasts
-
J. Kim, S.C. Su, H. Wang, A.W. Cheng, J.P. Cassady, M.A. Lodato, C.J. Lengner, C.Y. Chung, M.M. Dawlaty, L.H. Tsai, and R. Jaenisch Functional integration of dopaminergic neurons directly converted from mouse fibroblasts Cell Stem Cell 9 2011 413 419
-
(2011)
Cell Stem Cell
, vol.9
, pp. 413-419
-
-
Kim, J.1
Su, S.C.2
Wang, H.3
Cheng, A.W.4
Cassady, J.P.5
Lodato, M.A.6
Lengner, C.J.7
Chung, C.Y.8
Dawlaty, M.M.9
Tsai, L.H.10
Jaenisch, R.11
-
25
-
-
36849062137
-
Isolation and directed differentiation of neural crest stem cells derived from human embryonic stem cells
-
DOI 10.1038/nbt1365, PII NBT1365
-
G. Lee, H. Kim, Y. Elkabetz, G. Al Shamy, G. Panagiotakos, T. Barberi, V. Tabar, and L. Studer Isolation and directed differentiation of neural crest stem cells derived from human embryonic stem cells Nat. Biotechnol. 25 2007 1468 1475 (Pubitemid 350233140)
-
(2007)
Nature Biotechnology
, vol.25
, Issue.12
, pp. 1468-1475
-
-
Lee, G.1
Kim, H.2
Elkabetz, Y.3
Al Shamy, G.4
Panagiotakos, G.5
Barberi, T.6
Tabar, V.7
Studer, L.8
-
26
-
-
84857136772
-
Direct conversion of mouse fibroblasts to self-renewing, tripotent neural precursor cells
-
E. Lujan, S. Chanda, H. Ahlenius, T.C. Südhof, and M. Wernig Direct conversion of mouse fibroblasts to self-renewing, tripotent neural precursor cells Proc. Natl. Acad. Sci. USA 109 2012 2527 2532
-
(2012)
Proc. Natl. Acad. Sci. USA
, vol.109
, pp. 2527-2532
-
-
Lujan, E.1
Chanda, S.2
Ahlenius, H.3
Südhof, T.C.4
Wernig, M.5
-
27
-
-
80053900492
-
Direct lineage conversion of terminally differentiated hepatocytes to functional neurons
-
S. Marro, Z.P. Pang, N. Yang, M.C. Tsai, K. Qu, H.Y. Chang, T.C. Südhof, and M. Wernig Direct lineage conversion of terminally differentiated hepatocytes to functional neurons Cell Stem Cell 9 2011 374 382
-
(2011)
Cell Stem Cell
, vol.9
, pp. 374-382
-
-
Marro, S.1
Pang, Z.P.2
Yang, N.3
Tsai, M.C.4
Qu, K.5
Chang, H.Y.6
Südhof, T.C.7
Wernig, M.8
-
28
-
-
68249087053
-
Variation in the safety of induced pluripotent stem cell lines
-
K. Miura, Y. Okada, T. Aoi, A. Okada, K. Takahashi, K. Okita, M. Nakagawa, M. Koyanagi, K. Tanabe, and M. Ohnuki Variation in the safety of induced pluripotent stem cell lines Nat. Biotechnol. 27 2009 743 745
-
(2009)
Nat. Biotechnol.
, vol.27
, pp. 743-745
-
-
Miura, K.1
Okada, Y.2
Aoi, T.3
Okada, A.4
Takahashi, K.5
Okita, K.6
Nakagawa, M.7
Koyanagi, M.8
Tanabe, K.9
Ohnuki, M.10
-
29
-
-
0242667922
-
Bmi-1 dependence distinguishes neural stem cell self-renewal from progenitor proliferation
-
DOI 10.1038/nature02060
-
A.V. Molofsky, R. Pardal, T. Iwashita, I.K. Park, M.F. Clarke, and S.J. Morrison Bmi-1 dependence distinguishes neural stem cell self-renewal from progenitor proliferation Nature 425 2003 962 967 (Pubitemid 37376927)
-
(2003)
Nature
, vol.425
, Issue.6961
, pp. 962-967
-
-
Molofsky, A.V.1
Pardal, R.2
Iwashita, T.3
Park, I.-K.4
Clarke, M.F.5
Morrison, S.J.6
-
30
-
-
55849117368
-
Generation of mouse induced pluripotent stem cells without viral vectors
-
K. Okita, M. Nakagawa, H. Hyenjong, T. Ichisaka, and S. Yamanaka Generation of mouse induced pluripotent stem cells without viral vectors Science 322 2008 949 953
-
(2008)
Science
, vol.322
, pp. 949-953
-
-
Okita, K.1
Nakagawa, M.2
Hyenjong, H.3
Ichisaka, T.4
Yamanaka, S.5
-
31
-
-
79960854285
-
Induction of human neuronal cells by defined transcription factors
-
Z.P. Pang, N. Yang, T. Vierbuchen, A. Ostermeier, D.R. Fuentes, T.Q. Yang, A. Citri, V. Sebastiano, S. Marro, T.C. Südhof, and M. Wernig Induction of human neuronal cells by defined transcription factors Nature 476 2011 220 223
-
(2011)
Nature
, vol.476
, pp. 220-223
-
-
Pang, Z.P.1
Yang, N.2
Vierbuchen, T.3
Ostermeier, A.4
Fuentes, D.R.5
Yang, T.Q.6
Citri, A.7
Sebastiano, V.8
Marro, S.9
Südhof, T.C.10
Wernig, M.11
-
32
-
-
79957858519
-
Transcription factor-induced lineage selection of stem-cell-derived neural progenitor cells
-
L. Panman, E. Andersson, Z. Alekseenko, E. Hedlund, N. Kee, J. Mong, C.W. Uhde, Q. Deng, R. Sandberg, and L.W. Stanton Transcription factor-induced lineage selection of stem-cell-derived neural progenitor cells Cell Stem Cell 8 2011 663 675
-
(2011)
Cell Stem Cell
, vol.8
, pp. 663-675
-
-
Panman, L.1
Andersson, E.2
Alekseenko, Z.3
Hedlund, E.4
Kee, N.5
Mong, J.6
Uhde, C.W.7
Deng, Q.8
Sandberg, R.9
Stanton, L.W.10
-
33
-
-
50549089957
-
Disease-specific induced pluripotent stem cells
-
I.H. Park, N. Arora, H. Huo, N. Maherali, T. Ahfeldt, A. Shimamura, M.W. Lensch, C. Cowan, K. Hochedlinger, and G.Q. Daley Disease-specific induced pluripotent stem cells Cell 134 2008 877 886
-
(2008)
Cell
, vol.134
, pp. 877-886
-
-
Park, I.H.1
Arora, N.2
Huo, H.3
Maherali, N.4
Ahfeldt, T.5
Shimamura, A.6
Lensch, M.W.7
Cowan, C.8
Hochedlinger, K.9
Daley, G.Q.10
-
34
-
-
38049187707
-
Reprogramming of human somatic cells to pluripotency with defined factors
-
I.H. Park, R. Zhao, J.A. West, A. Yabuuchi, H. Huo, T.A. Ince, P.H. Lerou, M.W. Lensch, and G.Q. Daley Reprogramming of human somatic cells to pluripotency with defined factors Nature 451 2008 141 146
-
(2008)
Nature
, vol.451
, pp. 141-146
-
-
Park, I.H.1
Zhao, R.2
West, J.A.3
Yabuuchi, A.4
Huo, H.5
Ince, T.A.6
Lerou, P.H.7
Lensch, M.W.8
Daley, G.Q.9
-
35
-
-
79961131135
-
Directed conversion of Alzheimer's disease patient skin fibroblasts into functional neurons
-
L. Qiang, R. Fujita, T. Yamashita, S. Angulo, H. Rhinn, D. Rhee, C. Doege, L. Chau, L. Aubry, and W.B. Vanti Directed conversion of Alzheimer's disease patient skin fibroblasts into functional neurons Cell 146 2011 359 371
-
(2011)
Cell
, vol.146
, pp. 359-371
-
-
Qiang, L.1
Fujita, R.2
Yamashita, T.3
Angulo, S.4
Rhinn, H.5
Rhee, D.6
Doege, C.7
Chau, L.8
Aubry, L.9
Vanti, W.B.10
-
36
-
-
79960649307
-
Direct conversion of mouse fibroblasts to hepatocyte-like cells by defined factors
-
S. Sekiya, and A. Suzuki Direct conversion of mouse fibroblasts to hepatocyte-like cells by defined factors Nature 475 2011 390 393
-
(2011)
Nature
, vol.475
, pp. 390-393
-
-
Sekiya, S.1
Suzuki, A.2
-
37
-
-
84855516409
-
Direct reprogramming of Sertoli cells into multipotent neural stem cells by defined factors
-
C. Sheng, Q. Zheng, J. Wu, Z. Xu, L. Wang, W. Li, H. Zhang, X.Y. Zhao, L. Liu, and Z. Wang Direct reprogramming of Sertoli cells into multipotent neural stem cells by defined factors Cell Res. 22 2012 208 218
-
(2012)
Cell Res.
, vol.22
, pp. 208-218
-
-
Sheng, C.1
Zheng, Q.2
Wu, J.3
Xu, Z.4
Wang, L.5
Li, W.6
Zhang, H.7
Zhao, X.Y.8
Liu, L.9
Wang, Z.10
-
38
-
-
0347719238
-
Expression and function of orphan nuclear receptor TLX in adult neural stem cells
-
DOI 10.1038/nature02211
-
Y. Shi, D. Chichung Lie, P. Taupin, K. Nakashima, J. Ray, R.T. Yu, F.H. Gage, and R.M. Evans Expression and function of orphan nuclear receptor TLX in adult neural stem cells Nature 427 2004 78 83 (Pubitemid 38094825)
-
(2004)
Nature
, vol.427
, Issue.6969
, pp. 78-83
-
-
Shi, Y.1
Lie, D.C.2
Taupin, P.3
Nakashima, K.4
Ray, J.5
Yu, R.T.6
Gage, F.H.7
Evans, R.M.8
-
39
-
-
54949115497
-
Induction of pluripotent stem cells from mouse embryonic fibroblasts by Oct4 and Klf4 with small-molecule compounds
-
Y. Shi, C. Desponts, J.T. Do, H.S. Hahm, H.R. Schöler, and S. Ding Induction of pluripotent stem cells from mouse embryonic fibroblasts by Oct4 and Klf4 with small-molecule compounds Cell Stem Cell 3 2008 568 574
-
(2008)
Cell Stem Cell
, vol.3
, pp. 568-574
-
-
Shi, Y.1
Desponts, C.2
Do, J.T.3
Hahm, H.S.4
Schöler, H.R.5
Ding, S.6
-
40
-
-
79960833952
-
Generation of isogenic pluripotent stem cells differing exclusively at two early onset Parkinson point mutations
-
F. Soldner, J. Laganière, A.W. Cheng, D. Hockemeyer, Q. Gao, R. Alagappan, V. Khurana, L.I. Golbe, R.H. Myers, and S. Lindquist Generation of isogenic pluripotent stem cells differing exclusively at two early onset Parkinson point mutations Cell 146 2011 318 331
-
(2011)
Cell
, vol.146
, pp. 318-331
-
-
Soldner, F.1
Laganière, J.2
Cheng, A.W.3
Hockemeyer, D.4
Gao, Q.5
Alagappan, R.6
Khurana, V.7
Golbe, L.I.8
Myers, R.H.9
Lindquist, S.10
-
41
-
-
80052295767
-
Conversion of mouse and human fibroblasts into functional spinal motor neurons
-
E.Y. Son, J.K. Ichida, B.J. Wainger, J.S. Toma, V.F. Rafuse, C.J. Woolf, and K. Eggan Conversion of mouse and human fibroblasts into functional spinal motor neurons Cell Stem Cell 9 2011 205 218
-
(2011)
Cell Stem Cell
, vol.9
, pp. 205-218
-
-
Son, E.Y.1
Ichida, J.K.2
Wainger, B.J.3
Toma, J.S.4
Rafuse, V.F.5
Woolf, C.J.6
Eggan, K.7
-
42
-
-
55849115999
-
Induced pluripotent stem cells generated without viral integration
-
M. Stadtfeld, M. Nagaya, J. Utikal, G. Weir, and K. Hochedlinger Induced pluripotent stem cells generated without viral integration Science 322 2008 945 949
-
(2008)
Science
, vol.322
, pp. 945-949
-
-
Stadtfeld, M.1
Nagaya, M.2
Utikal, J.3
Weir, G.4
Hochedlinger, K.5
-
43
-
-
33747195353
-
Induction of Pluripotent Stem Cells from Mouse Embryonic and Adult Fibroblast Cultures by Defined Factors
-
DOI 10.1016/j.cell.2006.07.024, PII S0092867406009767
-
K. Takahashi, and S. Yamanaka Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors Cell 126 2006 663 676 (Pubitemid 44233629)
-
(2006)
Cell
, vol.126
, Issue.4
, pp. 663-676
-
-
Takahashi, K.1
Yamanaka, S.2
-
44
-
-
36248966518
-
Induction of Pluripotent Stem Cells from Adult Human Fibroblasts by Defined Factors
-
DOI 10.1016/j.cell.2007.11.019, PII S0092867407014717
-
K. Takahashi, K. Tanabe, M. Ohnuki, M. Narita, T. Ichisaka, K. Tomoda, and S. Yamanaka Induction of pluripotent stem cells from adult human fibroblasts by defined factors Cell 131 2007 861 872 (Pubitemid 350138099)
-
(2007)
Cell
, vol.131
, Issue.5
, pp. 861-872
-
-
Takahashi, K.1
Tanabe, K.2
Ohnuki, M.3
Narita, M.4
Ichisaka, T.5
Tomoda, K.6
Yamanaka, S.7
-
45
-
-
84859555919
-
Direct conversion of fibroblasts into stably expandable neural stem cells
-
M. Thier, P. Wörsdörfer, Y.B. Lakes, R. Gorris, S. Herms, T. Opitz, D. Seiferling, T. Quandel, P. Hoffmann, and M.M. Nöthen Direct conversion of fibroblasts into stably expandable neural stem cells Cell Stem Cell 10 2012 473 479
-
(2012)
Cell Stem Cell
, vol.10
, pp. 473-479
-
-
Thier, M.1
Wörsdörfer, P.2
Lakes, Y.B.3
Gorris, R.4
Herms, S.5
Opitz, T.6
Seiferling, D.7
Quandel, T.8
Hoffmann, P.9
Nöthen, M.M.10
-
46
-
-
77649162059
-
Direct conversion of fibroblasts to functional neurons by defined factors
-
T. Vierbuchen, A. Ostermeier, Z.P. Pang, Y. Kokubu, T.C. Südhof, and M. Wernig Direct conversion of fibroblasts to functional neurons by defined factors Nature 463 2010 1035 1041
-
(2010)
Nature
, vol.463
, pp. 1035-1041
-
-
Vierbuchen, T.1
Ostermeier, A.2
Pang, Z.P.3
Kokubu, Y.4
Südhof, T.C.5
Wernig, M.6
-
47
-
-
42649130264
-
Neurons derived from reprogrammed fibroblasts functionally integrate into the fetal brain and improve symptoms of rats with Parkinson's disease
-
DOI 10.1073/pnas.0801677105
-
M. Wernig, J.P. Zhao, J. Pruszak, E. Hedlund, D. Fu, F. Soldner, V. Broccoli, M. Constantine-Paton, O. Isacson, and R. Jaenisch Neurons derived from reprogrammed fibroblasts functionally integrate into the fetal brain and improve symptoms of rats with Parkinson's disease Proc. Natl. Acad. Sci. USA 105 2008 5856 5861 (Pubitemid 351758462)
-
(2008)
Proceedings of the National Academy of Sciences of the United States of America
, vol.105
, Issue.15
, pp. 5856-5861
-
-
Wernig, M.1
Zhao, J.-P.2
Pruszak, J.3
Hedlund, E.4
Fu, D.5
Soldner, F.6
Broccoli, V.7
Constantine-Paton, M.8
Isacson, O.9
Jaenisch, R.10
-
48
-
-
77955799109
-
Male fetal germ cell differentiation involves complex repression of the regulatory network controlling pluripotency
-
P.S. Western, J.A. van den Bergen, D.C. Miles, and A.H. Sinclair Male fetal germ cell differentiation involves complex repression of the regulatory network controlling pluripotency FASEB J. 24 2010 3026 3035
-
(2010)
FASEB J.
, vol.24
, pp. 3026-3035
-
-
Western, P.S.1
Van Den Bergen, J.A.2
Miles, D.C.3
Sinclair, A.H.4
-
49
-
-
0346462991
-
Molecular Basis for Synergistic Transcriptional Activation by Oct1 and Sox2 Revealed from the Solution Structure of the 42-kDa Oct1 Sox2 Hoxb1-DNA Ternary Transcription Factor Complex
-
DOI 10.1074/jbc.M309790200
-
D.C. Williams Jr., M. Cai, and G.M. Clore Molecular basis for synergistic transcriptional activation by Oct1 and Sox2 revealed from the solution structure of the 42-kDa Oct1.Sox2.Hoxb1-DNA ternary transcription factor complex J. Biol. Chem. 279 2004 1449 1457 (Pubitemid 38082673)
-
(2004)
Journal of Biological Chemistry
, vol.279
, Issue.2
, pp. 1449-1457
-
-
Williams Jr., D.C.1
Cai, M.2
Clore, G.M.3
-
50
-
-
64749083939
-
PiggyBac transposition reprograms fibroblasts to induced pluripotent stem cells
-
K. Woltjen, I.P. Michael, P. Mohseni, R. Desai, M. Mileikovsky, R. Hämäläinen, R. Cowling, W. Wang, P. Liu, and M. Gertsenstein piggyBac transposition reprograms fibroblasts to induced pluripotent stem cells Nature 458 2009 766 770
-
(2009)
Nature
, vol.458
, pp. 766-770
-
-
Woltjen, K.1
Michael, I.P.2
Mohseni, P.3
Desai, R.4
Mileikovsky, M.5
Hämäläinen, R.6
Cowling, R.7
Wang, W.8
Liu, P.9
Gertsenstein, M.10
-
51
-
-
63049090064
-
A fresh look at iPS cells
-
S. Yamanaka A fresh look at iPS cells Cell 137 2009 13 17
-
(2009)
Cell
, vol.137
, pp. 13-17
-
-
Yamanaka, S.1
-
52
-
-
80051684096
-
MicroRNA-mediated conversion of human fibroblasts to neurons
-
A.S. Yoo, A.X. Sun, L. Li, A. Shcheglovitov, T. Portmann, Y. Li, C. Lee-Messer, R.E. Dolmetsch, R.W. Tsien, and G.R. Crabtree MicroRNA-mediated conversion of human fibroblasts to neurons Nature 476 2011 228 231
-
(2011)
Nature
, vol.476
, pp. 228-231
-
-
Yoo, A.S.1
Sun, A.X.2
Li, L.3
Shcheglovitov, A.4
Portmann, T.5
Li, Y.6
Lee-Messer, C.7
Dolmetsch, R.E.8
Tsien, R.W.9
Crabtree, G.R.10
-
53
-
-
36749043230
-
Induced pluripotent stem cell lines derived from human somatic cells
-
J. Yu, M.A. Vodyanik, K. Smuga-Otto, J. Antosiewicz-Bourget, J.L. Frane, S. Tian, J. Nie, G.A. Jonsdottir, V. Ruotti, and R. Stewart Induced pluripotent stem cell lines derived from human somatic cells Science 318 2007 1917 1920
-
(2007)
Science
, vol.318
, pp. 1917-1920
-
-
Yu, J.1
Vodyanik, M.A.2
Smuga-Otto, K.3
Antosiewicz-Bourget, J.4
Frane, J.L.5
Tian, S.6
Nie, J.7
Jonsdottir, G.A.8
Ruotti, V.9
Stewart, R.10
-
54
-
-
65649116572
-
Human induced pluripotent stem cells free of vector and transgene sequences
-
J. Yu, K. Hu, K. Smuga-Otto, S. Tian, R. Stewart, I.I. Slukvin, and J.A. Thomson Human induced pluripotent stem cells free of vector and transgene sequences Science 324 2009 797 801
-
(2009)
Science
, vol.324
, pp. 797-801
-
-
Yu, J.1
Hu, K.2
Smuga-Otto, K.3
Tian, S.4
Stewart, R.5
Slukvin, I.I.6
Thomson, J.A.7
-
55
-
-
80054987997
-
Targeted gene correction of α1-antitrypsin deficiency in induced pluripotent stem cells
-
K. Yusa, S.T. Rashid, H. Strick-Marchand, I. Varela, P.Q. Liu, D.E. Paschon, E. Miranda, A. Ordóñez, N.R.F. Hannan, and F.J. Rouhani Targeted gene correction of α1-antitrypsin deficiency in induced pluripotent stem cells Nature 478 2011 391 394
-
(2011)
Nature
, vol.478
, pp. 391-394
-
-
Yusa, K.1
Rashid, S.T.2
Strick-Marchand, H.3
Varela, I.4
Liu, P.Q.5
Paschon, D.E.6
Miranda, E.7
Ordóñez, A.8
Hannan, N.R.F.9
Rouhani, F.J.10
-
56
-
-
53349178722
-
In vivo reprogramming of adult pancreatic exocrine cells to β-cells
-
Q. Zhou, J. Brown, A. Kanarek, J. Rajagopal, and D.A. Melton In vivo reprogramming of adult pancreatic exocrine cells to β-cells Nature 455 2008 627 632
-
(2008)
Nature
, vol.455
, pp. 627-632
-
-
Zhou, Q.1
Brown, J.2
Kanarek, A.3
Rajagopal, J.4
Melton, D.A.5
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