Enhanced aggregation of androgen receptor in induced pluripotent stem cell-derived neurons from spinal and bulbar muscular atrophy

Journal of Biological Chemistry

Volumn 288, Issue 12, 2013, Pages 8043-8052

  Nihei, Yoshihiro ^a   Ito, Daisuke ^a   Okada, Yohei ^a   Akamatsu, Wado ^a   Yagi, Takuya ^a   Yoshizaki, Takahito ^a   Okano, Hideyuki ^a   Suzuki, Norihiro ^a  

^a KEIO UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

BIOCHEMICAL CHARACTERISTICS; INDUCED PLURIPOTENT STEM CELLS; MOTOR NEURON DISEASE; NEURONAL DIFFERENTIATION; NUCLEAR ACCUMULATION; PATHOGENIC MECHANISMS; POLYGLUTAMINE (POLYQ); POLYGLUTAMINE DISEASE;

BRAIN; CELL CULTURE; GENES; LIGANDS; STEM CELLS;

NEURONS;

ANDROGEN RECEPTOR; ANDROSTANOLONE; GENOMIC DNA; TANESPIMYCIN;

ANDROGEN RECEPTOR GENE; ARTICLE; ATROPHIN 1 GENE; CAG REPEAT; CELL DIFFERENTIATION; CONTROLLED STUDY; DENTATORUBROPALLIDOLUYSIAN ATROPHY; FIBROBLAST; GENE; HUMAN; HUMAN CELL; IMMUNOBLOTTING; IMMUNOFLUORESCENCE; KENNEDY DISEASE; MOTONEURON; MUTANT; NERVE CELL; PHENOTYPE; PLURIPOTENT STEM CELL; PRIORITY JOURNAL; PROTEIN AGGREGATION; PROTEIN EXPRESSION; UPREGULATION;

AGED, 80 AND OVER; ANDROGENS; BASE SEQUENCE; BENZOQUINONES; CELL DIFFERENTIATION; CELLS, CULTURED; DIHYDROTESTOSTERONE; GENE EXPRESSION; GENE EXPRESSION REGULATION; HSP90 HEAT-SHOCK PROTEINS; HUMANS; INDUCED PLURIPOTENT STEM CELLS; LACTAMS, MACROCYCLIC; MALE; MUSCULAR DISORDERS, ATROPHIC; MUTATION; NERVE TISSUE PROTEINS; NEURONS; PROTEIN TRANSPORT; RECEPTORS, ANDROGEN; SEQUENCE ANALYSIS, DNA; TRINUCLEOTIDE REPEATS;

ANIMALIA;

EID: 84875464498     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M112.408211     Document Type: Article

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